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Id: biblio-842035
Autor: Song, Xu; Cao, Mei; Yin, Zhongqiong; Jia, Renyong; Zou, Yuanfeng; Li, Lixia; Yue, Guizhou; Liang, Xiaoxia; Yin, Lizi; He, Changliang.
Título: Effects of polysaccharide from Ophiopogon japonicus on immune response to Newcastle disease vaccine in chicken
Fonte: Pesqui. vet. bras = Braz. j. vet. res;36(12):1155-1159, Dec. 2016. tab.
Idioma: en.
Projeto: Sichuan Agricultural University; . International cooperation projects of Sichuan Province; . Sichuan Youth Science; . Technology Innovation Research Team; . National Natural Science Foundation of China.
Resumo: In order to investigate the immune enhancement effects of Ophiopogon japonicus polysaccharide Ophiopogon japonicus (OJPS) on Newcastle disease (ND) live vaccine, chickens vaccinated against ND live vaccine was orally administered with the OJPS at high, medium and low concentrations respectively. In negative control group, chickens were given orally equal volume of physiological saline. On day 14, 21 and 28, the serum antibody titer, erythrocyte-C3b receptor rosette rate (E-C3bRR), erythrocyte-C3b immune complex rosette rate (E-ICRR) and peripheral lymphocyte proliferation were measured. The results showed that at most time points, the antibody titer, peripheral lymphocyte proliferation, E-C3bRR and elimination rate of immune complex of three OJPS administrating groups were significantly higher (P<0.05) than those in negative control group. It indicated that OJPS could significantly improve the immune efficacy of Newcastle disease live vaccine, Ophiopogon japonicus polysaccharide possessed synergistical immunoenhancement.(AU)
Descritores: Galinhas/virologia
Doença de Newcastle/imunologia
Ophiopogon/química
Vacinas Virais/análise
-Adjuvantes Imunológicos
Anticorpos/sangue
Eritrócitos/imunologia
Linfócitos/imunologia
Limites: Animais
Responsável: BR1.1 - BIREME



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