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[PMID]: 25876624
[Au] Autor:Zhou B; Ren J; Li J; Guo A; Cao X; Chang J
[Ad] Address:Department of General Surgery, First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.
[Ti] Title:[Regenerative surgery: promises, strategies, and translational perspectives].
[So] Source:Zhonghua Wai Ke Za Zhi;53(1):72-6, 2015 Jan 1.
[Is] ISSN:0529-5815
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:Regenerative surgery is an emerging multidisciplinary field that has the potential to transform the surgical treatment for diseases and injuries. This article provides a brief overview of the history of surgery and regenerative medicine, introduces the new concept of regenerative surgery, describes the surgical procedures, and discusses the role of surgeons in developing and implementing these technologies. Insights gained from recent clinical research of regenerative medicine are beginning to yield three strategies for regenerative therapies for surgical diseases, and this review also provides the challenges and translational perspectives of these different strategies.
[Mh] MeSH terms primary: General Surgery/trends
Regenerative Medicine
[Mh] MeSH terms secundary: Biomedical Research
Humans
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE; REVIEW
[Em] Entry month:1505
[Js] Journal subset:IM
[Da] Date of entry for processing:150416
[St] Status:MEDLINE

  2 / 760383 MEDLINE  
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[PMID]: 25876622
[Au] Autor:Jiang Z
[Ad] Address:Email: jiangzm@imicams.ac.cn.
[Ti] Title:[A brief history of surgical nutrition in China].
[So] Source:Zhonghua Wai Ke Za Zhi;53(1):47-9, 2015 Jan 1.
[Is] ISSN:0529-5815
[Cp] Country of publication:China
[La] Language:chi
[Mh] MeSH terms primary: General Surgery/trends
Nutritional Status
[Mh] MeSH terms secundary: China
Humans
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1505
[Js] Journal subset:IM
[Da] Date of entry for processing:150416
[St] Status:MEDLINE

  3 / 760383 MEDLINE  
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[PMID]: 25876621
[Au] Autor:Li H; Sun Z; Zhang Y
[Ti] Title:[A brief history of the development of Chinese Urology].
[So] Source:Zhonghua Wai Ke Za Zhi;53(1):42-6, 2015 Jan 1.
[Is] ISSN:0529-5815
[Cp] Country of publication:China
[La] Language:chi
[Mh] MeSH terms primary: Urology/trends
[Mh] MeSH terms secundary: China
Humans
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1505
[Js] Journal subset:IM
[Da] Date of entry for processing:150416
[St] Status:MEDLINE

  4 / 760383 MEDLINE  
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[PMID]: 25876620
[Au] Autor:Zhao Y
[Ad] Address:Email: shenwaisuo@126.com.
[Ti] Title:[A brief history of neurosurgery in the mainland of China].
[So] Source:Zhonghua Wai Ke Za Zhi;53(1):33-41, 2015 Jan 1.
[Is] ISSN:0529-5815
[Cp] Country of publication:China
[La] Language:chi
[Mh] MeSH terms primary: Neurosurgery/trends
Neurosurgical Procedures/trends
[Mh] MeSH terms secundary: China
Humans
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1505
[Js] Journal subset:IM
[Da] Date of entry for processing:150416
[St] Status:MEDLINE

  5 / 760383 MEDLINE  
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[PMID]: 25876619
[Au] Autor:Gao S; Liu Y; Geng Q; Zhao H; Wang J
[Ti] Title:[Development brief history of thoracic surgery in China].
[So] Source:Zhonghua Wai Ke Za Zhi;53(1):27-32, 2015 Jan 1.
[Is] ISSN:0529-5815
[Cp] Country of publication:China
[La] Language:chi
[Mh] MeSH terms primary: Thoracic Surgical Procedures/trends
[Mh] MeSH terms secundary: China
Humans
Thoracic Surgery/trends
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1505
[Js] Journal subset:IM
[Da] Date of entry for processing:150416
[St] Status:MEDLINE

  6 / 760383 MEDLINE  
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[PMID]: 25876682
[Au] Autor:Jin X
[Ad] Address:Email: zhujing7@msn.cn.
[Ti] Title:[Development history of Chinese behavioral pediatrics].
[So] Source:Zhonghua Er Ke Za Zhi;53(2):95-6, 2015 Feb.
[Is] ISSN:0578-1310
[Cp] Country of publication:China
[La] Language:chi
[Mh] MeSH terms primary: Pediatrics/trends
[Mh] MeSH terms secundary: Child
Child Development
China
Humans
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1505
[Js] Journal subset:IM
[Da] Date of entry for processing:150416
[St] Status:MEDLINE

  7 / 760383 MEDLINE  
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[PMID]: 25876681
[Au] Autor:Qian S; Xu F; Lu Z; Zhao X; Zhu Y
[Ad] Address:Email: syqian1211@163.com.
[Ti] Title:[Development history of Chinese pediatric critical care medicine].
[So] Source:Zhonghua Er Ke Za Zhi;53(2):93-4, 2015 Feb.
[Is] ISSN:0578-1310
[Cp] Country of publication:China
[La] Language:chi
[Mh] MeSH terms primary: Critical Care/trends
Pediatrics/trends
[Mh] MeSH terms secundary: China
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1505
[Js] Journal subset:IM
[Da] Date of entry for processing:150416
[St] Status:MEDLINE

  8 / 760383 MEDLINE  
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PubMed Central Full text
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[PMID]: 25866636
[Au] Autor:Stevens WW; Peters AT; Suh L; Norton JE; Kern RC; Conley DB; Chandra RK; Tan BK; Grammer LC; Harris KE; Carter RG; Kato A; Urbanek M; Schleimer RP; Hulse KE
[Ad] Address:Division of Allergy-Immunology Department of Medicine, Northwestern University Feinberg School of Medicine Chicago, Illinois, USA....
[Ti] Title:A retrospective, cross-sectional study reveals that women with CRSwNP have more severe disease than men.
[So] Source:Immun Inflamm Dis;3(1):14-22, 2015 Mar.
[Is] ISSN:2050-4527
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Up to 50% of patients with chronic rhinosinusitis (CRS) have comorbid asthma, and we have reported that a subset of CRS patients who have nasal polyps (CRSwNP) have elevated autoantigen-specific antibodies within their nasal polyps (NP). While increases in the prevalence and/or severity of both asthma and autoimmunity in women are well characterized, it is not known whether CRSwNP is more severe or frequent in women than men. We sought to determine whether CRSwNP demonstrated sex-specific differences in frequency and/or severity. Using a retrospectively collected database of tertiary care patients (n = 1393), we evaluated the distribution of sex in patients with CRSwNP with or without comorbid asthma or aspirin hypersensitivity. We further compared the severity of sinus disease between men and women with CRSwNP. Although women comprised 55% of CRS patients without NP (CRSsNP), a significantly smaller proportion of CRSwNP patients were female (38%, P < 0.001). Interestingly, women with CRSwNP were significantly more likely than men to have comorbid asthma (P < 0.001), and 61% of patients with the most severe form of disease (aspirin-exacerbated respiratory disease (CRSwNP plus asthma plus aspirin sensitivity)) were women (P < 0.05). Women with CRSwNP were significantly more likely to have taken oral steroids, and were more likely to have a history of revision surgeries (P < 0.05) compared to men. These data suggest that women with CRSwNP have more severe disease than men in a tertiary care setting. Future studies are needed to elucidate the mechanisms that drive disease severity in men and women, paving the way for the development of personalized treatment strategies for CRSwNP based on sex.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1504
[Cu] Class update date: 150516
[Lr] Last revision date:150516
[Da] Date of entry for processing:150413
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1002/iid3.46

  9 / 760383 MEDLINE  
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[PMID]: 25088233
[Au] Autor:Lu Y; Yeung C; Radmanesh A; Wiemann R; Black PM; Golby AJ
[Ad] Address:Department of Neurosurgery, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. Electronic address: ylu4@partners.org....
[Ti] Title:Comparative effectiveness of frame-based, frameless, and intraoperative magnetic resonance imaging-guided brain biopsy techniques.
[So] Source:World Neurosurg;83(3):261-8, 2015 Mar.
[Is] ISSN:1878-8750
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVE: To compare the diagnostic yield and safety profiles of intraoperative magnetic resonance imaging (MRI)-guided needle brain biopsy with 2 traditional brain biopsy methods: frame-based and frameless stereotactic brain biopsy. METHODS: A retrospective analysis was performed of 288 consecutive needle brain biopsies in 277 patients undergoing stereotactic brain biopsy with any of the 3 biopsy methods at Brigham and Women's Hospital from 2000-2008. Variables including age, sex, history of radiation and previous surgery, pathology results, complications, and postoperative length of hospital stay were analyzed. RESULTS: Over the course of 8 years, 288 brain biopsies were performed. Of these, 253 (87.8%) biopsies yielded positive diagnostic tissue. Young age (<40 years old) and history of brain radiation or surgery were significant negative predictors for a positive biopsy diagnostic yield. Excluding patients with prior radiation or surgeries, no significant difference in diagnostic yield was detected among the 3 groups, with frame-based biopsies yielding 96.9%, frameless biopsies yielding 91.8%, and intraoperative MRI-guided needle biopsies yielding 89.9% positive diagnostic yield. Serious adverse events occurred 19 biopsies (6.6%). Intraoperative MRI-guided brain biopsies were associated with less serious adverse events and the shortest postoperative hospital stay. CONCLUSIONS: Frame-based, frameless stereotactic, and intraoperative MRI-guided brain needle biopsy techniques have comparable diagnostic yield for patients with no prior treatments (either radiation or surgery). Intraoperative MRI-guided brain biopsy is associated with fewer serious adverse events and shorter hospital stay.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1504
[Cu] Class update date: 150516
[Lr] Last revision date:150516
[Js] Journal subset:IM
[St] Status:In-Data-Review

  10 / 760383 MEDLINE  
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[PMID]: 25733855
[Au] Autor:Harris K
[Ad] Address:Department of Mathematics, University of California, Berkeley, CA 94703 harris.kelley@gmail.com.
[Ti] Title:Evidence for recent, population-specific evolution of the human mutation rate.
[So] Source:Proc Natl Acad Sci U S A;112(11):3439-44, 2015 Mar 17.
[Is] ISSN:1091-6490
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:As humans dispersed out of Africa they adapted to new environmental challenges, including changes in exposure to mutagenic solar radiation. Humans in temperate latitudes have acquired light skin that is relatively transparent to UV light, and some evidence suggests that their DNA damage response pathways have also experienced local adaptation. This raises the possibility that different populations have experienced different selective pressures affecting genome integrity. Here, I present evidence that the rate of a particular mutation type has recently increased in the European population, rising in frequency by 50% during the 40,000-80,000 y since Europeans began diverging from Asians. A comparison of SNPs private to Africa, Asia, and Europe in the 1000 Genomes data reveals that private European variation is enriched for the transition 5'-TCC-3' → 5'-TTC-3'. Although it is not clear whether UV played a causal role in changing the European mutational spectrum, 5'-TCC-3' → 5'-TTC-3' is known to be the most common somatic mutation present in melanoma skin cancers, as well as the mutation most frequently induced in vitro by UV. Regardless of its causality, this change indicates that DNA replication fidelity has not remained stable even since the origin of modern humans and might have changed numerous times during our recent evolutionary history.
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Em] Entry month:1503
[Cu] Class update date: 150516
[Lr] Last revision date:150516
[Js] Journal subset:IM
[St] Status:In-Process
[do] DOI:10.1073/pnas.1418652112


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