Database : LILACS
Search on : D02.241.223.100.050.500.650 [DeCS Category]
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Id: lil-346053
Author: Bardini, Simone; Alano, Aletéia S; Limberger, Renata; Xavier, Ana Lúcia; Steffen, Vera M.
Title: Doseamento de ácido hipúrico na urina de sapateiros de Porto Alegre e da grande Porto Alegre / Hipuric acid dosing in the urine of the shoemaker from Porto Alegre and the neighborhood
Source: Rev. bras. anal. clin;34(3):143-144, 2002.
Language: pt.
Abstract: Este trabalho tem como objetivo fazer um estudo de toxicologia ocupacional, verificando se os sapateiros que ficam expostos ao tolueno (que é o solvente da cola) têm o ácido hipúrico (que é um metabólito do tolueno) aumentado. Para isto, foi realizado monitoramento biológico fazendo-se doseamento do ácido hipúrico, por cromatografia gasosa, na urina e foi aplicado um questionário para obter-se informaçöes relevantes para o trabalho. Este estudo foi realizado com sapateiros de Porto Alegre e da grande Porto Alegre. Analisando os resultados obtidos concluímos que os níveis de ácido hipúrico ficaram dentro dos valores de IBMP (índice biológico máximo permitido)
Responsable: BR408.1 - Biblioteca da Faculdade de Medicina - BFM


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SciELO Brazil full text
Siqueira, Maria Elisa P. B
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Id: lil-326387
Author: Siqueira, Maria Elisa P. B; Paiva, Maria José N.
Title: Hippuric acid in urine: reference values
Source: Rev. saúde pública = J. public health;36(6):723-727, dez. 2002. tab, graf.
Language: en.
Conference: Present in: Congresso Brasileiro de Toxicologia, 9, Guarujá, 1999.
Abstract: OBJECTIVE: To establish reference values for hippuric acid (HA) excreted in the urine, and to evaluate the impact of age, gender, alcohol, and tobacco, on these levels in a population nonexposed to toluene. METHODS: Reference values for hippuric acid in urine were determined in 115 toluene nonexposed healthy volunteers, from Alfenas city, Southeastern Brazil. A questionnaire was applied to each volunteer and data on occupational and personal habits were collected. Biochemical and hematological analyses were used to confirm the volunteers' good health condition. Reference values were expressed in g HA/g urine creatinine, as mean Ý standard deviation (x Ý SD), median, 95 percent confidence interval (95 percentCI), 95th percentile, and upper reference value (URV, mean +2 SD). RESULTS: Reference values of hippuric acid in urine were: mean Ý standard deviation =0.18Ý0.10; median =0.15; 95 percent confidence interval =0.16Ý0.20; 95th percentile = 0.36 and upper reference value (URV, mean +2 SD) =0.38. Statistically significant differences in urinary HA (Wilcoxon - Mann/Whitney, p<0.05) were observed for different genders and age groups. Alcohol ingestion and smoking habit did not significantly affect the results. CONCLUSIONS: The reference values of hippuric acid in urine can be used in biomonitoring programs of workers occupationally exposed to toluene, especially in the southern region of the state of Minas Gerais. Age and gender may affect the HA reference values
Responsable: BR67.1 - CIR - Biblioteca - Centro de Informação e Referência



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