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Id: biblio-1283650
Autor: Passos, Bruno Goulart; Rangel, Leonardo da Silva; Albuquerque, Ricardo Diego Duarte Galhardo de; Caldas, Gabriel Rocha; Santos, Marcelo Guerra; Esteves, Ricardo dos Santos; Milton, Flora Aparecida; Neves, Francisco de Assis Rocha; Ruppelt, Bettina Monika; Santos, José Augusto Albuquerque dos; Faria, Robson Xavier; Rocha, Leandro.
Título: Ocotea pulchellaas an alternative against schistosomiasis: chemical analysis, development of nanoemulsion and biological control activity / Ocotea pulchellacomo una alternativa ante esquistosomiasis: análisis químico, desarrollo de una nanoemulsión y actividad en control biológico
Fonte: Bol. latinoam. Caribe plantas med. aromát;19(5):508-518, 2020. tab, ilus.
Idioma: en.
Resumo: The aim of this work was to evaluate the potential of the essential oil (EO) from Ocotea pulchella leaves as an alternative in the control of schistosomiasis. It was tested O. pulchella EO nanoformulation to assess its activity against adult Biomphalaria glabrata, their spawning and Schistossoma mansoni cercariae. Additionally, the EO chemical composition was investigated by gas-chromatography. Nanoemulsion were elaborated by the low energy method. The adult mollusks, their spawning and cercariae were placed in contact with nanoemulsion to calculate lethal concentrations. Myristicin, bicyclogermacrene and α-Pinene were the main substances in the EO. Nanoemulsion caused mortality of adult B. glabrata, its egg embryos and S. mansoni. These results suggest the use of this nanoemulsion as an alternative in the control of the schistosomiasis cycle.

El objetivo de este trabajo fue evaluar el potencial de los aceites esenciales (AE) de las hojas de Ocotea pulchellacomo una alternativa en el control de esquistosomiasis. Se probó una nanoformulación de AE de O. pulchellapara evaluar su actividad ante adultos de Biomphalaria glabrata, sus huevos y cercarías de Schistossoma mansoni. La nanoemulsión fue elaborada por el método de baja energía. Los moluscos adultos, sus huevos y cercarías se colocaron en contacto con la nanoemulsión para calcular concentraciones letales. Los compuestos mayoritarios en el AE fueron miristicina, biciclogermacreno y α-pineno. La nanoemulsión causó mortalidad en adultos de B. glabrata, sus huevos y a S. mansoni. Los resultados sugieren el uso de esta nanoemulsión como una alternativa en el control del ciclo de esquistosomiasis.
Descritores: Esquistossomose/prevenção & controle
Óleos Voláteis/administração & dosagem
Ocotea/química
Emulsões/administração & dosagem
Moluscos/efeitos dos fármacos
-Schistosoma mansoni/efeitos dos fármacos
Biomphalaria/efeitos dos fármacos
Óleos Voláteis/farmacologia
Óleos Voláteis/química
Controle Biológico de Vetores
Cromatografia Gasosa
Sesquiterpenos de Germacrano/análise
Dioxolanos/análise
Emulsões/farmacologia
Cercárias/efeitos dos fármacos
Interações Hidrofóbicas e Hidrofílicas
Derivados de Alilbenzenos/análise
Monoterpenos Bicíclicos/análise
Limites: Animais
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-1283651
Autor: Yamaguchi, Klenicy KL; Pedrosa, Tatiana do Nascimento; Vasconcellos, Marne Carvalho de; Lima, Emerson Silva; Veiga-Junior, Valdir F.
Título: Ocotea (Lauraceae) Amazonian essential oils chemical composition and their tyrosinase inhibition to use in cosmetics / Ocotea (Lauraceae) composición química de aceites esenciales amazónicos y su inhibición de la tirosinasa para usar en cosméticos
Fonte: Bol. latinoam. Caribe plantas med. aromát;19(5):519-526, 2020. tab.
Idioma: en.
Resumo: This study presents analyses on the chemistry, biology, pharmacology and chromatography of essential oils extracted from three species of the Ocotea genus: O. minor, O. ceanothifolia and O. leucoxylon. Leaves and stems, as well as the bark of O. minor, were processed using a modified Clevenger apparatus. Seven essential oils were obtained and analyzed using GC-FID and GC-MS, and their chemical compositions were determined. Assays of cytotoxicity, antioxidant and free radical scavenging activity, as well as tyrosinase and elastase inhibition were performed. In total, 25 constituents were identified, the principal being sesquiterpenes, such as spathulenol caryophyllene and its oxide. The oils did not present cytotoxicity using a hemolytic model, but also did not show antioxidant activity in the DPPH assay. Essential oil from stems of O. ceanothifolia, rich in spathulenol and caryophyllene oxide, demonstrated the capacity to inhibit 49.08% of tyrosinase activity at a concentration of 100 µg/mL. This research contributes to the chemical profile analysis of the three species of Ocoteathrough chemical investigations and biological activity, which are reported for the first time here in this study.

Este trabajo realiza un estudio químico, biológico, farmacológico y cromatográfico de aceites esenciales extraídos de tres especies del género Ocotea: O. minor, O. ceanothifoliay O. leucoxylon. Las hojas y tallos, así como la corteza de O. minor, se procesaron utilizando un aparato Clevenger modificado. Se obtuvieron siete aceites esenciales y se analizaron usando GC-FID y GC-MS, y se determinaron sus composiciones químicas. Se realizaron ensayos de citotoxicidad, actividad antioxidante y de atrapamiento de radicales libres, así como inhibición de tirosinasa y elastasa. En total, se identificaron 25 componentes, siendo los principales sesquiterpenos, como el spathulenol cariofileno y su óxido. Los aceites no presentaron citotoxicidad en un modelo hemolítico y tampoco mostraron actividad antioxidante en el ensayo con DPPH. El aceite esencial de tallos de O. ceanothifolia, rico en espatulenol y óxido de cariofileno, mostró capacidad para inhibir el 49.08% de la actividad de tirosinasa a una concentración de 100 µg/mL. Esta investigación contribuye al análisis del perfil químico de las tres especies de Ocotea a través de investigaciones químicas y actividad biológica la cual se informan por primera vez.
Descritores: Óleos Voláteis/farmacologia
Monofenol Mono-Oxigenase/antagonistas & inibidores
Ocotea/química
-Óxidos/análise
Sesquiterpenos/análise
Óleos Voláteis/química
Sequestradores de Radicais Livres
Lauraceae/química
Indústria Cosmética
Ionização de Chama
Cromatografia Gasosa-Espectrometria de Massas
Responsável: CL1.1 - Biblioteca Central


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Texto completo SciELO Brasil
Texto completo
Id: biblio-1132155
Autor: Brustulim, Libardone José Ribeiro; Monteiro, Luciane Mendes; Almeida, Valter Paes de; Raman, Vijayasankar; Maia, Beatriz Helena Lameiro de Noronha Sales; Casapula, Inaiara; Paludo, Kátia Sabrina; Bussade, Julia Emília; Rehman, Junaid Ur; Kahn, Ikhlas Ahmed; Farago, Paulo Vitor; Budel, Jane Manfron.
Título: Ocotea porosa: Anatomy and Histochemistry of Leaves and Stems, Chemical Composition, Cytotoxicity and Insecticidal Activities of Essential Oil
Fonte: Braz. arch. biol. technol;63:e20190082, 2020. tab, graf.
Idioma: en.
Projeto: USDA-Discovery & Development of Natural Products.
Resumo: Abstract Ocotea porosa (Nees & Mart.) Barroso, commonly known as "imbuia", "canela-imbuia" or "imbuia-amarela" in Brazil, is a tree of the Southern Atlantic Forest. The present study investigates the anatomy of leaf and stem, volatile oil chemistry, as well as cytotoxicity and insecticidal activities of the essential oil of O. porosa. Species identification was achieved by anatomy features, mainly due to paracytic and anomocytic stomata; non-glandular trichomes; biconvex midrib and petiole with a collateral open arc vascular bundle; presence of a sclerenchymatous layer, starch grains and crystal sand in the stem; and the presence of phenolic compounds in the epidermis, phloem and xylem of the midrib, petiole and stem. The main volatile components of the essential oil were α-pinene (19.71%), β-pinene (13.86%) and bicyclogermacrene (24.62%). Cytotoxicity against human cancer cell (MCF-7), mouse cancer cell (B16F10) and mouse non-tumoral cell (McCoy) was observed as well as insecticidal activity of the essential oil against susceptible 'Ft. Dix' bed bugs (Cimex lectularius L.) by topical application.
Descritores: Percevejos-de-Cama
Óleos Voláteis/farmacologia
Ocotea/anatomia & histologia
Ocotea/química
Inseticidas/farmacologia
-Testes de Toxicidade
Caules de Planta/química
Folhas de Planta/química
Histocitoquímica
Responsável: BR1.1 - BIREME


  4 / 20 LILACS  
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Texto completo SciELO Brasil
Texto completo
Id: biblio-1155533
Autor: Betim, Fernando Cesar Martins; Oliveira, Camila Freitas de; Montrucchio, Deise Prehs; Miguel, Obdulio Gomes; Miguel, Marilis Dallarmi; Maurer, Juliana Bello Baron; Dias, Josiane de Fátima Gaspari.
Título: Preliminary evaluation of the larvicidal activity of extracts and fractions from Ocotea nutans (Nees) Mez against Aedes aegypti
Fonte: Rev. Soc. Bras. Med. Trop;54:e0576-2020, 2021. tab.
Idioma: en.
Projeto: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
Resumo: Abstract INTRODUCTION: Aedes aegypti is the main vector of dengue and yellow fever. Recently, the use of plant-sourced larvicides has gained momentum. METHODS: The hydroethanolic extracts and fractions ofOcotea nutansleaves and stems were bioassayed to determine the larvicidal efficacy of these samples. RESULTS: S-HEX (hexane fraction from the crude stem extract) demonstrated high potential for controlling third-stage larvae, with an LC50 of 14.14 µg.mL-1 (concentration required to inhibit 50% of the treated larvae). CONCLUSIONS Extracts from O. nutans were effective against third-stage larvae ofA. aegyptiafter 24 h of exposure.
Descritores: Aedes
Mosquitos Vetores
Inseticidas/farmacologia
-Extratos Vegetais/farmacologia
Folhas de Planta
Ocotea
Larva
Limites: Animais
Responsável: BR1.1 - BIREME


  5 / 20 LILACS  
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Id: biblio-1102241
Autor: Moussavou, Ulrich Privat Akendengué; Mattos, Camila; Vinturelle, Rafaelle; Tietbohl, Luis Armando Candido; Albuquerque, Ricardo Diego Duarte Galhardo de; Ruppelt, Bettina Monika; Guerra Santos, Marcelo; Faria, Robson Xavier; Carvalho Queiroz, Margareth Maria de; Ratcliffe, Norman; Folly, Evelize; Rocha, Leandro.
Título: Chemical composition and acaricidal activity of Ocotea notata (Lauraceae), an endemic species from Brazil, against the cattle tick Rhipicephalus microplus / Composición química y actividad acaricida de Ocotea notata (Lauraceae), una especie endémica de Brasil, contra la garrapata del ganado Rhipicephalus microplus
Fonte: Bol. latinoam. Caribe plantas med. aromát;18(6):555-565, nov. 2019. tab, ilus.
Idioma: en.
Resumo: Rhipicephalus microplus, is one parasites that cause severe productivity losses in the cattle industry of Brazil and shows increasing resistance to conventional pesticides. This research aims to study the chemical composition, and acaricidal activity of the essential oil from Ocotea notata leaves, a brazilian endemic species, against R. microplus. The effect on R. microplus engorged adult females was evaluated using the immersion test. The oil reduced the survival by 90% after incubation for 15 days and there was 100% reduction for posture inhibition and reproductive capacity. These results suggest that the O. notata essential oil has activity on the R. microplus.

Rhipicephalus microplus, es un parásito que causa graves pérdidas de productividad en la industria ganadera de Brasil y muestra una creciente resistencia a los pesticidas convencionales. Esta investigación tiene como objetivo estudiar la composición química y la actividad acaricida del aceite esencial de las hojas de Ocotea notata, una especie endémica brasileña, contra R. microplus. El efecto sobre las hembras adultas engordadas de R. microplus se evaluó mediante la prueba de inmersión. El aceite redujo la supervivencia en 90% después de la incubación durante 15 días y hubo una reducción del 100% para la inhibición de la postura y la capacidad reproductiva. Estos resultados sugieren que el aceite esencial de O. notata tiene actividad contra R. microplus.
Descritores: Óleos Voláteis/farmacologia
Ocotea/química
Rhipicephalus/efeitos dos fármacos
Acaricidas/farmacologia
-Terpenos/análise
Carrapatos/efeitos dos fármacos
Brasil
Óleos Voláteis/química
Controle de Ácaros e Carrapatos/métodos
Folhas de Planta/química
Lauraceae/química
Acaricidas/química
Cromatografia Gasosa-Espectrometria de Massas
Limites: Animais
Responsável: CL1.1 - Biblioteca Central


  6 / 20 LILACS  
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Id: biblio-1145991
Autor: Gribner, Caroline; Moura, Paula Francislaine; Veiga, Andressa; Gatto, Larissa Junqueira; Santos, Nayana Cristina da Silva; Marques, Francisco de Assis; Zattoni, Ingrid; Valdameri, Glaucio; Dias, Josiane de Fatima Gaspari; Miguel, Obdulio Gomes; Zanin, Sandra Maria Warumby.
Título: Componentes químicos del aceite esencial de Ocotea paranaensis (Lauraceae) y sus propiedades antioxidantes, anticancer y antimicrobianas / Chemical constituents of Ocotea paranaensis (Lauraceae) essential oil and their antioxidant, anticancer and antimicrobial properties
Fonte: Bol. latinoam. Caribe plantas med. aromát;19(5):495-507, 2020. tab, graf.
Idioma: en.
Resumo: La composición química del aceite esencial obtenido de las ramas de Ocotea paranaensis se estudió por cromatografía de gases/espectrometría de masas (CG/MS). Se identificaron veintisiete compuestos, que comprenden el 94,82% de los componentes totales. El aceite se caracterizó por una concentración relativamente alta de sesquiterpenos (62,96%), sesquiterpenos oxigenados (33,33%) y diterpeno (3,70%). En cuanto a los compuestos principales, se destacaron Z-nerolidol (19,16%), germacreno D (12,92%) y α-bulnesene (8,47%), que correspondieron al 40,55% de las sustancias encontradas. El aceite esencial analizado de Ocotea paranaensis tiene una buena acción reductora de fosfomolibdeno y es moderadamente tóxico para la Artemia salina (LC50 = 147,91 µg/mL). Mostró potencial hemolítico y actividad moderada contra Staphylococcus aureus (concentración inhibitoria mínima MIC = 250 µg/mL) y Pseudomonas aeruginosa (MIC = 500 µg/mL). No se observaron resultados satisfactorios de citotoxicidad en el linaje H460 y HeLa.

The chemical composition of the essential oil obtained from the branches of Ocotea paranaensis was studied by gas chromatography/mass spectrometry (GC/MS). Twenty-seven compounds, comprising 94.82% of the total components, were identified. The oil showed relatively high concentration of sesquiterpenes (62.96%), oxygenated sesquiterpenes (33.33%), and diterpene (3.70%). Regarding the major compounds, Z-nerolidol (19.16%), germacrene D (12.92%) and α-bulnesene (8.47%) could be highlighted, which corresponded to 40.55% of the substances that were found. The essential oil from Ocotea paranaensis has phosphomolybdenum reducing action and is moderately toxic to the Artemia salina (LC50 = 147.91 µg/mL). It showed haemolytic potential and moderate activity against Staphylococcus aureus, (minimum inhibitory concentration MIC = 250 µg/mL) and Pseudomonas aeruginosa (MIC = 500 µg/mL). No satisfactory cytotoxicity results were observed in lineage H460 and HeLa.
Descritores: Ocotea/química
Anti-Infecciosos
Antineoplásicos
Antioxidantes
-Extratos Vegetais
Cromatografia
Medicina Tradicional
Tipo de Publ: Estudo de Avaliação
Responsável: BR1.1 - BIREME


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Texto completo SciELO Cuba
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Id: biblio-845103
Autor: Delgado Avila, Wilman Antonio; CucaSuárez, Luis Enrique; Caroprese, José Fernando.
Título: Composición química del aceite esencial de Ocotea cymbarum Kunth (cascarillo y/o sasafrás) de la región Orinoquia / Chemical composition of essential oil of Ocotea cymbarum Kunth (cascarilla and/or sassafras) from the Orinoquía region
Fonte: Rev. cuba. plantas med;21(3), jul.-set. 2016. ilus, tab.
Idioma: es.
Resumo: Introducción: en algunas poblaciones de la Orinoquia colombiana y/o venezolana venden, en plazas de mercado, los aceites de cascarillo y sasafrás; estos aceites son empleados para aliviar dolencias como artritis reumática, afecciones respiratorias y tratar picaduras de insectos y animales ponsoñosos. Los productos se obtienen de la especie Ocotea cymbarum Kunth, la cual tiene una abundante sinonimia botánica como Alseodaphne cymbarum,Licaria cymbarum, Misanteca cymbarum, Nectandra barcellensis, Nectandra cymbarum, Nectandra elaiophora, Nectandra oleífera y Ocotea barcellensis. Objetivo: realizar un análisis comparativo de las características fisicoquímicas del aceite esencial de cascarillo y/o sasafrás (posible Ocotea cymbarum Kunth). Métodos: la composición química relativa de los aceites obtenidos de madera y corteza fue determinada mediante cromatografía de gases acoplada a espectrometría de masas (CG-EM), el cálculo y comparación de índices de retención en columnas de polaridad ortogonal y la comparación de los espectros de masas por impacto electrónico con los de las bases de datos NIST08.L, Wiley9.L. Resultados: fueron determinados 45 compuestos en las muestras analizadas y más del 90 por ciento de la composición relativa establecida para cada aceite corresponde a compuestos monoterpénicos principalmente alcanfor y alfa-terpineol. Al realizar un análisis de las rutas biosintéticas que conducen a la generación de los principales compuestos detectados en los aceites analizados, se evidenció que las especies de donde se obtuvieron estos aceites, presentan diferentes grados de evolución micromolecular. Conclusión: los aceites de cascarillo y sasafrás provienen de especies vegetales con diferentes grados de evolución química. Este resultado refuerza la evidencia de la alta diversidad biológica de la familia Lauraceae. El trabajo fue realizado con el apoyo financiero del Laboratorio de Productos Naturales Vegetales del departamento de Química de la Universidad Nacional de Colombia sede Bogotá(AU)

Introduction: cascarilla and sassafras oils are sold in market places of some settlements in the Colombian and/or Venezuelan Orinoquía. These oils are used to alleviate conditions such as rheumatoid arthritis and respiratory disorders, and to treat the bites of insects and poisonous animals. The oils are obtained from the species Ocotea cymbarum Kunth, which displays abundant botanical synonymy as Alseodaphne cymbarum, Licaria cymbarum,Misanteca cymbarum, Nectandra barcellensis, Nectandra cymbarum, Nectandra elaiophora, Nectandra oleífera and Ocotea barcellensis. Objective: carry out a comparative analysis of the physicochemical characteristics of essential oil of cascarilla and/or sassafras (Ocotea cymbarum Kunth).Methods: the relative chemical composition of oils obtained from wood and bark was determined by gas chromatography coupled with mass spectrometry (GC-MS). Estimation and comparison of retention indices was conducted with orthogonal polarity columns. Comparison of electron impact mass spectra was performed with the databases NIST08.L and Wiley9.L. Results: forty-five compounds were determined from the samples analyzed. More than 90 percent of the relative composition established for each oil corresponds to monoterpenic compounds, mainly camphor and alpha-terpineol. Analysis of the biosynthetic pathways leading to the generation of the main compounds detected in the oils studied, showed that the species from which the oils were obtained exhibit varying degrees of micromolecular evolution. Conclusion: cascarilla and sassafras oils are obtained from plant species at varying stages of chemical evolution. This result constitutes additional evidence of the great biological diversity of the Lauraceae family. The study was conducted with financial support from the Natural Plant Products Laboratory of the Chemistry Department at the National University of Colombia at Bogotá(AU)
Descritores: Artrite/tratamento farmacológico
Doenças Respiratórias/tratamento farmacológico
Óleos Voláteis/uso terapêutico
Cromatografia Gasosa/métodos
Mordeduras e Picadas de Insetos/tratamento farmacológico
Animais Venenosos/lesões
-Colômbia
Ocotea/química
Limites: Humanos
Masculino
Feminino
Responsável: CU1.1 - Biblioteca Médica Nacional


  8 / 20 LILACS  
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Texto completo SciELO Brasil
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Id: biblio-886737
Autor: MORAES, MARCILIO M DE; CAMARA, CLAUDIO A G DA; SILVA, MILENA M C DA.
Título: Comparative toxicity of essential oil and blends of selected terpenes of Ocotea species from Pernambuco, Brazil, against Tetranychus urticae Koch
Fonte: An. acad. bras. ciênc;89(3):1417-1429, July-Sept. 2017. tab, graf.
Idioma: en.
Projeto: Conselho Nacional de Desenvolvimento Científico e Tecnológico; . Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES).
Resumo: ABSTRACT Essential oils from the leaves of two species of the genus Ocotea that occur in the Atlantic Forest in the state of Pernambuco, Brazil, were analyzed using gas chromatography-mass spectrometry. The acaricidal activity of these oils as well as 11 selected components and blends were evaluated in fumigation and residual contact tests against the two-spotted spider mite (Tetranychus urticae). Sixty-seven constituents were identified, totaling 97.3 ± 0.3% and 97.8 ± 0.5% of the oils from O. duckei and O. glomerata, respectively. Sesquiterpene was the dominant class. The compounds β-caryophyllene (18.6 ± 0.1%) and aromadendrene (17.3 ± 0.6%) were the main constituents of the oils from O. duckei and O. glomerata, respectively. Acaricidal action varied depending on the method employed, species and chemical nature of the selected constituents. The mites were susceptible to the oils and chemical constituents using the fumigation method. The O. duckei oil was respectively 2.5-fold and 1.5-fold more toxic than the O. glomerata oil using the fumigation and residual contact methods. Among the selected constituents, β-caryophyllene was the most toxic, independently of the method employed. The individual toxicity of the selected compounds and their blends as well as the role of these constituents in the overall toxicity of the essential oils are also discussed.
Descritores: Terpenos/toxicidade
Óleos Voláteis/toxicidade
Ocotea/química
Tetranychidae/efeitos dos fármacos
Acaricidas/toxicidade
-Terpenos/isolamento & purificação
Brasil
Acaricidas/isolamento & purificação
Cromatografia Gasosa-Espectrometria de Massas
Limites: Animais
Tipo de Publ: Estudo Comparativo
Responsável: BR1.1 - BIREME


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Id: biblio-914948
Autor: Moraes, Marcilio M de; Camara, Claudio AG da; Araujo, Carolina A de.
Título: Chemical composition of essential oil from leaves of Ocotea limae Vattimo Gil. and Ocotea gardneri (Meisn. ) Mez. growing wild in Atlantic forest of North-Eastern Brazil / [Composición química del aceite esencial de las hojas de Ocotea limae Vattimo Gil. y Ocotea gardneri (Meisn. ) Mez. nativas de la floresta Atlántica del Nordeste de Brasil
Fonte: Bol. latinoam. Caribe plantas med. aromát;16(6):586-593, nov. 2017. tab.
Idioma: en.
Projeto: Fundação de Amparo à Ciencia e Tecnologia do Estado de Pernambuco; . Conselho Nacional de Desenvolvimento Científico e Tecnológico.
Resumo: Essential oils from leaves of Ocotea limae and Ocotea gardneri species were analyzed by GC-FID and GC-MS. The analysis revealed the presence of 48 components accounting for 98.1 ± 1.3% e 98.0 ± 0.5% of the essential oils from the O. limae and O. gardneri, respectively. The oils were characterized by high percentage of sesquiterpenes. The mains compounds identified in the essential oils were spathulenol (13.3 ± 0.5%), ß-caryophyllene (12.4 ± 0.5%), bicyclogermacrene (11.3 ± 0.4%) and germacrene D (10.9 ± 0.3%) from the O. limae and germacrene D (26.9 ± 0.9%) e bicyclogermacrene (21.7 ± 0.7%) from the O. glomerata.

Los aceites esenciales de hojas de Ocotea limae y Ocotea gardneri fueron analizados por GC-FID y GC-MS. El análisis reveló la presencia de 48 componentes que representan 98,1 ± 1,3% y 98,0 ± 0,5% de los aceites esenciales de O. limae y O. gardneri, respectivamente. Los aceites se caracterizaron por un alto porcentaje de sesquiterpenos. Los principales compuestos identificados en los aceites esenciales fueron espatulenol (13,3 ± 0,5%), ß-cariofileno (12,4 ± 0,5%), biciclogermacreno (11,3 ± 0,4%) y germacreno D (10,9 ± 0,3%) de O. limae y germacreno D (26,9 ± 0,9%) y bicyclogermacreno (21,7 ± 0,7%) de la O. glomerata.
Descritores: Sesquiterpenos/análise
Óleos Voláteis/química
Folhas de Planta/química
Ocotea
-Terpenos/análise
Brasil
Cromatografia Gasosa/métodos
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-889413
Autor: Damasceno, Carolina Sette Barbosa; Oliveira, Letícia Freire de; Szabo, Ellis Marina; Souza, Ângela Maria; Dias, Josiane Fatima Gaspari; Miguel, Marilis Dalarmi; Miguel, Obdúlio Gomes.
Título: Chemical composition, antioxidant and biological activity of Ocotea bicolor Vattimo-Gil (LAURACEAE) essential oil
Fonte: Braz. J. Pharm. Sci. (Online);53(4):e17298, 2017. tab, graf.
Idioma: en.
Resumo: ABSTRACT The essential oil composition of the Ocotea bicolor, native plant of Brazil, was studied for the first time. The essential oil of the leaf was obtained by hydrodistillation and analyzed by GC/MS. The analytical procedure revealed a predominance of sesquiterpenes, δ-cadinene (7.39%), ß-sesquiphellandrene (6.67%), ß-elemene (5.41%) and α-cadinol (5,23%). The essential oil was submitted to brine shrimp toxicity evaluation, antioxidant and antibacterial tests. The antioxidant activity by the formation of phosphomolybdenum complex method presented positive results. The minimum inhibitory concentration (MIC) values were higher than 1000 µg/mL for the microorganisms tested. Toxicity activity revealed LC50 results of 40.10 (µg/mL), being toxic to the organisms in this study
Descritores: Óleos Voláteis/análise
Lauraceae/classificação
Lauraceae/química
Antioxidantes/análise
-Plantas Medicinais/anatomia & histologia
Ocotea/efeitos adversos
Tipo de Publ: Técnicas In Vitro
Responsável: BR40.1 - DBD - Divisão de Biblioteca e Documentacão do Conjunto das Químicas



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