Database : MEDLINE
Search on : thyroid and hormones [Words]
References found : 39534 [refine]
Displaying: 1 .. 10   in format [Detailed]

page 1 of 3954 go to page                         

  1 / 39534 MEDLINE  
              next record last record
select
to print
Photocopy
Full text

[PMID]: 29524524
[Au] Autor:Suzuki M; Banno K; Usui T; Funasaka N; Segawa T; Kirihata T; Kamisako H; Ueda K; Munakata A
[Ad] Address:Nihon University, Kameino, Kanagawa, Japan. Electronic address: suzuki.miwa@nihon-u.ac.jp.
[Ti] Title:Seasonal changes in plasma levels of thyroid hormones and the effects of the hormones on cellular ATP content in common bottlenose dolphin.
[So] Source:Gen Comp Endocrinol;, 2018 Mar 07.
[Is] ISSN:1095-6840
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:In general, thyroid hormones (THs) stimulate cellular metabolism by inducing ATP utilization that collaterally leads to thermogenesis. However, in cetaceans, TH functions and the contribution of THs to cold adaptation are not fully understood. To investigate the role of THs in metabolism of cetaceans, seasonal changes in circulating levels in thyroxine (T ) were investigated in the common bottlenose dolphin Tursiops truncatus that were monitored under two different conditions for two years, with routine measurements of body temperature (BT), water temperature (WT) and air temperature (AT). The effects of THs on ATP synthesis were determined using cultured cells. Blood samples were collected from the species kept in different conditions at the Taiji Whale Museum located in the temperate zone and at Okinawa Expo Park in the subtropical zone. Circulating levels in total T for the dolphins at both aquaria and total T levels in dolphins at Taiji were measured by enzyme-linked immunoassay methods, and average concentrations were compared among seasons. To confirm the effects of THs on ATP synthesis, T or T was administrated to cultured kidney cells from the same species and cellular ATP contents were quantified at 0, 24, 48, 96 and 192 hours after administration. BT of common bottlenose dolphins in each aquarium was measured for health check every morning. WT in pools and AT were also measured every morning. Circulating T levels in autumn and winter were lower than those in spring and summer in dolphins in Taiji where WT and AT varied greatly from season to season. T levels showed a small difference between spring and autumn in dolphins in Okinawa with warmer WT and AT in smaller amplitude ranges than in Taiji. Total T level in Taiji was highest in spring and lowest in autumn as T levels, but not significant. The BT of dolphins in Taiji was also lower in autumn and winter compared with those in spring and summer, whereas the BT of dolphins in Okinawa fell in autumn but rose in summer, albeit to a lesser extent than in Taiji. Cellular ATP was increased by administration of both T and T compared to control. Collectively, these results suggest that the cellular metabolic activities regulated by THs may be enhanced in dolphins exposed to increasing surrounding temperature for lypolysis and reduced in dolphins exposed to colder conditions for fat accumulation.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180310
[Lr] Last revision date:180310
[St] Status:Publisher

  2 / 39534 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29523010
[Au] Autor:Abdi H; Gharibzadeh S; Tasdighi E; Amouzegar A; Mehran L; Tohidi M; Azizi F
[Ad] Address:Endocrine Research Center, Research Institute for Endocrine Sciences, Tehran, Iran.
[Ti] Title:Associations Between Thyroid and Blood Pressure in Euthyroid Adults: A 9-Year Longitudinal Study.
[So] Source:Horm Metab Res;50(3):236-241, 2018 Mar.
[Is] ISSN:1439-4286
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:Longitudinal studies considering associations between thyroid function in the reference range (RR) with blood pressure (BP) are scarce and contradictory. We aimed to investigate the associations of serum thyrotropin (TSH) and free T4 (FT4) with different components of BP also incident prehyperetension (preHTN) and HTN during a 9-year follow-up. A sum of 2282 euthyroid individuals from an ongoing population-based cohort study were selected. A sex-stratified multivariate generalized estimating equation (GEE) method was employed. Moreover, a multivariate transitional model was used considering preceding BP status as a predictor of dichotomous outcomes of preHTN and HTN. Multivariate-adjusted GEE analysis revealed a decreasing trend for systolic BP (SBP), diastolic BP (DBP), mean arterial pressure (MAP) and pulse pressure (PP) throughout the study period in both men and women, either adjusted for serum TSH or FT4 levels. Serum FT4 within the RR was positively associated with all BP parameters in total population and in men, but serum TSH had a statistically significant mild increasing effect only on SBP, DBP and MAP of men. Multivariate transitional model found no association between serum TSH levels within the reference range (RR) and BP status; regarding serum FT4, a 1 ng/dl higher FT4 was associated with 40% increased risk of preHTN [OR (95% CI), 1.40 (1.02-1.90)], but not with HTN [OR (95% CI), 0.93 (0.80-1.09)]. It is concluded that serum FT4 within the RR is more strongly associated with BP parameters compared to TSH. This association is not consistent between men and women. Moreover, higher FT4 is associated with increased risk of preHTN.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:In-Process
[do] DOI:10.1055/s-0044-101756

  3 / 39534 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29522555
[Au] Autor:Bolotovskiy AA; Levina MA; DeFaveri J; Merilä J; Levin BA
[Ad] Address:Papanin Institute for Biology of Inland Waters, Russian Academy of Sciences, Borok, Yaroslavl Prov., Russia.
[Ti] Title:Heterochronic development of lateral plates in the three-spined stickleback induced by thyroid hormone level alterations.
[So] Source:PLoS One;13(3):e0194040, 2018.
[Is] ISSN:1932-6203
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:The three-spined stickleback Gasterosteus aculeatus is an important model for studying microevolution and parallel adaptation to freshwater environments. Marine and freshwater forms differ markedly in their phenotype, especially in the number of lateral plates, which are serially repeated elements of the exoskeleton. In fishes, thyroid hormones are involved in adaptation to salinity, as well as the developmental regulation of serially repeated elements. To study how thyroid hormones influence lateral plate development, we manipulated levels of triiodothyronine and thiourea during early ontogeny in a marine and freshwater population with complete and low plate phenotypes, respectively. The development of lateral plates along the body and keel was heterochronic among experimental groups. Fish with a low dosage of exogenous triiodothyronine and those treated with thiourea exhibited retarded development of bony plates compared to both control fish and those treated with higher a triiodothyronine dosage. Several triiodothyronine-treated individuals of the marine form expressed the partial lateral plate phenotype. Some individuals with delayed development of lateral plates manifested 1-2 extra bony plates located above the main row of lateral plates.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:In-Data-Review
[do] DOI:10.1371/journal.pone.0194040

  4 / 39534 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy

[PMID]: 29431947
[Au] Autor:Lapko IV; Kiryakov VA; Pavlovskaya NA; Oshkoderov OA; Klimkina KV
[Ti] Title:[Choice of informative laboratory biomarkers for the early identification of changes in neurohumoral regulation and carbohydrate exchange in workers of the mining and mechanical engineering industry].
[So] Source:Gig Sanit;95(11):1061-5, 2016.
[Is] ISSN:0016-9900
[Cp] Country of publication:Russia (Federation)
[La] Language:rus
[Ab] Abstract:The diagnostic significance of hormones and integral indices of pituitary-adrenal, pituitary-thyroid and pituitary-gonadal system and carbohydrate metabolism (ACTH (corticotropin), aldosterone, cortisol, TSH (thyroid-stimulating hormone), free triiodothyronine (fT3), free thyroxine (fT4), luteinizing hormone (LH), follicle-stimulating hormone (FSH), total and free testosterone, insulin, integral pituitary-adrenal index (IPAI), the pituitary-thyroid index (PTI), indices of carbohydrate metabolism (Caro and HOMA-IR) was studied for the early diagnostics of disorders of neurohumoral regulation in workers of mining and mechanical engineering industries. The most informative indices, permitting to identify disorders of carbohydrate metabolism are established to be indices of insulin resistance (index Caro and index NOMA-IR) and the determination of insulin in serum. For the identification of changes in pituitary adrenal, pituitary-thyroid and pituitary-gonadal system in patients with vibration disease, sensory-neural hearing loss, comorbidity indexes IGNI, ITI, concentrations of LH and total testosterone are of the most diagnostically significance.
[Mh] MeSH terms primary: Adrenocorticotropic Hormone/blood
Follicle Stimulating Hormone/blood
Insulin/blood
Occupational Diseases
Thyrotropin/blood
[Mh] MeSH terms secundary: Adult
Biomarkers/blood
Carbohydrate Metabolism/physiology
Extraction and Processing Industry/methods
Extraction and Processing Industry/standards
Female
Humans
Hypothalamo-Hypophyseal System/metabolism
Male
Middle Aged
Occupational Diseases/blood
Occupational Diseases/diagnosis
Occupational Diseases/etiology
Occupational Diseases/prevention & control
Occupational Health
Pituitary-Adrenal System/metabolism
Reproducibility of Results
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Biomarkers); 0 (Insulin); 9002-60-2 (Adrenocorticotropic Hormone); 9002-68-0 (Follicle Stimulating Hormone); 9002-71-5 (Thyrotropin)
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[Js] Journal subset:IM
[Da] Date of entry for processing:180213
[St] Status:MEDLINE

  5 / 39534 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29521578
[Au] Autor:Bastos MAV; Bastos PRHO; Osório IHS; Pinheiro SAM; Iandoli D; Lucchetti G
[Ad] Address:Federal University of Mato Grosso do Sul.
[Ti] Title:Physiologic correlates of culture-bound dissociation: A comparative study of Brazilian spiritist mediums and controls.
[So] Source:Transcult Psychiatry;:1363461518759202, 2018 Jan 01.
[Is] ISSN:1461-7471
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Mediumship and spirit possession are cultural phenomena found in many societies worldwide. In Brazil, Spiritism (a tradition in which mediumship is emphasized) is the third largest religious denomination. The present study aimed to investigate physiologic correlates of nonpathological dissociative experiences by comparing 20 female spiritist mediums with several years of socially sanctioned practice to 20 female nonmedium control subjects from the same religious context. We measured plasma levels of hormones and neuroactive substances, as well as vital signs and heart rate variability (HRV) parameters, before and immediately after spirit communication. Although no between-group differences were noted in basal physiological parameters, in response to the possession experiences the groups differed in heart rate and in plasma concentrations of noradrenaline, thyroid-stimulating hormone (TSH), prolactin, and creatine phosphokinase (CPK). The changes in parameters indicated an arousal response in mediums and a relaxation response in control participants, and the same pattern of changes was observed in HRV parameters from each group during the possession experiences. However, the changes in physiologic parameters for mediums were mild and of short duration: 1 hour after the possession experiences, no difference in cardiac autonomic regulation was noted. No significant group effect was noted for melatonin. Cognitive control processes may explain the arousal associated with the dissociative state. Findings from this study suggest that pathological and nonpathological dissociation may have different physiological correlates.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1177/1363461518759202

  6 / 39534 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29519736
[Au] Autor:Rajabi M; Yalcin M; Mousa SA
[Ad] Address:The Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, Rensselaer, NY, USA.
[Ti] Title:Synthesis of new analogs of tetraiodothyroacetic acid (tetrac) as novel angiogenesis inhibitors for treatment of cancer.
[So] Source:Bioorg Med Chem Lett;, 2018 Feb 26.
[Is] ISSN:1464-3405
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:In the angiogenesis process, integrins, which are members of a family of cell surface transmembrane receptors, play a critical role particularly in blood vessel formation and the local release of vascular growth factors. Thyroid hormones such as l-thyroxine (T ) and 3,5,3'-triiodo-l-thyronine (T ) promote angiogenesis and tumor cell proliferation via integrin αvß3 receptor. At or near an arginine-glycine-aspartate (RGD) recognition site on the binding pocket of integrin α ß , tetraiodothyroacetic acid (tetrac, a deaminated derivative of T ) is a thyrointegrin receptor antagonist and blocks the actions of T and T as well as different growth factors-mediated angiogenesis. In this study, we synthesized novel tetrac analogs by modifying the phenolic moiety of tetrac and tested them for their anti-angiogenesis activity using a Matrigel plug model for angiogenesis in mice. Pharmacological activity results showed that tetrac can accommodate numerous modifications and maintain its anti-angiogenesis activity.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher

  7 / 39534 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29518865
[Au] Autor:Zhang JP; Guo QH; Mu YM; Lyu ZH; Gu WJ; Yang GQ; Du J; Ba JM; Lu JM
[Ad] Address:Department of Endocrinology, Chinese PLA General Hospital, Beijing 100853, China.
[Ti] Title:[Clinical characteristics of central diabetes insipidus: a retrospective analysis of 230 cases].
[So] Source:Zhonghua Nei Ke Za Zhi;57(3):201-205, 2018 Mar 01.
[Is] ISSN:0578-1426
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:To evaluate the clinical characteristics and etiologies of central diabetes insipidus (CDI). The clinical data of 230 patients with CDI in the Department of Endocrinology of Chinese PLA General Hospital from 2008 June to 2014 December were collected and analyzed retrospectively. The three most common causes of CDI were idiopathic CDI, lymphocytic hypophysitis and intracranial germ cell tumors. Among all the CDI, the idiopathic CDI accounted for 37.48%. There were significant differences in age onset and gender distribution among the different causes of CDI. The patients with intracranial germ cell tumors [age of onset(19.2±10.2) years] were younger than the other types of CDI. Germ cell tumors patients were more common in male, and lymphocytic hypophysitis patients were more common in female. The most frequent abnormality of anterior pituitary in patients with CDI was growth hormone deficiency, followed by hypogonadism, adrenal insufficiency and hypothyroidism. The dysfunction of thyroid axis and adrenal axis in patients with germ cell tumor was more common than those in patients with idiopathic and lymphocytic hypophysitis. The most common causes of central diabetes insipidus were idiopathic CDI, lymphocytic hypophysitis and intracranial germ cell tumors. There were differences in age of onset, gender distribution and abnormal production of anterior pituitary hormones among all causes of CDI patients.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:In-Process
[do] DOI:10.3760/cma.j.issn.0578-1426.2018.03.010

  8 / 39534 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29518763
[Au] Autor:Angelousi A; Settas N; Faucz FR; Lyssikatos C; Quezado M; Nasiri-Ansari N; Stratakis CA; Kassi E
[Ad] Address:1st Department of Internal Medicine, Laiko Hospital, Medical School, National and Kapodistrian University of Athens, Greece, Section on Endocrinology & Genetics, Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD), National Insitutes of Health (NIH), Bethesd
[Ti] Title:Medullary thyroid cancer, leukemia, mesothelioma and meningioma associated with germline APC and RASAL1 variants: a new syndrome?
[So] Source:Hormones (Athens);16(4):423-428, 2017 Oct.
[Is] ISSN:1109-3099
[Cp] Country of publication:Greece
[La] Language:eng
[Ab] Abstract:Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor hereditary in 35% of cases. The most common syndromic form is in the context of the multiple endocrine neoplasia type 2 (MEN 2) syndromes in association with other tumors and due to germline RET mutations. We describe a 57-year-old female patient diagnosed with sporadic MTC. The patient had a history of other neoplasias, such as acute myeloid leukemia, for which she had received chemotherapy, and two other solid tumors, peritoneal mesothelioma and meningioma. Genetic analyses were carried out including whole exome and Sanger sequencing (WES and SS) and loss-of-heterozygosity (LOH) testing for the respective loci. Immunohistochemistry (IHC) was used for the detection of proteins of interest. WES showed two germline variants in the APC and RASAL1 genes confirmed by SS. In MTC tissue only there was a RETvariant identified by SS; germline studies did not show any RETsequence changes. The pattern of tumors in this patient is unusual for either one of the APC- orRASAL1-associated neoplasms and her non-MEN 2-associated MTC contained a RET variant like other sporadic MTCs. As in other patients with more than one genetic variant predisposing to tumors, it is possible that this case represents a unique association.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:In-Process
[do] DOI:10.14310/horm.2002.1763

  9 / 39534 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29518761
[Au] Autor:Philippou A; Maridaki M; Tenta R; Koutsilieris M
[Ad] Address:Department of Experimental Physiology, Medical School, National and Kapodistrian University of Athens, Greece.
[Ti] Title:Hormonal responses following eccentric exercise in humans.
[So] Source:Hormones (Athens);16(4):405-413, 2017 Oct.
[Is] ISSN:1109-3099
[Cp] Country of publication:Greece
[La] Language:eng
[Ab] Abstract:OBJECTIVE: Mechanically overloaded muscle and its subsequent damage are strong stimuli for eliciting acute hormonal changes, while the muscle adaptation which occurs following exercise-induced muscle damage may involve complex hormonal responses before the completion of muscle regeneration. The purpose of this study was to investigate systemic responses of various hormones, as well as secreted proteins that are exercise-regulated and associated with muscle adaptation, for several days after eccentric exercise-induced muscle damage in humans. DESIGN: Nine young male volunteers performed 50 maximal eccentric muscle actions using the knee extensor muscles of both legs. Blood samples were drawn before and at 6, 48 and 120 hours post exercise and serum levels of growth hormone (GH), insulin-like growth factor binding protein-3 (IGFBP-3), cortisol, prolactin, thyroid-stimulating hormone (TSH), free thyroxine (fT4), irisin, follistatin and sclerostin were measured. Myoglobin (Mb) concentration and lactate dehydrogenase (LDH) activity were also evaluated as indirect markers of muscle damage. RESULTS: Significant alterations in Mb and LDH were observed over time after eccentric exercise (p=0.039-0.001). A late serum increase in fT4 and decrease in irisin levels, along with an early and persistent decrease in IGFBP-3 levels, were observed following the muscle-damaging exercise (p=0.049-0.016). GH, cortisol, prolactin, TSH, follistatin and sclerostin exhibited moderate changes during the recovery period after exercise, though without reaching statistical significance (p>0.05), while correlational analyses revealed significant associationsbetween GH and IGFBP-3, prolactin and sclerostin over time (p=0.049-0.001). CONCLUSIONS: The significant hormonal responses observed in this study may indicate their involvement in the regenerative mechanisms following muscle damage, potentially as part of a regulatory network to support a normal adaptation process after muscle-damaging exercise.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:In-Process
[do] DOI:10.14310/horm.2002.1761

  10 / 39534 MEDLINE  
              first record previous record
select
to print
Photocopy
Full text

[PMID]: 29518758
[Au] Autor:Karapanou O; Tzanela M; Vlassopoulou T; Kanaka-Gantenbein C
[Ad] Address:Department of Endocrinology, Diabetes and Metabolism, "Evangelismos" Hospital, Athens, Greece.
[Ti] Title:Differentiated thyroid cancer in childhood: a literature update.
[So] Source:Hormones (Athens);16(4):381-387, 2017 Oct.
[Is] ISSN:1109-3099
[Cp] Country of publication:Greece
[La] Language:eng
[Ab] Abstract:Differentiated thyroid cancer in childhood is rare. Apart from family history, radiation exposure is a major risk factor. Although its clinical course is quite aggressive with higher rates of lymph node and pulmonary metastases as compared to adults, the final outcome tends to be favorable with mortality rates less than 2%. We herein review the clinical picture, genetic background response to treatment and recurrence rates of differentiated thyroid cancer in children and young adolescents are thoroughly reviewed and the main differences with adult differentiated thyroid cancer are highlighted.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:In-Process
[do] DOI:10.14310/horm.2002.1758


page 1 of 3954 go to page                         
   


Refine the search
  Database : MEDLINE Advanced form   

    Search in field  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/PAHO/WHO - Latin American and Caribbean Center on Health Sciences Information