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Texto completo SciELO Brasil
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Id: lil-623961
Autor: Li, Xiao-Yu.
Título: Immunomodulating Chinese herbal medicines
Fonte: Mem. Inst. Oswaldo Cruz;86(supl.2):159-164, 1991. graf, tab.
Idioma: en.
Conferência: Apresentado em: Brazilian-Sino Symposium on Chemistry and Pharmacology of Natural Products, Rio de Janeiro, Dec. 10-14, 1989.
Resumo: Traditional Chinese medicine always pays close attention to the strengthening of the patient"s general resitence against illness, ther are many Chinese herbs used for thousands of years are considered as tonics. Animal experiments and modern clinica; trails have shown that quite a number herbs are immunologically active, and most of the tonics are excellent immunomodulating agents, such as polysaccharides or saponins isolated from Astragalus mongholicus, Acanthopanax senticosus and Panax notoginseng, which stimulated mactophages, promoted antibody formation, actived complement and increased T lymphocyte proliferation. Moreover, some of them were proved to be anti-irradiative and protected animals from liver intoxications. On the other hand, some anti-inflammative or anti-pyretic hervs such as Tripterygium wilfordii, Aconitum and Artemiasiae species were proved to have immunosuppressive principles, some of them were now used clinically for the treatment of rheumatoid arthritis, chronic nephritis, systemic lupus erythematosis and various skin disorders. Pharmacological studies revealed that they have depressant effect on most of the humoral-immunity but not on the cell-mediated immunity. Some of them stimulated adrenal cortex functions and prolonged the survival time of transplanted allograft tissues.
Descritores: Tripterygium
Astragalus propinquus
Panax notoginseng
-Eleutherococcus
Aconitum
Responsável: BR1.1 - BIREME


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Id: lil-504112
Autor: Shohael, Abdullah Mohammad; Murthy, Hosakatte Niranjana; Hahn, Eun-Joo; Paek, Kee-Yoeup.
Título: Methyl jasmonate induced overproduction of eleutherosides in somatic embryos of Eleutherococcus senticosus cultured in bioreactors
Fonte: Electron. j. biotechnol;10(4):633-637, oct. 2007. tab.
Idioma: en.
Projeto: Ministry of Education and Human Resources Development; . Ministry of Commerce, Industry and Energy; . Ministry of Labor; . Korean Federation of Science and Technology Societies. Brain Pool Fellowship.
Resumo: This study was concentrated on the production of eleutherosides and chlorogenic acid in embryogenic suspension cultures of Eleutherococcus senticosus by exposing them to different concentrations (50-400 µM) of methyl jasmonate (MJ) during the culture period. In the bioreactor cultures, eleutheroside content increased significantly by elicitation of MJ, however, the fresh weight, dry weight and growth ratio of embryos was strongly inhibited by increasing MJ concentrations. The highest total eleutheroside (7.3 fold increment) and chlorogenic acid (3.9 fold increment) yield was obtained with 200 µM MJ treatment. There was 1.4, 3.4 and 14.9 fold increase in the eleutheroside B, E, and E1 production respectively with such elicitation treatment. These results suggest that MJ elicitation is beneficial for eleutheroside accumulation in the embryogenic cell suspension cultures.
Descritores: Eleutherococcus/metabolismo
Extratos Vegetais/análise
Reatores Biológicos
Reguladores de Crescimento de Planta/metabolismo
-Eleutherococcus/citologia
Eleutherococcus/embriologia
Membrana Celular/metabolismo
Técnicas de Cultura de Células
Responsável: CL1.1 - Biblioteca Central



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