Database : MEDLINE
Search on : postpericardiotomy and syndrome [Words]
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[PMID]: 29336245
[Au] Autor:Lazaros G; Imazio M; Brucato A; Vlachopoulos C; Lazarou E; Vassilopoulos D; Tousoulis D
[Ad] Address:First Cardiology Department, Hippokration General Hospital, National and Kapodistrian University of Athens. Greece.
[Ti] Title:The role of colchicine in pericardial syndromes.
[So] Source:Curr Pharm Des;, 2018 Jan 15.
[Is] ISSN:1873-4286
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:BACKGROUND: Colchicine is an old drug originally employed for the treatment of inflammatory disorders such as acute gout and familiar Mediterranean fever. METHODS: In the past few decades, colchicine has been at the forefront of the pharmacotherapy of several cardiac diseases, including acute and recurrent pericarditis, coronary artery disease, prevention of atrial fibrillation and heart failure. In this review, we have summarized the current evidence based medicine and guidelines recommendations in the specific context of pericardial syndromes. RESULTS: Colchicine has been firstly engaged in the treatment of recurrent pericarditis of viral, idiopathic and autoimmune origin. Shortly thereafter colchicine use has been expanded to the primary prevention of recurrences in patients with a first episode of pericarditis depicting similarly good results. The acquisition of high quality scientific data in the course of time from prospective randomized placebo-controlled trials and metanalyses have established colchicine as first line treatment option in acute and recurrent pericarditis, on top of the conventional treatment. The only concerns related to the use of colchicine are the side effects (mainly gastrointestinal intolerance) which although generally not serious, may account for treatment withdrawal in some cases. CONCLUSIONS: Colchicine has been established as a first line medication in the treatment of acute (first episode) and recurrent pericarditis on top of the conventional treatment as well as for the prevention of postpericardiotomy syndrome. It depicts a good safety profile with gastrointestinal intolerance being the most common side effect.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180116
[Lr] Last revision date:180116
[St] Status:Publisher
[do] DOI:10.2174/1381612824666180116101823

  2 / 394 MEDLINE  
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[PMID]: 29205989
[Au] Autor:Lehto J; Virolainen J
[Ti] Title:Postpericardiotomy syndrome.
[So] Source:Duodecim;133(4):411-6, 2017.
[Is] ISSN:0012-7183
[Cp] Country of publication:Finland
[La] Language:eng
[Ab] Abstract:Postpericardiotomy syndrome (PPS) is a common complication following cardiac surgery. In most cases it develops 2 to 3 weeks after the operation. An inflammatory reaction develops in the pericardium or pleural space with fever, chest pain and dyspnea as typical symptoms. The disease process is usually self-limiting. At present, the etiology is unknown, but an immunological mechanism is suspected as the cause of the disease. The incidence of PPS is essentially dependent on diagnostic criteria, patient group and type of operation. Treatment is carried out with anti-inflammatory analgesics, combined with colchicine in more severe cases.
[Mh] MeSH terms primary: Anti-Inflammatory Agents, Non-Steroidal/therapeutic use
Colchicine/therapeutic use
Postpericardiotomy Syndrome/diagnosis
Postpericardiotomy Syndrome/drug therapy
Tubulin Modulators/therapeutic use
[Mh] MeSH terms secundary: Diagnosis, Differential
Humans
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Nm] Name of substance:0 (Anti-Inflammatory Agents, Non-Steroidal); 0 (Tubulin Modulators); SML2Y3J35T (Colchicine)
[Em] Entry month:1801
[Cu] Class update date: 180108
[Lr] Last revision date:180108
[Js] Journal subset:IM
[Da] Date of entry for processing:171206
[St] Status:MEDLINE

  3 / 394 MEDLINE  
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[PMID]: 28971640
[Au] Autor:Dechtman ID; Grossman C; Shinar Y; Cohen R; Nachum E; Raanani E; Livneh A; Ben-Zvi I
[Ad] Address:Department of Internal Medicine F, Sheba Medical Center, Tel Hashomer, Israel.
[Ti] Title:Carriage of Mediterranean Fever (MEFV) Mutations in Patients with Postpericardiotomy Syndrome (PPS).
[So] Source:Isr Med Assoc J;19(9):562-565, 2017 Sep.
[Is] ISSN:1565-1088
[Cp] Country of publication:Israel
[La] Language:eng
[Ab] Abstract:BACKGROUND: Postpericardiotomy syndrome (PPS) is characterized by pleuro-pericardial inflammation, which occurs in patients undergoing surgical procedures involving the pleura, pericardium, or both. The syndrome is considered to be immune mediated. However, its pathogenesis is not fully understood. It has previously been demonstrated that the Mediterranean Fever (MEFV) gene, which is associated with familial Mediterranean fever (FMF), has a role in the activation and expression of several inflammatory diseases. OBJECTIVES: To investigate whether carriage of the MEFV mutation may precipitate PPS or affect its phenotype. METHODS: The study population included 45 patients who underwent cardiac surgery and developed PPS. The control group was comprised of 41 patients who did not develop PPS. Clinical and demographic data was collected. The severity of PPS was evaluated. Genetic analysis to determine the carriage of one the three most common MEFV gene mutations (M694V, V726A, E148Q) was performed. The carriage rate of MEFV mutations in patients with and without PPS was compared. Association between MEFV mutation carriage and severity of PPS was evaluated. RESULTS: The rate of mutation carriage in the MEFV gene was similar in patients with and without PPS (15.6% in the study groups vs. 29.3% in the control group, P = 0.1937). The rate of mutation carriage in the MEFV gene was significantly lower among patients with severe PPS as compared to patients with mild-moderate PPS (4.8% vs. 25%, P < 0.05). CONCLUSIONS: Carriage of mutations in the MEFV gene is not associated with development of PPS; however, it may affect PPS severity.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171003
[Lr] Last revision date:171003
[St] Status:In-Process

  4 / 394 MEDLINE  
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[PMID]: 28968307
[Au] Autor:Miller AF; Levy JA; Rempell RG; Nagler J
[Ad] Address:From the *Division of Emergency Medicine, Boston Children's Hospital; and †Department of Pediatrics, Harvard Medical School, Boston, MA.
[Ti] Title:Point-of-Care Ultrasound to Diagnose Postpericardiotomy Syndrome in a Child.
[So] Source:Pediatr Emerg Care;33(10):700-702, 2017 Oct.
[Is] ISSN:1535-1815
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:We report a case of a patient presenting with abdominal pain after cardiac surgery who was noted on point-of-care ultrasound (POCUS) to have pericardial and pleural effusion, in addition to ascites. The most notable findings were pleural and pericardial effusions, which combined with symptomatology met criteria for postpericardiotomy syndrome. Point-of-care ultrasound expedited the diagnosis of a pericardial effusion with impending tamponade and transfer for pericardiocentesis and placement of pericardial drain.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171002
[Lr] Last revision date:171002
[St] Status:In-Process
[do] DOI:10.1097/PEC.0000000000001271

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[PMID]: 28737876
[Au] Autor:Palanca Arias D; Corella Aznar EG; Ayerza Casas A; Fernández Gómez A; López Ramón M; Jiménez Montañés L
[Ad] Address:Hospital Infantil Miguel Servet, Zaragoza, Unidad de Cardiología Pediátrica, Unidad de Cuidados Intensivos Pediátricos. danielpalanca@hotmail.com.
[Ti] Title:Pericarditis aguda complicada con derrame pericárdico. Caso clínico pediátrico. [Acute pericarditis, complicated by pericardial effusion in a pediatric patient: case report].
[So] Source:Arch Argent Pediatr;115(4):e237-e242, 2017 Aug 01.
[Is] ISSN:1668-3501
[Cp] Country of publication:Argentina
[La] Language:spa
[Ab] Abstract:Acute pericarditis is the most common disease of the pericardium encountered in clinical practice. It is diagnosed in 0.1% of all admissions and 5% of emergency room admissions for chest pain. In developed countries, it is usually due to a benign cause. Idiopathic and infectious pericarditis are more common than secondary to surgical pericardiotomy or neoplastic causes, whereas tuberculosis is the dominant cause in developing countries. The most common symptoms of pericarditis are characteristic chest pain and fever. Since pericarditis presents a benign outcome because of self-limiting and good response to conventional anti-inflammatory therapy, it can be safely managed on outpatient basis unless a specific cause is suspected or the patient has high-risk features to avoid complications such as pericardial effusion, cardiac tamponade or recurrent pericarditis. We report a case of pericarditis, diagnosed 9 months after surgical closure of an atrial septal defect, in a 7-year-old boy with favorable evolution.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1707
[Cu] Class update date: 170724
[Lr] Last revision date:170724
[St] Status:In-Process
[do] DOI:10.5546/aap.2017.e237

  6 / 394 MEDLINE  
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[PMID]: 28575568
[Au] Autor:Vnukov VV; Sidorov RV; Milutina NP; Ananyan AA; Gvaldin DY; Sagakyants AB; Shlyk IF; Talalaev EP
[Ad] Address:Southern Federal University, Rostov-on-Don, 344006, Russian Federation; 89dmitry@mail.ru.
[Ti] Title:[Concentration of proinflammatory cytokines, peroxiredoxin-1 and glutathione peroxidase activity in the blood plasma of patients with coronary artery disease undergoing coronary artery bypass grafting].
[So] Source:Adv Gerontol;30(2):269-275, 2017.
[Is] ISSN:1561-9125
[Cp] Country of publication:Russia (Federation)
[La] Language:rus
[Ab] Abstract:76 patients with coronary heart disease (who had undergone coronary artery bypass grafting) were examined to investigate the role of pro-inflammatory cytokines and enzymes involved in redox regulation, in the mechanisms of development of systemic inflammatory response syndrome. Patients were divided into 2 groups: 1st - patients with coronary heart disease, who as a result of clinical trials has not been set postpericardiotomy syndrome; 2nd - patients with coronary heart disease who have been diagnosed postpericardiotomy syndrome. The blood plasma of both groups indicated intensification of production of interleukin-6, intrleukin-8, as well as - an imbalance in the peroxiredoxin-1 and glutathione peroxidase. These changes by patients with postpericardiotomy syndrome are observed at the earliest time and differed depth of expression. The results of this work confirm the high potential of the investigated indicators for prevention and monitoring postpericardiotomy syndrome development.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1706
[Cu] Class update date: 170602
[Lr] Last revision date:170602
[St] Status:In-Process

  7 / 394 MEDLINE  
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[PMID]: 28425090
[Au] Autor:van Osch D; Nathoe HM; Jacob KA; Doevendans PA; van Dijk D; Suyker WJ; Dieleman JM
[Ad] Address:Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.
[Ti] Title:Determinants of the postpericardiotomy syndrome: a systematic review.
[So] Source:Eur J Clin Invest;47(6):456-467, 2017 Jun.
[Is] ISSN:1365-2362
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Postpericardiotomy syndrome (PPS) is a common complication following cardiac surgery; however, the exact pathogenesis remains uncertain. Identifying risk factors of PPS might help to better understand the syndrome. The aim of this study was to provide an overview of existing literature around determinants of PPS in adult cardiac surgery patients. MATERIAL AND METHODS: Two independent investigators performed a systematic search in MEDLINE, EMBASE and the Cochrane Central Register. The search aimed to identify studies published between January 1950 and December 2015, in which determinants of PPS were reported. RESULTS: A total of 19 studies met the selection criteria. In these studies, 14 different definitions of PPS were used. The median incidence of PPS was 16%. After quality assessment, seven studies were considered eligible for this review. Lower preoperative interleukin-8 levels and higher postoperative complement conversion products were associated with a higher risk of PPS. Among other clinical factors, a lower age, transfusion of red blood cells and lower preoperative platelet and haemoglobin levels were associated with a higher risk of PPS. Colchicine use decreased the risk of PPS. CONCLUSION: We found that both the inflammatory response and perioperative bleeding and coagulation may play a role in the development of PPS, suggesting a multifactorial aetiology of the syndrome. Due to a lack of a uniform definition of PPS in the past, study comparability was poor across the studies.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1704
[Cu] Class update date: 170530
[Lr] Last revision date:170530
[St] Status:In-Process
[do] DOI:10.1111/eci.12764

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[PMID]: 28197356
[Au] Autor:Vasic N; Dimic-Janjic S; Stevic R; Milenkovic B; Djukanovic V
[Ad] Address:Clinic for Pulmonary Diseases, Clinical Center of Serbia, Belgrade, Serbia.
[Ti] Title:Acute "Pseudoischemic" ECG Abnormalities after Right Pneumonectomy.
[So] Source:Case Rep Surg;2017:7872535, 2017.
[Is] ISSN:2090-6900
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:New onset of electrocardiographic (ECG) abnormalities can occur after lung surgery due to the changes in the position of structures and organs in the chest cavity. The most common heart rhythm disorder is atrial fibrillation. So-called "pseudoischemic" ECG changes that mimic classic ECG signs of acute myocardial ischemia are also often noticed. We report the case of a 68-year-old male, with no prior cardiovascular disease, who underwent extensive surgical resection for lung cancer. On a second postoperative day, clinical and electrocardiographic signs of acute myocardial ischemia occurred. According to clinical course, diagnostic procedures, and therapeutic response, we excluded acute coronary syndrome. We concluded that physical lesion of the pericardium, caused by extended pneumonectomy with resection of the pericardium, provoked the symptoms and ECG signs that mimic acute coronary syndrome. Our final diagnosis was postpericardiotomy syndrome after extended pneumonectomy and further treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) was recommended. It is necessary to consider possibility that nature of ECG changes after extended pneumonectomy could be "pseudoischemic."
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1702
[Cu] Class update date: 170224
[Lr] Last revision date:170224
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1155/2017/7872535

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[PMID]: 28131509
[Au] Autor:Pulido JN
[Ad] Address:Cardiovascular Intensive Care Unit, Cardiothoracic Anesthesiology and Critical Care Medicine, Swedish Heart and Vascular Institute, Physicians Anesthesia Services, Seattle, Wash. Electronic address: juan.pulido@swedish.org.
[Ti] Title:The significance of postpericardiotomy syndrome: A real threat or a simple nuisance?
[So] Source:J Thorac Cardiovasc Surg;153(4):886-887, 2017 Apr.
[Is] ISSN:1097-685X
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:EDITORIAL
[Em] Entry month:1701
[Cu] Class update date: 170331
[Lr] Last revision date:170331
[St] Status:In-Data-Review

  10 / 394 MEDLINE  
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[PMID]: 27919456
[Au] Autor:van Osch D; Dieleman JM; Bunge JJ; van Dijk D; Doevendans PA; Suyker WJ; Nathoe HM; Dexamethasone for Cardiac Surgery Study Group
[Ad] Address:Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address: d.vanosch@umcutrecht.nl.
[Ti] Title:Risk factors and prognosis of postpericardiotomy syndrome in patients undergoing valve surgery.
[So] Source:J Thorac Cardiovasc Surg;153(4):878-885.e1, 2017 Apr.
[Is] ISSN:1097-685X
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVE: The study aim was to investigate the long-term prognosis and risk factors of postpericardiotomy syndrome (PPS). METHODS: We performed a single-center cohort study in 822 patients undergoing nonemergent valve surgery. Risk factors of PPS were evaluated using multivariable logistic regression analysis. We also compared the incidence of reoperation for tamponade at 1 year between patients with and without PPS. Main secondary outcomes were hospital stay and mortality. RESULTS: Of the 822 patients, 119 (14.5%) developed PPS. A higher body mass index (odds ratio (OR) per point increase, 0.94; 95% confidence interval (CI), 0.89-0.99) was associated with a lower risk of PPS, whereas preoperative treatment for pulmonary disease without corticosteroids (OR, 2.55; 95% CI, 1.25-5.20) was associated with a higher risk of PPS. The incidence of reoperation for tamponade at 1 year in PPS versus no PPS was 20.9% versus 2.5% (OR, 15.49; 95% CI, 7.14-33.58). One-year mortality in PPS versus no PPS was 4.2% versus 5.5% (OR, 0.68; 95% CI, 0.22-2.08). Median hospital stay was 13 days (interquartile range, 9-18 days) versus 11 days (interquartile range, 8-15 days) (P = .001), respectively. CONCLUSIONS: Despite longer hospital stays and more short-term reoperations for tamponade, patients with PPS had an excellent 1-year prognosis.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1612
[Cu] Class update date: 170331
[Lr] Last revision date:170331
[St] Status:In-Data-Review


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