× Atenção: Esta versão do sistema de pesquisa será desativada em 01/12/2022. Recomendamos a utilização da nova versão disponível em pesquisa.bvsalud.org


Base de dados : LILACS
Pesquisa : B04.280.030 [Categoria DeCS]
Referências encontradas : 53 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 6 ir para página                

  1 / 53 LILACS  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo SciELO Brasil
Carvalho, Werther Brunow de
Texto completo
Texto completo
Id: biblio-1092153
Autor: Oliveira, Felipe Rezende Caino de; Macias, Krisna de Medeiros; Rolli, Patricia Andrea; Colleti Junior, José; Carvalho, Werther Brunow de.
Título: Management of acute respiratory distress syndrome in a child with adenovirus pneumonia: case report and literature review / Manejo da síndrome do desconforto respiratório agudo em criança com pneumonia por adenovírus: relato de caso e revisão da literatura
Fonte: Rev. Paul. Pediatr. (Ed. Port., Online);38:e2018280, 2020. graf.
Idioma: en.
Resumo: ABSTRACT Objective: To report the case of a child who developed acute respiratory distress syndrome (ARDS) from a pulmonary infection by adenovirus. Case description: A female patient aged 2 years and 6 months, weighting 10,295 grams developed fever, productive cough and vomiting, later on progressing to ARDS despite initial therapy in accordance with the institutional protocol for ARDS treatment. The child evolved to refractory hypoxemia and hypercapnia, requiring high parameters of mechanical pulmonary ventilation and use of vasoactive agents. In the treatment escalation, the patient received steroids, inhaled nitric oxide (iNO), was submitted to the prone position, started oscillatory high-frequency ventilation (HFOV) and extracorporeal membrane oxygenation (ECMO) was indicated due to severe refractory hypoxemia. During this time, the patient's clinical response was favorable to HFOV, improving oxygenation index and hypercapnia, allowing the reduction of vasoactive medications and mechanical ventilation parameters, and then the indication of ECMO was suspended. The patient was discharged after 26 days of hospital stay without respiratory or neurological sequelae. Comments: Adenovirus infections occur mainly in infants and children under 5 years of age and represent 2 to 5% of respiratory diseases among pediatric patients. Although most children with adenovirus develop a mild upper respiratory tract disease, more severe cases can occur. ARDS is a serious pulmonary inflammatory process with alveolar damage and hypoxemic respiratory failure; Adenovirus pneumonia in children may manifest as severe pulmonary morbidity and respiratory failure that may require prolonged mechanical ventilation. Exclusive pulmonary recruitment and HFOV are advantageous therapeutic options.

RESUMO Objetivo: Descrever paciente que evoluiu com síndrome do desconforto respiratório agudo (SDRA) a partir de infecção pulmonar por adenovírus. Descrição do caso: Paciente de dois anos e seis meses, sexo feminino, peso de 10295 g, que apresentou com quadro de febre, tosse produtiva e vômitos, evoluindo para SDRA. Apesar da terapêutica inicial em conformidade com o protocolo institucional de tratamento da SDRA, a criança evoluiu para hipoxemia e hipercapnia refratárias, necessitando de elevados parâmetros de ventilação pulmonar mecânica e utilização de agentes vasoativos. No escalonamento da terapêutica, a paciente recebeu terapias adjuvantes, foi iniciada ventilação oscilatória de alta frequência (VOAF) e indicada oxigenação por membrana extracorpórea (OMEC) pela hipoxemia grave refratária. Nesse ínterim, a paciente apresentou resposta clínica favorável à VOAF, melhorando do quadro ventilatório e possibilitando a redução das medicações vasoativas e dos parâmetros de ventilação mecânica. A paciente recebeu alta hospitalar após 26 dias de internação, sem sequelas respiratórias ou neurológicas. Comentários: As infecções por adenovírus ocorrem principalmente em lactentes e crianças com menos de cinco anos de idade e representam de 2 a 5% das doenças respiratórias entre os pacientes pediátricos. Embora a maioria das crianças com infecção por adenovírus desenvolva doença leve do trato respiratório superior, casos mais graves podem ocorrer com comprometimento do trato respiratório inferior. A pneumonia por adenovírus em crianças pode se manifestar com morbidade pulmonar grave e insuficiência respiratória com risco de vida, o que resulta na necessidade de suporte mecânico prolongado. O recrutamento pulmonar exclusivo pela VOAF pode ser uma opção terapêutica útil.
Descritores: Pneumonia Viral/complicações
Síndrome do Desconforto Respiratório do Recém-Nascido/etiologia
Síndrome do Desconforto Respiratório do Recém-Nascido/terapia
Ventilação de Alta Frequência/métodos
Oxigenação por Membrana Extracorpórea/métodos
Infecções por Adenovirus Humanos/complicações
-Pneumonia Viral/diagnóstico por imagem
Metilprednisolona/uso terapêutico
Ecocardiografia
Adenoviridae/isolamento & purificação
Decúbito Ventral
Intubação Intratraqueal
Anti-Inflamatórios/uso terapêutico
Limites: Humanos
Feminino
Pré-Escolar
Tipo de Publ: Relatos de Casos
Revisão
Responsável: BR1.1 - BIREME


  2 / 53 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Chile
Texto completo
Id: lil-706522
Autor: Zhao, Yongliang; Dong, Zongming; Li, Tengfei; Huang, Gang.
Título: A simple negative selection method to identify adenovirus recombinants using colony PCR
Fonte: Electron. j. biotechnol;17(1):8-8, Jan. 2014. ilus, tab.
Idioma: en.
Resumo: Background: The AdEasy system is a fast-track system for generating recombinant adenoviruses using the efficient homologous recombination machinery between shuttle and adenovirus backbone plasmids in Escherichia coli BJ5183 cells. The key step is homologous recombination in BJ5183 cells, which is driven by RecA activity. However, culture time is stringently limited to reduce the damage to recombinant plasmids by RecA activity. Therefore, rapid identification of recombinant adenoviruses within the limited time-period is critical. Results: We developed a simple negative selection method to identify recombinant adenoviruses using colony PCR, which improves the efficiency of adenovirus recombination screening and packaging. Conclusions: The negative selection method to identify AdEasy adenovirus recombinants by colony PCR can identify the recombined colony within a short time-period, and maximally avoid damage to the recombinant plasmid by limiting recombination time, resulting in improved adenovirus packaging.
Descritores: Seleção Genética/genética
Adenoviridae/isolamento & purificação
Adenoviridae/genética
Reação em Cadeia da Polimerase/métodos
-Clonagem Molecular
Recombinação Homóloga
Responsável: CL1.1 - Biblioteca Central


  3 / 53 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Texto completo
Id: biblio-1287045
Autor: Cancelier, Ana Carolina Lobor; Dhurandhar, Nikhil V; Peddibhotla, Swetha; Atkinson, Richard L; Silva, Helena C G; Trevisol, Daisson J; Schuelter-Trevisol, Fabiana.
Título: Adenovirus 36 infection and daycare starting age are associated with adiposity in children and adolescents
Fonte: J. pediatr. (Rio J.);97(4):420-425, July-Aug. 2021. tab.
Idioma: en.
Resumo: Abstract Objective This study aimed to investigate human adenovirus 36 (Adv36) as an associated factor for adiposity in children and adolescents aged 9-12 years. Methods This was a case-control study comparing overweight (cases) and eutrophic (controls) children and adolescents aged 9-12 years based on their body mass index in relation to human adenovirus 36 serology. Human adenovirus 36-specific neutralizing antibodies were assessed using the serum neutralization assay, and a questionnaire regarding the subjects' personal backgrounds, breastfeed history, age of starting daycare, and eating and exercise habits was also applied. Results A total of 101 (51, eutrophic; 50, overweight) children were included in the study. The Adv36 seropositivity rate was of 15.8%, which increased the chance of being overweight by 3.17 times (p = 0.049). Enrollment in a full-time daycare center before the age of 24 months increased the chance of being overweight by 2.78 times (p = 0.027). Metabolic parameters (total cholesterol and blood glucose) were insignificantly different among children who were seropositive or seronegative for human adenovirus 36. Conclusion This study concluded that excessive weight was positively associated with seropositivity for human adenovirus 36. Early enrollment in a full-time daycare was also an associated factor for obesity. Such data, confirmed in new studies, reinforces the role of human adenovirus 36 in the increase of childhood adiposity.
Descritores: Adenovírus Humanos
Obesidade Pediátrica
-Índice de Massa Corporal
Estudos de Casos e Controles
Adenoviridae
Adiposidade
Limites: Humanos
Pré-Escolar
Criança
Adolescente
Responsável: BR1.1 - BIREME


  4 / 53 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Chile
Texto completo
Id: lil-597504
Autor: Catroxo, M. H. B; Martins, A. M. C. R. P. F; Petrella, S; Curi, N. A; Melo, N. A.
Título: Research of Viral Agent in Free-living Pigeon Feces (Columba livia) in the City of São Paulo, SP, Brazil, for Transmission Electron Microscopy / Investigación de Agentes Virales en Heces de Palomas de Vida Libre (Columba livia) en la Ciudad de São Paulo, SP, Brasil, Através de Miscroscopía Electrónica de Transmisión
Fonte: Int. j. morphol;29(2):628-635, June 2011. ilus.
Idioma: en.
Resumo: The pigeon feces are vehicle of diseases both for humans and other animal species. In these birds, the most important viral diseases of the digestive tract are transmitted by the paramyxovirus, adenovirus and coronavirus. Avian paramyxoviruses have been isolated from a variety of species of free living and domestic birds worldwide, with several symptoms and clinical signs and economic losses. Paramyxoviruses belong to the Paramyxoviridae family and Avulovirus genus that includes nine serotypes (APMV 1 to 9). Avian adenoviruses belong to the Adenoviridae family and Aviadenovirus genus. In pigeons, cause classical adenovirosis and necrotizing hepatitis. The respiratory and enteric tracts are common targets of coronavirus. They belong to the Coronaviridae family and to 3a and 3c groups. In this study, we described the presence of viral agents in free-living pigeon feces (Columba livia) from the city of São Paulo, Brazil. The feces were processed by negative staining technique (rapid preparation) for transmission electron microscopy. In this technique paramyxoviruses particles, pleomorphic, roughly spherical or filamentous, measuring 100 to 500 nm of diameter containing an envelope covered by spikes, with characteristic helical herring-bone-like nucleocapsid, measuring 15 to 20 nm in diameter, were visualized in 45 (79 percent) out of 57 feces samples. In 2 (3.5 percent) samples, paramyxovirus and adenovirus particles were simultaneously visualized. Adenovirus particles were isometric, spherical, characterized as "complete "or" empty ", measuring between 70 and 90 nm in diameter. Paramyxovirus and coronavirus particles were detected in 3 (5.2 percent) samples. Coronaviruses were pleomorphic with a diameter of 75-160 nm containing a solar corona-shaped envelope, with projections of approximately 20 nm of diameter. Seven (12.3 percent) samples were negative for viral particles.

Los heces de las palomas constituyen vehículos de enfermedades importantes, tanto para el Hombre como para otras especies animales. En estas aves, las enfermedades virales más importantes del tracto digestivo son transmitidas por los paramixovirus, adenovirus y coronavirus. Paramixovirus aviario, en todo el mundo, ha sido aislado de una variedad de especies de vida libre y de aves domésticas, que causan variados síntomas y señales clínicas con pérdidas económicas. El Paramixovirus pertenece a la familia Paramyxoviridae y al género Avulavirus que incluye nueve serotipos (APMV 1 a 9). Adenovirus aviario pertenece al género de la familia Adenoviridae y género Aviadenovirus. En las palomas, causan la adenovirosis clásica y la hepatitis necrotizante. El tracto respiratorio y entérico son los albos comunes de los coronavirus. Ellos pertenecen a la familia Coronaviridae y a los grupos 3a y 3c. En este trabajo, se describe la presencia de agentes virales en las heces de palomas de vida libre (Columba livia) en la ciudad de São Paulo, Brasil. Las heces se procesaron para la técnica de microscopía electrónica de transmisión, a través de la técnica de contrastación negativa (preparación rápida). A través de esta técnica fueron visualizadas las partículas de paramixovirus, pleomórficas, más o menos esféricas o filamentosas, de 100 a 500 nm de diámetro que contiene un envoltorio cubierto con espículas, con nucleocapside con características helicoidales, midiendo de 15 a 20 nm de diámetro en 45 (79 por ciento) de 57 muestras. En 2 (3,5 por ciento) muestras, fueron observadas simultáneamente partículas de paramixovirus y de adenovirus. Las partículas de adenovirus eran isométricas, esféricas, caracterizadas como “completa " o “vacía ", midiendo entre 70 y 90 nm de diámetro. Fueron analizadas en tres muestras (5,2 por ciento) las partículas de paramixovirus y coronavirus. Los coronavirus son pleomórficos, con un diámetro de 75 a 160 nm, que contiene un capa en forma de corona solar con proyecciones de aproximadamente 20 nm de diámetro. Siete (12,3 por ciento) muestras fueron negativas para las partículas virales.
Descritores: Columbidae
Adenoviridae/isolamento & purificação
Avulavirus/isolamento & purificação
Coronavirus/isolamento & purificação
Fezes/virologia
-Adenoviridae/ultraestrutura
Avulavirus/ultraestrutura
Coronavirus/ultraestrutura
Microscopia Eletrônica de Transmissão
Limites: Animais
Responsável: CL1.1 - Biblioteca Central


  5 / 53 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Chile
Texto completo
Id: biblio-902584
Autor: Villavicencio, Francisca; Valladares, Macarena.
Título: Adenovirus 36 y su potencial contribución en el desarrollo de obesidad / The potential contribution of adenovirus 36 to the development of obesity
Fonte: Rev. méd. Chile;145(8):1054-1059, ago. 2017.
Idioma: es.
Resumo: The evidence of the last 20 years shows a link between viral infections and obesity in animals and humans. There are five adenovirus which have been associated with development of obesity in animals. SMAM-1 virus was the first studied in humans associated with obesity. There is compelling evidence that Ad-36 virus could contribute to the development of obesity in humans and it is related with body mass index (BMI). This manuscript reviews the association between Ad-36 and the other four virus infections with obesity. An electronic search of articles in the databases PubMed and Scielo, with use of key words: obesity, infection, adipose tissue, Ad-36, 3T3-L1 was performed. The search was restricted "human" and "animals". The importance of the relationship between virus infections and obesity has increased over the past two decades. Ad-36 shows more compelling evidence in humans. There are reports involving this virus in the enhancement of adipogenesis, adipocyte differentiation, a lower secretion of leptin and an increased insulin sensitivity. Future work should focus in larger cohort studies to confirm this association, which explains the global obesity epidemic from a new perspective.
Descritores: Adenoviridae/patogenicidade
Infecções por Adenoviridae/complicações
Obesidade/virologia
-Índice de Massa Corporal
Tecido Adiposo/virologia
Fatores de Risco
Limites: Humanos
Animais
Tipo de Publ: Revisão
Responsável: CL1.1 - Biblioteca Central


  6 / 53 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Chile
Texto completo
Id: biblio-1004341
Autor: Fica, Alberto; Cataldo, Pabla; Aceituno, Diana; Villarroel, María Ignacia; Escalona, Arturo.
Título: Fatal nosocomial hemorrhagic enterocolitis probably caused by adenovirus: report of one case / Enterocolitis hemorrágica fatal nosocomial probablemente causada por adenovirus: informe de un caso
Fonte: Rev. méd. Chile;147(2):256-260, Feb. 2019. graf.
Idioma: en.
Resumo: ABSTRACT Adenovirus (ADV) is a recognized cause of severe disease among immunocompromised patients. We report a previously healthy 39-year-old female, admitted with influenza pneumonia and evolving with lung hemorrhage and acute renal failure requiring mechanical ventilation and hemodialysis. She received high corticosteroid doses due to an initial suspicion of alveolar hemorrhage. Lymphopenia already present before steroid use (567/μL), was maintained during the whole hospital stay (mean 782/μL). From the second week of admission she presented a high-volume diarrhea (mean 2.5 L/day) associated to intermittent bloody stools. An ulcerative enterocolitis was confirmed by CT images and colonoscopy. ADV was detected in a colonic tissue sample by real time PCR but not by a commercial filmarray test. Cidofovir-probenecid and racecadotril therapy were indicated without changing the clinical course of diarrhea and the patient finally died.

Adenovirus (ADV) es una causa reconocida de enfermedades graves en pacientes inmunocomprometidos. Informamos el caso de una mujer de 39 años, previamente sana, que ingresó por neumonía grave por influenza, evolucionando con hemorragia pulmonar y falla renal aguda, requiriendo ventilación mecánica y hemodiálisis. Recibió altas dosis de corticoides por la sospecha inicial de una hemorragia alveolar. Tuvo linfopenia durante toda su estadía (promedio 782/μL), la que ya estaba presente antes del uso de los corticoides (567/μL). Desde la segunda semana de hospitalización, presentó una diarrea de alto volumen (promedio 2,5 L/día) asociada a la presencia de sangre en deposiciones en forma intermitente. Se confirmó una enterocolitis ulcerativa por tomografía computada y colonoscopía. Se detectó ADV en muestras de biopsia colónica por PCR en tiempo real pero no por un test de PCR múltiples automatizado comercial. Fue tratada con cidofovir-probenecid y racecadrotrilo sin impacto clínico y la paciente finalmente falleció.
Descritores: Infecção Hospitalar/etiologia
Hospedeiro Imunocomprometido
Infecções por Adenoviridae/complicações
Enterocolite/etiologia
Hemorragia Gastrointestinal/etiologia
-Adenoviridae/isolamento & purificação
Infecção Hospitalar/diagnóstico
Infecção Hospitalar/imunologia
Evolução Fatal
Infecções por Adenoviridae/microbiologia
Diarreia/complicações
Enterocolite/diagnóstico
Enterocolite/imunologia
Hemorragia Gastrointestinal/diagnóstico
Hemorragia Gastrointestinal/imunologia
Limites: Humanos
Feminino
Adulto
Tipo de Publ: Relatos de Casos
Responsável: CL1.1 - Biblioteca Central


  7 / 53 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-952839
Autor: Tamura, Rodrigo Esaki; de Luna, Igor Vieira; Lana, Marlous Gomes; Strauss, Bryan E.
Título: Improving adenoviral vectors and strategies for prostate cancer gene therapy
Fonte: Clinics;73(supl.1):e476s, 2018. graf.
Idioma: en.
Resumo: Gene therapy has been evaluated for the treatment of prostate cancer and includes the application of adenoviral vectors encoding a suicide gene or oncolytic adenoviruses that may be armed with a functional transgene. In parallel, versions of adenoviral vector expressing the p53 gene (Ad-p53) have been tested as treatments for head and neck squamous cell carcinoma and non-small cell lung cancer. Although Ad-p53 gene therapy has yielded some interesting results when applied to prostate cancer, it has not been widely explored, perhaps due to current limitations of the approach. To achieve better functionality, improvements in the gene transfer system and the therapeutic regimen may be required. We have developed adenoviral vectors whose transgene expression is controlled by a p53-responsive promoter, which creates a positive feedback mechanism when used to drive the expression of p53. Together with improvements that permit efficient transduction, this new approach was more effective than the use of traditional versions of Ad-p53 in killing prostate cancer cell lines and inhibiting tumor progression. Even so, gene therapy is not expected to replace traditional chemotherapy but should complement the standard of care. In fact, chemotherapy has been shown to assist in viral transduction and transgene expression. The cooperation between gene therapy and chemotherapy is expected to effectively kill tumor cells while permitting the use of reduced chemotherapy drug concentrations and, thus, lowering side effects. Therefore, the combination of gene therapy and chemotherapy may prove essential for the success of both approaches.
Descritores: Neoplasias da Próstata/terapia
Terapia Genética/métodos
Adenoviridae/genética
Carcinoma Pulmonar de Células não Pequenas/genética
Vetores Genéticos/uso terapêutico
Neoplasias Pulmonares/genética
-Neoplasias da Próstata/genética
Neoplasias da Próstata/imunologia
Proteína Supressora de Tumor p53/biossíntese
Antígeno Prostático Específico/genética
Genes Transgênicos Suicidas
Proteínas de Neoplasias/genética
Limites: Humanos
Masculino
Tipo de Publ: Research Support, Non-U.S. Gov't
Revisão
Responsável: BR1.1 - BIREME


  8 / 53 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-1131851
Autor: Nichols, Larry; Armstrong, Justin; Atkinson, Cody.
Título: The grim reaper evading modern medicine: aspergillosis, adenovirus, and Hodgkin lymphoma
Fonte: Autops. Case Rep;10(4):e2020191, 2020. graf.
Idioma: en.
Resumo: Illustrative cases of diseases that are difficult to suspect and diagnose can serve as useful reminders. Invasive pulmonary aspergillosis and adenovirus hepatitis are two such diseases, both revealed by autopsy in this case of Hodgkin lymphoma refractory to chemotherapy treated with allogeneic hematopoietic stem cell transplantation complicated by these two fatal infections. This patient was cured of Hodgkin lymphoma, Clostridioides difficile colitis and thrombotic thrombocytopenic purpura using the marvels of modern medicine. This case illustrates many features of aspergillosis and adenovirus hepatitis, shows the value of autopsy in revealing diagnoses, and illustrates the limits of modern medicine, which should serve as a mental spur in our efforts to advance medical science, to try to defeat the numerous demons of disease, who seem to keep outwitting us.
Descritores: Doença de Hodgkin/complicações
Adenoviridae
Aspergilose Pulmonar Invasiva/patologia
Hepatite
-Autopsia
Limites: Humanos
Masculino
Adulto
Tipo de Publ: Relatos de Casos
Responsável: BR26.7 - Serviço de Biblioteca e Documentação Científica


  9 / 53 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-888889
Autor: Akçay, Emine; Çarhan, Ahmet; Hondur, Gözde; Tufan, Zeliha Koçak; Duru, Necati; Kılıç, Selçuk; Ensari, Ezgi Naz; Uğurlu, Nagihan; Çağıl, Nurullah.
Título: Molecular identification of viral agents associated with acute conjunctivitis: a prospective controlled study
Fonte: Braz. j. infect. dis;21(4):391-395, July-Aug. 2017. tab.
Idioma: en.
Resumo: Abstract Background: Viral conjunctivitis are the most frequent infections in ophthalmology clinics. The diagnosis is usually relying on clinical findings and medical history. However, topical antibiotics are often used unnecessarily addition to symptomatic treatment because of unsure agents. We aimed to detect the Adenovirus, Coxsackievirus and Enterovirus from conjunctiva and pharyngeal samples of patients. Methods: The conjunctiva and pharyngeal samples of the patients with conjunctivitis were taken by Virocult transport media and kept at -80 ºC up to study day. Adenovirus spp, Enterovirus 70 and Enterovirus 71, Coxsackie A24 and Coxsackie A16 were detected by real-time PCR. Samples from healthy health care workers of ophthalmology clinic were used for control group. Results: A total of 176 samples (conjunctival and pharyngeal samples of 62 patient and 26 healthy subjects) were included. The mean age of 34 (55.7%) male and 27 (44.3%) female patients was 34 ± 17. Twenty five (40.3%) of the patients were receiving antibiotic drops at first visit. The main etiologic agent in conjunctival samples was found to be Adenovirus (46/62, 74.2%) followed by Enterovirus 70 (4/62, 6.4%) and Enterovirus 71 (4/62, 6.4%). Coxsackievirus 16 and 24 were also found in 2 patients (1/62 each, 1.6%). Pharyngeal samples were also positive for Adenovirus (20/62, 32.3%), Enterovirus 70 and 71 (7/62, 11.3% and 5/62, 8.1% respectively), Coxsackievirus 16 and 24 (2/62, 3.2% and 1/61, 1.6%). Conclusions: It is very difficult in viral conjunctivitis to make clinical differentiation caused by different agents because of common clinical signs and symptoms. In routine clinical work, the viral conjunctivitis usually related with Adenovirus. But almost one fourth of the patients' conjunctivitis were not related to Adenovirus, which shows the importance of the laboratory diagnostics. True diagnosis plays an important role on prevention of contamination and unnecessary use of antibiotics in viral conjunctivitis.
Descritores: Faringe/virologia
DNA Viral/isolamento & purificação
Adenoviridae/isolamento & purificação
Conjuntivite Viral/virologia
Enterovirus/isolamento & purificação
-Estudos de Casos e Controles
Adenoviridae/classificação
Adenoviridae/genética
Reação em Cadeia da Polimerase
Doença Aguda
Estudos Prospectivos
Enterovirus/classificação
Enterovirus/genética
Limites: Humanos
Masculino
Feminino
Adulto
Tipo de Publ: Ensaio Clínico Controlado
Responsável: BR1.1 - BIREME


  10 / 53 LILACS  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
Id: biblio-1120884
Autor: Veiga, Ana Beatriz Gorini da; Martins, Letícia Garay; Riediger, Irina; Mazetto, Alix; Debur, Maria do Carmo; Gregianini, Tatiana Schaffer.
Título: More than just a common cold: endemic coronaviruses OC43, HKU1, NL63, and 229E associated with severe acute respiratory infection and fatality cases among healthy adults
Fonte: J. med. virol;92(10):1-6, Aug. 2, 2020. tab.
Idioma: en.
Resumo: Respiratory viral infection can cause severe disease and hospitalization, especially among children, the elderly, and patients with comorbidities. In Brazil, the official surveillance system of severe acute respiratory infection (SARI) investigates influenza A (IAV) and B (IBV) viruses, respiratory syncytial virus (RSV), adenovirus (HAdV), and parainfluenza viruses (hPIV 1­3). In Rio Grande do Sul (RS), Brazil, many fatalities associated with SARI between 2013 and 2017 occurred among patients without underlying diseases and for whom the causative agent had not been identified using official protocols. This cross­sectional study analyzed the presence of coronaviruses (HCoV), bocavirus (HBoV), metapneumovirus (hMPV), and rhinovirus in patients who died of SARI despite not having comorbidities, and that were negative for IAV, IBV, RSV, HAdV, and hPIV. Nasopharyngeal aspirates/swabs from patients were used for nucleic acid extraction. The presence of HCoVs OC43, HKU1, NL63, and 229E; HBoV; hMPV; and rhinovirus was assessed by quantitative reverse transcription­polymerase chain reaction. Clinical data were also analyzed. Between 2013 and 2017, 16 225 cases of SARI were reported in RS; 9.8% of the patients died; 20% of all fatal cases were patients without comorbidities and for whom no pathogen was detected using standard protocols. Analysis of 271 of these cases identified HCoV in nine cases; HBoV, hMPV, and rhinovirus were detected in 3, 3, and 10 cases, respectively. Of note, patients infected with HCoV were adults. Results reinforce the importance of including coronaviruses in diagnostic panels used by official surveillance systems because besides their pandemic potential, endemic HCoVs are associated to severe disease in healthy adults.
Descritores: Sistema Respiratório
Coronavirus
Monitoramento Epidemiológico
Infecções
-Pacientes
Rhinovirus
Vírus
Viroses
Adenoviridae
Doença
Síndrome Respiratória Aguda Grave
Influenza Humana
Bocavirus
Limites: Humanos
Masculino
Feminino
Criança
Adolescente
Adulto
Pessoa de Meia-Idade
Idoso
Idoso de 80 Anos ou mais
Adulto Jovem
Responsável: BR1618.1 - CID - Centro de Informação e Documentação



página 1 de 6 ir para página                
   


Refinar a pesquisa
  Base de dados : Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde
WXIS|fatal error|unavoidable|recxref/read|