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Id: biblio-1040128
Autor: Ergul-Erkec, Ozlem.
Título: Relationships between the 2D: 4D digit ratio, waist circumference, hand preferences, weight, height, waist-to-height ratio and BMI in a Turkish population / Relaciones entre el promedio de dígitos 2D: 4D, circunferencia de cintura, preferencias de mano, peso, altura, relación de cintura a altura e IMC en una población de turquía
Fonte: Int. j. morphol;37(4):1299-1304, Dec. 2019. tab.
Idioma: en.
Resumo: The 2D:4D is thought as a biomarker for prenatal androgen exposure. Some studies have reported a significant difference between the sexes. Earlier studies reported variations in different ethnic and geographic groups. 2D:4D is related to several medical conditions including cardiovascular diseases (CVD) and metabolic syndrome (MetS). The present study investigated the relationships between hand preference, ratio of the index finger (2nd digit: 2D) and ring finger (4th digit: 4D) lengths (2D:4D), height, waist-to-height ratio (WHtR), waist circumference (WC) and weight, body mass index (BMI) in a Turkish population. The study comprised 118 healthy subjects (68 males and 50 females). 2D and 4D finger lengths and some anthropometric traits (height, weight, WC) were measured. The BMI and WHtR were calculated. Hand preference was determined by using a questionnaire (Edinburgh handedness inventory). Geschwind scores were calculated to evaluate the degree of hand preference. The mean age was 26.74 (female 27.86, male 25.89). The right hand 2D:4D was found significantly lower in males (0.9797) than in females (0.9922) (p< 0.001), but the left hand 2D:4D was insignificant. Significant correlations (negative) were observed between the 2D:4D (both left and right) and WHtR; the 2D:4D ratio (both left and right) and WC in males. However, in females, these correlations were insignificant. The R2D:4D was sexually dimorphic in a Turkish population. There were significant differences between strong right (SR) and weak left (WL) in terms of the R2D:4D. However only 5 subject's hand preference was found WL. Therefore, further studies are needed to determine the relationships between hand preference and R2D:4D in Turkish population. Further studies are needed to determine whether a larger sample population alters these possible associations between the ratio of 2D:4D and other investigated traits in a Turkish population.

El 2D:4D está pensado como un biomarcador para la exposición prenatal de andrógenos. Algunos estudios han reportado una diferencia significativa entre sexos. Estudios anteriores informaron variaciones en diferentes grupos étnicos y geográficos. 2D:4D está relacionado con varias afecciones médicas que incluyen enfermedades cardiovasculares (ECV) y síndrome metabólico (MetS). El presente estudio investigó las relaciones entre la preferencia de la mano, la proporción del dedo índice (2º dígito: 2D) y el dedo anular (4º dígito: 4D), longitudes (2D:4D), altura, relación cintura-altura (WHtR), circunferencia de cintura y peso (WC), e índice de masa corporal (IMC), en una población de Turquía. El estudio incluyó 118 sujetos sanos (68 hombres y 50 mujeres). Se midieron longitudes de dedos 2D y 4D y algunos rasgos antropométricos (altura, peso, WC). Se calcularon el IMC y el WHtR. La preferencia de la mano se determinó mediante el uso de una escala (Edinburgh Handedness Inventory). Las puntuaciones de Geschwind se calcularon para evaluar el grado de preferencia de la mano. La edad media fue de 26,74 años (femenino 27,86; masculino 25,89). La mano derecha 2D: 4D se encontró significativamente más baja en los hombres (0,9797) que en las mujeres (0,9922) (p <0,001), pero la mano izquierda 2D: 4D fue no significante. Se observaron correlaciones significativas (negativas) entre la 2D: 4D (izquierda y derecha) y WHtR y la relación 2D: 4D (izquierda y derecha) y WC en hombres. Sin embargo, en las mujeres, estas correlaciones fueron no significantes. El R2D: 4D fue sexualmente dimorfo en una población de Turquía. Hubo diferencias significativas entre la mano derecha fuerte (SR) y la mano izquierda débil (WL) en términos de R2D: 4D. Sin embargo, sólo se encontraron 5 preferencias de mano en el sujeto con WL. Por lo tanto, se necesitan más estudios para determinar las relaciones entre la preferencia de mano y R2D: 4D en la población de Turquía. Se necesitan más estudios para determinar si una muestra mayor altera estas posibles asociaciones entre la proporción de 2D: 4D y otros rasgos investigados en una población de Turquía.
Descritores: Antropometria/métodos
Dedos/anatomia & histologia
Lateralidade Funcional
-Turquia
Estatura
Peso Corporal
Índice de Massa Corporal
Circunferência da Cintura
Limites: Seres Humanos
Masculino
Feminino
Adolescente
Adulto
Meia-Idade
Adulto Jovem
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-838061
Autor: Paiva, Elaine Crystine Vieira de; Bezerra, Natália Tomaz; Valença Júnior, José Telmo; Sousa, Antônio Renê Diógenes de.
Título: Inflammatory mixo-hyaline tumor of distal extremities - a rare sarcoma simulating benign diseases
Fonte: An. bras. dermatol;92(2):292-294, Mar.-Apr. 2017. graf.
Idioma: en.
Descritores: Sarcoma/patologia
Neoplasias Cutâneas/patologia
Doenças da Unha/patologia
-Pele/patologia
Biópsia
Imuno-Histoquímica
Doenças Raras
Dedos/patologia
Hialina
Limites: Seres Humanos
Feminino
Meia-Idade
Tipo de Publ: Relatos de Casos
Carta
Responsável: BR1.1 - BIREME


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Id: biblio-887194
Autor: Souza, Bruno de Castro e; Ribeiro, Caroline Paias; Swiczar, Bethânia Cabral Cavalli; Pires, Mário Cezar.
Título: Diphenciprone as a therapeutic alternative to exuberant periungual warts
Fonte: An. bras. dermatol;93(2):305-307, Mar.-Apr. 2018. graf.
Idioma: en.
Descritores: Verrugas/tratamento farmacológico
Ciclopropanos/uso terapêutico
Fatores Imunológicos/uso terapêutico
Doenças da Unha/tratamento farmacológico
-Resultado do Tratamento
Dedos/patologia
Dedos/virologia
Doenças da Unha/virologia
Limites: Seres Humanos
Feminino
Adolescente
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


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Id: biblio-1011107
Autor: İslamoğlu, Zeynep Gizem Kaya.
Título: Second-to-fourth digit ratio and seborrheic dermatitis in males: a cross-sectional study*
Fonte: An. bras. dermatol;94(3):327-330, May-June 2019. tab.
Idioma: en.
Resumo: Abstract: Background: Seborrheic dermatitis is a common disease characterized by the erythematous plaques with oily-yellow desquamation. Increased sebaceous gland activity by androgenic hormones has played a role in the etiology of the disease. The second-to-fourth digit (2D:4D) ratio is thought to be a marker of prenatal androgen exposure. Objectives: To investigate the association between 2D:4D ratios and seborrheic dermatitis in a male population. Methods: Healthy male controls and patients with seborrheic dermatitis were included in this study. One hundred seborrheic dermatitis patients and 120 healthy controls, aged 17-59, were enrolled. A digital Vernier caliper was used to measure the finger lengths. Seborrheic dermatitis severity was assessed using the Seborrheic Dermatitis Area and Severity Index (SDASI). Results: The 2D:4D ratios of the patients (x = 0.977) were significantly lower than those of the controls (x = 1.050) for right hands (t = 6.948; p = 0.000; > 0.05). No similar relationship was found between the 2D:4D ratio for left hands (t = 0.901; p = 0.368; > 0.05). Seborrheic dermatitis severity was negatively correlated with 2D:4D ratios of right hands (r = -0.391; p = 0.000-0.05). Study limitations: One of the main limitations of this study was the small sample, which got a head of us from acquiring certain findings about the 2D:4D ratio and seborrheic dermatitis. The other limitation is that the patient selection did not reflect the general population, as a single clinic was studied. Conclusion: To the authors' knowledge, this is the first study examining the relationship between 2D:4D ratios and seborrheic dermatitis. The result of this study may indicate a line of investigation and can support the theory of prenatal androgen exposure.
Descritores: Dermatite Seborreica/diagnóstico
Dedos/anatomia & histologia
-Tamanho do Órgão
Efeitos Tardios da Exposição Pré-Natal
Índice de Gravidade de Doença
Gravidez
Biomarcadores
Estudos de Casos e Controles
Antropometria
Mãos/anatomia & histologia
Androgênios/metabolismo
Limites: Seres Humanos
Masculino
Feminino
Adolescente
Adulto
Meia-Idade
Adulto Jovem
Responsável: BR1.1 - BIREME


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Id: lil-706981
Autor: Franco, Joanna Pimenta de Araujo; Barbosa, Caroline Cruz; Fonseca, Bárbara Ferreira Saraiva da; Lima, Ricardo Barbosa; D'Acri, Antônio Macedo; Martins, Carlos José.
Título: Case for diagnosis
Fonte: An. bras. dermatol;89(2):357-358, Mar-Apr/2014. graf.
Idioma: en.
Resumo: Dermatofibrosarcoma protuberans is a fibrohistiocytic tumor of intermediate malignancy with aggressive localized growth, high recurrence rate, but low metastatic potential. It appears as a hardened plaque, with slow growth, upon which the development of nodules occurs. It predominates in the trunk and is unusual in acral locations. Histopathology reveals spindle cells with storiform pattern and cartwheel-like or whirlwind-like aspect. Immunohistochemistry shows positivity for CD34. The treatment is surgical. We report a case of long evolution, with an unusual location, that relapsed after surgery, to emphasize the importance of early diagnosis and proper treatment, avoiding aggressive resections with increased morbidity.
Descritores: Neoplasias Cutâneas/patologia
Dermatofibrossarcoma/patologia
-Neoplasias Cutâneas/cirurgia
Biópsia
Imuno-Histoquímica
Resultado do Tratamento
Dermatofibrossarcoma/cirurgia
Dedos/patologia
Limites: Seres Humanos
Feminino
Meia-Idade
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


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Id: lil-749667
Autor: Chiacchio, Nilton Di; Jasso-Olivares, Julio Cesar; Chiacchio, Nilton Gioia Di; Jacinto, José Antonio; Restrepo, Maria Victoria Suárez.
Título: Syndrome in question
Fonte: An. bras. dermatol;90(3):423-425, May-Jun/2015. graf.
Idioma: en.
Resumo: Abstract The Iso-Kikuchi Syndrome is a rare condition characterized by nail dysplasia involving the index fingers, including micronychia, polyonychia, anonychia, irregular lunula, malalignment and hemionychogryphosis. On the antero-posterior image, radiologic examination reveals a narrowing of the distal phalanx. The lateral image shows a Y-shaped bifurcation of the distal phalanx. We report a case of a patient with typical clinical and radiologic signs of Iso-Kikuchi Syndrome.
Descritores: Falanges dos Dedos da Mão
Unhas Malformadas
-Síndrome
Radiografia
Doenças Raras/congênito
Doenças Raras/diagnóstico por imagem
Falanges dos Dedos da Mão/anormalidades
Falanges dos Dedos da Mão/diagnóstico por imagem
Dedos/anormalidades
Dedos/diagnóstico por imagem
Unhas Malformadas/congênito
Unhas Malformadas/diagnóstico por imagem
Limites: Seres Humanos
Masculino
Adolescente
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


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Id: biblio-837976
Autor: Çerman, Asli Aksu; Altunay, Ilknur Kivanç; Salman, Kübra Esen; Tunçel, Deniz.
Título: Finger pad tophi in gout: a rare presentation
Fonte: An. bras. dermatol;91(6):855-856, Nov.-Dec. 2016. graf.
Idioma: en.
Descritores: Dedos/patologia
Gota/patologia
Dermatoses da Mão/patologia
-Biópsia
Derme/patologia
Limites: Seres Humanos
Masculino
Idoso
Tipo de Publ: Relatos de Casos
Carta
Responsável: BR1.1 - BIREME


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Id: lil-781366
Autor: Bilgic, Özlem; Altınyazar, Hilmi Cevdet; Eryılmaz, Dilek; Tuğrul, Zehra Ayça.
Título: Are 2D: 4D finger-length ratios an indicator of androgenetic alopecia in males?
Fonte: An. bras. dermatol;91(2):156-159, Mar.-Apr. 2016. tab.
Idioma: en.
Resumo: Abstract BACKGROUND: Although the pathogenesis of androgenetic alopecia is not completely understood, the roles of genetic susceptibility and androgens are well-known. A lower ratio of the second digit (index finger = 2D) to the fourth digit (ring finger = 4D) length has been hypothesized to reflect prenatal androgen exposure and/or higher sensitivity to androgens. OBJECTIVES: To determine the relationship between the second to fourth digit length ratio and androgenetic alopecia. METHODS: Finger length measurements were made by a digital vernier calliper. Androgenetic alopecia severity was assessed using the Hamilton-Norwood scale. Subjects with an androgenetic alopecia score of grade III or more were included in the study. RESULTS: A total of 189 males with androgenetic alopecia and 171 healthy controls were enrolled in the study. The age range of participants was 19-65 years. The 2D:4D ratios in patients with androgenetic alopecia were significantly lower than those of healthy controls for the right hand; however, no significant difference was found for the left hand. Average 2D:4D ratios in androgenetic alopecia patients were also lower than in controls. No significant relationship was observed between androgenetic alopecia severity and 2D:4D ratios. CONCLUSION: Our data support the anatomical evidence of in utero androgen exposure and/or an individual’s sensitivity to androgens in patients with androgenetic alopecia. Furthermore, the right hand 2D:4D ratio might be an indicator of androgenetic alopecia development.
Descritores: Efeitos Tardios da Exposição Pré-Natal/diagnóstico
Alopecia/diagnóstico
Dedos/anatomia & histologia
-Tamanho do Órgão
Padrões de Referência
Valores de Referência
Índice de Gravidade de Doença
Gravidez
Marcadores Genéticos
Estudos de Casos e Controles
Antropometria/métodos
Valor Preditivo dos Testes
Reprodutibilidade dos Testes
Predisposição Genética para Doença
Alopecia/etiologia
Androgênios/análise
Androgênios/fisiologia
Limites: Seres Humanos
Masculino
Feminino
Adulto
Idoso
Adulto Jovem
Responsável: BR1.1 - BIREME


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Id: biblio-838219
Autor: D'Amato Gutiérrez, Mónica; Palacio Díaz, Felipe A.
Título: Reporte de caso de síndrome FATCO: aplasia fibular, campomelia de tibia y oligosindactilia / A case report of a patient with FATCO syndrome: fibular aplasia, tibial campomelia and oligosyndactyly
Fonte: Arch. argent. pediatr;114(3):e167-e170, jun. 2016. ilus.
Idioma: es.
Resumo: El síndrome FATCO, por las siglas en inglés de aplasia fibular (Fibular Aplasia), campomelia de tibia (Tibial Campomelia) y oligosindactilia (Oligosyndactyly), es un conjunto de malformaciones óseas, en las que la alteración se centra en los huesos de la pierna. Es una entidad rara y hay pocos casos descritos en la Literatura internacional, y, hasta ahora, no se ha descrito ningún caso en Colombia. Presentamos aquí el caso de un recién nacido de sexo masculino con signos clínicos de manera prenatal y posnatal consistentes con síndrome FATCO sin otras malformaciones asociadas. Exponemos también una breve discusión sobre las diferentes malformaciones óseas y otros casos de FATCO en el mundo.

The FATCO syndrome, (Fibular Aplasia, Tibial Campomelia and Oligosyndactyly) are bone malformations with main alteration in lower limbs. It is a rare entity and there are few cases reported in international literature, and so far there are not published cases in Colombia. Here we present a case of a male newborn with prenatal and postnatal signs consistent with FATCO syndrome without other organs malformations, and there is a brief discussion about this syndrome and other different malformations associated with it.
Descritores: Deformidades Congênitas do Pé/diagnóstico
Deformidades Congênitas da Mão/diagnóstico
Sindactilia/diagnóstico
Displasia Campomélica/diagnóstico
-Tíbia/anormalidades
Dedos do Pé/anormalidades
Fíbula/anormalidades
Dedos/anormalidades
Limites: Seres Humanos
Masculino
Recém-Nascido
Tipo de Publ: Relatos de Casos
Responsável: AR94.1 - Centro de Información Pediatrica


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Id: lil-781427
Autor: Yang, Yi; Zou, Xue-jun; Fu, Guo; Qin, Ben-Gang; Yang, Jian-Tao; Li, Xiang-Ming; Hou, Yi; Qi, Jian; Li, Ping; Liu, Xiao-Lin; Gu, Li-Qiang.
Título: Neurotization of free gracilis transfer with the brachialis branch of the musculocutaneous nerve to restore finger and thumb flexion in lower trunk brachial plexus injury: an anatomical study and case report
Fonte: Clinics;71(4):193-198, Apr. 2016. tab, graf.
Idioma: en.
Projeto: National Natural Science Foundation; . National Key Clinical Specialist Construction Programs of China.
Resumo: OBJECTIVE: To investigate the feasibility of using free gracilis muscle transfer along with the brachialis muscle branch of the musculocutaneous nerve to restore finger and thumb flexion in lower trunk brachial plexus injury according to an anatomical study and a case report. METHODS: Thirty formalin-fixed upper extremities from 15 adult cadavers were used in this study. The distance from the point at which the brachialis muscle branch of the musculocutaneous nerve originates to the midpoint of the humeral condylar was measured, as well as the length, diameter, course and branch type of the brachialis muscle branch of the musculocutaneous nerve. An 18-year-old male who sustained an injury to the left brachial plexus underwent free gracilis transfer using the brachialis muscle branch of the musculocutaneous nerve as the donor nerve to restore finger and thumb flexion. Elbow flexion power and hand grip strength were recorded according to British Medical Research Council standards. Postoperative measures of the total active motion of the fingers were obtained monthly. RESULTS: The mean length and diameter of the brachialis muscle branch of the musculocutaneous nerve were 52.66±6.45 and 1.39±0.09 mm, respectively, and three branching types were observed. For the patient, the first gracilis contraction occurred during the 4th month. A noticeable improvement was observed in digit flexion one year later; the muscle power was M4, and the total active motion of the fingers was 209°. CONCLUSIONS: Repairing injury to the lower trunk of the brachial plexus by transferring the brachialis muscle branch of the musculocutaneous nerve to the anterior branch of the obturator nerve using a tension-free direct suture is technically feasible, and the clinical outcome was satisfactory in a single surgical patient.
Descritores: Transferência Tendinosa/métodos
Plexo Braquial/lesões
Neuropatias do Plexo Braquial/cirurgia
Dedos/fisiologia
Músculo Grácil/cirurgia
Músculo Grácil/inervação
Nervo Musculocutâneo/transplante
-Polegar/fisiologia
Cadáver
Estudos de Viabilidade
Transferência de Nervo/métodos
Amplitude de Movimento Articular/fisiologia
Força da Mão/fisiologia
Neuropatias do Plexo Braquial/fisiopatologia
Limites: Seres Humanos
Masculino
Adolescente
Responsável: BR1.1 - BIREME



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