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[PMID]: 29447400
[Au] Autor:Ongsri P; Bunyaratavej S; Leeyaphan C; Pattanaprichakul P; Ongmahutmongkol P; Komoltri C; Kulthanan K
[Ad] Address:Naval Medical Department, Queen Sirikit Hospital, Royal Thai Navy, 163, Sukhumvit Road, Phlutaluang, Sattahip, Chonburi Province 20180, Thailand.
[Ti] Title:Prevalence and Clinical Correlation of Superficial Fungal Foot Infection in Thai Naval Rating Cadets.
[So] Source:Mil Med;, 2018 Feb 13.
[Is] ISSN:1930-613X
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Background: Superficial fungal foot infection is one of the most important dermatological diseases currently affecting military personnel. Many Thai naval rating cadets are found to suffer from superficial fungal foot infections and their sequels. Objective: To investigate prevalence, potent risk factors, responding pathogens and clinical correlation of superficial fungal foot infection in Thai naval rating cadets training in Naval rating school, Sattahip, Thailand. Materials and Methods: This cross-sectional study was performed in August 2015. Validated structured questionnaire was used regarding information about behaviors and clinical symptoms. Quality of life was assessed by Dermatology Quality of Life Index (DLQI) questionnaire and clinical presentation demonstrated by Athlete's foot severity score (AFSS). Laboratory investigations including direct microscopic examination and fungal culture were performed and recorded. All of the participants were informed and asked for their consent. Results: A total of 788 Thai naval rating cadets with a mean age of 19 yr were enrolled. There were 406 (51.5%) participants suspected of fungal skin infection from questionnaire screening. After clinical examination, 303 participants (38.5%) were found to have foot lesions (AFSS ≥1). Superficial fungal foot infection was diagnosed with microscopic examination and fungal culture in 57 participants, giving a point prevalence of 7.2%. Tinea pedis was diagnosed in 54 participants with the leading causative organism being Trichophyton mentagrophytes (52.8%). Other 3 participants were diagnosed as cutaneous candidiasis. Wearing combat shoes more than 8 h was found to be a predisposing factor (p = 0.029), taking a shower less than two times a day (p = 0.008), and wearing sandals during shower (p = 0.055) was found to be protective against infection. Most fungal feet infection cases noticed their feet abnormalities (p < 0.001) including scales (p < 0.001), vesicles (p = 0.003) and maceration at interdigital web spaces (p < 0.001). Mean DLQI in superficial fungal foot infection cases was 3.35. Participants who had foot lesions (AFSS ≥1) were concerned of their foots unpleasant odor demonstrated significantly higher mean DLQI than those without odor (4.2 vs. 2.28; p < 0.001). Conclusion: Superficial fungal foot infection is found as 7.2% of naval rating cadets. Wearing combat shoes more than 8 h was found to be a predisposing factor. In addition to skin manifestations including scales, vesicles, and maceration, superficial fungal foot infection also exhibited an unpleasant foot odor which affected quality of life. Self-foot-examination and life style modification should be promoted to prevent fungal infection.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:Publisher
[do] DOI:10.1093/milmed/usx187

  2 / 10174 MEDLINE  
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[PMID]: 29309591
[Au] Autor:Prescott GM; Patzke CL; Brody PM; Prescott WA
[Ad] Address:University at BuffaloSchool of Pharmacy and Pharmaceutical Sciences, Department of Pharmacy Practice, Buffalo, New York, USA.
[Ti] Title:Comparison of prescribing patterns between United States and Dominican Republic prescribers on short-term medical mission trips.
[So] Source:Int Health;10(1):27-32, 2018 Jan 01.
[Is] ISSN:1876-3405
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Background: Short-term medical missions (STMMs) have increased and are viewed as a way to extend care in low- and middle-income countries (LMICs). Although benefits may exist, visiting teams may lack insight into using medications safely and effectively. The primary objective was to assess prescribing differences between US-based and Dominican Republic (DR) healthcare providers on STMMs in the DR. Methods: A retrospective database review between January 2013 and 2015 was conducted. Data from US and DR groups were compared for differences in diagnoses, medication classes prescribed and prescriptions per patient. Results: The mean number of medical conditions diagnosed per patient in the DR (n=423) and US groups (n=1585) were 1.4±0.9 and 1.0±0.8, respectively. The diagnosis of infectious diseases was the same as non-communicable diseases. The DR group prescribed more medications at each patient encounter (mean 2.6 vs 2.2, respectively; p<0.001). The US group prescribed more antibiotics for respiratory infections (US 46.2% vs DR 25.0%; p=0.0001), used more metronidazole than albendazole alone for parasite infections (p=0.0022) and used more oral fluconazole for vaginal candidiasis (p<0.0001) and tinea infections (US 44.6%, DR 14.3%, respectively; p=0.0020). Conclusions: Although some significant prescribing differences exist between US and DR providers, many similarities were present. Visiting providers should understand the medication use system and disease burden before providing care in an LMIC.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:In-Data-Review
[do] DOI:10.1093/inthealth/ihx045

  3 / 10174 MEDLINE  
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[PMID]: 29292942
[Au] Autor:Lysell J
[Ad] Address:Karolinska Universitetssjukhuset Hudkliniken - Stockholm, Sweden Karolinska Universitetssjukhuset Hudkliniken - Stockholm, Sweden.
[Ti] Title:Psoriasis med debut i barndom och ungdom - Risken för samsjuklighet och påverkan på livskvaliteten måste uppmärksammas.
[So] Source:Lakartidningen;114, 2017 Nov 21.
[Is] ISSN:1652-7518
[Cp] Country of publication:Sweden
[La] Language:swe
[Ab] Abstract:Psoriasis in childhood and adolescence Psoriasis is a common inflammatory disease affecting 2-3% of the worldwide population. Onset in childhood and adolescence is not uncommon and around 30% of patients report onset before 20 years of age. Childhood psoriasis has been shown to differ in clinical presentation and in underlying genetics compared to adult psoriasis patients. To diagnose psoriasis in children with mild skin involvement may be difficult and the correct diagnosis is often delayed in children compared to adult psoriasis patients. Differential diagnoses include eczema, tinea and pityriasis rubra pilaris (PRP). Topical therapy is often effective but UV-therapy and systemic therapy is sometimes indicated.
[Mh] MeSH terms primary: Psoriasis
[Mh] MeSH terms secundary: Adolescent
Age of Onset
Child
Child, Preschool
Comorbidity
Humans
Infant
Psoriasis/epidemiology
Psoriasis/genetics
Psoriasis/pathology
Psoriasis/therapy
Quality of Life
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180306
[Lr] Last revision date:180306
[Js] Journal subset:IM
[Da] Date of entry for processing:180103
[St] Status:MEDLINE

  4 / 10174 MEDLINE  
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[PMID]: 29275029
[Au] Autor:Ouédraogo MS; Ouédraogo NA; Andonaba JB; Tapsoba GP; Somé NK; Sakandé J; Traoré FB; Maruani-Raphaël A; Niamba P; Traoré A
[Ad] Address:Centre hospitalier universitaire YalgadoOuédraogo, service de dermatologie-vénéréologie, 04 BP 8201 Ouagadougou 04, Ouagadougou, Burkina-Faso; Université Ouaga I Pr-Joseph-Ki-Zerbo, Ouagadougou, Burkina-Faso. Electronic address: sidnomam@yahoo.fr.
[Ti] Title:Tinea incognita chez un homme atteint de sida. [Tinea incognita in a HIV-infected male].
[So] Source:Presse Med;47(1):84-87, 2018 Jan.
[Is] ISSN:2213-0276
[Cp] Country of publication:France
[La] Language:fre
[Pt] Publication type:LETTER
[Em] Entry month:1712
[Cu] Class update date: 180305
[Lr] Last revision date:180305
[St] Status:In-Data-Review

  5 / 10174 MEDLINE  
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[PMID]: 29191265
[Au] Autor:Gobbato AAM; Gobbato CARS; Moreno RA; Antunes NJ; De Nucci G
[Ti] Title:Dapaconazole versus ketoconazole in the treatment of interdigital tinea pedis.
[So] Source:Int J Clin Pharmacol Ther;56(1):31-33, 2018 Jan.
[Is] ISSN:0946-1965
[Cp] Country of publication:Germany
[La] Language:eng
[Mh] MeSH terms primary: Antifungal Agents/therapeutic use
Imidazoles/therapeutic use
Ketoconazole/therapeutic use
Tinea Pedis/drug therapy
[Mh] MeSH terms secundary: Adult
Female
Humans
Male
Middle Aged
Ointments
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (1-(2-(2,4-dichlorophenyl)-2-(4-(trifluoromethyl)benzyloxy)ethyl)-1H-imidazole); 0 (Antifungal Agents); 0 (Imidazoles); 0 (Ointments); R9400W927I (Ketoconazole)
[Em] Entry month:1803
[Cu] Class update date: 180301
[Lr] Last revision date:180301
[Js] Journal subset:IM
[Da] Date of entry for processing:171202
[St] Status:MEDLINE
[do] DOI:10.5414/CP203124

  6 / 10174 MEDLINE  
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[PMID]: 29491232
[Au] Autor:Sakata Y; Ushigami T; Anzawa K; Mochizuki T
[Ad] Address:Department of Dermatology, Kanazawa Medical University.
[Ti] Title:Molecular epidemiology of Trichophyton tonsurans, the causative dermatophyte of the epidemic of tinea gladiatorum in Japan between 2011 and 2015.
[So] Source:Jpn J Infect Dis;, 2018 Feb 28.
[Is] ISSN:1884-2836
[Cp] Country of publication:Japan
[La] Language:eng
[Ab] Abstract:Trichophyton tonsurans, a major pathogen of tinea capitis and tinea corporis, has been isolated from players of contact sports in Japan. To understand the contemporary epidemic in Japan, the molecular types of 208 strains isolated between 2011 and 2015 were determined. Of these, 142 were isolated from practitioners of judo, 28 from wrestlers, seven from sumo wrestlers, and 31 from individuals with unknown backgrounds. Based on length polymorphisms of the non-transcribed spacer (NTS) region of the ribosomal RNA gene, these 208 strains could be divided into three subtypes, NTS I(204; 98.1%), II (three; 1.4%), and III(one; 0.5%). Additionally, single nucleotide polymorphisms (SNPs) and deletion/insertion profiles in the NTS region, length polymorphisms of the alkaline protease 1 gene, and a SNP in the carboxypeptidase Y gene were determined in 50 of NTS I strains isolated between 2011 and 2015, and in 10 strains isolated before 2005. All 60 strains were classified as the same molecular type, with a profile identical to that of type I b, a major type in the United States. These results indicated that NTS I strains isolated in Japan are clonal, irrespective of the type of sports activity.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180301
[Lr] Last revision date:180301
[St] Status:Publisher
[do] DOI:10.7883/yoken.JJID.2017.449

  7 / 10174 MEDLINE  
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[PMID]: 29352285
[Au] Autor:Han SS; Park GH; Lim W; Kim MS; Na JI; Park I; Chang SE
[Ad] Address:I Dermatology, Seoul, Korea.
[Ti] Title:Deep neural networks show an equivalent and often superior performance to dermatologists in onychomycosis diagnosis: Automatic construction of onychomycosis datasets by region-based convolutional deep neural network.
[So] Source:PLoS One;13(1):e0191493, 2018.
[Is] ISSN:1932-6203
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Although there have been reports of the successful diagnosis of skin disorders using deep learning, unrealistically large clinical image datasets are required for artificial intelligence (AI) training. We created datasets of standardized nail images using a region-based convolutional neural network (R-CNN) trained to distinguish the nail from the background. We used R-CNN to generate training datasets of 49,567 images, which we then used to fine-tune the ResNet-152 and VGG-19 models. The validation datasets comprised 100 and 194 images from Inje University (B1 and B2 datasets, respectively), 125 images from Hallym University (C dataset), and 939 images from Seoul National University (D dataset). The AI (ensemble model; ResNet-152 + VGG-19 + feedforward neural networks) results showed test sensitivity/specificity/ area under the curve values of (96.0 / 94.7 / 0.98), (82.7 / 96.7 / 0.95), (92.3 / 79.3 / 0.93), (87.7 / 69.3 / 0.82) for the B1, B2, C, and D datasets. With a combination of the B1 and C datasets, the AI Youden index was significantly (p = 0.01) higher than that of 42 dermatologists doing the same assessment manually. For B1+C and B2+ D dataset combinations, almost none of the dermatologists performed as well as the AI. By training with a dataset comprising 49,567 images, we achieved a diagnostic accuracy for onychomycosis using deep learning that was superior to that of most of the dermatologists who participated in this study.
[Mh] MeSH terms primary: Diagnosis, Computer-Assisted
Neural Networks (Computer)
Onychomycosis/diagnosis
[Mh] MeSH terms secundary: Adult
Aged
Algorithms
Area Under Curve
Artificial Intelligence
Databases, Factual
Dermatologists
Female
Foot Dermatoses/diagnosis
Foot Dermatoses/pathology
Hand Dermatoses/diagnosis
Hand Dermatoses/pathology
Humans
Image Interpretation, Computer-Assisted
Machine Learning
Male
Middle Aged
Onychomycosis/pathology
Young Adult
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180226
[Lr] Last revision date:180226
[Js] Journal subset:IM
[Da] Date of entry for processing:180121
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191493

  8 / 10174 MEDLINE  
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[PMID]: 29478279
[Au] Autor:Xia XJ; Zhang Y; Zhong Y; Sang B; Li QP; Wang M; Lv WW; Zhi HL; Wang XD; Shen H; Liu ZH
[Ad] Address:Department of Dermatology, Affiliated Third Hospital of Hangzhou, Anhui Medical University.
[Ti] Title:Novel in vivo observations of scrotal Nannizzia gypsea infection.
[So] Source:Br J Dermatol;, 2018 Feb 25.
[Is] ISSN:1365-2133
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Tinea cruris is a common dermatophytosis, which usually firstly involved the intertriginous fold near the scrotum. Although dermatophytes may colonize the scrotum, they typically do not infect scrotal skin. However, tinea of scrotum is seldom reported as a specific type of Microsporum gypseum infection, presenting as white-paint-dot appearance, scutular-like or pseudomembranous-like lesions in immunocompromised or immunocompetent patients . According to the newest taxonomy, M. gypseum is now called Nannizia gypsea . Herein we report novel in vivo observations of five cases of scrotal tinea caused by N. gypsea (formerly Microsporum gypseum) in immunocompetent patients. This article is protected by copyright. All rights reserved.
[Pt] Publication type:LETTER
[Em] Entry month:1802
[Cu] Class update date: 180225
[Lr] Last revision date:180225
[St] Status:Publisher
[do] DOI:10.1111/bjd.16474

  9 / 10174 MEDLINE  
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[PMID]: 29468277
[Au] Autor:Metzner M; Schwarz T; Brasch J
[Ad] Address:Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Rosalind-Franklin-Str. 7, 24105, Kiel, Deutschland. mmetzner@dermatology.uni-kiel.de.
[Ti] Title:Tinea faciei durch Nannizzia persicolor : Ein unterdiagnostizierter Dermatophyt? [Tinea faciei caused by Nannizzia persicolor : An underdiagnosed dermatophyte?]
[So] Source:Hautarzt;, 2018 Feb 21.
[Is] ISSN:1432-1173
[Cp] Country of publication:Germany
[La] Language:ger
[Ab] Abstract:We report on a tinea faciei caused by Nannizzia (N.) persicolor. The 4­year-old boy had probably been infected by a guinea pig. Unambiguous infections caused by N. persicolor are rarely seen in Germany; however, this zoophilic and geophilic dermatophyte may only be rarely identified due to its resemblance to Trichophyton (T.) mentagrophytes. Therefore, the diagnostic attributes of N. persicolor and its differentiation from T. mentagrophytes are described. Particularly in case of contact with rodents, N. persicolor should be kept in mind.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180222
[Lr] Last revision date:180222
[St] Status:Publisher
[do] DOI:10.1007/s00105-018-4136-3

  10 / 10174 MEDLINE  
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[PMID]: 29464746
[Au] Autor:Oshinsky S; Baum S; Huszar M; Debby A; Barzilai A
[Ad] Address:Department of Dermatology, Sheba Medical Centre.
[Ti] Title:Basal Cell Carcinoma Induced by Therapeutic Radiation for Tinea Capitis - Clinical Pathological Study.
[So] Source:Histopathology;, 2018 Feb 21.
[Is] ISSN:1365-2559
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:AIMS: An increased prevalence of aggressive histological subtypes, such as the micronodular and morpheaform, has been seen, irrespective of the clinical course, in basal cell carcinoma (BCC) following irradiation for tinea capitis. The aim of this study was to assess the histopathological features of BCCs among patients irradiated for tinea capitis and correlate them with the clinical course. METHODS AND RESULTS: The medical records and BCC biopsy specimens of individuals who were previously irradiated for tinea capitis were revised. Demographic data and clinical characteristics were retrieved. Biopsy specimens were evaluated for histological subtype classification and additional histopathological features. A telephone survey was conducted to assess the clinical behaviour of the tumours. Thirty-one patients (17 male, 14 female) were included. The average age at time of first biopsy was 56 years. The total number of lesions was 185, with 80% of subjects showing multiple lesions. Nodular subtype was the most prevalent, followed by superficial, micronodular, and mixed tumours. Third of the BCC could be classified as aggressive histologically. Stromal fibroplasia and melanin deposits were common. There was no mortality related to BCC. None of the 17 patients who completed the survey had evidence of local invasiveness or metastases. CONCLUSIONS: BCCs following radiation therapy for tinea capitis show unique histological characteristics related to aggressive behaviour. These aggressive features did not reflect the clinical behaviour in the current cohort. This article is protected by copyright. All rights reserved.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180221
[Lr] Last revision date:180221
[St] Status:Publisher
[do] DOI:10.1111/his.13497


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