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[PMID]: 25152283
[Au] Autor:Huang D; Ma X; Zhou D
[Ad] Address:Department of Anesthesiology, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou 310016, China.
[Ti] Title:[Effects of postoperative analgesia of ultrasound-guided transversus abdominis plane block in hemicolectomy patients].
[So] Source:Zhonghua Yi Xue Za Zhi;94(21):1623-6, 2014 Jun 3.
[Is] ISSN:0376-2491
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:OBJECTIVE: To investigate the effect of postoperative analgesia of ultrasound-guided transversus abdominis plane block in hemicolectomy patients. METHODS: After obtaining approval from the Hospital Ethics Committee and informed written consent from all patients, fourty hemicolectomy patients were randomly divided into two even groups. After anesthesia induction and intubation, patients recieved ultrasound-guided bilateral transversus abdominis plane block with 0.25% ropivacaine 60 ml (group A) or saline (group B). Post-operative patient-controlled intravenous analgesia with sufentanil was provided to all patients. RESULTS: Compared with group B, group A had less BP, HR changes at skin incision and needed less intraoperative sufentanil ((0.25 ± 0.16)µg/kg vs (0.35 ± 0.21)µg/kg) (P < 0.05) to maintain anesthesia. Group A had lower VAS than group B at 1, 4, 8, 12, 24 h after surgery (P < 0.05), less PCA demand (2.9 ± 1.6 vs 9.1 ± 1.8) (P < 0.05) and less PCA sufentanil consumption((69.1 ± 5.8)µg vs (92.6 ± 6.9)µg) (P < 0.05), thus less post-operative nausea or vomiting and higher satisfaction (P < 0.05). No complications associated to transversus abdominis plane block were found. CONCLUSION: Ultrasound-guided transversus abdominis plane block provided safe and effective post-operative analgesia for hemicolectomy patients.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1408
[Js] Journal subset:IM
[St] Status:In-Data-Review

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[PMID]: 25142636
[Au] Autor:Raposio E; Antonacci M; Caruana G
[Ad] Address:Department of Surgical Sciences, Plastic Surgeon Division, University of Parma, Via Gramsci 14, 43126 Parma, Italy. edoardo.raposio@unipr.it.
[Ti] Title:A simple technique for the excision of cutaneous carcinoma: the round block purse-string suture.
[So] Source:World J Surg Oncol;12:263, 2014.
[Is] ISSN:1477-7819
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Purse-string suture is a simple technique that can be used to reduce the surface area of circular wounds in an effort to obtain minimal scarring. In this report, we provide evidence of the effectiveness of the purse-string suture as a stand-alone procedure that allows a permanent primary complete closure of small to moderate skin defects. The procedure is used primarily for the repair of skin defects due to cutaneous tumor excision in older patients. METHODS: The purse-string suture is executed by using a 1-0 absorbable suture, always by exiting and reentering intradermally and never penetrating the epidermis, in a circumferential fashion. RESULTS: The immediate postoperative folds flatten in about a 4-week postoperative time span, and the resulting scar is the smallest obtainable. CONCLUSIONS: The round block purse-string suture is a simple technique which allows complete closure of skin defects without importing tissue from a distance, and it can be particularly suitable for older patients because of their skin laxity.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1408
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1186/1477-7819-12-263

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[PMID]: 25152805
[Au] Autor:Pefura-Yone EW; Kengne AP; Afane-Ze E; Kuaban C
[Ad] Address:Department of Internal Medicine and Subspecialties, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon ; Pneumology service, Yaounde Jamot Hospital, P.O Box: 4021, Yaounde, Cameroon....
[Ti] Title:Sensitisation to Blattella germanica among adults with asthma in Yaounde, Cameroon: a cross-sectional study.
[So] Source:World Allergy Organ J;7(1):22, 2014.
[Is] ISSN:1939-4551
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: German cockroach or Blattella germanica is commonly found in homes across the inter-tropical region. The contribution of sensitisation to Blattella germanica in people with asthma in sub-Saharan Africa has not received attention. The aim of this study was to assess the prevalence and investigate the predicting factors of sensitisation to Blattella germanica in patients with asthma in Yaounde, Cameroon. METHODS: This was a cross-sectional study conducted between January 2012 and June 2013. All patients (aged 15 years and above) with asthma, receiving care at the Yaounde Jamot Hospital and the CEDIMER medical practice during the study period and who had received a prick skin testing for perennial aeroallergens were included in the study. RESULTS: The final sample comprised 184 patients including 123 (66.8%) women. The median age (25th-75th percentiles) was 38 (24-54) years. Prick skin test for Blattella germanica was positive in 47 (25.5%) patients. Sensitisation to Blattella germanica was associated with a sensitisation to mite in 41 (87.2%) patients, a sensitisation to Alternaria in 18 (38.3%) patients, and a sensitisation to cat or dog dander in 7 (14.9%) patients. Independent predicting factors of a sensitisation to Blattella germanica were the sensitisation to Blomia tropicalis [adjusted odd ratio (95% confidence interval) 4.10 (1.67-10.04), p = 0.002] and sensitisation to Alternaria [3.67 (1.53-7.46), p = 0.003]. CONCLUSIONS: Sensitisation to Blattella germanica is present in about a quarter of adult patients with asthma in Yaounde. Sensitisation to Alternaria and Blomia tropicalis appears to be a powerful predicting factor of sensitisation to Blattella germanica in this setting.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1408
[Da] Date of entry for processing:140825
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1186/1939-4551-7-22

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[PMID]: 24916997
[Au] Autor:Aldwaikat M; Alarjah M
[Ad] Address:Faculty of Pharmacy, Umm Alqura University, Makkah, Saudi Arabia. Electronic address: maidwaik@yahoo.co.uk.
[Ti] Title:Investigating the sonophoresis effect on the permeation of diclofenac sodium using 3D skin equivalent.
[So] Source:Ultrason Sonochem;22:580-7, 2015 Jan.
[Is] ISSN:1873-2828
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:Ultrasound temporally increases skin permeability by altering stratum corneum SC function (sonophoresis). The objective of this study was to evaluate the effect of variable ultrasound conditions on the permeation of diclofenac sodium DS with range of physicochemical properties through EpiDermâ„¢. Permeation studies were carried out in vitro using Franz diffusion cell. HPLC method was used for the determination of the concentration of diclofenac sodium in receiving compartment. Parameters like ultrasound frequency, application time, amplitude, and mode of sonication and distance of ultrasound horn from skin were investigated, and the conditions where the maximum enhancement rate obtained were determined. Application of ultrasound enhanced permeation of diclofenac sodium across EpiDermâ„¢ by fivefolds. The most effective enhancing parameters were power sonication of 20kHz frequency, 20% amplitude at continuous mode for 5min.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1408
[Js] Journal subset:IM
[St] Status:In-Data-Review

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[PMID]: 25152810
[Au] Autor:Al-Badri MR; Azar ST
[Ad] Address:Department of Internal Medicine, Division of Endocrinology and Metabolism, American University of Beirut- Medical Center, New York, USA.
[Ti] Title:Effect of glucagon-like peptide-1 receptor agonists in patients with psoriasis.
[So] Source:Ther Adv Endocrinol Metab;5(2):34-8, 2014 Apr.
[Is] ISSN:2042-0188
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Glucagon-like peptide-1 (GLP-1) agonists are a class of drugs used for the treatment of type 2 diabetes mellitus. GLP-1 is released in response to meal intake; these classes of drugs enhance glucose-dependent insulin secretion and exhibit other antihyperglycemic effects following their release into the circulation from the gut. Psoriasis is a chronic skin condition affecting approximately 2% of the Western population. It is considered to be an autoimmune disease that involves the Th1 pathway and is associated with metabolic syndrome and its components, such as obesity, diabetes, and hypertension. We have reviewed reports in the literature that indicate a beneficial anti-inflammatory effect of GLP-1 in patients with diabetes or who have insulin resistance and psoriasis.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1408
[Da] Date of entry for processing:140825
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1177/2042018814543483

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[PMID]: 24231780
[Au] Autor:Lim JH; Wang SI; Kim DY; Song KJ; Kim TG; Lee KB
[Ad] Address:Department of Orthopaedic Surgery, Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Chonbuk National University Medical School, 634-18, Keum Am-dong, Dukjin-gu, Jeonju, 561-712, Korea....
[Ti] Title:Positional change of hyoid bone after anesthesia in anterior surgery of upper cervical spine.
[So] Source:Spine J;14(9):1890-4, 2014 Sep 1.
[Is] ISSN:1878-1632
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND CONTEXT: The hyoid bone is used as a landmark in anterior upper cervical spine operations and is supposed to represent the level of C3 body. However, this correspondence between hyoid bone position and cervical level is not static and changes during surgery (extension after anesthesia). PURPOSE: To find the cervical level corresponding to the position of hyoid bone before and after anesthesia and to evaluate the adequacy of its usage as a surgical landmark. STUDY DESIGN: A retrospective study. PATIENT SAMPLE: One hundred twenty-eight patients with degenerative cervical diseases who had undergone anterior cervical discectomy and fusion. OUTCOME MEASURE: Radiologic measure. METHODS: For each patient, preanesthesia neutral, preanesthesia extension, and postanesthesia induction extension C-spine lateral image were obtained. The level of cervical vertebra that midline of hyoid bone indicated was measured by radiological method. A cervical vertebra was divided into three segments, consisting of upper half, lower half, and disc space, and each of these segments was considered as one level. The differences between pre- and postanesthesia induction hyoid positions were classified as minimal change (one level or less) and significant change (two levels or greater). Relationship between positional change of hyoid bone to gender, obesity, and age were respectively investigated. RESULTS: There were 20 cases of one-level distal displacement of the hyoid bone, 40 cases of two-level distal displacement, 34 cases of three-level distal displacement, 16 cases of 4-level distal displacement, and two cases of five-level distal displacement. In eight cases, there was no level change, and in the remaining 8 cases, the hyoid bone had been displaced proximally. There were 34 cases of minimal change. The remaining 94 cases (73.4%) had significant changes. No respective relationship was found between sex, obesity, age and pre-and postanesthesia induction positional change of hyoid bone. CONCLUSIONS: Among the 128 cases studied, 73.4% hyoid bone positions had changed by more than one cervical vertebra body between the pre- to postanesthesia induction X-ray images. Sex, age, and body mass index were not associated with statistically significant differences in these positions. The hyoid bone should not be trusted as a landmark for upper cervical operations, and the cervical level to be operated should be confirmed by a radiological method before a skin incision is made.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1408
[Js] Journal subset:IM
[St] Status:In-Data-Review

  7 / 594168 MEDLINE  
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[PMID]: 25152815
[Au] Autor:Rdeini WM; Agbenorku P; Mitish VA
[Ad] Address:Seventh Day Adventist Hospital, Kumasi, Ghana.
[Ti] Title:Strategy of surgical management of peripheral neuropathy form of diabetic foot syndrome in ghana.
[So] Source:Plast Surg Int;2014:185023, 2014.
[Is] ISSN:2090-1461
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Introduction. Foot disorders such as ulceration, infection, and gangrene which are often due to diabetes mellitus are some major causes of morbidity and high amputation. Aim. This study aims to use a group of methods for the management of diabetic foot ulcers (DFU) in order to salvage the lower limb so as to reduce the rate of high amputations of the lower extremity. Materials and Methods. A group of different advanced methods for the management of DFU such as sharp debridement of ulcers, application of vacuum therapy, and other forms of reconstructive plastic surgical procedures were used. Data collection was done at 3 different hospitals where the treatments were given. Results. Fifty-four patients with type 2 diabetes mellitus were enrolled in the current study: females n = 37 (68.51%) and males n = 17 (31.49%) with different stages of PEDIS classification. They underwent different methods of surgical management: debridement, vacuum therapy (some constructed from locally used materials), and skin grafting giving good and fast results. Only 4 had below knee amputations. Conclusion. Using advanced surgical wound management including reconstructive plastic surgical procedures, it was possible to reduce the rate of high amputations of the lower limb.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1408
[Da] Date of entry for processing:140825
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1155/2014/185023

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[PMID]: 25152626
[Au] Autor:Fang S; Li S; Cai T
[Ad] Address:Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
[Ti] Title:Glucagonoma syndrome: a case report with focus on skin disorders.
[So] Source:Onco Targets Ther;7:1449-53, 2014.
[Is] ISSN:1178-6930
[Cp] Country of publication:New Zealand
[La] Language:eng
[Ab] Abstract:Glucagonoma syndrome is a rare paraneoplastic phenomenon. Necrolytic migratory erythema is often one of the first presenting symptoms. We report a case of a 55-year-old man with a 2-year history of recalcitrant eruption. Abdominal computer tomography was performed, which revealed a tumor in the tail of the pancreas. After pancreatectomy, his cutaneous lesions vanished in a few days. Skin symptoms are important, as they are often essential for early diagnosis of glucagonoma syndrome and may prevent metastatic disease; hence, in this report, we focus on skin disorders in glucagonoma syndrome.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1408
[Da] Date of entry for processing:140825
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.2147/OTT.S66285

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[PMID]: 24952130
[Au] Autor:Cunningham TJ; Crowell CR; Alger SE; Kensinger EA; Villano MA; Mattingly SM; Payne JD
[Ad] Address:University of Notre Dame, Department of Psychology, IN 46556, United States....
[Ti] Title:Psychophysiological arousal at encoding leads to reduced reactivity but enhanced emotional memory following sleep.
[So] Source:Neurobiol Learn Mem;114:155-64, 2014 Oct.
[Is] ISSN:1095-9564
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:While sleep's role in emotional memory processing is gaining increasing support, its effect on emotion regulation remains equivocal. Moreover, little is known about the link between emotional reactivity at the time of encoding and subsequent sleep-based emotional memory consolidation. This study examined whether sleep would potentiate, protect, or depotentiate measures of heart rate and skin conductance in response to scenes containing emotional and neutral objects, and assessed how these measures of reactivity would predict subsequent memory for the objects across delays of sleep and wake. Heart rate deceleration (HRD) and skin conductance response (SCR) data were collected at encoding and recognition. Although HRD and SCR reactivity to objects were depotentiated after a sleep-filled delay, they remained unchanged after a delay containing wakefulness. Moreover, increased arousal responses to negative scenes at encoding as measured by HRD and SCR responses were positively correlated with subsequent memory for the negative objects of scenes, but only in the sleep group. This suggests that larger reactions to negative images at the time of encoding set the stage for the preferential consolidation of these images during a night of sleep. Although arousal responses are often thought to account for emotional enhancement in long-term memory, these findings suggest that both an arousal response at encoding and a subsequent period of sleep are needed to optimize selective emotional memory consolidation.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1408
[Js] Journal subset:IM
[St] Status:In-Data-Review

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[PMID]: 25151006
[Au] Autor:Wohn CT; Pantelyushin S; Ober-Blöbaum JL; Clausen BE
[Ad] Address:Department of Immunology, Erasmus MC, University Medical Center Rotterdam, 3015 GE, Rotterdam, The Netherlands.
[Ti] Title:Aldara-induced psoriasis-like skin inflammation: isolation and characterization of cutaneous dendritic cells and innate lymphocytes.
[So] Source:Methods Mol Biol;1193:171-85, 2014.
[Is] ISSN:1940-6029
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Psoriasis is a chronic auto-inflammatory skin disease of unknown etiology affecting millions of people worldwide. Dissecting the cellular networks and molecular signals promoting the development of psoriasis critically depends on appropriate animal models. Topical application of Aldara cream containing the Toll-like receptor (TLR)7-ligand Imiquimod induces skin inflammation and pathology in mice closely resembling plaque-type psoriasis in humans. The particular power of the Aldara model lies in examining the early events during psoriatic plaque formation, which is difficult to achieve in patients. Hence, recent reports using this model have challenged currently prevailing concepts concerning the pathophysiology of psoriasis. Here, we describe the induction and phenotype of Aldara-mediated dermatitis in mice and, in particular, analysis of the inflammatory cell infiltrate using flow cytometry.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1408
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1007/978-1-4939-1212-4_16


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