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Fotocópia
Id: 155862
Autor: Armentia, A; Pineda, F; Martin Armentia, B; Ramos, C; Gil Martin, FJ; Palacios, R.
Título: Endophthalmitis related to lemon allergy in a heroin addict
Fonte: Allergol. immunopatol;44(5):472-474, sept.-oct. 2016. ilus.
Idioma: en.
Resumo: Background: Heroin and its contaminants may be an important source of allergens in young people. We present a case of severe endophthalmitis in a patient that also suffered from anaphylactoid symptoms (hypotension, urticaria, glottic oedema) whenever he ingested lemon. Methods: Prick tests with a battery of 42 aeroallergens including fruits and citrus fruits (orange, mandarin, grapefruit and lemon) and specific IgE to these allergens were carried out. Immunodetection was performed using the patient's serum and the following allergens: lemon,Candida, Aspergillus, Penicillium and Alternaria recombinant Alt 1 (Laboratories Diater). Results: Skin tests were negative or Candida, Penicillium, Aspergillus and Cladosporium (ALK-Spain) as were specific IgE antibodies for CAP (Thermofisher, Sweden) and positive only for lemon and, doubtfully, to Candida. Specific IgE tests to pollen, arthropods, fungi, dander and foods were positive only for lemon (0.49kU/L). Serological study of fungi ruled out fungal infection at that time. The immunodetection showed that the patient's serum recognised a protein of approximately 25kDa of lemon peel, one of approximately 12û13kDa of Penicillium, and perfectly recognised Alt a 1. Conclusions: Lemon surface can be contaminated by Candida and other fungi. In heroin addicts with positive skin tests for lemon, the possibility of these serious complications should be taken into account (AU)

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  2 / 13 IBECS  
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Id: 141140
Autor: Montes-Borrego, Miguel; Jiménez-Díaz, Rafael M; Landa, Blanca B; Lopes, Joao RS.
Título: Combined use of a new SNP-based assay and multilocus SSR markers to assess genetic diversity of Xylella fastidiosa subsp. pauca infecting citrus and coffee plants
Fonte: Int. microbiol;18(1):13-24, mar. 2015. ilus, tab.
Idioma: en.
Resumo: Two haplotypes of Xylella fastidiosa subsp. pauca (Xfp) that correlated with their host of origin were identified in a collection of 90 isolates infecting citrus and coffee plants in Brazil, based on a single-nucleotide polymorphism in the gyrB sequence. A new single-nucleotide primer extension (SNuPE) protocol was designed for rapid identification of Xfp according to the host source. The protocol proved to be robust for the prediction of the Xfp host source in blind tests using DNA from cultures of the bacterium, infected plants, and insect vectors allowed to feed on Xfp-infected citrus plants. AMOVA and STRUCTURE analyses of microsatellite data separated most Xfp populations on the basis of their host source, indicating that they were genetically distinct. The combined use of the SNaPshot protocol and three previously developed multilocus SSR markers showed that two haplotypes and distinct isolates of Xfp infect citrus and coffee in Brazil and that multiple, genetically different isolates can be present in a single orchard or infect a single tree. This combined approach will be very useful in studies of the epidemiology of Xfp-induced diseases, host specificity of bacterial genotypes, the occurrence of Xfp host jumping, vector feeding habits, etc., in economically important cultivated plants or weed host reservoirs of Xfp in Brazil and elsewhere (AU)

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  3 / 13 IBECS  
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Id: 125879
Autor: Martins, Ana Paula; Nogueira, María Teresa; Costa, Maria do Ceu; Salgueiro, Ligia.
Título: Requisitos de calidad de los aceites esenciales: importancia de las monografías de la Farmacopea Europea y de las normas ISO / Quality requirements for essential oils: importance of the monographs of the European Pharmacopoeia and ISO standards
Fonte: Rev. fitoter;11(2):131-146, dic. 2011. ilus, tab.
Idioma: es.
Resumo: Los aceites esenciales son productos naturales utilizados por diferentes industrias, entre las que destacan la alimentaria y la farmacéutica. Debido a la variabilidad inherente a los productos naturales y a los crecientes problemas de adulteraciones, el presente artículo tiene como objetivo promover y llamar la atención sobre la importancia de las normas internacionales existentes, especialmente las monografías de la Farmacopea Europea y las normas ISO, haciendo simultáneamente una comparación de los principales requisitos de estas directrices. Sólo el cumplimiento de estas normas puede garantizar que los aceites esenciales utilizados para diferentes fines tienen la calidad deseable para el propósito al que se destinan y que no se produzcan problemas de seguridad (AU)

Essential oils are natural products used by different industries, among which stand out pharmaceutical and food industries. Due to the variability inherent to all natural products and also to the growing problems of adulteration, this article aims to promote and draw attention to the importance of existing international standards, including the monographs of the European Pharmacopoeia and ISO standards, while making a comparison of the main requirements of these guidelines. Only the fulfillment of these standards can ensure that the essential oils used for different purposes have the desirable quality for the intended use and do not cause safety issues (AU)
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  4 / 13 IBECS  
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Texto completo SciELO Espanha
Id: 124825
Autor: Martín Martín, M; López, M; Cerezo, L.
Título: Xerostomía postradioterapia. Eficacia de tratamientos tópicos basados en aceite de oliva, betaína y xilitol / Xerostomia post-radiation therapy. Efficacy of topical treatments based on olive oil, betaine and xylitol
Fonte: Av. odontoestomatol;30(3):161-170, mayo-jun. 2014. ilus, mapas.
Idioma: es.
Resumo: La xerostomía es la complicación más frecuente en los pacientes que reciben radioterapia para el cáncer oral. La reducción en la tasa de flujo salival y una disminución de su pH están directamente relacionado con un cambio en la composición de la saliva y el desplazamiento de la microflora oral hacia especies bacterianas cariogénicas. Por otro lado sabemos que la xerostomía se asocia a dificultad para el habla, la masticación, la deglución, cambios en el sabor, caries dentales, sensación de ardor, infecciones microbianas y un deterioro de la calidad de vida. El manejo de la xerostomía incluye la prevención, la estimulación y el tratamiento sintomático. La prevención no siempre es posible a pesar de que con radioterapia de intensidad modulada (IMRT), se puede administrar dosis más bajas de radiación a las glándulas parótidas. Los fármacos estimuladores, como los agonistas colinérgicos, han demostrado mejorar la xerostomía, sin embargo tienen efectos secundarios y están contraindicados en algunas patologías. Hoy disponemos de una gran variedad de productos tópicos para el alivio de los síntomas de la boca seca, como la goma de mascar, pastillas sin azúcar, sustitutos salivales, cremas hidratantes o pastas dentales. Un trabajo previo nos indica que el uso diario de productos de boca seca tópicos que contienen aceite de oliva, betaína y xilitol es seguro y eficaz en el alivio de los síntomas de xerostomía en pacientes con xerostomía inducida por fármacos. En este trabajo se revisa la eficacia de las diversas opciones de tratamiento para la hiposalivación inducida por la radiación y presentamos nuestros resultados con el uso de productos tópicos específicos en estos pacientes (AU)

Xerostomia is the most frequent complication among patients who receive radiotherapy for oral cancers. A reduction in salivary flow rate and decrease of its pH is paralleled with a change in saliva competence and shifting of oral microflora to cariogenic bacterial spices. Therefore difficulties in speech, mastication, swallowing, changes in taste, dental caries, burning sensation, microbial infections and a compromised quality of life are associated with the presence of xerostomia. Studies have led to three therapeutic approach for xerostomia treatment: prevention, stimulation and symptomatic treatment. Prevention it is not always possible, although intensity modulated radiation therapy (IMRT) technique, gives the ability to delivering lower doses of radiation to parotid glands. Stimulation agents as cholinergic agonist have all demonstrated some ability to improve xerostomia, however have side effects and are contraindicated for certain medical disorders. There are a huge variety of products for relief dry mouth symptoms as Chewing gum, sugarfree lozenges, salivary substitutes and moisturizers, toothpastes. A previous study report that the daily use of topical dry mouth products containing olive oil, betaine and xilitol is safe and effective in relieving symptoms of xerostomia in a population with polypharmacy-induced xerostomia. The objective of this study is to review efficacy of various treatment options for radiation-induced hyposalivation and present our results with the use of specific topical products in this patients (AU)
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  5 / 13 IBECS  
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Id: 122609
Autor: Mercader, Josep; Wanecq , Estelle; Carpéné , Christian; Chen , Jian.
Título: Isopropylnorsynephrine is a stronger lipolytic agent in human adipocytes than synephrine and other amines present in Citrus aurantium
Fonte: J. physiol. biochem;67(3):443-452, sept. 2011. ilus.
Idioma: en.
Resumo: No disponible

The weight loss observed in consumers of extracts of Citrus aurantium (bitter orange) has been tentatively attributed to the lipolytic and thermogenic effects of the alkaloids abundant in the unripe fruit. Synephrine, octopamine, tyramine, and other alkaloids have been repeatedly identified and quantified in Citrus members of the Rutaceae family or in their extracts incorporated in dietary supplements for weight management. However, there are only scarce reports on their lipolytic action. This study aimed at comparing the acute lipolytic activity of synephrine, octopamine, tyramine, andN-methyltyramine in rat and human adipocytes. Maximal respo (..) (AU)
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  6 / 13 IBECS  
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Id: 121972
Autor: Soudani, Nejla; Amara, Ibtissem Ben; Troudi, Afef; Zeghal, Najiba; Rafrafi, Moez; Ben Salah, Hichem; Hakim, Ahmed; Zeghal, Khaled Mounir; Boudawara, Tahia.
Título: Oxidative stress-related lung dysfunction by chromium(VI): alleviation by Citrus aurantium L
Fonte: J. physiol. biochem;69(2):239-253, jun. 2013.
Idioma: en.
Resumo: Chromium(VI), a very strong oxidant, causes high cytotoxicity through oxidative stress in tissue systems. Our study investigated the potential ability of ethanolic Citrus aurantium L., family Rutaceae extract, used as a nutritional supplement, to alleviate lung oxidative damage induced by Cr(VI). A high-performance liquid chromatography coupled with a mass spectrometer method was developed to separate and identify flavonoids in C. aurantium L. Six flavonoids were identified, as (1) poncirin, (2) naringin, (3) naringenin, (4) quercetin, (5) isosinensetin, and (6) tetramethyl-o-isoscutellarein. Adult Wistar rats, used in this study, were divided into six groups of six animals each: group I served as controls which received standard diet, group II received via drinking water K2Cr2O7 alone (700 ppm), groups III and IV were pretreated for 10 days with ethanol extract of C. aurantium L. at doses of 100 and 300 mg/kg body weight/day, respectively, and then K2Cr2O7 was administrated during 3 weeks, and groups V and VI received during 10 days only C. aurantium L. ethanol extract at doses of 100 and 300 mg/kg/day, respectively. Ethanol extract of C. aurantium L. was administered orally. Rats exposed to Cr(VI) showed in lung an increase in malondialdehyde and protein carbonyl levels and a decrease in sulflydryl content, glutathione, nonprotein thiol, and vitamins C and E levels. Decreases in enzyme activities such as in Na+K+ ATPase, catalase, glutathione peroxidase, and superoxide dismutase were noted. Pretreatment with C. aurantium L. of chromium-treated rats ameliorated all biochemical parameters. Lung histological studies confirmed the biochemical parameters and the beneficial role of C. aurantium L (AU)
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  7 / 13 IBECS  
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Id: 91059
Autor: Costa Carvalho, Daniel Diego; Alves, Eduardo; Barbosa Camargos, Renato; Ferreira Oliveira, Denilson; Soares Scolforo, José Roberto; Carvalho, Douglas Antônio de; Sâmia Batista, Tereza Raquel.
Título: Extractos vegetales para el control de Alternaria alternata en frutos de tangor Murcott / Plant extracts to control Alternaria alternata in Murcott tangor fruits
Fonte: Rev. iberoam. micol;28(4):173-178, oct.-dic. 2011.
Idioma: es.
Resumo: Antecedentes. Alternaria alternata causa la mancha marrón en muchas mandarinas y en sus híbridos en todo el mundo. Extractos de plantas proporcionan un método alternativo para controlar esta enfermedad cuyo control se basa en fungicidas químicos. Objetivos. Identificar las especies de plantas con propiedades antifúngicas contra A. alternata, el agente causal de la mancha marrón. Métodos. Extractos de plantas preparados a partir de hojas, corteza, flores y tallos recogidos de 105 especies de plantas en el Estado de Minas Gerais, Brasil, fueron utilizados para estudiar su actividad contra el hongo A. alternata in vitro e in vivo. Resultados. El extracto más prometedor se obtuvo de Anadenanthera colubrina, que redujo la enfermedad en las frutas de tangor Murcott a los niveles obtenidos con fungicidas comerciales. Artemisia annua, Cariniana estrelensis, Ficus carica y Ruta graveolens presentaron moderada actividad antifúngica in vitro, pero no se observaron efectos sobre la enfermedad cuando los extractos fueron aplicados a los frutos inoculados con el hongo. Además, A. colubrina fue el más activo contra A. alternata en el ensayo in vitro. Conclusiones. Los resultados obtenidos en los ensayos in vitro e in vivo sugieren que el método de crecimiento de hongos, que utiliza placas de 96 pozos de polipropileno, parece apropiado para la selección de especies potenciales para testar nuevos métodos de control de la mancha marrón(AU)

Background. Alternaria alternata causes the Alternaria brown spot disease (ABS) in many tangerines and their hybrids worldwide. Plant extracts offer an alternative method for controlling this disease, which control is based on chemical fungicides. Aims. To identify plant species with antifungal properties against A. alternata, the causal agent of the ABS. Methods. Plant extracts prepared from leaves, barks, flowers, and stalks collected from 105 plant species in the State of Minas Gerais, Brazil, were tested for activity against the fungus A. alternata in vitro and in vivo. Results. The most promising extract was obtained from Anadenanthera colubrina, which reduced the disease on Murcott tangor fruits to levels obtained with commercial fungicides. Artemisia annua, Cariniana estrelensis, Ficus carica, and Ruta graveolens presented moderate in vitro antifungal activity, but no effects were observed on the disease when the extracts were applied to fruits inoculated with the fungus. Besides, A. colubrina was the most active extract against A. alternata in the in vitro assay. Conclusions. The results obtained in the in vitro and in vivo assays suggested that the fungal growth test, which uses 96-well polypropylene plates, seems to be appropriate for selecting potential plant species for testing new methods to control ABS(AU)
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  8 / 13 IBECS  
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Texto completo SciELO Espanha
Id: 86389
Autor: Ayechu, A; Durá, T.
Título: Calidad de los hábitos alimentarios (adherencia a la dieta mediterránea) en los alumnos de educación secundaria obligatoria / Quality of dietary habits (adherence to a mediterranean diet) in pupils of compulsory secondary education
Fonte: An. sist. sanit. Navar;33(1):35-42, ene.-abr. 2010. tab.
Idioma: es.
Resumo: Fundamento. La dieta mediterránea está consideradacomo un prototipo de dieta saludable. La modernizaciónde la sociedad implica cambios culturales y/o sociológicosque afectan a los hábitos y preferencias alimentarias.El objetivo de este trabajo es determinar elíndice de calidad de los hábitos alimentarios entre losalumnos de educación secundaria obligatoria (ESO).Material y métodos. Distribución de un cuestionario de16 preguntas (test kidmed) a una muestra aleatoria de1.956 alumnos de ESO (966 varones y 990 mujeres). Lapuntuación final o índice kidmed (de 0 a 12) indica si laadherencia a la dieta mediterránea es baja (de 0 a 3),media (de 4 a 7) o alta (de 8 a 12).Resultados. El 6,7% de los alumnos de ESO tenían uníndice kidmed bajo, el 50,4% medio y el 42,9% alto, sinque existieran diferencias significativas entre ambossexos. El índice kidmed disminuía progresivamentecon la edad (p<0,05). A los 13 años (1º ESO) el 49,5%tenían una puntuación óptima del índice kidmed, mientrasque a los 16 años (4º ESO) esta puntuación apenasla alcanzaba un 37,2%. Entre los alumnos de 1º y 4º deESO existían diferencias significativas (p<0,05) respectoal consumo de frutas, pescados, frutos secos, bolleríaindustrial y dulces; así como en la falta de regularidaddel desayuno y la frecuentación de hamburgueserías.Conclusiones. Al terminar la ESO el 62,8% de los alumnospresentaban una adherencia media-baja a la dieta mediterránea.Las normas dietéticas aplicables a estos adolescentesconsistirían en incrementar el consumo de frutas,verduras y hortalizas, frutos secos, pastas y arroz, yoguresy quesos, legumbres y pescados, así como disminuirla ingesta de bollería industrial y dulces y la frecuentaciónde hamburgueserías; siendo importante el desayuno diarioy el consumo de aceite de oliva como grasa culinaria.Sería conveniente desarrollar programas de educaciónnutricional durante la enseñanza obligatoria(AU)

Background. The Mediterranean diet is considered tobe a prototype of a healthy diet. The modernization ofsociety implies sociological and cultural changes thataffect feeding preferences and habits. The aim of this paperis to determine the quality index of the dietary habitsin pupils of compulsory secondary education (CSE).Material and methods. By distributing a 16 item questionnaire(kidmed test) to a random sample of 1,956 pupilsof CSE (966 males and 990 females). The final scoreor kidmed index (range 0-12) indicates whether the degreeof adherence to the Mediterranean diet is low (0-3),medium (4-7) or high (8-12).Results. A low kidmed index value was registered in 6.7%of the pupils of CSE, whereas medium values correspondedto 50.4% and low values to 42.9%, showing nosignificant statistical differences between the sexes. Thekidmed index decreases progressively with age (p<0.05).At age 13 (first year of CSE), 49.5% of the pupils had anoptimal score on the kidmed index, whereas at 16 (fourthyear of CSE), this score reached 37.2%. There were statisticaldifferences (p<0.05) regarding consumption of fruit,fish, nuts and dried foods, sweets and factory producedbaked foodstuffs; pupils also frequently went withoutbreakfast and ate at fast food restaurants.Conclusions. By the end of CSE, 62.8% of pupils showeda low-medium degree of adherence to the Mediterraneandiet. Applicable food advice for these adolescentswould be to increase consumption of fruit, vegetables,nuts, pasta and rice, yogurt and cheese, pulses and fish;and to reduce consumption of factory produced bakedfoodstuffs and sweets and to eat less at fast food restaurants;besides insisting on the importance of dailybreakfast and the use olive oil for cooking. In addition,it would be convenient to develop nutrition educationprograms during compulsory education(AU)
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Texto completo SciELO Espanha
Id: 044347
Autor: Oussama, Abdelkhalek; Touhami, Mohamed; Mbarki, Mohamed.
Título: In vitro and in vivo study of effect of lemon juice on urinary lithogenesis
Fonte: Arch. esp. urol. (Ed. impr.);58(10):1087-1092, dic. 2005. ilus.
Idioma: En.
Resumo: OBJETIVOS: La variedad de resultados experimentales obtenidos en el estudio del efecto del jugo de cítricos en la litogénesis urinaria nos llevó a su efecto in vitro e in vivo. El estudio in vitro se basa en un método de turbidometría de la cristalización de oxalato cálcico. En vivo, estudiamos el efecto del consumo de jugo de limón en la bioquímica urinaria y evaluamos el efecto sobre la cristalización de oxalato cálcico en orina natural.MÉTODOS: La adición de una solución de oxalato y calcio induce la formación de cristales. La densidad óptica se mide en un sistema cerrado en condiciones fisiológicas. Los efectos de los diferentes jugos de limón fueron evaluados añadiendo 50 ml. Un voluntario sano, sin historia previa de cálculos renales participó en el estudiomediante la ingestión de jugo de limón. Se determinaronel pH y las concentraciones de oxalato, calcio y citrato antes y después de la ingestión, analizándose la orina fresca al microscopio.RESULTADOS Y CONCLUSIONES: En la orina sintética,el porcentaje de inhibición de la cristalización de oxalato cálcico aumentó gradualmente con la concentraciónde jugo de limón. En la orina natural, notamos que las cinéticas de cristalización del oxalato cálcico antes y después de la ingestión del jugo de limón son comparables. In vivo, después de la ingestión se apreciaun ligero aumento del pH urinario medio (desde 6.7± 0.1 a 6.9 ± 0.1). De hecho, las concentraciones de oxalato cálcico y la excreción de citrato aumentaron durante este periodo el 33.41%, 6.85% y 3.53% respectivamente.Este aumento de la excreción de oxalato se explicaría probablemente por la conversión del ácidoascórbico exógeno contenido en el jugo de limón. Estos resultados muestran que el jugo de limón presenta un importante efecto inhibitorio in vitro. La ingestión del jugo de limón parece disipar el efecto de gran cantidad de citratos, un aumento de la excreción de oxalato. La presencia de estos dos elementos simultáneamente, citratoy oxalato, compensa sus efectos opuestos

OBJECTIVES: The diversity of experimental results obtained in the study of the effect of citrus juice on urinary lithogenicity moved us to study the effect of these substances in vitro and in-vivo. The in-vitro study is based on the turbidimetric method on calcium oxalate crystallization. In vivo, we studied the effect of lemon juice consumption on urinary chemistry and we tested it on calcium oxalate crystallization in natural urine. METHODS: The formation of crystals is induced by the addition of the oxalate and calcium solution. Optical density (OD) is measured in a closed system at physiological conditions. The effects of the various juices of lemon, was evaluated by the addition of 50 ml of juice. A male volunteer with no history of kidney stone participated in this study, by lemon juice ingestion. The pH, concentration of oxalate, calcium and citrate were determined before and after ingestion and urine was freshly analyzed by microscopy. RESULTS AND CONCLUSIONS: In synthetic urine, the inhibition rate of calcium oxalate crystallization increases gradually with the lemon juice concentration. In natural urine, we noted that the kinetics of crystallization of calcium oxalate, before and after ingestion of lemon juice, are comparable. In vivo, after ingestion, a small increase in mean urinary pH (from 6.7 ± 0.1 to 6.9 ± 0.1) was noted. Indeed, oxalate calcium means and citrate excretion increased during this period with 33. 41%, 6. 85 % and 3. 53% respectively. This increase in the oxalate excretion is probably explained by the conversion of the exogenous ascorbic acid contained in the lemon juice. These results show that the lemon juice presents an important inhibitory effect in vitro. The ingestion of the lemon juice seems to dissipate a effect of great quantity of citrates which in turn increases the excretion of oxalates. The presence of these two elements simultaneously: citrate and oxalate compensate for their opposite effect
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  10 / 13 IBECS  
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Id: 043862
Autor: Barbany Cairó, Joan R; Javierre Garcé, Casimiro.
Título: Suplementación en vitamina C y rendimiento deportivo (I) / Vitamin C supplementation and sport performance (I)
Fonte: Arch. med. deporte;23(111):49-59, ene.-feb. 2006. ilus, tab.
Idioma: Es.
Resumo: No disponible

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