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Fotocópia
Id: 181885
Autor: Espinosa-Barberi, Glenda; Reyes Rodríguez, Miguel Ángel; Francisco Hernández, Félix.
Título: Enfermedad de Vogt-Koyanagi-Harada: estudio de 14 casos / Vogt-Koyanagi-Harada disease: study of 14 cases
Fonte: Med. clín (Ed. impr.);152(4):159-160, feb. 2019. tab.
Idioma: es.
Resumo: No disponible
Responsável: ES1.1
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Texto completo
Id: 181079
Autor: Palmerín-Donoso, Alba; Tejero-Mas, Manuel; Buitrago-Ramírez, Francisco.
Título: Herpes zóster oftálmico / Herpes zoster ophthalmicus
Fonte: Aten. prim. (Barc., Ed. impr.);51(2):123-124, feb. 2019. ilus.
Idioma: es.
Resumo: No disponible
Responsável: ES1.1
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Texto completo SciELO Espanha
Id: 180839
Autor: Molina-Aragonés, Josep María; Lemonche-Aguilera, Consol; Sánchez-San Cirilo, Silvia; López-Pérez, Cristóbal.
Título: Cuestionario CVSS17 y vigilancia de la salud de trabajadores profesionalmente expuestos a pantallas de visualización / CVSS17 Questionnaire and Health Monitoring of Workers Professionally Exposed to Display Screens
Fonte: Med. segur. trab;64(253):329-344, oct.-dic. 2018. graf, tab.
Idioma: es.
Resumo: Introducción: Según la Encuesta Europea de Condiciones de...

Introduction: According to the European Working Conditions Survey, 37 % of workers are using devices with display screens almost the whole working day, and 20 % of workers use them for at least a quarter of its working day. The health surveillance of these workers is still based on the specific protocol of 1999. From then on, there have been remarkable changes in the design and performance of the work equipments. Many workers from different working areas have introduced these technologies to their common tasks and non-work activities. Likewise, display screens, in different sizes and formats, have also been incorporated into the daily life of many people. In view of these changes, it is necessary to update this health surveillance protocol in order to optimize the prevention of the exposed workers. Aim: The aim of our work is not only to value the behavior of the CVSS17 questionnaire assessing the visual and ocular system through a specific physical examination, but to determine its usefulness as a screening element in order to monitor the health of the workers professionally exposed to display screens. Method: Cross-sectional study carried out between September 2016 and February 2017, with the results of the health examinations of workers professionally exposed to display screens in the offices of the Institut Català de la Salut. Initially, the workers completed the CVSS17 questionnaire, developed as a scale to measure the computer-related ocular and visual symptoms associated with the use of PVD. Afterwards, the health surveillance took place. This involved different maneuvers and diagnostic tests in the oculo-visual sphere. A new variable was built up with these data; we called it "overall visual disturbance", used as a reference test (gold standard) to calculate the validity of the questionnaire and the construction of ROC curves. Results: A total of 184 individuals answered the questionnaire. 150 (81.52%) underwent voluntarily the health examination. Their data were included in the study. 102 of them were women (68.0%) and 48 men (32.0%), with an average age of 49.3 years and a standard deviation of 8.5 years. The results of the CVSS17 questionnaire showed symptom levels (SL) from 1 to 5 respectively of 37 (24.7%), 42 (28.0%), 41 (27.3%), 25 (16.7%) and 5 (3.3%) individuals. Symptomatology Level grade 6 was not obtained. When performing the ocular exploration, 6 individuals (4.0%) showed alteration of the near visual acuity, 34 (22.7%) showed an alteration in the main gaze position, 13 (8.7%) showed an alteration of the macular overload test, 15 (10.0%) showed an alteration of the near conversion point, 13 (8.7%) an alteration of the Amsler test, 50 (33.3%) had altered the Schirmer test and 5 (3.3%) presented alteration in the color vision. Overall, 87 individuals (58.0 %) showed disturbances of at least one of the visual-eye examination tests. The ROC curve adjustment from the "overall visual disturbance" variable did not show significant differences [Area under the curve of 0.47 (95% CI: 0.37-0.57, p = 0.51)], so that the probabilities of correctly classify a pair of individuals as one healthy and another pathological are minimal. Conclusions: No relationship has been found between the intensity of these symptoms and the specific ophthalmological clinical examination by using a questionnaire designed to measure the ocular and visual symptoms associated with the use of display screens. The presence of clinical alterations has been significantly related with the age of the individuals. Female gender has been associated with a higher manifestation of the oculo-visual syndrome symptoms. CVSS17 is a tool that can be used to characterize and monitor the ocular-visual symptoms related to the use of display screens. Used as a screening tool, this tool reaches a sensitivity of 0.838 while its specificity would be only 0.140
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Id: 180825
Autor: Domínguez-Serrano, FB; Molina-Solana, P; Infante-Cossío, M; Sala-Turrens, J; Seva-Silva, N; Rodríguez-de-la-Rúa-Franch, E.
Título: Oftalmología de urgencias. Un estudio epidemiológico: ¿se utilizan correctamente los recursos? / Ophthalmological emergencies. An epidemiological study: Are resources been used properly?
Fonte: Arch. Soc. Esp. Oftalmol;94(5):211-217, mayo 2019. tab, graf.
Idioma: es.
Resumo: Objetivo: Determinar la epidemiología de todas las visitas a urgencias oftalmológicas incluyendo todos los grupos de edad durante los años 2014 y 2015 en dos hospitales de tercer nivel. Métodos: Fueron incluidos todos los pacientes que acudieron a urgencias oftalmológicas desde el 1 de enero de 2014 al 31 de diciembre de 2015. Las variables estudiadas fueron el sexo, la edad, el lugar de procedencia, la hora de llegada, el día de la semana, el mes y el año de la visita, el diagnóstico, el lugar de derivación al alta, el nivel de prioridad y el tiempo total de asistencia. Las patologías fueron clasificadas según los códigos CIE-9, MC. Resultados: Se produjeron un total de 39.869 visitas a urgencias entre los años 2014 y 2015. Estas fueron más frecuentes en el sexo femenino, los lunes y en los meses de abril, mayo y junio. La edad media fue de 46,24 años. El 73,42% de las visitas se clasificaron como no urgentes. La patología más frecuente atendida fue la conjuntivitis (17,28%), seguida de queratitis (15,31%) y desprendimiento de vítreo posterior (5,37%). La celulitis orbitaria fue la patología que cursó con un mayor porcentaje de ingresos (23%). La mayoría de los pacientes fueron derivados al alta a su domicilio (94,85%). Conclusiones: Dado que la gran mayoría de patologías atendidas en urgencias son no urgentes, es conveniente el establecimiento de medidas para conseguir una asistencia más eficiente, orientada a la patología urgente y que no consuma recursos innecesarios

Objectives: To determine the prevalence of ophthalmological emergency visits to two tertiary hospital in all age groups during years 2014 and 2015. Methods: All patients who attended Ophthalmological Emergency Department from 1 January 2014 to 31 December 2015 were included in the study. The demographic variables studied were gender, age, place of origin, time of arrival, day of the week, month and year of the visit, the diagnosis, destination on discharge, total time of the visit and priority. Pathologies were categorised using codes from ICD-9, CM. Results: A total of 39,869 visits were made between 2014 and 2015. Emergency consultations were more frequent among women, on Mondays, and from April to June. The mean age of the patients was 46.24 years old, and 73.42% of visits were classified as non-emergencies. The most frequent pathology was conjunctivitis (17.28%), followed by keratitis (15.31%), and vitreous detachment (5.37%). The pathology that led to more hospital admissions was orbital cellulitis (23%). The majority of patients (94.85%) were sent to their place of residence after the visit. Conclusions: Given that the great majority of Ophthalmological Emergency visits are categorised as non-emergencies, measures need to be set up in order achieve a more effective care focused on emergency pathology without using unnecessary resources
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Id: 180667
Autor: Reyes-Bueno, José A; Rodríguez-Santos, Lucía; Serrano-Castro, Pedro J.
Título: Miastenia grave inducida por tratamiento con inhibidores del punto de control inmunológico: primer caso secundario a avelumab y revisión de casos previamente publicados / Myasthenia gravis induced by inmuno checkpoints inhibitors: first case report secondary to avelumab therapy and review of published cases
Fonte: Rev. neurol. (Ed. impr.);68(8):333-338, 16 abr., 2019. tab.
Idioma: es.
Resumo: Introducción. Los fármacos inhibidores del punto de control inmunológico han supuesto una revolución en el tratamiento de varios procesos neoplásicos en estadio avanzado. Sin embargo, se han descrito numerosas complicaciones neurológicas, entre las que se encuentran polineuropatías, crisis epilépticas, radiculitis y miastenia grave. Caso clínico. Varón de 65 años con adenocarcinoma de pulmón en estadio IV en tratamiento con avelumab que desarrolla una miastenia grave ocular seropositiva, con buena respuesta a la piridostigmina y retirada de la medicación. Conclusiones. El mecanismo exacto por el cual el avelumab induce una miastenia grave aún se desconoce, y probablemente existe un proceso fisiopatológico diferente al de la miastenia grave idiopática. Un dato importante es la variabilidad en cuanto al tiempo de aparición de la miastenia grave después de iniciar el tratamiento con inhibidores del punto de control inmunológico. Desde el punto de vista clínico, la mayoría de los casos descritos comenzó con una forma de miastenia grave generalizada con afectación bulbar que posteriormente desarrolló oftalmoparesia y ptosis palpebral fluctuante. Este caso, así como la revisión de la bibliografía, puede ser útil para alertar al neurólogo clínico sobre la posibilidad del desarrollo de cuadros inmunomediados de esta naturaleza inducidos por el tratamiento con avelumab en la práctica clínica y para orientar sus características clínicas, pronósticas y de tratamiento

Introduction. The inmuno checkpoints inhibitors are new revolutionary treatment for many neoplastic diseases in advanced stadium. There are described several types of neurological complications induced by nivolumab: polyneuropathy, seizures, radiculitis and myasthenia gravis disease. Case report. A 65 years old man with metastatic lung adenocarcinoma who presented myasthenia gravis disease induced by avelumab therapy with good response to treatment with pyridostigmine and withdrawal of avelumab. Conclusions. The exact mechanism by which this drug induces myasthenia gravis is still unknown and there is probably a different pathophysiological process to idiopathic myasthenia gravis. An important fact is the variability in the time of onset of myasthenia gravis after initiating treatment with inmuno checkpoints inhibitors. From the clinical point of view, most of the reported cases appeared with a generalized form of myasthenia gravis with bulbar involvement and later developed ophthalmoparesis and fluctuating palpebral ptosis. Our case as well as the review of the previous literature can be useful to alert the clinical neurologist about the possibility of the development of immune-mediated cases of this nature induced by the treatment with avelumab in clinical practice as well as to guide its clinical, prognostic and clinical characteristics and treatment
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Id: 180380
Autor: Ortiz-Morales, G; Domene-Hickman, J; Villarreal, A; Valdez-Garcia, JE.
Título: La práctica oftalmológica en México del siglo xviii / The practice of ophthalmology in Mexico in the 18th century
Fonte: Arch. Soc. Esp. Oftalmol;94(2):e17-e18, feb. 2019.
Idioma: es.
Resumo: No disponible
Responsável: ES1.1
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Id: 180379
Autor: Fernández Jacob, MC.
Título: Influencia de la monoftalmía de Edgar Degas en su obra pictórica / Influence of the monophthalmia of Edgar Degas in his pictorial work
Fonte: Arch. Soc. Esp. Oftalmol;94(2):e14-e16, feb. 2019. ilus.
Idioma: es.
Resumo: No disponible
Responsável: ES1.1
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Id: 180371
Autor: García de Oteyza, G; Betancourt, J; Benedetti Sandner, M; Vázquez-Romo, KA; Hernández-Ayuso, I; Ramos-Betancourt, N.
Título: Nevus compuesto inflamatorio juvenil: no es melanoma todo lo que parece / Inflammatory juvenile compound nevi: A melanoma is not all that it appears to be
Fonte: Arch. Soc. Esp. Oftalmol;94(2):90-94, feb. 2019. ilus.
Idioma: es.
Resumo: Niña de 11 años que acude por crecimiento rápido de lesión pigmentada en conjuntiva bulbar del ojo izquierdo. Debido a las características biomicroscópicas y ultrasónicas de la lesión se realizó una biopsia escisional con técnica "no touch" y criocoagulación en márgenes quirúrgicos. La anatomía patológica demostró la presencia de un nevus compuesto inflamatorio de conjuntiva. Los tumores melánicos de la conjuntiva son en su gran mayoría benignos. Sin embargo, el crecimiento acelerado de una lesión, la vascularización de la misma, los márgenes irregulares y la diferente coloración deben hacer pensar en una malignización. En tal caso, la biopsia escisional es obligatoria. A pesar de todas las características clínicas de malignidad, principalmente en jóvenes, puede tratarse de un nevus compuesto inflamatorio

An 11 year-old girl presented with a recent growth pigmented conjuntival lesion in the bulbar conjunctiva of left eye. Due to the the biomicroscopic and ultrasound findings, an excisional biopsy was performed on the lesion using the "no touch" technique, as well as cryo-coagulation of surgical margins. Histopathological examination revealed an inflammatory compound nevus. Melanotic conjunctival tumours are mostly benign. However, the recent growth of a lesion, its vascularisation, irregularities of the margins, and colour change must suggest it has turned malignant. In such case, excision of the lesion is mandatory. Despite all the clinical changes, especially in young patients, it can still be an inflammatory compound nevus
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Id: 180369
Autor: Zimmermann-Paiz, MA; Quezada-del Cid, NC; García-de la Riva, JC; Ordóñez-Rivas, AM.
Título: Melanoma amelanótico del iris en un niño hispano de 7 años con perforación del globo subclínica / Amelanotic iris melanoma in a 7 year-old hispanic boy with subclinical globe perforation
Fonte: Arch. Soc. Esp. Oftalmol;94(2):81-84, feb. 2019. ilus.
Idioma: es.
Resumo: Describimos el caso de un melanoma amelanótico del iris en un niño hispano de 7 años con perforación del globo subclínica. El melanoma uveal raramente ocurre en niños. La mayoría de los pacientes jóvenes afectados se presentan en la etapa de la pubertad, son caucásicos y con ojos claros. Debido a su rareza, estos tumores pueden no ser reconocidos o ser diagnosticados erróneamente. Destacamos el diagnóstico diferencial y las opciones terapéuticas

We report an unusual case of an amelanotic melanoma in a 7 year old hispanic child with subclinical globe perforation. Uveal melanoma rarely occurs in children. Young affected patients are mostly light-colored eye Caucasian adolescents. Since they are not common, these tumors are usually not recognized and misdiagnosed. Differential diagnoses and therapeutic options are outlined
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Id: 180368
Autor: Masson, W; Lobo, M; Huerín, M; Molinero, G; Lobo, L; Nogueira, JP.
Título: Inhibidores de la proproteína convertasa plasmática subtilisina kexina tipo 9 y riesgo de cataratas: revisión sistemática y metaanálisis / Plasma proprotein convertase subtilisin/kexin type 9 inhibitors and cataract risk: A systematic review and meta-analysis
Fonte: Arch. Soc. Esp. Oftalmol;94(2):75-80, feb. 2019. tab, graf.
Idioma: es.
Resumo: Antecedentes: El marcado descenso en los niveles de C-LDL producidos por los inhibidores de la proproteína convertasa plasmática subtilisina kexina tipo 9 (iPCSK9) podría asociarse con un mayor riesgo de cataratas. Métodos: Realizamos un metaanálisis que incluyó ensayos clínicos aleatorizados y controlados con iPCSK9, solos o combinados con otros fármacos hipolipidemiantes, que reportaron nuevos casos de cataratas, buscando en PubMed/Medline, bases de datos de EMBASE y Cochrane Clinical Trials. Se utilizó un modelo de efectos fijos y se realizó una metarregresión evaluando la relación entre el C-LDL intratratamiento y el riesgo de desarrollar cataratas. Resultados: Se tomaron en cuenta 5 estudios elegibles con iPCSK9 que incluyeron 83.492 pacientes para el análisis, refiriendo 531 nuevos casos de cataratas en el grupo con iPCSK9 frente a 532 en el grupo placebo. La terapia con iPCSK9 no se asoció con un mayor riesgo de presentar cataratas (OR: 0,96; IC 95%: 0,85-1,08; p = 0,86, I2: 0%]. Asimismo, no se encontró una asociación significativa entre la diferencia de C-LDL intratratamiento entre las ramas de los estudios y el riesgo de cataratas. Conclusión. En nuestro análisis, la utilización de iPCSK9 no se asoció con un mayor riesgo de cataratas

Background: The marked decrease in LDL-C levels produced by the inhibitors of the plasma proprotein convertase subtilisin/kexin type 9 (iPCSK9) could be associated with an increased risk of cataracts. Methods: A meta-analysis was performed that included randomised clinical trials controlled with iPCSK9, alone, or in combination with other lipid-lowering drugs, which reported new cases of cataracts, by searching PubMed/Medline, databases of EMBASE and Cochrane Clinical Trials. A fixed-effect model was used, and a meta-regression was carried out evaluating the relationship between intra-treatment LDL-C and the risk of developing cataracts. Results: Five eligible studies of iPCSK9 including 83,492 patients were taken into account for the analysis, and 531 new cases of cataracts in iPCSK9 group vs. 532 in placebo group were diagnosed. The iPCSK9 therapy was not associated with an increased risk of cataracts [OR: 0.96, 95% CI: 0.85-1.08; P = .86, I2: 0%]. Likewise, no significant association was found between on-treatment LDL-C levels, differences between study arms, and new cases of cataracts. Conclusion: In this analysis, the use of iPCSK9 was not associated with an increased risk of cataracts
Responsável: ES1.1
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