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[PMID]: 25024816
[Au] Autor:Anwar K; Desai M; Al-Bloushi N; Alam F; Cyprian FS
[Ad] Address:Khurshid Anwar, Clinical Science Department, College of Medicine, University of Sharjah, Emirates of Sharjah 27272, United Arab Emirates....
[Ti] Title:Prevalence and clinicopathological characteristics of appendiceal carcinoids in Sharjah (United Arab Emirates).
[So] Source:World J Gastrointest Oncol;6(7):253-6, 2014 Jul 15.
[Is] ISSN:1948-5204
[Cp] Country of publication:China
[La] Language:eng
[Ab] Abstract:AIM: To determine the incidence and clinico-pathological profile of appendiceal carcinoids in a cohort of patients undergoing emergency appendicectomies for clinically suspected acute appendicitis in Sharjah, United Arab Emirates (UAE). METHODS: The study included the retrospective data of 964 patients operated for clinically suspected acute appendicitis, and the resected specimens were received at Al-Qasmi Hospital (Sharjah) from January 2010 to December 2010. The data of the patients who were histologically reported to have carcinoid tumors of the appendix were extensively evaluated for the patient's demographics, indication for surgery, surgical procedure, tumor localization in the appendix, diameter of the lesion, concomitant appendicitis, immunohistochemistry studies and clinical follow-up. RESULTS: Out of the 964 patients included in the study, 9 (0.93%) were found to have appendiceal carcinoids. The mean age reported was 28.7 years with a male to female ratio of 2:1. Eight tumors were located near the tip of the appendix with a mean diameter of 3.3 mm, while the remaining one was near the proximal end of the appendix. All the cases were associated with concomitant suppurative appendicitis. In seven reported cases, tumors were confined to the muscular layer while in one case each there was an extension to the serosa and mesoappendix, respectively. All tumors were found to be positive for chromogranin A, synaptophysin and neuron-specific enolase on immunohistochemistry but negative for cytokeratin-7. None of the patients developed recurrence or any reportable complications in the short follow-up period (12-26 mo) that was arranged as a six-monthly re-evaluation by abdominal ultrasonography. CONCLUSION: Our study found a higher incidence of appendiceal carcinoids in patients undergoing emergency appendectomy for acute appendicitis in Sharjah, UAE compared to two previous studies from the Persian Gulf region. Interestingly, tumors were found to be more commonly in young males, which is in contrast to previous studies. Moreover, all the tumors were positive for common neuroendocrine markers.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1407
[Da] Date of entry for processing:140715
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.4251/wjgo.v6.i7.253

  2 / 1388206 MEDLINE  
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[PMID]: 25024627
[Au] Autor:Dugalic VD; Knezevic DM; Obradovic VN; Gojnic-Dugalic MG; Matic SV; Pavlovic-Markovic AR; Dugalic PD; Knezevic SM
[Ad] Address:Vladimir D Dugalic, Djordje M Knezevic, Slavko V Matic, Srbislav M Knezevic, Department of Hepatobiliary and Pancreatic Surgery, First Surgical University Hospital, Clinical Center of Serbia, School of Medicine, University of Belgrade, 11000 Belgrade, Serbia....
[Ti] Title:Drain amylase value as an early predictor of pancreatic fistula after cephalic duodenopancreatectomy.
[So] Source:World J Gastroenterol;20(26):8691-9, 2014 Jul 14.
[Is] ISSN:2219-2840
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:AIM: To determine predictors of clinically relevant pancreatic fistulas (CRPF) by measuring drain fluid amylase (DFA) in the early postoperative period. METHODS: This prospective clinical study included 382 patients with periampullary tumors that were surgically resected at our department between March 2005 and October 2012. A cephalic duodenopancreatectomy (DP) was performed on all patients. Two closed suction drains were placed at the end of the surgery. The highest postoperative DFA value was recorded and analyzed during the first three postoperative days and on subsequent days if the drains were kept longer. Pancreatic fistula (PF) was classified according to the International Study Group of Pancreatic Fistula (ISGPF) criteria. Postoperative complications were defined according to the Dindo-Clavien classification. All data were statistically analyzed. The optimal thresholds of DFA levels on the first, second and third postoperative days were estimated by constructing receiver operating curves, generated by calculating the sensitivities and specificities of the DFA levels. The DFA level limits were used to differentiate between the group without PF and the groups with biochemical pancreatic fistula (BPF) and CRPF. RESULTS: Pylorus-preserving duodenopancreatectomy was performed on 289 (75.6%) patients, while the remaining patients underwent a classic Whipple procedure (CW). The total incidence of PF was 37.7% (grade A 22.8%, grade B 11.0% and grade C 3.9%). Soft pancreatic texture (SPT) was present in 58.3% of patients who developed PF. Mortality was 4.2%. The median DFA value on the first postoperative day (DFA1) in patients who developed PF was 4520 U/L (range 350-99000 U/L) for grade A fistula (BPF) with a SPT and a diameter of the main pancreatic duct (MPD) of ≤ 3 mm. For grade B/C (CRPF), the median DFA1 value was 8501 U/L (range 377-92060 U/L) with a SPT and MPD of ≤ 3 mm. These values were significantly higher when compared to the patients who did not have PF (122; range 5-37875 U/L). The upper limit of DFA values for the first 3 postoperative days in the examined stages of PF were: DFA1 1200 U/L for the BPF and CRPF; DFA3 350 U/L for BPF and DFA3 800 U/L for CRPF. The determined values were highly significant and demonstrated a reliable diagnostic test for both BPF and CRPF. CONCLUSION: DFA1 ≥ 1200 U/L is an important predictive factor for PF of any degree. The trend of DFA3 (decrease of < 50%) compared to DFA1 is a significant factor in the differentiation of CRPF from transient BPF.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1407
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.3748/wjg.v20.i26.8691

  3 / 1388206 MEDLINE  
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[PMID]: 25024616
[Au] Autor:Tllez-vila FI; Villalobos-Garita A; Giovannini M; Chan C; Hernndez-Calleros J; Uscanga L; Ramrez-Luna M
[Ad] Address:Flix Ignacio Tllez-vila, Miguel ngel Ramrez-Luna, Endoscopy Department, Instituto Nacional de Ciencias Mdicas y Nutricin "Salvador Zubirn", Mexico City, CP 14000, Mxico....
[Ti] Title:Follow-up of patients with pseudotumoral chronic pancreatitis: Outcome and surveillance.
[So] Source:World J Gastroenterol;20(26):8612-6, 2014 Jul 14.
[Is] ISSN:2219-2840
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:AIM: To follow up patients with pseudotumoral chronic pancreatitis (PCP) to assess their outcome and identify an optimal surveillance interval. METHODS: Data obtained prospectively were analyzed in a retrospective manner. Patients with clinical evidence of chronic pancreatitis (abdominal pain in the epigastrium, steatorrhea, and diabetes mellitus), endoscopic ultrasound (EUS) criteria > 4, and EUS-fine needle aspiration (FNA) were included. A pseudotumor was defined as a non-neoplastic space-occupying lesion, a cause of chronic pancreatitis that may mimic changes typical of pancreatic cancer on CT or endoscopic ultrasound but without histological evidence. A real tumor was defined as a neoplastic space-occupying lesion because of pancreatic cancer confirmed by histology. RESULTS: Thirty-five patients with chronic pancreatitis were included, 26 (74.2%) of whom were men. Nine (25.7%) patients were diagnosed with pseudotumoral chronic pancreatitis and two (2/35; 5.7%) patients with pseudotumoral chronic pancreatitis were diagnosed with pancreatic cancer on follow-up. The time between the diagnosis of pseudotumoral chronic pancreatitis and pancreatic adenocarcinoma was 35 and 30 d in the two patients. Definitive diagnosis of pancreatic adenocarcinoma was made by surgery. In the remaining six patients with pseudotumoral chronic pancreatitis, the median of follow-up was 11 mo (range 1-22 mo) and they showed no evidence of malignancy on surveillance. In the follow-up of patients without pseudotumoral chronic pancreatitis but with chronic pancreatitis, none were diagnosed with pancreatic cancer. According to our data, older patients with chronic pancreatitis are at risk of pseudotumoral chronic pancreatitis. CONCLUSION: According to characteristics of patient, detection of PCP should lead a surveillance program for pancreatic cancer with EUS-FNA in < 1 mo or directly to surgical resection.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1407
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.3748/wjg.v20.i26.8612

  4 / 1388206 MEDLINE  
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[PMID]: 25024612
[Au] Autor:Sun ZQ; Han XN; Wang HJ; Tang Y; Zhao ZL; Qu YL; Xu RW; Liu YY; Yu XB
[Ad] Address:Zhen-Qiang Sun, Hai-Jiang Wang, Ze-Liang Zhao, Xian-Bo Yu, Department of Gastrointestinal Surgery, Affiliated Tumor Hospital, Xinjiang Medical University, Urumqi 830011, Xinjiang Uygur Autonomous Region, China....
[Ti] Title:Prognostic significance of preoperative fibrinogen in patients with colon cancer.
[So] Source:World J Gastroenterol;20(26):8583-91, 2014 Jul 14.
[Is] ISSN:2219-2840
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:AIM: To investigate the prognostic significance of preoperative fibrinogen levels in colon cancer patients. METHODS: A total of 255 colon cancer patients treated at the Affiliated Tumor Hospital of Xinjiang Medical University from June 1(st) 2005 to June 1(st) 2008 were enrolled in the study. All patients received radical surgery as their primary treatment method. Preoperative fibrinogen was detected by the Clauss method, and all patients were followed up after surgery. Preoperative fibrinogen measurements were correlated with a number of clinicopathological parameters using the Student t test and analysis of variance. Survival analyses were performed by the Kaplan-Meier method and Cox regression modeling to measure 5-year disease-free survival (DFS) and overall survival (OS). RESULTS: The mean preoperative fibrinogen concentration of all colon cancer patients was 3.17 0.88 g/L. Statistically significant differences were found between preoperative fibrinogen levels and the clinicopathological parameters of age, smoking status, tumor size, tumor location, tumor-node-metastasis (TNM) stage, modified Glasgow prognostic scores (mGPS), white blood cell (WBC) count, neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and carcinoembryonic antigen (CEA) levels. Univariate survival analysis showed that TNM stage, tumor cell differentiation grade, vascular invasion, mGPS score, preoperative fibrinogen, WBC, NLR, PLR and CEA all correlated with both OS and DFS. Alpha-fetoprotein (AFP) and body mass index correlated only with OS. Kaplan-Meier analysis revealed that both OS and DFS of the total cohort, as well as of the stage II and III patients, were higher in the hypofibrinogen group compared to the hyperfibrinogen group (all P < 0.05). In contrast, there was no significant difference between OS and DFS in stage I patients with low or high fibrinogen levels. Cox regression analysis indicated preoperative fibrinogen levels, TNM stage, mGPS score, CEA, and AFP levels correlated with both OS and DFS. CONCLUSION: Preoperative fibrinogen levels can serve as an independent prognostic marker to evaluate patient response to colon cancer treatment.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1407
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.3748/wjg.v20.i26.8583

  5 / 1388206 MEDLINE  
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[PMID]: 23984711
[Au] Autor:Szwed K; Pawliszak W; Anisimowicz L; Bucinski A; Borkowska A
[Ad] Address:Department of Clinical Neuropsychology, Nicolaus Copernicus University, Collegium Medicum , Bydgoszcz , Poland.
[Ti] Title:Short-term outcome of attention and executive functions from aorta no-touch and traditional off-pump coronary artery bypass surgery.
[So] Source:World J Biol Psychiatry;15(5):397-403, 2014 Jul.
[Is] ISSN:1814-1412
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Abstract Objectives. Postoperative cognitive dysfunction (POCD) is an important neuropsychiatric complication of coronary artery bypass grafting (CABG). It is most likely caused by microembolic brain damage and affects domains of attention, memory, executive functions and dexterity. In order to achieve better neuroprotection, surgeons introduced some advantageous operating procedures. Noteworthy among them is a state-of-the-art off-pump CABG aorta no-touch technique ("no touch" OPCABG). The aim of this study was to investigate the short-term effect of "no touch" OPCABG on patients' attention and executive functions. Methods. In this prospective, observational, single-surgeon trial, 74 patients scheduled for elective CABG were studied. Thirty-five patients underwent "no-touch" OPCABG and were compared to 39 patients who underwent "traditional" OPCABG. Subjects underwent neurological and neuropsychological evaluation at the time of admission (7 2 days preoperatively) and discharge (7 days postoperatively). Results. Patients who underwent "traditional" OPCABG showed a significant decline in postoperative performance on 4 neuropsychological tests, while patients treated with "no touch" OPCABG showed a significant decline on 1 test. Twenty patients from "traditional" OPCABG group and ten patients from "no touch" OPCABG group were diagnosed with POCD. Conclusions. Use of "no touch" OPCABG was associated with better attention and executive functions 1 week after surgery compared with "traditional" OPCABG.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1407
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.3109/15622975.2013.824611

  6 / 1388206 MEDLINE  
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[PMID]: 25023238
[Au] Autor:Hampel C; Roos F; Neisius A; Throff JW; Thomas C
[Ad] Address:Urologische Klinik und Poliklinik, Universittsmedizin der Johannes-Gutenberg-Universitt Mainz, Langenbeckstrae 1, 55131, Mainz, Deutschland, jasmin.wrogemann@unimedizin-mainz.de.
[Ti] Title:Komplikationsmanagement bei der Deszensus- und Inkontinenzchirurgie. [Complication management in prolapse and incontinence surgery].
[So] Source:Urologe A;53(7):1017-29, 2014 Jul.
[Is] ISSN:1433-0563
[Cp] Country of publication:Germany
[La] Language:ger
[Ab] Abstract:Tension-free alloplastic slings (TFAS) have revolutionized surgery for female stress urinary incontinence for more than 20years. The procedure is easy to perform, minimally invasive with a short operating time in an outpatient setting and has proven efficacy comparable to retropubic colposuspension. The frequency of surgery for female stress incontinence has tripled within one decade which has to have an impact on the number of complications. In contrast, sacrocolpopexy has remained the gold standard in urological prolapse surgery as none of the new techniques has reached similar efficacy or safety; however, possible complications have to be named and their causes have to be understood to maintain the highest quality of care in the future. Possible complications of TFAS are potentially underestimated with respect to prevalence and manageability. Possible complications of prolapse and incontinence surgery are presented and the underlying causes are identified. Knowledge of the pathophysiology and the cause of complications together with the results of a postoperative diagnostic work-up, allow complication management to be tailored to each individual patient. To prevent complications all conservative treatment options should have been tried preoperatively and a complete evaluation (including urodynamics) should have been carried out for every patient. Postoperative urodynamics may help to document treatment success and to identify and quantify complications.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1407
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1007/s00120-014-3496-2

  7 / 1388206 MEDLINE  
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[PMID]: 25023234
[Au] Autor:Saar M; Ohlmann CH; Janssen M; Stckle M; Siemer S
[Ad] Address:Klink fr Urologie und Kinderurologie, Universittsklinikum des Saarlandes, Kirrberger Strae 1, Geb. 6, 66421, Homburg/Saar, Deutschland, Matthias.Saar@uks.eu.
[Ti] Title:Die radikale Prostatektomie : Intra- und postoperative Komplikationen erkennen und behandeln. [Radical prostatectomy : Detection and management of intra- and postoperative complications].
[So] Source:Urologe A;53(7):976-83, 2014 Jul.
[Is] ISSN:1433-0563
[Cp] Country of publication:Germany
[La] Language:ger
[Ab] Abstract:Radical prostatectomy is the most common treatment for organ-confined prostate cancer. Performed without complications and limitations, surgery will allow complete removal of the tumor and, therefore, cure the patient. Operative techniques have been improved during the last few decades to reduce invasiveness of the procedure. Furthermore, optimized perioperative management has shortened hospital stay. To ensure rapid recovery of each patient, early detection of complications is highly relevant. Herein, different scenarios for peri- and postoperative complications are described, and recommendations for best practice solutions are reviewed.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1407
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1007/s00120-014-3500-x

  8 / 1388206 MEDLINE  
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[PMID]: 24927779
[Au] Autor:Kocot A; Riedmiller H
[Ad] Address:Klinik und Poliklinik fr Urologie und Kinderurologie, Julius-Maximilians-Universitt, Oberdrrbacher Str. 6, 97080, Wrzburg, Deutschland, kocot_a@klinik.uni-wuerzburg.de.
[Ti] Title:Management und Prvention von Komplikationen bei offener Harnrhrenchirurgie : End-zu-End-Anastomose und Mundschleimhauturethroplastik. [Management and prevention of complications in open urethral surgery : End-to-end anastomosis and buccal mucosa urethroplasty].
[So] Source:Urologe A;53(7):1006-10, 2014 Jul.
[Is] ISSN:1433-0563
[Cp] Country of publication:Germany
[La] Language:ger
[Ab] Abstract:Open operative procedures for urethral reconstruction (i.e. stricture resection with primary end-to-end anastomosis and buccal mucosa urethroplasty) are established and proven techniques with a low complication profile and high success rates. The aim of this operative technique is removal of the urethral obstruction to avoid far-reaching complications for the whole urinary tract. Despite excellent long-term results, complications are not completely avoidable in both techniques. A successful complication management requires the complete spectrum of reconstructive techniques in addition to appropriate operative expertise in order to be able to achieve the optimal result even in cases of complications. Simultaneously the recognition of potential risks contributes to a further reduction of early and delayed complications both in the approach to the operative intervention as well as intraoperatively.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1407
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1007/s00120-014-3513-5

  9 / 1388206 MEDLINE  
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[PMID]: 24705476
[Au] Autor:Weckermann D
[Ad] Address:Urologische Klinik, Klinikum Augsburg, Stenglinstrae 2, 86156, Augsburg, Deutschland, dorothea.weckermann@klinikum-augsburg.de.
[Ti] Title:Pelvine Lymphadenektomie : Komplikationsmanagement. [Pelvic lymph node dissection : Complication management].
[So] Source:Urologe A;53(7):996-1000, 2014 Jul.
[Is] ISSN:1433-0563
[Cp] Country of publication:Germany
[La] Language:ger
[Ab] Abstract:Extended pelvic lymph node dissection allows exact lymph node staging and has the potential to improve prognosis. In addition to these advantages, there are some perioperative and postoperative complications. In case of transection of the obturator nerve, a microsurgical end-to-end anastomosis should be performed.The most frequent postoperative complication is (symptomatic) lymphocele which is predominantly diagnosed after extraperitoneal surgery. Meticulous lymph node dissection with clipping of lymphatic vessels, sparing the lateral wall of the external iliac artery from dissection, sufficient postoperative drainage, and application of low molecular weight heparin in the upper arm may reduce their incidence.Instillation of sclerosing agents and sufficient drainage are normally successful. If not, laparoscopic fenestration of lymphocele should be performed. Regular ultrasound examinations are necessary to diagnose and treat postoperative lymphocele in a timely manner.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1407
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1007/s00120-014-3480-x

  10 / 1388206 MEDLINE  
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[PMID]: 25024725
[Au] Autor:Kim JH; Kim SS; Ha KS; Bae J; Park Y
[Ad] Address:Division of Pulmonology, Department of Internal Medicine, Cheongju St. Mary's Hospital, The Catholic University of Korea College of Medicine, Cheongju, Korea....
[Ti] Title:Anomalous arterial supply to normal Basal segment of the right lower lobe: endovascular treatment with the amplatzer vascular plug.
[So] Source:Tuberc Respir Dis (Seoul);76(6):295-8, 2014 Jun.
[Is] ISSN:1738-3536
[Cp] Country of publication:Korea (South)
[La] Language:eng
[Ab] Abstract:Pulmonary systemic arterialization to normal basal lung without sequestration is a rare congenital anomaly. In this rare abnormality, arterialization of the left lower lobe is the most common type. In general, surgical treatments have been performed. Recently, for reducing the complications and risks of surgery, embolization is mainly attempted by using coils. We report a case of 22-year-old male patient with a 10 mm anomalous arterial supply to his normal lung, which is being successfully treated by transcatheter embolization when using the Amplatzer Vascular Plug that has been adapted for the treatment of high-flows and large artery occlusions.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1407
[Da] Date of entry for processing:140715
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.4046/trd.2014.76.6.295


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