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[PMID]: 28955348
[Au] Autor:Yang Z; Ji Y
[Ad] Address:Key Laboratory for Plant Diversity and Biogeography of East Asia, Kunming Institute of Botany, Chinese Academy of SciencesKunming, China.
[Ti] Title:Comparative and Phylogenetic Analyses of the Complete Chloroplast Genomes of Three Arcto-Tertiary Relicts: , , and .
[So] Source:Front Plant Sci;8:1536, 2017.
[Is] ISSN:1664-462X
[Cp] Country of publication:Switzerland
[La] Language:eng
[Ab] Abstract:The Arcto-Tertiary relict genera, , , and represent deep lineages in the asterid order Cornales. Recent phylogenetic studies suggested that these genera should be placed in a newly circumscribed family, Nyssaceae. However, because these analyses were based upon a few genes, it is prudent and necessary to examine further evidence before adopting this taxonomic treatment. In this study, we determined the complete chloroplast (cp) genomes of , , and . Their cp genomes ranged from 156,672 to 158,409 bp, which included 115 genes, and their genome features were highly similar to those of other species within the order Cornales. The phylogenetic relationships among the genera , , , and 23 related taxa in the asterids were analyzed based on 73 protein-coding genes from the cp genomes. All of the previously recognized major clades (namely Cornales, Ericales, Campanulids, and Lamiids) in the asterids, as well as their relationships, were recovered with robust support. A clade including the genera , , , and , was resolved as a well-supported monophyletic group, which was fully separated from the family Cornaceae by the family Hydrangeaceae. Our results provide novel evidence to support the acceptance of the family Nyssaceae outlined by the updated Angiosperm Phylogeny Group.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1709
[Cu] Class update date: 171001
[Lr] Last revision date:171001
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.3389/fpls.2017.01536

  2 / 30 MEDLINE  
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[PMID]: 27068221
[Au] Autor:Li M; Dong X; Peng J; Xu W; Ren R; Liu J; Cao F; Liu Z
[Ad] Address:Key Laboratory of Cultivation and Protection for Non-wood Forest Trees, Ministry of Education, College of Life Science and Technology; Central South University of Forestry and Technology, Changsha, People's Republic of China.
[Ti] Title:De novo transcriptome sequencing and gene expression analysis reveal potential mechanisms of seed abortion in dove tree (Davidia involucrata Baill.).
[So] Source:BMC Plant Biol;16:82, 2016 Apr 12.
[Is] ISSN:1471-2229
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Dove tree (Davidia involucrata Baill.) is a rare and endangered species. Natural reproduction of dove tree is extremely difficult due to its low fecundity. Serious seed abortion is one of the key factors restraining its sexual reproduction. Understanding the inducements of seed abortion is critical for addressing the issue of offspring production and the survivability of such an endangered species. However, studies on the molecular mechanism of seed abortion in woody plants are lacking, and the dearth of genomic resources for dove tree restricts further research. RESULTS: In this study, using the Illumina platform, we performed de novo transcriptome sequencing of the fruit and seed in dove tree. A total of 149,099 transcripts were isolated and then assembled into 72,885 unigenes. Subsequently, differentially expressed genes (DEGs) between normal and abortive seeds were screened. Genes involved in response to stress, hormone signal transduction, programmed cell death, lignin biosynthesis, and secondary cell wall biogenesis showed significant different expression levels between normal and abortive seeds. CONCLUSION: Combined results indicated that the abortive seeds were under the adversity stress, which should be controlled by the maternal plant. Maternally controlled development of integument is assumed to be a critical process for abortion regulation. MYB and WRKY transcription factors, receptor kinase and laccase are considered to be important regulators in seed abortion. Moreover, mass sequence data facilitated further molecular research on this unique species.
[Mh] MeSH terms primary: Gene Expression Profiling/methods
Gene Expression Regulation, Plant
Nyssaceae/genetics
Seeds/genetics
Transcriptome
[Mh] MeSH terms secundary: Apoptosis/genetics
Cell Proliferation/genetics
Cluster Analysis
DNA Replication/drug effects
Endangered Species
Fatty Acids/metabolism
Fertility/genetics
Fruit/genetics
Gene Ontology
Nyssaceae/cytology
Nyssaceae/metabolism
Plant Infertility/genetics
Reverse Transcriptase Polymerase Chain Reaction
Seeds/cytology
Seeds/metabolism
Sequence Analysis, RNA/methods
Starch/metabolism
Sucrose/metabolism
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Name of substance:0 (Fatty Acids); 57-50-1 (Sucrose); 9005-25-8 (Starch)
[Em] Entry month:1612
[Cu] Class update date: 170220
[Lr] Last revision date:170220
[Js] Journal subset:IM
[Da] Date of entry for processing:160413
[St] Status:MEDLINE
[do] DOI:10.1186/s12870-016-0772-x

  3 / 30 MEDLINE  
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[PMID]: 25924840
[Au] Autor:Tong SM; Feng MG
[Ad] Address:Institute of Microbiology, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China.
[Ti] Title:Laboratory and field evaluations of camptothecin sodium salt against phytophagous mites.
[So] Source:Pest Manag Sci;72(3):629-36, 2016 Mar.
[Is] ISSN:1526-4998
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Camptothecin (CPT), a monoterpene indole alkaloid from Camptotheca acuminate (Nyssaceae), is toxic to some insect pests but insoluble in water. Here we show that an aqueous CPT-Na(+) solution can kill the phytophagous mites Tetranychus urticae (TU), Acaphylla theae (AT) and Brevipalpus obovatus (BO) under laboratory and field conditions. RESULTS: Modelling of 10 day time-concentration-mortality responses of female adults to 2 mL tower sprays of three CPT-Na(+) dilutions generated LC50 and LT50 values that decreased over post-spray days and sprayed amounts respectively. CPT-Na(+) sprays required to kill 50% BO, TU and AT were 35, 41 and 124 µg mL(-1) on day 1 post-spray, but rapidly decreased to 2.2, 2.5 and 3.6 µg mL(-1) on day 5, and to 0.69, 0.77 and 1.17 µg mL(-1) on day 7 respectively. In summer field trials, a spray rate of 7.5 g CPT-Na(+) ha(-1) provided better control efficacy against TU (81-85%) on cotton or AT (90-93%) and BO (83-88%) in tea gardens than aramite (commercial acaricide) at the labelled rate of 56.25 g ha(-1) . Half of the CPT-Na(+) rate controlled the mites as effectively as aramite. CONCLUSION: Water-soluble CPT-Na(+) is a promising plant-sourced acaricide to combat wide-spectrum pest mites.
[Mh] MeSH terms primary: Acaricides
Camptothecin
Mites
[Mh] MeSH terms secundary: Animals
Female
Lethal Dose 50
Mites/growth & development
Nymph/growth & development
Sodium
Tetranychidae/growth & development
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Name of substance:0 (Acaricides); 9NEZ333N27 (Sodium); XT3Z54Z28A (Camptothecin)
[Em] Entry month:1610
[Cu] Class update date: 161230
[Lr] Last revision date:161230
[Js] Journal subset:IM
[Da] Date of entry for processing:150501
[St] Status:MEDLINE
[do] DOI:10.1002/ps.4033

  4 / 30 MEDLINE  
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[PMID]: 25431576
[Au] Autor:Jerominek M; Bull-Hereñu K; Arndt M; Claßen-Bockhoff R
[Ad] Address:Institut für Spezielle Botanik, Johannes Gutenberg-Universität Mainz, Germany.
[Ti] Title:Live imaging of developmental processes in a living meristem of Davidia involucrata (Nyssaceae).
[So] Source:Front Plant Sci;5:613, 2014.
[Is] ISSN:1664-462X
[Cp] Country of publication:Switzerland
[La] Language:eng
[Ab] Abstract:Morphogenesis in plants is usually reconstructed by scanning electron microscopy and histology of meristematic structures. These techniques are destructive and require many samples to obtain a consecutive series of states. Unfortunately, using this methodology the absolute timing of growth and complete relative initiation of organs remain obscure. To overcome this limitation, an in vivo observational method based on Epi-Illumination Light Microscopy (ELM) was developed and tested with a male inflorescence meristem (floral unit) of the handkerchief tree Davidia involucrata Baill. (Nyssaceae). We asked whether the most basal flowers of this floral unit arise in a basipetal sequence or, alternatively, are delayed in their development. The growing meristem was observed for 30 days, the longest live observation of a meristem achieved to date. The sequence of primordium initiation indicates a later initiation of the most basal flowers and not earlier or simultaneously as SEM images could suggest. D. involucrata exemplarily shows that live-ELM gives new insights into developmental processes of plants. In addition to morphogenetic questions such as the transition from vegetative to reproductive meristems or the absolute timing of ontogenetic processes, this method may also help to quantify cellular growth processes in the context of molecular physiology and developmental genetics studies.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1411
[Cu] Class update date: 170220
[Lr] Last revision date:170220
[Da] Date of entry for processing:141129
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.3389/fpls.2014.00613

  5 / 30 MEDLINE  
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[PMID]: 22539515
[Au] Autor:Du YJ; Dai QY; Zhang LY; Qiu YX; Li JH; Fu CX
[Ad] Address:Key Laboratory of Conservation Biology for Endangered Wildlife of the Ministry of Education, and College of Life Sciences, Zhejiang University, Hangzhou, China.
[Ti] Title:Development of microsatellite markers for the dove tree, Davidia involucrata (Nyssaceae), a rare endemic from China.
[So] Source:Am J Bot;99(5):e206-9, 2012 May.
[Is] ISSN:1537-2197
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:PREMISE OF THE STUDY: Microsatellite primers were developed for the endangered Davidia involucrata to assess the population genetics and infer its evolutionary history. METHODS AND RESULTS: Using both the modified magnetic bead hybridization method and the dual-suppression PCR method, we isolated and characterized 12 polymorphic microsatellite loci using 134 individuals from five populations in southwestern China. The number of alleles per locus ranged from six to 21 (mean = 10.8). The expected heterozygosity per locus ranged from 0.404 to 0.918 and observed heterozygosity ranged from 0.015 to 0.821. CONCLUSIONS: All of the 12 microsatellite markers developed for D. involucrata are polymorphic, and lay a solid foundation for further studies of the population genetics of this famous tree.
[Mh] MeSH terms primary: Microsatellite Repeats/genetics
Nyssaceae/genetics
Trees/genetics
[Mh] MeSH terms secundary: China
Genetic Loci/genetics
Genetics, Population
Molecular Sequence Data
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Entry month:1305
[Cu] Class update date: 120502
[Lr] Last revision date:120502
[Js] Journal subset:IM
[Da] Date of entry for processing:120428
[St] Status:MEDLINE
[do] DOI:10.3732/ajb.1100507

  6 / 30 MEDLINE  
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[PMID]: 22283650
[Au] Autor:Mollica A; Stefanucci A; Feliciani F; Cacciatore I; Cornacchia C; Pinnen F
[Ad] Address:Dipartimento di Scienze del Farmaco, Università di Chieti-Pescara G. d'Annunzio, Via dei Vestini 31, 66100 Chieti, Italy. a.mollica@unich.it
[Ti] Title:Delivery methods of camptothecin and its hydrosoluble analogue irinotecan for treatment of colorectal cancer.
[So] Source:Curr Drug Deliv;9(2):122-31, 2012 Mar.
[Is] ISSN:1875-5704
[Cp] Country of publication:United Arab Emirates
[La] Language:eng
[Ab] Abstract:Camptothecins are a family of alkaloids originally extracted from the Chinese tree Camptotheca acuminata, Nyssaceae, exhibiting a strong activity against colorectal cancer (CRC). CRC is a common malignancy worlwide. Despite significant developments in the treatment of this disease, it still causes considerable morbidity and mortality. Recent advances include both newer cytotoxic chemotherapies and novel biological agents including the more hydrosoluble camptothecin derivative, namely irinotecan. Camptothecin and irinotecan are selective human topoisomerase I inhibitors but their application for curing CRC is compromised by their intrinsic high toxicity, insolubility and instability. Furthermore, pharmacology studies have determined that continuously and prolonged schedules of administration are required. The aim of this work is to review the state of the art of camptothecin and its derivative irinotecan's delivery methods.
[Mh] MeSH terms primary: Antineoplastic Agents, Phytogenic/administration & dosage
Camptothecin/analogs & derivatives
Camptothecin/administration & dosage
Colorectal Neoplasms/drug therapy
[Mh] MeSH terms secundary: Humans
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Nm] Name of substance:0 (Antineoplastic Agents, Phytogenic); 7673326042 (irinotecan); XT3Z54Z28A (Camptothecin)
[Em] Entry month:1209
[Cu] Class update date: 171116
[Lr] Last revision date:171116
[Js] Journal subset:IM
[Da] Date of entry for processing:120131
[St] Status:MEDLINE

  7 / 30 MEDLINE  
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[PMID]: 21992614
[Au] Autor:Vekemans D; Viaene T; Caris P; Geuten K
[Ad] Address:Department of Biology, Katholieke Universiteit Leuven (K.U.Leuven), Kasteelpark Arenberg 31, 3001 Leuven, Belgium.
[Ti] Title:Transference of function shapes organ identity in the dove tree inflorescence.
[So] Source:New Phytol;193(1):216-28, 2012 Jan.
[Is] ISSN:1469-8137
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:• An important evolutionary mechanism shaping the biodiversity of flowering plants is the transfer of function from one plant organ to another. To investigate whether and how transference of function is associated with the remodeling of the floral organ identity program we studied Davidia involucrata, a species with conspicuous, petaloid bracts subtending a contracted inflorescence with reduced flowers. • A detailed ontogeny enabled the interpretation of expression patterns of B-, C- and E-class homeotic MADS-box genes using qRT-PCR and in situ hybridization techniques. We investigated protein-protein interactions using yeast two-hybrid assays. • Although loss of organs does not appear to have affected organ identity in the retained organs of the reduced flowers of D. involucrata, the bracts express the B-class TM6 (Tomato MADS box gene 6) and GLOBOSA homologs, but not DEFICIENS, and the C-class AGAMOUS homolog, representing a subset of genes also involved in stamen identity. • Our results may illustrate how petal identity can be partially transferred outside the flower by expressing a subset of stamen identity genes. This adds to the molecular mechanisms explaining the diversity of plant reproductive morphology.
[Mh] MeSH terms primary: Inflorescence/anatomy & histology
Nyssaceae/anatomy & histology
Trees/anatomy & histology
[Mh] MeSH terms secundary: Chlorophyll/metabolism
Cloning, Molecular
DNA, Complementary/genetics
Gene Expression Regulation, Developmental
Gene Expression Regulation, Plant
Genes, Plant/genetics
In Situ Hybridization
Inflorescence/cytology
Inflorescence/growth & development
Inflorescence/ultrastructure
MADS Domain Proteins/genetics
MADS Domain Proteins/metabolism
Molecular Sequence Data
Nyssaceae/cytology
Nyssaceae/genetics
Nyssaceae/ultrastructure
Organ Specificity
Plant Epidermis/cytology
Plant Epidermis/ultrastructure
Plant Proteins/genetics
Plant Proteins/metabolism
Protein Binding
Reproduction/genetics
Reverse Transcriptase Polymerase Chain Reaction
Trees/cytology
Trees/genetics
Trees/ultrastructure
Two-Hybrid System Techniques
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Name of substance:0 (DNA, Complementary); 0 (MADS Domain Proteins); 0 (Plant Proteins); 1406-65-1 (Chlorophyll)
[Em] Entry month:1204
[Cu] Class update date: 111205
[Lr] Last revision date:111205
[Js] Journal subset:IM
[Da] Date of entry for processing:111014
[St] Status:MEDLINE
[do] DOI:10.1111/j.1469-8137.2011.03915.x

  8 / 30 MEDLINE  
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[PMID]: 22035094
[Au] Autor:Sun Y; Luo H; Li Y; Sun C; Song J; Niu Y; Zhu Y; Dong L; Lv A; Tramontano E; Chen S
[Ad] Address:The Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, PR China.
[Ti] Title:Pyrosequencing of the Camptotheca acuminata transcriptome reveals putative genes involved in camptothecin biosynthesis and transport.
[So] Source:BMC Genomics;12:533, 2011 Oct 30.
[Is] ISSN:1471-2164
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Camptotheca acuminata is a Nyssaceae plant, often called the "happy tree", which is indigenous in Southern China. C. acuminata produces the terpenoid indole alkaloid, camptothecin (CPT), which exhibits clinical effects in various cancer treatments. Despite its importance, little is known about the transcriptome of C. acuminata and the mechanism of CPT biosynthesis, as only few nucleotide sequences are included in the GenBank database. RESULTS: From a constructed cDNA library of young C. acuminata leaves, a total of 30,358 unigenes, with an average length of 403 bp, were obtained after assembly of 74,858 high quality reads using GS De Novo assembler software. Through functional annotation, a total of 21,213 unigenes were annotated at least once against the NCBI nucleotide (Nt), non-redundant protein (Nr), Uniprot/SwissProt, Kyoto Encyclopedia of Genes and Genomes (KEGG), and Arabidopsis thaliana proteome (TAIR) databases. Further analysis identified 521 ESTs representing 20 enzyme genes that are involved in the backbone of the CPT biosynthetic pathway in the library. Three putative genes in the upstream pathway, including genes for geraniol-10-hydroxylase (CaPG10H), secologanin synthase (CaPSCS), and strictosidine synthase (CaPSTR) were cloned and analyzed. The expression level of the three genes was also detected using qRT-PCR in C. acuminata. With respect to the branch pathway of CPT synthesis, six cytochrome P450s transcripts were selected as candidate transcripts by detection of transcript expression in different tissues using qRT-PCR. In addition, one glucosidase gene was identified that might participate in CPT biosynthesis. For CPT transport, three of 21 transcripts for multidrug resistance protein (MDR) transporters were also screened from the dataset by their annotation result and gene expression analysis. CONCLUSION: This study produced a large amount of transcriptome data from C. acuminata by 454 pyrosequencing. According to EST annotation, catalytic features prediction, and expression analysis, novel putative transcripts involved in CPT biosynthesis and transport were discovered in C. acuminata. This study will facilitate further identification of key enzymes and transporter genes in C. acuminata.
[Mh] MeSH terms primary: Camptotheca/genetics
Camptothecin/biosynthesis
Transcriptome
[Mh] MeSH terms secundary: Camptotheca/enzymology
Cloning, Molecular
DNA, Plant/genetics
Expressed Sequence Tags
Gene Library
Genes, Plant
Molecular Sequence Annotation
Sequence Analysis, DNA
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Name of substance:0 (DNA, Plant); XT3Z54Z28A (Camptothecin)
[Em] Entry month:1204
[Cu] Class update date: 170220
[Lr] Last revision date:170220
[Js] Journal subset:IM
[Da] Date of entry for processing:111101
[St] Status:MEDLINE
[do] DOI:10.1186/1471-2164-12-533

  9 / 30 MEDLINE  
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[PMID]: 21300164
[Au] Autor:Xiang QY; Thomas DT; Xiang QP
[Ad] Address:Department of Plant Biology, North Carolina State University, Raleigh, NC 27695, USA. jenny_xiang@ncsu.edu
[Ti] Title:Resolving and dating the phylogeny of Cornales--Effects of taxon sampling, data partitions, and fossil calibrations.
[So] Source:Mol Phylogenet Evol;59(1):123-38, 2011 Apr.
[Is] ISSN:1095-9513
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:The order Cornales descends from the earliest split in the Asterid clade of flowering plants. Despite a few phylogenetic studies, relationships among families within Cornales remain unclear. In the present study, we increased taxon and character sampling to further resolve the relationships and to date the early diversification events of the order. We conducted phylogenetic analyses of sequence data from 26S rDNA and six chloroplast DNA (cpDNA) regions using parsimony (MP), maximum likelihood (ML), and Bayesian inference (BI) methods with different partition models and different data sets. We employed relaxed, uncorrelated molecular clocks on BEAST to date the phylogeny and examined the effects of different taxon sampling, fossil calibration, and data partitions. Our results from ML and BI analyses of the combined cpDNA sequences and combined cpDNA and 26S rDNA data suggested the monophyly of each family and the following familial relationships ((Cornaceae-Alangiaceae)-(Curtisiaceae-Grubbiaceae))-(((Nyssaceae-Davidiaceae)-Mastixiaceae)-((Hydrostachyaceae-(Hydrangeaceae-Loasaceae))). These relationships were strongly supported by posterior probability and bootstrap values, except for the sister relationship between the N-D-M and H-H-L clades. The 26S rDNA data and some MP trees from cpDNA and total evidence suggested some alternative alignments for Hydrostachyaceae within Cornales, but results of SH tests indicated that these trees were significantly worse explanations of the total data. Phylogenetic dating with simultaneous calibration of multiple nodes suggested that the crown group of Cornales originated around the middle Cretaceous and rapidly radiated into several major clades. The origins of most families dated back to the late Cretaceous except for Curtisiaceae and Grubbiaceae which may have diverged in the very early Tertiary. We found that reducing sampling density within families and analyzing partitioned data sets from coding and noncoding cpDNA, 26S rDNA, and combined data sets produced congruent estimation of divergence times, but reducing the number and changing positions of calibration points resulted in very different estimations.
[Mh] MeSH terms primary: Cornaceae/genetics
Fossils
[Mh] MeSH terms secundary: Bayes Theorem
Calibration
Chloroplasts/genetics
Cornaceae/classification
Data Interpretation, Statistical
Genetic Speciation
Likelihood Functions
Models, Genetic
Molecular Sequence Data
Phylogeny
RNA, Ribosomal/genetics
Sequence Analysis, DNA
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Nm] Name of substance:0 (RNA, Ribosomal); 0 (RNA, ribosomal, 26S)
[Em] Entry month:1108
[Cu] Class update date: 110322
[Lr] Last revision date:110322
[Js] Journal subset:IM
[Da] Date of entry for processing:110209
[St] Status:MEDLINE
[do] DOI:10.1016/j.ympev.2011.01.016

  10 / 30 MEDLINE  
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[PMID]: 21038296
[Au] Autor:Ding T; Jiang T; Zhou J; Xu L; Gao ZM
[Ad] Address:School of Plant Protection, Anhui Agricultural University, Hefei, China.
[Ti] Title:Evaluation of antimicrobial activity of endophytic fungi from Camptotheca acuminata (Nyssaceae).
[So] Source:Genet Mol Res;9(4):2104-12, 2010 Oct 26.
[Is] ISSN:1676-5680
[Cp] Country of publication:Brazil
[La] Language:eng
[Ab] Abstract:Agricultural research of plant-derived endophytic fungi has grown in recent decades. We isolated 26 endophytic fungi from the leaves, stems and fruits of "the tree of life", Camptotheca acuminata, and tested them for antimicrobial activities based on growth inhibition measurements in a modified agar diffusion method. Fermentation broths from most of the isolates exhibited antifungal activity and 50% exhibited antibacterial activity; some of them also exhibited strong broad-spectrum antimicrobial activity. The strongest antimicrobial activity was exhibited by strains XSY10 and XSY15 against Rhizoctonia solani and Fusarium oxysporum f. sp. vasinfectum, with 75% and 67% inhibition, respectively. Strain XSJ01 gave strong activity against pathogenic bacteria, with inhibition zones more than 20 mm in diameter. The isolates were identified by molecular methods as belonging to nine taxa: Nigrospora, Diaporthe, Alternaria, Colletotrichum, Pestalotiopsis, Sordariomycete, Guignardiai, Penicillium, and Zythia. Based on these results, we conclude that the endophytic fungi of C. acuminata are promising sources of novel bioactive compounds.
[Mh] MeSH terms primary: Anti-Infective Agents/pharmacology
Camptotheca/microbiology
Fungi/chemistry
[Mh] MeSH terms secundary: Anti-Infective Agents/isolation & purification
Base Sequence
Culture Media
DNA Primers
Fermentation
Microbial Sensitivity Tests
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Name of substance:0 (Anti-Infective Agents); 0 (Culture Media); 0 (DNA Primers)
[Em] Entry month:1102
[Cu] Class update date: 101101
[Lr] Last revision date:101101
[Js] Journal subset:IM
[Da] Date of entry for processing:101102
[St] Status:MEDLINE
[do] DOI:10.4238/vol9-4gmr809


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