Database : MEDLINE
Search on : meningioma [Words]
References found : 20188 [refine]
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[PMID]: 29511686
[Au] Autor:Carlberg M; Koppel T; Ahonen M; Hardell L
[Ad] Address:Department of Oncology, Faculty of Medicine and Health, Örebro University, 701 82 Örebro, Sweden.
[Ti] Title:Case-Control Study on Occupational Exposure to Extremely Low-Frequency Electromagnetic Fields and the Association with Meningioma.
[So] Source:Biomed Res Int;2018:5912394, 2018.
[Is] ISSN:2314-6141
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Objective: Exposure to extremely low-frequency electromagnetic fields (ELF-EMF) was in 2002 classified as a possible human carcinogen, Group 2B, by the International Agency for Research on Cancer at WHO based on an increased risk for childhood leukemia. In case-control studies on brain tumors during 1997-2003 and 2007-2009 we assessed lifetime occupations in addition to exposure to different agents. The INTEROCC ELF-EMF Job-Exposure Matrix was used for associating occupations with ELF-EMF exposure ( T) with meningioma. Cumulative exposure ( T-years), average exposure ( T), and maximum exposed job ( T) were calculated. Results: No increased risk for meningioma was found in any category. For cumulative exposure in the highest exposure category 8.52+ T years odds ratio (OR) = 0.9, 95% confidence interval (CI) = 0.7-1.2, and linear trend = 0.45 were calculated. No statistically significant risks were found in different time windows. Conclusion: In conclusion occupational ELF-EMF was not associated with an increased risk for meningioma.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180311
[Lr] Last revision date:180311
[St] Status:In-Process
[do] DOI:10.1155/2018/5912394

  2 / 20188 MEDLINE  
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[PMID]: 29520612
[Au] Autor:Dudley RWR; Torok MR; Randall S; Béland B; Handler MH; Mulcahy-Levy JM; Liu AK; Hankinson TC
[Ad] Address:Division of Neurosurgery, Department of Pediatric Surgery, Montreal Children's Hospital, 1001 Decarie Boulevard, Montreal, QC, H4A-3J1, Canada. roy.dudley@mail.mcgill.ca.
[Ti] Title:Pediatric versus adult meningioma: comparison of epidemiology, treatments, and outcomes using the Surveillance, Epidemiology, and End Results database.
[So] Source:J Neurooncol;, 2018 Mar 09.
[Is] ISSN:1573-7373
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Pediatric meningiomas, which account for < 1% of all meningiomas, are thought to have unique features, including being more aggressive than their adult counterparts. The goal of this investigation was to compare pediatric and adult meningiomas in a large head-to-head comparison. We used the Surveillance, Epidemiology, and End Result (SEER) datasets to compare meningioma demographics, first treatments, and outcomes among children/adolescents (0-21 years), young adults (22-45 years), and older adults (> 45 years). During 2004-2012, SEER contained 59148 patients age 0-107 years diagnosed with meningioma, with children/adolescents accounting for 381 (0.64%) patients. Unlike older and young adults, children/adolescents with meningioma did not demonstrate female predominance, and had an equal 1:1 male-to-female ratio. Children/adolescents also had almost three-times as many spinal tumors (13.1%) than young adults (4.2%) and older adults (4.4%). Both children/adolescents and young adults had undergone more gross total resections (both 43%) versus older adults (25%), and were treated more with radiation (14.6%, and 12.0% respectively) than their older counterparts (8.5%). In addition, both children/adolescents and young adults had significantly lower all-cause mortality (4.5% in both) than older adults (24.6%), during median 35-month follow-up. Inherent limitations of the SEER datasets restrict our ability to answer important questions regarding comparisons of tumor grading, histological diagnosis, cause-specific mortality, and neurofibromatosis status. Pediatric meningiomas appear distinct from their adult counterparts as they do not display the typical female predominance and include more clinically relevant spinal tumors. More extensive surgeries, greater use of radiation therapy, and lower all-cause mortality were seen in both children/adolescents and young adults, which raises questions regarding the perceived uniquely aggressive nature of pediatric meningiomas. However, due to the significant limitations of the SEER datasets, our results must be interpreted cautiously and stand only to foster novel questions, which would be better answered in well-designed, prospective studies.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1007/s11060-018-2756-1

  3 / 20188 MEDLINE  
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[PMID]: 29518763
[Au] Autor:Angelousi A; Settas N; Faucz FR; Lyssikatos C; Quezado M; Nasiri-Ansari N; Stratakis CA; Kassi E
[Ad] Address:1st Department of Internal Medicine, Laiko Hospital, Medical School, National and Kapodistrian University of Athens, Greece, Section on Endocrinology & Genetics, Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD), National Insitutes of Health (NIH), Bethesd
[Ti] Title:Medullary thyroid cancer, leukemia, mesothelioma and meningioma associated with germline APC and RASAL1 variants: a new syndrome?
[So] Source:Hormones (Athens);16(4):423-428, 2017 Oct.
[Is] ISSN:1109-3099
[Cp] Country of publication:Greece
[La] Language:eng
[Ab] Abstract:Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor hereditary in 35% of cases. The most common syndromic form is in the context of the multiple endocrine neoplasia type 2 (MEN 2) syndromes in association with other tumors and due to germline RET mutations. We describe a 57-year-old female patient diagnosed with sporadic MTC. The patient had a history of other neoplasias, such as acute myeloid leukemia, for which she had received chemotherapy, and two other solid tumors, peritoneal mesothelioma and meningioma. Genetic analyses were carried out including whole exome and Sanger sequencing (WES and SS) and loss-of-heterozygosity (LOH) testing for the respective loci. Immunohistochemistry (IHC) was used for the detection of proteins of interest. WES showed two germline variants in the APC and RASAL1 genes confirmed by SS. In MTC tissue only there was a RETvariant identified by SS; germline studies did not show any RETsequence changes. The pattern of tumors in this patient is unusual for either one of the APC- orRASAL1-associated neoplasms and her non-MEN 2-associated MTC contained a RET variant like other sporadic MTCs. As in other patients with more than one genetic variant predisposing to tumors, it is possible that this case represents a unique association.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:In-Process
[do] DOI:10.14310/horm.2002.1763

  4 / 20188 MEDLINE  
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[PMID]: 29518711
[Au] Autor:Dobran M; Marini A; Nasi D; Liverotti V; Benigni R; Iacoangeli M; Scerrati M
[Ad] Address:Department of Neurosurgery, Umberto I General Hospital, Università Politecnica delle Marche, Ancona, Italy. Electronic address: dobran@libero.it.
[Ti] Title:Surgical treatment and outcome in patients over 80 years old with intracranial meningioma.
[So] Source:Clin Neurol Neurosurg;167:173-176, 2018 Feb 17.
[Is] ISSN:1872-6968
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:OBJECTIVE: Study of mortality rate and clinical outcomes in octogenarians patients operated for intracranial meningiomas. PATIENTS AND METHODS: Clinical, radiological and surgical data of 25 elderly patients aging over 80 years old operated at our Department from 2013 to 2016 for intracranial meningiomas have been recorded and analyzed. One-month mortality and clinical outcome at six-months after surgery were evaluated. Logistic regression was used for detecting the risk factors influencing mortality and neurological functions. RESULTS: The median age at diagnosis was 8185 years (range 80-87). Meningiomas were gross-total removed in 18 cases out of 25 (72%) and partially resected in 7 (28%). One-month post-operative mortality occurred in 2 pts out of 25 (8%). A close correlation was found between operative duration over 240 min and mortality (p = 0,0421). There was a significantly lower mortality in patients with ASA II rather than in patients with ASA III (p = 0,038). The median pre-operative KPS value was 743 (range 50-90) while at six-month follow-up was 82. The surgical time (p = 00,006) and size of the lesion >4 cm (p = 002) were a significant prognostic factors for clinical improvement at six-month follow-up. CONCLUSIONS: The operative time and the ASA score are the most important prognostic factors for the mortality and neurological outcome of elderly patients over 80 years old operated for intracranial meningioma. Even if the number of patients is limited, our findings suggest that, after a careful preoperative stratification in elderly patients, it is possible to remove an intracranial meningioma with good results.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:Publisher

  5 / 20188 MEDLINE  
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[PMID]: 29451149
[Au] Autor:Cheng X; Cheng JL; Gao AK
[Ad] Address:Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450000, China.
[Ti] Title:A Study on Clinical Characteristics and Magnetic Resonance Imaging Manifestations on Systemic Rosai-Dorfman Disease.
[So] Source:Chin Med J (Engl);131(4):440-447, 2018 Feb 20.
[Is] ISSN:0366-6999
[Cp] Country of publication:China
[La] Language:eng
[Ab] Abstract:Background:: Rosai-Dorfman disease (RDD) is typically characterized by painless bilateral and symmetrical cervical lymphadenopathy, with associated fever and leukocytosis. The aim of the current study was to summarize the clinical features and imaging characteristics of RDD, in an effort to improve its diagnostic accuracy. Methods: The study was analyzed from 32 patients between January 2011 and December 2017; of these, 16 patients had pathologically diagnosed RDD, eight had pathologically diagnosed meningioma, and eight pathologically diagnosed lymphoma. All patients underwent computed tomography and magnetic resonance imaging (MRI). Clinical features and imaging characteristics of RDD were analyzed retrospectively. The mean apparent diffusion coefficient (ADC) values of lesions at different sites were measured, and one-way analysis of variance and the least significant difference t-test were used to compare the differences between groups and draw receiver operating characteristic curves. The tumors were excised for biopsy and analyzed using immunohistochemistry. Results:: The mean ADCs were (0.81 ± 0.10) × 10 mm /s for intercranial RDD, (0.73 ± 0.05) × 10 mm /s for nasopharyngeal RDD, (0.74 ± 0.11) × 10 mm /s for bone RDD, and (0.71 ± 0.04) × 10 mm /s for soft-tissue RDD. The optimum ADC to distinguish intracranial RDD from lymphoma was 0.79 × 10 mm /s (62.5% sensitivity and 100% specificity) and to distinguish meningioma from intracranial RDD was 0.92 × 10 mm /s (62.5% sensitivity and 100% specificity). Levels of C-reactive protein, erythrocyte sediment rate and D-dimer were significantly elevated (81%, 87%, and 75%, respectively). On immunohistochemistry, RDD was positive for both S-100 and CD68 proteins but negative for CD1a. Conclusions:: Conventional MRI, combined with diffusion-weighted imaging and ADC mapping, is an important diagnostic tool in evaluating RDD patients. An accurate diagnosis of RDD should consider the clinical features, imaging characteristics, and the pathological findings.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:In-Process
[do] DOI:10.4103/0366-6999.225053

  6 / 20188 MEDLINE  
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[PMID]: 29516306
[Au] Autor:Frati A; Pesce A; Toccaceli G; Fraschetti F; Caruso R; Raco A
[Ad] Address:IRCCS "Neuromed" Neurosurgery Department, Sapienza University, Rome, Italy.
[Ti] Title:Spinal Meningiomas Prognostic Evaluation Score (SPES): predicting the neurological outcomes in spinal meningioma surgery.
[So] Source:Neurosurg Rev;, 2018 Mar 07.
[Is] ISSN:1437-2320
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:Among many factors leading to a worse functional prognosis in spinal meningioma (SM) surgery, in a previous study, we recognized anterior/anterolateral axial topography, sphincter involvement at first evaluation, surgery performed on a recurrence, and worse preoperative functional status. The purpose of this paper is to evaluate the cumulative weight of these factors on prognosis through a multinomial logistic regression model performed on an original evaluation scale designed by the authors on the ground of the experience of the neurosurgical departments of our University. The original SM database composed of 173 cases was classified in regard to sex, age, symptoms, axial and sagittal location, Simpson grade resection, and functional pre/postoperative status. Fine presurgical and follow-up reevaluations were available. The authors propose a scale (Spinal Meningiomas Prognostic Evaluation Score (SPES)) of preoperative evaluation to assess the surgery-related risk of neurological worsening experienced by the patients included in the present cohort. The authors describe a strong statistical association between the SPES and the follow-up Frankel and McCormick scores (r = - 460 and .441, p .001, both). Through a univariate ANOVA analysis, we disclosed that patients presenting scores 2 and 3 had a significantly higher association to lesser Frankel and McCormick postoperative scores, in respect to patients presenting SPES scores 0-1 (univariate ANOVA, p .008 and .011). Anterior or anterolateral axial location, operating on a recurrence of SM, sphincter involvement, and worse functional grade at onset present, along with the SPES scores are fairly predictive and reliable in respect to the long-term results of patients suffering from SM.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:Publisher
[do] DOI:10.1007/s10143-018-0961-1

  7 / 20188 MEDLINE  
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[PMID]: 29514297
[Au] Autor:Bendok B; Abi-Aad KR; Sattur MG; Welz ME; Hoxworth JM; Lal D
[Ad] Address:Department of Neurological Surgery, Mayo Clinic, Phoenix, Arizona.
[Ti] Title:Endoscopic Resection of a Paraclinoid Meningioma Extending Into the Optic Canal: 2-Dimensional Operative Video.
[So] Source:Oper Neurosurg (Hagerstown);, 2018 Mar 03.
[Is] ISSN:2332-4260
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180307
[Lr] Last revision date:180307
[St] Status:Publisher
[do] DOI:10.1093/ons/opy011

  8 / 20188 MEDLINE  
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[PMID]: 29514273
[Au] Autor:Cândido DNC; de Oliveira JG; Borba LAB
[Ad] Address:Department of Neurosurgery, Hospital Universitário Evangélico de Curitiba, Curitiba, Brazil.
[Ti] Title:Microsurgical Resection of Cavernous Sinus Meningioma: 2-Dimensional Operative Video.
[So] Source:Oper Neurosurg (Hagerstown);, 2018 Mar 03.
[Is] ISSN:2332-4260
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180307
[Lr] Last revision date:180307
[St] Status:Publisher
[do] DOI:10.1093/ons/opy019

  9 / 20188 MEDLINE  
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[PMID]: 29436365
[Au] Autor:Lang J; Czech T; Slavc I; Reisinger D; Bartsch S; Hainfellner JA; Haberler C; Gelpi E
[Ti] Title:Teaching Case 2-2018: Sclerosing myxopapillary ependymoma mimicking whorling-sclerosing meningioma.
[So] Source:Clin Neuropathol;37(2):51-52, 2018 Mar/Apr.
[Is] ISSN:0722-5091
[Cp] Country of publication:Germany
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:In-Process
[do] DOI:10.5414/NP301099

  10 / 20188 MEDLINE  
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[PMID]: 29300964
[Au] Autor:Grauvogel J; Masalha W; Heiland DH; Jarc N; Grauvogel TD; Scheiwe C
[Ad] Address:Department of Neurosurgery, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
[Ti] Title:Piezosurgery-A Safe Technique to Perform Lateral Suboccipital Craniotomy?
[So] Source:Oper Neurosurg (Hagerstown);, 2017 Dec 29.
[Is] ISSN:2332-4260
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: Piezosurgery (PS) is a relatively new technique based on microvibrations generated by the piezoelectric effect. It selectively cuts bone tissue and preserves the surrounding soft tissue. OBJECTIVE: To evaluate the use of PS for performing lateral suboccipital craniotomy. METHODS: PS was used to perform a lateral suboccipital craniotomy in 22 patients who underwent surgery for different cerebellopontine angle (CPA) pathologies in the neurosurgical department. The applicability of PS for lateral suboccipital craniotomy was evaluated with respect to safety, preciseness of bone cutting, and in particular the preservation of the adjacent dura and sigmoid and transverse sinuses. RESULTS: Lateral suboccipital craniotomy in 22 patients who underwent surgery for different CPA pathologies (13 vestibular schwannoma, 5 petrous bone meningioma, 1 petroclival meningioma, 2 epidermoid cysts, and 1 petrous bone cholesterol granuloma) was performed with PS without any complications. A burr hole was set before piezosurgical craniotomy in 6 patients, with no prior burr hole in 16 patients. Incidental durotomy during piezosurgical craniotomy occurred in 6 patients, and small lacerations of the sigmoid sinus caused by the piezosurgical device were observed in 3 patients. CONCLUSION: Although PS is a safe and selective bone cutting technique that preserves the surrounding soft tissue, it can still lead to unintended dural tears during lateral suboccipital craniotomy. This must be kept in mind when using PS for craniotomies and relying on the selective bone cutting properties of PS.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:Publisher
[do] DOI:10.1093/ons/opx272


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