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Texto completo SciELO Chile
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Id: biblio-978165
Autor: Ocampo T, Wilmar; Poyo C, José Carlos; Manzano P, María Teresa; Jover S, Juan José; Guadaño S, Vicente.
Título: Angiomiofibroblastoma-like, un tumor excepcional: presentación de un caso clínico y diagnóstico diferencial / Angiomyofibroblastoma-like, an exceptional tumor: presentation of a clinical case and differential diagnosis
Fonte: Rev. chil. radiol;24(3):117-124, jul. 2018. tab, ilus.
Idioma: es.
Resumo: Presentamos un caso de Angiomiofibroblastoma-like (AML), en el que la ecografía fue importante para determinar la detección, localización y extensión local. Hallazgos: La ecografía demostró una lesión paratesticular sólida hipoecogénica de bordes bien definidos lo que sugirió lesión benigna extratesticular. La histología evidenció una neoplasia mesenquimal benigna tipo mixoide en cuyo diagnóstico diferencial se incluyen el Angiomixoma superficial (AMS), Angiomixoma agresivo (AMA), Angiomiofibroblastoma (AMF) y el AML. En base a estos hallazgos se realizó una revisión de tumores de similares características en la literatura, llegando finalmente al diagnóstico de AML cuya localización paratesticular sólo ha sido descrita en muy pocos casos hasta la fecha. Conclusión: La ecografía es útil para localizar los tumores paratesticulares y determinar su extensión local. No obstante, para llegar al diagnóstico definitivo es necesario realizar un estudio histológico e inmunohistoquímico de la tumoración.

We present a case of a paratesticular Angiomiofibroblastoma-like (AML) tumor in which ultrasound was important to give the specific location and local extension of the lesion. Findings: Ultrasound revealed a hypoechoic paratesticular lesion with well-defined borders, suggesting an extratesticular benign lesion. The histology showed a benign mesenchymal myxoid-type neoplasm. The differential diagnosis included superficial Angiomyxoma (AMS), Aggressive angiomyxoma (AMA), Angiomyofibroblastoma (AMF) and AML. Based on these findings, a review of similar tumors was carried out and ultimately led to the diagnosis of paratesticular AML. This location has been described only in a few cases in the literature. Conclusion: Ultrasound is useful to locate paratesticular tumors and determine their local extension. However, a definitive diagnosis still requires a histological and immunohistochemical study.
Descritores: Angiofibroma/cirurgia
Angiofibroma/diagnóstico por imagem
Neoplasias dos Genitais Masculinos/cirurgia
Neoplasias dos Genitais Masculinos/patologia
-Imuno-Histoquímica
Tomografia Computadorizada por Raios X
Ultrassonografia
Angiofibroma/patologia
Diagnóstico Diferencial
Limites: Seres Humanos
Masculino
Meia-Idade
Tipo de Publ: Relatos de Casos
Revisão
Responsável: CL30.1 - Biblioteca


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Id: biblio-910951
Autor: Athanazio, DA; Trpkov, K.
Título: What is new in Genitourinary Pathology? Recent developments and highlights of the new 2016 World Health Organization classification of tumors of the urinary system and male genital organs
Fonte: Appl. cancer res;36:1-11, 2016. ilus.
Idioma: en.
Resumo: The recently published 2016 World Health Organization (WHO) Classification of Tumors of the Urinary System and Male Genital Organs stems from the accumulated knowledge and data collected during the last 12 years, since the previous edition of the WHO "blue book" 2004. The major changes in prostate pathology include the introduction of a novel grading system for prostate cancer (Grade Groups/International Society of Urological Pathology (ISUP) grades 1­5), the recognition of intraductal carcinoma as a new entity, and the terminological changes regarding the neuroendocrine prostatic neoplasms. In bladder and urothelial tract, within the spectrum of flat and non-invasive lesions, a newly introduced term "urothelial proliferation of uncertain malignant potential" replaced the term "urothelial hyperplasia", and the term "urothelial dysplasia" was better defined. A category of "invasive urothelial carcinoma with divergent differentiation" was introduced for tumors showing a component of "usual type" urothelial carcinoma combined with other morphologies. A new WHO/ISUP renal tumor grading system was recommended (Grade 1­4). The definition of renal papillary adenoma was modified and expanded to include papillary neoplasms measuring up to 1.5 cm. Several new epithelial renal tumors were recognized as new entities including: hereditary leiomyomatosis and renal cell carcinoma (RCC) syndrome­associated RCC, succinate dehydrogenase­deficient RCC, tubulocystic RCC, acquired cystic disease­associated RCC, and clear cell papillary RCC. In testis pathology, intratubular proliferations of testicular germ cell tumors were renamed as "germ cell neoplasia in-situ" (GCNIS), and the testicular neoplasms were divided into two main groups: derived from or unrelated to GCNIS. A major change in penile pathology was the introduction of a new classification of penile squamous cell carcinoma, based on the presence of human papillomavirus (HPV), which characterizes penile tumor subtypes as HPV-related or non-HPV-related. A similar distinction was introduced for the preneoplastic penile intraepithelial precursor lesion (PeIN) into non-HPV related (differentiated PeIN) and HPV-related types (undifferentiated PeIN). In this review, we provide a summary and highlight the changes in the genitourinary pathology introduced by the 2016 WHO blue book, and we also discuss some recent developments that may impact the practice of genitourinary pathology in the near future (AU)
Descritores: Neoplasias dos Genitais Masculinos/classificação
Classificações em Saúde
Neoplasias Renais/classificação
Neoplasias Penianas/classificação
Neoplasias da Próstata/classificação
Neoplasias Testiculares/classificação
Neoplasias da Bexiga Urinária/classificação
Neoplasias Urogenitais/patologia
Neoplasias Urológicas/classificação
Limites: Seres Humanos
Masculino
Tipo de Publ: Revisão
Responsável: BR30.1 - Biblioteca


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Id: biblio-836206
Autor: Symington, Banu.
Título: La epidemia silenciosa de cancer asociado a HPV y como prevenirla: Mensajes para los profesionales, pacientes y padres de mi comunidad / The silent epidemic of cancer associated with HPV and how to prevent it: messages for professionals, patients and parents in my community
Fonte: Rev. med. Rosario;82(2):55-57, may.-ago. 2016.
Idioma: es.
Descritores: Infecções por Papillomavirus/prevenção & controle
PAPILLOMAVIRUS HUMANO 1ABDOMINAL NEOPLASMS
PAPILLOMAVIRUS HUMANO ABNORMALITIES, MULTIPLE
-Alphapapillomavirus
Neoplasias do Ânus
Doenças Virais Sexualmente Transmissíveis/prevenção & controle
Doenças Sexualmente Transmissíveis/prevenção & controle
Estados Unidos/epidemiologia
Neoplasias dos Genitais Femininos
Neoplasias dos Genitais Masculinos
Neoplasias Bucais
Vacinas contra Papillomavirus
Neoplasias da Língua
Neoplasias Tonsilares
Neoplasias Urogenitais
Limites: Seres Humanos
Masculino
Feminino
Criança
Responsável: AR16.1 - Biblioteca


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Id: lil-783395
Autor: Mucientes H, Francisco; Yañez Q, Francisco; Zuloaga S, Sergio; Mucientes B, Pablo; Klaassen P, Rodrigo.
Título: Tumor adenomatoide urológico: presentación clínico-patológica de 14 casos / Urologic adenomatoid tumor: clinico pathological presentation of 14 cases
Fonte: Rev. chil. urol;77(2):111-114, 2012. ilus, tab.
Idioma: es.
Resumo: El Tumor Adenomatoide es la neoplasia paratesticular más frecuente y localizada principalmente en el epidídimo. Material y método: Se presenta una serie clínico-patológica de 14 tumores adenomatoides urológicos diagnosticados entre 1975-2011. Resultados: La edad media de presentación fue de 46 años (rango 32-67 años). La mayoría de los casos se presentó como un nódulo firme indoloro en el epidídimo. No hubo casos de localización intratesticular. Se realizó tumorectomía en 13 casos y además orquiectomía en uno. Los tumores midieron una media de 1.9 cm (rango 0.3-5 cm) y macroscópicamente fueron sólidos, blanquecinos y bien delimitados. A la histología estaban formados por estructuras adenomatoides irregulares rodeadas por tejido fibroso. La inmunotinción para Queratina y Calretinina fueron positivas, lo que apoya el origen mesotelial del tumor. El curso clínico fue benigno en todos los casos, sin presentar recurrencias. Conclusión: Corresponde a una neoplasia benigna urogenital rara de origen mesotelial y que compromete con frecuencia el epidídimo. Se presentaron en hombres de edad media y que en la mayoría fueron tratados con tumorectomía, mostrando un curso clínico benigno...

Adenomatoid Tumor is the most frequent paratesticular neoplasia and it is located mainly in the epididymis. Material and methods: A series of 14 cases of Urological Adenomatoid Tumor diagnosed between 1975 - 2011 is presented. Results: Average age at presentation was 46 years (range 32-67 years). The majority of the cases were presented as a painless and firm nodule in the epididymis. No cases involving the testicular parenchyma were seen. The tumors measured an average of 1.9 cm (range 0.3 - 5 cm) and grossly all cases were solid, whitish and fair/y well demarcated. The histology revealed adenomatoid structures surrounded by fibrous tissue. The immunostains were positive for keratin and calretinin which support' the mesothelialial origin of the tumor. All cases showed a benign clinical course and no relapses were found. Conclusion: Correspond to a rare benign urogenital/neoplasia that frequently involves the epidermis. They were presented in middle age men and in the majority of the cases were treated by lumpectomy, showing a bening clinical course...
Descritores: Epididimo/patologia
Neoplasias dos Genitais Masculinos/epidemiologia
Neoplasias dos Genitais Masculinos/patologia
Tumor Adenomatoide/epidemiologia
Tumor Adenomatoide/patologia
Limites: Seres Humanos
Masculino
Adulto
Meia-Idade
Responsável: CL10.1 - Biblioteca Biomédica


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Texto completo SciELO Brasil
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Id: lil-741083
Autor: Lopes Filho, Lauro Lourival; Lopes, Ione Maria Ribeiro Soares; Lopes, Lauro Rodolpho Soares; Enokihara, Milvia M. S. S.; Michalany, Alexandre Osores; Matsunaga, Nobuo.
Título: Mammary and extramammary Paget's disease
Fonte: An. bras. dermatol;90(2):225-231, Mar-Apr/2015. tab, graf.
Idioma: en.
Resumo: Paget's disease, described by Sir James Paget in 1874, is classified as mammary and extramammary. The mammary type is rare and often associated with intraductal cancer (93-100% of cases). It is more prevalent in postmenopausal women and it appears as an eczematoid, erythematous, moist or crusted lesion, with or without fine scaling, infiltration and inversion of the nipple. It must be distinguished from erosive adenomatosis of the nipple, cutaneous extension of breast carcinoma, psoriasis, atopic dermatitis, contact dermatitis, chronic eczema, lactiferous ducts ectasia, Bowen's disease, basal cell carcinoma, melanoma and intraductal papilloma. Diagnosis is histological and prognosis and treatment depend on the type of underlying breast cancer. Extramammary Paget's disease is considered an adenocarcinoma originating from the skin or skin appendages in areas with apocrine glands. The primary location is the vulvar area, followed by the perianal region, scrotum, penis and axillae. It starts as an erythematous plaque of indolent growth, with well-defined edges, fine scaling, excoriations, exulcerations and lichenification. In most cases it is not associated with cancer, although there are publications linking it to tumors of the vulva, vagina, cervix and corpus uteri, bladder, ovary, gallbladder, liver, breast, colon and rectum. Differential diagnoses are candidiasis, psoriasis and chronic lichen simplex. Histopathology confirms the diagnosis. Before treatment begins, associated malignancies should be investigated. Surgical excision and micrographic surgery are the best treatment options, although recurrences are frequent.
Descritores: Neoplasias da Mama/patologia
Doença de Paget Extramamária/patologia
Doença de Paget Mamária/patologia
Neoplasias Cutâneas/patologia
-Neoplasias da Mama/terapia
Carcinoma/patologia
Carcinoma/terapia
Diagnóstico Diferencial
Neoplasias dos Genitais Masculinos/patologia
Neoplasias dos Genitais Masculinos/terapia
Mamilos/patologia
Doença de Paget Extramamária/terapia
Doença de Paget Mamária/terapia
Neoplasias Cutâneas/terapia
Neoplasias Vulvares/patologia
Neoplasias Vulvares/terapia
Limites: Feminino
Seres Humanos
Masculino
Tipo de Publ: Revisão
Responsável: BR1.1 - BIREME


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Id: lil-669926
Autor: Hospital Sírio Libanês.
Título: Manual de oncologia clínica / Manual of Clinical Oncology.
Fonte: Rio de Janeiro; Reichmann e Affonso; 2004. 420 p.
Idioma: pt.
Descritores: Neoplasias da Mama
Neoplasias dos Genitais Femininos
Neoplasias dos Genitais Masculinos
Neoplasias de Cabeça e Pescoço
Oncologia
Limites: Seres Humanos
Responsável: BR75.1 - Biblioteca
BR75.1; 616-006.6, H794m. 1626


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Id: lil-661905
Autor: Avilán Rovira, J. M.
Título: Distribución nacional del virus del papiloma humano / National distribution of the human papiloma virus
Fonte: Gac. méd. Caracas;120(4):271-272, oct.-dic. 2012.
Idioma: es.
Descritores: Infecções por Papillomavirus/etnologia
Neoplasias do Colo do Útero/etnologia
Neoplasias Penianas/etnologia
Papiloma/complicações
Papiloma/diagnóstico
-Neoplasias dos Genitais Femininos
Neoplasias dos Genitais Masculinos
Limites: Seres Humanos
Masculino
Feminino
Tipo de Publ: Editorial
Responsável: VE1.1 - Biblioteca Humberto Garcia Arocha


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Texto completo SciELO Brasil
Alvarenga, Marcelo
Texto completo
Id: lil-614940
Autor: Alvarenga, César Augusto; Lopes, José Manuel; Vinagre, João; Paravidino, Paula Itagyba; Alvarenga, Marcelo; Prando, Adilson; Castilho, Lísias Nogueira; Soares, Paula; Billis, Athanase.
Título: Paraganglioma of seminal vesicle and chromophobe renal cell carcinoma: a case report and literature review / Paraganglioma da vesícula seminal e carcinoma de células renais cromófobo: um relato de caso e revisão da literatura
Fonte: Säo Paulo med. j;130(1):57-60, 2012. ilus, tab.
Idioma: en.
Resumo: CONTEXT: Extra-adrenal paragangliomas are rare tumors that have been reported in many locations, including the kidney, urethra, urinary bladder, prostate, spermatic cord, gallbladder, uterus and vagina. CASE REPORT: This report describes, for the first time to the best of our knowledge, a primary paraganglioma of the seminal vesicle occurring in a 61-year-old male. The patient presented persistent arterial hypertension and a previous diagnosis of chromophobe renal cell carcinoma. It was hypothesized that the seminal vesicle tumor could be a metastasis from the chromophobe renal cell carcinoma. Immunohistochemical characterization revealed expression of synaptophysin and chromogranin in tumor cell nests and peripheral S100 protein expression in sustentacular cells. Succinate dehydrogenase A and B-related (SDHA and SDHB) expression was present in both tumors. CONCLUSIONS: No genetic alterations to the VHL and SDHB genes were detected in either the tumor tissue or tissues adjacent to the tumor, which led us to rule out a hereditary syndrome that could explain the association between paraganglioma and chromophobe renal cell carcinoma in a patient with arterial hypertension.

CONTEXTO: Paragangliomas extra-adrenais são tumores raros que têm sido relatados em muitas localizações, incluindo rim, uretra, bexiga, próstata, cordão espermático, vesícula biliar, útero e vagina. RELATO DE CASO: Este relato descreve, pela primeira vez em nosso conhecimento, um paraganglioma primário da vesícula seminal ocorrendo em um paciente do sexo masculino de 61 anos de idade. O paciente apresentou hipertensão arterial persistente e um diagnóstico prévio de carcinoma de células renais cromófobo (CCRC). Foi pensado que o tumor de vesícula seminal poderia ser uma metástase do CCRC. A caracterização imunoistoquímica revelou expressão de sinaptofisina e cromogranina nos ninhos de células tumorais e expressão de proteína S100 nas células sustentaculares. Expressão de succinato de-hidrogenase A e B relacionada (SDHA e SDHB) estiveram presentes em ambos os tumores CONCLUSÕES: Nenhuma alteração genética dos genes VHL e SDHB foi detectada nos tecidos tumorais e adjacentes ao tumor, o que nos levou a afastar uma síndrome hereditária que poderia explicar a associação entre o paraganglioma e o CCRC em um paciente com hipertensão arterial.
Descritores: Carcinoma de Células Renais/patologia
Neoplasias dos Genitais Masculinos/patologia
Neoplasias Renais/patologia
Neoplasias Primárias Múltiplas/patologia
Paraganglioma/patologia
Glândulas Seminais/patologia
-Diagnóstico Diferencial
Neoplasias dos Genitais Masculinos/genética
Hipertensão/etiologia
Neoplasias Primárias Múltiplas/genética
Paraganglioma/genética
Succinato Desidrogenase/genética
Proteína Supressora de Tumor Von Hippel-Lindau/genética
Limites: Seres Humanos
Masculino
Meia-Idade
Tipo de Publ: Relatos de Casos
Research Support, Non-U.S. Gov't
Revisão
Responsável: BR1.1 - BIREME


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Id: lil-571150
Autor: Canedo-Patzi, Ana Marcela; León-Bojorge, Beatriz de; Ortíz-Hidalgo, Carlos.
Título: Tumor adenomatoide del aparato genital: estudio clinicopatológico e inmunohistoquímico de 9 casos / Adenomatoid tumor of the genital tract: clinical, pathological and immunohistochemical study in 9 cases
Fonte: Gac. méd. Méx;142(1):59-66, ene.-feb. 2006. tab, ilus.
Idioma: es.
Resumo: Objetivo: Estudio clinico-patológico e inmunohistoquímico de tumores adenomatoides del aparato genital. Material y métodos: Se describen las características histológicas e inmunohistoquímicas de nueve tumores adenomatoides del Centro Médico ABC diagnosticados entre enero del 2000 a mayo del 2004. Resultados: Ocho mujeres y un hombre. Las edades variaron entre 28 y 54 años de edad. Los tumores se localizaron en útero (siete), salpinge (uno) y epidídimo (uno). El tamaño de los tumores varió entre 0.4 y 5.8cm. Se encontraron tres patrones histológicos: adenoide, angiomatoide y sólido. Características histológicas peculiares fueron la disposición de los túbulos neoplásicos alrededor de los fascículos de músculo liso y la localización periférica del patrón angiomatoide y central de los patrones sólido y adenoide en el tumor. Inmunohistoquímicamente todos los tumores mostraron positividad intensa y difusa para calretinina y AE1/AE3. La trombomodulina fue positiva en todos los tumores (focal y débil en el patrón angiomatoide y difusa e intensa en los patrones adenoide y sólido). La CK5/6 fue positiva en siete tumores (difusa en tres y focal en cuatro). Dos tumores fueron negativos para este marcador. Todos los tumores fueron negativos para CD31. Conclusiones: El inmunofenotipo expresado en nuestros casos confirma el origen mesotelial de los tumores adenomatoides.

OBJECTIVE: Describe the histological and immunohistochemical features of nine genital tract adenomatoid tumors. MATERIAL AND METHODS: Nine cases of adenomatoid tumors were collected from the files of the Pathology department at a private hospital (ABC Hospital). Tumors were studied from a histological and inmunohistochemical perspective. RESULTS: Eight women and one man were studied. Age range was 28-54 yrs. Tumors were located in the uterus (seven),fallopian tube (one) and epididymis (one). Tumor size ranged from 0.4 to 5.8 cm. We observed three histological patterns: adenoid, angiomatoid and solid. Arrangement of the neoplastic tubules around fascicles of smooth muscle; angiomatoidpattern with a peripheral location, and solid and adenoidpatterns with a central location in the tumor were some of the observed histological features. Immunohistochemically all tumors exhibited strong and diffuse positivity for calretinin and AE1/AE3. Thrombomodulin was positive in all tumors (focal and weak in angiomatoid pattern and diffuse and strong in adenoid and solid patterns). The CK5/6 antibody was positive in seven tumors (diffuse in three and focal in four). Two tumors were negative for this marker. All tumors were negative for CD31. CONCLUSIONS: The immunopheno type of the adenomatoid tumors in our series confirms their mesothelial origin.
Descritores: Epididimo
Neoplasias Uterinas/patologia
Neoplasias das Tubas Uterinas/patologia
Neoplasias dos Genitais Masculinos/patologia
Tumor Adenomatoide/patologia
-Imuno-Histoquímica
Limites: Seres Humanos
Masculino
Feminino
Adulto
Meia-Idade
Responsável: BR1.1 - BIREME


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Id: lil-549128
Autor: Vidal-Mora, Ivar; Castillo, Octavio.
Título: Metástasis peneana y escrotal por cáncer de próstata / Prostatic cancer metastasis to the penis and scrotum
Fonte: Rev. chil. urol;73(3):243-243, 2008. ilus.
Idioma: es.
Descritores: Neoplasias da Próstata/patologia
Neoplasias dos Genitais Masculinos/secundário
Neoplasias Penianas/secundário
-Escroto
Limites: Seres Humanos
Masculino
Meia-Idade
Tipo de Publ: Relatos de Casos
Responsável: CL10.1 - Biblioteca Biomédica



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