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Id: biblio-1038273 Autor: Pusiol, Teresa. Título: Histogenetic categorization of atypical melanocytic tumor of uncertain biological malignant potential Fonte: An. bras. dermatol;93(4):608-609, July-Aug. 2018. Idioma: en. Resumo: Abstract: Several reports have demonstrated difficulties and lack of agreement in the histopathological diagnosis of particular melanocytic lesions, with problems in their management. A histogenetic approach to the study of these lesions originated the following classification: 1. superficial atypical proliferation significance; 2. melanocytic tumor of uncertain potential; 3. pigmented epithelioid melanocitoma of uncertain potential; 4. microinvasive radial growth phase of uncertain potential. The terminology remains controversial, reflecting the uncertainty of the diagnosis and the biological potential of these atypical melanocytic lesions. Descritores: Neoplasias Cutâneas/diagnóstico Melanócitos/patologia Melanoma/diagnóstico Nevo Pigmentado/diagnóstico -Lesões Pré-Cancerosas Neoplasias Cutâneas/classificação Diagnóstico Diferencial Melanoma/classificação Nevo Pigmentado/classificação Terminologia como Assunto Limites: Seres Humanos Responsável: BR1.1 - BIREME

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Id: biblio-949948 Autor: González-Ramírez, Roger Adrián; Guerra-Segovia, Carolina; Garza-Rodríguez, Verónica; Garza-Báez, Pamela; Gómez-Flores, Minerva; Ocampo-Candiani, Jorge. Título: Dermoscopic features of acral melanocytic nevi in a case series from Mexico Fonte: An. bras. dermatol;93(5):665-670, Sept.-Oct. 2018. tab, graf. Idioma: en. Resumo: Abstract: Background: Pigmented lesions on acral sites are common; clinical differentiation of nevi and early melanoma can be challenging. In these cases, dermoscopy can provide a more accurate diagnosis. Most dermoscopic patterns on acral skin have been described in Asian and European populations, while there are few studies in Latin American populations. Objectives: To determine the frequency of pigmented lesions in volar skin and their dermoscopic patterns in a Mexican population. Methods: An observational, descriptive, cross-sectional study was performed in Hispanic patients with the presence of at least one pigmented lesion on acral skin. Clinical and dermoscopic images were obtained. These were subsequently evaluated independently by two dermatologists trained and experienced in dermoscopy. Results: A total of 582 pigmented lesions on volar skin were diagnosed in 321 patients. Overall, prevalence of acral pigmented lesions on volar skin was 6.8%. For both observers, parallel furrows were the most frequent pattern described, but for observer 2, a lattice-like pattern was prevalent on the toes and a homogeneous pattern on the sides of the feet. There was lower inter-observer agreement, with a kappa index of 0.144. Study limitations: The lesions were not biopsied, so clinical-histological correlation could not be performed. The study did not correlate dermoscopic patterns with age. Conclusions. As previously reported by other authors, parallel furrows were the most frequently found dermoscopic pattern on palmoplantar skin. Descritores: Neoplasias Cutâneas/patologia Dermoscopia Melanoma/patologia Nevo Pigmentado/patologia -Neoplasias Cutâneas/epidemiologia Dedos do Pé/patologia Estudos Transversais Melanoma/epidemiologia México/epidemiologia Nevo Pigmentado/epidemiologia Limites: Seres Humanos Masculino Feminino Lactente Pré-Escolar Criança Adolescente Adulto Meia-Idade Idoso Adulto Jovem Tipo de Publ: Estudo Observacional Responsável: BR1.1 - BIREME

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Id: biblio-949942 Autor: Fernandes, Karen de Almeida Pinto; Martinez, Diana Carolina Salamanca; Nobre, Aretha Brito; Campos-do-Carmo, Gabriella. Título: Collision tumor: pigmented Bowen's disease and seborrheic keratosis Fonte: An. bras. dermatol;93(5):737-739, Sept.-Oct. 2018. graf. Idioma: en. Resumo: Abstract: Bowen's disease is a type of squamous cell carcinoma in situ of the skin. The pigmented form is rare and represents less than 2% of cases. We report a case of a 74-year-old black man with a blackened and asymptomatic leg injury for about 6 months. Clinically, and under dermatoscopy, the injury was suggestive of melanoma or melanoacanthoma, and a definitive diagnosis was made by histopathological examination. Descritores: Neoplasias Cutâneas/patologia Doença de Bowen/patologia Ceratose Seborreica/patologia -Pele/patologia Dermoscopia Diagnóstico Diferencial Melanoma/patologia Limites: Seres Humanos Masculino Idoso Tipo de Publ: Relatos de Casos Responsável: BR1.1 - BIREME

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Id: biblio-949925 Autor: Steglich, Raquel Bissacotti; Cardoso, Silvana; Gaertner, Maria Helena da Costa Naumann; Coelho, Karina Munhoz de Paula Alves; Cestari, Tania Ferreira; Franco, Selma Cristina. Título: Differences in the diagnosis of primary cutaneous melanoma in the public and private healthcare systems in Joinville, Santa Catarina State, Brazil Fonte: An. bras. dermatol;93(4):507-512, July-Aug. 2018. tab. Idioma: en. Resumo: Abstract: Background: Cutaneous melanoma accounts for up to 80% of deaths caused by skin cancer. Diagnostic suspicion and access to medical care and early intervention in suspected cases is vital to the patient's prognosis. Objectives: To compare demographic and histopathological characteristics of primary cutaneous melanoma diagnosed in the public healthcare system (Sistema Único de Saúde SUS) and the private system in Joinville, Santa Catarina State, Brazil. Methods: This cross-sectional retrospective study analyzed primary cutaneous melanoma cases recorded from 2003 to 2014 in the resident population of Joinville. Ethical approval was obtained from the local Research Ethics Committee. Results: 893 cases of primary cutaneous melanoma were identified. Patients in the private system were mostly younger, while there were more elderly patients in the public healthcare system (p <0.001). There was no statistically significant association between type of care (public/private) and gender or presence of multiple primary cutaneous melanomas. Histological diagnosis of superficial spreading melanoma was more common in patients treated in private healthcare, while nodular melanoma was more frequent in patients in the public healthcare system (p <0.001). Mean Breslow depth in patients treated in private healthcare was 1.35mm, compared to 2.72mm in the public system (p <0.001). Study limitations: This was a retrospective study using secondary databases. Conclusions: thin cutaneous melanoma (in situ cutaneous melanoma and Breslow T1) showed the strongest association with the private healthcare system, while thick cutaneous melanoma was more frequent in the public system (Breslow category T3 and T4) (p <0.001). Descritores: Neoplasias Cutâneas/diagnóstico Melanoma/diagnóstico -Prognóstico Neoplasias Cutâneas/patologia Neoplasias Cutâneas/terapia Neoplasias Cutâneas/epidemiologia Brasil/epidemiologia Estudos Transversais Estudos Retrospectivos Setor Público/estatística & dados numéricos Setor Privado/estatística & dados numéricos Melanoma/patologia Melanoma/terapia Melanoma/epidemiologia Estadiamento de Neoplasias Limites: Seres Humanos Masculino Feminino Recém-Nascido Lactente Pré-Escolar Criança Adolescente Adulto Meia-Idade Adulto Jovem Responsável: BR1.1 - BIREME

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Id: biblio-949919 Autor: Eiger, Daniel; Oliveira, Daniel Arcuschin de; Oliveira, Renato Leão de; Sousa, Murilo Costa; Brandão, Mireille Darc Cavalcante; Oliveira Filho, ,Renato Santos de. Título: Complete lymphadenectomy following positive sentinel lymph node biopsy in cutaneous melanoma: a critical review Fonte: An. bras. dermatol;93(4):553-558, July-Aug. 2018. Idioma: en. Resumo: Abstract: Cutaneous melanoma is the solid neoplasia with the highest growing incidence among all tumors. It spreads predictably to the lymphatic vessels and sentinel lymph node, and when the latter is affected the prognosis worsens dramatically. Sentinel lymph node biopsy is considered when thickness of the primary tumor exceeds 1mm and/or when there are adverse features in thinner melanomas. When there is nodal metastasis, current evidence in the literature recommends complete lymphadenectomy, although this procedure has its intrinsic risks (i.e., lymphedema and cellulitis), and there are no published clinical trials proving additional overall survival benefits. The current in-depth literature review thus aims to identify patients that will benefit most from the procedure, including those with the highest likelihood of presenting additional affected lymph nodes in the same nodal basin. The authors also discuss techniques for identification of the sentinel lymph node, false-negative rates, and predictive models for lymph node involvement. In conclusion, complete elective lymphadenectomy should always be discussed on a case-by-case basis when metastases are detected in the sentinel lymph node. Descritores: Neoplasias Cutâneas/cirurgia Neoplasias Cutâneas/patologia Biópsia de Linfonodo Sentinela Melanoma/cirurgia Melanoma/patologia -Excisão de Linfonodo Limites: Seres Humanos Tipo de Publ: Revisão Responsável: BR1.1 - BIREME

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Id: biblio-1038278 Autor: Suzuki, Nathalie Mie; Saraiva, Maria Isabel Ramos; Capareli, Gabriela Cunha; Castro, Luiz Guilherme Martins. Título: Histologic review of melanomas by pathologists trained in melanocytic lesions may change therapeutic approach in up to 41 9% of cases Fonte: An. bras. dermatol;93(5):752-754, Sept.-Oct. 2018. tab, graf. Idioma: en. Resumo: Abstract: Melanoma Guidelines of the Brazilian Dermatology Society recommend histologic review by pathologists trained in melanocytic lesions whenever possible. Out of 145 melanoma cases identified at a private clinic in São Paulo/Brazil, 31 that had been submited to histologic review were studied to evaluate whether revision had led to change in therapeutic approach.. Differences in original/reviewed reports were found in 58.1% (n=18) of the reports, leading to changes in therapeutic approach in 41.9% (n=13). Change in diagnosis was observed in 6 out of 31 (19,3%) cases. These findings suggest that second opinion by pathologists trained in melanocytic lesions is likely to show significant differences from the original report. Descritores: Patologia Clínica/normas Patologistas Melanócitos/patologia Melanoma/patologia -Encaminhamento e Consulta Brasil Variações Dependentes do Observador Estudos Retrospectivos Técnicas Histológicas/métodos Técnicas Histológicas/normas Dermatologia/normas Dermatologistas Melanoma/diagnóstico Melanoma/terapia Estadiamento de Neoplasias/classificação Limites: Seres Humanos Responsável: BR1.1 - BIREME

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Id: biblio-983727 Autor: Rezende, Hudson Dutra; Almeida, Ana Paula Moura de; Shimoda, Eduardo; Milagre, Ana Carolina Xavier; Almeida, Liana Moura de. Título: Study of skin neoplasms in a university hospital: integration of anatomopathological records and its interface with the literature Fonte: An. bras. dermatol;94(1):42-46, Jan.-Feb. 2019. graf. Idioma: en. Resumo: Abstract: Background: Skin cancer is a highly prevalent condition with a multifactorial etiology resulting from genetic alterations, environmental and lifestyle factors. In Brazil, among all malignant tumors, skin cancers have the highest incidences. Objective: To retrospectively evaluate the incidence, prevalence and profile of basal cell carcinoma, squamous cell carcinoma and cutaneous melanoma in Campos dos Goytacazes and region. Methods: In total, 2,207 histopathological reports of a local reference hospital were analyzed between January 2013 and December 2015, of which 306 corresponded to the neoplasms studied. Results: Of the 306 reports evaluated, 232 basal cell carcinomas (75.9%), 55 squamous cell carcinomas (18%) and 19 cutaneous melanomas (6.5%) were identified. The face was the most involved anatomical site (58.8%) and women (51%) were the most affected gender. The temporal analysis revealed a decrease in the overall incidence of 3.4% from 2013 to 2014 and 5.4% from 2014 to 2015. There was a 10.1% increase in basal cell carcinomas and 38% in melanomas in this period; however, there was a decrease in the number of squamous cell carcinomas of 14.8% during the studied years. Study limitations: Some samples of cutaneous fragments had no identification of the anatomical site of origin. Conclusion: Research that generates statistical data on cutaneous tumors produces epidemiological tools useful in the identification of risk groups and allows the adoption of more targeted and efficient future prevention measures. Descritores: Neoplasias Cutâneas/epidemiologia Carcinoma Basocelular/epidemiologia Carcinoma de Células Escamosas/epidemiologia Melanoma/epidemiologia -Neoplasias Cutâneas/patologia Brasil/epidemiologia Carcinoma Basocelular/patologia Carcinoma de Células Escamosas/patologia Registros Médicos Incidência Prevalência Estudos Transversais Estudos Retrospectivos Distribuição por Sexo Distribuição por Idade Hospitais Universitários/estatística & dados numéricos Melanoma/patologia Limites: Seres Humanos Masculino Feminino Meia-Idade Idoso Idoso de 80 Anos ou mais Responsável: BR1.1 - BIREME

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Id: biblio-973632 Autor: Kravvas, Georgios; Ball, Stephanie Louise; Naysmith, Lisa. Título: Assessing the efficacy of a 10-point referral tool in the triaging of pigmented lesions to a Dermatology clinic Fonte: An. bras. dermatol;93(6):932-933, Nov.-Dec. 2018. graf. Idioma: en. Descritores: Encaminhamento e Consulta Neoplasias Cutâneas/diagnóstico Triagem/métodos Melanoma/diagnóstico -Agendamento de Consultas Reprodutibilidade dos Testes Estudos Retrospectivos Limites: Seres Humanos Masculino Feminino Meia-Idade Tipo de Publ: Carta Estudos de Avaliação Responsável: BR1.1 - BIREME

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Id: biblio-973631 Autor: Maia, Marcus; Amadio, Camila Ribeiro; Morales, Andrezza Garcia; Lellis, Rute Facchini. Título: Vertical plane ex vivo dermoscopy: a novel dermoscopic technique. A preliminary study Fonte: An. bras. dermatol;93(6):899-901, Nov.-Dec. 2018. graf. Idioma: en. Resumo: Abstract: Dermoscopic examination allows visualization of horizontal images on the skin, showing well-defined patterns. The authors propose ex vivo dermoscopic visualization using a vertical view of skin sections. The new image clearly distinguishes the stratum corneum, epidermis, and dermis as well as the anatomical location of the pigment. Will this new approach be useful in dermoscopic diagnosis? Further studies are needed. Descritores: Neoplasias Cutâneas/diagnóstico por imagem Dermoscopia/métodos Melanoma/diagnóstico por imagem Nevo Pigmentado/diagnóstico por imagem -Neoplasias Cutâneas/patologia Biópsia Reprodutibilidade dos Testes Diagnóstico Diferencial Melanoma/patologia Nevo Pigmentado/patologia Limites: Seres Humanos Masculino Responsável: BR1.1 - BIREME

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Id: biblio-973622 Autor: Abreu, Marilda Aparecida Milanez Morgado de; Tozo, Jéssica Priscila; Wagner, Amanda Kloster. Título: Conjunctival melanoma Fonte: An. bras. dermatol;93(6):936-937, Nov.-Dec. 2018. graf. Idioma: en. Descritores: Neoplasias da Túnica Conjuntiva/diagnóstico por imagem Melanoma/diagnóstico por imagem -Neoplasias da Túnica Conjuntiva/cirurgia Melanoma/cirurgia Limites: Seres Humanos Feminino Idoso Tipo de Publ: Relatos de Casos Carta Responsável: BR1.1 - BIREME

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