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  1 / 47926 MEDLINE  
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[PMID]:29489696
[Au] Autor:Ren H; Ma L; Wei M; Li J; Yu M; Yin L
[Ad] Endereço:Department of Neurosurgery, Tianjin Huanhu Hospital, Tianjin, China.
[Ti] Título:Duplicated middle cerebral artery origin with an aneurysm.
[So] Source:Medicine (Baltimore);97(9):e9947, 2018 Mar.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Middle cerebral artery (MCA) anomalies are relatively rare and often related to aneurysms. Familiarity with these anomalies is important in resolving problems that arise in the complex angioarchitecture. Reports often describe that aneurysms that are related to accessory or duplicated MCA are often located at its origin. PATIENT CONCERNS: A 59-year-old man presented with a headache for 10 days, without nausea and vomiting. The physical examination was negative. DIAGNOSIS: A computed tomography (CT) scan revealed an intracerebral hematoma in the deep right frontal lobe, near the caudate nucleus. Digital subtraction angiography (DSA) revealed an anomalous duplicated origin of the right MCA, with occlusion of the main MCA trunk as well as twisting and dilation of the accessory MCA trunk. A wide-necked aneurysm was located at a sharp curve of the tortuous accessory MCA trunk. A ruptured aneurysm related to a duplicated MCA origin was diagnosed. INTERVENTIONS: Open surgery was rejected by the patient; hence, palliative endovascular coil embolization of the larger daughter sac was performed. OUTCOMES: The postoperative course was uneventful. There was no rebleeding at 8-months follow-up. LESSONS: MCA anomalies are relatively rare and often related to aneurysms. It is important to be familiar with these anomalies as related lesions often manifest within a complex angioarchitecture. Aneurysms at the trunk of an anomalous MCA are a rare entity and open surgery may be recommended.
[Mh] Termos MeSH primário: Aneurisma Roto/diagnóstico por imagem
Aneurisma Intracraniano/diagnóstico por imagem
Artéria Cerebral Média/anormalidades
[Mh] Termos MeSH secundário: Aneurisma Roto/complicações
Angiografia Digital
Angiografia Cerebral
Cefaleia/diagnóstico por imagem
Cefaleia/etiologia
Seres Humanos
Aneurisma Intracraniano/complicações
Masculino
Meia-Idade
Artéria Cerebral Média/diagnóstico por imagem
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180307
[Lr] Data última revisão:
180307
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180301
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009947


  2 / 47926 MEDLINE  
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[PMID]:28741257
[Au] Autor:Joshi S; Rizzoli P; Loder E
[Ad] Endereço:Clinical Pharmacy Practice, MCPHS University College of Pharmacy, Worcester, USA.
[Ti] Título:The comorbidity burden of patients with cluster headache: a population-based study.
[So] Source:J Headache Pain;18(1):76, 2017 Dec.
[Is] ISSN:1129-2377
[Cp] País de publicação:Italy
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Evidence is limited regarding the comorbidity burden of patients with cluster headache (CH). We aimed to characterize comorbid conditions in a cohort of CH patients diagnosed by headache experts, using electronic health record information from the Partners Research Patient Data Registry (RPDR). METHODS: We identified and reviewed the charts of unique patients diagnosed by headache specialists over an 11-year period, and a set of matched controls. Patients were categorized as having Definite, Unconfirmed or no CH. We calculated the prevalence of and tested for statistically significant differences of selected comorbid conditions in these populations. RESULTS: An RPDR query identified 170 patients with a free text or ICD diagnosis of cluster headache. 15 records belonging to Partners employees were excluded. 75 patients met diagnostic criteria for CH (Definite CH). 22 had headaches with some features of CH but the diagnosis was uncertain (Unconfirmed CH). In 58 the diagnosis was determined to be inaccurate due to data entry errors. Patients with Definite CH had an average age of 43.4 years; 80% were male. The average time from CH onset to diagnosis was 12.7 years (range 1-51). The average number of yearly emergency department and outpatient visits for the group of Definite CH patients was 4.5 and 25.4, respectively, compared with 1.1 and 6.9 in controls. Of the 55 examined conditions, four were statistically significantly less common in patients with definite CH compared with controls (diabetes, musculoskeletal/orthopaedic problems, "other gastrointestinal diagnoses" and skin conditions) and four were statistically significantly more common (smoking, depression, dental disorders and deviated septum). CONCLUSIONS: In this large population-based study, we identified a surprisingly small number of patients who met strict diagnostic criteria for CH. In these patients, however, we identified a distinct pattern of selected comorbidities. The pattern is somewhat but not entirely consistent with that of the "classic" CH patient depicted in the medical literature. CH patients are frequently diagnosed with sinus or dental problems. Many experience substantial delay in receiving a diagnosis. These things may in part explain the high frequency of medical visits in this population. It is difficult to distinguish conditions that are genuinely comorbid with CH from those that reflect misdiagnoses or medical scrutiny of patients in frequent contact with the healthcare system.
[Mh] Termos MeSH primário: Cefaleia Histamínica/diagnóstico
Cefaleia Histamínica/epidemiologia
Efeitos Psicossociais da Doença
Vigilância da População
[Mh] Termos MeSH secundário: Adulto
Idoso
Estudos de Coortes
Comorbidade
Erros de Diagnóstico
Registros Eletrônicos de Saúde/tendências
Feminino
Seres Humanos
Masculino
Transtornos Mentais/diagnóstico
Transtornos Mentais/epidemiologia
Meia-Idade
Vigilância da População/métodos
Prevalência
Sistema de Registros
Fumar/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170726
[St] Status:MEDLINE
[do] DOI:10.1186/s10194-017-0785-3


  3 / 47926 MEDLINE  
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[PMID]:29489658
[Au] Autor:Huang KH; Tai MC; Lee LC; Weng TH; Chen YH; Lin LF; Chen JT; Lu DW; Chen CL
[Ad] Endereço:Department of Ophthalmology, Tri-Service General Hospital.
[Ti] Título:Positron emission tomography/computed tomography scan of Vogt-Koyanagi-Harada syndrome with associated autoimmune thyroid disease: A case report and literature review.
[So] Source:Medicine (Baltimore);97(9):e0047, 2018 Mar.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Vogt-Koyanagi-Harada (VKH) syndrome is a rare disease and could be associated with autoimmune thyroid disease (AITD). This report was aimed to investigate the utility of F-fludeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) for the diagnosis of VKH syndrome with AITD and to perform a literature review on the association between the 2 diseases. PATIENT CONCERNS: A 55-year-old woman without the history of ocular trauma suffered from chronic headache. She was presented with painful blurred vision of both eyes with headache for 2 weeks. Ophthalmic evaluations revealed panuveitis, exudative retinal detachment, and papilloedema in both eyes. The clinical symptoms and presentations are compatible with the diagnosis of VKH syndrome. Other examinations for intraocular infection, malignancy, and lupus choroidopathy were of negative results. The result of contrast-enhanced computed tomography (CT) of the brain was normal. Due to the history of cancer in the patient's families, a F-FDG PET/CT whole-body scan was performed. The result indicated a focal of 2-fluoro-2-deoxy-D-glucose (FDG) uptake at the right upper lobe of the thyroid. Therefore, the patient's thyroid function was examined and the result indicated euthyroidism with detectable thyroid peroxidase/thyroglobulin antibodies. DIAGNOSES: VKH syndrome with associated AITD. INTERVENTIONS: Treatment with intravenous pulse systemic methylprednisolone (1000 mg daily) was prescribed for 3 days and then shifted gradually to tapered oral steroid medication. OUTCOMES: Symptoms of papillitis and serous retinal detachment of VKH syndrome was relieved after steroid treatment LESSONS:: F-fludeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) can be used for the effective diagnosis of VKH syndrome with AITD.
[Mh] Termos MeSH primário: Tomografia Computadorizada com Tomografia por Emissão de Pósitrons
Tireoidite Autoimune/complicações
Tireoidite Autoimune/diagnóstico por imagem
Síndrome Uveomeningoencefálica/complicações
Síndrome Uveomeningoencefálica/diagnóstico por imagem
[Mh] Termos MeSH secundário: Feminino
Fluordesoxiglucose F18
Glucocorticoides/uso terapêutico
Cefaleia/etiologia
Seres Humanos
Metilprednisolona/uso terapêutico
Meia-Idade
Tireoidite Autoimune/tratamento farmacológico
Síndrome Uveomeningoencefálica/tratamento farmacológico
Transtornos da Visão/etiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Glucocorticoids); 0Z5B2CJX4D (Fluorodeoxyglucose F18); X4W7ZR7023 (Methylprednisolone)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180301
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000010047


  4 / 47926 MEDLINE  
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[PMID]:29386181
[Au] Autor:Adelborg K; Szépligeti SK; Holland-Bill L; Ehrenstein V; Horváth-Puhó E; Henderson VW; Sørensen HT
[Ad] Endereço:Department of Clinical Epidemiology, Aarhus University Hospital, Denmark kade@clin.au.dk.
[Ti] Título:Migraine and risk of cardiovascular diseases: Danish population based matched cohort study.
[So] Source:BMJ;360:k96, 2018 01 31.
[Is] ISSN:1756-1833
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To examine the risks of myocardial infarction, stroke (ischaemic and haemorrhagic), peripheral artery disease, venous thromboembolism, atrial fibrillation or atrial flutter, and heart failure in patients with migraine and in a general population comparison cohort. DESIGN: Nationwide, population based cohort study. SETTING: All Danish hospitals and hospital outpatient clinics from 1995 to 2013. PARTICIPANTS: 51 032 patients with migraine and 510 320 people from the general population matched on age, sex, and calendar year. MAIN OUTCOME MEASURES: Comorbidity adjusted hazard ratios of cardiovascular outcomes based on Cox regression analysis. RESULTS: Higher absolute risks were observed among patients with incident migraine than in the general population across most outcomes and follow-up periods. After 19 years of follow-up, the cumulative incidences per 1000 people for the migraine cohort compared with the general population were 25 17 for myocardial infarction, 45 25 for ischaemic stroke, 11 6 for haemorrhagic stroke, 13 11 for peripheral artery disease, 27 18 for venous thromboembolism, 47 34 for atrial fibrillation or atrial flutter, and 19 18 for heart failure. Correspondingly, migraine was positively associated with myocardial infarction (adjusted hazard ratio 1.49, 95% confidence interval 1.36 to 1.64), ischaemic stroke (2.26, 2.11 to 2.41), and haemorrhagic stroke (1.94, 1.68 to 2.23), as well as venous thromboembolism (1.59, 1.45 to 1.74) and atrial fibrillation or atrial flutter (1.25, 1.16 to 1.36). No meaningful association was found with peripheral artery disease (adjusted hazard ratio 1.12, 0.96 to 1.30) or heart failure (1.04, 0.93 to 1.16). The associations, particularly for stroke outcomes, were stronger during the short term (0-1 years) after diagnosis than the long term (up to 19 years), in patients with aura than in those without aura, and in women than in men. In a subcohort of patients, the associations persisted after additional multivariable adjustment for body mass index and smoking. CONCLUSIONS: Migraine was associated with increased risks of myocardial infarction, ischaemic stroke, haemorrhagic stroke, venous thromboembolism, and atrial fibrillation or atrial flutter. Migraine may be an important risk factor for most cardiovascular diseases.
[Mh] Termos MeSH primário: Doenças Cardiovasculares/etiologia
Transtornos de Enxaqueca/complicações
Infarto do Miocárdio/etiologia
Acidente Vascular Cerebral/etiologia
[Mh] Termos MeSH secundário: Adulto
Fibrilação Atrial/epidemiologia
Fibrilação Atrial/etiologia
Índice de Massa Corporal
Doenças Cardiovasculares/epidemiologia
Estudos de Coortes
Comorbidade
Dinamarca/epidemiologia
Feminino
Insuficiência Cardíaca/epidemiologia
Insuficiência Cardíaca/etiologia
Seres Humanos
Incidência
Hemorragias Intracranianas/epidemiologia
Hemorragias Intracranianas/etiologia
Masculino
Meia-Idade
Transtornos de Enxaqueca/diagnóstico
Transtornos de Enxaqueca/epidemiologia
Infarto do Miocárdio/epidemiologia
Avaliação de Resultados (Cuidados de Saúde)
Doença Arterial Periférica/epidemiologia
Doença Arterial Periférica/etiologia
Estudos Prospectivos
Fatores de Risco
Fumar/epidemiologia
Acidente Vascular Cerebral/epidemiologia
Tromboembolia Venosa/epidemiologia
Tromboembolia Venosa/etiologia
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180202
[St] Status:MEDLINE
[do] DOI:10.1136/bmj.k96


  5 / 47926 MEDLINE  
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[PMID]:29223275
[Au] Autor:Correa V; Vintch J; Lanks C
[Ad] Endereço:Division of Pulmonary and Critical Care Physiology and Medicine, Harbor-UCLA Medical Center, Torrance, CA.
[Ti] Título:A 26-Year-Old Man From Mexico With Headaches, Dysuria, and a Right Scrotal Mass.
[So] Source:Chest;152(6):e147-e150, 2017 12.
[Is] ISSN:1931-3543
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:CASE PRESENTATION: A 26-year-old man with no medical history was admitted to the hospital for evaluation of his change in mental status. He was noted to be agitated at work and had difficulty walking for 2 days before being brought in to the ED by his family. According to his uncle, the patient had been complaining of a headache and pain with urination for approximately 1 week. He was born in Guerrero, Mexico (a small farm town), and moved to Los Angeles, California, in 2008.
[Mh] Termos MeSH primário: Disuria/etiologia
Cefaleia/etiologia
Hidrocefalia/complicações
Mycobacterium bovis/isolamento & purificação
Escroto/diagnóstico por imagem
Tuberculose dos Genitais Masculinos/diagnóstico
[Mh] Termos MeSH secundário: Adulto
DNA Bacteriano/análise
Diagnóstico Diferencial
Disuria/diagnóstico
Cefaleia/diagnóstico
Seres Humanos
Hidrocefalia/diagnóstico
Imagem por Ressonância Magnética
Masculino
Mycobacterium bovis/genética
Escroto/microbiologia
Tuberculose dos Genitais Masculinos/microbiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Bacterial)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171211
[St] Status:MEDLINE


  6 / 47926 MEDLINE  
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[PMID]:29469553
[Au] Autor:Goadsby PJ; Picard H; Mikol DD
[Ad] Endereço:King's College London, London, United Kingdom peter.goadsby@kcl.ac.uk
[Ti] Título:Preventive Therapies for Chronic Migraine.
[So] Source:N Engl J Med;378(8):774-5, 2018 02 22.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Bloqueadores dos Canais de Cálcio
Transtornos de Enxaqueca
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:LETTER; COMMENT
[Nm] Nome de substância:
0 (Calcium Channel Blockers)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180223
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMc1716990


  7 / 47926 MEDLINE  
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[PMID]:29469552
[Au] Autor:Balfagón G; Blanco-Rivero J; Márquez-Rodas I
[Ad] Endereço:Universidad Autónoma de Madrid, Madrid, Spain
[Ti] Título:Preventive Therapies for Chronic Migraine.
[So] Source:N Engl J Med;378(8):773-4, 2018 02 22.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Transtornos de Enxaqueca/prevenção & controle
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:LETTER; COMMENT
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180223
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMc1716990


  8 / 47926 MEDLINE  
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[PMID]:29466162
[Au] Autor:Silberstein SD; Yeung PP; Aycardi E
[Ad] Endereço:Thomas Jefferson University, Philadelphia, PA stephen.silberstein@jefferson.edu
[Ti] Título:Preventive Therapies for Chronic Migraine.
[So] Source:N Engl J Med;378(8):774, 2018 02 22.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Doença Crônica
Transtornos de Enxaqueca/prevenção & controle
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:LETTER; COMMENT
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180222
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMc1716990


  9 / 47926 MEDLINE  
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[PMID]:29466149
[Au] Autor:Knuesel SJ; Guseh JS; Karp Leaf R; Ciaranello AL; Eng GM
[Ad] Endereço:From the Departments of Medicine (S.J.K., J.S.G., R.K.L., A.L.C.) and Pathology (G.M.E.), Massachusetts General Hospital, and the Departments of Medicine (S.J.K., J.S.G., R.K.L., A.L.C.) and Pathology (G.M.E.), Harvard Medical School - both in Boston.
[Ti] Título:Case 6-2018: A 35-Year-Old Woman with Headache, Subjective Fever, and Anemia.
[So] Source:N Engl J Med;378(8):753-760, 2018 Feb 22.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Anemia Hemolítica Autoimune/diagnóstico
Anemia/etiologia
Eritema Infeccioso/diagnóstico
[Mh] Termos MeSH secundário: Adulto
Anemia Hemolítica Autoimune/etiologia
Doença de Crohn/complicações
Doença de Crohn/tratamento farmacológico
Diagnóstico Diferencial
Eritema Infeccioso/complicações
Feminino
Morte Fetal/etiologia
Febre/etiologia
Cefaleia/etiologia
Seres Humanos
Hospedeiro Imunocomprometido
Parvovirus B19 Humano/isolamento & purificação
Gravidez
Complicações Infecciosas na Gravidez
Viremia
[Pt] Tipo de publicação:CASE REPORTS; CLINICAL CONFERENCE; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180222
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMcpc1712223


  10 / 47926 MEDLINE  
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[PMID]:29390256
[Au] Autor:Yu W; Qu W; Wang Z; Xin C; Jing R; Shang Y; Zou H; Wang H; Feng S
[Ad] Endereço:Hematology Department, Yantai Affiliated Hospital, Binzhou Medical University, Yantai.
[Ti] Título:Sjogren's syndrome complicating pancytopenia, cerebral hemorrhage, and damage in nervous system: A case report and literature review.
[So] Source:Medicine (Baltimore);96(50):e8542, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Sjogren's syndrome(SS) is a chronic autoimmune disease, which damages exocrine glands especially salivary and lacrimal glands, with xerostomia and xerophthalmia as common symptoms. PATIENT CONCERNS: We report a case of a 49-year-old woman presented with pancytopenia. Her laboratory examinations lead us diagnose her as Sjogren's syndrome complicating pancytopenia. She had neurological symptoms during her treatment, which represent only 4.5% of Sjogren's syndrome complicating damage in nervous system. DIAGNOSES: Sjogren's syndrome complicating pancytopenia. INTERVENTIONS: Dexamethasone (40mg QD for 4 days) and immunoglobulin (25g QD for 2 days) were administered for intensive treatment followed by oral methylprednisolone 40mg QD as maintenance treatment. Total glucosides of paeony 0.6g TID and danazol 0.2g BID per os were given. We also gave her Piperacillin-tazobactam and moxifloxacin for anti-infection and Fluconazole for anti-fungal therapy, as well as other supportive treatments. OUTCOMES: Follow-up of the patient observed the normalization of peripheral blood cell count, immunity indices and neurological examinations 6 months after discharge. LESSONS: For patients presented with blood system abnormalities unilineage or multiple-lineage cytopenia in particular, history investigations and relevant examinations should be considered to exclude the existence of autoimmune diseases like Sjogren's syndrome.
[Mh] Termos MeSH primário: Hemorragia Cerebral/etiologia
Pancitopenia/etiologia
Síndrome de Sjogren/complicações
[Mh] Termos MeSH secundário: Dexametasona/uso terapêutico
Equimose/etiologia
Feminino
Glucocorticoides/uso terapêutico
Cefaleia/etiologia
Seres Humanos
Imunoglobulinas Intravenosas/uso terapêutico
Metilprednisolona/uso terapêutico
Meia-Idade
Convulsões/etiologia
Síndrome de Sjogren/tratamento farmacológico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Glucocorticoids); 0 (Immunoglobulins, Intravenous); 7S5I7G3JQL (Dexamethasone); X4W7ZR7023 (Methylprednisolone)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008542



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