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Id: biblio-983699
Autor: Caudet-Esteban, Jana; Olmo-García, María Isabel Del; Merino-Torres, Juan Francisco.
Título: Tumor neuroendocrino ileal con síndrome carcinoide de difícil control / Neuroendocrine ileal tumor with difficult to control carcinoid syndrome
Fonte: Acta méd. colomb;43(3):161-164, jul.-set. 2018. graf.
Idioma: es.
Resumo: Resumen Los tumores neuroendocrinos son neoplasias infrecuentes y de abordaje complejo. Actualmente se necesitan más ensayos clínicos aleatorizados para establecer el manejo óptimo de los pacientes afectados por metástasis hepáticas no resecables. Aportamos un caso de TNE metastásico en el que se indicó trasplante hepático por sintomatología derivada del síndrome carcinoide no controlable con el tratamiento médico habitual. (Acta Med Colomb 2018; 43: 161-164).

Abstract Neuroendocrine tumors are infrequent neoplasms with a complex approach. Currently, more randomized clinical trials are needed to establish the optimal management of patients affected by unresectable liver metastases. A case of metastatic NET in which hepatic transplantation was indicated due to symptoms derived from the carcinoid syndrome that cannot be controlled with the usual medical treatment is provided.
Descritores: Tumor Carcinoide
Sistemas Neurossecretores
-Somatostatina
Transplante de Fígado
Metástase Neoplásica
Limites: Humanos
Masculino
Adulto
Tipo de Publ: Relatos de Casos
Responsável: CO70 - Asociación Colombiana de Medicina Interna


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Id: lil-271202
Autor: Fuentes Valdés, Edelberto; Corona Mancebo, Sixto B.
Título: Tumores carcinoides del pulmón / Lung carcinoid tumors
Fonte: Rev. cuba. cir;39(2):115-123, 2000. tab, graf.
Idioma: es.
Resumo: Se presentan los resultados del tratamiento quirúrgico y la supervivencia de 26 pacientes operados por tumores carcinoides del pulmón y seguidos entre 6 meses y 12 años. Veinte y un pacientes (80,8 porciento) se clasificaron como típicos y 5 (19,2 porciento) como atípicos. El promedio de edad de los primeros fue 45,2 años y de los atípicos 60,2. A cada sexo pertenecieron 13 enfermos. El 57,2 porciento de los tumores se localizaron en posición central. Entre los síntomas asociados más frecuentes se hallaban tos, fiebre reciente y disnea y/o dolor torácico. Sólo 4 enfermos se diagnosticaron en período asintomático. Una de las enfermas mostró 3 tumores sincrónicos; un liposarcoma de la espalda, un adenocarcinoma de colon derecho y un carcinoide atípico del pulmón. Sólo se practicaron resecciones conservadoras a 2 enfermos. En el resto se realizó neumectomía (10 casos), lobectomía (12 casos) y bilobectomía (2 casos). No existió mortalidad posoperatoria. Hubo 2 fallecidos en los que la causa de muerte se comprobó que estaba relacionada con la recidiva tumoral. La enferma con 3 tumores diferentes falleció al año de operada, pero no fue posible determinar su causa de muerte. Los 6 pacientes con más de 10 años de operados estaban vivos al cierre del estudio, excepto 2 que fallecieron por causas ajenas al tumor, 1 de ellos a los 9 años de operado. De 19 pacientes con 5 años o más de seguimiento sólo 2 habían fallecido como consecuencia del tumor, lo que representa una supervivencia global del 89,5 porciento, la que ascendió a 93,8 porciento para los tumores típicos y al 75 porciento para los atípicos(AU)

The results of the surgical treatment and of the survival of 26 patients operated from carcinoid tumors of the lung and followed from 6 months to 12 years are presented in this paper. Twenty one patients (80.8 percent) were clasified as typical and 5 (19.2 percent) as typical. The average age for the former group was 45.2 years and of the latter 60.2 years. Thirteen patients were males and and 13 females. 57.2 percent of tumors were centrally positioned. The most frequent related sysmptom were cough, fever, dyspnes and for chest pain. Only 2 patients were diagnosed as asymptomatic. One female patient showed 3 synchronic tumors: a liposarcoma in her back, one adenocarcinoma in the right colon and an atypical carcinoid tumor in the lung. Two conservative resections were applied to the patients whereas ten cases were treated with pneumectomy, 12 patients with lobectomy and other two with bilobectomy. There was no postoperative death; however 2 people died from causes related to a tumoral relapse. The female patient with 3 tumors died one year after the surgery, but it was impossible to determine the cause of her death. The six patients who had survived for over 10 years after their surgeries were still alive at the closing of this study except for 2 who had died from some problems not related to tumors; one of them after 9 years of having been operated on. Of 19 patients with 5 year or more follow-up, only 2 had died as a result of a tumor, which represents a global survival rate of 89.5 percent. The survival rate for typical tumors reached 93.8 percent and for atypical 75 percent(AU)
Descritores: Tumor Carcinoide/cirurgia
Neoplasias Pulmonares/cirurgia
-Taxa de Sobrevida
Limites: Humanos
Masculino
Feminino
Pessoa de Meia-Idade
Responsável: CU1.1 - Biblioteca Médica Nacional


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Texto completo SciELO Brasil
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Id: biblio-896418
Autor: Queiroz, Rodolfo Mendes; Santana, Danilo Brotto Ferreira de; Nastri Filho, Rogério; Landell, Gláucia Aparecida Magnani; Félix, Paulo Roberto; Valentin, Marcus Vinícius Nascimento.
Título: Endobronchial carcinoid tumor: Radiological findings of a clinical case / Tumor carcinoide endobrônquico: aspectos radiológicos em um caso clínico
Fonte: Rev. Assoc. Med. Bras. (1992);64(1):15-18, Jan. 2018. graf.
Idioma: en.
Resumo: Summary We describe the case of a female patient, 21 years old, complaining of dyspnea attacks and wheezing 2 years ago. Chest radiography showed volume loss in the left lower lobe and ipsilateral retrocardiac triangular basal opacity. CT scan showed an extensive solid mass with apex protruding into the left main and lower lobar bronchi, causing distal atelectasis. Histopathological and immunohistochemical study of transbronchial biopsy of the lesion revealed a typical carcinoid tumor, confirmed after tumor resection with total left pneumectomy.

Resumo Descrevemos um caso de paciente do gênero feminino, 21 anos, apresentando crises de dispneia e sibilância há 2 anos. Radiografia torácica evidenciou perda volumétrica do lobo inferior esquerdo e opacidade triangular basal retrocardíaca ipsilateral. Tomografia computadorizada mostrou formação expansiva sólida com ápice protruindo para o interior dos brônquios principal e lobar inferior esquerdos, promovendo atelectasia distal. Estudos anatomopatológico e imuno-histoquímico após biópsia transbrônquica da lesão diagnosticaram um tumor carcinoide típico, confirmado após ressecção tumoral com pneumectomia total esquerda.
Descritores: Tumor Carcinoide/diagnóstico por imagem
Neoplasias Pulmonares/diagnóstico por imagem
-Biópsia
Tumor Carcinoide/patologia
Tomografia Computadorizada por Raios X
Neoplasias Pulmonares/patologia
Limites: Humanos
Feminino
Adulto
Adulto Jovem
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


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Id: lil-486406
Autor: Collado Otero, Juan Carlos; Almeida Varela, Ricardo.
Título: Tumores carcinoides del pulmón: presentación de un caso / Lung carcinoid tumors: a case report
Fonte: Rev. cuba. cir;46(4), oct.-dic. 2007.
Idioma: es.
Resumo: Se presenta el caso de un paciente de 35 años de edad, que acudió a nuestro instituto después de habérsele practicado, hace 6 años en otro hospital, una lobectomía inferior derecha, tras el diagnóstico de hemangioma pulmonar derecho. En esta oportunidad se ingresa nuevamente para estudiar la reaparición de una sombra pulmonar parahiliar derecha. Presentó hemoptisis masiva y se le realizó una neumonectomía derecha de urgencia. El resultado de la biopsia confirmó como diagnóstico definitivo un tumor carcinoide bronquial. Se revisó la literatura que versa sobre las características clínicas, radiológicas y anatomopatológicas de esta enfermedad(AU)

The case of a 35-year-old patient that came to our institute after having been diagnosed right lung hemangioma and having undergone a right inferior lobectomy in another hospital 6 years ago was presented. In this opportunity, she was admitted again to study the reappearance of a right parahiliar lung shadow. She presented massive hemoptisis, and an emergency right pneumonectomy was performed. The result of the biopsy confirmed a bronchial carcinoid tumor as a definitive diagnosis. The literatute that makes reference to the clinical, radiological and anatomopathological characteristics of this disease was reviewed(AU)
Descritores: Pneumonectomia/métodos
Tumor Carcinoide/diagnóstico
Hemoptise/etiologia
Neoplasias Pulmonares/cirurgia
-Literatura de Revisão como Assunto
Limites: Humanos
Masculino
Adulto
Responsável: CU1.1 - Biblioteca Médica Nacional


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Id: lil-515608
Autor: Vázquez Palanco, Julio; Montero Roca, Leticia; Bandera Ruíz, Nancy; Expósito Reyes, Orlando R; Vallés Gamboa, Moraima.
Título: Tumor carcinoide apendicular / Appendiceal carcinoid tumor
Fonte: Rev. cuba. cir;47(4), sept.-dic. 2008.
Idioma: es.
Resumo: El objetivo de este trabajo fue dar a conocer un interesante caso de tumor carcinoide que se presentó con cuadro clínico de apendicitis aguda. El paciente fue un varón de 8 años de edad, al cual se realizó apendicectomía a causa de una apendicitis aguda. El resultado anatomopatológico confirmó un tumor de células endocrinas (argentafinoma, tumor carcinoide) en el tercio distal del órgano, que infiltraba hasta la serosa, y apendicitis aguda supurada. El paciente fue enviado a un servicio de oncohematología para tratamiento oncoespecífico. Por lo inusual de estos tumores en edades tempranas y por lo que puede representar para el niño una conducta no consecuente, decidimos presentar este caso a la comunidad científica nacional e internacional. Es extremadamente importante el seguimiento de los pacientes con apendicitis aguda y de las conclusiones del examen histológico, por lo que puede representar para el niño una conducta inadecuada en una situación como esta(AU)

The objective of this paper was to make known an interesting case of carcinoid tumor that presented a clinical picture of acute appendicitis.The patient was an eight-year-old boy that underwent appendectomy due to an acute appendicitis. The anatomopathological report confirmed an endocrine cell tumor (argentaffinoma, carcinoid tumor) in the distal third of the organ that infiltrated up to the serosa, and acute suppurative appendicitis. The patient was referred to an oncohematology service for oncospecific treatment. As it is a rare tumor at early ages, and taking into account what a inconsequent behavior may represent for the child, it was decided to present this case to the national and international scientific community. The follow-up of the patients with acute appendicitis and of the conclusions of the histological examination is extremely important considering what an inadequate conduct may represent for the child in a situation like this(AU)
Descritores: Apendicectomia/métodos
Neoplasias do Apêndice/cirurgia
Tumor Carcinoide/cirurgia
Limites: Humanos
Masculino
Criança
Tipo de Publ: Relatos de Casos
Responsável: CU1.1 - Biblioteca Médica Nacional


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Id: biblio-832654
Autor: Gomes, Cristiane Tiburtino de Oliveira; Luz, Patricia Ferreira Neves da; Costa, Gabriele Diniz de Franca; Grangeiro, Jéssica Sales; Jeronimo, Hugo Leonardo Carvalho; Pereira, Leila Maria Moreira Beltrão; Vasconcelos, Graciana Bandeira Salgado de; Mello Filho, Roberto Magalhães de.
Título: Doença de Crohn associada a tumor carcinoide gástrico: relato de caso e revisão de literatura / Crohns disease associated with gastric carcinoid tumor: a case report and literature review
Fonte: GED gastroenterol. endosc. dig;35(4):162-165, out.-dez. 2016. ilus.
Idioma: pt.
Resumo: Os tumores carcinoides gástricos são neoplasias raras, derivadas das células enterocromafins e podem associar-se a doenças inflamatórias intestinais, como a doença de Crohn. Atualmente, há aumento da incidência devido a maior realização de endoscopia digestiva alta. A abordagem depende do tipo, tamanho e número de lesões, além da presença de metástases. Este é o relato de caso de um paciente com doença de Crohn associada a tumor carcinoide gástrico.

The gastric carcinoid tumors are rare, derived from the enterochromaffin cells and may be associated with inflammatory bowel diseases such as Crohns disease. Currently, there is increased incidence due to higher performing endoscopy. The approach depends on the type, size, number of lesions and the presence of metastases. This is a case report of a patient with Crohns disease associated with gastric carcinoid tumor.
Descritores: Neoplasias Gástricas
Tumor Carcinoide
Doença de Crohn
Tumores Neuroendócrinos
-Endoscopia do Sistema Digestório
Limites: Humanos
Masculino
Adulto
Tipo de Publ: Relatos de Casos
Responsável: BR9.1 - Biblioteca de Ciências da Saúde Profa. Susana Schimidt


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Id: biblio-1123433
Autor: Dimitroulopoulos, Dimitrios.
Título: Actualización sobre los tumores carcinoides gastrointestinales / Recent advances in diagnosis of gastrointestinal carcinoid tumors
Fonte: Salud(i)ciencia (Impresa) = Salud(i)ciencia (En linea);15(2):531-534, abr. 2007.
Idioma: es.
Resumo: The carcinoid tumor, argentaffinoma, is a member of a very exclusive neoplastic family known as neuroendocrine or amine precursor uptake and decarboxylation (APUD) tumors. Carcinoids have been found to arise from almost every organ and system derived from the primitive endoderm, but most frequently originated from the gastrointestinal tract, accounting for approximately half of all gastrointestinal endocrine tumors. Over 95% of all gastrointestinal carcinoids are located in only three sites: the appendix, rectum and small intestine. Irrespectively to their location, carcinoids are capable of producing various peptides. These tumors may present at different disease stages with either hormonal or hormonalrelated symptoms/syndromes, or without hormonal symptoms and may occur either sporadically or as a part of hereditary syndromes. Their clinical course is often indolent but can also be aggressive and resistant to treatment. This review provides a broad outline of progress that has been made in the elucidation of their clinical and laboratory diagnosis including recent advances in genetics, molecular biology, histopathology, biochemical markers, radiologic and scintigraphic imaging and endoscopy of gastrointestinal carcinoid tumors

Los tumores carcinoides, argentafinomas, son miembros de una familia particular de tumores conocida como familia de tumores neuroendocrinos o del sistema APUD (amine precursor uptake and decarboxilation: captación y descarboxilación de precursores de aminas). Los tumores carcinoides se originan en los órganos y sistemas derivados del endodermo primitivo, pero más frecuentemente en el tracto gastrointestinal, donde representan aproximadamente la mitad de todos los tumores endocrinos gastrointestinales. Más del 95% de todos los carcinoides gastrointestinales se localizan en tres sitios: el apéndice, el recto y el intestino delgado. Independientemente de su localización, los carcinoides pueden sintetizar varios péptidos. Estos tumores pueden presentarse en diferentes estadios patológicos con síntomas o síndromes hormonales o sin ellos, y pueden presentarse en forma esporádica o como parte de síndromes hereditarios. Su evolución clínica suele ser indolente pero también puede ser agresiva y resistente al tratamiento. Esta revisión describe el progreso realizado en el esclarecimiento de su diagnóstico clínico y de laboratorio e incluye avances recientes en genética, biología molecular, histopatología, marcadores bioquímicos, diagnóstico por imágenes radiológico y centellográfico y endoscopia de los tumores carcinoides gastrointestinales
Descritores: Somatostatina
Tumor Carcinoide
Tumores Neuroendócrinos
Trato Gastrointestinal
Neoplasias Gastrointestinais
Limites: Humanos
Tipo de Publ: Relatório Técnico
Responsável: AR392.1 - Biblioteca


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Texto completo SciELO Brasil
Araújo, F. R
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Id: biblio-1129774
Autor: Araújo, F. R; Câmara, B. O. S; Assunção, G. S. M; Pimentel, S. P; Ocarino, N. M; Serakides, R.
Título: Tumor carcinoide na vesícula biliar em cão / Carcinoid gallbladder tumor in a dog
Fonte: Arq. bras. med. vet. zootec. (Online);72(3):1063-1066, May-June, 2020. ilus.
Idioma: pt.
Resumo: Carcinoid is a neoplasia that arises from dispersed cells of the neuroendocrine system. This tumor is uncommon in animals, and its occurrence in the gallbladder is rare. A male Basset Hound dog's corpse was taken to the Univerdade Federal de Minas Gerais to be analyzed by the Veterinary Pathology sector, without a description of its previous history. Necropsy revealed the presence of pale oral, ocular and penile mucous membranes. The gallbladder had a thickened wall and a dilated lumen, which was filled with dark and lumpy bile. Its mucosa had a whitish-red nodule, with solid and friable areas. Microscopically, there was a focal neoplastic proliferation, which wasn't encapsulated and had imprecise limits, which cells were distributed in a solid pattern and separated by a delicate fibrovascular stroma. The neoplastic cells presented oval or round shaped nucleus, which had a chromatin predominantly loose, and one or two nucleoli. Their cytoplasm was moderately abundant, and in most of the cells it was eosinophilic, granular, and had well-defined limits. Using the Grimelius coloration, neoplastic cells' cytoplasmic granules stained brownish or black, confirming the neuroendocrine origin of the neoplasia. Based on the macroscopic and microscopic findings, the diagnosis of a gallbladder carcinoid was established.(AU)
Descritores: Tumor Carcinoide/veterinária
Carcinoma Neuroendócrino/veterinária
Vesícula Biliar/patologia
Neoplasias da Vesícula Biliar/veterinária
Limites: Animais
Masculino
Cães
Tipo de Publ: Relatos de Casos
Responsável: BR68.1 - Biblioteca Virginie Buff D'Ápice


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Id: lil-734444
Autor: Bisero, Elsa; Luque, Graciela; Lombardero, Lorena; Picón, Armando.
Título: Tumor carcinoide pulmonar: A propósito de un caso / The Pulmonary Carcinoid Tumor. A Case Report
Fonte: Rev. am. med. respir;14(3):318-322, set. 2014. ilus.
Idioma: es.
Resumo: El Tumor Carcinoide es un tipo de tumor cancerígeno formado por células neuroendocrinas. Representa el 1 al 2% de todos los tumores. En el pasado, fueron agrupados en una categoría de neoplasias denominada adenomas bronquiales. Se los consideraba benignos o poco agresivos. Se clasifican según su ubicación en centrales y periféricos y de acuerdo a su histología, dependiendo del número de mitosis y la presencia o no de necrosis, en típicos y atípicos. Tienen una gran variedad de presentación clínica, con diferentes grados de agresividad y pronóstico. Generalmente su diagnóstico es tardío. Nuestro objetivo fue presentar un caso pediátrico de Tumor Carcinoide pulmonar, central y típico.

The pulmonary carcinoid tumor (CT) is a type of cancerous tumor composed of neuroendocrine cells. It represents 1 or 2% of all pulmonary tumors. In the past, these tumors were grouped into a category of neoplasias called bronchial adenomas. They are considered benign or little aggressive. They are classified in central and peripheral tumors depending on their location and in histologic typical and atypical tumors depending on the number of mitosis and the presence or absence of necrosis. They have a wide variety of clinical presentation, with different degrees of aggressiveness and prognosis. The diagnosis is usually late. Our purpose was to present a pediatric case of central and typical pulmonary carcinoid tumor.
Descritores: Tumor Carcinoide
Carcinoma Neuroendócrino
Responsável: AR423.1 - Biblioteca


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Id: biblio-959872
Autor: Gutiérrez-Restrepo, Johnayro; Román-González, Alejandro.
Título: Síndrome de Cushing ectópico: revisión de la literatura / Ectopic Cushing Syndrome: A literature review
Fonte: Rev. colomb. cancerol;20(4):175-182, oct.-dic. 2016. ilus, tab.
Idioma: es.
Resumo: El síndrome de Cushing es una enfermedad muy rara pero asociada a una morbimortalidad significativa. Se clasifica como dependiente de la hormona adrenocorticotrópica (ACTH: tumores hipofisiarios y ectópicos) o independiente de ACTH (lesiones de origen adrenal). En la mayoría de los casos, las lesiones responsables del síndrome corresponden a tumores hipofisiarios, seguida de lesiones adrenales y por último de tumores ectópicos (5-15% de todos los casos). En este artículo se hará una revisión de los aspectos epidemiológicos, clínicos, diagnósticos y terapéuticos más importantes de los tumores ectópicos causantes del síndrome de Cushing.

Cushing's syndrome is a very rare disease associated with significant morbidity and mortality. It is classified as adrenocorticotropic hormone (ACTH) dependent (Pituitary and ectopic tumors) or ACTH independent (lesions of adrenal origin). In most cases, pituitary tumors are responsible for the Cushing's syndrome, followed by adrenal lesions and finally by ectopic tumors (5-15% of all cases). This article describes the most important epidemiological, clinical, diagnostic and therapeutic aspects of ectopic tumors causing Cushing's syndrome.
Descritores: Síndrome de ACTH Ectópico
Tumores Neuroendócrinos
Síndrome de Cushing
Síndromes Endócrinas Paraneoplásicas
-Tumor Carcinoide
Limites: Humanos
Tipo de Publ: Revisão
Responsável: CO40.1 - Biblioteca Médica



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