Database : MEDLINE
Search on : twins [Words]
References found : 39639 [refine]
Displaying: 1 .. 10   in format [Detailed]

page 1 of 3964 go to page                         

  1 / 39639 MEDLINE  
              next record last record
select
to print
Photocopy
Full text

[PMID]: 29508907
[Au] Autor:Widen EM
[Ad] Address:Department of Nutritional Sciences, University of Texas at Austin, Austin, TX.
[Ti] Title:Weight Gain for Gestational-Age Charts in Dichorionic Twins: Tool for Establishing Optimal Weight Gain in Twin Pregnancies.
[So] Source:Paediatr Perinat Epidemiol;, 2018 Mar 06.
[Is] ISSN:1365-3016
[Cp] Country of publication:England
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180311
[Lr] Last revision date:180311
[St] Status:Publisher
[do] DOI:10.1111/ppe.12460

  2 / 39639 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29391266
[Au] Autor:Wod M; Hallas J; Andersen K; García Rodríguez LA; Christensen K; Gaist D
[Ad] Address:Unit of Epidemiology, Biostatistics, and Biodemography, and the Danish Twin Registry, and the Danish Aging Research Center, Department of Public Health, University of Southern Denmark, Odense, Denmark.
[Ti] Title:Lack of Association Between Proton Pump Inhibitor Use and Cognitive Decline.
[So] Source:Clin Gastroenterol Hepatol;, 2018 Jan 31.
[Is] ISSN:1542-7714
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND & AIMS: Studies of association between use of proton pump inhibitors (PPI) and dementia have yielded conflicting results. We investigated the effects of PPIs on cognitive decline in a study of middle-aged and elderly twins in Denmark. METHODS: In a prospective study, we collected data from surveys of middle-aged individuals (46-67 years old; the Middle Aged Danish Twin study) and older individuals (the Longitudinal Study of Aging Danish Twins) who underwent cognitive assessments (a 5-component test battery) over a 10-year period (middle-age study, n = 2346) or a 2-year period (longitudinal study of aging: n = 2475). We determined cumulative use of PPIs 2 years prior study enrollment and during follow up, in defined daily doses (DDDs) of PPIs, using data from a nationwide prescription register. Multi-variable linear regression models were used to examine associations between cumulative PPI use and a composite score of cognitive function at baseline and decreases in scores during the follow-up periods. RESULTS: Use of PPIs before study enrollment was associated with a slightly lower mean cognitive score at baseline in the middle age study. The adjusted difference in mean score of individuals with high consumption of PPIs (≥400 DDD) was lower than that of non-users in the middle-age study (mean crude score for high PPI use, 43.4 ± 13.1 vs for non-use, 46.8 ± 10.2; adjusted difference of 0.69 points; 95% CI, -4.98 to 3.61). In the longitudinal study of aging twins, individuals with high consumption of PPI had higher adjusted scores than non-users (mean crude score for high PPI use, 35.2 ± 10.8 vs for non-use, 36.2 ± 11.1; adjusted difference of 0.95 points; 95% CI, -1.88 to 3.79). In analyses of cognitive decline, among individuals with high consumption of PPIs in the longitudinal study of aging, the adjusted mean difference between baseline score and follow-up score was lower than that of non-users (mean crude score for high PPI use at baseline, 36.6 ± 10.1 and at follow up, 34.3 ± 12.3 vs for non-use at baseline, 38.1 ± 10.5 and at follow up, 37.6 ± 11.3; adjusted difference of 1.22 points; 95% CI, -3.73 to 1.29). In the middle-age study, users with the highest consumption of PPIs (≥1600 DDD) had slightly less cognitive decline than non-users (baseline mean crude score for high PPI use, 43.4 ± 10.1 and follow-up mean crude score, 41.3 ± 9.7 vs baseline score of 49.1 ± 10.2 for non-users and follow-up score of 46.3 ± 9.9 for non-users; adjusted difference of 0.94 points; 95% CI, -1.63 to 3.50). No stated differences in scores between PPI users and non-users were significant. CONCLUSIONS: In analyzing data from 2 large population-based studies of twins in Denmark, we found no association between PPI use and cognitive decline.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180310
[Lr] Last revision date:180310
[St] Status:Publisher

  3 / 39639 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29369039
[Au] Autor:Cecilione JL; Rappaport LM; Hahn SE; Anderson AE; Hazlett LE; Burchett JR; Moore AA; Savage JE; Hettema JM; Roberson-Nay R
[Ad] Address:Department of Psychiatry,Virginia Commonwealth University,Richmond,Virginia,USA.
[Ti] Title:Genetic and Environmental Contributions of Negative Valence Systems to Internalizing Pathways.
[So] Source:Twin Res Hum Genet;21(1):12-23, 2018 Feb.
[Is] ISSN:1832-4274
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:The genetic and environmental contributions of negative valence systems (NVS) to internalizing pathways study (also referred to as the Adolescent and Young Adult Twin Study) was designed to examine varying constructs of the NVS as they relate to the development of internalizing disorders from a genetically informed perspective. The goal of this study was to evaluate genetic and environmental contributions to potential psychiatric endophenotypes that contribute to internalizing psychopathology by studying adolescent and young adult twins longitudinally over a 2-year period. This report details the sample characteristics, study design, and methodology of this study. The first wave of data collection (i.e., time 1) is complete; the 2-year follow-up (i.e., time 2) is currently underway. A total of 430 twin pairs (N = 860 individual twins; 166 monozygotic pairs; 57.2% female) and 422 parents or legal guardians participated at time 1. Twin participants completed self-report surveys and participated in experimental paradigms to assess processes within the NVS. Additionally, parents completed surveys to report on themselves and their twin children. Findings from this study will help clarify the genetic and environmental influences of the NVS and their association with internalizing risk. The goal of this line of research is to develop methods for early internalizing disorder risk detection.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180311
[Lr] Last revision date:180311
[St] Status:In-Data-Review
[do] DOI:10.1017/thg.2017.72

  4 / 39639 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29523586
[Au] Autor:Halling C; Corcoran JD
[Ad] Address:Department of Childrens Health, University of Texas Southwestern, Dallas, Texas, USA.
[Ti] Title:Little and large: the effects of twin growth discordance.
[So] Source:Arch Dis Child Fetal Neonatal Ed;, 2018 Mar 09.
[Is] ISSN:1468-2052
[Cp] Country of publication:England
[La] Language:eng
[Pt] Publication type:EDITORIAL
[Em] Entry month:1803
[Cu] Class update date: 180310
[Lr] Last revision date:180310
[St] Status:Publisher

  5 / 39639 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29523478
[Au] Autor:Burri A; Ogata S
[Ad] Address:Health and Rehabilitation Research Institute, Auckland University of Technology, Auckland, New Zealand; European Institute for Sexual Health, Hamburg, Germany. Electronic address: andrea.burri@kcl.ac.uk.
[Ti] Title:Stability of Genetic and Environmental Influences on Female Sexual Functioning.
[So] Source:J Sex Med;, 2018 Mar 06.
[Is] ISSN:1743-6109
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:BACKGROUND: Genetic factors have been implicated in the etiology of female sexual dysfunction. Yet, how much the dynamic nature of sexual functioning is influenced by changes in genetic and/or environmental factors remains unknown. AIM: To explore temporal stability of genetic and environmental influences on female sexual functioning over a 4-year period. METHODS: Data on desire, arousal, lubrication, orgasm, satisfaction, and pain were collected in 2009 and 2013 using the Female Sexual Function Index and were available for 1,209 British twin women. OUTCOMES: To track the stability of genetic influences the Female Sexual Function Index sub-domain and total scores were subject to multivariate twin analyses for repeated measures. RESULTS: Desire showed a lower heritability at follow-up (37% vs 14%) whereas for arousal and sexual pain the heritability at follow-up was higher compared to baseline (28% vs 34% and 30% vs 45%, respectively). The heritability of lubrication remained stable at 27%. According to the best-fitting additive environmental (AE) Cholesky model for all domains except for sexual pain there were no new genetic factors expressing themselves over the 4-year period, but an addition of new, unique environmental determinants could be observed. For sexual pain an additional genetic factor could be observed at follow-up, explaining 39% of the phenotypic variance. CLINICAL TRANSLATION: The biological pre-disposition to sexual problems seems to remain relatively stable over time. CONCLUSIONS: This is the first study to investigate the genetic stability of female sexual functioning in a large population sample of women. White ethnicity and the relatively high mean age of women asks for caution in extrapolating the findings to other ethnic and age groups. The findings highlight the value of more in-depth exploration of the non-shared environmental influences that could provide clues to the mechanisms behind remittance and/or persistence of sexual problems. Integration of these findings may provide a useful conceptual framework for the treatment and prevention of certain types of sexual problems. Burri A, Ogata S. Stability of Genetic and Environmental Influences on Female Sexual Functioning. J Sex Med 2018;XX:XXX-XXX.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180310
[Lr] Last revision date:180310
[St] Status:Publisher

  6 / 39639 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29473197
[Au] Autor:Kang JH; Sung J; Song YM; Kim YH
[Ad] Address:Clinic of Oral Medicine and Orofacial Pain, Institute of Oral Health Science, Ajou University School of Medicine, Suwon, Korea.
[Ti] Title:Heritability of the airway structure and head posture using twin study.
[So] Source:J Oral Rehabil;, 2018 Feb 23.
[Is] ISSN:1365-2842
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Inherited traits of obstructive sleep apnoea (OSA) may have link to the heritability of the airway anatomy. The aim of this study was to investigate heritability of the airway anatomy by comparing skeletal and soft tissue features of Korean monozygotic twins (MZ) and dizygotic twins (DZ). In total, 72 participants (mean age, 41.5 ± 5.9 years; 40 males, 32 females) including 48 MZ (24 pairs) and 24 DZ (12 pairs) with same sex were participated. The craniofacial, craniovertebral, hyoideal and pharyngeal parameters were measured using lateral cephalograms. The genetic analysis was performed using Falconer's method. High heritability was detected in the hyoid position and inclination of the cervical column. The velopharyngeal and hypopharyngeal dimensions showed higher heritability compared to those of the nasopharynx and oropharynx. The body mass index (BMI) had interactions with the nasopharyngeal and hypopharyngeal dimensions and length of the tongue and soft palate. The mandibular growth had correlations with the nasopharyngeal and hypopharyngeal dimensions. The vertical skeletal relationships appeared to have interaction with the nasopharyngeal, velopharyngeal and hypopharyngeal dimensions, as well as length of the tongue and soft palate. A forwarded inclination of the cervical columns was seen in connections with BMI and the nasopharyngeal and hypopharyngeal dimensions. The airway structures and head postures seemed to be under strong genetic controls. The airway dimensions had associations with BMI, head postures and skeletal structures which showed high heritability. Forwarded head postures would be physiological adaptations of compromised airway adequacy by increased BMI and retrognathia.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180310
[Lr] Last revision date:180310
[St] Status:Publisher
[do] DOI:10.1111/joor.12620

  7 / 39639 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29410205
[Au] Autor:Hallgrímsson HT; Cieslak M; Foschini L; Grafton ST; Singh AK
[Ad] Address:Department of Computer Science, University of California, Santa Barbara, CA 93106, USA. Electronic address: hth@cs.ucsb.edu.
[Ti] Title:Spatial coherence of oriented white matter microstructure: Applications to white matter regions associated with genetic similarity.
[So] Source:Neuroimage;172:390-403, 2018 Feb 02.
[Is] ISSN:1095-9572
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:We present a method to discover differences between populations with respect to the spatial coherence of their oriented white matter microstructure in arbitrarily shaped white matter regions. This method is applied to diffusion MRI scans of a subset of the Human Connectome Project dataset: 57 pairs of monozygotic and 52 pairs of dizygotic twins. After controlling for morphological similarity between twins, we identify 3.7% of all white matter as being associated with genetic similarity (35.1 k voxels, p<10 , false discovery rate 1.5%), 75% of which spatially clusters into twenty-two contiguous white matter regions. Furthermore, we show that the orientation similarity within these regions generalizes to a subset of 47 pairs of non-twin siblings, and show that these siblings are on average as similar as dizygotic twins. The regions are located in deep white matter including the superior longitudinal fasciculus, the optic radiations, the middle cerebellar peduncle, the corticospinal tract, and within the anterior temporal lobe, as well as the cerebellum, brain stem, and amygdalae. These results extend previous work using undirected fractional anisotrophy for measuring putative heritable influences in white matter. Our multidirectional extension better accounts for crossing fiber connections within voxels. This bottom up approach has at its basis a novel measurement of coherence within neighboring voxel dyads between subjects, and avoids some of the fundamental ambiguities encountered with tractographic approaches to white matter analysis that estimate global connectivity.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher

  8 / 39639 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29521179
[Au] Autor:Koethe D; Pahlisch F; Hellmich M; Rohleder C; Mueller JK; Meyer-Lindenberg A; Torrey EF; Piomelli D; Leweke FM
[Ad] Address:a Brain and Mind Centre, University of Sydney , Sydney , Australia.
[Ti] Title:Familial Abnormalities of Endocannabinoid Signaling in Schizophrenia.
[So] Source:World J Biol Psychiatry;:1-26, 2018 Mar 09.
[Is] ISSN:1814-1412
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:OBJECTIVES: Epidemiological and experimental evidence suggests that the endocannabinoid system plays a pathophysiologic role in schizophrenia. This is reflected by elevated cerebrospinal levels of the endocannabinoid anandamide in schizophrenia and its initial prodromal states. METHODS: We analyzed plasma concentrations of anandamide, 2-arachidonoyl-sn-glycerol, palmitoylethanolamide and oleoylethanolamide from 25 twin-pairs discordant for schizophrenia, 6 discordant for bipolar disorder and 8 healthy twin-pairs to determine hereditary traits. RESULTS: Twin-pairs discordant for schizophrenia or bipolar disorder had significantly higher levels of anandamide and palmitoylethanolamide compared to healthy twins (both p < 0.002). Non-affected twins discordant for schizophrenia, who developed a psychotic disorder within 5 years follow-up showed lower anandamide (p = 0.042) and 2-arachidonoyl-sn-glycerol levels (p = 0.049) than twins who remained healthy. CONCLUSIONS: We suggest that the protective upregulation of endocannabinoid signalling reflects either a hereditary trait or mirrors a modulating response to genetically influenced cerebral function involving e.g. other neurotransmitters or energy metabolism.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1080/15622975.2018.1449966

  9 / 39639 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29520735
[Au] Autor:Shah JS; Nasab SH; Chappell N; Chen HY; Schutt A; Mendez-Figueroa H
[Ad] Address:Department of Obstetrics & Gynecology, McGovern Medical School at the University of Texas Health Science Center, 6431 Fannin St, Suite 3.214, Houston, TX, 77030, USA. Jaimin.Shah@uth.tmc.edu.
[Ti] Title:Neonatal outcomes among twins stratified by method of conception: secondary analysis of maternal fetal medicine (MFMU) network database.
[So] Source:J Assist Reprod Genet;, 2018 Mar 09.
[Is] ISSN:1573-7330
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:PURPOSE: To investigate whether twin pregnancies conceived by different forms of fertility treatments are associated with adverse neonatal outcomes and to examine the difference in maternal and obstetrical characteristics between patients. METHODS: Our study was a retrospective analysis of twin pregnancies conceived by fertility treatments from a prospectively collected database. Treatments were stratified into two groups: group 1 (ART) consisted of in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI), and group 2 (non-ART) included intrauterine insemination (IUI) and ovulation induction (OI). Composite neonatal morbidity included respiratory distress syndrome, intraventricular hemorrhage, leukomalacia, chronic lung disease, and death prior to discharge. RESULTS: There were 460 neonates in our study; among them, 67% (n = 310) were in group 1, and 33% (n = 150) in group 2. Group 1 patients were more likely to be older (p = 0.004), nulliparous (p = 0.01), delivered twins with lower birth weights (2278 g ± 605 vs. 2427 ± 519, p = 0.009), and had more deliveries < 32 weeks gestation (p = 0.001). In multivariable Poisson regression model, only neonatal intensive care unit admission rate was increased for group 1 twins (aRR = 1.27, 95% CI 1.003-1.60). CONCLUSIONS: After adjusting for confounders, twins conceived via ART compared to non-ART had similar neonatal outcomes. These data can help when counseling this patient population and assist in planning larger prospective cohorts.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1007/s10815-018-1149-x

  10 / 39639 MEDLINE  
              first record previous record
select
to print
Photocopy
Full text

[PMID]: 29518222
[Au] Autor:Li S; Wong EM; Dugué PA; McRae AF; Kim E; Joo JE; Nguyen TL; Stone J; Dite GS; Armstrong NJ; Mather KA; Thalamuthu A; Wright MJ; Ames D; Milne RL; Craig JM; Saffery R; Montgomery GW; Song YM; Sung J; Spector TD; Sachdev PS; Giles GG; Southey MC; Hopper JL
[Ad] Address:Centre for Epidemiology and Biostatistics.
[Ti] Title:Genome-wide average DNA methylation is determined in utero.
[So] Source:Int J Epidemiol;, 2018 Mar 06.
[Is] ISSN:1464-3685
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Background: Investigating the genetic and environmental causes of variation in genome-wide average DNA methylation (GWAM), a global methylation measure from the HumanMethylation450 array, might give a better understanding of genetic and environmental influences on methylation. Methods: We measured GWAM for 2299 individuals aged 0 to 90 years from seven twin and/or family studies. We estimated familial correlations, modelled correlations with cohabitation history and fitted variance components models for GWAM. Results: The correlation in GWAM for twin pairs was ∼0.8 at birth, decreased with age during adolescence and was constant at ∼0.4 throughout adulthood, with no evidence that twin pair correlations differed by zygosity. Non-twin first-degree relatives were correlated, from 0.17 [95% confidence interval (CI): 0.05-0.30] to 0.28 (95% CI: 0.08-0.48), except for middle-aged siblings (0.01, 95% CI: -0.10-0.12), and the correlation increased with time living together and decreased with time living apart. Spouse pairs were correlated in all studies, from 0.23 (95% CI: 0.3-0.43) to 0.31 (95% CI: 0.05-0.52), and the correlation increased with time living together. The variance explained by environmental factors shared by twins alone was 90% (95% CI: 74-95%) at birth, decreased in early life and plateaued at 28% (95% CI: 17-39%) in middle age and beyond. There was a cohabitation-related environmental component of variance. Conclusions: GWAM is determined in utero by prenatal environmental factors, the effects of which persist throughout life. The variation of GWAM is also influenced by environmental factors shared by family members, as well as by individual-specific environmental factors.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:Publisher
[do] DOI:10.1093/ije/dyy028


page 1 of 3964 go to page                         
   


Refine the search
  Database : MEDLINE Advanced form   

    Search in field  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/PAHO/WHO - Latin American and Caribbean Center on Health Sciences Information