Database : MEDLINE
Search on : history [Words]
References found : 737307 [refine]
Displaying: 1 .. 10   in format [Detailed]

page 1 of 73731 go to page                         

  1 / 737307 MEDLINE  
              next record last record
select
to print
Photocopy
Full text

[PMID]: 24291546
[Au] Autor:Gosalbez M; Hupe MC; Lokeshwar SD; Yates TJ; Shields J; Veerapen MK; Merseburger AS; Rosser CJ; Soloway MS; Lokeshwar VB
[Ad] Address:Department of Urology, University of Miami Miller School of Medicine, Miami, Florida....
[Ti] Title:Differential Expression of SDF-1 Isoforms in Bladder Cancer.
[So] Source:J Urol;191(6):1899-905, 2014 Jun.
[Is] ISSN:1527-3792
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:PURPOSE: SDF-1 is a ligand of the chemokine receptors CXCR4 and 7. The 6 known SDF-1 isoforms are generated by alternative mRNA splicing. While SDF-1 expression has been detected in various malignancies, only few groups have reported differential expression of SDF-1 isoforms and its clinical significance. We evaluated the expression of 3 SDF-1 isoforms (α, ß and γ) in bladder cancer. MATERIALS AND METHODS: Using quantitative polymerase chain reaction we measured SDF-1α, ß and γ mRNA levels in 25 normal and 44 bladder cancer tissues, and in 210 urine specimens (28 normal, 74 benign, 57 bladder cancer, 35 bladder cancer history, 8 other cancer history and 8 other cancer) from consecutive patients. Levels were correlated with clinical outcome. RESULTS: Of the SDF-1 isoforms only SDF-1ß mRNA was significantly over expressed 2.5-fold to sixfold in bladder cancer compared to normal bladder tissues. SDF-1α was expressed in bladder tissues but SDF-1γ was undetectable. On multivariate analysis SDF-1ß was an independent predictor of metastasis and disease specific mortality (p = 0.017 and 0.043, respectively). In exfoliated urothelial cells only SDF-1ß mRNA levels were differentially expressed with 91.2% sensitivity and 73.8% specificity for detecting bladder cancer. In patients with a bladder cancer history increased SDF-1ß levels indicated a 4.3-fold increased risk of recurrence within 6 months (p = 0.0001). CONCLUSIONS: SDF-1 isoforms are differentially expressed in bladder tissues and exfoliated urothelial cells. SDF-1ß mRNA levels in bladder cancer tissues predict a poor prognosis. Furthermore, SDF-1ß mRNA levels in exfoliated cells detect bladder cancer with high sensitivity and they are a potential predictor of future recurrence.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1410
[Js] Journal subset:AIM; IM
[St] Status:In-Data-Review

  2 / 737307 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
PubMed Central Full text
Full text

[PMID]: 25276304
[Au] Autor:Dattilo G; Anfuso C; Casale M; Giugno V; Camarda L; Laganà N; Di Bella G
[Ad] Address:Giuseppe Dattilo, Matteo Casale, Vincenza Giugno, Lorenzo Camarda, Natascia Laganà, Gianluca Di Bella, Department of Clinical and Experimental Medicine, Section of Cardiology, University of Messina, 98125 Messina, Italy....
[Ti] Title:Calcific left atrium: A rare consequence of endocarditis.
[So] Source:World J Cardiol;6(9):1038-40, 2014 Sep 26.
[Is] ISSN:1949-8462
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Usually, cardiac calcifications are observed in aortic and mitral valves, atrio-ventricular plane, mitral annulus, coronary arteries, pericaridium (usually causing constrictive pericarditis) and cardiac masses. Calcifications of atrial walls are unusual findings that can be identified only using imaging with high spatial resolution, such as cardiac magnetic resonance and computed tomography. We report a case of a 43-year-old patient with no history of heart disease that underwent cardiac evaluation for mild dyspnoea. The echocardiogram showed a calcific aortic valve and a hyper-echogenic lesion located in atrio-ventricular plane. The patient was submitted to cardiac magnetic resonance and to computed tomography imaging to better characterize the localization of mass. The clinical features and location of calcified lesion suggest an infective aetiology causing an endocarditis involving the aortic valve, atrio-ventricular plane and left atrium. Although we haven't data to support a definite and clear diagnosis, the clinical features and location of the calcified lesion suggest an infective aetiology causing an endocarditis involving the aortic valve, atrio-ventricular plane and left atrium. The patient was followed for 12 mo both clinically and by electrocardiogram and echocardiography without worsening of clinical, electrocardiographic and echocardiographic data. Cardiac magnetic resonance imaging and computed tomography are ideal methods for identifying and following over time patients with calcific degeneration in the heart.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1410
[Cu] Class update date: 141004
[Lr] Last revision date:141004
[Da] Date of entry for processing:141003
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.4330/wjc.v6.i9.1038

  3 / 737307 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
PubMed Central Full text
Full text

[PMID]: 25276325
[Au] Autor:Mirimanoff RO; Ozsahin M; Thariat J; Ozyar E; Schick U; Pehlivan B; Krengli M; Pellanda AF; Vees H; Cai L; Scandolaro L; Belkacemi Y; Villà S; Igdem S; Lutsyk M; Miller RC
[Ad] Address:Department of Radiation Oncology, University of Lausanne Medical Center , Lausanne, Switzerland....
[Ti] Title:History of the rare cancer network and past research.
[So] Source:Rare Tumors;6(3):5462, 2014 Jul 30.
[Is] ISSN:2036-3605
[Cp] Country of publication:Italy
[La] Language:eng
[Ab] Abstract:Approximately, twenty years ago, the Rare Cancer Network (RCN) was formed in Lausanne, Switzerland, to support the study of rare malignancies. The RCN has grown over the years and now includes 130 investigators from twenty-four nations on six continents. The network held its first international symposium in Nice, France, on March 21-22, 2014. The proceedings of that meeting are presented in two companion papers. This manuscript reviews the history of the growth of the RCN and contains the abstracts of fourteen oral presentations made at the meeting of prior RCN studies. From 1993 to 2014, 74 RCN studies have been initiated, of which 54 were completed, 10 are in progress or under analysis, and 9 were stopped due to poor accrual. Forty-four peer reviewed publications have been written on behalf of the RCN.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1410
[Cu] Class update date: 141004
[Lr] Last revision date:141004
[Da] Date of entry for processing:141003
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.4081/rt.2014.5462

  4 / 737307 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
PubMed Central Full text
Full text

[PMID]: 25276390
[Au] Autor:Liao Y; Chen KH; Huang GY; Song W
[Ad] Address:Department of Cardiology, Longyan First Hospital, Fujian Medical University, Longyan 364000, China....
[Ti] Title:Pulmonary arteriovenous malformations presenting as refractory heart failure.
[So] Source:J Thorac Dis;6(9):E169-72, 2014 Sep.
[Is] ISSN:2072-1439
[Cp] Country of publication:China
[La] Language:eng
[Ab] Abstract:A 22-year-old young man with a history of idiopathic dilated cardiomyopathy (IDC) was admitted to our hospital due to difficult-to-control heart failure. A thoracic X-ray showed multiple nodules at the both pulmonary hilus and upper lobe of the right lung. Computed tomography (CT) angiography of the thorax confirmed arteriovenous malformation (AVM). However, effective treatment was impossible due to the poor physical condition; he died a few days later. Here we reported on the case of pulmonary arteriovenous malformations (PAVMs) being misdiagnosed as refractory heart failure.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1410
[Cu] Class update date: 141004
[Lr] Last revision date:141004
[Da] Date of entry for processing:141003
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.3978/j.issn.2072-1439.2014.07.39

  5 / 737307 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
PubMed Central Full text
Full text

[PMID]: 25276388
[Au] Autor:Tamburini N; Quarantotto F; Maniscalco P; Garelli E; Grossi W; Anania G; Cavallesco GN
[Ad] Address:Department of Morfology, Experimental Medicine and Surgery, Section of General and Thoracic Surgery, Sant'Anna Hospital, University of Ferrara, Ferrara, Italy....
[Ti] Title:Gastrointestinal bleeding in lung leiomyosarcoma history: report of a case.
[So] Source:J Thorac Dis;6(9):E163-5, 2014 Sep.
[Is] ISSN:2072-1439
[Cp] Country of publication:China
[La] Language:eng
[Ab] Abstract:The paper presents an unusual case of single small bowel metastasis from primary lung leiomyosarcoma (PLL) presenting with abdominal pain and gastrointestinal (GI) bleeding successfully treated by surgery with radical aim.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1410
[Cu] Class update date: 141004
[Lr] Last revision date:141004
[Da] Date of entry for processing:141003
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.3978/j.issn.2072-1439.2014.07.21

  6 / 737307 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
PubMed Central Full text
Full text

[PMID]: 25276380
[Au] Autor:Wang YX; Lo GG; Yuan J; Larson PE; Zhang X
[Ad] Address:1 Department of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China ; 2 Department of Diagnostic Radiology, Hong Kong Sanatorium & Hospital, Happy Valley, Hong Kong, China ; 3 Medical Physics and Resea...
[Ti] Title:Magnetic resonance imaging for lung cancer screen.
[So] Source:J Thorac Dis;6(9):1340-8, 2014 Sep.
[Is] ISSN:2072-1439
[Cp] Country of publication:China
[La] Language:eng
[Ab] Abstract:Lung cancer is the leading cause of cancer related death throughout the world. Lung cancer is an example of a disease for which a large percentage of the high-risk population can be easily identified via a smoking history. This has led to the investigation of lung cancer screening with low-dose helical/multi-detector CT. Evidences suggest that early detection of lung cancer allow more timely therapeutic intervention and thus a more favorable prognosis for the patient. The positive relationship of lesion size to likelihood of malignancy has been demonstrated previously, at least 99% of all nodules 4 mm or smaller are benign, while noncalcified nodules larger than 8 mm diameter bear a substantial risk of malignancy. In the recent years, the availability of high-performance gradient systems, in conjunction with phased-array receiver coils and optimized imaging sequences, has made MR imaging of the lung feasible. It can now be assumed a threshold size of 3-4 mm for detection of lung nodules with MRI under the optimal conditions of successful breath-holds with reliable gating or triggering. In these conditions, 90% of all 3-mm nodules can be correctly diagnosed and that nodules 5 mm and larger are detected with 100% sensitivity. Parallel imaging can significantly shorten the imaging acquisition time by utilizing the diversity of sensitivity profile of individual coil elements in multi-channel radiofrequency receive coil arrays or transmit/receive coil arrays to reduce the number of phase encoding steps required in imaging procedure. Compressed sensing technique accelerates imaging acquisition from dramatically undersampled data set by exploiting the sparsity of the images in an appropriate transform domain. With the combined imaging algorithm of parallel imaging and compressed sensing and advanced 32-channel or 64-channel RF hardware, overall imaging acceleration of 20 folds or higher can then be expected, ultimately achieve free-breathing and no ECG gating acquisitions in lung cancer MRI screening. Further development of protocols, more clinical trials and the use of advanced analysis tools will further evaluate the real significance of lung MRI.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1410
[Cu] Class update date: 141004
[Lr] Last revision date:141004
[Da] Date of entry for processing:141003
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.3978/j.issn.2072-1439.2014.08.43

  7 / 737307 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
PubMed Central Full text
Full text

[PMID]: 25276372
[Au] Autor:Pang X; Kozlowski N; Wu S; Jiang M; Huang Y; Mao P; Liu X; He W; Huang C; Li Y; Zhang H
[Ad] Address:1 State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China ; 2 The Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael's Hospital, University of Toronto, Toronto, O...
[Ti] Title:Construction and management of ARDS/sepsis registry with REDCap.
[So] Source:J Thorac Dis;6(9):1293-9, 2014 Sep.
[Is] ISSN:2072-1439
[Cp] Country of publication:China
[La] Language:eng
[Ab] Abstract:OBJECTIVE: The study aimed to construct and manage an acute respiratory distress syndrome (ARDS)/sepsis registry that can be used for data warehousing and clinical research. METHODS: The workflow methodology and software solution of research electronic data capture (REDCap) was used to construct the ARDS/sepsis registry. Clinical data from ARDS and sepsis patients registered to the intensive care unit (ICU) of our hospital formed the registry. These data were converted to the electronic case report form (eCRF) format used in REDCap by trained medical staff. Data validation, quality control, and database management were conducted to ensure data integrity. RESULTS: The clinical data of 67 patients registered to the ICU between June 2013 and December 2013 were analyzed. Of the 67 patients, 45 (67.2%) were classified as sepsis, 14 (20.9%) as ARDS, and eight (11.9%) as sepsis-associated ARDS. The patients' information, comprising demographic characteristics, medical history, clinical interventions, daily assessment, clinical outcome, and follow-up data, was properly managed and safely stored in the ARDS/sepsis registry. Data efficiency was guaranteed by performing data collection and data entry twice weekly and every two weeks, respectively. CONCLUSIONS: The ARDS/sepsis database that we constructed and manage with REDCap in the ICU can provide a solid foundation for translational research on the clinical data of interest, and a model for development of other medical registries in the future.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1410
[Cu] Class update date: 141004
[Lr] Last revision date:141004
[Da] Date of entry for processing:141003
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.3978/j.issn.2072-1439.2014.09.07

  8 / 737307 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
PubMed Central Full text
Full text

[PMID]: 25276365
[Au] Autor:Pei G; Zhou S; Han Y; Liu Z; Xu S
[Ad] Address:Department of Thoracic Surgery, Beijing Chest Hospital, Capital Medical University, Beijing 101149, China....
[Ti] Title:Risk factors for postoperative complications after lung resection for non-small cell lung cancer in elderly patients at a single institution in China.
[So] Source:J Thorac Dis;6(9):1230-8, 2014 Sep.
[Is] ISSN:2072-1439
[Cp] Country of publication:China
[La] Language:eng
[Ab] Abstract:OBJECTIVE: The purpose of this study was to assess the postoperative complications after lung resection for non-small cell lung cancer (NSCLC) in elderly patients and to identify possible associated risk factors. METHODS: All patients aged 70 years or older who underwent pulmonary resection for NSCLC by either an open approach or by a thoracoscopic approach between January 2003 and December 2013 at our institution were reviewed. Postoperative events were divided into minor and major complications. Risk factors for complications were assessed by univariate and multivariate logistic regression analysis. A matched case-control study was performed to determine if the utilization of video-assisted thoracic surgery (VATS) for lung resection for NSCLC in elderly patients' results in decreased complications compared with thoracotomy. RESULTS: During the study period, 476 consecutive patients (410 thoracotomy, 66 thoracoscopy) older than 70 years underwent resection for NSCLC. Postoperative complications occurred in 169 patients (35.5%) and the overall operative mortality was 2.3% (11 patients). Univariate predictors of complications included history of smoking (P=0.032), CCI scores ≥3 (P<0.001), pneumonectomy (P=0.016), as well as the duration of surgery (P=0.003). After multiple logistic regression analysis, CCI scores ≥3 [odds ratio (OR) =29.95, P<0.001], pneumonectomy (OR =2.26, P=0.029) and prolonged surgery (≥180 min) (OR =1.93, P=0.003) remained the only independent risk factors. After matching based on age, gender, the Charlson Comorbidity Index (CCI), pathologic stage, and the type of resection, there were 60 patients in each group. Patients had similar preoperative characteristics. A VATS approach resulted in a significantly lower rate of complications (25.0% vs. 43.3%, P=0.034) and a shorter median length of stay (19 days, range, 12 to 35 vs. 21 days, range, 13 to 38, P=0.013) compared with thoracotomy. CONCLUSIONS: Pulmonary resection for NSCLC in patients older than 70 years shows acceptable morbidity and mortality. Postoperative complications are more likely to develop in patients with CCI scores ≥3, those who undergo pneumonectomy, and those with a prolonged surgery. Thoracoscopic minimally invasive surgery for NSCLC in elderly patients is associated with fewer complications as well as a shorter hospital stay compared with thoracotomy.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1410
[Cu] Class update date: 141004
[Lr] Last revision date:141004
[Da] Date of entry for processing:141003
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.3978/j.issn.2072-1439.2014.07.23

  9 / 737307 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 25276601
[Au] Autor:Alves MV; Roberts D; Levine NB; DeMonte F; Hanna EY; Kupferman ME
[Ad] Address:Department of Medicine, Tufts University, Somerville, Massachusetts, United States....
[Ti] Title:Impact of Chemoradiotherapy on CSF Leak Repair after Skull Base Surgery.
[So] Source:J Neurol Surg B Skull Base;75(5):354-7, 2014 Oct.
[Is] ISSN:2193-6331
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:Background Transnasal endoscopic resection (TER) has become the treatment of choice for many skull base tumors. A major limitation of TER is the management of large dural defects and the need for repair of cerebrospinal fluid (CSF) leaks, particularly among patients who are treated with chemotherapy (CTX) or radiotherapy (RT). The objective of this study is to determine the impact of CTX and RT on the success of CSF leak repair after TER. Methods We performed a retrospective chart review of a single-institution experience of TER from 1992 to 2011. Results We identified 28 patients who had endoscopic CSF leak repair after resection of malignant skull base tumors. Preoperative RT was utilized in 18 patients, and 9 had undergone CTX. All patients required CSF leak repair with rotational flaps after cribriform and/or dural resection. CSF leak repair failed in three patients (11%). A history of RT or CTX was not associated with failed CSF leak repair. Conclusion Adjuvant or neoadjuvant CTX or RT is not associated with failed CSF leak repair. Successful CSF leak repair can be performed in patients with malignant skull base tumors with an acceptable risk profile.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1410
[Cu] Class update date: 141004
[Lr] Last revision date:141004
[Da] Date of entry for processing:141003
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1055/s-0034-1373659

  10 / 737307 MEDLINE  
              first record previous record
select
to print
Photocopy
PubMed Central Full text
Full text

[PMID]: 25276406
[Au] Autor:Schlussel AT; Gagliano RA; Seto-Donlon S; Eggerding F; Donlon T; Berenberg J; Lynch HT
[Ad] Address:1 Department of Surgery, Tripler Army Medical Center, Honolulu, HI, USA ; 2 University of Arizona Cancer Center at Dignity Health-St. Joseph's Hospital and Medical Center, Phoenix, AZ, USA ; 3 Genetics Laboratory, Huntington Medical Research Institutes, Pasadena, CA, USA ; 4 Ohana Genetics, Inc., Ho...
[Ti] Title:The evolution of colorectal cancer genetics-Part 2: clinical implications and applications.
[So] Source:J Gastrointest Oncol;5(5):336-44, 2014 Oct.
[Is] ISSN:2078-6891
[Cp] Country of publication:China
[La] Language:eng
[Ab] Abstract:The genetic understanding of colorectal cancer (CRC) continues to grow, and it is now estimated that 10% of the population has a known hereditary CRC syndrome. This article will examine the evolving surgical and medical management of hereditary CRC syndromes, and the impact of tumor genetics on therapy. This review will focus on the most common hereditary CRC-prone diseases seen in clinical practice, which include Lynch syndrome (LS), familial adenomatous polyposis (FAP) & attenuated FAP (AFAP), MutYH-associated polyposis (MAP), and serrated polyposis syndrome (SPS). Each section will review the current recommendations in the evaluation and treatment of these syndromes, as well as review surgical management and operative planning. A highly detailed multigeneration cancer family history with verified genealogy and pathology documentation whenever possible, coupled with germline mutation testing when indicated, is critically important to management decisions. Although caring for patients with these syndromes remains complex, the application of this knowledge facilitates better treatment of both individuals and their affected family members for generations to come.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1410
[Cu] Class update date: 141004
[Lr] Last revision date:141004
[Da] Date of entry for processing:141003
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.3978/j.issn.2078-6891.2014.068


page 1 of 73731 go to page                         
   


Refine the search
  Database : MEDLINE Advanced form   

    Search in field  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/PAHO/WHO - Latin American and Caribbean Center on Health Sciences Information