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  1 / 1471 MEDLINE  
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[PMID]:29197467
[Au] Autor:González-Villanueva I; Silvestre Salvador JF
[Ad] Endereço:Servicio de Dermatología, Hospital General Universitario de Alicante - ISABIAL, Alicante, España. Electronic address: jolairis@gmail.com.
[Ti] Título:Diagnostic Tools to Use When We Suspect an Allergic Reaction to a Tattoo: A Proposal Based on Cases at Our Hospital.
[Ti] Título:¿Qué procedimientos diagnósticos deberíamos realizar ante una sospecha de reacción alérgica a un tatuaje? Propuesta basada en nuestra casuística..
[So] Source:Actas Dermosifiliogr;109(2):162-172, 2018 Mar.
[Is] ISSN:1578-2190
[Cp] País de publicação:Spain
[La] Idioma:eng; spa
[Ab] Resumo:INTRODUCTION: Tattooing has become a popular practice in western countries, particularly among younger populations. Tattoos, however, can cause complications, such as infections, allergic or foreign-body reactions, and even systemic inflammatory responses. PATIENTS AND METHODS: We conducted a retrospective study of all patients seen for tattoo-related complications at our skin allergy unit between January 2002 and December 2016. RESULTS: We studied 23 patients. Nine of these experienced early complications, all related to infection. The other 14 patients developed late reactions. Ten were diagnosed with probable allergic contact dermatitis to ink, but the suspect allergen was identified in just 3 cases and confirmed in just 1 of these. There were 2 cases of cutaneous sarcoidosis, 1 case of foreign body granuloma, and 1 case of neuropathy. CONCLUSIONS: Complications resulting from tattoos are relatively common dermatology complaints. Drawing from our experience, we propose a diagnostic algorithm designed to guide dermatologists in evaluating different reactions to tattoos and prescribing appropriate treatment.
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[St] Status:In-Process


  2 / 1471 MEDLINE  
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[PMID]:29422304
[Au] Autor:Ruiz-Villaverde R; Cuenca-Barrales C; Aguayo-Carreras P
[Ad] Endereço:Unidad de Gestión Clínica de Dermatología, Hospital Universitario Campus de la Salud, Granada, España. Electronic address: ismenios@hotmail.com.
[Ti] Título:[What the red stain of the tattoo hides].
[Ti] Título:Lo que la tinta roja del tatuaje esconde..
[So] Source:An Pediatr (Barc);, 2018 Feb 05.
[Is] ISSN:1695-9531
[Cp] País de publicação:Spain
[La] Idioma:spa
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180209
[Lr] Data última revisão:
180209
[St] Status:Publisher


  3 / 1471 MEDLINE  
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[PMID]:29025669
[Au] Autor:Huang N; Lin J; Li S; Deng Y; Kong S; Hong P; Yang P; Liao M; Hu Z
[Ad] Endereço:Faculty of Chemistry and Environment Science, Guangdong Ocean University, Zhanjiang 524088, PR China. Electronic address: huangn88@126.com.
[Ti] Título:Preparation and evaluation of squid ink polysaccharide-chitosan as a wound-healing sponge.
[So] Source:Mater Sci Eng C Mater Biol Appl;82:354-362, 2018 Jan 01.
[Is] ISSN:1873-0191
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:A new type of wound healing agent was developed using two marine biomaterials (squid ink polysaccharide and chitosan) as carriers and calcium chloride as an initiator for coagulation. Based on central composite design-response surface methodology, comprehensive evaluation of appearance quality for composite sponges and water absorbency were used as evaluation indices to identify the optimized preparation conditions and further evaluate the performance of the squid ink polysaccharide-chitosan sponge (SIP-CS). The optimized formulation of SIP-CS was as follows: chitosan concentration, 2.29%; squid ink polysaccharide concentration, 0.55%; and calcium chloride concentration, 2.82%, at a volume ratio of 15:5:2. SIP-CS was conducive to sticking on the wound, characterized by the spongy property, strong absorptivity, and tackiness. Rabbit ear arterial, hepatic, and femoral artery hemorrhage experiments indicated that, compared with chitosan dressings and absorbable gelatin, the hemostatic times were shorter and the bleeding volume was smaller. Furthermore, SIP-CS absorbed a large amount of hemocytes, leading to rapid hemostasis. The healing areas and wound pathological sections in scalded New Zealand rabbits indicated that SIP-CS promoted wound healing more rapidly than chitosan and better than commercially available burn cream. Thus, SIP-CS is a good wound healing agent for rapid hemostasis, promoting burn/scalded skin healing, and protecting from wound infection.
[Mh] Termos MeSH primário: Materiais Biocompatíveis/química
Quitosana/química
Decapodiformes/metabolismo
Tinta
Polissacarídeos/química
[Mh] Termos MeSH secundário: Adsorção
Animais
Artérias/lesões
Bandagens
Materiais Biocompatíveis/farmacologia
Células Sanguíneas/citologia
Células Sanguíneas/efeitos dos fármacos
Células Sanguíneas/metabolismo
Hemorragia/prevenção & controle
Microscopia Eletrônica de Varredura
Coelhos
Cicatrização/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biocompatible Materials); 0 (Polysaccharides); 9012-76-4 (Chitosan)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180205
[Lr] Data última revisão:
180205
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171014
[St] Status:MEDLINE


  4 / 1471 MEDLINE  
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[PMID]:27770630
[Au] Autor:Jang J; Park HJ; Kim SW; Kim H; Park JY; Na SJ; Kim HJ; Park MN; Choi SH; Park SH; Kim SW; Kwon SM; Kim PJ; Cho DW
[Ad] Endereço:Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-ro, Nam-gu, Pohang, Kyungbuk, 37673, South Korea.
[Ti] Título:3D printed complex tissue construct using stem cell-laden decellularized extracellular matrix bioinks for cardiac repair.
[So] Source:Biomaterials;112:264-274, 2017 01.
[Is] ISSN:1878-5905
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Stem cell therapy is a promising therapeutic method for the treatment of ischemic heart diseases; however, some challenges prohibit the efficacy after cell delivery due to hostile microenvironment of the injured myocardium. 3D printed pre-vascularized stem cell patch can enhance the therapeutic efficacy for cardiac repair through promotion of rapid vascularization after patch transplantation. In this study, stem cell-laden decellularized extracellular matrix bioinks are used in 3D printing of pre-vascularized and functional multi-material structures. The printed structure composed of spatial patterning of dual stem cells improves cell-to-cell interactions and differentiation capability and promotes functionality for tissue regeneration. The developed stem cell patch promoted strong vascularization and tissue matrix formation in vivo. The patterned patch exhibited enhanced cardiac functions, reduced cardiac hypertrophy and fibrosis, increased migration from patch to the infarct area, neo-muscle and capillary formation along with improvements in cardiac functions. Therefore, pre-vascularized stem cell patch provides cardiac niche-like microenvironment, resulting in beneficial effects on cardiac repair.
[Mh] Termos MeSH primário: Matriz Extracelular/química
Regeneração Tecidual Guiada/instrumentação
Infarto do Miocárdio/terapia
Impressão Tridimensional
Transplante de Células-Tronco/instrumentação
Tecidos Suporte
[Mh] Termos MeSH secundário: Animais
Sistema Livre de Células/química
Células Cultivadas
Regeneração Tecidual Guiada/métodos
Seres Humanos
Tinta
Camundongos
Camundongos Endogâmicos BALB C
Camundongos Nus
Infarto do Miocárdio/patologia
Infarto do Miocárdio/fisiopatologia
Ratos
Ratos Endogâmicos F344
Transplante de Células-Tronco/métodos
Suínos
Engenharia Tecidual/instrumentação
Engenharia Tecidual/métodos
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180106
[Lr] Data última revisão:
180106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161023
[St] Status:MEDLINE


  5 / 1471 MEDLINE  
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[PMID]:28734603
[Au] Autor:Zang X; Liang W; Chang Q; Wu T; Wang C; Wang Z
[Ad] Endereço:Department of Chemistry, College of Science, Hebei Agricultural University, Baoding 071001, China.
[Ti] Título:Determination of volatile organic compounds in pen inks by a dynamic headspace needle trap device combined with gas chromatography-mass spectrometry.
[So] Source:J Chromatogr A;1513:27-34, 2017 Sep 01.
[Is] ISSN:1873-3778
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Some harmful volatile organic compounds (VOCs), such as methylbenzene, ethylbenzene, xylene, chlorobenzene and bromobenzene, are the commonly found chemicals in pen inks. In this work, a dynamic headspace needle-trap device (D-HS-NTD) with a ZIF-8-derived nanoporous carbon (ZIF-8-NPC) as the adsorbent was developed for the extraction of some VOCs in different pen inks prior to GC-MS detection. The main important influencing experimental parameters including the flow rate of the purge gas N , extraction temperature, extraction time, desorption temperature and desorption time for the extraction were optimized to obtain a high extraction efficiency. Under the optimized conditions, a good linearity was obtained in the concentration range of 0.1-400µgkg with the correlation coefficients (r) ranging from 0.9911 to 0.9990 for the eleven VOCs. The LODs at a signal-to-noise ratio of 3 (S/N=3) were measured to be 10-20ngkg for the VOCs. The developed method was applied to determine the VOCs from 20 pen inks. The recoveries of the VOCs for the method at the spiking levels of 0.5 and 20.0µgkg fell in the range from 80.0% to 108%.
[Mh] Termos MeSH primário: Carbono/química
Cromatografia Gasosa-Espectrometria de Massas/métodos
Tinta
Compostos Orgânicos Voláteis/análise
[Mh] Termos MeSH secundário: Adsorção
Agulhas
Porosidade
Sensibilidade e Especificidade
Razão Sinal-Ruído
Propriedades de Superfície
Temperatura Ambiente
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Volatile Organic Compounds); 7440-44-0 (Carbon)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170825
[Lr] Data última revisão:
170825
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170724
[St] Status:MEDLINE


  6 / 1471 MEDLINE  
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[PMID]:28496449
[Au] Autor:Grimplet J; Tello J; Laguna N; Ibáñez J
[Ad] Endereço:Departamento de Viticultura, Instituto de Ciencias de la Vid y del Vino (Consejo Superior de Investigaciones Científicas, Universidad de La Rioja, Gobierno de La Rioja)Logroño, Spain.
[Ti] Título:Differences in Flower Transcriptome between Grapevine Clones Are Related to Their Cluster Compactness, Fruitfulness, and Berry Size.
[So] Source:Front Plant Sci;8:632, 2017.
[Is] ISSN:1664-462X
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Grapevine cluster compactness has a clear impact on fruit quality and health status, as clusters with greater compactness are more susceptible to pests and diseases and ripen more asynchronously. Different parameters related to inflorescence and cluster architecture (length, width, branching, etc.), fruitfulness (number of berries, number of seeds) and berry size (length, width) contribute to the final level of compactness. From a collection of 501 clones of cultivar Garnacha Tinta, two compact and two loose clones with stable differences for cluster compactness-related traits were selected and phenotyped. Key organs and developmental stages were selected for sampling and transcriptomic analyses. Comparison of global gene expression patterns in flowers at the end of bloom allowed identification of potential gene networks with a role in determining the final berry number, berry size and ultimately cluster compactness. A large portion of the differentially expressed genes were found in networks related to cell division (carbohydrates uptake, cell wall metabolism, cell cycle, nucleic acids metabolism, cell division, DNA repair). Their greater expression level in flowers of compact clones indicated that the number of berries and the berry size at ripening appear related to the rate of cell replication in flowers during the early growth stages after pollination. In addition, fluctuations in auxin and gibberellin signaling and transport related gene expression support that they play a central role in fruit set and impact berry number and size. Other hormones, such as ethylene and jasmonate may differentially regulate indirect effects, such as defense mechanisms activation or polyphenols production. This is the first transcriptomic based analysis focused on the discovery of the underlying gene networks involved in grapevine traits of grapevine cluster compactness, berry number and berry size.
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170816
[Lr] Data última revisão:
170816
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.3389/fpls.2017.00632


  7 / 1471 MEDLINE  
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[PMID]:28430022
[Au] Autor:Domeño C; Aznar M; Nerín C; Isella F; Fedeli M; Bosetti O
[Ad] Endereço:a Instituto de Investigación en Ingeniería de Aragón (I3A), Depto. Química Analítica , Universidad de Zaragoza , Zaragoza , Spain.
[Ti] Título:Safety by design of printed multilayer materials intended for food packaging.
[So] Source:Food Addit Contam Part A Chem Anal Control Expo Risk Assess;34(7):1239-1250, 2017 Jul.
[Is] ISSN:1944-0057
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Printing inks are commonly used in multilayer plastics materials used for food packaging, and compounds present in inks can migrate to the food either by diffusion through the multilayers or because of set-off phenomena. To avoid this problem, the right design of the packaging is crucial. This paper studies the safety by design of multilayer materials. First, the migration from four different multilayers manufactured using polyethylene terephthalate (PET), aluminium (Al) and polyethylene (PE) was determined. The structural differences among materials such as the presence of inks or lacquer coatings as well as the differences in layers position allowed the study of a safety-by-design approach. Sixty-nine different compounds were detected and identified; 49 of them were not included in the positive list of Regulation EU/10/2011 or in Swiss legislation and 15 belong to Cramer class III, which means that they have a theoretical high toxicity. Some of the compounds related to ink composition were pyrene, a compound commercially used to make dyes and dye precursors and the antioxidant Irganox 1300. The application of external lacquers decreased the concentration of some migrants but also brought the potential for new migrants coming from its composition. A final risk assessment of the material allowed evaluating food safety for different food simulants and confirm it.
[Mh] Termos MeSH primário: Contaminação de Alimentos/prevenção & controle
Embalagem de Alimentos
Inocuidade dos Alimentos
Tinta
[Mh] Termos MeSH secundário: Difusão
Contaminação de Alimentos/análise
Medição de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170422
[St] Status:MEDLINE
[do] DOI:10.1080/19440049.2017.1322221


  8 / 1471 MEDLINE  
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[PMID]:28402968
[Au] Autor:Yeo MG; Kim GH
[Ad] Endereço:Department of Biomechatronic Engineering, College of Biotechnology and Bioengineering, Sungkyunkwan University (SKKU), Suwon, Republic of Korea.
[Ti] Título:A cell-printing approach for obtaining hASC-laden scaffolds by using a collagen/polyphenol bioink.
[So] Source:Biofabrication;9(2):025004, 2017 Apr 12.
[Is] ISSN:1758-5090
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:In the cell-printing process, bioink has been considered as an extremely important component for successful fabrication of macroscale cell-laden structures. Bioink should be non-toxic, biocompatible, and printable. To date, alginate has been widely used as a whole or partial component of bioink because it is non-toxic to embedded cells and even it can provide good printability with rapid gelation under calcium ions. However, alginate bioinks do not possess cell-activating ability. To overcome the shortcomings of alginate-based bioinks, a new collagen bioink, which was mixed with human adipose stem cells (hASCs) and crosslinked with a polyphenol (tannic acid), was proposed. The feasibility of the bioink was demonstrated using several in vitro assessments for comparison of the macroscale porous cell-laden collagen/polyphenol structure containing the hASCs with the conventional alginate-based cell-laden structure. The levels of the metabolic activity, including the cell viability and cell proliferation, of the cell-laden collagen structure were significantly higher than those of the control (alginate-based cell-laden structure). The results show that the newly designed bioink and cell-laden structure are potentially new outstanding components for regeneration of various tissues.
[Mh] Termos MeSH primário: Tecido Adiposo/citologia
Colágeno/farmacologia
Tinta
Polifenóis/farmacologia
Impressão Tridimensional
Células-Tronco/citologia
Tecidos Suporte/química
[Mh] Termos MeSH secundário: Animais
Morte Celular/efeitos dos fármacos
Células Cultivadas
Reagentes para Ligações Cruzadas/farmacologia
Módulo de Elasticidade
Elasticidade
Regulação da Expressão Gênica/efeitos dos fármacos
Seres Humanos
Camundongos
Imagem Óptica
Porosidade
Células-Tronco/efeitos dos fármacos
Células-Tronco/ultraestrutura
Sus scrofa
Taninos/química
Taninos/farmacologia
Taninos/toxicidade
Viscosidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Cross-Linking Reagents); 0 (Polyphenols); 0 (Tannins); 9007-34-5 (Collagen)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170424
[Lr] Data última revisão:
170424
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170414
[St] Status:MEDLINE
[do] DOI:10.1088/1758-5090/aa6997


  9 / 1471 MEDLINE  
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[PMID]:28302515
[Au] Autor:Scarpa M; Stegemann S; Hsiao WK; Pichler H; Gaisford S; Bresciani M; Paudel A; Orlu M
[Ad] Endereço:School of Pharmacy, University College London (UCL), London, United Kingdom.
[Ti] Título:Orodispersible films: Towards drug delivery in special populations.
[So] Source:Int J Pharm;523(1):327-335, 2017 May 15.
[Is] ISSN:1873-3476
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Orodispersible films (ODF) hold promise as a novel delivery method, with the potential to deliver tailored therapies to different patient populations. This article reviews the current strides of ODF technology and some of its unmet quality and manufacturing aspects. A topic highlights opportunities and limitations of inkjet printed ODF as a population-specific drug delivery. Overall, this article aims to stimulate further research to fill the current knowledge gap between manufacturing and administration requirements of ODF targeting specific patient subpopulations such as geriatrics.
[Mh] Termos MeSH primário: Sistemas de Liberação de Medicamentos
[Mh] Termos MeSH secundário: Administração Oral
Química Farmacêutica
Seres Humanos
Tinta
Polímeros
Impressão
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Polymers)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170807
[Lr] Data última revisão:
170807
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170318
[St] Status:MEDLINE


  10 / 1471 MEDLINE  
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[PMID]:28288467
[Au] Autor:Serup J
[Ad] Endereço:The 'Tattoo Clinic', Department of Dermatology, Bispebjerg University Hospital, Copenhagen, Denmark.
[Ti] Título:Tattoo Infections, Personal Resistance, and Contagious Exposure through Tattooing.
[So] Source:Curr Probl Dermatol;52:30-41, 2017.
[Is] ISSN:1662-2944
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Bacterial infection of tattoos remains a common complication. Pyogenic bacteria can cause infections shortly after the tattoo is made. Severity of infection varies from minor to major, ultimately with life-threatening septicemia. Viral infections may be introduced, i.e. HVB, HVC, and HIV. The risk of infection depends on the following triad: microbial pathogen and its aggressiveness, individual resistance of the tattooed, and inoculation and exposures by the tattoo needle and in the tattoo parlor. Some infectious risks can be controlled. Persons with weaknesses can refrain from tattooing. Tattoo parlors and tattooing can be hygienic and clean albeit not sterile; much has improved helped by hygiene guidelines of professional tattooists' organizations and through control instituted by local and national authorities. Tattoo inks remain a potential source of infection difficult to control in a low-priced competitive market operating over the Internet and across national borders. Ten percent of new inks are contaminated with bacteria pathogenic to humans, independent of a claim of 'sterility'. Known brands and established manufacturers are considered safer. Work is in progress aiming at common European standards for tattoo hygiene. Doctors have a role not only in treating tattoo infections but also in reporting cases to the competent authority in their country to support the monitoring of tattoo infections at any time, as an instrument for the authority to detect local outbreaks of tattoo infections early and prevent that new tattoo customers become infected. It is a potential risk of the future that new and very aggressive bacteria not seen in the past may unexpectedly show up in the tattoo scene.
[Mh] Termos MeSH primário: Dermatopatias Bacterianas/etiologia
Tatuagem/efeitos adversos
[Mh] Termos MeSH secundário: Contraindicações
Dinamarca
Contaminação de Equipamentos
Europa (Continente)
Seres Humanos
Higiene/normas
Tolerância Imunológica
Tinta
Agulhas/efeitos adversos
Agulhas/microbiologia
Fatores de Risco
Dermatopatias Bacterianas/microbiologia
Tatuagem/normas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170314
[St] Status:MEDLINE
[do] DOI:10.1159/000450777



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