Database : MEDLINE
Search on : endocrine and system and diseases [Words]
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[PMID]: 29446585
[Au] Autor:Tarmaeva IY; Hanhareev SS; Bogdanova OG
[Ti] Title:[Assessment of nutrition of students of educational institutions of the various type].
[So] Source:Gig Sanit;95(12):1213-6, 2016.
[Is] ISSN:0016-9900
[Cp] Country of publication:Russia (Federation)
[La] Language:rus
[Ab] Abstract:Among the risk factors that have priority in shaping the health of the population, a leading place is held by a rational nutrition. Presented results indicate to the absence of a stable group eating regularly, with the rational regularity and having all the necessary meals and the recommended food set. In the population of the adult people of the city of Irkutsk there is revealed the role of the nutritional factor in the formation of morbidity rate level of the adult population. It was found that the risk of diseases of the circulatory system accounted of 2.5 (95% CI: 2.1-3.6), for infectious and parasitic diseases - 2.4 (95% CI: 1.7-3.5), for the endocrine system - 2.2 (95% CI: 1.4-3.4), andfor the urinary system - 2.3 (95% CI: 1,7-3,0).
[Mh] MeSH terms primary: Cardiovascular Diseases/epidemiology
Communicable Diseases/epidemiology
Deficiency Diseases
Feeding Behavior
Nutritional Requirements
Nutritional Status
[Mh] MeSH terms secundary: Adult
Deficiency Diseases/epidemiology
Deficiency Diseases/etiology
Feeding Behavior/physiology
Feeding Behavior/psychology
Female
Health Status Disparities
Humans
Male
Public Health/methods
Public Health/statistics & numerical data
Risk Factors
Siberia/epidemiology
Students/statistics & numerical data
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[Js] Journal subset:IM
[Da] Date of entry for processing:180216
[St] Status:MEDLINE

  2 / 16000 MEDLINE  
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[PMID]: 29431342
[Au] Autor:Meshkov NA; Rakhmanov RS; Valtseva EA; Alter TV; Russkova AN; Troshin VV; Fomina YN
[Ti] Title:[Epidemiological and hygiene assessment of the health status of population in the area of the construction site of low-head water power development].
[So] Source:Gig Sanit;95(10):955-61, 2016.
[Is] ISSN:0016-9900
[Cp] Country of publication:Russia (Federation)
[La] Language:rus
[Ab] Abstract:Hydrotechnical facilities have significant environmental and health imyacts. Results of a hygienic assessment of the condition of environmental objects in the area of the yrojected Nizhny Novgorod low-head water ylant develoyment showed that the both air and water pollution level in decentralized water supply sources in Balakhna and Gorodets are lower than in the city of Nizhny Novgorod, and those of the water in the water supply network are higher than in the reference area. A cross-sectional study has revealed in the main grouf (Gorodets, Zavolzhye and Balakhna) the rate of morbidity of nervous system and cardiovascular diseases to be higher than in the reference group (Nizhny Novgorod), with cardiovascular diseases being the largest contributor to the overall grevalence rate in the groug under analysis; and digestive system diseases, in the reference group. The study has no revealed direct correlation between morbidity rate in children and adults and the studied factors. However, a direct relationship has been found between the prevalence rate of endocrine diseases in children and the quality of water in the water supply network in Balakhna District (p<0.007); also, there's a correlation between the morbidity rate of digestive diseases and air pollution and water quality in the water supply network (p<0.009). In the Gorodets District, the same situation has been revealed: the morbidity rate of endocrine diseases in children depends on quality of water from the water supply network (p<0.049); the prevalence rate of digestive diseases, on air pollution and water quality in the water supply network (p<0.048). In the same region in adults the prevalence rate of the nervous system diseases, digestive diseases and diseases of the skin and subcutaneous tissue depends on air pollution and pollution of water in the water supply network (p<0.011, p<0.01 and p<0.02, respectively).
[Mh] MeSH terms primary: Air Pollution
Environmental Illness
Water Pollution
Water Supply
[Mh] MeSH terms secundary: Adult
Air Pollution/adverse effects
Air Pollution/analysis
Child
Cross-Sectional Studies
Environmental Illness/classification
Environmental Illness/epidemiology
Environmental Illness/etiology
Environmental Monitoring/standards
Environmental Monitoring/statistics & numerical data
Health Status
Humans
Industrial Development
Prevalence
Public Health/standards
Public Health/statistics & numerical data
Russia/epidemiology
Water Pollution/adverse effects
Water Pollution/analysis
Water Quality/standards
Water Supply/methods
Water Supply/standards
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[Js] Journal subset:IM
[Da] Date of entry for processing:180213
[St] Status:MEDLINE

  3 / 16000 MEDLINE  
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[PMID]: 29431323
[Au] Autor:Tarmaeva IY; Efimova NV; Baglushkina SY
[Ti] Title:[Hygienic estimation of the nutrition and the risk of morbidity associated with its violation].
[So] Source:Gig Sanit;95(9):868-72, 2016.
[Is] ISSN:0016-9900
[Cp] Country of publication:Russia (Federation)
[La] Language:rus
[Ab] Abstract:Among risk factors possessing a main importance in the shaping of theA public health the leading place is featured to the rational nutrition. Presented results testify to the absence of stable group in the adult population of Irkutsk who eats regularly, with a rational multiplicity and having all essential meal reception and the recommended food package. There was revealed the role of nutrition in shaping of morbidity rate in the adult population. The risk of circulatory diseases was established to account of 2.5 (95% CI 2.1-3.6), the infectious and parasitic diseases - 2.4 (95% CI 1.7-3.5), the endocrine system - 2,2 (95% CI 1.4-3.4), and urinary system - 2.3 (95% CI 1.7 to 3.0).
[Mh] MeSH terms primary: Deficiency Diseases/epidemiology
Feeding Behavior
Nutritional Status
[Mh] MeSH terms secundary: Adolescent
Adult
Aged
Cardiovascular Diseases/epidemiology
Communicable Diseases/epidemiology
Endocrine System Diseases/epidemiology
Female
Humans
Infant
Male
Nutritional Requirements
Risk Assessment
Risk Factors
Siberia/epidemiology
Urologic Diseases/epidemiology
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[Js] Journal subset:IM
[Da] Date of entry for processing:180213
[St] Status:MEDLINE

  4 / 16000 MEDLINE  
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[PMID]: 29350061
[Au] Autor:Münzel T; Sørensen M; Schmidt F; Schmidt E; Steven S; Kröller-Schön S; Daiber A
[Ad] Address:1 The Center for Cardiology, Cardiology 1, Johannes Gutenberg University Medical Center , Mainz, Germany .
[Ti] Title:The Adverse Effects of Environmental Noise Exposure on Oxidative Stress and Cardiovascular Risk.
[So] Source:Antioxid Redox Signal;28(9):873-908, 2018 03 20.
[Is] ISSN:1557-7716
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Epidemiological studies have provided evidence that traffic noise exposure is linked to cardiovascular diseases such as arterial hypertension, myocardial infarction, and stroke. Noise is a nonspecific stressor that activates the autonomous nervous system and endocrine signaling. According to the noise reaction model introduced by Babisch and colleagues, chronic low levels of noise can cause so-called nonauditory effects, such as disturbances of activity, sleep, and communication, which can trigger a number of emotional responses, including annoyance and subsequent stress. Chronic stress in turn is associated with cardiovascular risk factors, comprising increased blood pressure and dyslipidemia, increased blood viscosity and blood glucose, and activation of blood clotting factors, in animal models and humans. Persistent chronic noise exposure increases the risk of cardiometabolic diseases, including arterial hypertension, coronary artery disease, diabetes mellitus type 2, and stroke. Recently, we demonstrated that aircraft noise exposure during nighttime can induce endothelial dysfunction in healthy subjects and is even more pronounced in coronary artery disease patients. Importantly, impaired endothelial function was ameliorated by acute oral treatment with the antioxidant vitamin C, suggesting that excessive production of reactive oxygen species contributes to this phenomenon. More recently, we introduced a novel animal model of aircraft noise exposure characterizing the underlying molecular mechanisms leading to noise-dependent adverse oxidative stress-related effects on the vasculature. With the present review, we want to provide an overview of epidemiological, translational clinical, and preclinical noise research addressing the nonauditory, adverse effects of noise exposure with focus on oxidative stress. Antioxid. Redox Signal. 28, 873-908.
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Entry month:1801
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:In-Process
[do] DOI:10.1089/ars.2017.7118

  5 / 16000 MEDLINE  
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[PMID]: 28465449
[Au] Autor:Geller BM; Nelson HD; Weaver DL; Frederick PD; Allison KH; Onega T; Carney PA; Tosteson ANA; Elmore JG
[Ad] Address:Department of Family Medicine, University of Vermont, Burlington, Vermont, USA.
[Ti] Title:Characteristics associated with requests by pathologists for second opinions on breast biopsies.
[So] Source:J Clin Pathol;70(11):947-953, 2017 Nov.
[Is] ISSN:1472-4146
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:AIMS: Second opinions in pathology improve patient safety by reducing diagnostic errors, leading to more appropriate clinical treatment decisions. Little objective data are available regarding the factors triggering a request for second opinion despite second opinion consultations being part of the diagnostic system of pathology. Therefore we sought to assess breast biopsy cases and interpreting pathologists characteristics associated with second opinion requests. METHODS: Collected pathologist surveys and their interpretations of 60 test set cases were used to explore the relationships between case characteristics, pathologist characteristics and case perceptions, and requests for second opinions. Data were evaluated by logistic regression and generalised estimating equations. RESULTS: 115 pathologists provided 6900 assessments; pathologists requested second opinions on 70% (4827/6900) of their assessments 36% (1731/4827) of these would not have been required by policy. All associations between case characteristics and requesting second opinions were statistically significant, including diagnostic category, breast density, biopsy type, and number of diagnoses noted per case. Exclusive of institutional policies, pathologists wanted second opinions most frequently for atypia (66%) and least frequently for invasive cancer (20%). Second opinion rates were higher when the pathologist had lower assessment confidence, in cases with higher perceived difficulty, and cases with borderline diagnoses. CONCLUSIONS: Pathologists request second opinions for challenging cases, particularly those with atypia, high breast density, core needle biopsies, or many co-existing diagnoses. Further studies should evaluate whether the case characteristics identified in this study could be used as clinical criteria to prompt system-level strategies for mandating second opinions.
[Mh] MeSH terms primary: Biopsy
Breast Diseases/pathology
Breast/pathology
Pathologists
Referral and Consultation
[Mh] MeSH terms secundary: Adult
Aged
Attitude of Health Personnel
Clinical Competence
Cross-Sectional Studies
Diagnosis, Differential
Diagnostic Errors/prevention & control
Female
Health Knowledge, Attitudes, Practice
Humans
Logistic Models
Male
Middle Aged
Observer Variation
Pathologists/psychology
Predictive Value of Tests
Reproducibility of Results
[Pt] Publication type:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Entry month:1711
[Cu] Class update date: 180307
[Lr] Last revision date:180307
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:170504
[St] Status:MEDLINE
[do] DOI:10.1136/jclinpath-2016-204231

  6 / 16000 MEDLINE  
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[PMID]: 29260765
[Au] Autor:Smolyar NI; Chukhray NL
[Ad] Address:Danylo Halytskiy Lviv National Medical University, Lviv, Ukraine.
[Ti] Title:Somaticheskaia patologiia kak faktor, otiagoshchaiushchii formirovanie rezistentnosti émali postoiannykh zubov. [Somatic pathology as a negative factor of enamel resistance of the permanent teeth].
[So] Source:Stomatologiia (Mosk);96(6):44-47, 2017.
[Is] ISSN:0039-1735
[Cp] Country of publication:Russia (Federation)
[La] Language:rus
[Ab] Abstract:According to a survey of 292 children of 7, 12 and 15 years from Lviv it was assessed the resistance of enamel of permanent teeth by various somatic diseases. Caries susceptible enamel was most frequently revealed in children with gastrointestinal diseases and allergic diseases (66.67±12.17 and 83.33±10.76%, respectively), as well as endocrine disorders (55.00±7.87%). In children with musculoskeletal system diseases caries resistant and conditionally caries resistant enamel (23.08±8.26 and 26.92±8.70%) was seen two times less than caries susceptible enamel (50.00±9.81%, p <0.001, p <0,001). The findings suggest that the somatic pathology reduced structural and functional resistance of enamel, which leads to lower resistance of dental hard tissues under the influence of cariogenic factors.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 180306
[Lr] Last revision date:180306
[St] Status:In-Process
[do] DOI:10.17116/stomat201796644-48

  7 / 16000 MEDLINE  
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[PMID]: 29220864
[Au] Autor:Natale G; Ryskalin L; Busceti CL; Biagioni F; Fornai F
[Ti] Title:The nature of catecholamine-containing neurons in the enteric nervous system in relationship with organogenesis, normal human anatomy and neurodegeneration.
[So] Source:Arch Ital Biol;155(3):118-130, 2017 Sep 01.
[Is] ISSN:0003-9829
[Cp] Country of publication:Italy
[La] Language:eng
[Ab] Abstract:The gastrointestinal tract is provided with extrinsic and intrinsic innervation. The extrinsic innervation includes the classic vagal parasympathetic and sympathetic components, with afferent sensitive and efferent secretomotor fibers. The intrinsic innervations is represented by the enteric nervous system (ENS), which is recognized as a complex neural network controlling a variety of cell populations, including smooth muscle cells, mucosal secretory cells, endocrine cells, microvasculature, immune and inflammatory cells. This is finalized to regulate gastrointestinal secretion, absorption and motility. In particular, this network is organized in several plexuses each one providing quite autonomous control of gastrointestinal functions (hence the definition of "second brain"). The similarity between ENS and CNS is further substantiated by the presence of local sensitive pseudo- unipolar ganglionic neurons with both peripheral and central branching which terminate in the enteric wall. A large variety of neurons and neurotransmitters takes part in the ENS. However, the nature of these neurons and their role in the regulation of gastrointestinal functions is debatable. In particular, the available literature reporting the specific nature of catecholamine- containing neurons provides conflicting evidence. This is critical both for understanding the specific role of each catecholamine in the gut and, mostly, to characterize specifically the enteric neuropathology occurring in a variety of diseases. An emphasis is posed on neurodegenerative disorders, such as Parkinson's disease, which is associated with the loss of catecholamine neurons. In this respect, the recognition of the nature of such neurons within the ENS would contribute to elucidate the pathological mechanisms which produce both CNS and ENS degeneration and to achieve more effective therapeutic approaches. Despite a great emphasis is posed on the role of noradrenaline to regulate enteric activities only a few reports are available on the anatomy and physiology of enteric dopamine neurons. Remarkably, this review limits the presence of enteric noradrenaline (and adrenaline) only within extrinsic sympathetic nerve terminals. This is based on careful morphological studies showing that the only catecholamine-containing neurons within ENS would be dopaminergic. This means that enteric pathology of catecholamine neurons should be conceived as axon pathology for noradrenaline neurons and whole cell pathology for dopamine neurons which would be the sole catecholamine cell within intrinsic circuitries affecting gut motility and secretions.The gastrointestinal tract is provided with extrinsic and intrinsic innervation. The extrinsic innervation includes the classic vagal parasympathetic and sympathetic components, with afferent sensitive and efferent secretomotor fibers. The intrinsic innervations is represented by the enteric nervous system (ENS), which is recognized as a complex neural network  controlling a variety of cell populations, including smooth muscle cells, mucosal secretory cells, endocrine cells, microvasculature, immune and inflammatory cells. This is finalized to regulate gastrointestinal secretion, absorption and motility. In particular, this network is organized in several plexuses each one providing quite autonomous control of gastrointestinal functions (hence the definition of "second brain"). The similarity between ENS and CNS is further substantiated by the presence of local sensitive pseudounipolar ganglionic neurons with both peripheral and central branching which terminate in the enteric wall. A large variety of neurons and neurotransmitters takes part in the ENS. However, the nature of these neurons and their role in the regulation of gastrointestinal functions is debatable. In particular, the available literature reporting the specific nature of catecholamine-containing neurons provides conflicting evidence. This is critical both for understanding the specific role of each catecholamine in the gut and, mostly, to characterize specifically the enteric neuropathology occurring in a variety of diseases. An emphasis is posed on neurodegenerative disorders, such as including Parkinson's disease, which is associated with the loss of catecholamine neurons. In this respect, the recognition of the nature of such neurons within the ENS would contribute to elucidate the pathological mechanisms which produce both CNS and ENS degeneration and to achieve more effective therapeutic approaches. Despite a great emphasis is posed on the role of noradrenaline to regulate enteric activities only a few reports are available on the anatomy and physiology of enteric dopamine neurons. Remarkably, this review limits the presence of enteric noradrenaline (and adrenaline) only within extrinsic sympathetic nerve terminals. This is based on careful morphological studies showing that the only catecholamine-containing neurons within ENS would be dopaminergic. This means that enteric pathology of catecholamine neurons should be conceived as axon pathology for noradrenaline neurons and whole cell pathology for dopamine neurons which would be the sole catecholamine cell within intrinsic circuitries affecting gut motility and secretions.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 180306
[Lr] Last revision date:180306
[St] Status:In-Process
[do] DOI:10.12871/00039829201733

  8 / 16000 MEDLINE  
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[PMID]: 29477446
[Au] Autor:ThyagaRajan S; Hima L; Pratap UP; Priyanka HP; Vasantharekha R
[Ad] Address:Integrative Medicine Laboratory, Department of Biotechnology, School of Bioengineering, SRM University, Kattankulathur 603 203, Tamil Nadu, India. Electronic address: thyagarajan.s@ktr.srmuniv.ac.in.
[Ti] Title:Estrogen-induced neuroimmunomodulation as facilitator of and barrier to reproductive aging in brain and lymphoid organs.
[So] Source:J Chem Neuroanat;, 2018 Feb 27.
[Is] ISSN:1873-6300
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:Reproductive aging in females is marked by alterations in gonadal hormones, estrogen and progesterone, that facilitate cessation of reproductive cycles and onset of female-specific diseases such as autoimmune and neurodegenerative diseases, hormone-dependent cancers, and osteoporosis. Bidirectional communication between the three homeostatic systems, nervous system, endocrine system, and immune system, is essential for the maintenance of health and any dysfunction in the cross-talk promotes the development of diseases and cancer. The pleiotropic effects of estrogen on neural-immune interactions may promote either neuroprotection or inflammatory conditions depending on the site of action, dose and duration of treatment, type of estrogen receptors and its influence on intracellular signaling pathways, etc. Our studies involving treatment of early middle-aged female rats with low and high doses of estrogen and examining the brain areas, thymus, spleen, and lymph nodes revealed that estrogen-induced changes in neural-immune interactions are markedly affected in thymus followed by spleen and lymph nodes while it confers neuroprotection in the brain areas. These alterations are determined by antioxidant enzyme status, growth factors, intracellular signaling pathways involved in cell survival and inflammation, and metabolic enzymes and thus, may regulate the various stages in female reproductive aging. It is imperative that detailed longitudinal studies are carried out to understand the mechanisms of neuroendocrine-immune interactions in reproductive aging to facilitate healthy aging and for the development of better treatment strategies for female-specific diseases.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1802
[Cu] Class update date: 180303
[Lr] Last revision date:180303
[St] Status:Publisher

  9 / 16000 MEDLINE  
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[PMID]: 29498601
[Au] Autor:Bussat A; Proisy M; Bruneau B; Bouzillé G; Chappé C; Riffaud L
[Ad] Address:Departments of 1 Ophthalmology.
[Ti] Title:Edema of the optic tract in patients with tumors of the sellar region: clinical and visual implications in the pediatric population.
[So] Source:J Neurosurg Pediatr;:1-7, 2018 Mar 02.
[Is] ISSN:1933-0715
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVE Tumor-related edema of the optic tract (EOT) corresponds to a preferential posterior distribution of peritumoral edema along the white matter tract of the visual system. To date, the consequences of EOT have never been evaluated specifically in the pediatric population. In this study, the authors attempted to identify clinical and radiological features associated with the development of EOT and the specific influence of this edema on visual function. METHODS A retrospective review was performed of data collected from patients younger than 18 years who underwent surgery for a tumor in the sellar region at the authors' institution between January 2005 and January 2016. Data were collected on patient characteristics, ophthalmological evaluations, and neuroimaging findings. To evaluate and compare visual function impairment, ophthalmological data were converted to a global visual function score, which took into account visual acuity, visual field evaluations, and laterality deficiencies. The visual acuity score was defined according to the International Classification of Diseases, 10th Revision. Visual field deficiencies were converted to a score of 0-2. Two opposing groups were then distinguished according to the presence or absence of EOT. Visual acuity, visual field results, and global scores were compared between groups before and after treatment. RESULTS Twenty-six patients were included in the study: 17 patients with craniopharyngioma, 3 patients with pilocytic astrocytoma, 2 patients with ganglioglioma, 2 patients with germ cell tumor, 1 patient with macroprolactinoma, and 1 patient with Rathke's cleft cyst. There were 11 children in the group with edema and 15 children in the group without edema. None of the following criteria were statistically different between the 2 groups: age, sex, clinical symptoms at presentation (endocrine deficiency or intracranial hypertension signs), incidence of hydrocephalus, compression of the optic tracts and mass effect on the optic chiasm, tumor size and localization, presence of intratumoral cysts, treatment, type of tumor, or recurrence. The median global visual function and visual acuity scores were not significantly different between the groups either at presentation or at final evaluation. The visual field score was lower (i.e., more deficiency) in the group with edema than in the group without edema (p < 0.05); 89% of the patients with edema had severe or mild visual field impairment versus only 40% of the patients without edema. At the final examination after treatment, the visual field scores were not different between the 2 groups. Although not significant, the number of patients with optic disc pallor was greater in the group without edema both at diagnosis and at final examination. CONCLUSIONS This study confirms that EOT in the context of sellar region tumor in children is not necessarily associated with a less-favorable visual prognosis.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180302
[Lr] Last revision date:180302
[St] Status:Publisher
[do] DOI:10.3171/2017.11.PEDS17526

  10 / 16000 MEDLINE  
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[PMID]: 29424996
[Au] Autor:Filatova OV; Kovrigin AO; Voronina IY; Pavlova IP; Balanova AV
[Ti] Title:[Features of physical development of girls residing in the altai territory with the different level of the environmental load].
[So] Source:Gig Sanit;95(7):643-8, 2016.
[Is] ISSN:0016-9900
[Cp] Country of publication:Russia (Federation)
[La] Language:rus
[Ab] Abstract:There was performed the determination of the characteristics of the physical development of 660 girls aged of from 6 years 6 months to 17years 5 months 29 days, residing in the Blagoveshchenskiy and the Ust-Pristanskiy regions of the Altai Krai. The Blagoveshchenskiy region is characterized by a high level of ambient air pollution (potential of the atmospheric pollution accounts for 2.7-3.0). Sodium sulfate, sulfur dioxide, hydrogen sulfide, carbonic oxide, nitrogen dioxide, vanadium pentoxide, ammonia, manganese and its compounds, hexavalent chromium make the greatest contribution to the atmospheric pollution. The Ust-Pristanskiy region is referred to the least polluted territories of the Altai Krai. Living conditions in the Blagoveshchenskiy region of the Altai Krai were found to influence on the girls ' physical and sexual development. The girls living in the Blagoveshchenskiy region show the pubertal growth spurt one year later, which is lasting longer. As a result, by the age of 17, measurements of the body and leg length are almost 6 cm higher in girls of the Blagoveshchenskiy region. 97% of the Blagoveshchenskiy region residents have pathological (trochanter index ≤ 1.85) and disevolutive (trochanter index = 1.86 - 1.91) types of age evolution which testifies to the thyroid and reproductive hormones deficiency. Among the residents of the Ust-Pristanskiy region, 80% have either normal values of the trochanter index (1.95 - 2.0) or slightly deviated from the norm (hypoevolutive, normoevolutive, and hyperevolutive types of age evolution). The level of the endocrine system diseases prevalence, nutrition and metabolic disorders among the teenagers of the Blagoveshchenskiy region are 2.5 times higher than in the rural area of the Altai Krai. The relative risk of the endocrine system diseases occurrence, nutrition disturbances and metabolic disorders in the teenagers of the Blagoveshchenskiy region equals to OR=1.87 (x=272.7, p<0.001).
[Mh] MeSH terms primary: Adolescent Development/physiology
Child Development/physiology
Environmental Exposure
Environmental Illness
[Mh] MeSH terms secundary: Adolescent
Child
Environmental Exposure/analysis
Environmental Exposure/prevention & control
Environmental Exposure/statistics & numerical data
Environmental Illness/epidemiology
Environmental Illness/prevention & control
Environmental Monitoring/methods
Environmental Monitoring/statistics & numerical data
Female
Humans
Prevalence
Siberia/epidemiology
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180301
[Lr] Last revision date:180301
[Js] Journal subset:IM
[Da] Date of entry for processing:180210
[St] Status:MEDLINE


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