Database : LILACS
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Id: biblio-2442
Author: Guedes, Laura Vilar; Oliveira, Arthur Ivan Nobre; Guedes, Ana Luiza Vilar; Soares, Sandra Regina Castro; Sipahi, Aytan Miranda.
Title: Tripla infecção com HTLV-1, leishmaniose visceral e estrongiloidíase complicada por pancreatite aguda / Triple infection with HTLV-1, visceral leishmaniasis and strongyloidiasis complicated by acute pancreatitis
Source: GED gastroenterol. endosc. dig;35(3):96-100, jul.-set. 2016. ilustrado.
Language: pt.
Abstract: lntrodução: a estrongiloidíase tem grande importância médica devido à capacidade de o Strongyloides stercoralis completar seu ciclo de vida no homem e gerar a síndrome de hiperinfecção principalmente em imunocomprometidos. Devido à dificuldade em estruturar a resposta Th2, os pacientes infectados com o Vírus Linfotrópico de Células T Humanas Tipo 1 (HTLV-1) têm maior tendência a apresentar infecção maciça. A leishmaniose visceral, doença relevante em países em desenvolvimento, causa alterações imunológicas semelhantes, porém há poucos relatos de suscetibilidade específica ao Strongyloides stercoralis nos infectados por Leishmania sp. O presente trabalho tem objetivo de relatar um caso de coinfecção HTLV e calazar, que apresentou-se como pancreatite aguda e enteropatia perdedora de proteínas secundárias à estrongiloidíase maciça. Relato de caso: trata-se de um paciente de 34 anos com história de leishmaniose prévia que deu entrada no nosso Serviço com pancreatite aguda idiopática leve, além de história de diarreia crônica há um ano com anasarca e hipoalbuminemia associadas. Apresentou endoscopia digestiva alta com atrofia duodenal importante, tendo sido identificados Strongyloides stercoralis em biópsia, além de sorologia para HTLV positiva. Apresentou translocação bacteriana com sepse grave de foco abdominal, após início do tratamento com ivermectina, tendo posteriormente evoluído com melhora clínica importante e remissão dos sintomas. Fez investigação com punção de medula óssea, em que foram identificadas as formas amastigotas da leishmania. Discussão e conclusão: a presença de HLTV é um fator de risco para a síndrome de hiperinfecção por Strongyloides stercoralis, tendo predisposto o paciente às manifestações graves e raras descritas. A identificação de leishmania na medula óssea, entretanto, é um fator de risco ainda pouco conhecido para estrongiloidíase disseminada, porém com plausibilidade biológica por afetar o sistema imunológico do hospedeiro.(AU)

Introduction: strongyloidiasis has great medical importance because of the ability of the Strongyloides stercoralis to complete its life cycle in man and cause hyperinfection syndrome especially in immunocompromised hosts. Because of the difficulty in triggering The response, Human T-cell lymphotropic virus type 1 (HTLV-1) infected patients has susceptibility for massive infection. Visceral leishmaniasis, a relevant disease in developing countries, causes similar immunological changes, but there are few reports of specific susceptibility to Strongyloides stercoralis on infected by Leishmania sp. This study aimed to report a case of HTLV and kala azar coinfection, presenting as acute pancreatitis and protein losing enteropathy secondary to massive strongyloidiasis. Case report: a 34-year-old patient previously treated for leishmaniasis has presented at our service with idiopathic acute pancreatitis and chronic diarrhea for one year with anasarca and hypoalbuminemia. Upper endoscopy revealed duodenal atrophy in which biopsy identified Strongyloides stercoralis, and HLTV serology was positive. He presented with bacterial translocation and severe sepsis after first dose of ivermectin, but has clinical improvement and remission of symptoms afterwards. Bone marrow aspiration identified amastigote forms of Leishmania. Discussion and Conclusion: the presence of HLTV is a risk factor for Strongyloides stercoralis hyperinfection, and predisposed this patient to the serious and rare events described. The identification of Leishmania in bone marrow, however, is an poorly known risk factor for disseminated strongyloidiasis, but with biological plausibility because it affects the immune system of the host.(AU)
Responsable: BR9.1 - Biblioteca de Ciências da Saúde Profa. Susana Schimidt


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Id: biblio-1008259
Author: Santana, Adriana Trajano Torres de; Loureiro, Melina Bezerra.
Title: Síndrome de hiperinfecção e/ou disseminação por Strongyloides stercoralis em pacientes imunodeprimidos / Hyperinfection syndrome and/or dissemination by Strongyloides stercoralis in immunosuppressed patients
Source: Rev. bras. anal. clin;49(4):351-358, 2017.
Language: pt.
Abstract: A estrongiloidíase é causada principalmente pelo Strongyloides stercoralis, que afeta cerca de 30 a 100 milhões de pessoas em todo o mundo, sendo encontrada com maior frequência em países de clima tropical e subtropical. Usualmente, as infecções causadas por esse parasita são crônicas e assintomáticas, podendo persistir por décadas sem ser diagnosticada. Porém, em indivíduos imunodeprimidos, essa infecção pode se desenvolver para quadros mais graves como hiperinfecção e/ou disseminação, considerados como as formas que causam maior índice de mortalidade. Este trabalho relata, a partir de uma revisão da literatura, a associação do desenvolvimento da infecção causada pelo Strongyloides stercoralis em imunodeprimidos e a capacidade de evolução do parasita em indivíduos que fazem uso de corticosteroidoterapia, ressaltando a importância do diagnóstico precoce para evitar as formas graves da doença

The Strongyloidiasis is mainly caused by Strongyloides stercoralis which affects about 30 to 100 million people around the world, being found in greater frequency in countries with tropical and subtropical climates. Usually, the infections caused by this parasite are asymptomatic and chronic, that can persist for decades without being diagnosed. However, in immunocompromised individuals this infection can develop into more serious conditions such as hyperinfection and/or dissemination, considered the ways that cause the highest mortality rates. This paper reports the association of the development of infection caused by Strongyloides stercoralis in immunosuppressed and the development capacity of the parasite in individuals who make use of corticosteroidoterapia from a literature review, emphasizing the importance of early diagnosis to prevent severe forms of the disease
Responsable: BR408.1 - Biblioteca da Faculdade de Medicina - BFM


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Id: biblio-996667
Author: Venturi, Jakelline; do Livramento, Andréa; Nunes, Zeliana Souza; Botelho, Tatiani Karini Rensi.
Title: Strongyloides stercoralis hyperinfection in a renal transplant recipient
Source: Rev. patol. trop;48(1):61-66, abr. 2019.
Language: en.
Abstract: Strongyloidiasis is a worldwide intestinal infection produced by the nematode Strongyloides stercoralis. In this study, we report the case of a 47-year-old female patient who was submitted to renal transplant and an immunosuppression regimen. She was admitted to the emergency service with intense abdominal pain, evolving to an acute respiratory insufficiency, gram-negative bacteremia, refractory shock and death. S. stercoralis larvae were identified in the parasitological exam and bronchoalveolar lavage. This provides evidence for the importance of the early diagnosis of this neglected helminthiasis in transplanted patients undergoing immunosuppresive therapy
Responsable: BR15.1 - Biblioteca de Ciências Biomédicas


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Id: biblio-995495
Author: Córdoba, Claudia; Morales, Armando; Garzón, Julián; Ortiz, Fernando; Beltrán, Julián.
Title: Infección por Strongyloides stercoralis simulando un tumor intestinal: presentación de un caso / Infection Strongyloides Stercoralis Mimicking a Malignant Intestinal Tumor: Case Report
Source: Rev. colomb. radiol;24(3):3775-3779, 2013. graf, ILUS, TAB.
Language: es.
Abstract: Las enfermedades infecciosas pueden tener una presentación inicial similar a la de malignidad. Por ejemplo, la infección con la bacteria de la especie Actinomyces causa crecimiento de tejido infiltrativo similar a la observada en el cáncer de pulmón, tumores pélvicos o cáncer de colon; las enfermedades por protozoos, por ejemplo la Entamoeba histolytica, causa ulceración de la mucosa colónica con hallazgos similares al carcinoma; la infección viral por virus de Epstein-Barr puede causar proliferación de linfocitos que imita la leucemia, y la infección por hongos del tipo Cryptococcus gattii puede producir lesiones similares a las de cáncer de pulmón y cerebro. La familiaridad del radiólogo con las infecciones que se presentan con características similares a la malignidad es útil porque las infecciones inicialmente diagnosticadas como cáncer, manejadas y tratadas como tal, pueden llevar a intervenciones innecesarias, incluyendo procedimientos invasivos. El diagnóstico adecuado y precoz de las infecciones bacterianas o parasitarias que se presentan con imágenes similares a la malignidad será beneficioso para el paciente.

Infectious diseases can have an initial presentation similar to that of malignancy. For example, an infection with Actinomyces species bacteria causes infiltrative tissue growth similar to growth seen in lung cancer, pelvic tumor, or colon cancer; protozoal disease, e.g. with Entamoeba histolytica, can cause ulceration of the colonic mucosa similar in a manner similar to carcinoma. Viral infection with Epstein -Barr virus can cause proliferation of lymphocytes in a manner similar to leukemia, and fungal infection with Cryptococcus gattii can cause lesions similar to those present in lung and brain cancer. It is useful for the radiologist to be familiar with infections which present features similar to malignancy, because infections which are initially diagnosed as cancer, and are managed and treated as such, may lead to unnecessary interventions, including invasive procedures. Proper diagnosis and early bacterial or parasitic infections that occur with images similar to the malignancy will be beneficial to the patient.
Responsable: CO371.9


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Id: biblio-844989
Author: González Maestrey, Alba; Martínez Almeida, Emilio; Núñez Fernández, Fidel Ángel.
Title: Estrongiloidiasis crónica y uso prolongado de corticoides / Chronic strongyloidiasis and extended use of corticoids
Source: Rev. cuba. med. trop;68(3):255-261, sep.-dic. 2016. ilus.
Language: es.
Abstract: La infección causada por Strongyloides stercoralis puede permanecer asintomática o con síntomas ligeros en humanos por varios años. Sin embargo, algunos individuos inmunodeprimidos, entre ellos los pacientes tratados con esteroides por tiempo prolongado, pueden presentar hiperinfección con altas tasas de mortalidad. El objetivo es reportar por primera vez en Cuba el caso de una paciente con síntomas de estrongiloidiasis crónica asociada al uso de esteroides orales. Se trata de una paciente de 63 años, asmática con síntomas de estrongiloidiasis crónica y riesgo de hiperinfección por el uso de esteroides orales por tiempo prolongado. Se describen las manifestaciones clínicas y los análisis complementarios. Se discuten los factores predisponentes para la adquisición inicial y el desarrollo de la enfermedad. El laboratorio confirmó la presencia de larvas rabditoides de Strongyloides stercoralis en las heces de la paciente. Aunque existen evidencias de casos fatales de pacientes con strongiloidiasis asociada al uso prolongado de esteroides en la literatura internacional, hay escasez de esos reportes en Cuba. Adicionalmente, es probable que el diagnóstico y el tratamiento oportunos, hayan contribuido a evitar complicaciones fatales en esta paciente(AU)

The infection caused by Strongyloides stercoralis may remain asymptomatic or with slight symptoms in humans for decades. However, immunocompromised patients, particulary those receiving long-term steroid therapy, may face hyperinfection resulting in high mortality rates. The objective was to present the first report in Cuba about a patient with chronic strongyloidiasis associated to use of oral steroids. Here is a 63 years-old asthmatic woman, who showed chronic strongyloidiasis symptoms and hyperinfection risk due to the long-term use of oral steroids. The symptoms and physical examination were described as well as various diagnostic tests. Predisposing factors for the onset and development of the disease were discussed. Laboratory diagnosis confirmed the presence of Strongyloides stercoralis rabditoid larvae in the patient's feces. Although there has been evidence of fatal cases with chronic strongyloidiasis associated with long-term use of steroids in the international literature, such reports are rare in Cuba. Additionally, it is likely that timely diagnosis and treatment have contributed to avoid fatal complications in this patient(AU)
Responsable: CU1.1 - Biblioteca Médica Nacional


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Machado, Eleuza Rodrigues
Id: biblio-938375
Author: Machado, Eleuza Rodrigues.
Title: Pesquisa de Strongyloides Stercoralis em crianças usuarias de creches municipais em Uberlandia, Minas Gerais.
Source: Uberlândia; s.n; 1996. 101 p. ilus.
Language: pt.
Thesis: Submitted to Universidade Federal de Uberlândia. Centro de Ciências Biomédicas presented for the degree Mestre.
Responsable: BR1719.1 - Biblioteca do CPqRR
BR1719.1; 616.99, M149p, 1996. 013931


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Id: biblio-937875
Author: Costa, Fernanda Silva da.
Title: Evolução do Strongyloides venezuelensis em camundongos nascidos de mães infectadas com S. venezuelensis ou Schistosoma mansoni.
Source: Belo Horizonte; s.n; 2009. 158 p. ilus.
Language: pt.
Thesis: Submitted to Centro de Pesquisa René Rachou presented for the degree Mestre.
Responsable: BR1719.1 - Biblioteca do CPqRR
BR1719.1; 616.936, C837e, 2009. 014243 e 014244


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Id: biblio-885012
Author: Brandão, Eduardo; Lorena, Virginia Maria Barros de; Fernandes, Amanda Regueira; Romero, Sebastián; Araújo, Paulo Sérgio Ramos de; Bottasso, Oscar; Rocha, Abraham.
Title: Impacto da infecção por HTLV-1 nas manifestações clínicas e no tratamento de pacientes com estrongiloidíase / Impact of HTLV-1 infection on clinical presentations and treatment of strongyloidiasis patients
Source: Rev. Soc. Bras. Clín. Méd;16(1):70-73, 20180000.
Language: pt.
Abstract: A estrongiloidíase é uma enfermidade que acomete cerca de 100 milhões de pessoas em todo mundo. Essa parasitose apresenta alta prevalência e tem maior gravidade clínica entre indivíduos imunossuprimidos, principalmente aqueles portadores do vírus linfotrópico de células T humana tipo 1 (HTLV). Este fato torna a coinfecção por esse vírus em pacientes parasitados por Strongyloides stercoralis um grave problema de saúde pública. O presente estudo teve por objetivo revisar os estudos sobre coinfecção por HTLV/S. stercoralis. Foi realizada busca eletrônica completa de dados disponíveis sobre a coinfecção entre o vírus e S. stercoralis. As publicações foram capturadas a partir das bases de dados PubMed e SciELO, sendo utilizados os seguintes descritores "vírus linfotrópico de células T humanas tipo 1", "HTLV-1", "S. stercoralis" e "estrongiloidiase". A infecção por HTLV em pacientes parasitados representa fator de risco para o desenvolvimento de estrongiloidíase grave e, nesses indivíduos, o tratamento recomendado deve ser realizado e monitorado para garantir o sucesso terapêutico.(AU)

Strongyloidiasis is a disease that affects approximately 100 million people worldwide. This parasitosis is highly prevalent and more clinically severe among immunosuppressed individuals, particularly those with Human T-lymphotropic virus 1 (HTLV-1). This fact makes the co-infection with this virus in patients parasitized by Strongyloides stercoralis a serious public health problem. The present study aimed at reviewing the studies of co-infection with HTLV/S. stercoralis. A complete electronic search for available data about the co-infection of the virusand S. stercoralis was performed. The publications were obtained from the databases PubMed and SciELO, with the following descriptors being used: "Human T-lymphotropic Virus type 1, "HTLV-1", S. stercoralis, and "strongyloidiasis". The infection with HTLV in infected patients is a risk factor for the development of severe strongyloidiasis, and for these individuals the recommended treatment should be performed and monitored to ensure therapeutic success.(AU)
Responsable: BR1610.9 - Regional São Paulo


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Id: lil-788741
Author: Hassan, Imman Fuad Khattab; Farias, Bruna Brandão de; Jannke, Heitor Alberto; Kopereck, Vagner Vencato; Silva, José Francisco Pereira da; Real, Gustavo Gonzales.
Title: Duodenal strongyloidiasis and hyperinfection syndrome: case report and literature review
Source: Clin. biomed. res;36(1):50-53, 2016. ilus.
Language: en.
Abstract: Strongyloides stercoralis is an intestinal nematode that commonly causes chronic or asymptomatic infection, but in some situations, especially in immunosuppressed patients, infection by this parasite can manifest with extreme severity and high mortality. Hyperinfection syndrome and disseminated strongyloidiasis are two serious, life-threatening presentations associated with immunosuppression. This paper aims to report a case of duodenal strongyloidiasis that was associated with malabsorption syndrome and evolved to hyperinfection.
Responsable: BR18.1 - Biblioteca FAMED/HCPA


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Id: lil-788617
Author: Alvarez-Falconí, Pedro P; Moncada-Vilela, Zandra; Montero-Navarrete, Sibyl; Hernandez-García, Jackelyn A.
Title: Reporte de un caso de estrongiloidiasis con coinfección por HTLV-1 y onicomicosis / Report of a case of strongyloidiasis with a coinfection by HTLV-1 and onychomycosis
Source: Rev. gastroenterol. Perú;33(4):348-351, oct.-dic. 2013.
Language: es.
Abstract: La infección por el virus linfotrópico humano de células T tipo 1 (HTLV-1) (HTLV-I), presenta una distribución mundial, estimándose que está propagándose hacia áreas no endémicas para convertirse en un problema de salud pública. La coinfección del HTLV-1 con Strongyloides stercoralis y manifestaciones digestivas no es infrecuente, pero sí lo es la asociación simultánea con otros agentes patógenos ocasionando infecciones bacterianas y onicomicosis múltiple. Presentamos un paciente de 34 años con tales coinfecciones, pero además con compromiso vascular periférico. Se discuten aspectos de la patogenia del HTLV-1, la coinfección con el nemátodo y con los agentes patógenos simultáneos señalados, sugiriendo solicitar la prueba para HTLV-1 en tales casos...

The infection caused by the human T-cell lymphotropic virus type 1 (HTLV-1) (HTLV-I) has a worldwide distribution. This condition has a worldwide distribution and now it is spreading towards non-endemic areas and it is becoming a public health problem. It is not unusual to see patients with HTLV-1 coinfected with Strongyloides stercoralis and presenting with digestive manifestations, but it is less frequent to find the additional occurrence of other pathogens leading to bacterial infections and multiple onychomycosis. We present the case of a 34-year old man with all those coinfections with peripheral vascular involvement. Some aspects of HTLV-1 pathogenesis are discussed, emphasizing the presence of this virus and the other associated pathogens, and we suggest that tests for determining the presence of HTLV-1 infection may be requested in such cases...
Responsable: PE1.1 - Oficina Universitária de Biblioteca



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