Base de dados : LILACS
Pesquisa : B01.050.150.900.649.313.992.635.075.250 [Categoria DeCS]
Referências encontradas : 541 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 55 ir para página                         

  1 / 541 LILACS  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: lil-732518
Autor: Maia, Andréa Casa Nova.
Título: Outro inferno de Dante numa mina de ouro na época de Vargas: Nova Lima, Minas Gerais / Another Dante's inferno in a gold mine during the Vargas era: Nova Lima, Minas Gerais
Fonte: Hist. ciênc. saúde-Manguinhos;21(4):1197-1214, Oct-Dec/2014.
Idioma: pt.
Resumo: O artigo analisa as estratégias de controle existentes no trabalho na mina de Morro Velho, Minas Gerais, e as mudanças resultantes da implementação da legislação trabalhista durante o governo Vargas. Discute as doenças causadas pelo trabalho na mina, silicose e arsenicismo, através de depoimentos de ex-mineiros e do livro de um autor anônimo que aborda as doenças e as relações de poder entre patrões e empregados, apontando os limites da legislação e das lutas operárias. O livro traz um depoimento contundente de como a empresa proprietária, inglesa, burlou, durante muito tempo, leis como a da taxa de insalubridade. Direito que outras mineradoras, não só de propriedade inglesa, costumavam e até hoje costumam desrespeitar pelo mundo.

This article analyzes the control strategies in place at Morro Velho mine in the Brazilian state of Minas Gerais, and the changes after the implementation of labor legislation during the Vargas administration. The diseases common amongst mine workers, silicosis and arsenicosis, are investigated through statements given by former miners and a book by an anonymous author that discusses the diseases and the power relations between employers and employees, identifying the limitations of the legislation and the workers’ struggles. The book presents a striking story of how for many years the British company side-stepped laws such as the insalubrity premium, a right which other mining companies, not only of British ownership, flouted and still flout in different parts of the world.
Descritores: Dano ao DNA
Testes de Mutagenicidade/métodos
-Linhagem Celular
Sobrevivência Celular/efeitos dos fármacos
Sobrevivência Celular/genética
Eletroforese em Gel de Poliacrilamida
Mentol/toxicidade
Nitrofenóis/toxicidade
Sarcosina/análogos & derivados
Sarcosina/toxicidade
Limites: Humanos
Animais
Cricetinae
Responsável: BR1.1 - BIREME


  2 / 541 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-1001897
Autor: Juanes, Camila de Carvalho; Souza, Susana Moreira de; Braga, Vanessa Nogueira Lages; Barreto, Francisco Stefânio; Aguiar, Gisele Rocha; Pimentel, Kleison Douglas Gomes; Fechine, Francisco Vagnaldo; Dornelas, Conceição Aparecida.
Título: Red propolis and L-lysine on angiogenesis and tumor growth in a new model of hamster cheek pouch inoculated with Walker 256 tumor cells / Própolis vermelha e L-lisina na angiogênese e no crescimento tumoral em novo modelo de bolsa jugal de hamster inoculada com células de tumor de Walker 256
Fonte: Einstein (Säo Paulo);17(2):eAO4576, 2019. tab, graf.
Idioma: en.
Resumo: ABSTRACT Objective: To evaluate the effect of red propolis and L-lysine on angiogenesis and tumor growth in a new model of hamster cheek pouch inoculated with Walker 256 tumor cells. Methods: The study consisted of two experiments with four groups each (total: 57 hamsters). In the experiment 1, the animals were inoculated with Walker tumor cells, followed by administration of test substances (red propolis 200mg/5mL/kg or L-lysine 150mg/kg) or control substances (gum arabic 5mL/kg or water 5mL/kg) for 10 days. The animals in the experiment 2 received red propolis, L-lysine, gum arabic or water at the same doses, for 33 days prior to inoculation of Walker tumor cells, followed by 10 days of treatment with the same substances. Based on single-plane images, angiogenesis was quantified (mean vascular area), in percentage, and tumor area (mm2) and perimeter (mm). Results: In the experiment 1, compared to animals receiving water, the mean vascular area expressed in percentage was significantly smaller in animal treated with propolis (p<0.05) and L-lysine (p<0.001). Conclusion: Both red propolis and L-lysine inhibited tumor angiogenesis in the new hamster cheek pouch model when administered after tumor inoculation.

RESUMO Objetivo: Avaliar o efeito da própolis vermelha e da L-lisina na angiogênese e no crescimento tumoral em novo modelo de bolsa jugal de hamster inoculada com células de tumor de Walker 256. Métodos: O estudo consistiu em dois experimentos com quatro grupos cada (total: 57 hamsters). No experimento 1, os animais foram inoculados com células de tumor de Walker, tendo em seguida administradas as substâncias teste (própolis vermelha 200mg/5mL/kg ou L-lisina 150mg/kg) ou controle (goma arábica 5mL/kg ou água 5mL/kg) por 10 dias. Os animais do experimento 2 receberam própolis vermelha, L-lisina, goma arábica ou água nas mesmas doses, por 33 dias antes do inóculo das células de tumor de Walker, seguido por 10 dias de tratamento com as mesmas substâncias. Baseado em imagens em plano único, foram quantificados a angiogênese (área vascular média), em termos percentuais, e a área (mm2) e o perímetro (mm) do tumor. Resultados: Comparada aos animais que receberam água, a área vascular média, expressa em percentagem, foi significativamente menor nos animais tratados com própolis (p<0,05) e com L-lisina (p<0,001). Conclusão: Tanto a própolis vermelha quanto a L-lisina inibiram a angiogênese no novo modelo de bolsa jugal de hamsters, quando administradas após a inoculação do tumor.
Descritores: Própole/uso terapêutico
Inibidores da Angiogênese/uso terapêutico
Lisina/uso terapêutico
Neovascularização Patológica/tratamento farmacológico
-Neoplasias Bucais/induzido quimicamente
Neoplasias Bucais/irrigação sanguínea
Neoplasias Bucais/tratamento farmacológico
Carcinoma 256 de Walker/irrigação sanguínea
Ganho de Peso
Bochecha
Cricetinae
Mesocricetus
Resultado do Tratamento
Modelos Animais
Antioxidantes
Responsável: BR1.1 - BIREME


  3 / 541 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
ANDRADE JUNIOR, Heitor Franco de
Texto completo
Id: lil-782098
Autor: Borborema, Samanta Etel Treiger; Osso Junior, João Alberto; Andrade Junior, Heitor Franco de; Nascimento, Nanci do.
Título: Antimonial drugs entrapped into phosphatidylserine liposomes: physicochemical evaluation and antileishmanial activity
Fonte: Rev. Soc. Bras. Med. Trop;49(2):196-203, Mar.-Apr. 2016. tab, graf.
Idioma: en.
Projeto: Conselho Nacional de Desenvolvimento Científico e Tecnológico.
Resumo: Abstract: INTRODUCTION: Leishmaniasis is a disease caused by the protozoan Leishmania that resides mainly in mononuclear phagocytic system tissues. Pentavalent antimonials are the main treatment option, although these drugs have toxic side effects and high resistance rates. A potentially alternative and more effective therapeutic strategy is to use liposomes as carriers of the antileishmanial agents. The aims of this study were to develop antimonial drugs entrapped into phosphatidylserine liposomes and to analyze their biological and physicochemical characteristics. METHODS: Liposomes containing meglumine antimoniate (MA) or pentavalent antimony salt (Sb) were obtained through filter extrusion (FEL) and characterized by transmission electron microscopy. Promastigotes of Leishmania infantum were incubated with the drugs and the viability was determined with a tetrazolium dye (MTT assay). The effects of these drugs against intracellular amastigotes were also evaluated by optical microscopy, and mammalian cytotoxicity was determined by an MTT assay. RESULTS: Liposomes had an average diameter of 162nm. MA-FEL showed inhibitory activity against intracellular L. infantum amastigotes, with a 50% inhibitory concentration (IC50) of 0.9μg/mL, whereas that of MA was 60μg/mL. Sb-FEL showed an IC50 value of 0.2μg/mL, whereas that of free Sb was 9μg/mL. MA-FEL and Sb-FEL had strong in vitro activity that was 63-fold and 39-fold more effective than their respective free drugs. MA-FEL tested at a ten-times higher concentration than Sb-FEL did not show cytotoxicity to mammalian cells, resulting in a higher selectivity index. CONCLUSIONS: Antimonial drug-containing liposomes are more effective against Leishmania-infected macrophages than the non-liposomal drugs.
Descritores: Compostos Organometálicos/farmacologia
Fosfatidilserinas/farmacologia
Macrófagos Peritoneais/parasitologia
Leishmania infantum/efeitos dos fármacos
Gluconato de Antimônio e Sódio/farmacologia
Meglumina/farmacologia
Antiprotozoários/farmacologia
-Compostos Organometálicos/química
Fosfatidilserinas/química
Cricetinae
Gluconato de Antimônio e Sódio/química
Concentração Inibidora 50
Testes de Sensibilidade Parasitária
Relação Dose-Resposta a Droga
Antimoniato de Meglumina
Lipossomos
Meglumina/química
Camundongos
Camundongos Endogâmicos BALB C
Antiprotozoários/química
Limites: Animais
Responsável: BR1.1 - BIREME


  4 / 541 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-829664
Autor: Hassan, Ehssan Ahmed; Abdel-Rahman, Mohamed Ahmed; Ibrahim, Mohamed Moussa; Soliman, Maha Farid Mohamed.
Título: In vitro antischistosomal activity of venom from the Egyptian snake Cerastes cerastes
Fonte: Rev. Soc. Bras. Med. Trop;49(6):752-757, Dec. 2016. tab, graf.
Idioma: en.
Resumo: Abstract INTRODUCTION: We studied the potential in vitro antischistosomal activity of Cerastes cerastes venom on adult Schistosoma mansoni worms. METHODS: Live specimens of the horned viper snake, C. cerastes were collected from the Aswan Governorate (Egypt). Venom was collected from snakes by manual milking. Worms of S. mansoni were obtained from infected hamsters by perfusion and isolated from blood using phosphate buffer. Mortality rates of worms were monitored after 3 days of exposure to snake venom at LC50 and various sublethal concentrations (10, 5, 2.5µg/ml). Scanning electron microscopy was used to investigate tegumental changes in treated worms after exposure to LC50 doses of venom. RESULTS: The LC50 of C. cerastes venom was 21.5µg/ml. The effect of C. cerastes venom on Schistosoma worms varied according to their sex. The mortality rate of male and female worms after 48-h exposure was 83.3% and 50%, respectively. LC50 of C. cerastes venom induced mild to severe tegumental damage in Schistosoma worms in the form of destruction of the oral sucker, shrinkage and erosion of the tegument, and loss of some tubercle spines. CONCLUSIONS: The present study demonstrated that C. cerastes venom exerts potential in vitro antischistosomal activity in a time and dose-dependent manner. These results may warrant further investigations to develop novel schistosomicidal agents from C. cerastes snake venom.
Descritores: Schistosoma mansoni/efeitos dos fármacos
Esquistossomicidas/farmacologia
Venenos de Víboras/farmacologia
-Schistosoma mansoni/ultraestrutura
Esquistossomicidas/isolamento & purificação
Fatores de Tempo
Microscopia Eletrônica de Varredura
Cricetinae
Relação Dose-Resposta a Droga
Egito
Dose Letal Mediana
Limites: Animais
Masculino
Feminino
Responsável: BR1.1 - BIREME


  5 / 541 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-842826
Autor: Mesa, Luz Estella; Vasquez, Daniel; Lutgen, Pierre; Vélez, Iván Darío; Restrepo, Adriana María; Ortiz, Isabel; Robledo, Sara María.
Título: In vitro and in vivo antileishmanial activity of Artemisia annua L. leaf powder and its potential usefulness in the treatment of uncomplicated cutaneous leishmaniasis in humans
Fonte: Rev. Soc. Bras. Med. Trop;50(1):52-60, Jan.-Feb. 2017. tab, graf.
Idioma: en.
Projeto: Departamento Administrativo de Ciencia, Tecnología e Innovación-COLCIENCIAS.
Resumo: ABSTRACT INTRODUCTION: Cutaneous leishmaniasis (CL) is a tropical disease that affects millions of individuals worldwide. The current drugs for CL may be effective but have serious side effects; hence, alternatives are urgently needed. Although plant-derived materials are used for the treatment of various diseases in 80% of the global population, the validation of these products is essential. Gelatin capsules containing dried Artemisia annua leaf powder were recently developed as a new herbal formulation (totum) for the oral treatment of malaria and other parasitic diseases. Here, we aimed to determine the usefulness of A. annua gel capsules in CL. METHODS: The antileishmanial activity and cytotoxicity of A. annua L. capsules was determined via in vitro and in vivo studies. Moreover, a preliminary evaluation of its therapeutic potential as antileishmanial treatment in humans was conducted in 2 patients with uncomplicated CL. RESULTS: Artemisia annua capsules showed moderate in vitro activity in amastigotes of Leishmania (Viannia) panamensis; no cytotoxicity in U-937 macrophages or genotoxicity in human lymphocytes was observed. Five of 6 (83.3%) hamsters treated with A. annua capsules (500mg/kg/day) for 30 days were cured, and the 2 examined patients were cured 45 days after initiation of treatment with 30g of A. annua capsules, without any adverse reactions. Both patients remained disease-free 26 and 24 months after treatment completion. CONCLUSION: Capsules of A. annua L. represent an effective treatment for uncomplicated CL, although further randomized controlled trials are needed to validate its efficacy and safety.
Descritores: Extratos Vegetais/uso terapêutico
Extratos Vegetais/farmacologia
Leishmaniose Cutânea/tratamento farmacológico
Artemisia annua/química
Antiprotozoários/uso terapêutico
Antiprotozoários/farmacologia
-Cricetinae
Resultado do Tratamento
Folhas de Planta/química
Testes de Sensibilidade Parasitária
Leishmania/efeitos dos fármacos
Limites: Humanos
Animais
Masculino
Feminino
Adulto
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


  6 / 541 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-1003127
Autor: Guerrero, Nidya Alexandra Segura; García, Felio Jesús Bello.
Título: Comparative assessment of the replication efficiency of dengue, yellow fever, and chikungunya arboviruses in some insect and mammalian cell lines
Fonte: Rev. Soc. Bras. Med. Trop;52:e20180511, 2019. graf.
Idioma: en.
Resumo: Abstract INTRODUCTION: Insect cell cultures play an essential role in understanding arboviral replication. However, the replicative efficiency of some of these viruses such as dengue (DENV), yellow fever (YFV), and chikungunya (CHIKV) in a new cellular substrate (Lulo) and in the other two recognized cell lines has not been comparatively assessed. METHODS: Vero, C6/36, and Lulo cell lines were infected with DENV, YFV, and CHIKV. The viral progeny was quantified through plaque assays and quantitative reverse transcription-polymerase chain reaction, while for DENV2, the findings were confirmed by immunofluorescence antibody assay. RESULTS: The higher DENV2 titer (from multiplicity of infection 0.001) was obtained on day four post-infection in C6/36 and on day six in Vero cells, while the Lulo cell line was almost impossible to infect under the same conditions. However, C6/36 showed the highest values of viral RNA production compared to Vero cells, while the quantification of the viral RNA in Lulo cells showed high levels of viral genomes, which had no correlation to the infectious viral particles. CONCLUSIONS: C6/36 was the most efficient cell line in the alpha and flavivirus production, followed by Vero cells. Thus, Lulo cells may be a useful substrate to study the mechanisms by which cells evade viral replication.
Descritores: Replicação Viral/fisiologia
Vírus da Febre Amarela/fisiologia
Vírus Chikungunya/fisiologia
Vírus da Dengue/fisiologia
Insetos/virologia
-Fatores de Tempo
Células Vero
Chlorocebus aethiops
Cricetinae
Reação em Cadeia da Polimerase Via Transcriptase Reversa
Limites: Animais
Tipo de Publ: Estudo Comparativo
Responsável: BR1.1 - BIREME


  7 / 541 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Camargo, Zoilo Pires de
Id: biblio-1242466
Autor: Bagagli, Eduardo; Sano, Ayako; Coelho, Kunie Iabuki; Alquati, Sislaine; Miyaji, Makoto; Camargo, Zoilo Pires de; Gomes, Galuce Mary; Franco, Marcello; Montenegro, Mario Rubens.
Título: Isolation of Paracoccidoides brasiliensis from armadillos (Dasypus novemcinctus) captured in an endemic area of paracoccidioidomycosis.
Fonte: s.l; s.n; 1998. 8 p. ilus, tab.
Idioma: en.
Resumo: Paracoccidioides brasiliensis, the causative agent of paracoccidioidomycosis (PCM), was first isolated from the Amazonian gerion where the mycosis is uncommon. In the present study, we report on the high incidence of PCM infection in armadillos from a hyperendemic region of the disease. Four nine-banded armadillos (Dasypus novemcinctus) were captured in the endemic area of Botucatu, Sao Paulo, Brazil, killed by manual cervical dislocation and autopsied under sterile conditions. Fragments of lung, spleen, liver and mesenteric lymph nodes were precessed for histology, cultured on Mycosel agar at 37ºC, and homogenized for inoculation into the testis and peritoneum of hamster. The animals were killed from week 6 to week 20 postinoculation and fragments of liver, lung, spleen, testis, and lymph nodes were cultured on brain heart infusion agar at 37ºC. Paracoccidioides brasiliensis was isolated from three armadillos both by direct organ culture and from the liver, spleen, lung, and mesenteric lymph node hamster. In addition, one positive armadillo presented histologically proven PCM disease in a mesenteric lymph node. The three aramdillos isolates (Pb-A1, Pb-A2, and Pb-A4) presented thermodependent dimorphism, urease activity, and casein assimilation, showed amplification of the gp43 gene, and were highly virulent in intratesticulary inoculation hamster. The isolates expressed the gp43 glycoprotein, the immunodominant antigen of the fungus, and reacted with a pool of sera from PCM patients. Taken together, the present data confirm that armadillos are a natural reservoir of P. brasiliensis and demonstrate that the animal is a sylvan host to the fungus
Descritores: Cricetinae/fisiologia
Cricetinae/genética
Cricetinae/imunologia
Paracoccidioidomicose/fisiopatologia
Paracoccidioidomicose/genética
Paracoccidioidomicose/imunologia
Paracoccidioidomicose/microbiologia
Tipo de Publ: Estudo Comparativo
Artigo Clássico
Responsável: BR191.1 - Biblioteca e Centro de Documentação Luiza Keffer
[{"text": "BR191.1", "_a": "09284/s"}]


  8 / 541 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
Id: biblio-1235509
Autor: Nogueira, Maria Esther Salles.
Título: Inoculaçao de Mycobacterium leprae na bolsa jugal do hamster / ?.
Fonte: Botucatu; s.n; 1999. 98 p. ilus, tab, graf.
Idioma: pt.
Tese: Apresentada a Universidade Estadual Paulista Júlio de Mesquita Filho. Faculdade de Medicina de Botucatu para obtenção do grau de Doctor.
Resumo: A utilizaçao da bolsa jugal do hamster na hanseníase experimental, foi avaliada por meio da inoculaçao de 6,0x101 8 M. leprae/ml no seu tecido subepitelial em 60 animais, empregando como grupo de controle, 12 hamster inoculados no coxim plantar. Os animais foram sacrificados 20 e 48 horas e 7, 14, 21 e 28 dias p.i. A evoluçao da lesao de inoculaçao foi anlisada pelo exame histológico em cortes corados pela hematoxilinaeosina e Faraco-Fite. A avaliçao da viabilidade bacilar na bolsa jugal do hamster foi realizada 7, 14, 21 e 28 dias p.i. pelo teste de recuperaçao dos bacilos em camundongos. Os resultados nos permitiram concluir que: a) a resposta inflamatória inicial ao M. leprae na bolsa jugal foi exsutativa e inespecífica, com duraçao curta;
Descritores: Cricetinae/anatomia & histologia
Hanseníase/microbiologia
Mycobacterium leprae/isolamento & purificação
Mycobacterium leprae/patogenicidade
Responsável: BR191.1 - Biblioteca e Centro de Documentação Luiza Keffer
[{"text": "BR191.1", "_a": "WC335.403", "_b": "N689i"}]


  9 / 541 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Arruda, Maria Sueli Parreira de
Texto completo
Id: biblio-1085451
Autor: Arruda, Maria Sueli Parreira de; Giglioli, Silvia; Vilani-Moreno, Fátima Regina.
Título: Experimental dermatophytosis in hamsters inoculated with Trichophyton mentagrophytes in the cheek pouch.
Fonte: São Paulo; s.n; 2001. 4 p. ilus.
Idioma: en.
Resumo: This study presents the results of T. mentagrophytes inoculation in the cheek pouch of the hamster, an immunologically privileged site. Forty two animals were used: 21 inoculated with 106 fungi in the cheek pouch (group 1) and 21 inoculated initially with 106 fungi in the foot pad and 15 days later in the cheek pouch, with the same amount of fungi (group 2). Animals were sacrificed at 20 hours, 3, 7, 14, 30, 60, and 120 days; samples from inoculated cheek pouch, and foot pads submitted to the foot pad test (FPT), were collected. Independent of group and time of evolution of infection, animals did not develop delayed hypersensitivity evaluated through the FPT. The pre-inoculation of fungi in the foot pad did not change the morphology of lesions induced in the cheek pouch. Therefore, in animals of group 1 and 2, the introduction of the fungus in the cheek pouch resulted in focal lesion composed of a sterile acute inflammatory infiltrate, with abscess formation that evolved to a macrophagic reaction, and later to resolution even in the absence of immune response detectable by FPT. Our results indicate that in spite of the important role of the immune response in the spontaneous regression of dermatophytosis, other factors are also an integral part in the defense against this fungal infection
Descritores: Cricetinae
Dermatomicoses/microbiologia
Trichophyton
-Dermatomicoses/patologia
Limites: Animais
Responsável: BR191.1 - Biblioteca e Centro de Documentação Luiza Keffer
BR191.1; 9458/s


  10 / 541 LILACS  
              first record previous record
seleciona
para imprimir
Fotocópia
Arruda, Maria Sueli Parreira de
Texto completo
Id: biblio-1085465
Autor: Vilani-Moreno, Fátima Regina; Arruda, Maria Sueli Parreira de; Escudero, Heloísa Helena.
Título: Candidíase experimental: estudo comparativo de dois métodos de coloração vital na determinação da viabilidade dos fungos em suspensão / Experimental candidiasis: comparative study of two vital coloration methods in fungus viability determination in suspension.
Fonte: Bauru; s.n; 1999. 4 p.
Idioma: pt.
Resumo: No presente estudo, comparou-se o percentual de viabilidade da candida albicans em suspensäo, utilizando-se dois métodos de coloraçäo vital: o azul algodäo e associaçäo entre os corantes fluorescentes diacetato de fluoresceína (DF) e brometo de etídeo (BE). A análise histológica das lesöes induzidas por precauçöes, cuja concentraçäo fúngica foi ajustada segundo cada um dos métodos, associado ao fato do percentual de célulacs vivas indicado pelo método fluorescente ser cerca de 50 por cento menor que o obtido através da coloraçäo pelo azul algodäo, sugere seu emprego ao invés da coloraçäo pelo DF- BE em estudos envolvendo a determinaçäo da viabilidade da Candida albicans em suspensäo
Descritores: Candida/patogenicidade
Candidíase/fisiopatologia
Coloração e Rotulagem/métodos
Corantes Fluorescentes
-Fungos/patogenicidade
Microscopia
Limites: Animais
Cricetinae
Tipo de Publ: Estudo Comparativo
Responsável: BR191.1 - Biblioteca e Centro de Documentação Luiza Keffer
BR191.1; 9457/s



página 1 de 55 ir para página                         
   


Refinar a pesquisa
  Base de dados : Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde