Database : MEDLINE Search on : medicine [Words] References found : 1730121 [refine] Displaying: 1 .. 10   in format [Detailed]

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[PMID]: 23462379 [Au] Autor: Stirpe F [Ad] Address: Alma Mater Studiorum Università di Bologna, Via S. Petronio Vecchio 19, I-40125 Bologna, Italy. Electronic address: fiorenzostirpe@libero.it. [Ti] Title: Ribosome-inactivating proteins: From toxins to useful proteins. [So] Source: Toxicon;67:12-6, 2013 Jun 1. [Is] ISSN: 1879-3150 [Cp] Country of publication: England [La] Language: eng [Ab] Abstract: Ribosome-inactivating proteins (RIPs) either single-chain (type 1) or two-chain (type 2) are frequent in plants, often in multiple forms. They are RNA N-glycosidases, have antiviral, antifungal and insecticidal activity. Their expression in plants is increased under stressful conditions. They are investigated for practical applications in medicine and in agriculture. In medicine, RIPs have been linked to, or fused with, appropriate antibodies or other carriers to form "immunotoxins" or other conjugates specifically toxic to the cells target of the carrier, with the aim of eliminating malignant or other undesired cells. In agriculture, it has been observed that an enhanced expression of RIPs confers to plants an increased resistance to viruses, fungi, insects, and also to drought and salinity. [Pt] Publication type: JOURNAL ARTICLE [Em] Entry month: 1305 [Js] Journal subset: IM [St] Status: In-Data-Review

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[PMID]: 23097520 [Au] Autor: Gualdrini G; Bordy JM; Daures J; Fantuzzi E; Ferrari P; Mariotti F; Vanhavere F [Ad] Address: ENEA, Agenzia Nazionale per le Nuove tecnologie, l'Energia e lo Sviluppo economico sostenibile, 16, via dei colli, 40136 Bologna, Italy. [Ti] Title: Air kerma to HP(3) conversion coefficients for photons from 10 keV to 10 MeV, calculated in a cylindrical phantom. [So] Source: Radiat Prot Dosimetry;154(4):517-21, 2013. [Is] ISSN: 1742-3406 [Cp] Country of publication: England [La] Language: eng [Ab] Abstract: In the framework of the ORAMED project (Optimization of RAdiation protection for MEDical staff), funded by the European Union Seventh Framework Programme, different studies were aimed at improving the quality of radiation protection in interventional radiology and nuclear medicine. The main results of the project were presented during a final workshop held in Barcelona in January 2011, the proceedings of which are available in the open literature. One of the ORAMED tasks was focused on the problem of eye-lens photon exposure of the medical staff, a topic that gained more importance especially after the ICRP decision to lower the limiting equivalent dose to 20 mSv per year. The present technical note has the scope, besides briefly summarising the physical reasons of the proposal and the practical implications, to provide, in tabular form, a set of air kerma to Hp(3) conversion coefficients based on the adoption of a theoretical cylindrical model that is well suited for reproduction of the mass and the shape of a human head. [Pt] Publication type: JOURNAL ARTICLE [Em] Entry month: 1305 [Js] Journal subset: IM [St] Status: In-Data-Review [do] DOI: 10.1093/rpd/ncs269

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[PMID]: 23045717 [Au] Autor: Teles P; Carmen de Sousa M; Paulo G; Santos J; Pascoal A; Cardoso G; Lança I; Matela N; Janeiro L; Sousa P; Carvoeiras P; Parafita R; Santos AI; Simãozinho P; Vaz P [Ad] Address: Instituto Superior Técnico/Instituto Tecnológico e Nuclear, Estrada Nacional 10, Sacavém 2686-953, Portugal. [Ti] Title: Estimation of the collective dose in the Portuguese population due to medical procedures in 2010. [So] Source: Radiat Prot Dosimetry;154(4):446-58, 2013. [Is] ISSN: 1742-3406 [Cp] Country of publication: England [La] Language: eng [Ab] Abstract: In a wide range of medical fields, technological advancements have led to an increase in the average collective dose in national populations worldwide. Periodic estimations of the average collective population dose due to medical exposure is, therefore of utmost importance, and is now mandatory in countries within the European Union (article 12 of EURATOM directive 97/43). Presented in this work is a report on the estimation of the collective dose in the Portuguese population due to nuclear medicine diagnostic procedures and the Top 20 diagnostic radiology examinations, which represent the 20 exams that contribute the most to the total collective dose in diagnostic radiology and interventional procedures in Europe. This work involved the collaboration of a multidisciplinary taskforce comprising representatives of all major Portuguese stakeholders (universities, research institutions, public and private healthcare providers, administrative services of the National Healthcare System, scientific and professional associations and private service providers). This allowed us to gather a comprehensive amount of data necessary for a robust estimation of the collective effective dose to the Portuguese population. The methodology used for data collection and dose estimation was based on European Commission recommendations, as this work was performed in the framework of the European wide Dose Datamed II project. This is the first study estimating the collective dose for the population in Portugal, considering such a wide national coverage and range of procedures and consisting of important baseline reference data. The taskforce intends to continue developing periodic collective dose estimations in the future. The estimated annual average effective dose for the Portuguese population was of 0.080±0.017 mSv caput(-1) for nuclear medicine exams and of 0.96±0.68 mSv caput(-1) for the Top 20 diagnostic radiology exams. [Pt] Publication type: JOURNAL ARTICLE [Em] Entry month: 1305 [Js] Journal subset: IM [St] Status: In-Data-Review [do] DOI: 10.1093/rpd/ncs258

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[PMID]: 23670669 [Au] Autor: Geyer M [Ad] Address: Wissenschaftlicher Leiter der Akademie für Psychotherapie Erfurt. [Ti] Title: Die Leipziger Universitätsklinik für Psychosomatik und Psychotherapie wird 60. [The university hospital for psychosomatic medicine and psychotherapy turns 60]. [So] Source: Psychother Psychosom Med Psychol;63(5):165-6, 2013 May. [Is] ISSN: 0937-2032 [Cp] Country of publication: Germany [La] Language: ger [Pt] Publication type: JOURNAL ARTICLE [Em] Entry month: 1305 [Js] Journal subset: IM [St] Status: In-Data-Review [do] DOI: 10.1055/s-0032-1333059

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[PMID]: 23668657 [Au] Autor: Boggess BR; Bytomski JR [Ad] Address: Department of Orthopedics, Duke University Medical Center, 103 Cypress Mill Road, Morrisville, NC 27560, USA. [Ti] Title: Medicolegal aspects of sports medicine. [So] Source: Prim Care;40(2):525-35, 2013 Jun. [Is] ISSN: 1558-299X [Cp] Country of publication: United States [La] Language: eng [Ab] Abstract: Legal issues in sports medicine are rapidly developing and establishing an important body of jurisprudence that defines the legal rights and duties of all those involved with protecting the health and safety of athletes. The law makes important distinctions between the relevant duty of care owed to high-school, college, and professional athletes because of the differing legal relationships that arise out of athletic participation at different levels of competition. [Pt] Publication type: JOURNAL ARTICLE [Em] Entry month: 1305 [Js] Journal subset: IM [St] Status: In-Data-Review

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[PMID]: 23668645 [Au] Autor: Becker JA; Stumbo JR [Ad] Address: Primary Care Sports Medicine Fellowship, Jewish Hospital and University of Louisville, Louisville, KY, USA; Department of Family and Geriatric Medicine, University of Louisville, Louisville, KY, USA. Electronic address: jon.becker@louisville.edu. [Ti] Title: Back pain in adults. [So] Source: Prim Care;40(2):271-88, 2013 Jun. [Is] ISSN: 1558-299X [Cp] Country of publication: United States [La] Language: eng [Ab] Abstract: This article provides a summary of the many causes of back pain in adults. There is an overview of the history and physical examination with attention paid to red flags that alert the clinician to more worrisome causes of low back pain. An extensive differential diagnosis for back pain in adults is provided along with key historical and physical examination findings. The various therapeutic options are summarized with an emphasis on evidence-based findings. These reviewed treatments include medication, physical therapy, topical treatments, injections, and complementary and alternative medicine. The indications for surgery and specialty referral are also discussed. [Pt] Publication type: JOURNAL ARTICLE [Em] Entry month: 1305 [Js] Journal subset: IM [St] Status: In-Data-Review

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[PMID]: 23642857 [Au] Autor: Eagles D; Walker PJ; Zalucki MP; Durr PA [Ad] Address: CSIRO Animal, Food and Health Sciences, Australian Animal Health Laboratory, Geelong, VIC, Australia; School of Biological Sciences, The University of Queensland, Brisbane, QLD 4072, Australia. Electronic address: debbie.eagles@csiro.au. [Ti] Title: Modelling spatio-temporal patterns of long-distance Culicoides dispersal into northern Australia. [So] Source: Prev Vet Med;110(3-4):312-22, 2013 Jul 1. [Is] ISSN: 1873-1716 [Cp] Country of publication: Netherlands [La] Language: eng [Ab] Abstract: Novel arboviruses, including new serotypes of bluetongue virus, are isolated intermittently from cattle and insects in northern Australia. These viruses are thought to be introduced via windborne dispersal of Culicoides from neighbouring land masses to the north. We used the HYSPLIT particle dispersal model to simulate the spatio-temporal patterns of Culicoides dispersal into northern Australia from nine putative source sites across Indonesia, Timor-Leste and Papua New Guinea. Simulated dispersal was found to be possible from each site, with the islands of Timor and Sumba highlighted as the likely principal sources and February the predominant month of dispersal. The results of this study define the likely spatial extent of the source and arrival regions, the relative frequency of dispersal from the putative sources and the temporal nature of seasonal winds from source sites into arrival regions. Importantly, the methodology and results may be applicable to other insect and pathogen incursions into northern Australia. [Pt] Publication type: JOURNAL ARTICLE [Em] Entry month: 1305 [Js] Journal subset: IM [St] Status: In-Data-Review

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[PMID]: 23611065 [Au] Autor: Thomas D; Delgado A; Louison B; Lefrancois T; Shaw J [Ad] Address: Veterinary and Livestock Division, Ministry of Agriculture, Ministerial Complex, Tanteen St. George's, Grenada, WI, United States. Electronic address: dennisdthomas@yahoo.com. [Ti] Title: Examining dog owners' beliefs regarding rabies vaccination during government-funded vaccine clinics in Grenada to improve vaccine coverage rates. [So] Source: Prev Vet Med;110(3-4):563-9, 2013 Jul 1. [Is] ISSN: 1873-1716 [Cp] Country of publication: Netherlands [La] Language: eng [Ab] Abstract: Vaccination of domestic pets is an important component of rabies control and prevention in countries where the disease is maintained in a wildlife reservoir. In Grenada, vaccine coverage rates were low, despite extensive public education and advertising of government-sponsored vaccine clinics where rabies vaccine is administered to animals at no cost to animal owners. Information was needed on reasons for decreased dog owner participation in government-funded rabies vaccination clinics. A total of 120 dog owners from 6 different parishes were asked to complete a questionnaire assessing their currently held beliefs about rabies vaccination and perception of the risk posed by rabies. Over 70% of respondents believed that problems in the organization and management of clinic sites could allow for fighting between dogs or disease spread among dogs, while 35% of owners did not believe that they had the ability or adequate help to bring their dogs to the clinic sites. Recommendations for improving vaccine coverage rates included: improved scheduling of clinic sites and dates; increased biosecurity at clinic locations; focused advertising on the availability of home visits, particularly for aggressive dogs or dogs with visible skin-related diseases such as mange; and the recruitment of community volunteers to assist with bringing dogs to the clinic sites. [Pt] Publication type: JOURNAL ARTICLE [Em] Entry month: 1305 [Js] Journal subset: IM [St] Status: In-Data-Review

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[PMID]: 23561958 [Au] Autor: Mueller-Doblies D; Speed K; Davies RH [Ad] Address: Bacteriology Department, Animal Health and Veterinary Laboratories Agency Weybridge, New Haw, Addlestone, Surrey KT15 3NB, United Kingdom. Electronic address: doris.mueller-doblies@ahvla.gsi.gov.uk. [Ti] Title: A retrospective analysis of Salmonella serovars isolated from pigs in Great Britain between 1994 and 2010. [So] Source: Prev Vet Med;110(3-4):447-55, 2013 Jul 1. [Is] ISSN: 1873-1716 [Cp] Country of publication: Netherlands [La] Language: eng [Ab] Abstract: A retrospective study analysing Salmonella serovars and antimicrobial resistance data from pigs in Great Britain between 1994 and 2010 was performed. Data were obtained through scanning surveillance and compared with prevalence data from other livestock species as well as human data. During the study period, two serovars, S. Typhimurium and S. Derby, predominated in British pigs. The total number of Salmonella incidents has decreased steadily over the study period, from 360 incidents per year in 1994 to 172 incidents in 2010. S. Typhimurium has been the most common serovar every year, but the relative percentage went down over the past few years. During the same time period, monophasic strains of S. Typhimurium have increased in numbers and were accounting for as much as 25% of incidents in 2010, representing the second most common serovar in British pigs in 2010. Antimicrobial resistance data from S. Typhimurium isolates show that the percentage of isolates which are resistant to six or more antimicrobials has increased from 27.2% in 1994 to 58.3% in 2010 and that the percentage of isolates fully sensitive to the panel of antimicrobials tested was only 3.3% in 2010. S. Typhimurium isolates belonged mainly to phagetypes DT193 and U288 in 2010, and an increase can be seen in the number of isolates belonging to phage type DT193. DT104, which was the predominant phagetype during the 1990s, has gone down considerably and represented less than 5% of all S. Typhimurium isolates in 2010. Monophasic strains of S. Typhimurium belonged mainly to phagetype 193 with less than 20% belonging to phagetype 120. The overall trend shows that the number of Salmonella incidents reported from British pigs has gone down considerably over the 17-year study period, but that the relative percentage of monophasic strains of S. Typhimurium has increased significantly. This trend seems to be in line with observations from other European countries, where an increase of this serovar can be seen both in livestock and in human patients. The increasing percentage of Salmonella-isolates which show multi-resistance is a matter of concern and has to be monitored carefully in order to assess any potential risks this may pose to human patients. [Pt] Publication type: JOURNAL ARTICLE [Em] Entry month: 1305 [Js] Journal subset: IM [St] Status: In-Data-Review

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[PMID]: 23558033 [Au] Autor: Mateus-Pinilla N; Weng HY; Ruiz MO; Shelton P; Novakofski J [Ad] Address: Illinois Natural History Survey, University of Illinois Urbana-Champaign, 1816 S. Oak Street, Champaign, IL 61820, USA. Electronic address: nohram@illinois.edu. [Ti] Title: Evaluation of a wild white-tailed deer population management program for controlling chronic wasting disease in Illinois, 2003-2008. [So] Source: Prev Vet Med;110(3-4):541-8, 2013 Jul 1. [Is] ISSN: 1873-1716 [Cp] Country of publication: Netherlands [La] Language: eng [Ab] Abstract: We evaluated population management programs for controlling chronic wasting disease (CWD) in wild white-tailed deer in Illinois between November 2002 and March 2008. The intervention consisted of measures of deer removal from three deer population control programs: Illinois Department of Natural Resources culling, deer population control permits and nuisance deer removal permits. We included in the analysis a total of 14,650 white-tailed deer CWD test results. These data also included location and demographic data collected from both deer harvested in the interventions as well as deer from hunter harvests and deer vehicle collisions. We quantified intervention pressures as the number of years of intervention, the total number of deer removed and the average number of deer removed per year. We accounted for temporal and spatial variations of intervention by using mixed logistic regression to model the association between intervention pressures and CWD prevalence change. The results showed that deer population management intervention as practiced in Illinois during the study period was negatively associated with CWD prevalence and the strength of association varied depending on age of deer and the measure of intervention pressure. The population management programs showed a more consistent association with reduced CWD prevalence in fawn and yearling white-tailed deer than in adult deer. Our results also suggested that frequent and continuing intervention events with at least moderate intensity of culling were needed to reduce CWD prevalence. A longer study period, however, is needed to make a more definite conclusion about the effectiveness of similar population management programs for controlling CWD in wild white-tailed deer. [Pt] Publication type: JOURNAL ARTICLE [Em] Entry month: 1305 [Js] Journal subset: IM [St] Status: In-Data-Review

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