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Id: biblio-1146468
Autor: Delgado G, José F; Pérez E, Javiera; Delgado B, Dasha; Valenzuela P, Felipe; Martínez G, Alejandra; Arteaga U, Eugenio.
Título: Síndrome de insensibilidad a andrógenos: revisión bibliográfica a propósito de 5 casos / Androgen insensitivity syndrome: literature review about 5 cases
Fonte: Rev. chil. endocrinol. diabetes;14(1):21-28, 2021. ilus, tab.
Idioma: es.
Resumo: El síndrome de insensibilidad a andrógenos (AIS en la sigla inglesa) es una entidad muy poco frecuente en endocrinología. Se caracteriza por la mutación del receptor de andrógenos de magnitud variable, por medio del cual individuos 46,XY no se virilizan normalmente, a pesar de conservar sus testículos y tener concentraciones de testosterona en rango masculino. El cuadro clínico es variable y depende la profundidad de la alteración del receptor. En un extremo, hay casos de insensibilidad androgénica completa (CAIS) con fenotipo femenino. En el otro extremo hay insensibilidad parcial (PAIS) que se extiende desde el fenotipo femenino, con o sin ambigüedad genital, hasta los casos de hombres infértiles o con subvirilización, que presentan insensibilidad androgénica más leve. En los fenotipos femeninos, los testículos suelen estar en posición ectópica y aquellos ubicados dentro del abdomen tienen riesgo de malignizarse, por lo que suelen extirparse. Estos son los casos de más difícil manejo, pues aparte de la necesidad de gonadectomía seguida de terapia hormonal femenina, existe una vagina estrecha y en fondo de saco ciego y que suele requerir corrección quirúrgica para permitir la actividad sexual. En este trabajo presentamos 5 casos de AIS vistos recientemente en 2 centros clínicos de Santiago y que ilustran la heterogeneidad de presentación. Además, hacemos una revisión actualizada de los criterios diagnósticos, los tratamientos más adecuados y el manejo global de esta condición.

The Androgen insensitivity syndrome (AIS, in its English acronym) is a very rare entity in endocrinology. It is characterized by a variable magnitude androgen receptor mutation, whereby 46, XY individuals are not normally virilized, despite retaining their testicles and having testosterone concentrations in the male range. The clinical picture is variable and depends on the depth of the receptor alteration. At one extreme, there are cases of complete androgenic insensitivity (CAIS) with a female phenotype. At the other extreme, there is partial insensitivity (PAIS) that extends from the female phenotype, with or without genital ambiguity, to cases of infertile or undervirilized men, who have milder androgenic insensitivity. In female phenotypes, the testes are usually in an ectopic position and those located within the abdomen are at risk of malignancy, and therefore are usually removed. These are the most difficult cases to manage because apart from the need for gonadectomy followed by female hormonal therapy, there is a narrow vagina and a deep blind pouch that usually requires surgical correction to allow sexual activity. In this work, we present 5 cases of AIS recently seen in 2 clinical centers in Santiago and that illustrate the heterogeneity of presentation. In addition, we make an updated review of the diagnostic criteria, the most appropriate treatments, and the overall management of this condition.
Descritores: Síndrome de Resistência a Andrógenos/diagnóstico
-Fenótipo
Transtornos do Desenvolvimento Sexual
Síndrome de Resistência a Andrógenos/genética
Síndrome de Resistência a Andrógenos/terapia
Testículo
Imagem por Ressonância Magnética
Receptores Androgênicos
Tomografia Computadorizada por Raios X
Diagnóstico Diferencial
Limites: Humanos
Feminino
Adolescente
Adulto
Pessoa de Meia-Idade
Adulto Jovem
Tipo de Publ: Relatos de Casos
Revisão
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-950898
Autor: Diao, Ruiying; Cai, Xueyong; Liu, Lu; Yang, Lihua; Duan, YongGang; Cai, Zhiming; Gui, Yaoting; Mou, Lisha.
Título: In vitro chemokine (C-C motif) receptor 6-dependent non-inflammatory chemotaxis during spermatogenesis
Fonte: Biol. Res;51:12, 2018. graf.
Idioma: en.
Projeto: National Natural Science Foundation of China; . Guangdong Natural Science Foundation; . Shenzhen Foundation of Science and Technology; . Medical Scientific Research Foundation of Guangdong.
Resumo: BACKGROUND: Chemokine (C-C motif) receptor 6 (CCR6) is present in sperm and plays a significant role in sperm motility and chemotaxis acting in the reproductive tracts. However, the expression and functional significance of CCR6 in testis are still poorly understood, especially in the process of spermatogenesis. METHODS AND RESULTS: CCR6 was expressed in spermatogenic cell lines and its expression was shown in an age-dependent upregulation manner from puberty to adulthood in mouse testis. Immunostaining results confirmed the localization of CCR 6 in testis. Further chemotaxis assays demonstrated that spermatogenic cells GC-1 and -2 exhibited a directional movement toward CCR6-specific ligand such as CCL20 or Sertoli cells in vitro. CONCLUSIONS: The present findings indicate that CCR6 is involved in the chemotaxis of spermatogenic cells in vitro and promotes chemotaxis under non-inflammatory conditions during normal spermatogenesis.
Descritores: Espermatogênese/fisiologia
Quimiotaxia/fisiologia
Criptorquidismo/metabolismo
Quimiocina CCL20/metabolismo
Receptores CCR6/metabolismo
-Células de Sertoli
Motilidade Espermática/fisiologia
Testículo/fisiologia
Imuno-Histoquímica
Western Blotting
Imunofluorescência
Camundongos Endogâmicos C57BL
Limites: Humanos
Animais
Masculino
Camundongos
Coelhos
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-1011418
Autor: Mohaqiq, Mahdi; Movahedin, Mansoureh; Mazaheri, Zohreh; Amirjannati, Naser.
Título: In vitro transplantation of spermatogonial stem cells isolated from human frozen-thawed testis tissue can induce spermatogenesis under 3-dimensional tissue culture conditions
Fonte: Biol. Res;52:16, 2019. tab, graf.
Idioma: en.
Resumo: BACKGROUND: Sperm production is one of the most complex biological processes in the body. In vitro production of sperm is one of the most important goals of researches in the field of male infertility treatment, which is very important in male cancer patients treated with gonadotoxic methods and drugs. In this study, we examine the progression of spermatogenesis after transplantation of spermatogonial stem cells under conditions of testicular tissue culture. RESULTS: Testicular tissue samples from azoospermic patients were obtained and then these were freeze-thawed. Spermatogonial stem cells were isolated by two enzymatic digestion steps and the identification of these cells was confirmed by detecting the PLZF protein. These cells, after being labeled with DiI, were transplanted in azoospermia adult mice model. The host testes were placed on agarose gel as tissue culture system. After 8 weeks, histomorphometric, immunohistochemical and molecular studies were performed. The results of histomorphometric studies showed that the mean number of spermatogonial cells, spermatocytes and spermatids in the experimental group was significantly more than the control group (without transplantation) (P < 0.05) and most of the cells responded positively to the detection of DiI. Immunohistochemical studies in host testes fragments in the experimental group express the PLZF, SCP3 and ACRBP proteins in spermatogonial cells, spermatocyte and spermatozoa, respectively, which confirmed the human nature of these cells. Also, in molecular studies of PLZF, Tekt1 and TP1, the results indicated that the genes were positive in the test group, while not in the control group. CONCLUSION: These results suggest that the slow freezing of SSCs can support the induction of spermatogenesis to produce haploid cells under the 3-dimensional testicular tissue culture.
Descritores: Espermatogênese/fisiologia
Espermatogônias/transplante
Testículo/citologia
Criopreservação/métodos
Transplante de Células-Tronco/métodos
Limites: Humanos
Animais
Masculino
Camundongos
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-1144548
Autor: Mantilla Toloza, Sonia Carolina; Martínez Torres, Javier; Carrasco Villamizar, Cesar.
Título: Conocimiento del autoexamen de mama y testículo en estudiantes universitarios / Knowledge of university students on breasts and testicles self-examination
Fonte: Rev. cuba. salud pública;46(3):e1571, jul.-set. 2020. tab.
Idioma: es.
Resumo: Introducción: El autoexamen de mama y el autoexamen de testículos son métodos de detección temprana sencillos, económicos, seguros, no invasivos, que no requieren ningún instrumento especial para su ejecución y que permiten una mayor conciencia y conocimiento del propio cuerpo. Objetivo: Determinar el conocimiento de la práctica del autoexamen de mama o testículo en un grupo de estudiantes universitarios. Métodos: Estudio descriptivo, transversal. Se aplicó un cuestionario sobre conocimientos de autoexamen de mama o testículo, consumo de tabaco, alcohol y variables sociodemográficas. El análisis de datos incluyó distribución de frecuencias, porcentajes y razones de prevalencia. Resultados: Del total de la muestra, el 43,9 por ciento eran hombres, de ellos el 30,7 por ciento manifestó conocer cómo se debía realizar el autoexamen de testículo. Los masculinos pertenecientes a estratos altos, los que se encontraban cursando tercer año y quienes tenían estudios afines con la facultad de salud mostraron las mayores tasas de conocimiento. De las mujeres, el 73,7 por ciento conocía cómo realizar el autoexamen de mama, demostrando tasas mayores de conocimientos las que cursaban cuarto año, las que pertenecían a estratos altos y las que tenían estudios afines con la facultad de salud. No se encontró asociación estadística con el conocimiento del autoexamen de testículo; mientras que ser mayor de 22 años y pertenecer a estratos altos fueron factores predisponentes para el autoexamen de mama. Conclusiones: Las mujeres tienen mayor percepción de la importancia del autocuidado para su salud, a la vez que manifiestan mayor conocimiento de los procedimientos para realizar el autoexamen. No obstante, existen hombres y mujeres que no saben aún como realizarlo, de ahí la importancia de desarrollar e implementar programas de educación, prevención y promoción del autoexamen en los estudiantes universitarios(AU)

Introduction: Breasts self-examination and testicles self-examination are simple, economic, safe, non-invasive early detection's methods that do not require any special tool for their performance and that foster a higher awareness and knowledge on your own body. Objective: To determine the knowledge of the breast or testicles self-examination practice in a group of university students. Methods: Descriptive, cross-sectional study. It was performed a questionnaire on the knowledge of the breast or testicles self-examination, tobacco and alcohol consumption, and socio-demographic variables. Data analysis included frequencies and percentages distribution, and prevalence ratios. Results: From the total of the sample, 43,9 percent were men, and 30,7 percent of them expressed to have knowledge on how to perform the testicles self-examination. Males corresponding to high strata, the ones that were in third year of the major, and those who had studies related to the Health's Faculty showed higher rates of knowledge. From women, 73,7 percent knew how to perform the breasts self-examination showing higher rates of knowledge the ones that were in the fourth year of the major, the ones that belonged to higher strata and the ones that had studies related with the Health's Faculty. There was not found statistic association with the knowledge on testicles self-examination; while being older than 22 years old and belonging to high strata were predisposing factors for breasts self-examination. Conclusions: Women have higher perception of the importance for health of self-care, while they show more knowledge on the procedures to perform self-examination. Nevertheless, there are men and women that do not know yet how to perform it, that is why it is important to develop and implement programs of education, prevention and promotion of the self-examination in university students(AU)
Descritores: Prevenção Primária/métodos
Testículo/anormalidades
Autoexame de Mama/métodos
-Estudantes
Epidemiologia Descritiva
Estudos Transversais
Limites: Humanos
Masculino
Feminino
Responsável: CU1.1 - Biblioteca Médica Nacional


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Id: biblio-968970
Autor: Mehanna, Mahmoud; Ferreira, André Luís Souza; Ferreira, Adelina; Paz, Regina Célia Rodrigues da; Morgado, Thaís Oliveira.
Título: Histology of the testis and the epididymal ducts from hoary fox Lycalopex vetulus (Lund, 1842) / Histologia dos testículos e ductos epididimários da raposa-do-campo Lycalopex vetulus (Lund, 1842)
Fonte: Biosci. j. (Online);34(6):1697-1705, nov.-dec. 2018. ilus.
Idioma: en.
Resumo: The hoary fox Lycalopex vetulus (Lund, 1842) is a small canid, endemic to Brazil, belonging to the Canidae family, widely distributed in the country, occurring records in different regions and habitats. The objective of this study is to describe morphologically the testicles and epididymal ducts of hoary fox. The animals, coming from the zoo of Federal University of Mato Grosso, Brazil, had died by natural causes. The male reproductive system was dissected to collect the testicles. The samples were fragmented and histologically examined. Microscopically, the testes were coated by the vaginal and albuginea tunic, formed by modeled dense connective tissue with large amount of collagen fibers. Into the organ, convoluted seminiferous tubules were surrounded by a basement membrane characterized by the presence of myoid and Sertoli cells and germinative epithelium composed by Between the seminiferous tubules, interstitial tissue composed of connective tissue, blood and lymph vessels and Leydig cells in polyhedral shape was present. The epididymal ducts showed pseudostratified columnar epithelium with secretory cells, in which stereocilia located on a basement membrane filled by myoid cells were found. The structures observed by us are very similar to those described for other mammals.(AU)

A raposa-do-campo Lycalopex vetulus (Lund, 1842) é um canídeo de pequeno porte, endêmico do Brasil, pertencente a família Canidae, com ampla distribuição no país, ocorrendo registros em várias regiões e habitats diferentes. Com base nessa informação, o objetivo deste trabalho é caracterizar morfologicamente os testículos e ductos epididimários da raposa-do-campo. O animal, oriundo do zoológico da Universidade Federal de Mato Grosso, Brasil, veio a óbito por causas naturais e o sistema reprodutor masculino foi dissecado para coleta dos testículos. As amostras retiradas foram fragmentadas e histológicamente examinadas. A partir das análises microscópicas dos testículos foram identificados: a túnica vaginal e albugínea, formada por tecido conjuntivo denso modelado, com grande quantidade de fibras colágenas; túbulos seminíferos enovelados e revestidos por epitélio germinativo e células de Sertoli, envolvidos por uma membrana basal com presença de células mioides; tecido intersticial entre os túbulos seminíferos constituído de tecido conjuntivo, vasos sanguíneos e linfáticos, e células de Leydig em formato poliédrico. Os ductos epididimários apresentaram epitélio cilíndrico pseudoestratificado com células secretoras dos quais projetam estereocílios, situados sobre uma membrana basal repleta por células mióides. As estruturas por nós observadas possuem muita semelhança com as demais descrições para mamíferos.(AU)
Descritores: Testículo
Raposas
Genitália Masculina
-Túbulos Seminíferos
Células de Sertoli
Membrana Basal
Tecido Conjuntivo
Canidae
Estereocílios
Células Intersticiais do Testículo
Responsável: BR396.1 - Biblioteca Central


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Id: biblio-1131517
Autor: Morais, R. C. L; Dutra, G. A; Oliveira, J. P; Fonseca, F. C. V. L; Carvalho, C. F. P. M; Jacob, J. C. F.
Título: Ultrassonografia testicular no modo color Doppler∕ espectral e avaliação andrológica de garanhões tratados com gonadotrofina coriônica humana (hCG) em diferentes estações do ano / [Testicular ultrasonography in the doppler / spectral color mode and andrological evaluation of stallions treated with human corionic gonadotrofin (hCG) in different seasons of the year]
Fonte: Arq. bras. med. vet. zootec. (Online);72(4):1137-1144, July-Aug. 2020. tab, ilus.
Idioma: pt.
Resumo: Utilizaram-se quatro garanhões nos meses de janeiro, abril, julho e outubro de 2016, em dois protocolos, em que: GI (n=4; 5mL de solução salina, i.v.) e GII (n=4; 5000UI de hCG, i.v.) e subdividiram-se esses protocolos em ciclos (C1 e C2), seguindo o esquema crossover, sendo: CI=animais 1 (GI) e 2 (GII), avaliados nos dias D1, D3 e D5, e animais 3 (GI) e 4 (GII), em D2, D4 e D6; CII= animais 1 (GII) e 2 (GI), em D1, D3, D5, e animais 3 (GII) e 4 (GI), em D2, D4 e D6. Realizou-se o tratamento em D1 e D2 de cada ciclo e a ultrassonografia testicular no modo color Doppler e Doppler espectral, uma hora antes de cada coleta de sêmen e imediatamente após. Avaliou-se: número de reflexo de Flehmen, de montas sem ereção, início da monta, tempo de reação à ereção e total da monta e análises de qualidade seminal. Estatisticamente foram utilizados os testes de qui-quadrado e ANOVA. Não houve diferenças estatísticas (P>0,05) entre os parâmetros analisados. Concluiu-se que uma única dose de 5000UI de hCG em garanhões não causou alterações significativas nos parâmetros avaliados em diferentes estações do ano.(AU)

Four stallions were used in January, April, July and October 2016 in two protocols: GI (n=4; 5ml saline, iv) and GII (n=4; 5000 hCG, iv), and these protocols were subdivided into cycles (C1 and C2) following the cross over scheme, as follows: CI=animal 1 (GI) and 2 (GII) evaluated on days D1, D3 and D5 and animal 3 (GI) and 4 (GII) at D 2, D 4 and D 6; CII=animal 1 (GII) and 2 (GI) at D1, D3, D5 and animal 3 (GII) and 4 (GI) at D2, D4 and D6. Treatment was performed on D1 and D2 of each cycle and testicular ultrasound in color Doppler and spectral Doppler mode, one hour before each semen collection and immediately after. We evaluated: Flehmen's reflex number, mounts without erection, start of the mount, reaction time to erection and total mount and seminal quality analyzes. Statistically, the Chi-square and ANOVA tests were used. There were no statistical differences (P>0.05) between the analyzed parameters. It was concluded that a single dose of 5000IU hCG in stallions did not cause significant changes in the parameters evaluated in different seasons of the year.(AU)
Descritores: Testículo/diagnóstico por imagem
Gonadotropina Coriônica/administração & dosagem
Cavalos/fisiologia
-Estações do Ano
Ultrassonografia Doppler em Cores/veterinária
Limites: Animais
Masculino
Responsável: BR68.1 - Biblioteca Virginie Buff D'Ápice


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Id: lil-589341
Autor: Hoyos Orrego, Álvaro; Botero González, Paula.
Título: Síndrome de prune belly (ciruela pasa): reporte de un caso / Prune belly syndrome: a case report
Fonte: Med. U.P.B = Med. UPB;29(2):155-161, jul.-dic. 2010.
Idioma: es.
Resumo: El síndrome de prune belly es una rara anomalía congénita. Se trata de una triada compuesta por ausencia, deficiencia o hipoplasia de la musculatura de la pared abdominal, criptorquidia bilateral y malformación del tracto urinario (dilatación). Se presenta el caso de un bebé, de sexo masculino y con diagnóstico imagenológico in utero de megavejiga, valvas uretrales posteriores parciales y dilatación de los uréteres. Luego del nacimiento, las características fenotípicas fueron sugestivas del síndrome de prune belly (ciruela pasa). Los estudios complementarios confirmaron la ausencia de testículos en escroto, reflujo vésico ureteral bilateral y estenosis de la uretra proximal. La uro resonancia magnética con reconstrucción en 3D reportó que ambos riñones presentaban alteración en su morfología con quistes en su interior, hipoplasia renal derecha, uréteres dilatados y tortuosos, vejiga distendida con divertículo del uraco y deficiencia de los músculos rectos abdominales. Como complicaciones se presentaron una infección urinaria febril y una enfermedad renal crónica secundaria. Una vez los eventos infeccioso y obstructivo fueron resueltos la función renal se estabilizó y se procedió a realizar vesicostomía. El paciente fue dado de alta en condición estables, con manejo de la vesicostomía, profilaxis para infección urinaria y seguimiento periódico. La reconstrucción de su tracto urinario se realizará al segundo año de vida y de acuerdo con la evolución de su función renal.

Prune belly syndrome is a rare congenital anomaly. It is a triad consisting of absence, deficiency or hypoplasia of wall abdominal muscles, bilateral cryptorchidy, and urinary tract (dilatation) malformation. As an example, take the case of a male baby with in utero diagnostic of megacystis, partial posterior urethral valves, and dilated ureters. After birth, the phenotypic characteristics were suggestive of prune belly syndrome. Complementary studies confirmed the absence of testes in scrotum, bilateralvesicourereteral reflux and stricture of the proximal urethra. Magnetic resonance with 3D reconstruction reported that both kidneys had alterations in their morphology with interior cysts, right renal hypoplasia, long and tortuous ureters, distendedbladder with diverticulum of urachus and deficiency of abdominal muscles. There were complications like febrile urinary tract infection and secondary chronic kidney disease. Once the infectious and obstructive events were resolved the renal function was stabilized and the surgical approach was vesicostomy. The patient was discharged in stable condition, with vesicostomy management, prophylaxis for urinary tract infection and regular follow. The urinary tract reconstruction will be in the second year of life and according to evolution of his kidney function.
Descritores: Síndrome do Abdome em Ameixa Seca
-Escroto
Anormalidades Congênitas
Testículo
Músculos Abdominais
Limites: Humanos
Recém-Nascido
Lactente
Tipo de Publ: Relatos de Casos
Responsável: CO101.1 - BCdeS - Biblioteca Ciencias de la Salud


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Id: biblio-988006
Autor: Moreillo Vicente, Leticia; Callejas Montoya, Miguel; Carrión López, Pedro; Martínez Ruíz, Jesús.
Título: Traumatismo testicular con barra de hierro / Testicular Trauma with Iron bar
Fonte: Rev. argent. urol. (1990);83(4):153-153, 2018. ilus.
Idioma: es.
Descritores: Escroto/cirurgia
Escroto/lesões
Testículo/cirurgia
Testículo/lesões
Testículo/diagnóstico por imagem
Ferimentos Penetrantes/diagnóstico por imagem
-Escroto/diagnóstico por imagem
Ultrassonografia
Limites: Humanos
Masculino
Adulto
Tipo de Publ: Relatos de Casos
Responsável: AR305.1 - SID - Servicio de Información y Documentación


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Id: biblio-1019505
Autor: Wang, Hongyan; Zhou, Weipeng; Zhang, Jing; Li, Huan.
Título: Role of JNK and ERK1/2 MAPK signaling pathway in testicular injury of rats induced by di-N-butyl-phthalate (DBP)
Fonte: Biol. Res;52:41, 2019. tab, graf.
Idioma: en.
Projeto: Science and Technological Project of Jilin Province; . Development and Reform Commission Project of Jilin Province; . Health Technological Innovation Project of Jilin Province; . Nature and Science Fund from Jilin Province Ministry of Education.
Resumo: BACKGROUND: Di-N-butyl-phthalate (DBP) is an endocrine disrupting substance. We investigated the adverse effect of DBP on testis of male rat and reveal its potential mechanism of MAPK signaling pathway involved this effect in vivo and in vitro. Gonadal hormone, sperm quality, morphological change and the activation status of JNK, ERK1/2 and p38 was determined in vivo. Primary Sertoli cell was established and cultivated with JNK, ERK1/2 inhibitors, then determine the cell viability, apoptosis and the expression of p-JNK, p-ERK1/2. Data in this study were presented as mean ± SD and determined by one-way analysis of variance (ANOVA) followed by Bonferroni's test. Difference was considered statistically significant at P < 0.05. RESULTS: In vivo experiment, DBP impaired the normal structure of testicular tissue, reduced testosterone levels in blood serum, decreased sperm count and increased sperm abnormality, p-ERK1/2 and p-JNK in rat testicular tissue increased in a dose-dependent manner. In vitro studies, DBP could decrease the viability of Sertoli cells and increase p-ERK1/2 and p-JNK. Cell apoptosis in SP600125 + DBP group was significantly lower than in DBP group (P < 0.05). p-JNK was not significantly decreased in SP600125 + DBP group, while p-ERK1/2 was significantly decreased in U0126 + DBP group. CONCLUSIONS: These results suggest that DBP can lead to testicular damage and the activation of ERK1/2 and JNK pathways, the JNK signaling pathway may be primarily associated with its effect.
Descritores: Testículo/lesões
Testículo/metabolismo
Transdução de Sinais/fisiologia
Proteínas Quinases Ativadas por Mitógeno/metabolismo
Sistema de Sinalização das MAP Quinases/fisiologia
Proteínas Quinases JNK Ativadas por Mitógeno/metabolismo
Dibutilftalato/farmacologia
-Testículo/efeitos dos fármacos
Ratos Sprague-Dawley
Proteínas Quinases Ativadas por Mitógeno/fisiologia
Proteínas Quinases JNK Ativadas por Mitógeno/fisiologia
Limites: Animais
Masculino
Ratos
Responsável: CL1.1 - Biblioteca Central


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Costa, E. P
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Id: biblio-1128724
Autor: Silva, J. M; Costa, E. P; Muraro, L. S; Rego, F. C. A; Gasparini, M. J; Soares, L. C. M; Lopes, F. G; Santos, M. D.
Título: Efeito de diferentes concentrações de ingestão de gossipol livre sobre morfometria testicular e qualidade seminal de touros da raça Nelore / Effect of free gossypol intake in different levels on the testicular morphometry and seminal quality of Nelore bulls
Fonte: Arq. bras. med. vet. zootec. (Online);72(3):673-680, May-June, 2020. ilus, tab.
Idioma: pt.
Resumo: A cotonicultura tem forte fator de impacto na economia nacional, e o estado de Mato Grosso se destaca por ser o maior produtor de algodão herbáceo e deter o maior rebanho bovino do país, condições essas que estimulam o uso do caroço, da torta e do farelo de algodão na alimentação animal. Considerando que o gossipol está presente nos subprodutos do algodão e que seus efeitos sobre a reprodução podem reduzir a fertilidade dos animais, objetivou-se, com essa pesquisa, avaliar o efeito da ingestão de dietas com diferentes teores de gossipol livre por dia sobre a morfometria testicular e a qualidade seminal de touros da raça Nelore. Foram utilizados 28 touros, distribuídos aleatoriamente em seis tratamentos: T0, 0 grama de gossipol livre/touro/dia ; T1, 1,08 grama de gossipol livre/touro/dia; T2, 2,07 gramas de gossipol livre/touro/dia; T3, 3,24 gramas de gossipol livre/touro/dia; T4, 3,82 gramas de gossipol livre/touro/dia e T5, 5,08 gramas de gossipol livre/touro/dia. Os animais de cada tratamento foram mantidos confinados em área média de 100m2, dotada de bebedouro, cochos para mistura mineral e para volumoso/concentrado. O consumo de 3,24 gramas de gossipol livre/touro/dia alterou a qualidade espermática e a morfometria testicular de touros.(AU)

The cotton industry has a strong impact factor in the Brazilian economy and the state of Mato Grosso stands out for being the largest upland-type cotton producer and also holds the largest cattle herd in the country, conditions that stimulate the use of cottonseed pie and cottonseed meal in animal feed. Whereas gossypol is present in cotton by-products and their effects on reproduction can reduce the animal fertility, this research evaluated the effect of diets with different free gossypol contents in the testicular morphometry and semen quality of Nelore bulls. 28 bulls were randomly distributed in six treatments: T0, receiving no free gossypol; T1, receiving 1.08g / bull / day; T2, receiving 2.07g / bull / day; T3, receiving 3.24g / bull / day; T4, receiving 3.82g / bull / day and T5, receiving 5.08g / bull / day of free gossypol respectively. The animals in each treatment were kept confined in an averaged area of 100m2, having fresh water, troughs for mineral mixture and roughage / concentrate. The consumption of 3.24g of free gossypol / bull / day altered the bulls sperm quality and testicular morphometry.(AU)
Descritores: Testículo/anatomia & histologia
Óleo de Sementes de Algodão/administração & dosagem
Gossipol/administração & dosagem
Análise do Sêmen
Infertilidade Masculina/veterinária
Limites: Animais
Masculino
Bovinos
Responsável: BR68.1 - Biblioteca Virginie Buff D'Ápice



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