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[PMID]: 29111589
[Au] Autor:Gutiérrez-Grijalva EP; Angulo-Escalante MA; León-Félix J; Heredia JB
[Ad] Address:Centro de Investigación en Alimentación y Desarrollo, A.C., Carretera a Eldorado Km. 5.5, Col. Campo El Diez, Culiacán, Sinaloa 80110, México.
[Ti] Title:Effect of In Vitro Digestion on the Total Antioxidant Capacity and Phenolic Content of 3 Species of Oregano (Hedeoma patens, Lippia graveolens, Lippia palmeri).
[So] Source:J Food Sci;, 2017 Nov 07.
[Is] ISSN:1750-3841
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Oregano phenolic compounds have been studied for their anti-inflammatory properties. Nonetheless, after ingestion, the gastrointestinal environment can affect their antioxidant stability and thus their bioactive properties. To evaluate the effect of in vitro gastrointestinal (GI) digestion on the phenolic compounds of 3 species of oregano (Hedeoma patens, Lippia graveolens, and Lippia palmeri), the total reducing capacity, total flavonoid content, and antioxidant capacity were evaluated before and after in vitro GI digestion. In addition, the phenolic compounds of the 3 oregano species were identified and quantified by UPLC-PDA before and after in vitro GI digestion. It was shown that the reducing capacity, flavonoid content and antioxidant capacity were affected by the GI digestion process. Moreover, the phenolic compounds identified were apigenin-7-glucoside, scutellarein, luteolin, luteolin-7-glucoside, phloridzin and chlorogenic acid, and their levels were affected by the in vitro GI process. Our results showed that the phenolic compounds from these 3 species of oregano are affected by the in vitro digestion process, and this effect is largely attributable to pH changes. These changes can modify the bioavailability and further anti-inflammatory activity of oregano phenolics, and thus, further research is needed. PRACTICAL APPLICATION: Oregano is a rich source of polyphenols that have shown bioactive properties like anti-inflammatory potential. However, little is known of the gastrointestinal fate of oregano polyphenols which is imperative to fully understand its bioaccessibility. Our results are important to develop new administration strategies which could help protect the antioxidant and anti-inflammatory potential and bioaccessibility of such compounds.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171107
[Lr] Last revision date:171107
[St] Status:Publisher
[do] DOI:10.1111/1750-3841.13954

  2 / 13 MEDLINE  
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[PMID]: 27131433
[Au] Autor:Leyva-López N; Nair V; Bang WY; Cisneros-Zevallos L; Heredia JB
[Ad] Address:Centro de Investigación en Alimentación y Desarrollo A.C., Carretera a Eldorado km 5.5 Col. El Diez C.P. 80110, Culiacán, Sinaloa, México.
[Ti] Title:Protective role of terpenes and polyphenols from three species of Oregano (Lippia graveolens, Lippia palmeri and Hedeoma patens) on the suppression of lipopolysaccharide-induced inflammation in RAW 264.7 macrophage cells.
[So] Source:J Ethnopharmacol;187:302-12, 2016 Jul 01.
[Is] ISSN:1872-7573
[Cp] Country of publication:Ireland
[La] Language:eng
[Ab] Abstract:ETHNOPHARMACOLOGICAL RELEVANCE: Mexican oregano infusions have been traditionally used in México for the treatment of inflammation-related diseases, such as respiratory and digestive disorders, headaches and rheumatism, among others. Nevertheless, there is limited information regarding the phenolic compounds, terpenes and composition as well as biological activity of Mexican oregano. AIM OF THE STUDY: To determine the phenolic and terpene composition and to evaluate the anti-inflammatory potential of three species of Mexican oregano (Lippia graveolens (LG), Lippia palmeri (LP) and Hedeoma patens (HP)) in order to provide a scientific basis for their use. MATERIALS AND METHODS: We obtained methanol and chloroform extracts from dried oregano leaves of each species. We used LC-DAD-ESI-MS/MS and GC-MS to determine the phenolic and terpene profiles of the leaves, respectively. We evaluated anti-inflammatory potential by measuring the effect of Mexican oregano extracts on some pro-inflammatory mediators, such as nitric oxide (NO) and reactive oxygen species (ROS) using lipopolysaccharide(LPS)-stimulated RAW 264.7 macrophage cells and evaluating cyclooxygenase activity (COX-1, COX-2). RESULTS: Nine phenolic compounds (phenolic acids and flavonoids) and 22 terpenes (monoterpenes and sesquiterpenes) were detected in LG, LP and HP. We studied extracts from LG, LP and HP, and fractions from LG and LP in order to know their effect on some pro-inflammatory mediators. The phenolic and terpene extracts from LG, LP and HP exhibited significant inhibitory effect on ROS and NO production and mitochondrial activity in LPS-induced inflammation in RAW 264.7 macrophage cells. Nitric oxide production was also diminished by the terpene LG fraction LGF2 and the LP fractions LPF1, LPF2 and LPF3, confirming that both monoterpenes and sesquiterpenes are active compounds of oregano. Furthermore, the total extracts of LG, LP and HP exhibited non-selective inhibitions against the activity of the cyclooxygenases COX-1 and COX-2. CONCLUSIONS: Our results suggest that Lippia graveolens, Lippia palmeri and Hedeoma patens extracts have the potential to treat inflammatory diseases; their activity is mediated by polyphenols and terpenes. These findings support the claim for their traditional use in the treatment of inflammation-related diseases.
[Mh] MeSH terms primary: Anti-Inflammatory Agents/pharmacology
Hedeoma
Lippia
Polyphenols/pharmacology
Terpenes/pharmacology
[Mh] MeSH terms secundary: Animals
Cell Survival/drug effects
Inflammation/chemically induced
Inflammation/drug therapy
Lipopolysaccharides
Macrophages/drug effects
Mice
Nitric Oxide/metabolism
Plant Extracts/chemistry
Plant Leaves
Polyphenols/analysis
RAW 264.7 Cells
Reactive Oxygen Species/metabolism
Terpenes/analysis
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Anti-Inflammatory Agents); 0 (Lipopolysaccharides); 0 (Plant Extracts); 0 (Polyphenols); 0 (Reactive Oxygen Species); 0 (Terpenes); 31C4KY9ESH (Nitric Oxide)
[Em] Entry month:1703
[Cu] Class update date: 170302
[Lr] Last revision date:170302
[Js] Journal subset:IM
[Da] Date of entry for processing:160502
[St] Status:MEDLINE

  3 / 13 MEDLINE  
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[PMID]: 22951395
[Au] Autor:Coelho JP; Cristino AF; Matos PG; Rauter AP; Nobre BP; Mendes RL; Barroso JG; Mainar A; Urieta JS; Fareleira JM; Sovová H; Palavra AF
[Ad] Address:Centro de Investigação de Engenharia Química e Biotecnologia, Instituto Superior de Engenharia de Lisboa, Rua Conselheiro Emídio Navarro, 1, Lisboa 1959-007, Portugal. jcoelho@deq.isel.ipl.pt
[Ti] Title:Extraction of volatile oil from aromatic plants with supercritical carbon dioxide: experiments and modeling.
[So] Source:Molecules;17(9):10550-73, 2012 Sep 05.
[Is] ISSN:1420-3049
[Cp] Country of publication:Switzerland
[La] Language:eng
[Ab] Abstract:An overview of the studies carried out in our laboratories on supercritical fluid extraction (SFE) of volatile oils from seven aromatic plants: pennyroyal (Mentha pulegium L.), fennel seeds (Foeniculum vulgare Mill.), coriander (Coriandrum sativum L.), savory (Satureja fruticosa Béguinot), winter savory (Satureja montana L.), cotton lavender (Santolina chamaecyparisus) and thyme (Thymus vulgaris), is presented. A flow apparatus with a 1 L extractor and two 0.27 L separators was built to perform studies at temperatures ranging from 298 to 353 K and pressures up to 30.0 MPa. The best compromise between yield and composition compared with hydrodistillation (HD) was achieved selecting the optimum experimental conditions of extraction and fractionation. The major differences between HD and SFE oils is the presence of a small percentage of cuticular waxes and the relative amount of thymoquinone, an oxygenated monoterpene with important biological properties, which is present in the oils from thyme and winter savory. On the other hand, the modeling of our data on supercritical extraction of volatile oil from pennyroyal is discussed using Sovová's models. These models have been applied successfully to the other volatile oil extractions. Furthermore, other experimental studies involving supercritical CO(2) carried out in our laboratories are also mentioned.
[Mh] MeSH terms primary: Chromatography, Supercritical Fluid
Oils, Volatile/chemistry
Oils, Volatile/isolation & purification
Plant Oils/chemistry
Plant Oils/isolation & purification
[Mh] MeSH terms secundary: Carbon Dioxide
Coriandrum/chemistry
Foeniculum/chemistry
Hedeoma/chemistry
Lavandula/chemistry
Plant Extracts/chemistry
Satureja/chemistry
Thymus Plant/chemistry
Thymus Plant/metabolism
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; REVIEW
[Nm] Name of substance:0 (Oils, Volatile); 0 (Plant Extracts); 0 (Plant Oils); 142M471B3J (Carbon Dioxide)
[Em] Entry month:1302
[Cu] Class update date: 131121
[Lr] Last revision date:131121
[Js] Journal subset:IM
[Da] Date of entry for processing:120907
[St] Status:MEDLINE
[do] DOI:10.3390/molecules170910550

  4 / 13 MEDLINE  
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[PMID]: 21870634
[Au] Autor:Viveros-Valdez E; Rivas-Morales C; Oranday-Cardenas A; Verde-Star MJ; Carranza-Rosales P
[Ad] Address:Department of Chemistry, Faculty of Biological Sciences, Autonomous University of Nuevo Leon, San Nicolas de los Garza, Mexico.
[Ti] Title:Antimicrobial activity of Hedeoma drummondii against opportunistic pathogens.
[So] Source:Pak J Biol Sci;14(4):305-7, 2011 Feb 15.
[Is] ISSN:1028-8880
[Cp] Country of publication:Pakistan
[La] Language:eng
[Ab] Abstract:Hedeoma drummondii is a medicinal plant with diverse properties; however, validations of its medicinal uses are scarce. To evaluate its antimicrobial properties H. drummondii, was tested against opportunistic pathogens of medical importance. Antimicrobial tests were performed by the microdilution method in order to determine the Minimal Inhibitory Concentration (MIC) for each extract. Extracts of this plant showed relevant antimicrobial activity, results revealed that the hexanic extract has stronger activity and broader spectrum compared to acetone and methanol extracts. The activity of hexanic extract may be attributed mainly to the presence of the monoterpenes pulegone and menthol. In conclusion, the hexanic extract possess relevant antibacterial properties which suggests that H. drummondii have bioactive principles; these new data provide scientific support for the use of this plant in traditional medicine, particularly for gastrointestinal diseases.
[Mh] MeSH terms primary: Anti-Bacterial Agents/pharmacology
Hedeoma/chemistry
Plant Extracts/pharmacology
[Mh] MeSH terms secundary: Bacteria/drug effects
Hexanes/chemistry
Microbial Sensitivity Tests
Monoterpenes/pharmacology
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Anti-Bacterial Agents); 0 (Hexanes); 0 (Monoterpenes); 0 (Plant Extracts); 4LF2673R3G (pulegone)
[Em] Entry month:1109
[Cu] Class update date: 150311
[Lr] Last revision date:150311
[Js] Journal subset:IM
[Da] Date of entry for processing:110830
[St] Status:MEDLINE

  5 / 13 MEDLINE  
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[PMID]: 21385095
[Au] Autor:Dadé MM; Schinella GR; Fioravanti DE; Alfiotournier H
[Ad] Address:Facultad de Ciencias Médicas, Cátedra de Farmacología Básica, Universidad Nacional de La Plata, La Plata, Argentina.
[Ti] Title:Antioxidant and cytotoxic properties of an aqueous extract from the Argentinean plant Hedeoma multiflorum.
[So] Source:Pharm Biol;49(6):633-9, 2011 Jun.
[Is] ISSN:1744-5116
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:CONTEXT: Hedeoma multiflorum Benth. (Lamiaceae) is widely used in Argentinean popular medicine for digestive and anti-spasmodic purposes. However, knowledge about its pharmacological properties has been poorly investigated. OBJECTIVE: The antioxidant and cytotoxic properties of an aqueous extract from the plant were investigated for the first time. MATERIAL AND METHODS: Scavenging of stable free radicals of 2,2-azino-bis (3-ethylbenzo-thiazoline-6-sulfonic acid) diammonium salt (ABTS(+)) and 2,2-diphenyl-1-picryl hydrazyl (DPPH), reducing of ferric (III) iron of ferric reducing ability of plasma (FRAP) reagent, and inhibition of lipid peroxidation (LP) of human plasma and rat brain homogenates were assessed. Cytotoxicity was tested on human polymorphonuclear (PMN) cells using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay. Cytotoxicity was assessed by flow cytometric techniques. RESULTS: Extract scavenged ABTS(+) and DPPH (1.78 and 0.78 µmol Trolox equivalent/mg dry extract, respectively) and reduced FRAP reagent (0.66 µmol ascorbic acid equivalent/mg dry extract). LP of human plasma and rat brain was also inhibited in a dose-dependent way (inhibitory concentration 50%=27.0 and 86.0 µg/mL, respectively). Extract is rich in polyphenol compounds (0.96 ± 0.08 µmol equivalent caffeic acid/mg dry matter). Treatment of PMN decreased significantly the cell ability to reduce the MTT salt and increased the hypodiploid nuclei from 4 to 18% quantified using propidium iodide (PI). In the annexin V-Fluorescein isothiocyanate (annexin V-FITC) assay, 26% of treated cells were annexin V-FITC positive and PI negative. Using the 3,3'-dihexyloxacarbocyanine iodide uptake method, the negative fraction of cells was calculated as 29%. DISCUSSION AND CONCLUSION: H. multiflorum extract was found to have a significant antioxidant and pro-apoptotic activities, and a great potential as a source of healthy products.
[Mh] MeSH terms primary: Antioxidants/pharmacology
Cell Survival/drug effects
Hedeoma/chemistry
Plant Extracts/pharmacology
Plants, Medicinal/chemistry
[Mh] MeSH terms secundary: Animals
Antioxidants/chemistry
Apoptosis/drug effects
Argentina
Brain/drug effects
Brain/metabolism
Cells, Cultured
Dose-Response Relationship, Drug
Free Radicals/metabolism
Humans
Lipid Peroxidation/drug effects
Neutrophils/drug effects
Oxidation-Reduction/drug effects
Plant Extracts/chemistry
Plasma/metabolism
Rats
Water/chemistry
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Name of substance:0 (Antioxidants); 0 (Free Radicals); 0 (Plant Extracts); 059QF0KO0R (Water)
[Em] Entry month:1108
[Cu] Class update date: 131121
[Lr] Last revision date:131121
[Js] Journal subset:IM
[Da] Date of entry for processing:110310
[St] Status:MEDLINE
[do] DOI:10.3109/13880209.2010.526949

  6 / 13 MEDLINE  
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[PMID]: 20406139
[Au] Autor:Viveros-Valdez E; Rivas-Morales C; Oranday-Cárdenas A; Castro-Garza J; Carranza-Rosales P
[Ad] Address:Departamento de Química, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, México.
[Ti] Title:Antiproliferative effect from the Mexican poleo (Hedeoma drummondii).
[So] Source:J Med Food;13(3):740-2, 2010 Jun.
[Is] ISSN:1557-7600
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Hedeoma drummondii (poleo) has been used by Mexicans to prepare a tea for its pleasant taste. The methanolic extract, polar fractions, and major antioxidant compounds of the Mexican herbal tea obtained from aerial parts of H. drummondii ("poleo") showed antiproliferative effects against the cancer cell lines MCF-7 (human breast) and HeLa (human cervix). Phenolic acids isolated from poleo have significant antiproliferative effects with caffeic acid the most potent. This evidence suggests that herbal poleo tea may have chemopreventive properties.
[Mh] MeSH terms primary: Cell Proliferation/drug effects
Hedeoma/chemistry
Plant Extracts/pharmacology
[Mh] MeSH terms secundary: Antioxidants/analysis
Antioxidants/pharmacology
Caffeic Acids/analysis
Caffeic Acids/pharmacology
Cell Line, Tumor
HeLa Cells
Humans
Mexico
Plant Extracts/analysis
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Name of substance:0 (Antioxidants); 0 (Caffeic Acids); 0 (Plant Extracts); U2S3A33KVM (caffeic acid)
[Em] Entry month:1008
[Cu] Class update date: 121115
[Lr] Last revision date:121115
[Js] Journal subset:IM
[Da] Date of entry for processing:100422
[St] Status:MEDLINE
[do] DOI:10.1089/jmf.2009.0041

  7 / 13 MEDLINE  
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[PMID]: 19838732
[Au] Autor:Palacios SM; Bertoni A; Rossi Y; Santander R; Urzúa A
[Ad] Address:Laboratorio de Química Fina y Productos Naturales, Universidad Católica de Córdoba, Córdoba, Argentina. sarapalacios@ucc.edu.ar
[Ti] Title:Insecticidal activity of essential oils from native medicinal plants of Central Argentina against the house fly, Musca domestica (L.).
[So] Source:Parasitol Res;106(1):207-12, 2009 Dec.
[Is] ISSN:1432-1955
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:The insecticidal activity of nine essential oils (EOs) against the house fly (Musca domestica) was evaluated by placing flies in a screw-cap glass jar holding a piece of EO-treated cotton yarn. The dose necessary to kill 50% of flies (LC(50)) in 30 min was determined at 26 +/- 1 degrees C. The EOs showed LC(50) values ranging from 0.5 to 46.9 mg/dm(3). The EO from Minthostachys verticillata was the most potent insecticide (LC(50) = 0.5 mg/dm(3)) followed by EOs from Hedeoma multiflora (LC(50) = 1.3 mg/dm(3)) and Artemisia annua (LC(50) = 6.5 mg/dm(3)). The compositions of the nine EOs, obtained by hydrodistillation of medicinal herbs, were analyzed by gas chromatography/mass spectroscopy. These analyses showed that (4R)(+)-pulegone (69.70%), menthone (12.17%), and limonene (2.75%) were the principal components of M. verticillata EO. (4R)(+)-pulegone was also the main constituent (52.80%) of H. multiflora, while artemisia ketone (22.36%) and 1,8-cineole (16.67%) were the major constituents of A. annua EO. The terpene (4R)(+)-pulegone showed a lower toxicity (LC(50) = 1.7 mg/dm(3)) than M. verticillata or H. multiflora EOs. Dimethyl 2,2-dichlorovinyl phosphate, selected as a positive control, showed an LC(50) of 0.5 mg/dm(3). EOs from M. verticillata and H. multiflora show promise as natural insecticides against houseflies.
[Mh] MeSH terms primary: Artemisia annua/chemistry
Houseflies/drug effects
Insecticides/pharmacology
Lamiaceae/chemistry
Oils, Volatile/pharmacology
Plants, Medicinal/chemistry
[Mh] MeSH terms secundary: Animals
Argentina
Gas Chromatography-Mass Spectrometry
Insecticides/isolation & purification
Lethal Dose 50
Oils, Volatile/chemistry
Oils, Volatile/isolation & purification
Survival Analysis
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Name of substance:0 (Insecticides); 0 (Oils, Volatile)
[Em] Entry month:1003
[Cu] Class update date: 171007
[Lr] Last revision date:171007
[Js] Journal subset:IM
[Da] Date of entry for processing:091020
[St] Status:MEDLINE
[do] DOI:10.1007/s00436-009-1651-2

  8 / 13 MEDLINE  
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[PMID]: 18669018
[Au] Autor:Viveros-Valdez E; Rivas-Morales C; Carranza-Rosales P; Mendoza S; Schmeda-Hirschmann G
[Ad] Address:Departamento de Química, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Mexico.
[Ti] Title:Free radical scavengers from the Mexican herbal tea "poleo" (Hedeoma drummondii).
[So] Source:Z Naturforsch C;63(5-6):341-6, 2008 May-Jun.
[Is] ISSN:0939-5075
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:The aerial parts of the Lamiaceae Hedeoma drummondii (Benth.) are used in Mexico to prepare a herbal tea and by North American Amerindians as a spice. The methanolic extract of the aerial parts exhibited a strong antioxidant effect measured by the scavenging of the free diphenyl picrylhydrazyl (DPPH) radical. Assay-guided fractionation of the crude methanolic extract allowed the identification of three major active constituents, chlorogenic, caffeic and rosmarinic acid, as well as sideritoflavone derivatives and simple phenolics. The TEAC, FRAP, total phenolic and flavonoid content were determined. The high content of caffeic acid and rosmarinic acid relates to the antioxidant activity of H. drummondii.
[Mh] MeSH terms primary: Free Radical Scavengers/isolation & purification
Free Radical Scavengers/pharmacology
Hedeoma/chemistry
[Mh] MeSH terms secundary: Beverages/analysis
Flavonoids/chemistry
Flavonoids/isolation & purification
Flavonoids/pharmacology
Phenols/chemistry
Phenols/isolation & purification
Phenols/pharmacology
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Name of substance:0 (Flavonoids); 0 (Free Radical Scavengers); 0 (Phenols)
[Em] Entry month:0808
[Cu] Class update date: 091104
[Lr] Last revision date:091104
[Js] Journal subset:IM
[Da] Date of entry for processing:080802
[St] Status:MEDLINE

  9 / 13 MEDLINE  
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[PMID]: 18206775
[Au] Autor:Bluma RV; Etcheverry MG
[Ad] Address:Departamento de Microbiología e Inmunología, Facultad de Ciencias Exactas Físico Químicas y Naturales, Universidad Nacional de Río Cuarto, Ruta Nacional N 36 Km 601, Río Cuarto (5800), Córdoba, Argentina.
[Ti] Title:Application of essential oils in maize grain: impact on Aspergillus section Flavi growth parameters and aflatoxin accumulation.
[So] Source:Food Microbiol;25(2):324-34, 2008 Apr.
[Is] ISSN:1095-9998
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:The antifungal activity of Pimpinella anisum L. (anise), Pëumus boldus Mol (boldus), Hedeoma multiflora Benth (mountain thyme), Syzygium aromaticum L. (clove), and Lippia turbinate var. integrifolia (griseb) (poleo) essential oils (EOs) against Aspergillus section Flavi was evaluated in sterile maize grain under different water activity (a(w)) condition (0.982, 0.955, and 0.90). The effect of EOs added to maize grains on growth rate, lag phase, and aflatoxin B(1) (AFB(1)) accumulation of Aspergillus section Flavi were evaluated at different water activity conditions. The five EOs analyzed have been shown to influence lag phase and growth rate. Their efficacy depended mainly on the essential oil concentrations and substrate water activity conditions. All EOs showed significant impact on AFB(1) accumulation. This effect was closely dependent on the water activity, concentration, and incubation periods. Important reduction of AFB(1) accumulation was observed in the majority of EO treatments at 11 days of incubation. Boldus, poleo, and mountain thyme EO completely inhibited AFB(1) at 2000 and 3000 microg g(-1). Inhibition of AFB(1) accumulation was also observed when aflatoxigenic isolates grew with different concentration of EOs during 35 days.
[Mh] MeSH terms primary: Aflatoxin B1/biosynthesis
Aspergillus flavus/drug effects
Food Contamination/analysis
Oils, Volatile/pharmacology
Water/metabolism
Zea mays/microbiology
[Mh] MeSH terms secundary: Aspergillus flavus/growth & development
Aspergillus flavus/metabolism
Dose-Response Relationship, Drug
Food Contamination/prevention & control
Food Preservation/methods
Food Preservatives/pharmacology
Kinetics
Time Factors
Zea mays/chemistry
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Name of substance:0 (Food Preservatives); 0 (Oils, Volatile); 059QF0KO0R (Water); 9N2N2Y55MH (Aflatoxin B1)
[Em] Entry month:0802
[Cu] Class update date: 131121
[Lr] Last revision date:131121
[Js] Journal subset:IM
[Da] Date of entry for processing:080122
[St] Status:MEDLINE
[do] DOI:10.1016/j.fm.2007.10.004

  10 / 13 MEDLINE  
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[PMID]: 16373019
[Au] Autor:López-Briz E; Garrigues-Gil V
[Ti] Title:Hepatitis por hierbas chinas. [Hepatitis due to Chinese herbs].
[So] Source:Gastroenterol Hepatol;28(10):656, 2005 Dec.
[Is] ISSN:0210-5705
[Cp] Country of publication:Spain
[La] Language:spa
[Mh] MeSH terms primary: Chemical and Drug Induced Liver Injury/etiology
Drugs, Chinese Herbal/adverse effects
Hedeoma/adverse effects
Mentha pulegium/adverse effects
[Mh] MeSH terms secundary: Beverages/adverse effects
Beverages/analysis
Biotransformation
Humans
Plant Oils/adverse effects
Plant Oils/chemistry
Solubility
[Pt] Publication type:LETTER; COMMENT
[Nm] Name of substance:0 (Drugs, Chinese Herbal); 0 (Plant Oils)
[Em] Entry month:0605
[Cu] Class update date: 161124
[Lr] Last revision date:161124
[Js] Journal subset:IM
[Da] Date of entry for processing:051224
[St] Status:MEDLINE


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