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Id: biblio-834336
Autor: Lopes, Luiz Carlos; Giusti, André Luis; Inglez, Thaís Daltoé; Raimundo, Elean Lamar; Souza, Gustavo Barbosa de.
Título: Sinoviosarcoma de tornozelo: quarta recidiva / Ankle's synoviosarcoma: fourth relapse
Fonte: Rev. HCPA & Fac. Med. Univ. Fed. Rio Gd. do Sul;30(2):163-165, 2010. ilus.
Idioma: pt.
Resumo: Esse relato apresenta o caso de uma paciente com quarta recidiva de sinoviosarcoma, um sarcoma de partes moles que possui estreita relação com bainhas tendinosas, bursas e cápsulas articulares. A paciente apresentou uma quarta recidiva, sendo necessária a realização da amputação de perna, visto que as cirurgias conservadoras já não aliviam o sofrimento da paciente. O principal objetivo deste relato de caso é apresentar um caso clássico de neoplasia rara, expondo a doença e fazer uma breve revisão da literatura e mostrar sua importância, visto que corresponde a apenas 5% das neoplasias de partes moles.

This report presents the case of a female patient with fourth synoviosarcoma recurrence, a sarcoma of soft parts that have close relationship with tendom sheaths, bursas and articular capsule.The patient present her fourth recurrence, in wich the perfomance of amputation was required, since the conservative surgeriesno longer relieved the patient suffering. The main objective of this case report is to present a classic case of a rare cancer, exposing the disease, and to make a brief review of the literature to show its importance, since it corresponds to only five percent of the cancers of soft parts.
Descritores: Sarcoma Sinovial/diagnóstico
Sarcoma Sinovial/terapia
Tornozelo/patologia
-Amputação
Neoplasias de Tecidos Moles/diagnóstico
Neoplasias de Tecidos Moles/terapia
Prognóstico
Recidiva Local de Neoplasia
Resultado do Tratamento
Limites: Seres Humanos
Feminino
Adulto
Tipo de Publ: Relatos de Casos
Responsável: BR18.1 - Biblioteca FAMED/HCPA


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Id: biblio-986529
Autor: Castrillón, Mauricio Estrada; Mejía Gómez, Catalina; Gil Serrano, Patricia Eugenia; Franco Cano, Mauricio; Carrascoso Arranz, Javier.
Título: Sarcoma sinovial monofásico de tipo fibroblástico. Evaluación diagnóstica por RM y postratamiento mediante ADC: Presentación de un caso / Monophasic Fibroblastic Synovial Sarcoma. Diagnostic and Post-Treatment Assessment by MRI and ADC: Case Report
Fonte: Rev. colomb. radiol;28(4), 2017. ilus.
Idioma: es.
Resumo: El sarcoma sinovial representa entre el 2 al 10 % de todas las malignidades primarias de tejidos blandos, situándose en el cuarto lugar en frecuencia de los sarcomas de tejidos blandos. Es una neoplasia clasificada por la WHO (World Health Organization) bajo la categoría de tumores de diferenciación incierta, considerándose una malignidad entre intermedio y alto grado. El tratamiento estándar es la escisión quirúrgica, sin embargo, por su alta recurrencia y en los casos en que se asocia a metástasis o márgenes positivos después de la resección, se han planteado otros tratamientos como la quimio y radioterapia. La imaginología juega un papel importante en el diagnóstico, la estadificación y evaluación de la respuesta al tratamiento. Nuevas técnicas como el uso de difusión y mapas de ADC (Apparent Diffusion Coefficient, o coeficiente de difusión aparente) en resonancia magnética (RM) son útiles para evaluar las lesiones tumorales y la respuesta al tratamiento. En este artículo se presenta el caso de un paciente con un sarcoma sinovial monofásico, el diagnóstico por imágenes y evaluación del tratamiento mediante técnicas avanzadas de resonancia magnética como la difusión

Synovial sarcomas represent 2 to 10% of all the primary tissue malignancies and occupy the fourth place in the list of most common soft tissue sarcomas. According to the World Health Organization (WHO), this neoplasm is classified under the category of tumors of uncertain differentiation and is considered an intermediate to high-grade malignancy. Although the standard treatment is surgical excision, alternative treatments such as radiotherapy and chemotherapy have been proposed due to its high rate of recurrence in cases when it is associated with metastasis or positive resection margins. Imaging plays a key role in the diagnosis, staging and assessment of treatment of this disease. New techniques in Magnetic Resonance Imaging such as diffusion and Apparent Diffusion Coefficient (ADC) mapping are useful to further characterize these neoplastic lesions and to assess treatment response. In this article we present a patient with monophasic synovial sarcoma in which the use of these new imaging techniques was essential for the diagnosis and evaluation post-treatment.
Descritores: Diagnóstico por Imagem
-Imagem por Ressonância Magnética
Sarcoma Sinovial
Limites: Seres Humanos
Responsável: CO371.9


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Texto completo SciELO Chile
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Id: lil-762627
Autor: García-Morato, Joaquín; Damonte, Alejandro; Rossetti, Noelia S; Arribalzaga, Eduardo B.
Título: Evolución infrecuente de sinoviosarcoma de muslo / Uncommon evolution after excision of a thigh synovial sarcoma
Fonte: Rev. chil. cir;67(5):527-530, oct. 2015. ilus.
Idioma: es.
Resumo: Background: Synovial sarcoma is a soft tissue tumor with a high degree of local and metastatic invasion. Case report: We report a 26 years old smoker woman with a history of a synovial tumor excised from the right thigh, who required a hip prosthesis for a pathological fracture due to metastases. Two years after, a lung metastasis in the left upper lobe was excised and treated with chemo and radiotherapy. Two years later a new lung nodule was found and excised. Pathology confirmed that they were metastases of the primary tumor. Three months after this last excision, the patient is asymptomatic.

Introducción: El sinoviosarcoma es una neoplasia de partes blandas con alto grado de invasión local y producción de metástasis. Caso clínico: Mujer de 26 años con 2 episodios secuenciales de metástasis pulmonar a lo largo de 6 años posterior al tratamiento del tumor primario. Patología de tratamiento muy complejo.
Descritores: Neoplasias Pulmonares/cirurgia
Neoplasias Pulmonares/secundário
Neoplasias de Tecidos Moles/patologia
Sarcoma Sinovial/cirurgia
Sarcoma Sinovial/secundário
-Coxa da Perna
Limites: Seres Humanos
Adulto
Feminino
Tipo de Publ: Relatos de Casos
Responsável: CL1.1 - Biblioteca Central


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Texto completo SciELO Brasil
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Id: lil-720780
Autor: Maia, Daniela Cristina Caetano; Menezes, Carla Kellen da Silva; Bastos, Thales Costa; Ferreira, Luiz Carlos de Lima; Francesconi, Fabio.
Título: Poorly differentiated synovial sarcoma in the wrist - Case report
Fonte: An. bras. dermatol;89(5):816-818, Sep-Oct/2014. graf.
Idioma: en.
Resumo: Synovial sarcomas are rare malignant tumors affecting mainly young adults, presenting as a slow growth mass located in deep soft tissues of extremities, near the joints. In this report a 34-year-old male patient, presented an ulcerovegetative lesion on the right wrist which was completely excised. Histopathology and immunohistochemistry confirmed synovial sarcomas with poorly differentiated cells. This patient presented 11 months later with ipsilateral axillary lymph node metastasis, which emphasizes the unfavorable prognosis of this synovial sarcoma variant. The indolent growth pattern of this sarcoma justifies the well circumscribed initial stages, which progressively infiltrate adjacent structures with lung metastasis (80%) and lymph node involvement (20%) and thus corroborates the importance of early diagnosis and proper treatment.
Descritores: Sarcoma Sinovial/patologia
Pele/patologia
Neoplasias de Tecidos Moles/patologia
Punho
-Biópsia
Imuno-Histoquímica
Limites: Adulto
Seres Humanos
Masculino
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


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Texto completo SciELO Brasil
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Id: lil-709751
Autor: Fonseca, Adriano Santana; Azevedo, Amanda Canário Andrade; Magalhães, Fabíola Moreira; Andrade, Nilvano Alves de.
Título: Synovial Sarcoma in Head and Neck: A Case Report
Fonte: Int. arch. otorhinolaryngol. (Impr.);18(1):87-89, 01/2014.
Idioma: en.
Resumo: Introduction: Synovial sarcoma is a malignant tumor of mesenchymal pluripotent cells. Objectives: We present a case of synovial sarcoma in the posterolateral wall of the oropharynx. Resumed report: The patient, a 23-year-old woman, was admitted with a history of dysphagia and difficulty in breathing for 8 months, resulting in progressive deterioration and onset of snoring, muffled voice, and local pain. An oropharyngeal tumor in the left posterolateral wall touched the base of the ipsilateral tongue. The patient underwent endoscopic pharyngectomy to remove the lesion. Pathologic examination revealed synovial sarcoma with positive margins, and Mohs technique was proposed for margin control. The margins were disease-free, without the need for total laryngectomy. The pharynx was reconstructed with a microvascular forearm flap. The patient developed postoperative stability. Conclusion:  Despite its name, synovial sarcoma is rarely sourced directly from synovial membranes. It is most commonly found in the vicinity of large joints. The location at the head and neck, a location poor in synovial tissue, is unusual. Synovial sarcoma in the head and neck has an aggressive nature and poor prognosis. Resection with negative margins remains the foundation of therapy, which is not so easily achieved in the head and neck. It is important for the otorhinolaryngologist and head and neck surgeon to be familiar with this aggressive tumor, which carries high mortality and morbidity. The appropriate diagnosis and treatment can improve prognosis and patient survival...
Descritores: Transtornos de Deglutição
Neoplasias de Cabeça e Pescoço
Sarcoma Sinovial
-Diagnóstico
Terapêutica
Limites: Seres Humanos
Feminino
Adulto
Tipo de Publ: Relatos de Casos
Responsável: BR66.1 - Divisão de Biblioteca e Documentação


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Texto completo SciELO Brasil
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Id: lil-701278
Autor: Bezerra, Sabrina Godoy; Brandão, Andrea Araújo; Albuquerque, Denilson Campos; Militão, Rochelle Coppo; Hadlich, Marcelo Souza; Azevedo, Clerio Francisco.
Título: Sarcoma pericárdico de células sinoviais: relato de caso e revisão da literatura / Pericardial synovial sarcoma: case report and literature review
Fonte: Arq. bras. cardiol;101(6):e103-e106, dez. 2013. ilus.
Idioma: pt.
Descritores: Neoplasias Cardíacas/patologia
Pericárdio/patologia
Sarcoma Sinovial/patologia
-Ecocardiografia
Evolução Fatal
Neoplasias Cardíacas/cirurgia
Imagem por Ressonância Magnética
Necrose
Invasividade Neoplásica
Prognóstico
Derrame Pericárdico/patologia
Pericárdio/cirurgia
Sarcoma Sinovial/cirurgia
Limites: Adulto
Feminino
Seres Humanos
Tipo de Publ: Relatos de Casos
Revisão
Responsável: BR1.1 - BIREME


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Id: lil-661851
Autor: Romero Rojas, Alfredo Ernesto; Restrepo Escobar, Ligia Inés; Melo-Uribe, Mario Alexánder; Díaz-Pérez, Julio Alexánder.
Título: Sarcoma sinovial digital / Digital Synovial Sarcoma
Fonte: Rev. colomb. cancerol;13(3):175-180, sept. 2009. tab, graf.
Idioma: es.
Resumo: El sarcoma sinovial es una entidad bien definida clínica y morfológicamente y, a pesar de su nombre, es muy raro en las cavidades articulares. Este sarcoma afecta zonas sin relación aparente con las estructuras sinoviales y representa entre el 5% y el 10% de todos los sarcomas de los tejidos blandos. Se encuentra con mayor frecuencia en las extremidades, especialmente en las inferiores, donde tiende a localizarse en la vecindad de las grandes articulaciones; se han informado muy pocos casos de sarcomas sinoviales en las manos o los pies, con una evolución clínica favorable. Así mismo, es más frecuente de 15 a 40 años de edad (con una edad media de 34 años). Este artículo presenta el caso de una mujer adulta a quien se le realizó el diagnóstico histopatológico e inmunohistoquímico de un sarcoma sinovial en el quinto dedo de la mano derecha.

Synovial sarcoma is a clinically and morphologically well defined entity which, in spite of its name, is rare in joint cavities. This sarcoma affects zones without any apparent relation to synovial structures and represents from 5% to 10% of all sarcomas in soft tissues. It is most frequently found in the extremities, especially the lower ones, where it tends to be located in the vicinity of the major articulations; there are very few favorable reports on the clinical evolution of synovial sarcomas in the hands or feet. It is most frequent between the ages of 15 to 40 (median age, 34). This article presents the case of an adult woman who underwent histopathologic and immunohistochemical diagnosis of a synovial sarcoma on the little finger of her right hand.
Descritores: Extremidade Inferior
Sarcoma
Sarcoma Sinovial
-Colômbia
Imuno-Histoquímica/métodos
Limites: Seres Humanos
Adolescente
Adulto
Feminino
Tipo de Publ: Relatos de Casos
Responsável: CO40.1 - Biblioteca Médica


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Texto completo SciELO Brasil
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Id: lil-656260
Autor: Alencar, Mário Henrique Leite de; Boldrini, Domingos; Costa, Aluysio de Mendonça; Oliveira, Antônio Talvane Torres de; Attab, Cyomara Sanches.
Título: Sarcoma sinovial primário do esôfago / Primary synovial sarcoma of the esophagus
Fonte: Rev. Col. Bras. Cir;39(5):441-443, set.-out. 2012. ilus.
Idioma: pt.
Resumo: Synovial sarcomas are uncommon malignant mesenchymal tumors occurring mainly near the joints of the extremities of young adults. Synovial sarcomas are exceedingly rare neoplasms of the digestive tract. We report the first diagnosed case of esophageal synovial sarcoma, highlighting its diagnostic features surgical management and follow-up.
Descritores: Neoplasias Esofágicas
Sarcoma Sinovial
-Neoplasias Esofágicas/patologia
Neoplasias Esofágicas/cirurgia
Sarcoma Sinovial/patologia
Sarcoma Sinovial/cirurgia
Limites: Adolescente
Feminino
Seres Humanos
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


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Texto completo SciELO Chile
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Id: lil-608767
Autor: Torres-Gómez, Francisco Javier; Vázquez-Ramírez, Francisco José; Torres-Olivera, Francisco Javier.
Título: Sarcoma sinovial bifásico pulmonar: presentación de un caso y revisión de la literatura / Biphasic synovial sarcoma of the lung: report of a case and review of the literature
Fonte: Rev. chil. enferm. respir;27(3):203-207, set. 2011. ilus.
Idioma: es.
Resumo: Introduction: Synovial sarcoma is an aggressive neoplasm described in several locations but is uncommon in the lung. Method: We report a case of biphasic synovial sarcoma of the lung stressing the histologic and immunohistochemical characteristics, genetics and differential diagnosis. Results: a biphasic pattern and SYT-SSX translocation were demostrated. Comments: histology and immuno-histochemistry lead to diagnosis most of the times but the typical translocation is definitive.

Introducción: El sarcoma sinovial es una neoplasia agresiva que aun habiendo sido descrita en múltiples localizaciones, resulta sumamente infrecuente en localización pulmonar. Método: Presentamos un caso de sarcoma sinovial bifásico de localización pulmonar haciendo hincapié en sus características histológicas inmunohistoquímicas y genéticas así como en su diagnóstico diferencial. Resultados: La neoplasia mostraba un patrón bifásico bien caracterizado. El estudio genético demostró la translocación SYT-SSX. Comentarios: Si bien la histología y la inmunohistoquímica permiten en la mayoría de los casos el diagnóstico del sarcoma sinovial, es la translocación genética la que define verdaderamente esta entidad.
Descritores: Neoplasias Pulmonares/diagnóstico
Neoplasias Pulmonares/genética
Neoplasias Pulmonares/patologia
Sarcoma Sinovial/diagnóstico
Sarcoma Sinovial/genética
Sarcoma Sinovial/patologia
-Diagnóstico Diferencial
Imuno-Histoquímica
Proteínas de Fusão Oncogênicas
Reação em Cadeia da Polimerase
Translocação Genética
Limites: Seres Humanos
Masculino
Meia-Idade
Tipo de Publ: Relatos de Casos
Responsável: CL1.1 - Biblioteca Central


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Texto completo SciELO Venezuela
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Id: lil-549492
Autor: Pontillo, Humberto; Urbistazu, Jon Paúl; Gadea, Carlos; Gonzáles, Ricardo; Mosquera, Jorge; Briceño, Alejandro.
Título: Sarcoma sinovial monofásico primario de pulmón: reporte de un caso y revisión de la literatura / Single primary synovial sarcoma of the lung: a case report and review of the literature
Fonte: Rev. venez. oncol;20(3):149-155, jul.-sept. 2008. ilus.
Idioma: es.
Resumo: El sarcoma sinovial es una entidad morfológica, clínica y genéticamente distinta y se puede apreciar en cualquier ubicación. Es un tumor mesenquimal de células fusiformes con una diferenciación epitelial variable. No existe una terapia estandarizada, generalmente el tratamiento es quirúrgico, con una resección total de la lesión, aplicándose en algunos casos radioterapia adyuvante. Los sarcomas sinoviales han mostrado quimiosensibilidad a la ifosfamida y a la doxorrubicina con una respuesta aproximada del 24 por ciento. Se presenta caso de una paciente de 32 años de edad quien presenta tumor en lóbulo inferior de pulmón izquierdo. Se le realizan estudios de extensión, paraclínicos y biopsia por punción dirigida por fluoroscopia que reportó neoplasia epitelial maligna poco diferenciada. Se diagnostica como cáncer de pulmón estadío I realizándose lobectomía inferior izquierda cuya biopsia y estudios inmunohistoquímicos diagnostica un sarcoma sinovial monofásico. Evoluciona satisfactoriamente refiriéndose a los servicios de oncología médica y radioterapia para tratamiento adyuvante.

Synovial Sarcoma is morphologic, clinical organization and genetically different and is possible to be appreciated in any location. Is mesenquimal tumor fusiform cell with variable epithelial differentiation. Treatment, standardized therapy does not exist; the treatment is generally surgical, with total resection of the injury, being applied in some cases adjuvant radiotherapy. Synovial sarcomas has shown chemo sensibility to ifosfamide one and doxorrubicin with an approximated answer of 24 %. A case of a patient of 32 years of age appears that presents displays tumor in inferior lobe of left lung. Studies of extension, paraclinics are made to him and biopsy by punction directed by fluoroscopy that reported neoplasia epithelial vitiates little differentiated. It is diagnosed as lung cancer stage I being made left inferior lobotomy whose inmunohystochemestry biopsy and studies diagnose Synovial sarcoma single-phase. It evolves satisfactorily talking about to the services of medical oncology and radiotherapy for adjuvant treatment.
Descritores: Febre/diagnóstico
Neoplasias Pulmonares/cirurgia
Neoplasias Pulmonares/imunologia
Neoplasias Pulmonares/patologia
Pneumonectomia/métodos
Tosse/diagnóstico
-Oncologia
Sarcoma Sinovial/patologia
Limites: Seres Humanos
Adulto
Feminino
Tipo de Publ: Relatos de Casos
Revisão
Responsável: VE1.1 - Biblioteca Humberto Garcia Arocha



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