||Moro, Cedric; Harant, Isabelle; Badin, Pierre-Marie; Bourlier, Virginie; Langin, Dominique; De Glisezinski, Isabelle; Guilland, Jean-Claude; Patarca, François-Xavier.|
||Influence of lipolysis and fatty acid availability on fuel selection during exercise|
||J. physiol. biochem;70(2):583-591, jun. 2014.
The aim of the present study was to investigate the influence of substrate availability on fuel selection during exercise. Eight endurance-trained male cyclists performed 90-min exercise at 70 % of their maximal oxygen uptake in a cross-over design, either in rested condition (CON) or the day after 2-h exercise practised at 70 % of maximal oxygen uptake (EX). Subjects were given a sucrose load (0.75 g kg−1 body weight) 45 min after the beginning of the 90-min exercise test. Lipolysis was measured in subcutaneous abdominal adipose tissue (SCAT) by microdialysis and substrate oxidation by indirect calorimetry. Lipid oxidation increased during exercise and tended to decrease during sucrose ingestion in both conditions. Lipid oxidation was higher during the whole experimental period in the EX group (p = 0.004). Interestingly, fuel selection, assessed by the change in respiratory exchange ratio (RER), was increased in the EX session (p = 0.002) (..) (AU)