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[PMID]: 26483070
[Au] Autor:Severino A; Castagneto-Gissey L; Raffaelli M; Gastaldelli A; Capristo E; Iaconelli A; Guidone C; Callari C; Bellantone R; Mingrone G
[Ad] Address:Department of Internal Medicine, Catholic University, Rome, Italy....
[Ti] Title:Early effect of Roux-en-Y gastric bypass on insulin sensitivity and signaling.
[So] Source:Surg Obes Relat Dis;12(1):42-7, 2016 Jan.
[Is] ISSN:1878-7533
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: A large body of literature indicates the rapidity with which Roux-en-Y gastric bypass (RYGB) improves glycemic control. However, the underlying physiologic mechanisms are still a matter of debate. SETTING: Catholic University, School of Medicine, Rome, Italy. METHODS: Ten morbidly obese patients, before and 4 weeks after RYGB, and 10 healthy controls were studied. We measured insulin sensitivity as the homeostasis model assessment-estimated insulin resistance (HOMA-IR) and by the euglycemic hyperinsulinemic clamp, and phosphorylation of protein kinase B (Akt) on Ser473 and Thr308 and of GSK3 α-ß on Ser 9 and Ser21 in skeletal muscle biopsy specimens by Western blot analysis. RESULTS: Obese patients before RYGB displayed reduced insulin sensitivity (M value) and clearance and increased fasting Akt phosphorylation on Ser473 compared with controls. M significantly increased after surgery (from 2.6±0.6 to 2.8±0.7 mg/kg fat free mass/min, P = .026) but remained far below the values in controls (10.0±3.8 mg/kg fat free mass/min, P<.001). Insulin clearance increased from 453.5±117.5 to 555.2±61.6 (P = .00076), becoming similar to that of controls 582.2±59.0 mU/m(2)/min. HOMA-IR decreased from 4.1±0.07 to 2.3±0.5 (P = .004), becoming comparable with controls (2.2±0.9). The hyperphosphorylation of Akt on Ser473 observed at fasting before RYGB was significantly reduced thereafter, becoming similar to that of healthy controls; the other phosphorylation states remained unchanged. CONCLUSIONS: Following RYGB, we found a prompt improvement of hepatic insulin resistance with normalization of hepatic insulin clearance and a small amelioration of whole-body insulin sensitivity. The supranormal levels of Akt Ser473 observed at fast in the skeletal muscle tissue at baseline were normalized after RYGB, and their changes correlated with those of both hepatic and peripheral insulin resistance. Although other mechanisms of action, such as the effect of weight loss and reduced food intake, cannot be excluded, the reduction of muscle Akt hyperphosphorylation on the serine residue can play a role in the early improvement of insulin sensitivity.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1601
[Js] Journal subset:IM
[St] Status:In-Data-Review

  2 / 1957510 MEDLINE  
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[PMID]: 25510589
[Au] Autor:Sánchez-Holgado J; Gonzalez-Gonzalez J; Torijano-Casalengua ML
[Ad] Address:Centro de Salud Santa Olalla, Área de Gestión Integrada Talavera de la Reina, Talavera de la Reina, Toledo, España. Electronic address: sanchezholgado@hotmail.com.
[Ti] Title:Percepción sobre conocimientos en cuidados paliativos de los trabajadores de los centros sociosanitarios de personas mayores de una zona básica de salud. [Perception of knowledge in palliative care housing for the elderly workers in a basic health zone].
[So] Source:Semergen;42(1):19-24, 2016 Jan-Feb.
[Is] ISSN:1578-8865
[Cp] Country of publication:Spain
[La] Language:spa
[Ab] Abstract:OBJECTIVE: To analyze the level of knowledge in palliative care that health and non health housing for the elderly workers refer, to study the differences between professional categories and to detect their interest in receiving palliative care training. PATIENTS AND METHODS: Cross-sectional study conducted among physicians, nurses, physiotherapists, nursing assistant and occupational therapists applying a questionary assisting terminal patients with 22 items grouped into four sections: generalities palliative care, physical care, psycho-emotional and spiritual. Each question is answered using a four point scale in much-regulate-little-nothing. RESULTS: 86.8% of respondents know quite what they mean or regular palliative care. 3.8% consider themselves sufficiently trained in palliative care. We found significant differences in non-pharmacological management of dyspnea and insomnia where concerns have less knowledge worker. Medicine and nursing reported having more knowledge in the recognition of a tumor ulcer. CONCLUSIONS: There is a very high interest in receiving palliative care training and these are considered very useful. Required impact on the acquisition of knowledge in the medical staff not optional as to non-pharmacological management of major symptoms It also emphasizes the need to approach not to question the patient's pain by physicians. The test to detect cognitive impairment are not well known for nursing assistants. The spiritual realm is the acceptable level of knowledge on the part of all professional categories surveyed.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1601
[Js] Journal subset:IM
[St] Status:In-Data-Review

  3 / 1957510 MEDLINE  
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[PMID]: 26802593
[Au] Autor:Hermann CP; Head BA; Black K; Singleton K
[Ad] Address:Professor and PhD Program Director (Hermann), Assistant Professor (Black), Assistant Professor (Singleton), University of Louisville School of Nursing, Louisville, KY 40292.. Electronic address: carla.hermann@louisville.edu....
[Ti] Title:Preparing Nursing Students for Interprofessional Practice: The Interdisciplinary Curriculum for Oncology Palliative Care Education.
[So] Source:J Prof Nurs;32(1):62-71, 2016 Jan-Feb.
[Is] ISSN:1532-8481
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Interprofessional educational experiences for baccalaureate nursing students are essential to prepare them for interprofessional communication, collaboration, and team work. Nurse educators are ideally positioned to develop and lead such initiatives. The purpose of this article is to describe the development and implementation of an interprofessional education (IPE) project involving students in nursing, medicine, social work, and chaplaincy. The Interdisciplinary Curriculum for Oncology Palliative Care Education project uses team-based palliative oncology education as the framework for teaching students interprofessional practice skills. The need for IPE is apparent, but there are very few comprehensive, successful projects for nurse educators to use as models. This article describes the development of the curriculum by the interprofessional faculty team. Issues encountered by nursing faculty members as they implemented the IPE experience are discussed. Solutions developed to address the issues and ongoing challenges are presented. This project can serve as a model of a successful IPE initiative involving nursing students.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1601
[Js] Journal subset:IM; N
[St] Status:In-Data-Review

  4 / 1957510 MEDLINE  
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[PMID]: 26802918
[Au] Autor:Hoover R; Sheth P; Burde A
[Ti] Title:Determining the accuracy of open-access databases for identifying commonly prescribed oral medications.
[So] Source:J Am Pharm Assoc (2003);56(1):37-40, 2016 Jan.
[Is] ISSN:1544-3450
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVES: To compare the accuracy of open-access medication identification databases in identifying commonly prescribed oral tablets and capsules. METHODS: We compiled a dataset from the most frequently prescribed medications in 2012 and 2013 by total prescription volume. Imprints for the medications were obtained from the Food and Drug Administration label information accessed via the National Library of Medicine's (NLM) DailyMed. The imprints were used to determine if the correct medication could be identified in the open-access medication identification databases Drugs.com, Healthline, NLM's Pillbox, RxList, and WebMD by means of the imprints alone. A general web search using the imprints as key words via Google search engine was also conducted to mimic the lay public's approach to identifying an unknown medication. RESULTS: Database accuracy of search results ranged from 26.5% to 89.27% with the NLM Pillbox having the highest accuracy when using tablet/capsule imprint information alone. The secondary web search with the use of the Google search engine yielded 75.7% accuracy in using imprints as search terms to identify websites leading to the appropriate drugs. Drugs.com was listed as the first site for the majority of Google searches and was 86.44% accurate. CONCLUSION: Open-access databases are available to help identify oral tablets and capsules and they have a relatively high success rate of identifying commonly prescribed medications. However no database is 100% accurate, which means that the risk involved with patients identifying their own medications is substantial. Patients should be highly encouraged by all health care practitioners to consult their pharmacist or primary health care provider to prevent misidentification and subsequent misadministration.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1601
[Js] Journal subset:IM
[St] Status:In-Data-Review

  5 / 1957510 MEDLINE  
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[PMID]: 26802996
[Au] Autor:Society for Adolescent Health and Medicine
[Ti] Title:Emergency Contraception for Adolescents and Young Adults: Guidance for Health Care Professionals.
[So] Source:J Adolesc Health;58(2):245-8, 2016 Feb.
[Is] ISSN:1879-1972
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1601
[Js] Journal subset:IM
[St] Status:In-Data-Review

  6 / 1957510 MEDLINE  
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[PMID]: 26802995
[Au] Autor:Varan AK; Harriman KH; Winter K; Thun MD; McDonald EC
[Ad] Address:CDC/CSTE Applied Epidemiology Fellowship, Atlanta, Georgia; County of San Diego Health and Human Services Agency, San Diego, California; Division of Global Migration and Quarantine, Centers for Disease Control and Prevention, San Diego, California. Electronic address: vvl5@cdc.gov....
[Ti] Title:Economic and Social Impact of Pertussis Among Adolescents in San Diego County.
[So] Source:J Adolesc Health;58(2):241-4, 2016 Feb.
[Is] ISSN:1879-1972
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:PURPOSE: During recent pertussis epidemics, adolescents have experienced a large burden of disease. We assessed the impact of pertussis among San Diego adolescents and their households. METHODS: Parents of pertussis patients aged 13-17 years were surveyed about health care utilization, missed work and school, and other factors. Costs of medical visits, medication use, and lost wages were estimated. RESULTS: The parents of 53 (of 108 [49%]) eligible 2013 pertussis patients were interviewed; 51 (96%) of these patients previously received tetanus, diphtheria, and acellular pertussis vaccine. Medical visits included primary care (81%), urgent care (11%), and emergency department (9%); all patients received antibiotics. Forty-seven households (89%) received a post-exposure prophylaxis recommendation, and five (9%) reported ≥1 unpaid parental leave day. Thirty-eight patients (72%) missed ≥1 school day (mean = 5.4 days). Societal costs were estimated at $315.15 per household and $236,047.35 in San Diego during 2013-2014. CONCLUSIONS: Even among vaccinated adolescents, pertussis can result in considerable societal costs.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1601
[Js] Journal subset:IM
[St] Status:In-Data-Review

  7 / 1957510 MEDLINE  
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[PMID]: 26802994
[Au] Autor:Culyba AJ; Ginsburg KR; Fein JA; Branas CC; Richmond TS; Wiebe DJ
[Ad] Address:Craig-Dalsimer Division of Adolescent Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: culyba@email.chop.edu....
[Ti] Title:Protective Effects of Adolescent-Adult Connection on Male Youth in Urban Environments.
[So] Source:J Adolesc Health;58(2):237-40, 2016 Feb.
[Is] ISSN:1879-1972
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:PURPOSE: Positive adult connection has been linked with protective effects among U.S. adolescents. Less is known about the impact of adult connection across multiple health domains for youth in low-resource urban environments. We examined the associations between adult connection and school performance, substance use, and violence exposure among youth in low-resource neighborhoods. METHODS: We recruited a population-based random sample of 283 male adolescents in Philadelphia. Age-adjusted logistic regression tested whether positive adult connection promoted school performance and protected against substance use and violence exposure. RESULTS: Youth with a positive adult connection had significantly higher odds of good school performance (odds ratio [OR], 2.8; p < .05), and lower odds of alcohol use (OR, .4; p < .05), violence involvement (OR, .3-.4; p < .05), and violence witnessing (OR, .3; p < .05). CONCLUSIONS: Promoting adult connection may help safeguard youth in urban contexts. Youth-serving professionals should consider assessing adult connection as part of a strengths-based approach to health promotion for youth in low-resource neighborhoods.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1601
[Js] Journal subset:IM
[St] Status:In-Data-Review

  8 / 1957510 MEDLINE  
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[PMID]: 26802993
[Au] Autor:Stults CB; Javdani S; Greenbaum CA; Kapadia F; Halkitis PN
[Ad] Address:Center for Health, Identity, Behavior and Prevention Studies, The Steinhardt School of Culture, Education, and Human Development, New York University, New York, New York; Department of Applied Psychology, The Steinhardt School of Culture, Education, and Human Development, New York University, New Yo...
[Ti] Title:Intimate Partner Violence and Sex Among Young Men Who Have Sex With Men.
[So] Source:J Adolesc Health;58(2):215-22, 2016 Feb.
[Is] ISSN:1879-1972
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:PURPOSE: Among young men who have sex with men (YMSM) few studies have examined the relationship between intimate partner violence (IPV) perpetration versus victimization and sexual behaviors. METHODS: Using data from n = 528 urban YMSM, multinomial logistic regression models were built to examine the distinct relationships between any IPV, victimization, and perpetration with condomless sex in the previous 30 days, controlling for key sociodemographic characteristics. RESULTS: In this sample of YMSM, lifetime experience of any IPV was associated with increased odds of recent condomless oral (adjusted odds ratio [AOR] = 1.81, 95% confidence interval [CI] = 1.21-2.72) and anal receptive sex (AOR= 2.29, 95% CI = 1.22-4.31). IPV victimization was associated with a greater likelihood of condomless receptive anal sex (AOR= 2.12, 95% CI = 1.15-3.93) whereas IPV perpetration was associated with increased odds of condomless receptive (AOR= 2.11, 95% CI = 1.14-3.91) and insertive (AOR= 2.21, 95% CI = 1.06-4.59) anal sex. CONCLUSIONS: Among YMSM, reports of both IPV perpetration and victimization were associated with increased odds of recent condomless sex. These findings indicate that the need for IPV prevention and intervention programs for this new generation of YMSM is highly warranted.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1601
[Js] Journal subset:IM
[St] Status:In-Data-Review

  9 / 1957510 MEDLINE  
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[PMID]: 26802992
[Au] Autor:Clawson AH; Robinson LA; Ali JS
[Ad] Address:Department of Psychiatry, Centers for Behavioral and Preventive Medicine, Alpert Medical School of Brown University and The Miriam Hospital, Providence, Rhode Island. Electronic address: ashley_clawson@brown.edu.
[Ti] Title:Physician Advice to Adolescents About Smoking: Who Gets Advised and Who Benefits Most?
[So] Source:J Adolesc Health;58(2):195-201, 2016 Feb.
[Is] ISSN:1879-1972
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:PURPOSE: The Clinical Practice Guidelines instruct physicians to ask their patients about smoking and to advise against tobacco use. Physicians are urged especially to attend to racial minorities and teens because of these groups' increased susceptibility to smoking. Research on race and physician advice against smoking has produced contradictory findings. The purpose of this study is to clarify the relationships between physician communication about tobacco, race, and smoking among adolescents. METHODS: This cross-sectional retrospective study explored (1) racial differences in rates of receiving physician communication and (2) whether the relationship between physician communication and smoking among adolescents was moderated by race. Multiple measures of smoking status were used (e.g., intentions to quit, quit attempts, quits, relapse status). We used a large (N = 5,154), predominately African-American (82.9%) sample of 11th graders. RESULTS: Regular smokers were more likely to be screened about smoking. African Americans were more frequently advised against tobacco than Caucasians. Among African Americans, nonsmokers were most likely to be both screened and advised; among Caucasians, regular were most likely to be screened and advised. Overall, physician intervention was associated with greater benefits for young African Americans, including fewer intentions to smoke, greater likelihood of quitting, and less relapse. CONCLUSIONS: Physician communication about smoking may hold particular promise for African-American teens, reducing health disparities because of racial differences in smoking-related mortality and morbidity. Physicians should be encouraged to screen and advise all young people about tobacco, regardless of race or smoking status.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1601
[Js] Journal subset:IM
[St] Status:In-Data-Review

  10 / 1957510 MEDLINE  
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[PMID]: 26802991
[Au] Autor:Scurr J; Brown N; Smith J; Brasher A; Risius D; Marczyk A
[Ad] Address:Department of Sport and Exercise Science, University of Portsmouth, Portsmouth, United Kingdom. Electronic address: Joanna.scurr@port.ac.uk....
[Ti] Title:The Influence of the Breast on Sport and Exercise Participation in School Girls in the United Kingdom.
[So] Source:J Adolesc Health;58(2):167-73, 2016 Feb.
[Is] ISSN:1879-1972
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:PURPOSE: Emerging evidence suggests that breasts may be a barrier to physical activity for adult females. With only 12% of the UK 14-year-old girls achieving exercise guidelines, to understand deterrents to exercise in this population, we should consider whether breasts may also influence sport and exercise participation in school girls. This survey-based study investigated the influence of the breast on sport and exercise participation and breast-specific concerns in the UK school girls. METHODS: A survey was developed to assess demographics, breast characteristics, breast-specific concerns in sports, breast knowledge, views on breast education, and sport participation. Chi-squared tests assessed associations between participation and breast size, sports bra use, and breast concerns. RESULTS: Two thousand eighty-nine school girls aged 11-18 years completed the survey, for 97 their breasts had begun developing and 96% reported wearing breast support. Forty-six percent of girls reported that their breasts had some effect on their participation in compulsory sports and exercise, which was more prevalent in girls aged 13-14 years (51%) and in larger-breasted girls (63%). More than 50% reported never wearing a sports bra during sports. Breast concerns were high with 73% reporting ≥1 breast-specific concern in sports; with breast bounce being most prevalent (38%). CONCLUSIONS: As most of the breast concerns raised in this survey could be addressed via education and 87% of girls wanted to know more about breasts, this study demonstrates a need for breast education for school girls, which may reduce the influence of the breast on sport and exercise participation.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1601
[Js] Journal subset:IM
[St] Status:In-Data-Review


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