Database : MEDLINE
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[PMID]: 28542534
[Au] Autor:González-Andrade B; Santos-Lartigue R; Flores-Treviño S; Ramirez-Ochoa NS; Bocanegra-Ibarias P; Huerta-Torres FJ; Mendoza-Olazarán S; Villarreal-Treviño L; Camacho-Ortiz A; Villarreal-Vázquez H; Garza-González E
[Ad] Address:Servicio de Otorrinolaringología, Hospital Universitario "Dr. José Eleuterio González", Universidad Autónoma de Nuevo León, Monterrey, Nuevo Leon, Mexico.
[Ti] Title:The carriage of interleukin-1B-31*C allele plus Staphylococcus aureus and Haemophilus influenzae increases the risk of recurrent tonsillitis in a Mexican population.
[So] Source:PLoS One;12(5):e0178115, 2017.
[Is] ISSN:1932-6203
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:The aim of the present study was to estimate the relative contribution of immunogenetic and microbiological factors in the development of recurrent tonsillitis in a Mexican population. Patients (n = 138) with recurrent tonsillitis and an indication of tonsillectomy (mean age: 6.05 years ± 3.00; median age: 5 years, female: 58; age range: 1-15 years) and 195 non-related controls older than 18 years and a medical history free of recurrent tonsillitis were included. To evaluate the microbial contribution, tonsil swab samples from both groups and extracted tonsil samples from cases were cultured. Biofilm production of isolated bacteria was measured. To assess the immunogenetic component, DNA from peripheral blood was genotyped for the TNFA-308G/A single-nucleotide polymorphism (SNP) and for the IL1B -31C/T SNP. Normal microbiota, but no pathogens or potential pathogens, were identified from all control sample cultures. The most frequent pathogenic species detected in tonsils from cases were Staphylococcus aureus (48.6%, 67/138) and Haemophilus influenzae (31.9%, 44/138), which were found more frequently in patient samples than in samples from healthy volunteers (P < 0.0001). Importantly, 41/54 (75.9%) S. aureus isolates were biofilm producers (18 weak and 23 strong), whereas 17/25 (68%) H. influenzae isolates were biofilm producers (10 weak, and 7 strong biofilm producers). Patients with at least one copy of the IL1B-31*C allele had a higher risk of recurrent tonsillitis (OR = 4.03; 95% CI = 1.27-14.27; P = 0.013). TNFA-308 G/A alleles were not preferentially distributed among the groups. When considering the presence of IL1B-31*C plus S. aureus, IL1B-31*C plus S. aureus biofilm producer, IL1B-31*C plus H. influenzae or IL1B-31*C plus H. influenzae biofilm producer, the OR tended to infinite. Thus, the presence of IL1B-31*C allele plus the presence of S. aureus and/or H. influenzae could be related to the development of tonsillitis in this particular Mexican population.
[Mh] MeSH terms primary: Carrier State/microbiology
Haemophilus Infections/etiology
Interleukin-1beta/genetics
Staphylococcal Infections/etiology
Tonsillitis/etiology
[Mh] MeSH terms secundary: Adolescent
Adult
Aged
Alleles
Biofilms
Carrier State/immunology
Case-Control Studies
Child
Child, Preschool
Female
Haemophilus Infections/genetics
Haemophilus Infections/microbiology
Haemophilus influenzae/isolation & purification
Humans
Immunogenetic Phenomena
Infant
Male
Mexico
Microbiota
Middle Aged
Recurrence
Risk Factors
Staphylococcal Infections/genetics
Staphylococcal Infections/microbiology
Staphylococcus aureus/isolation & purification
Tonsillitis/genetics
Tonsillitis/microbiology
Tumor Necrosis Factor-alpha/genetics
Young Adult
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (IL1B protein, human); 0 (Interleukin-1beta); 0 (Tumor Necrosis Factor-alpha)
[Em] Entry month:1709
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[Js] Journal subset:IM
[Da] Date of entry for processing:170525
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0178115

  2 / 7449 MEDLINE  
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[PMID]: 28093800
[Au] Autor:Hosokawa T; Yamada Y; Tanami Y; Hattori S; Sato Y; Hosokawa M; Oguma E
[Ad] Address:Department of Radiology, Saitama Children's Medical Center, Saitama, Japan.
[Ti] Title:Evaluation of the Normal Tonsils in Pediatric Patients With Ultrasonography.
[So] Source:J Ultrasound Med;36(5):1029-1036, 2017 May.
[Is] ISSN:1550-9613
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:OBJECTIVES: To evaluate how well the tonsils can be viewed, in addition to echogenicity, using ultrasound, and to compare these results between children younger and older than the age of 3. METHODS: We evaluated the tonsils of 99 patients (72.0 ± 59.1 months) by ultrasound. Ultrasound scans of both the left and right side, in both the transverse and longitudinal planes, were obtained. Images were scored with one of four grades according to how well the tonsil border could be distinguished, 0 being the worst and 3 being the best. Grades 2 or 3 (>50% of the tonsil border was detectable) in both tonsils, in either the transverse or longitudinal image, were considered "evaluable." Echogenicity was designated as imperceptible, low echoic, or striated in appearance. Statistical analysis was performed using the Mann-Whitney U test. RESULTS: Bilateral tonsils were evaluable in 96.0% (96/99) of cases. The mean grades were 2.44 ± 0.65/2.03 ± 0.68 in the right transverse/longitudinal images, and 2.40 ± 0.59/2.12 ± 0.73 in the left transverse/longitudinal images. The grades in children older than the age of 3 were significantly higher than those in younger patients (all P < .05). Echogenicity classification on the right and left side revealed a striated appearance in 97.0% (96/99) and 90.0% (89/99) of cases, respectively. CONCLUSIONS: The tonsils of almost all pediatric patients could be evaluated by ultrasound, particularly for patients older than 3 years. Additionally, a striated pattern of the tonsils was observed in most cases.
[Mh] MeSH terms primary: Palatine Tonsil/anatomy & histology
Ultrasonography/methods
[Mh] MeSH terms secundary: Adolescent
Child
Child, Preschool
Female
Humans
Infant
Infant, Newborn
Male
Reference Values
Reproducibility of Results
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171102
[Lr] Last revision date:171102
[Js] Journal subset:IM
[Da] Date of entry for processing:170117
[St] Status:MEDLINE
[do] DOI:10.7863/ultra.16.05083

  3 / 7449 MEDLINE  
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[PMID]: 28961815
[Au] Autor:Glinz D; Leon Reyes S; Saccilotto R; Widmer AF; Zeller A; Bucher HC; Hemkens LG
[Ad] Address:Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, and University of Basel, Basel, Switzerland.
[Ti] Title:Quality of antibiotic prescribing of Swiss primary care physicians with high prescription rates: a nationwide survey.
[So] Source:J Antimicrob Chemother;72(11):3205-3212, 2017 Nov 01.
[Is] ISSN:1460-2091
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Objectives: To assess the quality of antibiotic prescribing of Swiss primary care physicians with high prescription rates. Methods: In January 2015, we mailed a structured questionnaire to 2900 primary care physicians in Switzerland. They were included in a nationwide pragmatic randomized controlled trial on routine antibiotic prescription monitoring and feedback based on health insurance claims data. We asked them to record the diagnosis and antibiotic treatment for 44 consecutive patients with the most common conditions associated with antibiotic prescribing in primary care. We evaluated if the disease-specific antibiotic prescribing and the proportion of non-recommended antibiotics used, in particular quinolones, were within 'acceptable ranges' using adapted European Surveillance of Antimicrobial Consumption (ESAC) quality indicators. Results: Two hundred and fifty physicians (8.6%) responded, providing 9961 patient records. Responders were similar to the entire physician population. Overall, antibiotics were prescribed to 32.1% of patients. For tonsillitis/pharyngitis, acute otitis media, acute rhinosinusitis and acute bronchitis the acceptable maximum of antibiotic prescriptions was exceeded by 24.4%, 49.6%, 27.4% and 11.5%, respectively. The proportion of non-recommended antibiotics was for all diagnoses above the recommended maximum of 20% (31.5%-88.7% across all conditions). Quinolones were prescribed to 37.2% of women with urinary tract infections, substantially exceeding the recommended maximum of 5%. Conclusions: Antibiotic prescribing quality of Swiss primary care physicians with high prescription rates is low according to the indicators used, with substantial overtreatment of tonsillitis/pharyngitis, acute rhinosinusitis, acute otitis media and acute bronchitis. Routine nationwide and continuous monitoring of antibiotic use and specific interventions are warranted to improve prescribing in primary care.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1709
[Cu] Class update date: 171031
[Lr] Last revision date:171031
[St] Status:In-Process
[do] DOI:10.1093/jac/dkx278

  4 / 7449 MEDLINE  
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[PMID]: 28980591
[Au] Autor:Yushchuk ND; Kryukov AI; Turovsky AB; Popova IA; Savostikova MV
[Ad] Address:A.I. Evdokimov Moscow State Medical Stomatological, Moscow, Russia, 127473.
[Ti] Title:Znachenie persistiruiushchei virusnoi infektsii semeistv Herpes viridae i Papilloma viridae pri khronicheskikh vospalitel'nykh zabolevaniiakh glotki. [The role of persistent viral infections with Herpes viridae and Papilloma viridae associated with chronic inflammatory pathology of the oropharynx].
[So] Source:Vestn Otorinolaringol;82(4):25-28, 2017.
[Is] ISSN:0042-4668
[Cp] Country of publication:Russia (Federation)
[La] Language:rus
[Ab] Abstract:The high prevalence of chronic inflammatory oropharyngeal pathologies and a large variety of specific pathogenetic features of the persistent viral infections caused by the species of the families Herpesviridae and Papillomaviridae as etiological agents of the disease suggest the necessity of investigations with a view to evaluating the clinical significance of persistent viral infections with Herpesviridae and Papillomaviridae species in the patients presenting with chronic inflammatory oropharyngreal pathology. The objective of the present study was to elucidate the prevalence and clinical significance of viral infections caused by the pathogenic agents belonging to the families Herpesviridae and Papillomaviridae in the patients presenting with chronic inflammatory pathology of the oropharynx. We examined two groups of patients one of which was comprised of 174 subjects suffering from chronic inflammatory oropharyngeal pathologies while the other consisted of 31 healthy people. All the patients in both groups underwent the general clinical examination, real-time PCR diagnostics of the viral infections with Herpes viridae and Papilloma viridae using the scrapings of oropharyngeal mucosa, and the microbiological study of the oropharynx secretion. The study has demonstrated the high frequency of viral infections caused by Herpesviridae and Papillomaviridae species in the patients with chronic inflammatory pathology of the oropharynx in comparison with the control group of healthy subjects (81.03% and 45.16% respectively). It was shown that the certain types of pathological conditions were specifically associated with the concrete forms of viral infections. The results of the cytological study give evidence that all (100%) the patients with chronic inflammatory oropharyngeal pathologies had the specific changes in epithelium in the combination with the non-specific alterations. 63.6% of the patients with chronic inflammatory oropharyngeal pathologies and negative results of viral diagnostics using the real-time PCR technology were found to have non-specific changes in epithelium as opposed to 25.8% of the healthy subjects. The correlation analysis of the results of real-time PCR diagnostics and the bacteriological study showed that 45.1% of the carriers of the Epstein-Barr virus were infected with S. pneumoniae and 23.2% with Kl..pneumoniae whereas the mixed infection was documented in 31.1% of the EBV carriers. Moreover, 10.98% of such patients presented with Candida albicans infection whereas. 54.5% and 27.3% of the patients with HHV-6 were diagnosed as having S. aureus and S. pneumoniae infection respectively; the combined flora was found in 18.2% of such patients.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171031
[Lr] Last revision date:171031
[St] Status:In-Process
[do] DOI:10.17116/otorino201782425-28

  5 / 7449 MEDLINE  
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[PMID]: 28980588
[Au] Autor:Kryukov AI; Tsarapkin GY; Ivanchikov AA; Tovmasyan AS; Arzamazov SG; Panasov SA; Gorovaya EV; Kakorin AS
[Ad] Address:L.I. Sverzhevskiy Research Institute of Clinical Otorhinolaryngology, Moscow Health Department, Moscow, Russia, 117152.
[Ti] Title:Identifikatsiia osobennostei topografii sosudov shei v profilaktike krovotechenii pri tonzilléktomii. [Identification of the specific topographic features of the neck vessels for the prevention of bleedings during tonsillectomy].
[So] Source:Vestn Otorinolaringol;82(4):16-18, 2017.
[Is] ISSN:0042-4668
[Cp] Country of publication:Russia (Federation)
[La] Language:rus
[Ab] Abstract:The objective of the present work was to study syntopy of the large neck vessels in relation to the capsule of palatine tonsils with the use of the MRI technology. A total of 109 patients (218 palatine tonsils) presenting with chronic tonsillitis were available for the examination including 64 women and 45 men at the age varying from 15 to 54 years. All of them underwent MRI-guided vascular visualization in the paratonsillar region together with the measurements of the vessels extending to the capsule of the palatine tonsils at the level of the upper and lower poles, and also close to the mid-third of each palatine tonsil. The distance from the external carotid artery to the upper and lower poles of the palatine tonsils was found to be 17.1±1.01 mm and 10.3±0.18 mm respectively and in the mid-third the palatine tonsil 10.7±0.12 mm; the distance from the internal carotid artery to the upper and low poles of the palatine tonsil amounted to 14.5±0.84 mm and 16.8±0.77 mm respectively while that to the mid-third of the palatine tonsil was 15.3±0.07 mm. The branches of the external carotid artery feeding the palatine tonsils are the most frequent sources of bleedings; the following measurements were obtained: the maxillary artery 16.4±0.43 mm (17.4%) - the upper pole 9.6±0.02 mm (46.2%), the mid-third of the palatine tonsil 18.5±0.74 mm (29.5%) - the lower pole; the lingual artery 4.7±0.02 mm (6.8%) - the mid-third of the palatine tonsil, 6.2±0.82 mm (56.8%) - the lower pole; facial artery: 4.2±0.01 mm (0.76%) - the mid-third of the palatine tonsil; the occipital artery 25.6±0.12 mm (19%) - the upper pole; 14.8±0.11 mm (18.9%) - the mid-third of the palatine tonsil 9.56±0.12 mm (3.8%) - the lower pole; the tonsillar artery 1.88±0.01 mm (9.8%) - the upper pole; 2.51±0.01 mm (23%) - the mid-third of the palatine tonsil; 2.12±0.01 mm (11%) - the lower pole. The distance from the internal jugular vein to the capsule of the palatine tonsils in the region of the upper pole of the palatine tonsil was 28.3±1.01 mm, in the lower pole region 26.6±1.54 mm, and in the region of the mid-third of the palatine tonsil 22.7±1.24 mm. It is concluded that the results of the present study may be useful for the planning of the surgical strategy for the treatment of the patients presenting with chronic tonsillitis and for the prevention of hemorrhagic complications of tonsillectomy.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171031
[Lr] Last revision date:171031
[St] Status:In-Process
[do] DOI:10.17116/otorino201782416-18

  6 / 7449 MEDLINE  
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[PMID]: 29072654
[Au] Autor:Soldatsky YL; Denisova OA; Bulynko SA
[Ad] Address:N.I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia, 117997; Morozovskaya City Children's Clinical Hospital, Moscow Health Department, Moscow, Russia, 119049.
[Ti] Title:Osobennosti anamneza i étiologii abstsessov glotki u detei. [The specific features of the past medical history and etiology of pharyngeal abscess in the children].
[So] Source:Vestn Otorinolaringol;82(5):12-14, 2017.
[Is] ISSN:0042-4668
[Cp] Country of publication:Russia (Federation)
[La] Language:rus
[Ab] Abstract:The present study was undertaken for the purpose of elucidating the specific features of the past medical history and the etiological factors responsible for the development of tonsillogenic pharyngeal abscesses in the children. We performed the retrospective analysis of the medical histories of 291 children presenting with this condition who had been admitted for the treatment to the ENT Department of the Morozovskzya City Children's Clinical Hospital during the period from January till December 2015. The study has demonstrated the following most common shortcomings of the outpatient treatment of the patients suffering from chronic tonsillitis at the stage preceding formation of paratonsillar abscess: inadequate antibacterial therapy of acute chronic tonsillitis or its exacerbation and limited indications for tonsillectomy at the level of the outpatient treatment. The leading role in the etiology of tonsillogenic pharyngeal abscesses in the children is played by beta-hemolytic Streptococcus of group A. It is concluded that the medical history suggesting past paratonsillar abscess is the absolute indication for the subsequent tonsillectomy in the children of any age.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171026
[Lr] Last revision date:171026
[St] Status:In-Data-Review
[do] DOI:10.17116/otorino201782512-14

  7 / 7449 MEDLINE  
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[PMID]: 29071850
[Au] Autor:Bian LL; Wang FW; Yang Y; Zhang L; Liu CX; Zhang JH; Zheng WK
[Ad] Address:Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
[Ti] Title:[Systematic review of effectiveness and safety of pudilan Xiaoyan oral liquid in treating pediatric suppurative tonsilitis].
[So] Source:Zhongguo Zhong Yao Za Zhi;42(8):1482-1488, 2017 Apr.
[Is] ISSN:1001-5302
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:The review aims to assess the effectiveness and safety Pudilan Xiaoyan oral liquid in treating pediatric suppurative tonsillitis systematically through searching relevant electronic database and collecting relevant literature. Meta-analysis was performed with the RevMan 5.3 software. Eighteen RCTs of 1 883 patients of pediatric suppurative tonsillitis were included. Meta-analysis showed that: compared with the application of antibiotics alone, combined with Pudilan can effectively improve the treatment of pediatric suppurative tonsillitis in efficacy rate and shorten the time of recovering normal temperature, the time of tonsil purulent discharge and can also reduce the extinction time of sore throat, antiadoncus or congestion subsided and appetite recovery. There was no severe adverse reaction during the treatment. Compared with the application of antibiotics alone, combined with Pudilan may be more effective and safe in the treatment of pediatric suppurative tonsillitis, which can not be strongly proved at present for lack of studies with high quality.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171026
[Lr] Last revision date:171026
[St] Status:In-Process
[do] DOI:10.19540/j.cnki.cjcmm.2017.0045

  8 / 7449 MEDLINE  
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[PMID]: 29071844
[Au] Autor:Fan CZ; Miao Q; Zhang Q; Fan MR; Liao X; Liu J; Li PH; Cong XD; Wang B
[Ad] Address:Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China.
[Ti] Title:[Advantages and evidence of Chinese medicine in prevention and treatment of adult acute tonsillitis].
[So] Source:Zhongguo Zhong Yao Za Zhi;42(8):1430-1438, 2017 Apr.
[Is] ISSN:1001-5302
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:Though evaluation and analysis on the relevant literatures at home and abroad in recent years, the total number of retrieved literature was 2 664. According to the inclusion criteria and exclusion criteria,the literatures were screened out, and the results were as follows:374 literatures. To analyse the advantages and evidence of Chinese medicine in the prevention and treatment of adult acute tonsillitis. It is found to be effective, convenient and practical for the treatment of acute tonsillitis by traditional Chinese medicine (TCM) like treatment according to syndrome differentiation, Chinese patent drug, self Chinese medicine prescription and external treatment. TCM has obvious advantages in the prevention and treatment of acute tonsillitis, has the function of supplementing or substituting antibiotics, and has the function of regulating the defense function of organism.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171026
[Lr] Last revision date:171026
[St] Status:In-Process
[do] DOI:10.19540/j.cnki.cjcmm.2017.0039

  9 / 7449 MEDLINE  
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[PMID]: 29023596
[Au] Autor:González-Andrade B; Santos-Lartigue R; Flores-Treviño S; Ramirez-Ochoa NS; Bocanegra-Ibarias P; Huerta-Torres FJ; Mendoza-Olazarán S; Villarreal-Treviño L; Camacho-Ortiz A; Villarreal-Vázquez H; Garza-González E
[Ti] Title:Correction: The carriage of interleukin-1B-31*C allele plus Staphylococcus aureus and Haemophilus influenzae increases the risk of recurrent tonsillitis in a Mexican population.
[So] Source:PLoS One;12(10):e0186627, 2017.
[Is] ISSN:1932-6203
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:[This corrects the article DOI: 10.1371/journal.pone.0178115.].
[Pt] Publication type:PUBLISHED ERRATUM
[Em] Entry month:1710
[Cu] Class update date: 171022
[Lr] Last revision date:171022
[St] Status:In-Data-Review
[do] DOI:10.1371/journal.pone.0186627

  10 / 7449 MEDLINE  
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[PMID]: 29053625
[Au] Autor:Hu M; Yu Z; Wang J; Fan W; Liu Y; Li J; Xiao H; Li Y; Peng W; Wu C
[Ad] Address:College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. hmbcdtcm@163.com.
[Ti] Title:Traditional Uses, Origins, Chemistry and Pharmacology of Bombyx batryticatus: A Review.
[So] Source:Molecules;22(10), 2017 Oct 20.
[Is] ISSN:1420-3049
[Cp] Country of publication:Switzerland
[La] Language:eng
[Ab] Abstract:( ), a well-known traditional animal Chinese medicine, has been commonly used in China for thousands of years. The present paper reviewed advances in traditional uses, origin, chemical constituents, pharmacology and toxicity studies of . The aim of the paper is to provide more comprehensive references for modern study and application. In Traditional Chinese Medicine (TCM) culture, drugs containing have been used to treat convulsions, headaches, skin prurigo, scrofula, tonsillitis and fever. Many studies indicate contains various compounds, including protein and peptides, fatty acids, flavonoids, nucleosides, steroids, coumarin, polysaccharide and others. Numerous investigations also have shown that extracts and compounds from exert a wide spectrum of pharmacological effects both in vivo and in vitro, including effects on the nervous system, anticoagulant effects, antitumor effects, antibacterial and antifungal effects, antioxidant effects, hypoglycemic effects, as well as other effects. However, further studies should be undertaken to investigate bioactive compounds (especially proteins and peptides), toxic constituents, using forms and the quality evaluation and control of . Furthermore, it will be interesting to study the mechanism of biological activities and structure-function relationships of bioactive constituents in .
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1710
[Cu] Class update date: 171020
[Lr] Last revision date:171020
[St] Status:In-Process


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