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[PMID]: 25151908
[Au] Autor:Zhang J; Liu X; Liu Z; Li Y; Han Z; Xu J; Rong Y; Liu T; Zhang W; Jiang Y; Li X; Wang W; Wang H; Jia K; Liu W; Gao H; Zhang L
[Ad] Address:Laboratory of Circulatory Support, TEDA International Cardiovascular Hospital, Tianjin 300457, China. Email: zzjjmm126@126.com....
[Ti] Title:[In vivo evaluation of magnetic and hydrodynamic suspension centrifugal ventricular assist device].
[So] Source:Zhonghua Yi Xue Za Zhi;94(22):1740-3, 2014 Jun.
[Is] ISSN:0376-2491
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:OBJECTIVE: To verify the function of magnetic and hydrodynamic suspension centrifugal ventricular assist device in a sheep model. METHODS: The device was implanted into left ventricular apex on beating hearts. The outflow graft of each device was anastomosed to descending aorta in 11 animals. Hematologic, biochemical and blood clotting tests before and after surgery were performed. The data of pump functions were collected continuously. RESULTS: Among them, there were death from ventricular fibrillation (n = 3), acute pulmonary edema (n = 1) and left ventricular thrombus and molar cardiac muscle (n = 5). One animal survived for 75 days and died from bacterial infection after pumping for 59 hours. During assistance for 120 days, the flow rate was 3.0-3.4 L/min. All hematologic and biochemical parameters were within normal ranges in one sheep. The walking sheep wore the controller and lithium battery with a blood pump. Neither mechanical wearing nor thrombus formation was observed for inflow and outflow conduits or pump interior. CONCLUSIONS: The magnetic and hydrodynamic suspension centrifugal ventricular assist device demonstrates excellent hemocompatibility and reliability. And there is a great prospect of clinical success.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1408
[Js] Journal subset:IM
[St] Status:In-Data-Review

  2 / 1396859 MEDLINE  
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[PMID]: 25151904
[Au] Autor:Dong Y; Zhao M; Su M; Ding N; Zhang X
[Ad] Address:Department of Respiratory Medicine, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China....
[Ti] Title:[Efficacies of stimulation of genioglossus in mild-to-moderate obstructive sleep apnea syndrome patients after uvulopalatopharyngoplasty].
[So] Source:Zhonghua Yi Xue Za Zhi;94(22):1726-8, 2014 Jun.
[Is] ISSN:0376-2491
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:OBJECTIVE: To evaluate the efficacies of transcutaneous stimulation of genioglossus on remaining mild-to-moderate obstructive sleep apnea syndrome (OSAS) after uvulopalatopharyngoplasty (UPPP). METHODS: A total of 22 patients diagnosed with mild-to-moderate OSAS by polysomnography (PSG) after UPPP were recruited from Sleep Center of First Affiliated Hospital, Nanjing Medical University from February 2013 to October 2013 and underwent transcutaneous stimulation of genioglossus therapy at night. Prior to and during treatment overnight polysomnography examination was performed. Moreover, the sleepiness of patients was assessed according to the Epworth sleepiness scale (ESS) before and after treatment. Comparison was made to observe the effects of treatment on PSG parameters and daytime ESS. RESULTS: Compared with pre-treatment, nocturnal apnea hypopnea index (AHI) (9.3 ± 4.2 vs 18.3 ± 6.8), microarousal index (MAI) (6.5 ± 3.8 vs 11.2 ± 4.8), radio of duration pulse oxygen saturation (SpO2) < 90% to total sleep time (T90) ((5.1 ± 4.0)% vs (9.5 ± 4.0)%) and score of daytime ESS (8.8 ± 3.3 vs 9.4 ± 3.1) all significantly decreased (all P < 0.01) while mean SpO2 ((95.5 ± 1.0)% vs (94.4 ± 1.1)%) and minimal SpO2 ((88.6 ± 2.9)% vs (84.9 ± 4.6)%) were both significantly elevated (both P < 0.001). None of them experienced obvious discomforts during treatment. CONCLUSION: Submental transcutaneous electrical stimulation of genioglossus is an effective treatment for remaining mild-to-moderate OSAS after UPPP surgery.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1408
[Js] Journal subset:IM
[St] Status:In-Data-Review

  3 / 1396859 MEDLINE  
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[PMID]: 25151899
[Au] Autor:Xiao Y; Wu B; Qiu H; Xiong G; Lin G; Zhong G; Hu K; Pan W
[Ad] Address:Department of General Surgery, Chinese Academy of Medical Sciences & Peking Union Medical College Hospital, Beijing 100730, China. Email: xiaoy@pumch.cn....
[Ti] Title:[Effects of tumor distance from anal verge and types of operations on survival outcomes for low rectal cancer after neoadjuvant chemoradiotherapy].
[So] Source:Zhonghua Yi Xue Za Zhi;94(22):1705-9, 2014 Jun.
[Is] ISSN:0376-2491
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:OBJECTIVE: To assess the effects of neoadjuvant chemoradiotherapy on survival outcomes of low rectal cancer after sphincter-preserving or removing surgery. METHODS: A total of 135 patients with rectal cancer within 10 cm from anal verge after neoadjuvant chemoradiotherapy were enrolled into this retrospective study from 2005 to 2012 at a single institute. There were 79 males and 56 females with a mean age of (58 ± 12) years and an average distance of (5.2 ± 2.1) cm from anal verge. The effects of gender, age, distance of tumor from anal verge, surgical procedure, T-stage downstaging, lateral resection margin and post-treatment lymphatic node status on 3-year disease-free survival (DFS) were examined. RESULTS: The overall 3-year DFS was 85.2% (115/135). Among 95 sphincter-preserving operations, there were anterior resection (n = 79), anterior perineal plane for ultra low anterior resection (APPEAR) technique (n = 12), Hartmann procedure (n = 3) and Parks procedure (n = 1). Among 40 sphincter-removing operations, there were abdominoperineal resection (APR) procedure (n = 39) and intersphincteric resection(ISR) (n = 1). The survival of patients undergoing sphincter-preserving or removing procedures did not differ in 3-year DFS (85.3% (81/95) vs 85.0% (34/40) , χ(2) = 0.000, P = 0.985) . Lateral resection margin and post-treatment lymphatic node status significantly affected DFS. The differential level from anal verge showed a trend of close relationship to 3-year DFS (81.5% (22/27) for 2-3 cm, 82.5% (47/57) for 4-5 cm vs 95.1% (39/41) for 6-7 cm), but without statistic significance (χ(2) = 3.111, 3.522; P = 0.078, 0.061). The survival rate for patients with sphincter-preserving at 6-7 cm from anal verge was significantly higher than that at 4-5 cm (95.0% (38/40) vs 79.5% (31/39) ,χ(2) = 4.227, P = 0.039) , but showed no differences to that with sphincter-removing at 2-3 cm from anal verge (81.0% (17/21),χ(2) = 2.864, P = 0.091) . The multivariate analysis showed that post-treatment lymphatic node status was the only prognostic factor to 3-year DFS (Wald = 4.454, P = 0.035) . CONCLUSIONS: Lateral resection margin and post-treatment lymphatic node status play an important role on DFS for patients with low rectal cancer after neoadjuvant chemoradiotherapy. The distance from anal verge is correlated with 3-year disease-free survival. Patients with tumor at 4-5 cm from annal verge can not benefit for survival when they get sphincter-preserving operations.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1408
[Js] Journal subset:IM
[St] Status:In-Data-Review

  4 / 1396859 MEDLINE  
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[PMID]: 25152292
[Au] Autor:Sun C; Zhou Y; Chai W; Wang Y
[Ad] Address:Department of Orthopedics, Chinese PLA General Hospital, Beijing 100853, China....
[Ti] Title:[Analysis of microbiology and antibiotic susceptibility in 131 cases of prosthetic hip infections].
[So] Source:Zhonghua Yi Xue Za Zhi;94(21):1657-60, 2014 Jun 3.
[Is] ISSN:0376-2491
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:OBJECTIVE: To explore the microbiological etiology of prosthetic hip infections during two-staged revision and analyze antibiotic susceptibility of bacteria isolated from infected hip arthroplasty specimens so as to provide clinical recommendations for empiric prophylactic and therapeutic antibiotics therapy. METHODS: A retrospective review was conducted for hospitalized patients of prothetic hip infections during two-staged revision between January 1, 2007 and December 31, 2013. Suspicious intraoperative tissues were cultured and microbiological data sets and antibiotic susceptibility of bacteria were analyzed. RESULTS: A total of 131 patients met the inclusion criteria. Micro-organisms were isolated in 96 patients. The negative culture rate was 26.7%. Nearly half of primary diseases were of fractures and 31.29% of all infected patients had previous surgery. Gram-positive isolates were the most common genus encountered (n = 81, 74.3%), followed by Gram-negative isolates (n = 22, 20.2%) and fungal isolates (n = 6, 5.5%). Polymicrobial infections accounted for 11.5%. Coagulase-negative staphylococci was the most common causative organism of infection (n = 42, 38.5%), followed by Staphylococcus aureus (19.3%). The proportion of isolated methicillin-resistant Staphylococcus was 29.36% for all organisms and 44.4% for Staphylococcus. Gram-negative isolates were dominated by Pseudomonas aeruginosa and Escherichia coli. Fungal isolates were dominated by Candida albicans. Enterococcus was the most common causative organism of polymicrobialinfection. The results of antibiotic susceptibility showed cefazolin and cefuroxime were poorly susceptible to coagulase negative staphylococci (CNS) and methicillin-resistant staphylococcus (MRS). Some third and fourth-generation cephalosporins also had problems of bacterial resistance to Gram-negative isolates. Some antibiotics such as vancomycin, linezolid and rifampin were sensitive to Gram-positive isolates. Some antibiotics such as amikacin piperacillin/tazobactam, cefoperazone/sulbactam, levofloxacinareand carbapenems were sensitive to Gram-negative isolates. CONCLUSION: Most infections are caused by staphylococci. The proportion of isolated methicillin-resistant Staphylococcus is high. Empiric antibiotics should include vancomycin for Gram-positive organisms and piperacillin/tazobactam (cefoperazone/sulbactam), levofloxacinare or carbapenems for most Gram-negative bacteria. Antibiotics should be timely adjusted according to the antibiotic susceptibility results.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1408
[Js] Journal subset:IM
[St] Status:In-Data-Review

  5 / 1396859 MEDLINE  
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[PMID]: 25152290
[Au] Autor:Guo C; Ma C; Yu L
[Ad] Address:Department of Anesthesiology, Shantou Hospital Affiliated to Zhongshan University, Shantou 515031, China. Email: stzxyygcm@163.com.
[Ti] Title:[Comparative of coopdech bronchial blocker and double-lumen tube on one lung ventilation in children].
[So] Source:Zhonghua Yi Xue Za Zhi;94(21):1651-3, 2014 Jun 3.
[Is] ISSN:0376-2491
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:OBJECTIVE: To compare the application of Coopdech bronchial blocker and double lumen bronchial tube during one lung ventilation in children. METHODS: Forty children undergoing one lung ventilation for thoracic surgery at Shantou Central Hospital from January 2012 to June 2013, approved by hospital ethics committee, were randomized into Coopdech bronchial blocker group (group A) and double-lumen tube group (group B). Anesthetic management and lung isolation were performed according to a standardized protocol. Two groups of children with the intubation time, intubation success rate, collapse score, the frequency of postoperative hoarseness were recorded. Before and after one lung ventilation in patients of the two groups of PaCO2, PaO2 and airway pressure (PAW) changes were recorded. RESULTS: The intubation time in A was longer than those of group B ((224 ± 72)vs(165 ± 46) s, P < 0.05), the success rate of intubation(100% vs 85%, P < 0.05), collapse score in A group was higher than in group B (95% vs 75%, P < 0.05) , Sore throat hoarseness occurred after operation in A group was lower than in B group (10% vs 35%, P < 0.05) , PaO2 was higher in group A after one lung ventilation for 30 min ((206 ± 58)vs(148 ± 63) mmHg, P < 0.05), PaCO2 and PAW were lower than group B ((36 ± 4) vs (45 ± 7) mmHg;(21.6 ± 3.2)vs(29.3 ± 5.5) cm H2O, P < 0.05). CONCLUSION: The Coodech bronchial blocker provided effective surgical exposure with less throat injuries, higher intubation success rate, lower airway pressure in children during video-assisted thoracoscopic surgery.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1408
[Js] Journal subset:IM
[St] Status:In-Data-Review

  6 / 1396859 MEDLINE  
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[PMID]: 25152289
[Au] Autor:Xin Y; Guo Y; Jiang Y; Zhang H
[Ad] Address:Anesthesia and Operation Center, Chinese People's Liberation Army General Hospital, Beijing 100853, China....
[Ti] Title:[Effects of pri ming different low-dose rocurium on pharmacodynamics of mivacurium].
[So] Source:Zhonghua Yi Xue Za Zhi;94(21):1647-50, 2014 Jun 3.
[Is] ISSN:0376-2491
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:OBJECTIVE: To explore the effects of pri ming rocuronium on neuromuscular blockade produced by mivacurium. METHODS: Ethical approval was granted by the medical ethics committee of our hospital with a reference number of C-2013-018-01. A total of 120 ASA physical status I and II patients undergoing selective otorhinolaryngologic surgery under general anesthesia signed the form of informed consent. And they were randomly divided by a random number table into 4 groups. After a standardized imidazole-propofol-fentanyl induction, they received a saline placebo injection (GroupI) and a pri ming dose of rocuronium 0.06 mg/kg (GroupII) , rocuronium 0.075 mg/kg (Group III) and rocuronium 0.1 mg/kg (Group IV). An intubating dose of mivacurium 0.15 mg/kg was offered 3 minutes later. Anesthesia was maintained with propofol and remifentanyl continuous infusion. Neuromuscular block was monitored with train of four (TOF) stimulation. The onset time, reappearance of T1 (DUR TOFc 1), times of T1 25% and 75% recovery, recovery index and times of TOF25%, 75% and 90% recovery were recorded. RESULTS: The onset time of mivacurium was significantly shorter and the times of T1 25% and 75% recovery were significantly longer in groups of II, III and IV than those in groupI. No significant difference existed in recovery index among 4 groups. The onset time of mivacurium became progressively shorter with the growing pri ming dose of rocurium among three experiment groups. And it was not statistically significant. CONCLUSIONS: Pri ming rocuronium decreases the onset and intubating times of mivacurium without effect on recovery index. No significant difference exists in drug effect among 3 experiment groups.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1408
[Js] Journal subset:IM
[St] Status:In-Data-Review

  7 / 1396859 MEDLINE  
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[PMID]: 25152286
[Au] Autor:Wang H; Ao Y; Gong X; Chen L; Wang Y; Wang J; Yu J
[Ad] Address:Institute of Sports Medicine, Peking University Third Hospital, Beijing 100191, China....
[Ti] Title:[Predisposing factors of patellofemoral articular cartilage injury after anterior cruciate ligament reconstruction].
[So] Source:Zhonghua Yi Xue Za Zhi;94(21):1635-8, 2014 Jun 3.
[Is] ISSN:0376-2491
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:OBJECTIVE: To evaluate the effects of age, gender, tibial anterior laxity and time from surgery to follow-up on patellofemoral articular cartilage status after anterior cruciate ligament reconstruction by second-look arthroscopy. METHODS: A total of 102 patients undergoing arthroscopic anterior cruciate ligament reconstruction received second-look arthroscopy at least one year after operation. There were 71 males and 31 females with an average age of 27.1 (16-41) years. The average time from primary operation to second-look arthroscopy was 23 (12-51) months. Arthroscopic evaluations of patella and trochlea cartilage status for all patients were performed at initial anterior cruciate ligament reconstruction and second-look arthroscopy. The effects of age, gender, tibial anterior laxity and time from surgery to follow-up on patellofemoral articular cartilage status were retrospectively examined. RESULTS: Patellofemoral articular cartilage degeneration continued to aggravate after anterior cruciate ligament reconstruction. There was no significant gender difference in patella and trochlear cartilage status. The patellar cartilage of patients under 30 years was worse than that of patients aged 30 years and above. Even though there was no significant difference. However, no significant inter-group difference existed in trochlear cartilage damage. With regard to KT-2000 side-to-side differences (0-3 mm vs >3 mm), no significant difference existed in patella and trochlear cartilage status. No significant difference was also found in the status of patella and trochlear cartilage between patients with body mass index under 24 kg/m(2) and patients 24 kg/m(2) and higher. The patellar cartilage of patients within 24 months after operation was significantly worse than that of patients 24 months and longer. However it did not apply to trochlear cartilage. CONCLUSION: The degeneration of patellofemoral articular cartilage worsens after anterior cruciate ligament reconstruction. And significantly more severe lesions are found in patellar cartilage of patients within 24 months after operation.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1408
[Js] Journal subset:IM
[St] Status:In-Data-Review

  8 / 1396859 MEDLINE  
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[PMID]: 25152283
[Au] Autor:Huang D; Ma X; Zhou D
[Ad] Address:Department of Anesthesiology, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou 310016, China.
[Ti] Title:[Effects of postoperative analgesia of ultrasound-guided transversus abdominis plane block in hemicolectomy patients].
[So] Source:Zhonghua Yi Xue Za Zhi;94(21):1623-6, 2014 Jun 3.
[Is] ISSN:0376-2491
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:OBJECTIVE: To investigate the effect of postoperative analgesia of ultrasound-guided transversus abdominis plane block in hemicolectomy patients. METHODS: After obtaining approval from the Hospital Ethics Committee and informed written consent from all patients, fourty hemicolectomy patients were randomly divided into two even groups. After anesthesia induction and intubation, patients recieved ultrasound-guided bilateral transversus abdominis plane block with 0.25% ropivacaine 60 ml (group A) or saline (group B). Post-operative patient-controlled intravenous analgesia with sufentanil was provided to all patients. RESULTS: Compared with group B, group A had less BP, HR changes at skin incision and needed less intraoperative sufentanil ((0.25 ± 0.16)µg/kg vs (0.35 ± 0.21)µg/kg) (P < 0.05) to maintain anesthesia. Group A had lower VAS than group B at 1, 4, 8, 12, 24 h after surgery (P < 0.05), less PCA demand (2.9 ± 1.6 vs 9.1 ± 1.8) (P < 0.05) and less PCA sufentanil consumption((69.1 ± 5.8)µg vs (92.6 ± 6.9)µg) (P < 0.05), thus less post-operative nausea or vomiting and higher satisfaction (P < 0.05). No complications associated to transversus abdominis plane block were found. CONCLUSION: Ultrasound-guided transversus abdominis plane block provided safe and effective post-operative analgesia for hemicolectomy patients.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1408
[Js] Journal subset:IM
[St] Status:In-Data-Review

  9 / 1396859 MEDLINE  
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[PMID]: 25152855
[Au] Autor:Cianchi F; Macrì G; Indennitate G; Mallardi B; Trallori G; Biagini MR; Badii B; Staderini F; Perigli G
[Ad] Address:Department of Surgery and Translational Medicine, University of Florence, Florence, Italy ; Endocrine and Minimally Invasive Surgery, Azienda Ospedaliero-Universitaria Careggi, Center of Oncologic Minimally Invasive Surgery (COMIS), Department of Surgery and Translational Medicine, University of Flo...
[Ti] Title:Laparoscopic total gastrectomy using the transorally inserted anvil (OrVilâ„¢): a preliminary, single institution experience.
[So] Source:Springerplus;3:434, 2014.
[Is] ISSN:2193-1801
[Cp] Country of publication:Switzerland
[La] Language:eng
[Ab] Abstract:Laparoscopic total gastrectomy (LTG) is not a commonly performed procedure due to the difficulty associated with surgical reconstruction. We present our preliminary results after intracorporeal circular stapling esophagojejunostomy using the newly developed transorally inserted anvil (OrVilâ„¢, Covidien, MA, USA). Between 2008 and June 2013, 51 patients underwent laparoscopic gastrectomy with D2 lymph node dissection for gastric cancer. A total of 12 patients underwent LTG: of these, 5 received an intracorporeal linear side-to-side esophagojejunal anastomosis and the remaining 7 underwent intracorporeal circular stapling esophagojejunostomy using the OrVilâ„¢ system. Short-term outcomes were compared between the two groups. There were no intraoperative complications or conversions to open surgery in any patients. The mean operative time was significantly shorter in the OrVilâ„¢ than in the side-to-side group (261.4 ± 12.0 vs 333.0 ± 15.0 minutes, respectively, p = 0.005). Postoperative fluorography revealed no anastomosis leakage or stenosis in either groups. All patients resumed an oral liquid diet on postoperative day 5 and the mean postoperative hospital stay was 9 days. Intracorporeal circular stapling esophagojejunostomy using the OrVilâ„¢ system is technically feasible and safe in LTG. This technique may be considered a simple and time-saving alternative to the side-to-side linear esophagojejunostomy.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1408
[Da] Date of entry for processing:140825
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1186/2193-1801-3-434

  10 / 1396859 MEDLINE  
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[PMID]: 25152850
[Au] Autor:Virtanen KJ; Savolainen V; Tulikoura I; Remes V; Haapamäki V; Pajarinen J; Björkenheim JM; Paavola M
[Ad] Address:Department of Surgery, Helsinki University Central Hospital and University of Helsinki, Topeliuksenkatu 5, Helsinki, 00260 Finland....
[Ti] Title:Surgical treatment of chronic acromioclavicular joint dislocation with autogenous tendon grafts.
[So] Source:Springerplus;3:420, 2014.
[Is] ISSN:2193-1801
[Cp] Country of publication:Switzerland
[La] Language:eng
[Ab] Abstract:BACKGROUND: Conservative treatment of acromioclavicular (AC) joint dislocation is not always successful. A consequence of persistent AC joint dislocation may be chronic pain and discomfort in the shoulder region as well a sensation of constant AC joint instability and impaired shoulder function. Stabilization of the AC joint may reduce these sequels. MATERIALS AND METHODS: Due to chronic AC joint dislocation, 39 patients in our hospital underwent coracoclavicular (CC) ligament reconstruction with autogenous semitendinosus and gracilis tendons between May 2005 and April 2011. We examined 25 patients after a mean of 4.2 years. The outcomes were Constant shoulder Score (CS), Disabilities of the Arm, Shoulder and Hand (DASH), pain (Visual Analog Scale, VAS), cross-arm test, stability of the AC joint, and complications. The follow-up visits included anteroposterior and axillary radiographs. RESULTS: Mean CS was 83 in the injured shoulder and 91 in the uninjured shoulder (p = 0.002). Mean DASH was 14. In 14 patients, the AC joint was clinically stable; pain was minor. In radiographs, osteolysis of the lateral clavicle and tunnel widening were markedly common. Fracture of the coracoid process occurred in 5 patients, and 3 suffered a fracture of the clavicle; 2 had a postoperative infection. CONCLUSIONS: Anatomic reconstruction of CC ligaments showed a moderate subjective outcome at the 4-year follow-up. After surgery, almost half the AC joints failed to stabilize. Lateral clavicle osteolysis and tunnel widening were notably common complications.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1408
[Da] Date of entry for processing:140825
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1186/2193-1801-3-420


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