||Esquisatto, Marcelo Augusto Marretto; Joazeiro, Paulo Pinto; Pimentel, Edson Rosa; Gomes, Laurecir.|
||Ultrastructural characteristics of tensional regions in tendons from rats of different ages|
||Braz. j. morphol. sci = Rev. bras. ciênc. morfol;20(2):109-114, May-Aug. 2003. ilus.
||The calcaneal tendon and the deep digital flexor tendon are collagen-rich structures which are adapted to resist tensile stress. Since during aging tendons undergo modifications in their mechanical properties and in collagen aggregation, an understanding of the structural changes involved is important. In this work, the structural organization of the tensile region of the calcaneal and deep difital flexor tendons was studied in male Wistar rats 30, 180 and 730 days old. Large quantities of rough endoplasmic reticulum and peripheral secretory microvesicles were observed in the calcaneal tendon of 30-day-old rats. In the case of the deep digital flexor tendon, this organelle remained well-developed up to 180 days. A marked decrease in rough endoplasmic reticulum was observed in both tendons in 730-day-old rats. Proteoglycans associated with collagen fibrils were visible in the two tendons of all age groups. The reduced amount of rough endoplasmic reticulum and secretory microvesicles may be correlated with the known lower turnover of extracellular matrix components during aging.|
Fibras de Estresse
Tendão do Calcâneo/fisiopatologia
Tendão do Calcâneo/ultraestrutura
||BR734.1 - Biblioteca Central Cesar Lattes - BCCL|