Base de dados : LILACS
Pesquisa : B01.650.940.800.575.912.250.583.520.750 [Categoria DeCS]
Referências encontradas : 3 [refinar]
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Id: biblio-907505
Autor: Mamadalieva, Nilufar Z; Vinciguerra, Vittorio; Sobeh, Mansour; Ovidi, Elisa; Ashour, Mohamed L; Wink, Michael; Tiezzi, Antonio.
Título: GLC-MS profiling of non-polar extracts from Phlomis bucharica and P. salicifolia and their cytotoxicity / Perfiles GLC-MS de extractos no polares de Phlomis bucharica y P. salicifolia y su citotoxicidad
Fonte: Bol. latinoam. Caribe plantas med. aromát;14(6):442-448, Nov. 2015. tab.
Idioma: en.
Resumo: Phlomis species (Phlomis bucharica Regel and P. salicifolia Regel) have been traditionally used by Uzbek people as stimulant, tonic, diuretic, and in the treatment of ulcers, hemorrhoids, wounds and gynecological problems. In the present study, we characterized the chemical composition of non-polar extracts from P. bucharica and P. salicifolia by high resolution GLC-MS and evaluated their cytotoxicity. Concentrations of hexadecanoic acid in hexane and chloroform extracts were higher in P. bucharica than in P. salicifolia. 1,8- Cineol, camphor, borneol, alfa-terpinol, thymol, and isobornyl acetate were detected in P. bucharica but not in P. salicifolia. About 45 components were identified in P. bucharica and 40 in P. salicifolia. The chloroform extract from P. bucharica showed cytotoxicity in HeLa and HL-60 cells, with IC50 values of 26.07 and 29.42 ug/ml, respectively.

Las especies Phlomis (Phlomis bucharica Regel y P. salicifolia Regel) se han utilizado tradicionalmente por la gente de Uzbekistán como estimulante, tónico, diurético, y en el tratamiento de las úlceras, hemorroides, heridas y problemas ginecológicos. En el presente estudio, hemos caracterizado la composición química de los extractos no polares de P. bucharica y P. salicifolia por GLC-MS de alta resolución y se evaluó su citotoxicidad. Las concentraciones de ácido hexadecanoico en extractos de hexano y cloroformo fueron mayores en P. bucharica que en P. salicifolia. 1,8-cineol, alcanfor, borneol, se detectaron alfa-terpinol, timol, y acetato de isobornilo en P. bucharica pero no en P. salicifolia. Cerca de 45 componentes fueron identificados en P. bucharica y 40 en P. salicifolia. El extracto de cloroformo a partir de P. bucharica mostró citotoxicidad en células HL-60 y HeLa, con valores de CI 50 de 26,07 y 29,42 ug/ml, respectivamente.
Descritores: Óleos Voláteis/química
Óleos Voláteis/farmacologia
Phlomis/química
Extratos Vegetais/química
Extratos Vegetais/farmacologia
-Cromatografia Gasosa-Espectrometria de Massas/métodos
Ácido Palmítico/análise
Terpenos/análise
Responsável: CL1.1 - Biblioteca Central


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Id: lil-551363
Autor: Yüzbasioglu, Ertugrul; Dadandi, Mehmet Yasar; Õzcan, Servet.
Título: Estimation of phylogenetic relationships of Phlomis species based on seed protein polymorphism
Fonte: Electron. j. biotechnol;12(2):2-3, Apr. 2009. ilus, tab.
Idioma: en.
Resumo: In this study, phylogenetic relationships among 39 Phlomis taxa were investigated based on seed protein profiles produced by sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE). A total of 21 polypeptide bands were scored, of which, 19 were polymorphic among the taxa of the genus Phlomis. A distance matrix was generated from the similarity matrix which was computed by using Jaccard's similarity coefficients, based on polymorphic bands and then an UPGMA tree was established through cluster analysis performed on the distance matrix. Genetic distances ranged from 0.00 to 0.50 within subsection Dendrophlomis; from 0.00 to 0.625 within subsection Gymnophlomis and from 0.00 to 0.769 within subsection Oxyphlomis. The UPGMA tree formed four groups. The topology of the tree is in agreement with the taxonomic view regarding the section Phlomis as it is divided into three subsections as Dendrophlomis, Gymnophlomis and Oxyphlomis based on morphological characters. The grouping pattern of the tree also indicated that subsection Dendrophlomis is more closely related to subsection Gymnophlomis than subsection Oxyphlomis.
Descritores: Polimorfismo Genético
Phlomis/genética
Phlomis/química
Sementes/genética
-Eletroforese em Gel de Poliacrilamida
Proteínas de Plantas/genética
Dodecilsulfato de Sódio
Turquia
Responsável: CL1.1 - Biblioteca Central


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Id: lil-531922
Autor: Dadandi, Mehmet Yasar.
Título: Phylogenetic relationships among species of the subsection Dendrophlomis Bentham
Fonte: Electron. j. biotechnol;11(4):12-13, Oct. 2008. ilus, tab.
Idioma: en.
Projeto: Erciyes University.
Resumo: This study used randomly amplified polymorphic DNA markers to determine genetic relationships among species of the subsection Dendrophlomis. Twenty accessions of the eleven Phlomis taxa were evaluated to determine genetic variability using fourteen ten mer primers selected from a 125 random oligonucleotide set. These 14 selected primers generated 85 RAPD bands that ranged in size from 200 to 1200 base pairs. Of the total bands, 88 percent (75) were polymorphic among the samples. Genetic distances among accessions were computed to produce a dendrogram based on UPGMA. Genetic distances ranged from 0.133 (between P. amanica and P. monocephala) to 0.494 (between P. chimerae and P. lunariifolia). The UPGMA tree based on distances has two major groups. The first comprised 9 taxa that were clustered into two subgroups. The first subgroup consisted of P. viscosa, P. lycia, P. amanica and P. monocephala while the second comprised P. lunariifolia, P. bourgaei, P. longifolia var. longifolia, P. grandiflora var. grandiflora and P. grandiflora var. fimbrilligera. The second group comprised 2 species, P. leucophracta and P. chimerae. Species-specific bands were observed for P. lycia, P. leucophracta, P. lunariifolia, P. bourgaei, P. chimerae and P. longifolia var longifolia.
Descritores: Genoma de Planta
Phlomis/genética
Polimorfismo Genético/genética
-Marcadores Genéticos
Variação Genética
Filogenia
Técnica de Amplificação ao Acaso de DNA Polimórfico
Responsável: CL1.1 - Biblioteca Central



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