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Base de dados : LILACS
Pesquisa : A13.895 [Categoria DeCS]
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Id: biblio-1011438
Autor: Ardila, Marlon Mauricio; Carrillo-Bonilla, Lina; Pabón, Adriana; Robledo, Sara M..
Título: Surveillance of phlebotomine fauna and Didelphis marsupialis (Didelphimorphia: Didelphidae) infection in an area highly endemic for visceral leishmaniasis in Colombia / Vigilancia de la fauna flebotomínea e infección de Didelphis marsupialis (Didelphimorphia: Didelphidae) en un área de alta endemia de leishmaniasis visceral en Colombia
Fonte: Biomédica (Bogotá);39(2):252-264, ene.-jun. 2019. tab, graf.
Idioma: en.
Resumo: Abstract Introduction: The study of the interaction between the parasite, the vector and the mammalian hosts, including man, allows to understand the behavior of the leishmaniases. Objective: To determine the presence of Lutzomyia species and to detect the Leishmania infection in Didelphis marsupialis in an endemic area for visceral leishmaniasis. Materials and methods: Phlebotomine fauna and individuals of D. marsupialis were collected with CDC and Tomahawk™ traps, respectively. The species of Lutzomyia were identified using the Young and Duncan key (1994). Ear and tail biopsies and blood samples from D. marsupialis were taken to identify the Leishmania species by amplifying a fragment of the gene associated with the 70 kD heat shock protein. Results: Seven Lutzomyia species were identified: Lu. evansi, Lu. gomezi, Lu. panamensis, Lu. dubitans, Lu. cayennensis cayennensis, Lu. rangeliana and Lu. trinidadensis. The first three species have epidemiological importance in Colombia because of their implications in the transmission of the Leishmania parasite. Sixty-five tissue samples from 19 D. marsupialis individuals were negative for Leishmania spp. Conclusions: The presence of the Lutzomyia species that have been identified as vectors for Leishmania inside and around houses in the village of El Bledo, in El Carmen de Bolívar represents a risk of infection. Furthermore, the presence of Lu. panamensis is reported for first time in El Carmen de Bolívar in Colombia. Although the lack of detection of Leishmania spp. in D. marsupialis samples may suggest that D. marsupialis does not play an important role in the transmission cycle of Leishmania in this region, it is necessary to carry out further longitudinal studies to confirm this hypothesis.

Resumen Introducción. El estudio de la interacción entre el parásito, el vector y los huéspedes mamíferos, incluido el hombre, permite entender el comportamiento de la leishmaniasis. Objetivo. Determinar la presencia de especies del género Lutzomyia y detectar la infección por Leishmania spp. en Didelphis marsupialis en un área endémica de leishmaniasis visceral. Materiales y métodos. Se recolectaron flebotomíneos y D. marsupialis con trampas CDC y Tomahawk™, respectivamente. Las especies de Lutzomyia se identificaron usando la clave de Young y Duncan, 1994. Se tomaron biopsias de oreja, cola y muestras de sangre de D. marsupialis para diagnosticar Leishmania spp. mediante la amplificación de un fragmento del gen de la proteína de choque térmico de 70 kD. Resultados. Se identificaron siete especies de Lutzomyia: Lu. evansi, Lu. gomezi, Lu. panamensis, Lu. dubitans, Lu. cayennensis cayennensis, Lu. rangeliana y Lu. trinidadensis. Las tres primeras especies son reconocidas como vectores en el país por estar implicadas en la transmisión de Leishmania spp. En total, 65 muestras de tejidos de oreja, cola y de sangre provenientes de 19 D. marsupialis fueron negativas para Leishmania spp. en la PCR-HSP70. Conclusiones. La presencia de flebotomíneos con importancia epidemiológica en la zona evaluada representa un riesgo de transmisión. Asimismo, Lu. panamensis es reportada por primera vez en El Bledo (Carmen de Bolívar). La ausencia de Leishmania spp. en D. marsupialis podría sugerir que esta especie no tiene un papel importante en el ciclo de transmisión de Leishmania en la vereda El Bledo, por lo que es necesario profundizar en estudios longitudinales para corroborar esta hipótesis.
Descritores: Psychodidae
Reservatórios de Doenças/parasitologia
Didelphis
Insetos Vetores
Leishmaniose Visceral/epidemiologia
-Psychodidae/parasitologia
População Rural
Especificidade da Espécie
Cauda/parasitologia
Sangue/parasitologia
Colômbia/epidemiologia
Proteínas de Choque Térmico HSP70/genética
Doenças Endêmicas
Didelphis/parasitologia
Orelha Externa/parasitologia
Habitação
Insetos Vetores/parasitologia
Leishmania/isolamento & purificação
Leishmania/classificação
Leishmania/genética
Leishmaniose Visceral/transmissão
Limites: Adolescente
Adulto
Idoso
Animais
Criança
Pré-Escolar
Feminino
Humanos
Masculino
Pessoa de Meia-Idade
Adulto Jovem
Responsável: BR1.1 - BIREME


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Id: lil-750650
Autor: Xu, Xiaochun; Wei, Xuan; Yang, Yuxin; Niu, Wenzhi; Kou, Qifang; Wang, Xiaolong; Chen, Yulin.
Título: mRNA transcription and protein expression of PPARgamma, FAS, and HSL in different parts of the carcass between fat-tailed and thin-tailed sheep
Fonte: Electron. j. biotechnol;18(3):215-220, May 2015. ilus, graf, tab.
Idioma: en.
Projeto: National Special Research Fund for Non-profit Sector; . China Agriculture Research System.
Resumo: Background The objective of this study was to compare the level differences of mRNA transcription and protein expression of PPARγ, FAS and HSL in different parts of the carcass in different tail-type sheep. Six Tan sheep and six Shaanbei fine-wool sheep aged 9 months were slaughtered and samples were collected from the tail adipose, subcutaneous adipose, and longissimus dorsi muscle. The levels of mRNA transcription and protein expression of the target genes in these tissues were determined by real-time quantitative PCR and western blot analyses. Results The results showed that PPARγ, FAS, and HSL were expressed with spatial differences in tail adipose, subcutaneous adipose and longissimus dorsi muscle of Tan sheep and Shaanbei fine-wool sheep. Differences were also observed between the two breeds. The mRNA transcription levels of these genes were somewhat consistent with their protein expression levels. Conclusion The present results indicated that PPARγ, FAS and HSL are correlated with fat deposition, especially for the regulating of adipose deposition in intramuscular fat, and that the mRNA expression patterns are similar to the protein expression patterns. The mechanism requires clarification in further studies.
Descritores: Ovinos
Esterol Esterase/genética
PPAR gama/genética
Ácido Graxo Sintases/genética
-Cauda
Transcrição Genética
RNA Mensageiro
Western Blotting
Esterol Esterase/metabolismo
PPAR gama/metabolismo
Ácido Graxo Sintases/metabolismo
Reação em Cadeia da Polimerase em Tempo Real
Limites: Animais
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-1223233
Autor: Zeng, Jie; Zhou, Shiwei; Yang, Yuxin; Du, Junli; Kang, Danju; Wang, Xiaolong; Chen, Yulin.
Título: Effect of dietary nutrition on tail fat deposition and evaluation of tail-related genes in fat-tailed sheep
Fonte: Electron. j. biotechnol;46:30-37, jul. 2020. tab, graf.
Idioma: en.
Projeto: Tan Sheep Breeding Project of Ningxia; . China Agriculture Research System.
Resumo: BACKGROUND: The effects of dietary nutrition on tail fat deposition and the correlation between production performance and the Hh signaling pathway and OXCT1 were investigated in fat-tailed sheep. Tan sheep were fed different nutritional diets and the variances in tail length, width, thickness and tail weight as well as the mRNA expression of fat-related genes (C/EBPα, FAS, LPL, and HSL) were determined in the tail fat of sheep at three different growth stages based on their body weight. Furthermore, the correlations between tail phenotypes and the Hedgehog (Hh) signaling pathway components (IHH, PTCH1, SMO, and GLI1) and OXCT1 were investigated. RESULTS: C/EBPα, FAS, LPL, and HSL were expressed with differences in tail fat of sheep fed different nutritional diets at three different growth stages. The results of the two-way ANOVA showed the significant effect of nutrition, stage, and interaction on gene expression, except the between C/EBPα and growth stage. C/EBPα, FAS, and LPL were considerably correlated with the tail phenotypes. Furthermore, the results of the correlation analysis demonstrated a close relationship between the tail phenotypes and Hh signaling pathway and OXCT1. CONCLUSIONS: The present study demonstrated the gene-level role of dietary nutrition in promoting tail fat deposition and related tail fat-related genes. It provides a molecular basis by which nutritional balance and tail fat formation can be investigated and additional genes can be identified. The findings of the present study may help improve the production efficiency of fat-tailed sheep and identify crucial genes associated with tail fat deposition.
Descritores: Cauda/metabolismo
Ovinos/genética
Tecido Adiposo
Dieta
-Fenótipo
RNA Mensageiro
Coenzima A-Transferases
Expressão Gênica
Distribuição da Gordura Corporal
Adipogenia
Lipogênese/genética
Proteínas Hedgehog/genética
Reação em Cadeia da Polimerase em Tempo Real
Limites: Animais
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-976434
Autor: Silva, Diego M; Miguel, Gabriela G. P; Souza, Michelli L; Cleveland, Herbert P. K; Ramos, Carlos A. N.
Título: Malformation of the tail in Labrador Retriever dogs caused by mutation C189G in the T gene / Malformação da cauda em cães da raça Labrador Retriever causada por mutação C189G no gene T
Fonte: Pesqui. vet. bras = Braz. j. vet. res;38(12):2237-2240, dez. 2018. graf, ilus.
Idioma: en.
Projeto: Universidade Federal de Mato Grosso do Sul.
Resumo: The present study reported the mutation C189G in the T gene (Brachyury gene) as the cause of malformation in the tail of the Labrador dog. One litter of Labradors, from a mating between a female with short tail and a male with normal tail admitted at the Veterinary Teaching Hospital of Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil, was evaluated in this study. Blood samples were collected from the female and her puppies. After DNA extraction, sequencing and PCR-RFLP were carried out. The C189G mutation was identified through both techniques only in dogs with short tail.(AU)

No presente trabalho relata-se a mutação C189G no gene T (Brachyury gene) como causa da malformação da cauda em cães da raça Labrador. Uma ninhada de labradores, provenientes do acasalamento entre uma fêmea com a cauda curta e um macho com a cauda normal, encaminhados ao Hospital Veterinário da Universidade Federal de Mato Grosso do Sul, Campo Grande, Brasil, foi avaliada nesse estudo. Amostras de sangue da cadela e filhotes foram coletadas. Após extração de DNA, sequenciamento e PCR-RFLP foram realizados. A mutação C189G foi identificada por meio de ambas as técnicas apenas nos cães com a cauda malformada.(AU)
Descritores: Cauda/anormalidades
Cães/anormalidades
Técnicas de Genotipagem/veterinária
Limites: Animais
Cães
Responsável: BR1.1 - BIREME


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Id: biblio-910172
Autor: Polidoro, D; Corrêa, L. F. D; Santos, R. P; Aiello, G; Chaves, R. O; Baumhardt, R; Ripplinger, A; Mazzanti, A.
Título: Extrusão de disco intervertebral caudal (coccígea) em um Basset Hound: primeiro relato de caso / First report of caudal intervertebral disk extrusion in a Basset Hound
Fonte: Arq. bras. med. vet. zootec. (Online);69(6):1485-1490, nov.-dez. 2017. ilus.
Idioma: pt.
Resumo: Relata-se o primeiro caso no Brasil de doença do disco intervertebral (Hansen tipo I) entre as vértebras caudais (coccígeas) em uma cadela Basset Hound com seis anos de idade, castrada, pesando 16kg e com histórico de dor durante defecação e manipulação da região pélvica associada à inabilidade de mover, elevar ou abanar a cauda. Na radiografia simples, observou-se opacidade do forame intervertebral entre a quarta e a quinta vértebra caudal. O animal foi submetido à laminectomia dorsal modificada, seguida de fenestração do disco intervertebral afetado. Decorridos 15 dias da cirurgia, a paciente não demonstrava sinais de dor ao defecar e realizava movimentos de abano de cauda, mas ainda com desconforto na palpação e sem elevação da cauda acima da coluna vertebral, o que foi resolvido após 30 dias do procedimento cirúrgico. A relevância do caso está na inclusão, mesmo que rara, da doença do disco intervertebral caudal no diagnóstico diferencial em cães com dor durante a defecação e manipulação da cauda, sendo o exame radiográfico uma ferramenta auxiliar importante para o diagnóstico definitivo e o plano terapêutico.(AU)

We report here the first case in Brazil of an intervertebral disc disease (Hansen type I) between the caudal vertebrae (coccygeal) in a six-year-old Basset Hound dog, castrated, weighing 16 kg and history of pain during defecation and manipulation of the pelvic region, associated with the inability to move, raise and shake its tail. In the radiography survey, an opacity of the intervertebral foramen between the fourth and fifth caudal vertebra was observed. The animal underwent a modified dorsal laminectomy followed by fenestration of the affected intervertebral disc. After 15 days following surgery, the patient showed no signs of pain when defecating and was able to perform the tail wag movements, but with discomfort on palpation and could not rise the tail high up the spine, which was resolved after 30 days of surgery. The relevance of this report is the inclusion, even if rare, of the caudal intervertebral disc disease in the differential diagnosis in dogs with pain during defecation and handling of the tail, and the radiographic survey is an important auxiliary tool for definitive diagnosis and treatment plan for this disease.(AU)
Descritores: Disco Intervertebral/cirurgia
Região Sacrococcígea/cirurgia
Cauda/cirurgia
-Laminectomia/veterinária
Limites: Animais
Cães
Responsável: BR68.1 - Biblioteca Virginie Buff D'Ápice


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Id: biblio-829321
Autor: Neira, Ronaldo Hertel; Estruc, Thais M; Nascimento, Renata M; Santos-Sousa, Carlos A; Souza-Junior, Paulo de; Abidu-Figueiredo, Marcelo.
Título: Origem e principais ramificações das artérias mesentéricas cranial e caudal em avestruz (Struthio camelus Linnaeus, 1758) / Origin and main ramifications of the cranial and caudal mesenteric arteries in ostrich (Struthio camelus Linnaeus, 1758)
Fonte: Pesqui. vet. bras = Braz. j. vet. res;36(9):912-918, set. 2016. tab, graf, ilus.
Idioma: pt.
Resumo: As artérias mesentéricas das aves são importantes para a irrigação do aparelho digestório e encontram-se associadas ao ganho de peso e conversão alimentar. Objetivou-se descrever as origens, esqueletopias, medidas e principais ramificações das artérias mesentéricas cranial e caudal em avestruzes. Foram utilizados 41 cadáveres de filhotes de avestruzes, 23 machos e 18 fêmeas, obtidos de um criadouro após morte natural. Os cadáveres foram fixados com formaldeído a 10% e tiveram o sistema vascular preenchido com Petrolatex® S-65 colorido. As artérias mesentéricas, cranial e caudal e seus ramos proximais foram dissecados "in situ" e medidas com paquímetro digital. A artéria mesentérica cranial teve comprimento médio de 3,68 ± 1,04 cm e surgiu da aorta descendente ao nível da oitava vértebra torácica na maioria dos casos. Ramificou-se em artérias jejunal e ileocecal. A artéria jejunal ofereceu média de 14,04 ±2,08 ramos ao jejuno e a artéria ileocecal originou um ramo retal e outro que se bifurcou para derivar ramos para íleo, ceco e reto. Em um espécime macho a artéria ileocecal foi ramo da artéria celíaca. A artéria mesentérica caudal originou-se na porção terminal da aorta descendente predominantemente ao nível das 4ª e 6ª vértebras sacro-caudais. Perto da extremidade caudal do rim emitiu os ramos cranial e caudal. O primeiro irrigou o reto e anastomosou-se com ramo retal da artéria mesentérica cranial; o segundo irrigou a porção final do reto, cloaca e bolsa cloacal. Não houve diferença significativa (p<0,05) entre as medidas, esqueletopia e número de ramificações das artérias entre os sexos.(AU)

The mesenteric arteries of birds are important for the irrigation of the digestive tract and are associated with weight gain and food conversion. This study aimed to describe the origins, skeletopy, measures and main branches of cranial and caudal mesenteric arteries in ostriches. Forty-one cadavers of ostrich chicks, 23 males and 18 females, obtained from a farmer after natural death. The cadavers were fixed with 10% formaldehyde solution and their vascular system was filled with colored Petrolatex® S-65. The cranial and caudal mesenteric arteries and its proximal branches were dissected in situ and measured with a digital caliper. The mesenteric artery had an average length of 3.68cm±1.04 and emerged from the descending aorta at the level of the eighth thoracic vertebra in most cases; it branched into jejunal and ileocecal arteries. The jejunal artery sent a mean of 14 (14.04±2.08) branches to the jejunum. The ileocecal artery sent a rectal branch and another branch that irrigated ileum, cecum and rectum. In a male specimen the ileocecal artery was originated from the celiac artery. The caudal mesenteric artery emerged in the terminal portion of the descending aorta predominantly at the level of the 4th and 6th sacrocaudal vertebrae. Near the caudal end of the kidney it issued the cranial and caudal branches. The first irrigated the rectum and anastomosed with the rectal branch of the cranial mesenteric artery; the second irrigated the final part of the rectum, cloaca and cloacal bursa. There was no significant difference (p<0.05) between measurements, skeletopy and number of branches of the arteries between genders.(AU)
Descritores: Intestinos/irrigação sanguínea
Artérias Mesentéricas/anatomia & histologia
Crânio/irrigação sanguínea
Struthioniformes/anatomia & histologia
Cauda/irrigação sanguínea
-Sistema Cardiovascular/anatomia & histologia
Limites: Animais
Responsável: BR1.1 - BIREME


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Volpon, José Batista
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Id: lil-767595
Autor: Santiago, Hildemberg Agostinho Rocha de; Pierro, Lucas Rodolfo De; Reis, Rafael Menezes; Caluz, Antônio Gabriel Ricardo Engracia; Ribeiro, Victor Barbosa; Volpon, José Batista.
Título: Allometric relationships among body mass, MUZZLE-tail length, and tibia length during the growth of Wistar rats1
Fonte: Acta cir. bras;30(11):743-748, Nov. 2015. tab, graf.
Idioma: en.
Resumo: PURPOSE : To investigate allometric relationships among body mass (BM), muzzle-tail length (MTL), and tibia length (TL) in Wistar rats and establish their growth rate change parameters. METHODS : Eighteen male and 18 female Wistar rats were studied from the 3rd to the 21st week of age. BM, MTL, and TL were measured daily, and relative growth was compared using allometry. RESULTS : A positive correlation between BM and MTL (p<0.05) and BM and TL (p<0.05) was observed. Males and females showed comparable curves; however, females had turning points at a younger age. The allometric relationship between BM and MTL presented a regular increase until reaching a mass of 351 g (males) and 405 g (females). BM and TL showed an initial increase until 185 g (males) and 182 g (females), and then reached a plateau that finished at 412 g (males) and 334 g (females), to display another increase. CONCLUSIONS : The allometric relationship of body mass with animal length and tibia length was comparable for male and female rats, with female rats maturing earlier. Animal longitudinal growth occurred in a single stage. In contrast, tibia length depicted two stages of accelerated growth with an intermediate period of deceleration.
Descritores: Tamanho Corporal/fisiologia
Peso Corporal/fisiologia
Ratos Wistar/crescimento & desenvolvimento
Cauda/crescimento & desenvolvimento
Tíbia/crescimento & desenvolvimento
-Fatores Etários
Padrões de Referência
Fatores Sexuais
Fatores de Tempo
Cauda/anatomia & histologia
Tíbia/anatomia & histologia
Limites: Animais
Feminino
Masculino
Responsável: BR1.1 - BIREME


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Id: lil-753909
Autor: Figueiredo, S I S; Araújo, E G; Araújo, L B M; Ferraz, R H S.
Título: Bases ósseas e musculares dos cortes comerciais da cauda de jacaré-do-Pantanal (Caiman yacare Daudin 1802) / Bone and muscular bases of commercial cuts from the Yacare Caiman (Caiman yacare, Daudin 1802) tail
Fonte: Arq. bras. med. vet. zootec;67(3):909-917, May-Jun/2015. graf.
Idioma: pt.
Resumo: A exploração comercial de jacaré-do-Pantanal (Caiman yacare) constitui importante cadeia produtiva no Estado de Mato Grosso. As características nutricionais e representatividade na massa corporal de crocodilianos tornaram a região da cauda objeto de estudos morfofisiológicos, evolutivos e tecnológicos. Como inexiste a caracterização anatômica dos músculos e ossos que constituem os cortes comerciais dessa região, objetivou-se descrever os músculos e correspondentes bases ósseas da cauda. Na descrição óssea, foram utilizados um exemplar adulto e seis juvenis. Para caracterização muscular, 24 espécimes juvenis foram conservados em freezer e dissecados a fresco, em ambos os antímeros, para verificação de simetria de ocorrência, fixações musculares, relacões de sintopia, forma e arquitetura muscular. As vértebras caudais são procélicas, exceto a primeira da série, e possuem na superfície ventral do corpo áreas para articulação com os processos hemais, exceto a primeira e as quatro ou cinco últimas. Os cortes comerciais da região são o filé de cauda, composto pelos músculos semiespinhal caudal, longuíssimo caudal, ilioisquiocaudal, caudofemoral longo, transverso e profundo da cauda, enquanto o corte ponta de cauda é constituído pelos músculos longuíssimo caudal e ilioisquiocaudal, com as cinco ou seis últimas vértebras caudais.

The commercial exploitation of the Yacare Caiman (Caiman yacare) has become a relevant commodity in the state of Mato Grosso, Brazil. Crocodilian's tail muscles nutritional characteristics and representativeness in body mass became the object of morphophysiological technological and evolutionary studies. The aim of this research was to report, for the first time, the anatomical characterization of muscle and bone bases of Pantanal Caiman meat cuts obtained from the tail. To describe the bones, we used one adult and six juvenile specimens of Pantanal Caiman. In order to study the muscle, 24 juvenile individuals were slaughtered and skinned, preserved in a -20oC freezer and thawed at the time of use, without any fixation. After evisceration, the specimens were dissected on both sides to verify structural symmetry, muscle attachments, sintopy relations, shape and muscular architecture. Caudal vertebrae are procoelous, except for the first of the series, and have sites on the ventral surface of their body where the hemal processes articulate, with the exception of the first and the last four or five vertebrae. The commercial meat cuts of the tail are the tail sirloin, composed of semispinal caudal, longissimus caudal, ilioischiocaudal, long caudofemoral, transverse and deep of the tail muscles, and also the tail tip, consisting of the longissimus caudal and ilioischiocaudal muscles, based on the last five or six caudal vertebrae.
Descritores: Cauda/anatomia & histologia
Jacarés e Crocodilos/anatomia & histologia
Músculos/anatomia & histologia
Osso e Ossos/anatomia & histologia
-Carne/classificação
Limites: Animais
Responsável: BR68.1 - Biblioteca Virginie Buff D'Ápice


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Id: lil-595722
Autor: Bessa, K. L; Belletati, J. F; Santos, L. dos; Rossoni, L. V; Ortiz, J. P.
Título: Drag reduction by polyethylene glycol in the tail arterial bed of normotensive and hypertensive rats
Fonte: Braz. j. med. biol. res = Rev. bras. pesqui. méd. biol;44(8):767-777, Aug. 2011. ilus.
Idioma: en.
Resumo: This study was designed to evaluate the effect of drag reducer polymers (DRP) on arteries from normotensive (Wistar) and spontaneously hypertensive rats (SHR). Polyethylene glycol (PEG 4000 at 5000 ppm) was perfused in the tail arterial bed with (E+) and without endothelium (E-) from male, adult Wistar (N = 14) and SHR (N = 13) animals under basal conditions (constant flow at 2.5 mL/min). In these preparations, flow-pressure curves (1.5 to 10 mL/min) were constructed before and 1 h after PEG 4000 perfusion. Afterwards, the tail arterial bed was fixed and the internal diameters of the arteries were then measured by microscopy and drag reduction was assessed based on the values of wall shear stress (WSS) by computational simulation. In Wistar and SHR groups, perfusion of PEG 4000 significantly reduced pulsatile pressure (Wistar/E+: 17.5 ± 2.8; SHR/E+: 16.3 ± 2.7 percent), WSS (Wistar/E+: 36; SHR/E+: 40 percent) and the flow-pressure response. The E- reduced the effects of PEG 4000 on arteries from both groups, suggesting that endothelial damage decreased the effect of PEG 4000 as a DRP. Moreover, the effects of PEG 4000 were more pronounced in the tail arterial bed from SHR compared to Wistar rats. In conclusion, these data demonstrated for the first time that PEG 4000 was more effective in reducing the pressure-flow response as well as WSS in the tail arterial bed of hypertensive than of normotensive rats and these effects were amplified by, but not dependent on, endothelial integrity. Thus, these results show an additional mechanism of action of this polymer besides its mechanical effect through the release and/or bioavailability of endothelial factors.
Descritores: Hipertensão/fisiopatologia
Polietilenoglicóis/farmacologia
Cauda/irrigação sanguínea
Resistência Vascular/efeitos dos fármacos
-Artérias/efeitos dos fármacos
Artérias/fisiologia
Velocidade do Fluxo Sanguíneo/efeitos dos fármacos
Viscosidade Sanguínea/efeitos dos fármacos
Endotélio Vascular/efeitos dos fármacos
Endotélio Vascular/fisiologia
Modelos Animais
Ratos Endogâmicos SHR
Ratos Wistar
Resistência Vascular/fisiologia
Limites: Animais
Masculino
Ratos
Tipo de Publ: Estudo de Avaliação
Research Support, Non-U.S. Gov't
Responsável: BR1.1 - BIREME


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Id: lil-578298
Autor: O'Connor, Patrick M; Sertich, Joseph J. W; Manthi, Fredrick K.
Título: A pterodactyloid pterosaur from the Upper Cretaceous Lapurr sandstone, West Turkana, Kenya
Fonte: An. acad. bras. ciênc;83(1):309-315, Mar. 2011. ilus.
Idioma: en.
Conferência: Apresentado em: Gondwanan Dinosaur Symposium, Third,
Resumo: An isolated pterosaurian caudal cervical (~ postcervical) vertebra was recovered from the Upper Cretaceous Lapurr sandstone ofWest Turkana, northwestern Kenya. The vertebral centrum is short, wide, and dorsoventrally compressed. Although the specimen is lightly built similar to most pterosaurs, it is here referred to Pterodactyloidea and tentatively to the Azhdarchidae in that it lacks pneumatic features on both the centrum and neural arch. This represents one of the few pterosaurs recovered from the entirety of Afro-Arabia, the first pterosaur recovered from the Cretaceous of East Africa, and, significantly, a specimen that was recovered from fluvial deposits rather than the near-shore marine setting typical of most pterosaur discoveries.

Uma vértebra cervical caudal isolada de pterossauro (~ pós-cervical) foi recuperada do Cretáceo Superior do arenito de Lapurr do Oeste de Turkana, noroeste do Quênia. O centro vertebral é curto, largo e comprimido dorsoventralmente. Embora o espécime seja leve como grande parte dos pterossauros, ele é aqui referido a Pterodactyloidea e tentativamente a Azhdarchidae no que diz respeito à ausência de características pneumáticas tanto no centro quanto no arco neural. Este representa um dos poucos pterossauros recuperados do conjunto Afro-Arábia, o primeiro pterossauro proveniente do Cretáceo do Leste da África e, significativamente, um espécime que foi recuperado de depósitos fluviais e não do cenário marinho próximo da costa típico da maioria das descobertas de pterossauros.
Descritores: Vértebras Cervicais/anatomia & histologia
Dinossauros/anatomia & histologia
Dinossauros/classificação
Fósseis
Cauda/anatomia & histologia
-Brasil
Quênia
Limites: Animais
Tipo de Publ: Research Support, Non-U.S. Gov't
Responsável: BR1.1 - BIREME



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