Database : IBECS
Search on : G09.330.380.925 [DeCS Category]
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Id: 188820
Author: Choi, Marcelo; Aiello, Ernesto Alejandro; Ennis, Irene L; Villa-Abrille, María Celeste.
Title: El SRAA y el SARS-CoV-2: el acertijo a resolver / The RAAS and SARS-CoV-2: ariddle to solve
Source: Hipertens. riesgo vasc;37:0-0, 2020.
Language: es.
Abstract: El 31 de diciembre de 2019 se reportó el primer caso de COVID-19 en Wuhan, China, y desde entonces ha habido un interés creciente y sin precedentes por conocer todos los aspectos vinculados con esta nueva enfermedad. Uno de los temas que ha generado debate se vincula con la asociación entre la terapia antihipertensiva con inhibidores del sistema renina-angiotensina-aldosterona (SRAA) y la infección por el virus SARS-CoV-2. Si bien muchas preguntas siguen hoy día sin poder ser respondidas, la intención de este comunicado es informar a los profesionales de la salud acerca del estado actual de conocimiento. Dado que este es un tema en constante evolución, se recomienda su actualización a medida que se presenten nuevas evidencias. A continuación, daremos revisión a los estudios preclínicos y clínicos que relacionan el coronavirus con el SRAA

The first case of COVID-19 was reported on 31 December 2019 in Wuhan, China. Ever since there has been unprecedented and growing interest in learning about all aspects of this new disease. Debate has been generated as tothe association between antihypertensive therapy with renin-angiotensin-aldosterone system (RAAS) inhibitors and SARS-CoV-2 infection. While many questions as yet remain unanswered, the aim of this report is to inform healthprofessionals about the current state of knowledge. Because this is an ever-evolvingtopic, the recommendation is that it be updated as new evidence becomes available. Below, we provide a review of pre-clinical and clinical studies that link coronavirus to the RAAS
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Id: 184459
Author: Arenas-Beltrán, Mayra A; Ricaurte-Fajardo, Andrés; Ocampo-Navia, María Isabel; Baracaldo, Iván; Mejía, Juan A; Coral-Casas, Juliana.
Title: Síndrome de vasoconstricción cerebral reversible secundario a un paraganglioma yugular secretor de metanefrinas / Reversible cerebral vasoconstriction syndrome secondary to secreting jugular paraganglioma
Source: Rev. neurol. (Ed. impr.);69(5):220-222, 1 sept., 2019. ilus.
Language: es.
Abstract: No disponible
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Id: 183437
Author: Cavallasca, Javier A; Riera, Julia L; Musuruana, Jorge L.
Title: Borramiento de huellas dactilares debido a fenómeno de Raynaud / Loss of fingerprints due to Raynaud's phenomenon
Source: Med. clín (Ed. impr.);153(3):127-128, ago. 2019. ilus.
Language: es.
Abstract: No disponible
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Id: 180657
Author: Coral-Casas, Juliana; Ricaurte-Fajardo, Andrés; McCormick, Silvia J; Baracaldo, Iván; Jiménez, Camilo A; Mejía, Juan A.
Title: Síndrome de vasoconstricción cerebral reversible asociado a anastrozol: una causa inusual de alto impacto / Reversible cerebral vasoconstriction syndrome associated with anastrozole: an unusual cause of high impact
Source: Rev. neurol. (Ed. impr.);68(6):250-254, 16 mar., 2019. ilus, graf.
Language: es.
Abstract: Introducción. El síndrome de vasoconstricción cerebral reversible (SVCR) es una entidad de baja incidencia, de etiología multifactorial y amplio espectro de presentación. El principal síntoma es la cefalea de tipo trueno. Puede estar acompañado de focalización neurológica y cursar con desenlaces clínicos variable que incluso pueden llevar a la muerte. El diagnóstico es clínico e imaginológico, y el tratamiento incluye adoptar medidas generales de monitorización, manejo sintomático, identificar la etiología y actuar sobre ella para evitar recurrencia. Caso clínico. Mujer de 71 años con antecedente de cáncer de seno, tratada inicialmente con tamoxifeno; por presentar urticaria, se escalonó tratamiento con anastrozol. Ingresó por cefalea de tipo trueno, afasia anterior y somnolencia. La paciente refirió un evento similar una semana antes del ingreso. En la resonancia magnética cerebral evidenció una hemorragia subaracnoidea (HSA) pequeña de la convexidad temporoparietal izquierda, y la panangiografía documentó vasoespasmo en la región parietal posterior, lo que confirmó el diagnóstico de SVCR más HSA. Durante el ingreso presentó tres eventos de iguales características, que requirieron monitorización intensiva y dos panangiografías terapéuticas con nimodipino intraarterial, con posterior resolución del vasoespasmo. Permanece asintomática seis meses después. Conclusión. El SVCR constituye un reto diagnóstico dada su presentación variable y su etiología multifactorial. En este caso, el SVCR más HSA está asociado al uso de anastrozol. Hasta el momento no hay casos descritos de inhibidores de la aromatasa asociados a esta patología, que debe comunicarse para su farmacovigilancia

Introduction. Reversible cerebral vasoconstriction syndrome (RCVS) is a low incidence disability with a multifactorial etiology and a wide array of symptoms. The main symptom is a thunderclap headache, accompanied sometimes with various neurological deficits that can lead to death. RCVS is usually diagnosed through radiological imaging technology. The treatment includes adopting general measures of monitoring, symptomatic management, identifying the etiology and acting on it to avoid recurrence. Case report. A 71-year-old woman with a history of breast cancer originally treated with tamoxifen. Due to urticaria, the anastrozole management was staggered. She was admitted for aphasia, drowsiness and a thunderclap headache. The patientreported a similar event two weeks prior admission. In rain resonance, there was evidence of small sub-arachnoidal haemorrhage (SAH) of the left parietal temporal convexity and cerebral angiography. As well as documented vasospasm in the posterior parietal region confirming the diagnosis of RCVS plus SAH. During the stay, she presented three events with the same characteristics, requiring intensive monitoring and two therapeutic panangiographies with intra-arterial nimodipine with subsequent resolution of the vessel spasm. The patient remains asymptomatic six months later. Conclusion. RCVS is difficult to diagnose given its wide array of symptoms and multifactorial etiology. In this case, RCVS plus SAH is associated with the use of anastrozole. So far there are no reported cases of aromatase inhibitors associated with this pathology and should be reported in the literature for pharmacovigilance
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Id: 174982
Author: Castaño Ruiz, Isabel; Jiménez Velázquez, Raquel; Lova Navarro, Miguel; Delgado Marín, Juan Luis; Araico Rodríguez, Fernando.
Title: Una biopsia corial que da en el clavo: síndrome de Nicolau en gestante / A chorionic biopsy with fortuitous results: Nícolau syndrome in pregnant women
Source: Prog. obstet. ginecol. (Ed. impr.);61(4):384-386, jul.-ago. 2018. ilus.
Language: es.
Abstract: Presentamos a una gestante de 40 años, en la semana 12+6. Al obtener riesgo alto en el cribado del primer trimestre, se procedió a la biopsia corial por vía abdominal. Cuando se introdujo el anestésico local, la paciente comenzó con un dolor punzante sobre la zona de inyección, cambiando inmediatamente de color a rojo vinoso. Tras consultar con dermatología, se diagnosticó de síndrome de Nicolau, un vasoespasmo agudo por la inyección intraarterial de anestésico, que lleva a necrosis del tegumento cutáneo subsidiario a este. Dada la escasa prevalencia de esta afección, consideramos necesario elaborar una revisión bibliográfica sobre este síndrome

We present a 40-year-old pregnant woman, at week 12 + 6. By getting high risk in the first three months period screening, we abdominally proceeded to chorionic villus sampling. When the local anesthetic was introduced, the patient began with a shooting pain on the injection site, changing into a wine-red colour. After consultating with dermatology, she was diagnosed with Nicolau syndrome, an acute vasospasm by intra-arterial injection of anesthetic, leading to necrosis of the skin integument that depends on this. Given the low prevalence of this condition, we consider necessary to develop a literature review on this syndrome
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Id: 173327
Author: Torre-Colmenero, Juan de Dios de la; Arjona-Padillo, Antonio; Fernández-Pérez, Javier.
Title: Síndrome de vasoconstricción cerebral reversible tras abandono de hábito tabáquico y tratamiento con bupropión / Reversible cerebral vasoconstriction syndrome following smoking cessation and treatment with bupropion
Source: Rev. neurol. (Ed. impr.);66(9):322-323, 1 mayo, 2018.
Language: es.
Abstract: No disponible
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Id: 172444
Author: Accinelli, Roberto Alfonso; Marianella López, Lidia.
Title: Enfermedades por exposición a la altura / Altitude-Related Illnesses
Source: Arch. bronconeumol. (Ed. impr.);54(3):115-116, mar. 2018.
Language: es.
Abstract: No disponible
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Id: 168401
Author: Stojic, Isidora; Srejovic, Ivan; Zivkovic, Vladimir; Jeremic, Nevena; Djuric, Marko; Stevanovic, Ana; Milanovic, Tamara; Djuric, Dragan; Jakovljevic, Vladimir.
Title: The effects of verapamil and its combinations with glutamate and glycine on cardiodynamics, coronary flow and oxidative stress in isolated rat heart
Source: J. physiol. biochem;73(1):141-153, feb. 2017. tab, graf.
Language: en.
Abstract: The role of N-methyl-D-aspartate receptor (NMDA-R) in heart is still unclear. For these ionotropic glutamate receptors is characteristic the necessity of both co-agonists, glutamate and glycine, for their activation, which primarily allows influx of calcium. The aim of the present study was to examine the effects of verapamil, as a calcium channel blocker, alone and its combination with glycine and/or glutamate on cardiac function, coronary flow, and oxidative stress in isolated rat heart or to examine the effects of potential activation of NMDA-R in isolated rat heart. The hearts of male Wistar albino rats were excised and perfused according to Langendorff technique, and cardiodynamic parameters and coronary flow were determined during the administration of verapamil and its combinations with glutamate and/or glycine. The oxidative stress biomarkers, including thiobarbituric acid-reactive substances, nitrites, superoxide anion radical, and hydrogen peroxide, were each determined spectrophotometrically from coronary venous effluent. The greatest decline in parameters of cardiac contractility and systolic pressure was in the group that was treated with verapamil only, while minimal changes were observed in group treated with all three tested substances. Also, the largest changes in coronary flow were in the group treated only with verapamil, and at least in the group that received all three tested substances, as well as the largest increase in oxidative stress parameters. Based on the obtained results, it can be concluded that NMDA-R activation allows sufficient influx of calcium to increase myocardial contractility and systolic pressure, as well as short-term increase of oxidative stress (AU)

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Id: 168059
Author: Holanda Peña, Marisol; Chicote Álvarez, Enrique; Vázquez Higuera, José Luis.
Title: Síndrome de vasoconstricción cerebral reversible de evolución mortal / Fulminant reversible cerebral vasoconstriction syndrome
Source: Med. clín (Ed. impr.);149(9):417-418, nov. 2017. ilus.
Language: es.
Abstract: No disponible
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Id: 161923
Author: Rubio Gracia, J; Sánchez Marteles, M; Pérez Calvo, JI.
Title: Implicación de la congestión venosa sistémica en la insuficiencia cardíaca / Involvement of systemic venous congestion in heart failure
Source: Rev. clín. esp. (Ed. impr.);217(3):161-169, abr. 2017. ilus.
Language: es.
Abstract: La congestión venosa sistémica ha cobrado mucha importancia en la interpretación de la fisiopatología de la insuficiencia cardíaca aguda, y muy especialmente en el desarrollo del deterioro de la función renal durante las agudizaciones. En el presente trabajo se revisa el concepto, la caracterización clínica y la identificación de la congestión venosa. Se actualiza el conocimiento sobre su importancia en la fisiopatología de la insuficiencia cardíaca aguda y su implicación en el pronóstico. Se presta especial atención a la relación entre la congestión abdominal, el intersticio pulmonar como membrana filtrante, los fenómenos inflamatorios y el deterioro de la función renal en la insuficiencia cardíaca aguda. Por último, se revisa la descongestión como un novedoso objetivo terapéutico y los medios disponibles para su evaluación (AU)

Systemic venous congestion has gained significant importance in the interpretation of the pathophysiology of acute heart failure, especially in the development of renal function impairment during exacerbations. In this study, we review the concept, clinical characterisation and identification of venous congestion. We update current knowledge on its importance in the pathophysiology of acute heart failure and its involvement in the prognosis. We pay special attention to the relationship between abdominal congestion, the pulmonary interstitium as filtering membrane, inflammatory phenomena and renal function impairment in acute heart failure. Lastly, we review decongestion as a new therapeutic objective and the measures available for its assessment (AU)
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