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Texto completo SciELO Cuba
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Id: lil-575486
Autor: Figueroa, Alejandro Yuri; Díaz Anaya, Amnia; Montero Leon, Jorge Felipe; Jiménez Mendes, Lourdes.
Título: Algunos factores pronósticos de interés en el melanoma maligno cutáneo / Some interesting prognostic factors related to cutaneous malignant melanoma
Fonte: Rev. cuba. cir;49(1), ene.-mar. 2010. ilus.
Idioma: es.
Resumo: INTRODUCCIÓN. El objetivo de esta investigación fue determinar el valor pronóstico independiente y la supervivencia entre 3 y 5 años de los factores pronósticos clínico-patológicos más importantes, y en cada etapa, según el sistema de estadificación patológica tumor-nódulo-metástasis (TNM), en pacientes con melanoma maligno cutáneo (MMC). MÉTODOS. Se realizó un estudio retrospectivo, descriptivo y longitudinal, aplicando el modelo de riesgo proporcional de Cox y el método de Kaplan Meier, dirigido a la búsqueda de diferentes variables de riesgo en pacientes con MMC. Se estudiaron 157 casos de pacientes con MMC, atendidos en un intervalo de 8 años (1993 a 2001), diagnosticados y tratados en el Instituto Nacional de Oncología y Radiobiología de La Habana. RESULTADOS. Las variables pronósticas más poderosas relacionadas con la enfermedad localizada (etapa I y II) fueron el espesor de Breslow (P: 0,000), el índice mitótico (P: 0,004), y el nivel de Clark (P: 0,04); entre las variables relacionadas con la enfermedad regional (etapa III) el número de ganglios linfáticos afectados fue la de mayor peso (P: 0,000) y la más importante en la etapa IV fue la metástasis visceral a distancia (P: 0,003). La supervivencia fue descendiendo según avanzaba la etapa patológica de la enfermedad. CONCLUSIONES. Los factores pronósticos independientes más destacados fueron el índice de Breslow, el número de nódulos linfáticos regionales afectados y las metástasis viscerales a distancia, lo cual está avalado por el consenso mundial. Sin embargo, variables como edad, sexo, sitio de la lesión, ulceración, respuesta inflamatoria hospedero-tumor, subtipo histológico, satelitosis y metástasis en tránsito, distinguidas como indicadores pronósticos independientes en grandes casuísticas, no mostraron significación estadística en este trabajo(AU)

INTRODUCTION: The aim of present research was to determine the independent prognostic value and the 3 and 5 years survival of more significant clinicopathological prognostic factors and in each stage, according to pathological staging system of tumor-nodule-metastasis (TNM) in patients with cutaneous malignant melanoma (CMM). METHODS: A longitudinal, descriptive and retrospective study was conducted applying the Cox proportional risk form and the Kaplan-Meier method, aimed to search of different risk variables in patients with CMM. We studied 157 patients with CMM, seen during 8 years (1993 to 2001), diagnosed and treated in National Institute of Oncology and Radiobiology of La Habana. RESULTS: The more powerful prognostic variables related to localized disease (stage I and II) were the Breslow density (P: 0,000), the mitosis rate (P: 0,004), and the Clark level (P: 0,04); among the variables related to the regional disease (stage III) the number of lymphatic ganglia involved was the more weighthy (P:0,000) and the more important in Stage IV was the distant visceral metastasis (P:0,003). Survival was decreasing according to the advance of the pathological stage of disease. CONCLUSIONS: The more involved independent prognostic factors were the Breslow rate, the number of involved regional lymphatic nodules and the distant visceral metastasis, which is endorsed by a world consensus. However, variables as age, sex, lesion site, ulceration, host-tumor inflammatory response, histological subtype, satellitosis and transient metastasis, considered as independent prognostic indicators in big casuistries, had not statistical significance in present paper(AU)
Descritores: Metástase Neoplásica/patologia
Melanoma/epidemiologia
Neoplasias Cutâneas/epidemiologia
-Prognóstico
Epidemiologia Descritiva
Estudos Retrospectivos
Estudos Longitudinais
Limites: Seres Humanos
Responsável: CU1.1 - Biblioteca Médica Nacional


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Id: biblio-887076
Autor: Souza, Nivea Godinho Alves de; Nai, Gisele Alborghetti; Wedy, Gláucia Ferreira; Abreu, Marilda Aparecida Milanez Morgado de.
Título: Congenital plaque-like glomangioma: report of two cases
Fonte: An. bras. dermatol;92(5,supl.1):43-46, 2017. graf.
Idioma: en.
Resumo: Abstract: Glomus tumors are rare hamartomas that originate from the glomus body. These tumors can be divided into solitary and multiple, the latter also known as glomangioma. We report the case of two patients with a rare variety of glomangioma called congenital plaque-like glomangioma. It presents as numerous red to bluish compressible papules, that increase in size in proportion with the weight and height growth of the child. Diagnostic confirmation is with histopathology and the treatment is surgical.
Descritores: Neoplasias Cutâneas/congênito
Tumor Glômico/congênito
Tumor Glômico/patologia
-Neoplasias Cutâneas/patologia
Telangiectasia/congênito
Telangiectasia/patologia
Doenças Raras/congênito
Doenças Raras/patologia
Limites: Seres Humanos
Feminino
Adulto
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


  3 / 2233 LILACS  
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Id: biblio-887074
Autor: Godinho, Nivea; Nai, Gisele Alborghetti; Schaefer, Arnaldo Luiz Flávio; Schaefer, Luiza Vasconcelos.
Título: Kissing nevus of the penis: a case report and dermatoscopic findings
Fonte: An. bras. dermatol;92(5,supl.1):95-97, 2017. graf.
Idioma: en.
Resumo: Abstract Divided nevus, also known as kissing nevus, is a rare variant of congenital melanocytic nevi in which there are two adjacent nevi in areas of the body that undergo embryonic cleavage. The original description of this type of lesion was on the eyelid. The location on the penis is even rarer, with only 17 case reports in the literature so far, and only one of them described the dermoscopic findings. We report the case of a patient with divided nevus of the penis and its clinical, dermoscopic and histopathological features.
Descritores: Neoplasias Penianas/patologia
Neoplasias Cutâneas/patologia
Nevo Pigmentado/patologia
-Pênis/patologia
Dermoscopia
Melanócitos/patologia
Limites: Seres Humanos
Masculino
Criança
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


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Id: biblio-887072
Autor: Vasconcelos, Erica Rodrigues de Araujo; Bauk, Alexander Richard; Rochael, Mayra Carrijo.
Título: Cutaneous myeloid sarcoma associated with chronic myeloid leukemia
Fonte: An. bras. dermatol;92(5,supl.1):50-52, 2017. graf.
Idioma: en.
Resumo: Abstract: Myeloid sarcoma is an extramedullary tumor of malignant myeloid cells often associated with acute myeloid leukemia, chronic myeloproliferative disorders and myelodysplastic syndromes. The skin is one of the most commonly affected sites. We report a rare case of cutaneous myeloid sarcoma associated with chronic myeloid leukemia.
Descritores: Neoplasias Cutâneas/patologia
Leucemia Mielogênica Crônica BCR-ABL Positiva/patologia
Sarcoma Mieloide/patologia
Neoplasias Primárias Múltiplas/patologia
-Pele/patologia
Biópsia
Medula Óssea/patologia
Imuno-Histoquímica
Doenças Raras/complicações
Doenças Raras/patologia
Limites: Seres Humanos
Feminino
Adulto
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


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Id: biblio-887068
Autor: Malveira, Maria Isabel Braga; Pascoal, Gianne; Gamonal, Shirley Braga Lima; Castañon, Maria Christina Marques Nogueira.
Título: Folliculotropic mycosis fungoides: challenging clinical, histopathological and immunohistochemical diagnosis
Fonte: An. bras. dermatol;92(5,supl.1):73-75, 2017. graf.
Idioma: en.
Resumo: Abstract Mycosis fungoides is a cutaneous T-cell lymphoma with various clinical and pathological presentations. Early lesions are nonspecific, which hinders early diagnosis. The folliculotropic subtype is manifested as acneiform lesions, follicular papules or erythematous plaques mainly on the face, neck and upper trunk. Histopathology shows dense lymphocytic infiltrate surrounding and infiltrating the hair follicles. A case of difficult histopathological diagnosis with florid and unusual skin lesions mainly on the face is reported.
Descritores: Pele/patologia
Micose Fungoide/patologia
-Neoplasias Cutâneas/patologia
Biópsia
Imuno-Histoquímica
Limites: Seres Humanos
Masculino
Meia-Idade
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


  6 / 2233 LILACS  
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Id: biblio-887066
Autor: Umbert-Millet, Pablo; Quintana-Codina, Monica; Salleras-Redonnet, Montse.
Título: Melanoma in situ and syringoma: a rare collision tumor. Clinical-pathological report of a case
Fonte: An. bras. dermatol;92(5,supl.1):101-103, 2017. graf.
Idioma: en.
Resumo: Abstract Collision or contiguous tumors, defined as two or more distinct tumors occurring at one site, are often an unexpected finding and may represent a diagnostic challenge, as clinical and histological presentations do not always coincide. Various combinations of collision tumors have been described with respect to melanocytic lesions, with the most frequently reported being the combination of nevus and basal cell carcinoma. We present an unusual case on the nose involving a melanoma in situ and a clinically-inapparent syringoma, which, to the best of our knowledge, is the first report of this combination.
Descritores: Neoplasias Cutâneas/patologia
Neoplasias das Glândulas Sudoríparas/patologia
Siringoma/patologia
Melanoma/patologia
-Biópsia
Imuno-Histoquímica
Neoplasias Primárias Múltiplas
Limites: Seres Humanos
Masculino
Idoso de 80 Anos ou mais
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


  7 / 2233 LILACS  
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Id: biblio-887064
Autor: Diani, Marco; Turina, Marco; Cozzi, Chiara; Altomare, Gianfranco.
Título: Acquired lymphangiomas mimicking multiple hallux warts
Fonte: An. bras. dermatol;92(5,supl.1):11-13, 2017. graf.
Idioma: en.
Resumo: Abstract: Lymphangioma is an uncommon benign vascular tumour that involves lymphatic vessels. It can be acquired or, most frequently, congenital. The acquired form presents with dilated lymphatic channels due to an obstruction. These lesions have no risk of malignant transformation, but they have a high rate of recurrence whether removed. We present a case of a 52-year-old woman with acquired lymphangiomas mimicking warts. She came to our observation for some keratotic lesions on her feet. Clinically, we found three warts on the sole of her left foot, but we also noticed the presence of swelling and papillomatous wart-like papules on both halluces. The hallux papules were studied by performing an excisional biopsy and were found to be lymphangiomas.
Descritores: Neoplasias Cutâneas/patologia
Verrugas/patologia
Hálux/patologia
Linfangioma/patologia
-Biópsia
Vasos Linfáticos/patologia
Diagnóstico Diferencial
Limites: Seres Humanos
Feminino
Meia-Idade
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


  8 / 2233 LILACS  
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Id: biblio-887062
Autor: Brito, Priscilla Kelly Soares Torres; Fernandes, Victor Miguel Coutinho; Brito, Humberto David Menezes de Siqueira; Azzouz, Mohamed Arbaqui; Souza, Anélia Carneiro; Fernandes, Klécius Leite.
Título: Periorbital leiomyosarcoma treated by means of conventional surgery and frontal myocutaneous flap
Fonte: An. bras. dermatol;92(5,supl.1):118-120, 2017. graf.
Idioma: en.
Resumo: Abstract Cutaneous leiomyosarcoma is a rare neoplasia, and its periorbital presentation is rather uncommon. We present a case of a male patient who was surgically treated, with the reconstruction performed with a frontal myocutaneous flap. The patient has been followed up for one year with adequate oncologic control and good aesthetic outcome.
Descritores: Neoplasias Cutâneas/cirurgia
Retalho Miocutâneo/transplante
Leiomiossarcoma/cirurgia
-Órbita
Neoplasias Cutâneas/patologia
Biópsia
Imuno-Histoquímica
Resultado do Tratamento
Leiomiossarcoma/patologia
Limites: Seres Humanos
Masculino
Adulto
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


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Id: biblio-887056
Autor: González-Guerra, Elena; Rodriguez, Jorge Ruiz; Casado, Alejandro Fueyo; Taboada, Alberto Conde; Toro, Jose Antonio Cortes; Bran, Eduardo Lopez.
Título: Bilateral clear cell acanthoma of the areola and nipple: good response to topical corticosteroids
Fonte: An. bras. dermatol;92(5,supl.1):27-29, 2017. graf.
Idioma: en.
Resumo: Abstract: Clear cell acanthoma is a rare, epidermal tumor not common in the area of the nipples; indeed, the literature describes only 8 cases, all showing unilateral presentation. We here report the first case of bilateral clear cell acanthoma with good response to topical corticosteroids. Case report: A sixteen-year old girl presented with 2 excrescent, fleshy, and exudative tumor masses in both nipples and areola mammae. A biopsy was conducted and confirmed clear cell acanthoma histopathologically. Treatment with strong corticosteroids resulted in rapid improvement and resolution. After one year of follow-up, the patient developed atopic dermatitis. Discussion: We describe the first case of bilateral clear cell acanthoma localized in the nipple/areola that resolved with powerful corticosteroids, suggesting a reactive etiology of the lesion.
Descritores: Neoplasias Cutâneas/patologia
Neoplasias Cutâneas/tratamento farmacológico
Clobetasol/administração & dosagem
Acantoma/patologia
Acantoma/tratamento farmacológico
Glucocorticoides/administração & dosagem
Neoplasias Primárias Múltiplas/patologia
Neoplasias Primárias Múltiplas/tratamento farmacológico
Mamilos/patologia
-Biópsia
Administração Tópica
Resultado do Tratamento
Limites: Seres Humanos
Feminino
Adolescente
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


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Id: biblio-887052
Autor: Costa, Eline Pinheiro Weba; Lucena, Bethänia Dias de; Amin, Gabriela Athayde; Bittencourt, Maraya de Jesus Semblano; Dias Junior, Leonidas Braga; Pires, Carla Andréa Avelar.
Título: Primary cutaneous follicle center lymphoma
Fonte: An. bras. dermatol;92(5):701-703, Sept.-Oct. 2017. graf.
Idioma: en.
Resumo: Abstract: Cutaneous lymphomas are classified according to their cellular origin into T-cell lymphoma and B-cell lymphoma. The annual incidence rate is 0.3 per 100,000 population. We report a case of a 56-year-old male patient who presented with a two-month history of nodules of varying sizes, some ulcerated, on the face, abdomen, and upper limbs. Histopathological examination and immunohistochemical study confirmed the diagnosis of primary cutaneous centrofollicular lymphoma. Studies have shown an increased incidence of non-Hodgkin lymphomas in the last decade. We report an infrequent case that should be kept as a differential diagnosis of patients with nodules and cutaneous papules.
Descritores: Neoplasias Cutâneas/patologia
Linfoma Folicular/patologia
-Neoplasias Cutâneas/tratamento farmacológico
Biópsia
Imuno-Histoquímica
Linfoma Folicular/tratamento farmacológico
Limites: Seres Humanos
Masculino
Meia-Idade
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME



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