Base de dados : IBECS
Pesquisa : B01.650.940.800.575.912.250.618.100.050.060.600 [Categoria DeCs]
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Fotocópia
Id: 192024
Autor: Armentia, A; Martín-Armentia, S; Pineda, F; Martín-Armentia, B; Castro, M; Fernández, S; Moro, A; Castillo, M.
Título: Allergic hypersensitivity to garlic and onion in children and adults
Fonte: Allergol. immunopatol;48(3):232-236, mayo-jun. 2020. tab, graf.
Idioma: en.
Resumo: BACKGROUND: China and Spain are world leaders in the consumption of edible bulbs (garlic and onion), but there are few references to their capacity to cause allergic symptoms. The target was to study allergic sensitization and clinical symptoms associated with garlic and onion consumption in a large sample of allergic patients. METHODS: An observational cross-sectional study was conducted, testing garlic and onion extracts in 8109 patients of all ages seen by our allergy clinic in 2018. Forty-four aeroallergens and foods were tested, including garlic and onion, with prick test and determination of specific IgE. Oral provocation and contact tests were performed if a delayed reaction was suspected. Western Blot was performed in the serum of patients positive to garlic and onion. RESULTS: We conducted 356,798 skin tests and 4254 specific IgE determinations. Of the 8109 patients tested, 2508 (30.92%) presented with symptoms associated with food intake and, in these patients, food hypersensitivity was detected by skin test, positive specific IgE or provocation in 924 patients, and was caused by garlic or onions in 27, indicating a prevalence of 2.92%. Immunodetection showed an association between the symptoms and a specific LTP to these bulbs, without cross-reactivity with other LTPs in the Mediterranean diet (peach, wheat). CONCLUSIONS: Allergic hypersensitivity to garlic and onions should not be underestimated and, given their high consumption, should be included in the diagnostic food allergy battery

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Fotocópia
Id: 77017
Autor: Martínez-Gimeno, A.
Título: Onions, myths, beliefs, fashion and reality in asthma
Fonte: Allergol. immunopatol;37(6):309-313, nov.-dic. 2009. tab.
Idioma: en.
Resumo: Some myths and unsupported beliefs about asthma are very popular and enjoy general public acceptance and fairly strong support on the Internet. Onions for cough; dairy products avoidance for asthma; and some other popular myths are reviewed, along with some other medical and mixed (popular and medical) myths comparing their popular and scientific support. Classifying medical statements as realities or unsupported beliefs is a hard and serious work nowadays addressed by Evidence Based Medicine methods, which are not devoid of the influence of medical fashion: the medical community is more prone to accept fashionable statements compared to non-fashionable or old-fashioned statements(AU)
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Fotocópia
Id: 17166
Autor: Jiménez-Timon, A; Rodríguez Trabado, A; Hernández Arbeiza, FJ; Porcel Carreño, S; Rodríguez Martín, E; Cobo López, R; Agustín Herrero, J.
Título: Rinomanometría anterior como test diagnóstico en alergia ocupacional por liliáceas / No disponible
Fonte: Allergol. immunopatol;30(5):295-299, sept. 2002.
Idioma: Es.
Resumo: La familia de las liliáceas ha sido implicada en el desarrollo de rinoconjuntivitis y asma bronquial ocupacional. Presentamos un paciente con síntomas cuando manipulaba especias, incluyendo ajo y cebolla en polvo. Material y métodos: Se realizan test cutáneos con inhalantes, especias comerciales, liliáceas en fresco y con extractos de polvo de especias. Se determinó IgE especifica (CAP-Pharmacía) y se realizó Immunoblotting con ajo.Se llevo a cabo control de pico flujo (PEF) en la zona de manipulación de especias y en la zona de transporte del producto envasado. Se realizó test de provocación nasal con el ajo y la cebolla y se midió la obstrucción nasal mediante rinomanometría anterior activa (RAA). Resultados: Los test cutáneos fueron positivos con el polvo de ajo, cebolla, y con las liliáceas en fresco. La IgE específica fue positiva para ajo y cebolla. El immunoblotting mostró dos bandas de fuerte intensidad correspondiente a 14 y 40 KD con el extracto de ajo. Se objetivó un aumento de la resistencia nasal superior al 100 per cent con ambos extractos (AU)

The Liliacea family has been implicated as a cause of occupational rhinoconjunctivities and bronchial asthma. We report a patient who presented symptoms when he manipulated spices including garlic and onion dusts. Nasal challenge test with active anterior rhinomanometry was used for the diagnosis. Material and methods: Skin-prick tests with common inhalants, commercial spices, fresh Liliaceae and powdered spices diluted in saline solution (10 mg/ml) were performed. Immunoblot and specific IgE (CAP-Pharmacia) were determined. Control peak expiratory flow was monitored during a period at work in an area where spices were manipulated and in an area where they were transported. Nasal challenge test with garlic and onion powder was performed. The resulting nasal obstruction was measured as nasal airway resistance and was determined by rhinomanometry. Results: Skin-prick tests were positive for onion, garlic powder and fresh Liliacea. Specific IgE were positive for garlic and onion. IgE immunoblotting showed very strong bands at 14 and 40 kD with garlic extract. Nasal challenge showed an increase in inspiratory nasal resistance which was higher than 100 % of the basal value for both onion extract and garlic (AU)
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Id: 8582
Autor: Arena, A; Cislaghi, C; Falagiani, P.
Título: Anaphylactic reaction to the ingestion of raw onion. A case report
Fonte: Allergol. immunopatol;28(5):287-289, sept. 2000.
Idioma: En.
Resumo: A case of severe systemic reactions (intense itching, urticaria, confusion, blurred vision, transient loss of consciousness, sweating, tachycardia) after ingestion of raw or lightly-cooked onion is described. The patient, a 44-year-old woman, had no troubles with well-cooked onions. Differently from the cases of sensitivity to onion described in literature, this patient was monosensitized, being skin tests negative to pollens, inhalants and other foods. The patient had 3.7 kU/L of onion-specific segum IgE, as determined by REAST. The density of onion-specific IgE (calculated as percent ratio to total IgE) was 30.8%. The reactivity of patient's serum IgE towards thermolabile and thermostable components has been tested with unheated and heated (30' at 100 ºC) onion extracts bound to polystyrene beads and tested in the RAST system. Unheated extract resulted positive in class 2, heated extract negative, demonstrating that this patients, differently from similar clinical cases described in literature, had IgE antibodies recognizing just thermolabile onion fraction. This is the first case described in literature of a monosensitization to the thermolabile component of onion, negative also to related foods (Liliacee) and characterized by severe systemic reactions. The importance of specific-IgE density (%) rather their absolute amount (kU/L) as parameter predictive for the clinical severity of allergic reactions is discussed (AU)

Historial: se describe un caso de graves reacciones sistémicas (picazón intensa, urticaria, confusión, vista borrosa, pérdida transitoria de la conciencia, transpira ción, taquicardia) como consecuencia de la ingestión de cebollas poco cocidas o crudas. El paciente, de sexo femenino y de 44 años de edad, no había experimentado trastorno al ingerir cebollas bien cocidas. Respecto a los casos de sensibilidad hacia la cebolla descritos en la literatura, esta paciente ha sido monosensibilizada, resultando negativa la prueba cutánea a los pólenes y otros inhalantes y alimentos.Métodos y resultados: en el suero de la paciente se detectó IgE específico frente a cebolla, mediante REAST, con un valor de 3,7 kU/L.La densidad de la IgE específica de la cebolla (calculado como razón porcentual del total de la IgE) ha sido 30,8 por ciento. La reactividad del suero de IgE del paciente hacia los componentes termolábiles y termoestables ha sido comprobada con extractos de cebolla calentados y no calentados (por 30 min a 100 ºC) en perlas de poliestirol y probados con el sistema RAST.El extracto no calentado ha resultado positivo de clase 2 mientras que el extracto calentado dio negativo, lo que demuestra que estos pacientes, al contrario de casos clínicos similares descritos en la literatura, presentaban anticuerpos de la IgE que reconocían solamente la fracción termolábil de la cebolla.Conclusiones: este es el primer caso descrito en la literatura de monosensibilización al componente termolábil de la cebolla, negativo también en alimentos que pertenecen a la familia de las Liliáceas y caracterizado por graves reacciones sistémicas. La importancia de la densidad de la IgE específica ( por ciento) respecto a la cantidad absoluta (kU/L), como parámetro que prevé la gravedad clínica de las reacciones alérgicas, resulta controvertida. (AU)
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