Database : MEDLINE
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[PMID]: 29524814
[Au] Autor:Liu X; Lv Y; Xu K; Xiao X; Xi B; Lu S
[Ad] Address:School of Environment, Tsinghua University, Beijing 100084, People's Republic of China; State Environmental Protection Scientific Observation and Research Station for Lake Dongtinghu (SEPSORSLD), National Engineering Laboratory for LakePollution Control and Ecological Restoration, Chinese Research A
[Ti] Title:Response of ginger growth to a tetracycline-contaminated environment and residues of antibiotic and antibiotic resistance genes.
[So] Source:Chemosphere;201:137-143, 2018 Mar 01.
[Is] ISSN:1879-1298
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:The presence of antibiotic residues in vegetables has been highlighted as a risk to human health; antibiotics not only cause toxic effects to plants but can also induce antibiotic resistance gene (ARG) expression. Using a soil-free approach, this study aimed to explore the response of ginger growth to tetracycline (TC) pollution and to assess the levels of antibiotic residues in different plant organs and the presence of ARGs in the rhizome. Ginger growth in a highly TC-contaminated environment was remarkably inhibited. Photosynthetic parameters, fluorescence parameters, and some physiological indicators (oxidative substances, photosynthetic pigments, enzyme activity, etc.) were negatively influenced by TC contamination. Although the superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT) activity levels significantly increased, their effects appear to be limited. The accumulation of TC in the rhizome (28.1 mg kg ) was greater than that in the roots, stem, or leaves. All tested antibiotic resistance genes except for tetL were detectable in the rhizome, and their relative abundance was in the order integron1>tetG > tetA > tetC > tetB > tetM. The level of TC in ginger rhizomes was much higher than the maximum residue limits. The potential dose of TC acquired from the consumption of ginger grown in a highly TC-contaminated environment poses no obvious risk to adults but may be a threat to children.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180310
[Lr] Last revision date:180310
[St] Status:Publisher

  2 / 37911 MEDLINE  
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[PMID]: 29524810
[Au] Autor:Yuan S; Yu HJ; Liu MW; Huang Y; Yang XH; Tang BW; Song Y; Cao ZK; Wu HJ; He QQ; Gasevic D
[Ad] Address:School of Health Sciences, Wuhan University, PR China.
[Ti] Title:The association of fruit and vegetable consumption with changes in weight and body mass index in Chinese adults: a cohort study.
[So] Source:Public Health;157:121-126, 2018 Mar 07.
[Is] ISSN:1476-5616
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:OBJECTIVES: Findings regarding the benefits of fruit and vegetables (FV) on weight control are inconsistent and little is known among Chinese populations. Therefore, we examined the relationship between change in FV consumption, weight, and change in body mass index (BMI) among Chinese adults, participants of the China Health and Nutrition Survey (CHNS). STUDY DESIGN: A prospective cohort study. METHODS: Two waves of CHNS conducted in 2006 and 2011 were used. Continuous FV consumption increase was considered as the exposure and changes in weight and BMI as outcomes. Change in FV consumption was categorized into quintiles. Analysis of covariance and multiple linear regression models, after controlling for potential confounders such as energy intake, physical activity, and smoking, were used to describe the relationship between change in FV consumption and change in weight and BMI. RESULTS: A total of 4357 participants aged 18-65 years were included in this study. The respective weight and BMI gains in male individuals were 1.81kg and 0.73kg/m in the fifth quintile of FV change relative to individuals in the first quintile (3.67kg for weight gain and 1.48kg/m for BMI gain). An increase in FV consumption by 100g was associated with a 211g weight loss (B=-2.11; 95% confidence interval [CI], -3.34, -0.89, P<0.001) and a decrease in BMI by 0.94kg/m (B=-0.94; 95% CI, -1.36, -0.46, P<0.001) in men; and a 140g weight loss (B=-0.14; 95% CI, -0.97, 0.69, P=0.74) and a decrease in BMI by 0.29kg/m BMI (B=-0.29; 95% CI, -0.63, 0.06, P=0.11) in women. CONCLUSIONS: Increase in FV consumption was associated with statistically significant weight loss and decrease in BMI among Chinese men, and, although suggested, weight loss among women was not significant. Considering the protective effect of FV on human health, increasing FV consumption in the Chinese population is recommended.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180310
[Lr] Last revision date:180310
[St] Status:Publisher

  3 / 37911 MEDLINE  
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[PMID]: 29524792
[Au] Autor:Griffith R; von Hinke S; Smith S
[Ad] Address:Institute for Fiscal Studies and University of Manchester, United Kingdom. Electronic address: rgriffith@ifs.org.uk.
[Ti] Title:Getting a healthy start: The effectiveness of targeted benefits for improving dietary choices.
[So] Source:J Health Econ;58:176-187, 2018 Feb 24.
[Is] ISSN:1879-1646
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:There is growing policy interest in encouraging better dietary choices. We study a nationally-implemented policy - the UK Healthy Start scheme - that introduced vouchers for fruit, vegetables and milk. We show that the policy has increased spending on fruit and vegetables and has been more effective than an equivalent-value cash benefit. We also show that the policy improved the nutrient composition of households' shopping baskets, with no offsetting changes in spending on other foodstuffs.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180310
[Lr] Last revision date:180310
[St] Status:Publisher

  4 / 37911 MEDLINE  
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[PMID]: 29524780
[Au] Autor:Fernandes C; Figueira E; Tauler R; Bedia C
[Ad] Address:Departamento de Biologia & CESAM, Universidade de Aveiro, Campus Universitrio de Santiago, 3810-193 Aveiro, Portugal.
[Ti] Title:Exposure to chlorpyrifos induces morphometric, biochemical and lipidomic alterations in green beans (Phaseolus vulgaris).
[So] Source:Ecotoxicol Environ Saf;156:25-33, 2018 Mar 07.
[Is] ISSN:1090-2414
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:Chlorpyrifos (CPF) is a worldwide used pesticide that raises concerns from the environmental and human health perspectives. The presence of pesticides such as CPF in edible vegetables has been already reported, but little is known about the effects induced by this pesticide stress on the morphology, oxidative response and lipid composition of treated plants. In this work, green bean plants (Phaseolus vulgaris) were exposed to increasing concentrations of CPF and the different plant parts (roots, stem bases, stem, leaves, pods and beans) were subjected to different analyses. First, morphometric parameters and the oxidative response caused by CPF were explored. In a second phase of the study, an untargeted lipidomic analysis of the different tissue extracts was performed and MALDI-TOF mass spectrometry images of pods and beans were recorded and analysed to illustrate the spatial distribution of the changes observed. As a result of CPF treatment, plants showed a significant decrease in their height, leaf length, and pod number. The biochemical analysis showed lipid peroxidation and the activation of antioxidant mechanisms in roots, stem and leaves. Regarding the lipidomic results, changes in lipid levels were observed, mainly in leaves, pods and seeds. The main changes observed were a reduction of photosynthetic pigments and lipids in leaves and a decrease of triacylglycerols levels in pods and seeds. This last point was confirmed by the analysis of mass spectrometry images of the pods. These observations suggest that CPF would affect the yield of green bean crops as well as the nutritional value of pods and beans. This work represents a step forward in the knowledge of the effects of CPF, one of the most used pesticides worldwide, in plants.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180310
[Lr] Last revision date:180310
[St] Status:Publisher

  5 / 37911 MEDLINE  
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[PMID]: 29510368
[Au] Autor:Li Y; Long L; Yan H; Ge J; Cheng J; Ren L; Yu X
[Ad] Address:Jiangsu Key Laboratory for Food Quality and Safety-State Key Laboratory Cultivation Base of Ministry of Science and Technology, 50 Zhongling Street, Nanjing 210014, China; Institute of Food Quality and Safety, Jiangsu Academy of Agricultural Sciences, 50 Zhongling Street, Nanjing 210014, China.
[Ti] Title:Comparison of uptake, translocation and accumulation of several neonicotinoids in komatsuna (Brassica rapa var. perviridis) from contaminated soils.
[So] Source:Chemosphere;200:603-611, 2018 Feb 20.
[Is] ISSN:1879-1298
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:The accumulation of pesticides in vegetables may have serious effects on human health and ecosystems via food chains; therefore, it is of great importance to investigate the uptake and accumulation behaviours of pesticides in vegetable tissues. In the present study, the uptake, translocation and accumulation of five neonicotinoids, thiamethoxam (THIM), clothianidin (CLO), thiacloprid (THID), acetamiprid (ACE) and dinotefuran (DIN), in komatsuna (Brassica rapa var. perviridis, a vegetable) were investigated. The concentrations of neonicotinoids in vegetable tissues ranged from 0.068  0.002 to 29.6  2.5 mg/kg. During the cultivation (except for the first day), the concentration of each neonicotinoid in shoots was the highest, followed by roots and the soil. The concentrating of neonicotinoids from the soil to roots followed the order of THIM > CLO > THID > DIN > ACE, while the order of the ability of translocation neonicotinoids from roots to shoots was the just opposite. The difference in uptake and translocation behaviours of the test neonicotinoids seems to be not correlated with the octanol/water partition coefficient (logK ), water solubility or dissociation constant (pK ), but significantly correlated with molecular weight. In addition, a greater concentration of the THIM-metabolite clothianidin (M-CLO) was detected in vegetable shoots than in roots and the soil.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180310
[Lr] Last revision date:180310
[St] Status:Publisher

  6 / 37911 MEDLINE  
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[PMID]: 29427693
[Au] Autor:Myers G; Wright S; Blane S; Pratt IS; Pettigrew S
[Ad] Address:Cancer Council Western Australia, 420 Bagot Road, Subiaco WA 6180, Australia; School of Psychology, Curtin University, GPO Box U1987, Perth WA 6845, Australia. Electronic address: gael.myers@curtin.edu.au.
[Ti] Title:A process and outcome evaluation of an in-class vegetable promotion program.
[So] Source:Appetite;125:182-189, 2018 Feb 07.
[Is] ISSN:1095-8304
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:OBJECTIVE: Nutrition interventions that target both fruits and vegetables are effective in increasing fruit consumption, but have been limited in their ability to improve vegetable intake. To address the low proportion of children meeting vegetable intake guidelines, approaches specifically targeting vegetables are needed. This paper reports on a mixed-method analysis of a 10-week vegetable promotion pilot project that aimed to increase vegetable intake as part of the existing Crunch&Sip in-class fruit and vegetable break program. DESIGN: The intervention was designed to promote vegetable consumption through the implementation of vegetable-focused resources, including curriculum resources and parent education materials. Teachers completed pre- and end-of-intervention surveys. Process measures related to the use of resources and teachers' perceptions of barriers to implementation. The outcome evaluation included measures of children's vegetable consumption during Crunch&Sip breaks and teachers' attitudes and confidence relating to educating students about the benefits of consuming vegetables. SUBJECTS: Twenty-one Western Australian primary schools already participating in the Crunch&Sip program participated in the pilot intervention and evaluation. Coverage included 35 primary school teachers representing 818 students aged 4-11 years. RESULTS: The proportion of children bringing vegetables for Crunch&Sip more than doubled over the 10-week intervention (21% vs 46%; p < 0.001). Improvements were observed in teachers' perceived knowledge about the nutritional benefits of vegetables (p = 0.001) and confidence to educate students about the benefits of vegetable consumption (p = 0.028). CONCLUSIONS: Preferentially promoting vegetable consumption as part of an existing school-based nutrition program may be an effective strategy to increase children's vegetable intake.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180310
[Lr] Last revision date:180310
[St] Status:Publisher

  7 / 37911 MEDLINE  
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[PMID]: 29408332
[Au] Autor:Rohde JF; Bohman B; Berglind D; Hansson LM; Frederiksen P; Mortensen EL; Heitmann BL; Rasmussen F
[Ad] Address:Research Unit for Dietary Studies at the Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Nordre Fasanvej 57, Street 8, Entrance 11, 2000 Frederiksberg, Denmark; Department of Research and Development, Health Science, University College UCC, Carlsbergvej 14, 3400 Hillerd, Denmar
[Ti] Title:Cross-sectional associations between maternal self-efficacy and dietary intake and physical activity in four-year-old children of first-time Swedish mothers.
[So] Source:Appetite;125:131-138, 2018 Feb 03.
[Is] ISSN:1095-8304
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Healthy dietary and physical activity behaviours are established early in life where children learn by observing their parents. Therefore, parents can act as role models and influence their children toward a healthier lifestyle. Besides a strong association between parental and child health behaviours, parents also influence their children's health behaviours through socio-cognitive processes, where perceived self-efficacy is the central component. The objective was to examine if parental self-efficacy among Swedish mothers was associated with their four-year-old children's dietary and physical activity behaviours. METHODS: This cross-sectional study was based on information from control participants that took part in the Swedish primary prevention trial of childhood obesity (PRIMROSE) (n = 420 mother-child pairs). Linear regression models were used to examine the associations between parental self-efficacy (Parental Self-Efficacy for Promoting Healthy Physical Activity and Dietary Behaviours in Children Scale) and children's dietary intake (parent reported) and levels of physical activity (accelerometer) with adjustments for potential confounders. RESULTS: Mothers' efficacy beliefs in promoting healthy dietary or physical activity behaviours in their children were associated with a slightly higher consumption of fruit and vegetables among their children (: 0.03 [95%CI: 0.01; 0.04] P < 0.001) and slightly higher levels of moderate-to-vigorous activity (: 0.43 [95%CI: 0.05; 0.81] P = 0.03). Mothers' belief in their ability to limit unhealthy dietary and physical activity behaviours was inversely associated with children's intake of unhealthy snacks (:-0.06 [95%CI:-0.10;-0.02] P < 0.01). CONCLUSION: Our cross-sectional study suggests weak positive correlations between maternal self-efficacy and healthy dietary and physical activity behaviours, and weak inverse associations between maternal self-efficacy and unhealthy dietary and physical activity behaviours among their children.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180310
[Lr] Last revision date:180310
[St] Status:Publisher

  8 / 37911 MEDLINE  
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[PMID]: 29523939
[Au] Autor:Socas-Rodrguez B; Gonzlez-Slamo J; Herrera-Herrera AV; Santana-Mayor ; Hernndez-Borges J
[Ad] Address:Servicio General de Apoyo a la Investigacin (SEGAI), Universidad de La Laguna (ULL), Avda. Astrofsico Fco. Snchez s/n, 38206, San Cristbal de La Laguna, Spain.
[Ti] Title:Determination of phthalic acid esters in different baby food samples by gas chromatography tandem mass spectrometry.
[So] Source:Anal Bioanal Chem;, 2018 Mar 09.
[Is] ISSN:1618-2650
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:In this work, a new method has been developed for the determination of 14 phthalic acid esters (i.e., benzylbutyl phthalate (BBP), bis-2-n-butoxyethyl phthalate (DBEP), dibutyl phthalate (DBP), dicyclohexyl phthalate (DCHP), bis-2-ethoxyethyl phthalate (DEEP), diethyl phthalate (DEP), diisodecyl phthalate (DIDP), diisononyl phthalate (DINP), bis-isopentyl phthalate (DIPP), bis (2-methoxyethyl) phthalate (DMEP), dimethyl phthalate (DMP), di-n-octyl phthalate (DNOP), bis-n-pentyl phthalate (DNPP), dipropyl phthalate (DPP)) and one adipate (bis (2-ethylhexyl) adipate (DEHA)) in different baby foods. Separation was carried out by gas chromatography triple quadrupole tandem mass spectrometry while the previous extraction of the samples was carried out using the QuEChERS method. The methodology was validated for four baby food samples (two fruit compotes of different compositions and two meat and fish purees with vegetables) using dibutyl phthalate-3,4,5,6-d (DBP-d ) as internal standard. Determination coefficients (R ) of matrix-matched calibration curves were above 0.9922 in all cases while relative recovery values ranged between 70 and 120%, with relative standard deviation values below 19%. The limits of quantification of the method ranged between 0.03 and 1.11g/kg. Finally, the analysis of commercially available samples was carried out finding the presence of BBP, DEHA, DEP, DIDP, and DPP in some of the studied samples.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180310
[Lr] Last revision date:180310
[St] Status:Publisher
[do] DOI:10.1007/s00216-018-0977-y

  9 / 37911 MEDLINE  
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[PMID]: 29174923
[Au] Autor:Mnzel T; Daiber A
[Ad] Address:Center for Cardiology, Cardiology 1, Medical Center of the Johannes Gutenberg University, Mainz, Germany; Center for Thrombosis and Hemostasis (CTH), Medical Center of the Johannes Gutenberg University, Mainz, Germany; Partner Site Rhine-Main, German Center for Cardiovascular Research (DZHK), Mainz, Germany. Electronic address: tmuenzel@uni-mainz.de.
[Ti] Title:Inorganic nitrite and nitrate in cardiovascular therapy: A better alternative to organic nitrates as nitric oxide donors?
[So] Source:Vascul Pharmacol;102:1-10, 2018 Mar.
[Is] ISSN:1879-3649
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:In 1867 the organic nitrite, amyl nitrite, was introduced as a therapeutic agent in the treatment of angina pectoris and was later substituted by the organic nitrate nitroglycerin (NTG). Despite having a highly potent vasodilator capacity in veins>coronary arteries>arterioles, the vasodilator effects NTG are rapidly attenuated by the development of nitrate tolerance. We and others established that NTG treatment stimulates the production of reactive oxygen species such as superoxide and peroxynitrite with subsequent marked attenuation of the NTG vasodilator potency. The nitrite anion (NO ) has more recently been characterized to possess novel pharmacotherapeutic actions such as modulation of vasodilation under hypoxic conditions, thereby providing protection in ischemia-reperfusion injury. Administration of NO /NO has also been shown to improve myocardial function in heart failure and to lower blood pressure. Despite these positive aspects there is still a great need to study inorganic nitrate and nitrite therapy in various cardiovascular diseases in prospective outcome directed studies. In case being successful, this kind of therapy would indeed represent a cheap, therefore affordable, effective cardiovascular therapy without major side effects as observed in response to therapy with organic nitrates.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1711
[Cu] Class update date: 180310
[Lr] Last revision date:180310
[St] Status:In-Data-Review

  10 / 37911 MEDLINE  
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[PMID]: 29051067
[Au] Autor:Wang Y; Ryu BH; Yoo W; Lee CW; Kim KK; Lee JH; Kim TD
[Ad] Address:Department of Chemistry, College of Natural Science, Sookmyung Women's University, Seoul 04310, Republic of Korea.
[Ti] Title:Identification, characterization, immobilization, and mutational analysis of a novel acetylesterase with industrial potential (LaAcE) from Lactobacillus acidophilus.
[So] Source:Biochim Biophys Acta;1862(1):197-210, 2018 01.
[Is] ISSN:0006-3002
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:Lactic acid bacteria, which are involved in the fermentation of vegetables, meats, and dairy products, are widely used for the productions of small organic molecules and bioactive peptides. Here, a novel acetylesterase (LaAcE) from Lactobacillus acidophilus NCFM was identified, functionally characterized, immobilized, and subjected to site-directed mutagenesis for biotechnological applications. The enzymatic properties of LaAcE were investigated using biochemical and biophysical methods including native polyacrylamide gel electrophoresis, acetic acid release, biochemical assays, enzyme kinetics, and spectroscopic methods. Interestingly, LaAcE exhibited the ability to act on a broad range of substrates including glucose pentaacetate, glyceryl tributyrate, fish oil, and fermentation-related compounds. Furthermore, immobilization of LaAcE showed good recycling ability and high thermal stability compared with free LaAcE. A structural model of LaAcE was used to guide mutational analysis of hydrophobic substrate-binding region, which was composed of Leu , Phe , and Val . Five mutants (L156A, F164A, V204A, L156A/F164A, and L156A/V204A) were generated and investigated to elucidate the roles of these hydrophobic residues in substrate specificity. This work provided valuable insights into the properties of LaAcE, and demonstrated that LaAcE could be used as a model enzyme of acetylesterase in lactic acid bacteria, making LaAcE a great candidate for industrial applications.
[Mh] MeSH terms primary: Acetylesterase
Bacterial Proteins
Enzymes, Immobilized
Lactobacillus acidophilus
Models, Molecular
Mutation, Missense
[Mh] MeSH terms secundary: Acetylesterase/chemistry
Acetylesterase/genetics
Amino Acid Substitution
Bacterial Proteins/chemistry
Bacterial Proteins/genetics
Enzymes, Immobilized/chemistry
Enzymes, Immobilized/genetics
Lactobacillus acidophilus/enzymology
Lactobacillus acidophilus/genetics
Substrate Specificity/genetics
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Name of substance:0 (Bacterial Proteins); 0 (Enzymes, Immobilized); EC 3.1.1.6 (Acetylesterase)
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[Js] Journal subset:IM
[Da] Date of entry for processing:171021
[St] Status:MEDLINE


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