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Id: biblio-1134073
Autor: Peixoto, Cláudio de Oliveira.
Título: Saúde, ciência e desenvolvimento: a emergência da leishmaniose tegumentar americana como desafio médico-sanitário no Amazonas / Health, science and development: the emergence of American cutaneous leishmaniasis as a medical and public health challenge in Amazonas state, Brazil
Fonte: Hist. ciênc. saúde-Manguinhos;27(3):741-761, set. 2020. tab, graf.
Idioma: pt.
Resumo: Resumo O artigo faz análise histórica da emergência da leishmaniose tegumentar americana como objeto do conhecimento e desafio médico-sanitário no Amazonas desde a década de 1970. Fornece visão geral dessa época, as medidas sanitárias e os estudos científicos realizados no contexto de implantação dos principais projetos de desenvolvimento regionais executados em nome da política de integração nacional do governo federal. Utiliza como metodologia a análise documental de leis, produção científica, relatórios de pesquisa, boletins epidemiológicos e jornais. Os resultados da pesquisa mostram que a doença surgiu no Amazonas associando o grande problema de saúde com mudanças político-econômicas e alterações socioambientais.

Abstract The history of the emergence of American cutaneous leishmaniasis in the Brazilian state of Amazonas since the 1970s is analyzed as an object of knowledge and a medical and public health challenge. An overview of the period is provided, including the public health measures and scientific studies undertaken in the context of the execution of large-scale regional developments pursued in the name of national integration by the federal government. The methodology uses documental analysis of laws, the scientific literature, research reports, epidemiological bulletins, and newspapers. The results show that American cutaneous leishmaniasis emerged as a major health problem in Amazonas in close association with the political, economic, and socioenvironmental changes seen in the period.
Descritores: Saúde Pública/história
Leishmaniose Cutânea/história
Conservação dos Recursos Naturais
Leishmania/isolamento & purificação
-Psychodidae/parasitologia
Urbanização/história
Leishmania braziliensis/isolamento & purificação
Brasil/epidemiologia
Controle de Insetos/história
Leishmaniose Cutânea/transmissão
Leishmaniose Cutânea/epidemiologia
Leishmania guyanensis/isolamento & purificação
Desenvolvimento Industrial/história
Insetos Vetores
Limites: Humanos
Animais
Tipo de Publ: Artigo Histórico
Responsável: BR1.1 - BIREME


  2 / 890 LILACS  
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Marcondes, Carlos Brisola
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Id: lil-722306
Autor: Marcondes, Carlos Brisola.
Título: Defense of taxonomy, a Sisyphus task?
Fonte: Rev. Soc. Bras. Med. Trop;47(4):538-538, Jul-Aug/2014.
Idioma: en.
Descritores: Psychodidae/fisiologia
Insetos Vetores/fisiologia
Limites: Humanos
Animais
Feminino
Tipo de Publ: Comentário
Carta
Responsável: BR1.1 - BIREME


  3 / 890 LILACS  
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Id: lil-776533
Autor: Oliveira, Agda Maria; Guirado, Marluci Monteiro; Dibo, Margareth Regina; Rodas, Lilian Aparecida Colebrusco; Bocchi, Monica Regina; Chiaravalloti-Neto, Francisco.
Título: Occurrence of Lutzomyia longipalpis andhuman and canine cases of visceral leishmaniasis and evaluation of their expansion in the Northwest region of the State of São Paulo, Brazil
Fonte: Rev. Soc. Bras. Med. Trop;49(1):41-50, Jan.-Feb. 2016. graf.
Idioma: en.
Projeto: Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP).
Resumo: Abstract: INTRODUCTION This paper aims to describe the dispersion of Lutzomyia longipalpis and the autochthonous occurrence of visceral leishmaniasis (VL) in the Northwest region of the State of São Paulo between 2007 and 2013 and to analyze their expansion. METHODS Information about the vector and associated cases was described using maps. The incidence, mortality, and lethality of human visceral leishmaniasis (HVL) were calculated. In municipalities in which more than one HVL case occurred, incidences were calculated according to census sector, and spatial and spatiotemporal clusters were identified. RESULTS The first case of HVL was reported in the municipality of Jales in 2007. By 2013, the vector and the disease had expanded from west to east, with the vector being detected in 29 municipalities. A total of 11 municipalities had cases of canine visceral leishmaniasis (CVL), and six had cases of HVL. Vector expansion occurred by vicinity with previously infested municipalities, and the expansion of VL was related to the major highways and the capital municipalities of the micro-regions in the study area. The highest incidence of HVL occurred in children between 0-4 years old, and the highest mortality and lethality occurred among persons aged 60 and older. The occurrence of HLV was more intense in the peripheral areas of municipalities with the disease. CONCLUSIONS The findings of this study may be useful for improving VL surveillance and control activities by slowing VL expansion and/or mitigating VL effects when they occur.
Descritores: Psychodidae
Doenças do Cão/transmissão
Insetos Vetores
Leishmaniose Visceral/transmissão
-Brasil/epidemiologia
Incidência
Doenças do Cão/mortalidade
Análise Espaço-Temporal
Leishmaniose Visceral/mortalidade
Leishmaniose Visceral/veterinária
Pessoa de Meia-Idade
Limites: Humanos
Animais
Recém-Nascido
Lactente
Pré-Escolar
Criança
Adolescente
Adulto
Cães
Adulto Jovem
Responsável: BR1.1 - BIREME


  4 / 890 LILACS  
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Id: lil-798129
Autor: Thies, Sirlei Franck; Bronzoni, Roberta Vieira de Morais; Espinosa, Mariano Martinez; Souza, Cladson de Oliveira; Ribeiro, Ana Lucia Maria; Santos, Emerson Soares dos; Dias, Edelberto Santos; Damazo, Amílcar Sabino.
Título: Frequency and diversity of phlebotomine sand flies (diptera: psychodidae) in sinop, state of Mato Grosso, Brazil
Fonte: Rev. Soc. Bras. Med. Trop;49(5):544-552, Sept.-Oct. 2016. tab, graf.
Idioma: en.
Projeto: Fundação de Amparo à Pesquisa em Mato Grosso.
Resumo: Abstract INTRODUCTION: Understanding the diversity of sand flies is important for the epidemiology and control of leishmaniasis. This study aimed to understand the frequency, diversity, and seasonality of medically important sand flies in the municipality of Sinop, State of Mato Grosso, Brazil. METHODS: The study was conducted in an urban area, including four ecotypes with different levels of urbanization. The sand flies were collected using light traps for three nights per month, from May 2014 to April 2015. RESULTS: A total of 62,745 sand flies was collected, 52.34% of which were female. The frequency and diversity of sand flies was the highest in areas of permanent preservation (APPs) (96.85%), and was lower in more urbanized areas. Lutzomyia dasypodogeton was the most frequent species in the APPs. Lutzomyia antunesi was the most frequent in neighborhoods with forest fragments and neighborhoods around APPs, and L. aragaoi was the most frequent in completely urbanized neighborhoods. A higher frequency and diversity of sand flies was observed in the rainy season (87.92%) than in the dry season (12.08%). Eight medically important species were captured, and Lutzomyia antunesi, which is associated with American cutaneous leishmaniasis and visceral leishmaniasis, was observed in all ecotypes throughout the year. CONCLUSIONS: We observed a high frequency and diversity of sand flies in all urban areas, and some species collected were major vectors of leishmaniasis. These results support the need for further studies of the natural rates of infection of these insects and the circulation of the disease in hosts and vectors.
Descritores: Psychodidae/classificação
Biodiversidade
Insetos Vetores/classificação
-Estações do Ano
População Urbana
Brasil
Leishmaniose Cutânea/transmissão
Leishmaniose Visceral
Leishmaniose Visceral/transmissão
Limites: Animais
Masculino
Feminino
Responsável: BR1.1 - BIREME


  5 / 890 LILACS  
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Alves, Leucio Câmara
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Id: biblio-829670
Autor: Agra, Maria Claudia Ribeiro; Costa, Pietra Lemos; Duque, Anderson Enio Silva; Soares, Efraim Naftali Lopes; Alves, Leucio Câmara; Ramos, Rafael Antonio Nascimento; Carvalho, Gílcia Aparecida de.
Título: Sandflies (diptera: psychodidae) in an urban area of Northeastern Brazil
Fonte: Rev. Soc. Bras. Med. Trop;49(6):698-702, Dec. 2016. tab, graf.
Idioma: en.
Resumo: Abstract INTRODUCTION: The sandfly fauna is well studied globally. In Brazil, sandfly fauna is very diverse in the Northeast region, especially in states such as Maranhão, Ceará, and Bahia. However, in the State of Pernambuco, the distribution of these insects is still not well known. Therefore, the objective of this study was to identify the different species that constitute the sandfly fauna in an urban area in the Northeast region of Brazil, where an outbreak of visceral leishmaniasis (VL) was recently reported. METHODS: The sandflies were collected from an urban area endemic for VL, at five collection points. The collection of samples was carried out from November 2014 to December 2015, using CDC light traps installed in intradomiciliary and peridomiciliary fashion. RESULTS: The collected sandflies (n = 297) belonged to eight species: Lutzomyia lenti, Lutzomyia longipalpis, Lutzomyia sallesi, Lutzomyia migonei, Lutzomyia walkeri, Lutzomyia capixaba, Lutzomyia carmelinoi, and Lutzomyia whitmani. Most of the specimens collected were peridomiciliary (247/297, 83%). L. lenti (154/297, 52%) was the most frequently sampled species, followed by L. longipalpis (88/297, 29.6%), and L. sallesi (42/297, 14.1%), which together accounted for over 90% of the collected sandfly specimens. CONCLUSIONS: The continued presence of L. longipalpis in urban areas, including that in intradomiciliary areas, with a predominance of females, is crucial because of the high possibility of them causing VL outbreaks, since this species is the main vector of Leishmania infantum in Brazil.
Descritores: Psychodidae/classificação
Insetos Vetores/classificação
-Psychodidae/virologia
Estações do Ano
População Urbana
Brasil
Densidade Demográfica
Insetos Vetores/virologia
Leishmaniose Visceral/transmissão
Limites: Animais
Masculino
Feminino
Responsável: BR1.1 - BIREME


  6 / 890 LILACS  
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Póvoa, Marinete Marins
Rangel, Elizabeth Ferreira
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Id: biblio-1041388
Autor: Santos, Thiago Vasconcelos dos; Galardo, Allan Kardec Ribeiro; Póvoa, Marinete Marins; Rangel, Elizabeth Ferreira.
Título: Increasing potential risk for American visceral leishmaniasis in Amapá, Brazil
Fonte: Rev. Soc. Bras. Med. Trop;49(6):772-773, Dec. 2016.
Idioma: en.
Resumo: Abstract: INTRODUCTION: The present note discusses some evidence on the increasing potential risk for American visceral leishmaniasis (AVL) transmission in the Northern Brazilian State of Amapá, the Guianan-Amazon biome. METHODS Early and present data about AVL were collected, including our recent entomological findings. RESULTS: The spread of the sand fly vector Lutzomyia longipalpis, and a sylvatic reservoir host, the crab-eating fox Cerdocyon thous in that region represents important findings related to the epidemiology of AVL in the Guianan-Amazon biome. CONCLUSIONS: These observations suggest that Brazilian authorities need to develop surveillance strategies in these risk areas.
Descritores: Psychodidae/parasitologia
Leishmania donovani/isolamento & purificação
Reservatórios de Doenças
Raposas/parasitologia
Insetos Vetores/parasitologia
Leishmaniose Visceral/transmissão
-Brasil/epidemiologia
Leishmaniose Visceral/epidemiologia
Limites: Humanos
Animais
Masculino
Responsável: BR1.1 - BIREME


  7 / 890 LILACS  
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Id: biblio-896987
Autor: Mendonça, Ivete Lopes de; Batista, Joilson Ferreira; Werneck, Guilherme Loureiro; Soares, Maria Regiane Araújo; Costa, Dorcas Lamounier; Costa, Carlos Henrique Nery.
Título: Serological tests fail to discriminate dogs with visceral leishmaniasis that transmit Leishmania infantum to the vector Lutzomyia longipalpis
Fonte: Rev. Soc. Bras. Med. Trop;50(4):483-488, July-Aug. 2017. tab.
Idioma: en.
Resumo: Abstract INTRODUCTION The control of reservoirs for Leishmania infantum -induced zoonotic visceral leishmaniasis requires the identification of dogs posing a population risk. Here, we assessed the performance of several assays to identify Lutzomyia longipalpis infectious dogs. METHODS We evaluated 99 dogs that were positive for visceral leishmaniasis based on parasite identification. Serological analyses were performed using an enzyme-linked immunosorbent assay, immunofluorescence antibody tests in 1:40 and 1:80 dilutions, rapid dual path platform tests, immunochromatographic assay with a recombinant rK39 antigen, fast agglutination screening tests, and direct agglutination tests. We also performed PCR to analyze peripheral blood and xenodiagnosis. RESULTS Forty-six dogs infected at least one L. longipalpis specimen. Although the serological test sensitivities were above 85% for detecting L. longipalpis infectious dogs, none showed a satisfactory performance, as both specificity (0.06 to 13%) and the area under the receiver operating characteristic curve (45 to 53%) were low. The PCR results were also weak, with a sensitivity of 30%, specificity of 72%, and an area under the receiver operating characteristic curve of 51%. The infected L. longipalpis proportion was higher among asymptomatic dogs than symptomatic dogs. Among the symptomatic dogs, those with ulceration-free skin diseases were more infectious, with an odds ratio of 9.3 (confidence interval of 1.10 - 428.5). The larger the number of insects fed, the greater the detected infectiousness. CONCLUSIONS Our study supports the imperative to develop novel technologies for identifying the infectious dogs that transmit L. infantum for the benefit of public health.
Descritores: Psychodidae/parasitologia
Testes Sorológicos/veterinária
Anticorpos Antiprotozoários/sangue
Leishmania infantum
Doenças do Cão/diagnóstico
Mosquitos Vetores/parasitologia
Leishmaniose Visceral/veterinária
-Testes Sorológicos/métodos
Sensibilidade e Especificidade
Doenças do Cão/parasitologia
Doenças do Cão/transmissão
Leishmaniose Visceral/diagnóstico
Leishmaniose Visceral/parasitologia
Leishmaniose Visceral/transmissão
Limites: Humanos
Animais
Masculino
Cães
Responsável: BR1.1 - BIREME


  8 / 890 LILACS  
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Id: biblio-990440
Autor: Costa, André Tetzl; Dias, Edelberto Santos; Souza, Andreza Geisiane Maia; Silva, Fabiana de Oliveira Lara e; Machado-Coelho, George Luiz Lins.
Título: Ecology of phlebotomine sand flies in an area of leishmaniasis occurrence in the Xakriabá Indigenous reserve, Minas Gerais, Brazil
Fonte: Rev. Soc. Bras. Med. Trop;52:e20180474, 2019. tab, graf.
Idioma: en.
Resumo: Abstract INTRODUCTION: Leishmaniasis is a complex vector-borne infectious diseases caused by protozoan parasites in the genus Leishmania and spread by hematophagous phlebotomine sand flies (Diptera: Psychodidae, Phlebotominae). The aim of this study was to investigate the phlebotomine fauna, endophily and exophily of the species found, and possible influence of climatic factors on their populations. METHODS: The study was conducted in the Xakriabá Indigenous Reserve (XIR) in the municipality of São João das Missões in northern Minas Gerais state, Brazil. Insects were collected over three consecutive nights in the last week of each month for 12 months from July 2015 to May 2016 from four houses in four different villages. Two traps were set up in each house: one in the intra-domicile and another in the peri-domicile. RESULTS: A total of 2,012 phlebotomine sand fly specimens representing 23 species and belonging to 10 different genera were captured and identified. Among the studied villages, Riacho do Brejo showed the highest density and diversity of phlebotomine sand flies. The species Lutzomyia longipalpis (80.3%) and Nyssomyia intermedia (7.3%), which are major vectors of visceral and cutaneous leishmaniasis, respectively, had the highest population densities, both in the intra- and peri-domicile. No correlation was observed between climatic factors and the density of phlebotomine sand flies. CONCLUSIONS: The results of the present study may contribute to a better understanding and targeting of the measures for preventing and controlling leishmaniasis by the authorities responsible for indigenous health.
Descritores: Psychodidae/fisiologia
Leishmaniose Cutânea/transmissão
Conservação dos Recursos Naturais
Insetos Vetores/fisiologia
Leishmaniose Visceral/transmissão
-Estações do Ano
Fatores de Tempo
Brasil
Análise de Variância
Densidade Demográfica
Distribuição por Sexo
Ecossistema
Distribuição Animal
Limites: Animais
Masculino
Feminino
Responsável: BR1.1 - BIREME


  9 / 890 LILACS  
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Id: biblio-1041572
Autor: Souza, Filipe Jonas Mattos Soares de; Silva, Vanderlei Campos; Coelho, Cláudia Alves de Andrade; Azevedo, Alfredo Carlos Rodrigues de; Bastos, Leonardo; Souza, Nataly Araujo de.
Título: Nocturnal activity rhythm of nyssomyia intermedia (diptera: psychodidae: phlebotominae) in campus fiocruz mata atlântica, an american cutaneous leishmaniasis transmission area, Rio de Janeiro, Brazil
Fonte: Rev. Soc. Bras. Med. Trop;52:e20180464, 2019. graf.
Idioma: en.
Projeto: Fundação Oswaldo Cruz.
Resumo: Abstract INTRODUCTION: Nyssomyia intermedia is an important vector of American cutaneous leishmaniasis. METHODS: Sand flies were captured in a Shannon trap and after landing on human collectors and retrieved monthly. Nocturnal activity was estimated using a log-linear model. RESULTS: Peak sand fly collection in the Shannon trap occurred in summer and winter, and peak fly collection on humans occurred in spring and summer. CONCLUSIONS: Ny. intermedia was captured in both the hottest and coldest months, indicating its adaptability to different seasons and the possibility of disease transmission at any time of the year in Campus Fiocruz Mata Atlântica, Brazil.
Descritores: Estações do Ano
Ciclos de Atividade/fisiologia
Leishmaniose Cutânea/transmissão
Insetos Vetores/fisiologia
-Psychodidae/classificação
Psychodidae/fisiologia
Brasil
Florestas
Limites: Animais
Responsável: BR1.1 - BIREME


  10 / 890 LILACS  
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Afonso, Margarete Martins dos Santos
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Id: lil-761164
Autor: Tanure, Aline; Peixoto, Jennifer Cunha; Afonso, Margarete Martins dos Santos; Duarte, Rosemere; Pinheiro, Aimara da Costa; Coelho, Suedali Villas Bôas; Barata, Ricardo Andrade.
Título: Identification of sandflies (Diptera: Psychodidae: Phlebotominae) blood meals in an endemic Leishmaniasis area in Brazil / Identificação do repasto sanguíneo de flebotomíneos (Diptera: Psychodidae: Phlebotominae) provenientes de área endêmica de Leishmaniose no Brasil
Fonte: Rev. Inst. Med. Trop. Säo Paulo;57(4):321-324, July-Aug. 2015. tab, ilus.
Idioma: en.
Projeto: Fundação de Amparo à Pesquisa do Estado de Minas Gerais.
Resumo: SUMMARYThe aim of this study was to identify blood meals of female sandflies captured in the municipality of Governador Valadares, an endemic area of visceral and cutaneous leishmaniasis, in the State of Minas Gerais, Brazil. From May 2011 to January 2012, captures were performed using HP light traps in four districts. There were 2,614 specimens (2,090 males and 524 females) captured; 97 engorged females were identified belonging to the species Lutzomyia longipalpis(82.1%) and Lutzomyia cortelezzii(17.9%). Considering simple and mixed feeding, the enzyme-linked immunosorbent assay revealed a predominance of chicken blood (43.6%) in Lutzomyia longipalpis, showing the important role that chickens exert around the residential areas of Governador Valadares. This finding increases the chances of sandflies contact with other vertebrates and consequently the risk of leishmaniasis transmission.

RESUMOO objetivo deste estudo foi identificar o repasto sanguíneo de fêmeas de flebotomíneos capturadas no município de Governador Valadares, área endêmica de leishmaniose visceral e tegumentar no Estado de Minas Gerais, Brasil. Entre maio de 2011 e janeiro 2012 foram realizadas capturas com armadilhas luminosas HP em quatro bairros. Foram capturados 2.614 exemplares (2.090 machos e 524 fêmeas). Noventa e sete fêmeas ingurgitadas foram identificadas como pertencentes às espécies Lutzomyia longipalpis(82,1%) e Lutzomyia cortelezzii(17,9%). Considerando a alimentação simples e a mista, o ensaio imunoenzimático revelou em Lutzomyia longipalpisuma predominância de sangue de galinhas (43,6%), mostrando o importante papel que galinhas podem exercer no peridomicílio, aumentando a chance de contato dos flebotomíneos com outros vertebrados e, consequentemente, o risco de transmissão da leishmaniose.
Descritores: Comportamento Alimentar/fisiologia
Insetos Vetores/fisiologia
Psychodidae/fisiologia
-Brasil
Galinhas
Doenças Endêmicas
Ensaio de Imunoadsorção Enzimática
Insetos Vetores/classificação
Leishmaniose Cutânea/transmissão
Leishmaniose Visceral/transmissão
Psychodidae/classificação
Roedores
Estações do Ano
Limites: Humanos
Animais
Masculino
Feminino
Cães
Tipo de Publ: Research Support, Non-U.S. Gov't
Responsável: BR1.1 - BIREME



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