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[PMID]: 29509294
[Au] Autor:Giovanelli S; De Leo M; Cervelli C; Ruffoni B; Ciccarelli D; Pistelli L
[Ad] Address:Dipartimento di Farmacia, Università di Pisa, via Bonanno 6, 56126, Pisa, Italy.
[Ti] Title:Essential oil composition and volatile profile of seven Helichrysum species grown in Italy.
[So] Source:Chem Biodivers;, 2018 Mar 06.
[Is] ISSN:1612-1880
[Cp] Country of publication:Switzerland
[La] Language:eng
[Ab] Abstract:Helichrysum genus consists of about 600 species widespread throughout the world, especially in South Africa and in the Mediterranean area. In this study the aroma profile (HS-SPME) and the EO compositions of seven Helichrysum species (H. cymosum, H. odoratissimum, H. petiolare, H. fontanesii, H. saxatile, H. sanguineum and H. tenax) were evaluated. All the plants were grown in Italy under the same growth conditions. The volatile constituents, particularly monoterpenes, depended by the plant's genotype and ecological adaptation. This study represents the first headspace evaluation on the selected plants and the results evidenced that monoterpenes represented the main class of constituents in five of the seven species analyzed (from 59.2% to 95.0%). The higher content in sesquiterpene hydrocarbons was observed in the Mediterranean species of H. sanguineum (68.0%). Only H. saxatile showed relative similar abundance of monoterpenes and sesquiterpene hydrocarbons. The essential oil composition of the majority of examined species are characterized by high percentage of sesquiterpenes (expecially ß-caryophyllene and δ-cadinene) ranging from 51.3% to 92.0%, except for H. cymosum, H. tenax and H. sanguineum-leaves where monoterpenes predominated (from 51.7% to 74.7%). This article is protected by copyright. All rights reserved.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180306
[Lr] Last revision date:180306
[St] Status:Publisher
[do] DOI:10.1002/cbdv.201700545

  2 / 242 MEDLINE  
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[PMID]: 29438342
[Au] Autor:Babota M; Mocan A; Vlase L; Crișan O; Ielciu I; Gheldiu AM; Vodnar DC; Crișan G; Paltinean R
[Ad] Address:Department of Pharmaceutical Botany, "Iuliu Hațieganu" University of Medicine and Pharmacy, 400337 Cluj-Napoca, Romania. babotamihai95@gmail.com.
[Ti] Title:Phytochemical Analysis, Antioxidant and Antimicrobial Activities of Helichrysum arenarium (L.) Moench. and Antennaria dioica (L.) Gaertn. Flowers.
[So] Source:Molecules;23(2), 2018 Feb 13.
[Is] ISSN:1420-3049
[Cp] Country of publication:Switzerland
[La] Language:eng
[Ab] Abstract:(L.) Gaertn. and (L.) Moench. are two species of the Asteraceae family, known in Romanian traditional medicine for their diuretic, choleretic, and anti-inflammatory properties. The aim of the present study was to evaluate the phenolic and sterolic composition of flowers from the two species and to assess their antioxidant, antibacterial and antifungal properties. LC-MS analyses were performed on methanolic, ethanolic and 70% ethanolic extracts, before and after acid hydrolysis, and revealed high amounts of polyphenols. Chlorogenic acid was found as the main compound for the flowers of (502.70 ± 25.11 mg/100 g d.w.), while quercitrin was dominant in (424.28 ± 21.21 mg/100 g d.w.) in 70% / ethanolic extracts before hydrolysis. Antioxidant capacity assays showed an important antioxidant potential, which can be correlated with the determined polyphenolic compounds, showing the 70% / ethanolic extracts of the two species as being the most effective antioxidant samples for the DPPH assay. Antibacterial and antifungal assays confirm a modest biological potential for the same extract of both species. Results obtained in the present study bring important data and offer scientific evidence on the chemical composition and on the biological activities of the flowers belonging to the two species.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180213
[Lr] Last revision date:180213
[St] Status:In-Process

  3 / 242 MEDLINE  
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[PMID]: 29124622
[Au] Autor:Memariani Z; Moeini R; Hamedi SS; Gorji N; Mozaffarpur SA
[Ad] Address:Traditional Medicine and History of Medical Sciences Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Islamic Republic of Iran.
[Ti] Title:Medicinal plants with antithrombotic property in Persian medicine: a mechanistic review.
[So] Source:J Thromb Thrombolysis;, 2017 Nov 09.
[Is] ISSN:1573-742X
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:Thrombosis is one of the major causes of morbidity and mortality in a wide range of vessels diseases. Due to the high prevalence of thromboembolic disorders investigations are being carried out on new antithrombotic agents with limited adverse side effects in which herbal medicines are considered as alternative remedies. Persian medicine (PM) as a traditional medicine has a good potential for pharmacotherapy based on its own principles and development of drugs via investigating PM literature. In PM manuscripts there are some concepts that express the management of blood clots and antithrombotic properties. This study reviewed the pharmacological effects of medicinal plants mentioned in PM literature for blood clot management in light of current knowledge. Plants mentioned in PM for management of blood clot belong to 12 families in which Apiaceae, Lamiaceae and Compositae were the most repeated ones. Among the proposed plants Allium sativum, Rosmarinus officinalis, Boswellia serrata, Sesamum indicum, Matricaria chamomilla and Carthamus tinctorius have been the most researched plants in modern antithrombotic studies while for some plants such as Helichrysum stoechas, Dracocephalum kotschi, Carum carvi, Bunium persicum and Lagoecia cuminoides no evidence could be found. One of the interesting notes in clot management in PM texts was introducing the target organ for some of the recommended herbs like Carum carvi and Bunium persicum for dissolving blood clot in stomach and Commiphora mukul for thrombosed hemorrhoid. It seems review of PM recommendations can help to design future researches for antithrombotic drugs discovering with more effectiveness and safety.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1711
[Cu] Class update date: 171110
[Lr] Last revision date:171110
[St] Status:Publisher
[do] DOI:10.1007/s11239-017-1580-3

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[PMID]: 29098868
[Au] Autor:Benelli G; Pavela R; Rakotosaona R; Randrianarivo E; Nicoletti M; Maggi F
[Ad] Address:a Department of Agriculture, Food and Environment , University of Pisa , Pisa , Italy.
[Ti] Title:Chemical composition and insecticidal activity of the essential oil from Helichrysum faradifani endemic to Madagascar.
[So] Source:Nat Prod Res;:1-9, 2017 Nov 03.
[Is] ISSN:1478-6427
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Helichrysum faradifani (Asteraceae) is a perennial shrub growing in rocky and sandy places of Madagascar. The plant is used in the Malagasy traditional medicine as a wound-healing agent, disinfectant and for the treatment of syphilis, diarrhea, cough and headache. In the present work, we analysed the chemical composition of the essential oil distilled from the aerial parts of H. faradifani by GC-MS and evaluated its insecticidal activity against 2nd, 3rd and 4th instar larvae of the lymphatic filariasis vector Culex quinquefasciatus by acute toxicity assays. The most sensitive were 2nd instar (LC = 85.7 µL L ) larvae. For the 3rd and 4th instar larvae, the estimated LC were 156.8 and 134.1 µL L , respectively. Monoterpene hydrocarbons (51.6%) were the major fraction of the essential oil, with the bicyclic α-fenchene (35.6%) as the predominant component. Sesquiterpene hydrocarbons (34.0%) were the second major group characterising the oil, with γ-curcumene (17.7%) as the most abundant component.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:Publisher
[do] DOI:10.1080/14786419.2017.1396590

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[PMID]: 28941742
[Au] Autor:Pollastro F; De Petrocellis L; Schiano-Moriello A; Chianese G; Heyman H; Appendino G; Taglialatela-Scafati O
[Ad] Address:Dipartimento di Scienze del Farmaco, Università del Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
[Ti] Title:Amorfrutin-type phytocannabinoids from Helichrysum umbraculigerum.
[So] Source:Fitoterapia;123:13-17, 2017 Nov.
[Is] ISSN:1873-6971
[Cp] Country of publication:Netherlands
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1709
[Cu] Class update date: 171115
[Lr] Last revision date:171115
[St] Status:In-Data-Review

  6 / 242 MEDLINE  
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[PMID]: 28926642
[Au] Autor:Courtney Mustaphi CJ; Gajewski K; Marchant R; Rosqvist G
[Ad] Address:York Institute for Tropical Ecosystems, Environment Department, Wentworth Way, University of York, York, United Kingdom.
[Ti] Title:A late Holocene pollen record from proglacial Oblong Tarn, Mount Kenya.
[So] Source:PLoS One;12(9):e0184925, 2017.
[Is] ISSN:1932-6203
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:High-elevation ecosystems, such as those on Mount Kenya are undergoing significant changes, with accelerated glacial ice losses over the twentieth century creating new space for alpine plants to establish. These ecosystems respond rapidly to climatic variability and within decades of glacial retreat, Afroalpine pioneering taxa stabilize barren land and facilitate soil development, promoting complex patches of alpine vegetation. Periglacial lake sediment records can be used to examine centennial and millennial scale variations in alpine and montane vegetation compositions. Here we present a 5300-year composite pollen record from an alpine tarn (4370 m asl) in the Hausberg Valley of Mount Kenya. Overall, the record shows little apparent variation in the pollen assemblage through time with abundant montane forest taxa derived and transported from mid elevations, notably high abundances of aerophilous Podocarpus pollen. Afroalpine taxa included Alchemilla, Helichrysum and Dendrosenecio-type, reflecting local vegetation cover. Pollen from the ericaceous zone was present throughout the record and Poaceae percentages were high, similar to other high elevation pollen records from eastern Africa. The Oblong Tarn record pollen assemblage composition and abundances of Podocarpus and Poaceae since the late Holocene (~4000 cal yr BP-present) are similar to pollen records from mid-to-high elevation sites of nearby high mountains such as Mount Elgon and Kilimanjaro. These results suggest a significant amount of uphill pollen transport with only minor apparent variation in local taxa. Slight decreasing trends in alpine and ericaceous taxonomic groups show a long-term response to global late Holocene cooling and a step decrease in rate of change estimated from the pollen assemblages at 3100 cal yr BP in response to regional hydroclimatic variability. Changes in the principal component axis scores of the pollen assemblage were coherent with an independent mid-elevation temperature reconstruction, which supported the strong influence of uphill pollen transport from montane forest vegetation and association between temperatures and montane vegetation dynamics. Pollen accumulation rates showed some variability related to minerogenic sediment input to the lake. The Oblong Tarn pollen record provides an indication of long term vegetation change atop Mount Kenya showing some decreases in local alpine and ericaceous taxa from 5300-3100 cal yr BP and minor centennial-scale variability of montane taxa from mid elevation forests. The record highlights potentials, challenges and opportunities for the use of proglacial lacustrine sediment to examine vegetation change on prominent mountain massifs.
[Mh] MeSH terms primary: Pollen/anatomy & histology
[Mh] MeSH terms secundary: Climate
Ecosystem
Fossils/history
Geologic Sediments/analysis
History, Ancient
Kenya
Pollen/chemistry
Trees/growth & development
Trees/physiology
[Pt] Publication type:HISTORICAL ARTICLE; JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171020
[Lr] Last revision date:171020
[Js] Journal subset:IM
[Da] Date of entry for processing:170920
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0184925

  7 / 242 MEDLINE  
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[PMID]: 28900733
[Au] Autor:Mammino L
[Ad] Address:Department of Chemistry, University of Venda, Thohoyandou, South Africa. sasdestria@yahoo.com.
[Ti] Title:Complexes of arzanol with a Cu ion: a DFT study.
[So] Source:J Mol Model;23(10):276, 2017 Sep 12.
[Is] ISSN:0948-5023
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:Arzanol (C H O ) is a naturally occurring acylphloroglucinol largely responsible for the anti-inflammatory, anti-oxidant, antibiotic and antiviral activities of Helichrysum italicum. Like all acylphloroglucinols, the molecule contains a carboxylic substituent (-COR group); for arzanol, this is a -COCH group. The molecule is further characterized by the presence of an α-pyrone ring bonded in meta to -COR through a methylene bridge, and of a prenyl chain bonded to the other meta position. The molecule can form up to three intramolecular hydrogen bonds (IHB) simultaneously, and their presence and patterns are the major stabilizing factors. This work considers complexes of representative conformers of arzanol with a Cu ion, taking into account the different possibilities for the binding of the Cu ion to the electron-density rich sites of the molecule and including simultaneous coordination to two geometrically suitable sites. Calculations were performed at the DFT/B3LYP level, using the 6-31+G(d,p) basis set for the C, O and H atoms and the LANL2DZ pseudopotential for the Cu ion. Interaction energies show preference for simultaneous binding of Cu to two sites. Simultaneous binding to the O of a phenol OH neighboring the prenyl chain and to the π bond of the prenyl chain appears to be the most favorable option, followed by simultaneous binding to the sp O of the α-pyrone ring and the O of the phenol OH ortho to -COR on the side of the α-pyrone ring. The charge of the Cu ion is reduced to +1 or slightly less in the complexes, which is consistent with the molecules' antioxidant (reducing) ability. Graphical abstract The copper ion prefers to attach to two sites of the arzanol molecule simultaneously. The arzanol molecule reduces the charge of the copper ion from +2 to +1 by transferring an electron to it; it becomes a radical molecular cation. The distribution of the unpaired electron in the molecule (as highlighted by the spin density maps) depends on the site/s to which the Cu ion binds and on the molecule's conformer.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1709
[Cu] Class update date: 170916
[Lr] Last revision date:170916
[St] Status:In-Data-Review
[do] DOI:10.1007/s00894-017-3443-4

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[PMID]: 28876249
[Au] Autor:Monteiro CM; Calheiros CSC; Palha P; Castro PML
[Ad] Address:CBQF - Centro de Biotecnologia e Química Fina - Laboratório Associado, Escola Superior de Biotecnologia, Rua Arquiteto Lobão Vital, Universidade Católica Portuguesa, Apartado 2511, 4202-401 Porto, Portugal E-mail: plcastro@porto.ucp.pt.
[Ti] Title:Growing substrates for aromatic plant species in green roofs and water runoff quality: pilot experiments in a Mediterranean climate.
[So] Source:Water Sci Technol;76(5):1081-1089, 2017 Sep.
[Is] ISSN:0273-1223
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Green roof technology has evolved in recent years as a potential solution to promote vegetation in urban areas. Green roof studies for Mediterranean climates, where extended drought periods in summer contrast with cold and rainy periods in winter, are still scarce. The present research study assesses the use of substrates with different compositions for the growth of six aromatic plant species - Lavandula dentata, Pelargonium odoratissimum, Helichrysum italicum, Satureja montana, Thymus caespititius and T. pseudolanuginosus, during a 2-year period, and the monitoring of water runoff quality. Growing substrates encompassed expanded clay and granulated cork, in combination with organic matter and crushed eggshell. These combinations were adequate for the establishment of all aromatic plants, allowing their propagation in the extensive system located on the 5th storey. The substrate composed of 70% expanded clay and 30% organic matter was the most suitable, and crushed eggshell incorporation improved the initial plant establishment. Water runoff quality parameters - turbidity, pH, conductivity, NH , NO , PO and chemical oxygen demand - showed that it could be reused for non-potable uses in buildings. The present study shows that selected aromatic plant species could be successfully used in green roofs in a Mediterranean climate.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1709
[Cu] Class update date: 170906
[Lr] Last revision date:170906
[St] Status:In-Data-Review
[do] DOI:10.2166/wst.2017.276

  9 / 242 MEDLINE  
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[PMID]: 28836041
[Au] Autor:Detsch F; Otte I; Appelhans T; Nauss T
[Ad] Address:Environmental Informatics, Faculty of Geography, Philipps-Universität Marburg, Deutschhausstr. 12, 35032, Marburg, Germany. florian.detsch@staff.uni-marburg.de.
[Ti] Title:A glimpse at short-term controls of evapotranspiration along the southern slopes of Kilimanjaro.
[So] Source:Environ Monit Assess;189(9):465, 2017 Aug 23.
[Is] ISSN:1573-2959
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:Future climate characteristics of the southern Kilimanjaro region, Tanzania, are mainly determined by local land-use and global climate change. Reinforcing increasing dryness throughout the twentieth century, ongoing land transformation processes emphasize the need for a proper understanding of the regional-scale water budget and possible implications on related ecosystem functioning and services. Here, we present an analysis of scintillometer-based evapotranspiration (ET) covering seven distinct habitat types across a massive climate gradient from the colline savanna woodlands to the upper-mountain Helichrysum zone (940 to 3960 m.a.s.l.). Random forest-based mean variable importance indicates an outstanding significance of net radiation (R ) on the observed ET across all elevation levels. Accordingly, topography and frequent cloud/fog events have a dampening effect at high elevations, whereas no such constraints affect the energy and moisture-rich submontane coffee/grassland level. By contrast, long-term moisture availability is likely to impose restrictions upon evapotranspirative net water loss in savanna, which particularly applies to the pronounced dry season. At plot scale, ET can thereby be approximated reasonably using R , soil heat flux, and to a lesser degree, vapor pressure deficit and rainfall as predictor variables (R 0.59 to 1.00). While multivariate regression based on pooled meteorological data from all plots proves itself useful for predicting hourly ET rates across a broader range of ecosystems (R = 0.71), additional gains in explained variance can be achieved when vegetation characteristics as seen from the NDVI are considered (R = 0.87). To sum up, our results indicate that valuable insights into land cover-specific ET dynamics, including underlying drivers, may be derived even from explicitly short-term measurements in an ecologically highly diverse landscape.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1708
[Cu] Class update date: 170924
[Lr] Last revision date:170924
[St] Status:In-Process
[do] DOI:10.1007/s10661-017-6179-9

  10 / 242 MEDLINE  
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[PMID]: 28787672
[Au] Autor:Pereira CG; Barreira L; Bijttebier S; Pieters L; Neves V; Rodrigues MJ; Rivas R; Varela J; Custódio L
[Ad] Address:Centre of Marine Sciences, University of Algarve, Faculty of Sciences and Technology, Ed. 7, Campus of Gambelas, 8005-139, Faro, Portugal. Electronic address: cagpereira@ualg.pt.
[Ti] Title:Chemical profiling of infusions and decoctions of Helichrysum italicum subsp. picardii by UHPLC-PDA-MS and in vitro biological activities comparatively with green tea (Camellia sinensis) and rooibos tisane (Aspalathus linearis).
[So] Source:J Pharm Biomed Anal;145:593-603, 2017 Oct 25.
[Is] ISSN:1873-264X
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Several medicinal plants are currently used by the food industry as functional additives, for example botanical extracts in herbal drinks. Moreover, the scientific community has recently begun focusing on halophytes as sources of functional beverages. Helichrysum italicum subsp. picardii (everlasting) is an aromatic halophyte common in southern Europe frequently used as spice and in traditional medicine. In this context, this work explored for the first time H. italicum subsp. picardii as a potential source of innovative herbal beverages with potential health promoting properties. For that purpose, infusions and decoctions were prepared from roots, vegetative aerial-organs (stems and leaves) and flowers and evaluated for in vitro antioxidant and anti-diabetic activities. Samples were also assessed for toxicity in different mammalian cell lines and chemically characterized by spectrophotometric methods and ultra-high performance liquid chromatography-photodiode array-mass-spectrometry (UHPLC-PDA-MS). Results were expressed relating to 'a cup-of-tea' and compared with those obtained with green tea (Camellia sinensis) and rooibos tisane (Aspalathus linearis). Tisanes from the everlasting's above-ground organs, particularly flowers, have high polyphenolic content and several phenolics were identified; the main compounds were chlorogenic and quinic acids, dicaffeoylquinic-acid isomers and gnaphaliin-A. The antioxidant activity of beverages from the everlasting's above-ground organs matched or surpassed that of green tea and rooibos. Its anti-diabetic activity was moderate and toxicity low. Overall, our results suggest that the everlasting is a potential source of innovative and functional herbal beverages.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1708
[Cu] Class update date: 170906
[Lr] Last revision date:170906
[St] Status:In-Process


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