Database : MEDLINE
Search on : furcation and defects [Words]
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[PMID]: 29218735
[Au] Autor:Aimetti M; Mariani GM; Ercoli E; Audagna M; Romano F
[Ad] Address:Department of Surgical Sciences, C.I.R. Dental School, University of Turin, Turin, Italy.
[Ti] Title:Soft tissue re-growth after osseous resective surgery with and without fibre retention technique. Four-year follow-up of a randomized clinical trial.
[So] Source:J Clin Periodontol;45(3):364-372, 2018 Mar.
[Is] ISSN:1600-051X
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:AIM: The aim of this study was to compare the clinical outcomes and soft tissue rebound following Fibre Retention Osseous Resective Surgery (FibReORS) and Osseous Resective Surgery (ORS) over a 48-month period. MATERIALS AND METHODS: Thirteen chronic periodontitis patients, displaying two contra-lateral posterior sextants with residual intrabony defects ≤3 mm in single-rooted or multi-rooted teeth with no or grade I furcation involvement, were treated in a split-mouth study model. ORS procedure was randomly applied on one side, while FibReORS on the contra-lateral side. Clinical measurements were recorded at 12 and 48 months after surgery. RESULTS: All 13 patients were available for the 48-month recall. At this time point, probing depth (PD) and keratinized tissue changes did not significantly differ between treatments. FibReORS-treated sites exhibited less gingival recession than ORS-treated sextants (2.1 ± 0.3 versus 2.5 ± 0.4 mm, p = .001), but comparable coronal soft tissue rebound. The mean difference of 0.4 ± 0.3 mm was consistent with higher amount of bone resection in the ORS group (0.92 ± 0.11 versus 0.38 ± 0.09 mm, p < .001). CONCLUSION: FibReORS resulted in similar PD changes and soft tissue rebound compared with ORS in posterior teeth with no or limited furcation involvement.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 180213
[Lr] Last revision date:180213
[St] Status:In-Data-Review
[do] DOI:10.1111/jcpe.12848

  2 / 1068 MEDLINE  
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[PMID]: 29288504
[Au] Autor:Nuñez J; Sanchez N; Vignoletti F; Sanz-Martin I; Caffesse R; Santamaria S; Garcia-Sanz JA; Sanz M
[Ad] Address:Section of Periodontology, Faculty of Odontology, University Complutense of Madrid, Madrid, Spain.
[Ti] Title:Cell therapy with allogenic canine periodontal ligament-derived cells in periodontal regeneration of critical size defects.
[So] Source:J Clin Periodontol;, 2017 Dec 29.
[Is] ISSN:1600-051X
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:AIM: The objective of this in vivo experimental study to evaluate the regenerative potential of a cell therapy combining allogenic periodontal ligament-derived cells within a xenogeneic bone substitute in a similar experimental model. METHODS: In nine beagle dogs, critical size 6-mm supra-alveolar periodontal defects were created around the PIII and PIV. The resulting supra-alveolar defects were randomly treated with either 1.4 × 10 allogenic canine periodontal ligament-derived cells seeded on de-proteinized bovine bone mineral with 10% collagen (DBBM-C) (test group) or DBBM-C without cells (control group). Specimens were obtained at 3 months, and histological outcomes were studied. RESULTS: The histological analysis showed that total furcation closure occurred very seldom in both groups, being the extent of periodontal regeneration located in the apical third of the defect. The calculated amount of periodontal regeneration at the furcation area was comparable in both the test and control groups (1.93 ± 1.14 mm (17%) versus 2.35 ± 1.74 mm (22%), respectively (p = .37). Similarly, there were no significant differences in the amount of new cementum formation 4.49 ± 1.56 mm (41%) versus 4.97 ± 1.05 mm (47%), respectively (p = .45). CONCLUSIONS: This experimental study was unable to demonstrate the added value of allogenic cell therapy in supra-crestal periodontal regeneration.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 180129
[Lr] Last revision date:180129
[St] Status:Publisher
[do] DOI:10.1111/jcpe.12863

  3 / 1068 MEDLINE  
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[PMID]: 29322600
[Au] Autor:Masaeli R; Zandsalimi K; Lotfi Z; Tayebi L
[Ad] Address:Dental Biomaterials Department, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
[Ti] Title:Using Enamel Matrix Derivative to Improve Treatment Efficacy in Periodontal Furcation Defects.
[So] Source:J Prosthodont;, 2018 Jan 11.
[Is] ISSN:1532-849X
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:PURPOSE: Furcations are complicated periodontal defects. Untreated furcations lead to loss of the involved teeth and supporting tissues. It has been demonstrated that regenerative biomaterials are beneficial in reconstruction of the bone surrounding furcation-affected teeth. These biomaterials range from bone grafts and nonresorbable/resorbable barrier membranes to biologics that are able to trigger inactive regenerative processes in periodontal tissues. Selection of appropriate material(s) to treat furcations is challenging. The aim of this article is to provide a comparative outlook on different biomaterials applicable in regeneration of furcations with a focus on enamel matrix derivative (EMD). METHODS: Scientific databases including PubMed/MEDLINE, ScienceDirect, and EMBASE were searched, and 28 articles were found primarily for this specific study. Full texts were studied to identify relevant studies; 17 studies were excluded because of irrelevancy, while 11 main studies were ultimately selected. Other references have been used for general statements. RESULTS: EMD is a protein complex widely used in the regeneration of different periodontal defects. To assess the effects of EMD for treatment of root furcations, clinical studies involving EMD with and without barrier membranes and bone grafts were selected and compared. Briefly, this study reveals that when EMD is combined with open flap debridement (OFD), guided tissue regeneration (GTR), or bone grafting (BG), the amount of class II furcations converted to class I increases significantly. EMD also reduces tissue swelling and patient discomfort after treatment. CONCLUSIONS: This study provides evidence to find the best combination of biomaterials to treat furcation defects. The best results are obtained if EMD is combined with ß-TCP/HA alloplastic bone grafts.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1801
[Cu] Class update date: 180111
[Lr] Last revision date:180111
[St] Status:Publisher
[do] DOI:10.1111/jopr.12753

  4 / 1068 MEDLINE  
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[PMID]: 29197444
[Au] Autor:Natto ZS; Green MS
[Ti] Title:A Leukocyte- and Platelet-Rich Fibrin Showed a Regenerative Potential in Intrabony Defects and Furcation Defects but Not in Periodontal Plastic Surgery.
[So] Source:J Evid Based Dent Pract;17(4):408-410, 2017 Dec.
[Is] ISSN:1532-3390
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Regenerative potential of leucocyte- and platelet-rich fibrin. Part A: intra-bony defects, furcation defects and periodontal plastic surgery. A systematic review and meta-analysis. Castro AB, Meschi N, Temmerman A, Pinto N, Lambrechts P, Teughels W, Quirynen M. J Clin Periodontol 2017; 44(1):67-82. SOURCE OF FUNDING: Self-funded by the authors and their institution TYPE OF STUDY/DESIGN: Systematic review with meta-analysis of data.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 171203
[Lr] Last revision date:171203
[St] Status:In-Data-Review

  5 / 1068 MEDLINE  
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[PMID]: 29197436
[Au] Autor:McGowan T; McGowan K; Ivanovski S
[Ad] Address:Department of Periodontology, School of Dentistry and Oral Health, Griffith University, Gold Coast, Queensland, Australia. Electronic address: troy.mcgowan@griffithuni.edu.au.
[Ti] Title:A Novel Evidence-Based Periodontal Prognosis Model.
[So] Source:J Evid Based Dent Pract;17(4):350-360, 2017 Dec.
[Is] ISSN:1532-3390
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVE: Patients with periodontal disease and the dental professionals responsible for their care want to know which teeth are expected to respond favorably to periodontal treatment and which teeth are likely to be lost in the short and long term. A number of different periodontal prognosis systems have been previously proposed but do not consider important patient-level factors, such as smoking and diabetic control, in the calculation of the expected outcome and often use subjective measures that introduce potential inaccuracies. The aim of this report is to translate the best available evidence on periodontal prognosis into a clinical model to facilitate decision-making and improve patient outcomes. METHODS: Criteria for an ideal prognostic system were proposed and used to assess the previously reported models. With an emphasis on the inclusion of patient-level modifiers (PLMs) and the exclusive use of objective parameters, a new evidence-based model was developed. RESULTS: This report proposes a new tooth-level prognosis model that uses 9 evidence-based quantifiable parameters to provide a prognosis of secure, doubtful, poor, or irrational to treat. Six tooth-level risk predictors (bone loss:age, pocket depth, furcation involvement, infrabony defects, anatomical factors, and mobility) and 3 PLMs (smoking, diabetes, and bleeding on probing) are used to determine the expected course of disease with specific reference to the suitability of the tooth for future dental treatment. CONCLUSIONS: PLMs must be considered when determining the prognosis of a tooth with periodontal disease. The model proposed in this report is based on the best available evidence for factors affecting tooth survival and has been designed to be as simple and objective as possible to facilitate its adoption in clinical practice. It will be retrospectively and prospectively validated to determine its ability to accurately predict the course of disease.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 171203
[Lr] Last revision date:171203
[St] Status:In-Data-Review

  6 / 1068 MEDLINE  
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[PMID]: 29042732
[Au] Autor:Padmanabhan S; Dommy A; Guru SR; Joseph A
[Ad] Address:Department of Periodontics, Vydehi Institute of Dental Sciences and Research Centre, Bengaluru, Karnataka, India.
[Ti] Title:Comparative Evaluation of Cone-beam Computed Tomography versus Direct Surgical Measurements in the Diagnosis of Mandibular Molar Furcation Involvement.
[So] Source:Contemp Clin Dent;8(3):439-445, 2017 Jul-Sep.
[Is] ISSN:0976-237X
[Cp] Country of publication:India
[La] Language:eng
[Ab] Abstract:AIM: Periodontists frequently experience inconvenience in accurate assessment and treatment of furcation areas affected by periodontal disease. Furcation involvement (FI) most commonly affects the mandibular molars. Diagnosis of furcation-involved teeth is mainly by the assessment of probing pocket depth, clinical attachment level, furcation entrance probing, and intraoral periapical radiographs. Three-dimensional imaging has provided advantage to the clinician in assessment of bone morphology. Thus, the present study aimed to compare the diagnostic efficacy of cone-beam computed tomography (CBCT) as against direct intrasurgical measurements of furcation defects in mandibular molars. SUBJECTS AND METHODS: Study population included 14 patients with 25 mandibular molar furcation sites. CBCT was performed to measure height, width, and depth of furcation defects of mandibular molars with Grade II and Grade III FI. Intrasurgical measurements of the FI were assessed during periodontal flap surgery in indicated teeth which were compared with CBCT measurements. Statistical analysis was done using paired -test and Bland-Altman plot. RESULTS: The CBCT versus intrasurgical furcation measurements were 2.18 ± 0.86 mm and 2.30 ± 0.89 mm for furcation height, 1.87 ± 0.52 mm and 1.84 ± 0.49 mm for furcation width, and 3.81 ± 1.37 mm and 4.05 ± 1.49 mm for furcation depth, respectively. Results showed that there was no statistical significance between the measured parameters, indicating that the two methods were statistically similar. CONCLUSION: Accuracy of assessment of mandibular molar FI by CBCT was comparable to that of direct surgical measurements. These findings indicate that CBCT is an excellent adjunctive diagnostic tool in periodontal treatment planning.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171022
[Lr] Last revision date:171022
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.4103/ccd.ccd_515_17

  7 / 1068 MEDLINE  
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[PMID]: 28967334
[Au] Autor:Kim DM; Bassir SH
[Ad] Address:Department of Oral Medicine, Infection and Immunity, Division of Periodontology, Harvard School of Dental Medicine, Boston, MA.
[Ti] Title:When Is Cone-Beam Computed Tomography Imaging Appropriate for Diagnostic Inquiry in the Management of Inflammatory Periodontitis? An American Academy of Periodontology Best Evidence Review.
[So] Source:J Periodontol;88(10):978-998, 2017 Oct.
[Is] ISSN:1943-3670
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: Clinical and radiographic examinations are essential in establishing correct periodontal diagnoses as well as providing appropriate treatment options. Current radiographic examinations, however, do not provide adequate information regarding the severity of periodontal disease, presenting a need to investigate alternative methods. The aim of this best evidence consensus is to determine when cone-beam computed tomography (CBCT) imaging is appropriate for diagnostic inquiry in the management of inflammatory periodontitis. METHODS: Literature was systematically reviewed to answer three clinically relevant focused questions regarding the role of CBCT in the management of inflammatory periodontitis. 1) Clinical situation: In patients with periodontitis, what (if any) clinical situations/conditions exist where CBCT imaging improves diagnostic acumen and subsequent treatment recommendations compared with two-dimensional radiographic interpretation? 2) Intervention: Does CBCT imaging improve the accuracy of a diagnostic assessment and establishment of a prognosis in the analysis of furcation and/or intrabony defects? Is the execution of therapy improved and facilitated, or is it therapeutically challenged? 3) Outcomes: Does the use of CBCT imaging provide superior short-term or long-term clinical outcomes, more favorable patient-reported outcomes, or more consistent clinical treatment decisions affecting tooth prognosis (as measured by defect fill, improvements in bone anatomy, mobility patterns, and ultimate tooth survival)? An extensive literature search was performed using the MEDLINE database and the most respected journals in the field. RESULTS: An electronic database search identified 885 citations, and a manual search yielded an additional five citations. After screening of article titles and abstracts, studies were excluded if irrelevant to the topic of this systematic review. Of the remaining full-text articles, 74 were obtained and reviewed. Sixty-two articles not meeting inclusion criteria were further excluded. Twelve total references met the inclusion criteria to determine the role of CBCT in diagnosis and treatment of both intrabony and furcation defects. Intrabony and furcation defects were the two most commonly discussed bony defects when comparing efficacy of CBCT versus intraoral radiographs (IRs). After a review of the literature, while diagnostic aspects of intrabony and furcation defects can be improved via the use of CBCT, limited evidence supported the use of CBCT imaging improving the execution of therapy for both types of defects. There was also a lack of literature to support the use of CBCT imaging for superior short-term or long-term clinical outcomes. None of the literature reported patient-reported outcomes when CBCT imaging was used. CONCLUSIONS: Currently, limited evidence supports the utilization of CBCT for diagnosis of intrabony and furcation defects. Despite the fact that there is rapidly accruing literature on CBCT, there are still no current evidence-based guidelines on its necessity and use for periodontal treatment planning. In selective cases, however, limited field of view CBCT may be useful for periodontal disease diagnoses due to less radiation dosage to the patient, higher spatial resolution, and shorter volumes to be interpreted.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171002
[Lr] Last revision date:171002
[St] Status:In-Process
[do] DOI:10.1902/jop.2017.160505

  8 / 1068 MEDLINE  
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[PMID]: 28893049
[Au] Autor:Lohi HS; Nayak DG; Uppoor AS
[Ad] Address:Senior Lecturer, Department of Periodontics, PSM College of Dental Science and Research, Thrissur, Kerala, India.
[Ti] Title:Comparative Evaluation of the Efficacy of Bioactive Ceramic Composite Granules Alone and in Combination with Platelet Rich Fibrin in the Treatment of Mandibular Class II Furcation Defects: A Clinical and Radiographic Study.
[So] Source:J Clin Diagn Res;11(7):ZC76-ZC80, 2017 Jul.
[Is] ISSN:2249-782X
[Cp] Country of publication:India
[La] Language:eng
[Ab] Abstract:INTRODUCTION: Predictable closure of furcation defects with bone grafts, Guided Tissue Regeneration (GTR) and a combination of the two has remained an elusive goal so far. Hence, evaluation of biomimetic agents as candidate technologies for periodontal regeneration merit due consideration. In this study, Choukroun's Platelet Rich Fibrin (PRF), a second generation platelet concentrate, is combined with bone graft to examine if the addition enhances the therapeutic potential of bone graft in the management of Class II furcation defects. AIM: To evaluate and compare the clinical effectiveness of Bioactive Ceramic Composite Granules (BCCG) alone and in combination with PRF in the treatment of mandibular Class II furcation defects. MATERIALS AND METHODS: Twenty mandibular Class II furcation defects in 16 systemically healthy patients were randomly allocated to test and control groups. Test sites were treated with PRF and bone graft, while control sites were treated with BCCG alone. Soft tissue parameters (probing pocket depth and clinical attachment loss), hard tissue parameters (vertical and horizontal depth of furcation defects) and radiographic parameter (radiographic alveolar bone density) were measured at baseline and six months post surgery. Statistical analysis was performed using Wilcoxon signed rank test for intragroup comparison of parameters and Mann-Whitney U test for intergroup comparison. RESULTS: Statistically significant improvement was observed in the test group compared to the control group with respect to all the measured parameters. However, complete furcation closure was not observed at any of the treated sites. CONCLUSION: Adjunctive use of PRF with bone graft may be a more effective treatment modality in the management of mandibular Class II furcation defects when compared to bone graft alone.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1709
[Cu] Class update date: 170914
[Lr] Last revision date:170914
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.7860/JCDR/2017/23113.10255

  9 / 1068 MEDLINE  
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[PMID]: 28891547
[Au] Autor:Ozcan G; Sekerci AE
[Ad] Address:Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Erciyes University, 38039 Kayseri, Turkey.
[Ti] Title:Classification of alveolar bone destruction patterns on maxillary molars by using cone-beam computed tomography.
[So] Source:Niger J Clin Pract;20(8):1010-1019, 2017 Aug.
[Is] ISSN:1119-3077
[Cp] Country of publication:India
[La] Language:eng
[Ab] Abstract:OBJECTIVE: The defective diagnosis of alveolar structures is one of most serious handicaps when assessing available periodontal treatment options for the prevention of tooth loss. The aim of this research was to classify alveolar bone defects in the maxillary molar region which is a challenging area for dental implant applications. To our knowledge, this is the first study of periodontal bone defect prevalence by using cone-beam computed tomography (CBCT). MATERIALS AND METHODS: In this study, the remaining alveolar bone patterns of 669 maxillary molars of 243 patients with periodontal bone loss were investigated on four aspects and the furcation areas of teeth, and then they were classified into six main groups. Combined periodontal-endodontic lesions (CPELs) were also reported in another category. RESULTS: Following exclusion of 39 (5.8%) teeth with CPEL, the most common group was horizontal bone defects (71.4%) and the least seen group was three-walled vertical bone defects (1.9%) in all alveolar bone sides of teeth. Osseous crater was found at the rate of 6.7% on interdental alveolar bone. Dehiscence and fenestration were detected at rates of 2.7% and 3.3%, respectively. In the assessment of furcation areas, there was no furcation involvement in 61.4% of all teeth and the rate of Grade-II involvements was 26.2%. CONCLUSIONS: The most appropriate treatment option may be decided through accurate imaging of periodontal defect morphology. CBCT can provide comprehensive information about the remaining alveolar bone structures. In this way, the need for dental implant can be prevented in many cases and be replaced with a more conservative approach on the maxillary molar region.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1709
[Cu] Class update date: 170911
[Lr] Last revision date:170911
[St] Status:In-Data-Review
[do] DOI:10.4103/1119-3077.180074

  10 / 1068 MEDLINE  
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[PMID]: 28869397
[Au] Autor:Haas LF; Zimmermann GS; De Luca Canto G; Flores-Mir C; Corrêa M
[Ad] Address:1 Health Sciences Center, Federal University of Santa Catarina, Florianópolis, Brazil.
[Ti] Title:Precision of cone beam CT to assess periodontal bone defects: a systematic review and meta-analysis.
[So] Source:Dentomaxillofac Radiol;:20170084, 2017 10 27.
[Is] ISSN:0250-832X
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:OBJECTIVES: Evaluate the diagnostic validity of CBCT in measuring periodontal bone defects when compared with the reference standard (in situ measurement). METHODS: Studies in which the main objective was to evaluate the diagnostic validity of CBCT in measuring periodontal bone defects when compared with the reference standard were selected. Four databases were searched. The studies were selected by two independent reviewers. The methodology of selected studies was assessed using the 14-item Quality Assessment Tool for Diagnostic Accuracy Studies. The quality of evidence and strength of recommendation was assessed by The Grading of Recommendations Assessment Tool, Development and Evaluation. RESULTS: Using a selection process in two phases, 16 studies were identified and, in seven articles meta-analysis was performed. The results from these meta-analyses showed that no difference between the measurements of CBCT and in situ for alveolar bone loss, and demonstrated a concordance of 82.82% between CBCT and in situ for the classification of the degree of furcation involvement. CONCLUSIONS: Based on a moderate level of evidence, CBCT could be useful for furcation involvement periodontal cases, but it should only be used in cases where clinical evaluation and conventional radiographic imaging do not provide the information necessary for an adequate diagnosis and proper periodontal treatment planning.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1709
[Cu] Class update date: 171108
[Lr] Last revision date:171108
[St] Status:Publisher
[do] DOI:10.1259/dmfr.20170084


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