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[PMID]: 28455319 [Au] Autor: Seiler A; Deichmann R; Nöth U; Pfeilschifter W; Berkefeld J; Singer OC; Klein JC; Wagner M [Ad] Endereço: From the Department of Neurology (A.S., W.P., O.C.S.), Brain Imaging Center and Institute of Neuroradiology (R.D., U.N.), and Institute of Neuroradiology (J.B., M.W.), Goethe University Frankfurt, Germany; Nuffield Department of Clinical Neurosciences, Oxford University, United Kingdom (J.C.K.); and [Ti] Título: Oxygenation-Sensitive Magnetic Resonance Imaging in Acute Ischemic Stroke Using T2'/R2' Mapping: Influence of Relative Cerebral Blood Volume. [So] Source: Stroke;48(6):1671-1674, 2017 06. [Is] ISSN: 1524-4628 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: BACKGROUND AND PURPOSE: Quantitative T2'/R2' mapping detect locally increased concentrations of deoxygenated hemoglobin-causing a decrease of T2' and increase of R2'-and might reflect increased cerebral oxygen extraction fraction. Because increases of (relative) cerebral blood volume (rCBV) may influence T2' and R2' through accumulation of deoxygenated hemoglobin, we aimed to investigate the impact of rCBV on T2'/R2' in patients with ischemic stroke. METHODS: Data from patients with acute internal carotid artery and middle cerebral artery occlusion were analyzed. T2', R2', and rCBV were measured within the ischemic core, slightly and severely hypoperfused areas, and their relationship was examined. RESULTS: A strong negative correlation with rCBV was found for R2' ( =-0.544; =0.002), and T2' correlated positively with rCBV ( =0.546; =0.001) in time-to-peak-delayed areas. T2'/R2' within hypoperfused tissue remained unchanged at normal or elevated rCBV levels. CONCLUSIONS: T2' decrease/R2' increase within hypoperfused areas in ischemic stroke is not caused by local elevations of rCBV but most probably only by increased cerebral oxygen extraction fraction. However, considering rCBV is crucial to assess extent of oxygen extraction fraction changes by means of T2'/R2'. [Mh] Termos MeSH primário: Isquemia Encefálica/diagnóstico por imagem Volume Sanguíneo Cerebral/fisiologia Imagem por Ressonância Magnética/métodos Oxigênio/metabolismo Acidente Vascular Cerebral/diagnóstico por imagem [Mh] Termos MeSH secundário: Idoso Idoso de 80 Anos ou mais Arteriopatias Oclusivas/diagnóstico por imagem Doenças das Artérias Carótidas/diagnóstico por imagem Feminino Seres Humanos Infarto da Artéria Cerebral Média/diagnóstico por imagem Masculino Meia-Idade [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: S88TT14065 (Oxygen) [Em] Mês de entrada: 1707 [Cu] Atualização por classe: 180305 [Lr] Data última revisão: 180305 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170430 [St] Status: MEDLINE [do] DOI: 10.1161/STROKEAHA.117.017086

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[PMID]: 29390277 [Au] Autor: Fan L; Ma W; Zhang H; Cai J [Ad] Endereço: State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. [Ti] Título: A rare case report of bilateral common and internal iliac arterial fibromuscular dysplasia: Coexisted dissection, aneurysm, and stenosis. [So] Source: Medicine (Baltimore);96(50):e8896, 2017 Dec. [Is] ISSN: 1536-5964 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: RATIONALE: Iliac arterial fibromuscular dysplasia (FMD) was rarely reported and its demographic, clinical, and imaging features have not been precisely described resulting in uncertain therapeutic methods. PATIENT CONCERNS: A 31-year-old man was referred because of 3-month-ago onset hypertension, low serum potassium, and a small-sized right kidney with normal renal artery under ultrasound examination. This patient was suspected of primary aldosteronism, whereas spirolactone was poorly effective. DIAGNOSIS: Contrast-enhanced computed tomographic angiography (CTA) and three-dimensional reconstruction of the whole aorta discovered an aneurysm from the right common iliac artery (CIA) to the internal iliac artery, consistent with a left CIA dissection and a remarkable right renal artery aneurysm before a stenosis. Iliac and renal arteries FMD were then confirmed through digital subtraction angiography (DSA). INTERVENTION: Percutaneous transluminal angioplasty (PTA) of right renal artery was operated and a stent was deployed in left CIA. OUTCOMES: This patient was normotensive, asymptomatic, and free from recurrence without any antihypertensive agents at an 8-month follow-up. LESSONS: To our knowledge, this is the first bilateral common and internal iliac arterial FMD case in China, with unique asymptomatic dissection, aneurysm, and renovascular hypertension. Screening for secondary hypertension in young population and for iliac or renal arterial FMD is therefore suggested with CTA and reconstruction from neck to pelvis and MRA in those with intracranial disorders. Among youth FMD, the potential of PTRA in renovascular hypertension out of antihypertensive drugs and stent in dissection is novelly indicated. [Mh] Termos MeSH primário: Aneurisma/diagnóstico Arteriopatias Oclusivas/diagnóstico Displasia Fibromuscular/diagnóstico Artéria Ilíaca [Mh] Termos MeSH secundário: Adulto Aneurisma/cirurgia Angiografia Digital China Comorbidade Angiografia por Tomografia Computadorizada Diagnóstico Diferencial Displasia Fibromuscular/cirurgia Seres Humanos Imagem Tridimensional Masculino Stents [Pt] Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180301 [Lr] Data última revisão: 180301 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 180203 [St] Status: MEDLINE [do] DOI: 10.1097/MD.0000000000008896

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[PMID]: 29350897 [Au] Autor: Tomic A; Milovic N; Marjanovic I; Lekovic; Bjelanovic Z; Sarac M; Vavic N; Ignjatovic L; Stamenkovic D; Mickovic S [Ti] Título: Aortobifemoral reconstruction and renal transplantation in a patient with abdominal aortic aneurysm and occlusion of iliac arteries: A case report. [So] Source: Vojnosanit Pregl;74(1):81-4, 2017 Jan. [Is] ISSN: 0042-8450 [Cp] País de publicação: Serbia [La] Idioma: eng [Ab] Resumo: Introduction: Aortoiliac occlusive disease and abdominal aortic aneurysm in patients with renal insufficiency on hemodialysis can significantly influence the success of renal transplantation. In the recent past, advanced atherosclerosis was considered as contraindication for renal transplantation. Complicated creation of vascular anastomoses and progression of occlusive or aneurysmal disease were the main reasons. Case report: We presented a 52-year-old man with a 5-year history of end-stage renal disease on haemodialysis. The patient was previously excluded from renal transplantation program because of severe aortoiliac atherosclerosis and abdominal aortic aneurysm. Resection of abdominal aortic aneurysm with occlusion of the iliac arteries and reconstruction with aortobifemoral synthetic grafts was performed and followed by cadaveric renal transplantation. Conclusion: Advanced atherosclerotic disease in aortoiliac segment requires elective vascular surgical reconstruction, as part of preparation for renal transplantation in patients with end-stage renal disease. [Mh] Termos MeSH primário: Aneurisma da Aorta Abdominal/cirurgia Arteriopatias Oclusivas/cirurgia Implante de Prótese Vascular/métodos Artéria Femoral/cirurgia Artéria Ilíaca/cirurgia Falência Renal Crônica/cirurgia Transplante de Rim [Mh] Termos MeSH secundário: Aneurisma da Aorta Abdominal/complicações Aneurisma da Aorta Abdominal/diagnóstico por imagem Aortografia/métodos Arteriopatias Oclusivas/complicações Arteriopatias Oclusivas/diagnóstico por imagem Prótese Vascular Implante de Prótese Vascular/instrumentação Angiografia por Tomografia Computadorizada Artéria Femoral/diagnóstico por imagem Seres Humanos Artéria Ilíaca/diagnóstico por imagem Falência Renal Crônica/complicações Falência Renal Crônica/diagnóstico Masculino Meia-Idade Polietilenotereftalatos Desenho de Prótese Resultado do Tratamento [Pt] Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE [Nm] Nome de substância: 0 (Polyethylene Terephthalates) [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180213 [Lr] Data última revisão: 180213 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 180120 [St] Status: MEDLINE [do] DOI: 10.2298/VSP140609139T

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[PMID]: 29381979 [Au] Autor: Jud P; Gary T; Hafner F; Tiesenhausen K; Ott T; Oswald WK; Brodmann M [Ad] Endereço: Division of Angiology, Department of Internal Medicine. [Ti] Título: Multiple arterial thromboses due to cystic medial degeneration Erdheim-Gsell: A case report. [So] Source: Medicine (Baltimore);96(47):e8782, 2017 Nov. [Is] ISSN: 1536-5964 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: RATIONALE: Cystic medial degeneration Erdheim-Gsell is a vascular pathology mainly of the large vessels, which is mostly associated with Marfan syndrome or Ehlers-Danlos syndrome. The clinical findings of this entity are aneurysms of the aorta or large peripheral arteries which usually present in an acute setting due to rupture of an aneurysm. PATIENT CONCERNS: We present a case of a 43-year-old Caucasian male with histologically proven cystic medial degeneration of the lower limb vessels mimicking peripheral artery occlusive disease. Despite antiplatelet and anticoagulant treatment, the patient suffered multiple vascular stenosis and occlusions. DIAGNOSES: Multiple arterial stenoses and thromboses leading to peripheral artery occlusive disease caused by cystic medial degeneration Erdheim-Gsell. INTERVENTIONS: Multiple surgical and endovascular interventions including bypass graft and intra-arterial thrombolysis as well as oral antiplatelet and anticoagulant therapy. OUTCOME: Despite dual antiplatelet therapy, anticoagulant therapy with rivaroxaban and multiple surgical and endovascular interventions, the patient developed recurrent arterial thromboses. The patient did not suffer further thrombotic events since clopidogrel and phenprocoumon were administered. LESSONS: Clinical presentation of cystic medial degeneration Erdheim-Gsell mimicking peripheral artery occlusive disease is very unusual. Due to the fragile vessel wall, patients with cystic medial degeneration might have a higher risk to develop arterial thromboses, even under antiplatelet therapy or anticoagulant treatment. [Mh] Termos MeSH primário: Aneurisma da Aorta Torácica/complicações Arteriopatias Oclusivas/etiologia Cistos/complicações Trombose/etiologia [Mh] Termos MeSH secundário: Adulto Seres Humanos Masculino [Pt] Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180208 [Lr] Data última revisão: 180208 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 180201 [St] Status: MEDLINE [do] DOI: 10.1097/MD.0000000000008782

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[PMID]: 29311538 [Au] Autor: Carneiro Júnior FCF; Carrijo ENDA; Araújo ST; Nakano LCU; de Amorim JE; Cacione DG [Ad] Endereço: Service of Vascular and Endovascular Surgery, Federal University of São Paulo, São Paulo, SP, Brazil. [Ti] Título: Popliteal Artery Entrapment Syndrome: A Case Report and Review of the Literature. [So] Source: Am J Case Rep;19:29-34, 2018 Jan 09. [Is] ISSN: 1941-5923 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: BACKGROUND Popliteal artery entrapment syndrome (PAES) results from an anomalous relationship between the popliteal artery and the myofascial structures of the popliteal fossa. The most common presenting symptoms include intermittent pain in the feet and calves on exercise, resulting in lameness. PAES can lead to popliteal artery thrombosis, stenosis, distal arterial thromboembolism, or arterial aneurysm. The treatment of PAES includes surgical exploration with fasciotomy, myotomy, or sectioning of fibrous band formation, to release the popliteal artery. However, in cases with thrombotic occlusion, thromboendarterectomy with venous patch arterioplasty, or venous graft arterial bypass surgery may be required. This report describes the presentation and surgical management of a case of PAES presenting with limb pain and includes a review of the literature on this condition. CASE REPORT A previously healthy 47-year-old woman presented with a 20-day history of sudden pain in the left lower limb, associated with pallor and a loss of arterial pulses below the knee. Angiography of the affected limb showed occlusion of the left supragenicular popliteal artery, with arterial occlusion, suggestive of arterial thrombus. Imaging of the right popliteal artery, which was not occluded, showed that it was medially deviated. An ipsilateral saphenous vein graft was used to bypass the left supragenicular popliteal artery to the infragenicular popliteal artery, resulting in resolution of the patient's symptoms. CONCLUSIONS PAES is rare and can be under-diagnosed, possibly due to lack of knowledge of this condition. However, if the diagnosis is made early, the prognosis is usually favorable, following appropriate surgical treatment. [Mh] Termos MeSH primário: Arteriopatias Oclusivas/cirurgia Artéria Poplítea Veia Safena/transplante Trombose/cirurgia [Mh] Termos MeSH secundário: Angiografia/métodos Arteriopatias Oclusivas/diagnóstico por imagem Arteriopatias Oclusivas/etiologia Feminino Seres Humanos Meia-Idade Artéria Poplítea/diagnóstico por imagem Artéria Poplítea/cirurgia Síndrome Trombose/diagnóstico por imagem Resultado do Tratamento Grau de Desobstrução Vascular [Pt] Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE; REVIEW [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180205 [Lr] Data última revisão: 180205 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 180110 [St] Status: MEDLINE

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[PMID]: 28463782 [Au] Autor: Zhang Q; Wang A; Zhang S; Li N; Chen S; Zhang Y; Zhou Y; Wu S; Zhao X [Ad] Endereço: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, China; Center of Stroke, Beijing Institute for Brain Disorders, China; Beijing Key Laboratory of Translational Medicine for Cerebrovascula [Ti] Título: Asymptomatic polyvascular disease and the risks of cardiovascular events and all-cause death. [So] Source: Atherosclerosis;262:1-7, 2017 Jul. [Is] ISSN: 1879-1484 [Cp] País de publicação: Ireland [La] Idioma: eng [Ab] Resumo: BACKGROUND AND AIMS: Atherosclerosis is a diffuse and systemic disease. We aimed to assess prevalence and outcome of extracoronary polyvascular disease (polyVD) in the asymptomatic Chinese community population. METHODS: A random sample of 5440 participants aged 40 years or older were enrolled in the Asymptomatic Polyvascular Abnormalities Community Study from 2010 to 2011. Intracranial artery stenosis, extracranial artery stenosis, and lower extremity artery disease were detected by transcranial Doppler and duplex sonography, and by calculating the ankle brachial index. The study endpoints included the first occurrence of stroke, myocardial infarction (MI) and all-cause death. RESULTS: PolyVD (two or three affected vascular territories) was found in 3.0% of the participants, and was significantly higher in men (4.3%). Over a median follow-up of 4.1 years, we identified a total of 247 events (4.7%), including 83 strokes (68 ischemic), 45 MIs and 134 all-cause deaths. After adjusting for age, gender and other potential confounders, we found a significant increase in risk of major cardiovascular events as well as all-cause death in participants with polyVD. In multivariate Cox regression analyses, the adjusted hazard ratios (HR) (95% confidence interval, CI) for the composite of stroke, MI and all-cause death for single and poly-vascular disease (compared with 0 vascular disease) increased from 1.58 (1.19-2.12) to 1.95 (1.26-3.03). Similarly, the adjusted HR (95% CI) for all-cause death for single and poly-vascular disease increased from 1.53 (1.03-2.29) to 2.22 (1.27-3.86). CONCLUSIONS: PolyVD significantly increased the risk of major cardiovascular events and all-cause death in the asymptomatic community population. Performing invasive screening tests for polyVD is useful in the high-risk asymptomatic population. [Mh] Termos MeSH primário: Arteriopatias Oclusivas/epidemiologia Doenças Arteriais Intracranianas/epidemiologia Extremidade Inferior/irrigação sanguínea Infarto do Miocárdio/epidemiologia Doença Arterial Periférica/epidemiologia Acidente Vascular Cerebral/epidemiologia [Mh] Termos MeSH secundário: Adulto Idoso Idoso de 80 Anos ou mais Índice Tornozelo-Braço Arteriopatias Oclusivas/diagnóstico por imagem Arteriopatias Oclusivas/mortalidade Doenças Assintomáticas Causas de Morte Distribuição de Qui-Quadrado China/epidemiologia Progressão da Doença Feminino Seres Humanos Doenças Arteriais Intracranianas/diagnóstico por imagem Doenças Arteriais Intracranianas/mortalidade Estimativa de Kaplan-Meier Masculino Meia-Idade Análise Multivariada Infarto do Miocárdio/diagnóstico Infarto do Miocárdio/mortalidade Doença Arterial Periférica/diagnóstico Doença Arterial Periférica/mortalidade Valor Preditivo dos Testes Prognóstico Modelos de Riscos Proporcionais Estudos Prospectivos Fatores de Risco Acidente Vascular Cerebral/diagnóstico Acidente Vascular Cerebral/mortalidade Fatores de Tempo Ultrassonografia Doppler Dupla Ultrassonografia Doppler Transcraniana [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1801 [Cu] Atualização por classe: 180129 [Lr] Data última revisão: 180129 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170503 [St] Status: MEDLINE

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[PMID]: 28471104 [Au] Autor: Moon BG; Kim JG [Ad] Endereço: Retina Center, Department of Ophthalmology, HanGil Eye Hospital, Incheon, Korea. [Ti] Título: A Case of Ophthalmic Artery Occlusion Following Subcutaneous Injection of Epinephrine Mixed with Lidocaine into the Supratrochlear Area. [So] Source: Korean J Ophthalmol;31(3):277-279, 2017 06. [Is] ISSN: 2092-9382 [Cp] País de publicação: Korea (South) [La] Idioma: eng [Mh] Termos MeSH primário: Arteriopatias Oclusivas/induzido quimicamente Epinefrina/efeitos adversos Lidocaína/efeitos adversos Artéria Oftálmica [Mh] Termos MeSH secundário: Anestésicos Locais/administração & dosagem Anestésicos Locais/efeitos adversos Arteriopatias Oclusivas/diagnóstico Combinação de Medicamentos Epinefrina/administração & dosagem Feminino Seres Humanos Injeções Subcutâneas/efeitos adversos Lidocaína/administração & dosagem Meia-Idade Ritidoplastia/efeitos adversos Tomografia de Coerência Óptica Vasoconstritores/administração & dosagem Vasoconstritores/efeitos adversos [Pt] Tipo de publicação: CASE REPORTS; LETTER [Nm] Nome de substância: 0 (Anesthetics, Local); 0 (Drug Combinations); 0 (Vasoconstrictor Agents); 98PI200987 (Lidocaine); YKH834O4BH (Epinephrine) [Em] Mês de entrada: 1712 [Cu] Atualização por classe: 171226 [Lr] Data última revisão: 171226 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170505 [St] Status: MEDLINE [do] DOI: 10.3341/kjo.2017.0004

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[PMID]: 28470326 [Au] Autor: Puslecki M; Perek B; Stefaniak S; Siniawski A; Oszkinis G; Jemielity M [Ad] Endereço: Department of Cardiac Surgery and Transplantology, Poznan University of Medical Sciences, Poznan, Poland. [Ti] Título: Successful surgical treatment of a subtotal descending aortic occlusion. [So] Source: Cardiovasc J Afr;28(2):e1-e3, 2017 Apr 23. [Is] ISSN: 1680-0745 [Cp] País de publicação: South Africa [La] Idioma: eng [Ab] Resumo: We present the case of a 33-year-old man with middle aortic syndrome. The final diagnosis was established with magnetic resonance imaging. He underwent a successful aorto-aortic bypass. Two-year follow-up imaging showed the new graft was patent, with no abnormalities at the anastomosis sites. At the last follow-up examination he was asymptomatic with no neurological dysfunction. [Mh] Termos MeSH primário: Aorta Torácica/cirurgia Doenças da Aorta/cirurgia Arteriopatias Oclusivas/cirurgia Implante de Prótese Vascular [Mh] Termos MeSH secundário: Adulto Aorta Torácica/diagnóstico por imagem Aorta Torácica/fisiopatologia Doenças da Aorta/diagnóstico por imagem Doenças da Aorta/fisiopatologia Arteriopatias Oclusivas/diagnóstico por imagem Arteriopatias Oclusivas/fisiopatologia Prótese Vascular Implante de Prótese Vascular/instrumentação Seres Humanos Angiografia por Ressonância Magnética Masculino Polietilenotereftalatos Desenho de Prótese Fatores de Tempo Resultado do Tratamento Grau de Desobstrução Vascular [Pt] Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE [Nm] Nome de substância: 0 (Polyethylene Terephthalates) [Em] Mês de entrada: 1712 [Cu] Atualização por classe: 171218 [Lr] Data última revisão: 171218 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170505 [St] Status: MEDLINE [do] DOI: 10.5830/CVJA-2016-012

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[PMID]: 28471609 [Au] Autor: Tanne D [Ad] Endereço: Department of Neurology, Sagol Neuroscience Center, Sheba Medical Center, Tel Hashomer, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. [Ti] Título: Endovascular Treatment for Acute Large Artery Occlusion Stroke: Implications for Israel. [So] Source: Isr Med Assoc J;18(9):569-570, 2016 Sep. [Is] ISSN: 1565-1088 [Cp] País de publicação: Israel [La] Idioma: eng [Mh] Termos MeSH primário: Isquemia Encefálica/terapia Procedimentos Endovasculares/métodos Acidente Vascular Cerebral/terapia [Mh] Termos MeSH secundário: Adulto Arteriopatias Oclusivas/complicações Isquemia Encefálica/epidemiologia Isquemia Encefálica/patologia Seres Humanos Israel Acidente Vascular Cerebral/epidemiologia Acidente Vascular Cerebral/patologia [Pt] Tipo de publicação: EDITORIAL [Em] Mês de entrada: 1711 [Cu] Atualização por classe: 171128 [Lr] Data última revisão: 171128 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170505 [St] Status: MEDLINE

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[PMID]: 29019892 [Au] Autor: Kang JH; Yun TJ; Yoo RE; Yoon BW; Lee AL; Kang KM; Choi SH; Kim JH; Sohn CH; Han MH [Ad] Endereço: aInstitute of Radiation Medicine, Seoul National University Medical Research Center bDepartment of Radiology cClinical Research Center for Stroke, Clinical Research Institute dDepartment of Neurology, Seoul National University Hospital, Seoul eDepartment of Radiology, Soonchunhyang University Bucheon Hospital, Gyunggi-do, Republic of Korea. [Ti] Título: Bright sinus appearance on arterial spin labeling MR imaging aids to identify cerebral venous thrombosis. [So] Source: Medicine (Baltimore);96(41):e8244, 2017 Oct. [Is] ISSN: 1536-5964 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: Cerebral venous thrombosis is a potentially lethal disease. Early diagnosis is essential to improve its prognosis. However, its early diagnosis based on conventional imaging modalities remains a challenge in clinical settings. The purpose of this study was to evaluate whether bright sinus appearance on arterial spin-labeling perfusion-weighted image (ASL-PWI) could help identify cerebral venous thrombosis.ASL-PWI of 13 patients who were confirmed as cerebral venous thrombosis based on neurologic symptoms and computed tomography (CT) or magnetic resonance (MR) venography (with/without cerebral angiography) were retrospectively analyzed for the presence or absence of the following: bright signal in dural sinus termed "bright sinus appearance"; and hypoperfusion in brain parenchyma drained by thrombosed sinus. In addition, conventional MR findings, including susceptibility vessel sign, empty delta sign, and atypical distribution against arterial territory, were also analyzed.Bright sinus appearance on ASL-PWI was found in all (100%) 13 patients. In addition, 10 (77%) patients showed hypoperfusion in the brain parenchyma drained by thrombosed sinus on ASL-PWI. Susceptibility vessel sign and empty delta sign were revealed in 11 (85%) and 7 (54%) patients, respectively. Atypical distribution against arterial territory was seen in 5 (50%) of the 10 patients with parenchymal abnormality on conventional MR sequences. Therefore, the bright sinus appearance had higher sensitivities for identifying cerebral venous thrombosis than the susceptibility vessel sign, empty delta sign, and atypical distribution against arterial territory (with differences of 15%; P = .500, 46%; P = .031, and 50%; P = .031, respectively).Bright sinus appearance on ASL-PWI can provide important diagnostic clue for identifying cerebral venous thrombosis. Therefore, this technique may have the potential to be used as a noninvasive diagnostic tool to identify the cerebral venous thrombosis. [Mh] Termos MeSH primário: Arteriopatias Oclusivas/diagnóstico Artérias Cerebrais/diagnóstico por imagem Veias Cerebrais Trombose Intracraniana Imagem por Ressonância Magnética/métodos Trombose Venosa/diagnóstico [Mh] Termos MeSH secundário: Angiografia Cerebral/métodos Veias Cerebrais/diagnóstico por imagem Veias Cerebrais/patologia Diagnóstico Diferencial Feminino Seres Humanos Trombose Intracraniana/diagnóstico por imagem Trombose Intracraniana/patologia Masculino Meia-Idade Reprodutibilidade dos Testes República da Coreia Estudos Retrospectivos Marcadores de Spin [Pt] Tipo de publicação: JOURNAL ARTICLE; OBSERVATIONAL STUDY [Nm] Nome de substância: 0 (Spin Labels) [Em] Mês de entrada: 1710 [Cu] Atualização por classe: 171122 [Lr] Data última revisão: 171122 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 171012 [St] Status: MEDLINE [do] DOI: 10.1097/MD.0000000000008244

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