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Id: lil-497164
Autor: Pereira, Gustavo M; Lira, Patricia.
Título: Ictericia obstructiva / Obstructive Jaundice
Fonte: Med. infant;14(4):303-308, dic. 2007. ilus.
Idioma: es.
Descritores: Ultrassonografia
Cirrose Hepática Biliar/diagnóstico
Hepatopatias/diagnóstico
Icterícia Obstrutiva
Neoplasias de Tecido Muscular/diagnóstico
Neoplasias de Tecido Muscular/terapia
Omento
Limites: Criança
Tipo de Publ: Relatos de Casos
Responsável: AR94.1 - Centro de Información Pediatrica


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Id: biblio-1092966
Autor: Toro, Luis Guillermo; Correa, Elizabeth María; Calle, Luisa Fernanda; Ocampo, Adriana; Vélez, Sandra María.
Título: Enfermedades hepáticas y embarazo / Liver diseases and pregnancy
Fonte: Rev. colomb. gastroenterol;34(4):385-398, oct.-dic. 2019. tab.
Idioma: es.
Resumo: Resumen La prevalencia de las enfermedades hepáticas en el embarazo no es despreciable, ya que estas se presentan en 3%-5% de todas las gestaciones. Entre las múltiples causas se encuentran cambios fisiológicos del embarazo; enfermedad hepática preexistente, siendo las más comunes las enfermedades colestásicas (colangitis biliar primaria y colangitis esclerosante primaria), hepatitis autoinmune, enfermedad de Wilson, hepatitis virales crónicas, cirrosis establecida de cualquier etiología y paciente con historia de trasplante hepático; enfermedad hepática adquirida durante el embarazo, siendo las principales las hepatitis virales, la toxicidad inducida por medicamentos y la hepatolitiasis; hepatopatía relacionada con el embarazo, en la cual se encuentran 5 entidades principales: hiperémesis gravídica, colestasis intrahepática del embarazo, preeclampsia, síndrome HELLP e hígado graso del embarazo. La severidad de estas entidades tiene una amplia gama de presentaciones, desde la paciente que es completamente asintomática, hasta la falla hepática aguda e incluso la muerte. La gravedad del cuadro se asocia con una morbilidad y mortalidad significativas tanto para la madre como para el feto, lo cual hace que una evaluación rápida, diagnóstico certero y manejo apropiado por un equipo multidisciplinario (incluida obstetricia de alto riesgo, hepatología, gastroenterología y radiología intervencionista), en un servicio que tenga la posibilidad de ofrecer trasplante hepático, sean fundamentales para obtener buenos desenlaces.

Abstract Liver diseases develop in 3% to 5% of all gestations. Among the causes are: 1. Physiological changes of pregnancy. 2. Pre-existing liver diseases and conditions. The most common are cholestatic diseases such as primary biliary cholangitis and primary sclerosing cholangitis. Others include autoimmune hepatitis, Wilson's disease, chronic viral hepatitis, cirrhosis of any etiology and histories of liver transplantation. 3. Liver disease acquired during pregnancy, especially viral hepatitis, drug-induced toxicity and hepatolithiasis. 4. Pregnancy-related liver diseases including hyperemesis gravidarum, intrahepatic cholestasis of pregnancy, preeclampsia, HELLP syndrome and fatty liver of pregnancy. Severity ranges from absence of symptoms to acute liver failure and even death. Severe cases have significant morbidity and mortality for both mother and fetus. These cases require rapid evaluation, accurate diagnosis and appropriate management by a multidisciplinary team including high-risk obstetrics, hepatology, gastroenterology and interventional radiology. Availability of liver transplantation is also important for obtaining good outcomes.
Descritores: Pré-Eclâmpsia
Gravidez
Transplante de Fígado
Hepatite
Hiperêmese Gravídica
Cirrose Hepática Biliar
Limites: Humanos
Feminino
Gravidez
Tipo de Publ: Revisão
Responsável: CO354 - Sociedad Colombiana de Gastroenterología


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Id: biblio-1157400
Autor: Sánchez Adriana; Hernández Nelia; Chiodi Daniela; Berrueta Joaquín; Robaina Gabriela; Pollio Carmen; Mescia Germán.
Título: Cirrosis biliar primaria: aspectos clinico- epidemiológicos en una población uruguaya / [Primary biliary cirrhosis: clinical and epidemiological features in an Uruguayan population].
Fonte: Acta gastroenterol. latinoam;43(4):288-93, 2013 Dec.
Idioma: es.
Resumo: INTRODUCTION: Primary biliary cirrhosis (PBC) is a chronic cholestatic, autoimmune, liver disease produced by inflammation and destruction of the interlobular bile ducts. It is more frequent among female patients and is usually diagnosed in the fifth decade of life. OBJECTIVE: Our objective was to describe the clinical and epidemiological characteristics of patients with PBC in Uruguay. MATERIAL AND METHODS: This descriptive study included patients from 3 medical centers diagnosed with PBC in the period January 2002 to September 2011. The diagnosis was based on the presence of at least two of the following requirements: cholestasis, antimitochondrial antibodies (AMA) (or AMA subtype 2) or positive antinuclear antibodies (ANA) (anticentromere pattern) and compatible biopsy. Data recorded were sex, age, symptoms, related illness, laboratory results, images and histology at the moment of the diagnosis. RESULTS: We included 81 patients, 94

were women and the mean age was 56 years old (range: 31 to 79 years old). Symptoms were present in 59 patients (73

) and pruritus, found in 51 of them (86

), was the most frequent symptom. Positive AMA was found in 84

of cases. Histological study was available in 35 patients (43

) and 13 of them (37

) had cirrhosis. The mean survival according to the presence or absence of cirrhosis was 9.17 years (95

confidence interval: 6.79-11.56) and 10.7 years (95

confidence interval: 9.27-12.14), respectively (P = 0.03). CONCLUSIONS: Female predominance and frequent association with other autoimmune diseases were confirmed in this group. Although there was a high percentage of symptomatic and cirrhotic patients at diagnosis, only the presence of cirrhosis was associated with a lower survival.
Descritores: Cirrose Hepática Biliar
-Adulto
Anticorpos Antinucleares/sangue
Autoanticorpos/sangue
Biópsia
Cirrose Hepática Biliar/diagnóstico
Cirrose Hepática Biliar/mortalidade
Cirrose Hepática Biliar/sangue
Estimativa de Kaplan-Meier
Estudos Retrospectivos
Estudos de Coortes
Feminino
Humanos
Idoso
Masculino
Mitocôndrias/imunologia
Pessoa de Meia-Idade
Uruguai/epidemiologia
Índice de Gravidade de Doença
Tipo de Publ: Resumo em Inglês
Artigo de Revista
Responsável: AR5.1 - Centro de Gestión del Conocimiento y las Comunicaciónes


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Texto completo SciELO Cuba
Texto completo
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Id: biblio-1149922
Autor: Villamil Martínez, Ramón; Pi Osoria, Andrés José; Ramírez Guirado, Alejandro; Pérez Duvergel, Anecio; Betancourt Berriz, Daniela; Silverio García, César; Cobas Torres, Yanisleidys.
Título: Guía de práctica clínica en atresia de las vías biliares / Clinical practice guidelines in biliary atresia
Fonte: Rev. cuba. pediatr;92(4):e1168, oct.-dic. 2020.
Idioma: es.
Resumo: Basada en la mejor evidencia científica disponible, se presenta la guía de práctica clínica en atresia de vías biliares, la cual se define como una obstrucción progresiva de las vías biliares intra- o extrahepáticas en recién nacidos y lactantes pequeños y causa ictericia colestásica grave y cirrosis hepática. Es una enfermedad poco frecuente, de etiología desconocida, con mayor incidencia en países asiáticos. Clínicamente se expresa por ictericia obstructiva, acolia, coluria y hepatoesplenomegalia. Los complementarios expresan una hiperbilirrubinemia directa con aumento de las enzimas hepáticas, y el diagnóstico se confirma en nuestro hospital con la colangiografía, generalmente en el curso de una laparoscopía. El tratamiento es quirúrgico y consiste en la portoenterostomía de Kasai, con mejores resultados en cuanto al drenaje biliar si se realiza antes de los 60 días de vida, así como el trasplante hepático. La enfermedad tiene un curso progresivo hacia la cirrosis hepática en etapas tempranas de la vida, sobre todo si no se realiza el diagnóstico y tratamiento quirúrgico precozmente, con implicaciones en la supervivencia y calidad de vida de estos pacientes. Por tanto, referir precozmente al paciente con sospecha de atresia de vías biliares a un centro especializado es la piedra angular de la actitud médica. La presente guía de práctica clínica pretende ofrecer las herramientas técnicas estandarizadas para mejorar los resultados a los pacientes con esta enfermedad, así como contribuir con la docencia y las investigaciones(AU)

Based on the best scientific evidence available, it is presented the clinical practice guidelines on biliary atresia. This disease is defined as a progressive obstruction of the intra and/or extrahepatic bile ducts in newborns and young infants, causing severe cholestatic jaundice and cirrhosis of the liver. It is a rare disease of unknown etiology, with a higher incidence in Asian countries. It is clinically expressed by obstructive jaundice, acholia, choluria and hepatosplenomegaly. Laboratory tests show a direct hyperbilirubin and elevated liver enzymes, and in our hospital, the diagnosis is confirmed by a cholangiography, usually during a laparoscopy procedure. It has surgical treatment and it involves a Kasai portoenterostomy, with better results regarding biliary drainage if it is performed before 60 days of life, as well as liver transplant. This condition has a progressive course towards liver cirrhosis in early stages of life, mainly if the diagnosis and surgical treatment are not made timely, with implications for the survival and quality of life of these patients. Therefore, early referral of the patient with suspected biliary atresia to a specialized center is the cornerstone of the medical attitude. This clinical practice guidelines aims to offer standardized technical tools to improve the outcome for patients with this disease, as well as to contribute to teaching and research(AU)
Descritores: Atresia Biliar/cirurgia
Atresia Biliar/epidemiologia
Icterícia Obstrutiva/complicações
Cirrose Hepática Biliar/complicações
Limites: Humanos
Masculino
Feminino
Recém-Nascido
Lactente
Tipo de Publ: Guia de Prática Clínica
Responsável: CU1.1 - Biblioteca Médica Nacional


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Id: biblio-887255
Autor: Melchor-Mendoza, Yazmin Karel; Martínez-Benítez, Braulio; Mina-Hawat, Aline; Rodríguez-Lea, Gustavo; Duque, Ximena; Morán-Villota, Segundo.
Título: Ursodeoxycholic Acid Therapy in Patients with Primary Biliary Cholangitis with Limited Liver Transplantation Availability
Fonte: Ann. hepatol;16(3):430-435, May.-Jun. 2017. tab, graf.
Idioma: en.
Resumo: ABSTRACT Introduction. There is little information on survival rates of patients with primary biliary cholangtis (PBC) in developing countries. This is particularly true in Latin America, where the number of liver transplants performed remains extremely low for patients with advanced liver disease who fulfill criteria for liver transplantation. The goal of this study was to compare survival rate of patients with PBC in developing countries who were treated with ursodeoxycholic acid (UDCA) versus survival of patients who received other treatments (OT) without UDCA, prescribed before the UDCA era. Material and methods. A retrospective study was performed, including records of 78 patients with PBC in the liver unit in a third level referral hospital in Mexico City. Patients were followed for five years from initial diagnosis until death related to liver disease or to the end of the study. Patients received UDCA (15 mg/kg/per day) (n = 41) or OT (n = 37) before introduction of UDCA in Mexico. Results. Response to treatment was higher in the group that received UDCA. In the five years of follow-up, survival rates were significantly higher in the UDCA group than in the OT group. The hazard ratio of death was higher in the OT group vs. UDCA group, HR 8.78 (95% Cl, 2.52-30.61); Mayo Risk Score and gender were independently associated with the risk of death. Conclusions. The study confirms that the use of UDCA in countries with a limited liver transplant program increases survival in comparison to other treatments used before the introduction of UDCA.(AU)
Descritores: Ácido Ursodesoxicólico/uso terapêutico
Transplante de Fígado/efeitos adversos
Cirrose Hepática Biliar/fisiopatologia
-Taxa de Sobrevida
Estudos Retrospectivos
América Latina
Limites: Humanos
Responsável: BR1.1 - BIREME


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Id: biblio-1000268
Autor: González Castillo, Daniel David; Castillo Ortíz, Diana Cristina; Villacís Vaca, Verónica del Pilar; Villacís Tamayo, Rómulo Abad.
Título: Síndrome de Reynolds en Hospital Carlos Andrade Marín, serie de casos y revisión / Reynolds Syndrome in Carlos Andrade Marin Hospital: a series of cases and review
Fonte: Cambios rev. méd;15(2):47-50, jul. 2016. ilus, tab.
Idioma: es.
Resumo: Introducción: El Síndrome de Reynolds es la asociación de esclerosis sistémica (SSC) con cirrosis biliar primaria (CBP). Descrito en 1934 por Milbradt y Reynolds en 1976 describió seis casos. Caso: Presentamos tres casos de mujeres atendidas en el Servicio de Reumatologìa del Hospital Carlos Andrade Marín, con patología hepática autoinmune y signos de esclerosis sistémica. El diagnóstico fue confirmado mediante biopsia hepática en dos de ellas y la prueba de fibromax en la restante. Discusión: Reconocer el Síndrome de Reynolds permite el diagnóstico temprano de cirrosis biliar primaria en pacientes con esclerosis sistémica y sospechar esta entidad en quienes padecen enfermedad hepática colestásica autoinmune que, muchas veces, coexisten en forma silenciosa. El diagnóstico oportuno permite intervenciones terapéuticas precoces que podrían mejorar el pronóstico de esta asociación.

Introduction: The Reynolds' syndrome is the combination of systemic sclerosis (SSC) and primary biliary cirrhosis (PBC). It was first described in 1934 by Milbradt. Reynolds in 1976 presented six cases in two of them and fibromax-test in another. Case report: We present three cases of three women treated in the Rheumatology department at Carlos Andrade Marin hosppital who had autoinmune liver disease confirmed by biopsy. Discusion: Recognizing Reynolds' Syndrome allow us to make earlier diagnosis. This autoimmune cholestatic liver disease often remains silent, so that their identification is a valuable diagnostic tool leading to therapeutic interventions.
Descritores: Reumatologia
Escleroderma Sistêmico
Número de Reynolds
Diagnóstico
Cirrose Hepática Biliar
-Prognóstico
Mulheres
Pessoa de Meia-Idade
Limites: Humanos
Feminino
Idoso de 80 Anos ou mais
Tipo de Publ: Relatos de Casos
Responsável: EC162.1


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Amorim, Americo Gusmao
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Id: biblio-876775
Autor: Fonseca Neto, Olival Cirilo Lucena da; Lopes, Vladmir Goldstein de Paula; Rabello, Priscylla; Melo, Paulo Sergio Vieira de; Amorim, Américo Gusmão; Lacerda, Cláudio Moura.
Título: Transplante hepático no tratamento de lesão iatrogênica de via biliar após colecistectomia: um estudo em centro de referência no Nordeste do Brasil / Liver transplantation for treatment of biliary iatrogenic injury after cholecistectomy: a study in reference center in the Northeast of Brazil
Fonte: GED gastroenterol. endosc. dig;36(3):77-82, Jul.-Set. 2017. ilus, tab.
Idioma: pt.
Resumo: Introdução: a lesão iatrogênica de via biliar é uma grave complicação cirúrgica que pode ocorrer durante a realização de colecistectomia. Os pacientes portadores desse tipo de lesão podem evoluir com cirrose biliar secundária a despeito de múltiplos tratamentos cirúrgicos, sendo necessário o transplante hepático como a última opção para tratamento. Objetivo: analisar o perfil dos pacientes em um centro de referência no Nordeste do Brasil submetidos a transplante hepático por lesão iatrogênica de via biliar. Métodos: foram analisados retrospectivamente 730 prontuários na Unidade de Transplante de Fígado do Hospital Universitário Oswaldo Cruz, no período de 2001 até 2015, e selecionados os oito pacientes submetidos a transplante hepático por lesão iatrogênica de via biliar. Resultados: a idade variou entre 26 e 61 anos, sendo seis indivíduos do sexo feminino. A cirurgia inicial foi a colecistectomia aberta em sete casos e videolaparoscópia em um caso. Em uma oportunidade, a lesão foi identificada durante a colecistectomia. Os sintomas se assemelharam com os descritos na literatura, incluindo colangite de repetição. Quatro pacientes eram portadores de lesão E2 e três de lesão tipo E3 de Strasberg. Seis pacientes já haviam sido submetidos a abordagens cirúrgicas prévias e o tempo entre a lesão inicial e o transplante variou entre três (3) e vinte e seis anos (26). Todos os pacientes eram portadores de Cirrose Biliar Secundária e o tempo na lista de espera para transplante variou entre 111 e 1123 dias. O MELD teve uma média de 16. O transplante foi realizado por técnica convencional em seis casos e Piggyback em dois, sendo a reconstrução por hepaticojejunostomia realizada em todos. Um paciente necessitou de retransplante, evoluindo a óbito. Conclusão: transplante hepático por lesão iatrogênica de via biliar é mais comum naqueles pacientes que demoraram a ser encaminhados para centro de referência e que foram submetidos a múltiplos procedimentos prévios.

Background: iatrogenic bile duct injury is a serious surgical complication that may occur during cholecystectomy.Patients with this type of lesion may develop secondary biliary cirrhosis, despite multiple surgical treatments, requiring liver transplantation as the last measure. Aim: analyze the patients submitted to hepatic transplantation due to iatrogenic bile duct injury in a referral center in the Northeast of Brazil. Results: the age ranged from 26 to 61 years, with six females. The initial surgery was open cholecystectomy in seven cases and videolaparoscopic in one case. In one patient the lesion was identified during cholecystectomy. The symptoms resembled those described in the literature, including recurrent cholangitis. Four patients had E2 lesions and three E3 lesions from Strasberg. Six patients had undergone previous surgical approaches and the time between initial injury and transplantation ranged from three to twenty-six years. All patients had secondary Biliary Cirrhosis and the time on the transplant waiting list varied between 111 and 1123 days. The MELD had an average of 16. The transplantation was performed by conventional technique in six cases and Piggyback in two, and reconstruction by hepaticojejunostomy performed in all. One patient needed a re-transplant and the same patient died one year later. Conclusion: hepatic transplantation due to iatrogenic bile duct injury is more common in those patients who were delayed to be referred to a referral center and who underwent multiple previous surgical procedures.
Descritores: Ductos Biliares
Colecistectomia
Colecistectomia/efeitos adversos
Transplante de Fígado
Colecistectomia Laparoscópica
Doença Iatrogênica
Cirrose Hepática Biliar
-Registros Médicos
Estudos Retrospectivos
Limites: Humanos
Masculino
Feminino
Adulto
Pessoa de Meia-Idade
Responsável: BR9.1 - Biblioteca de Ciências da Saúde Profa. Susana Schimidt


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Id: biblio-1102342
Autor: Montenegro-­Polo, Merly.
Título: Esclerodermia y Cirrosis Biliar Primaria (Síndrome de Reynolds): Descripción de un Caso / Scleroderma and Primary Biliary Cirrhosis (Reynolds syndrome): Case Description
Fonte: Rev. méd. Panamá;39(1):25-27, 2019.
Idioma: es.
Resumo: El síndrome de Reynolds, se define como cirrosis biliar primaria en pacientes con esclerodermia; este síndrome debe ser sospechado en aquellos pacientes que desarrollen un patrón colestásico. Se reporta una paciente con antecedente de esclerodermia que se presenta con ictericia, a quien se le confirma con estudios inmunológicos y biopsia hepática, el diagnóstico de cirrosis biliar prima­ ria (ahora se denomina colangitis biliar primaria). Se ordena ácido ursodesoxicólico 15mg/día.

Reynolds syndrome is defined as primary biliary cirrhosis in patients with scleroderma; this syndro­me should be suspected in those patients who develop a cholesteric pattern. We report a patient with scleroderma who presented with jaundice. After immunological and liver biopsy, a diagnosis of Primary Biliary Cholangiopathy (new name) was confirmed. Ursodeoxycholic acid 15mg / day was prescribed
Descritores: Escleroderma Sistêmico
Cirrose Hepática Biliar/patologia
-Ácido Ursodesoxicólico/farmacocinética
Fígado/patologia
Limites: Humanos
Feminino
Pessoa de Meia-Idade
Tipo de Publ: Relatos de Casos
Responsável: PA30.1 - BINASA - Biblioteca Nacional de Salud


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Id: biblio-1103903
Autor: Arcos M, Mario; Ruiz F, Marco; Fuentes-López, Eduardo; Álvarez G, Daniel; Duarte G. de C, Ignacio; Arrese J, Marco; Riquelme P, Arnoldo; Soza R, Alejandro.
Título: Chlamydophila pneumoniae infection is not associated with primary biliary cholangitis / La infección por Chlamydophila pneumoniae no está asociada con colangitis biliar primaria
Fonte: Gastroenterol. latinoam;30(2):58-63, 2019. tab.
Idioma: en.
Resumo: ANTECEDENTES: La colangitis biliar primaria (CBP) es una enfermedad hepática inflamatoria crónica colestásica de causa desconocida. Varios patógenos virales y bacterianos han sido propuestos como factores que podrían gatillar una respuesta inmune por mimetismo molecular, o directamente estar relacionados en la persistencia del daño biliar. Existen reportes controversiales respecto al rol de en la patogenia de CBP. OBJETIVOS: Investigar marcadores de infección de séricos y en hígado de pacientes con CBP. PACIENTES Y MÉTODOS: Veinte pacientes diagnosticados con CBP y 20 pacientes control con otras enfermedades hepáticas crónicas no colestásicas fueron estudiados. Se determinaron anticuerpos séricos anti- (IgG). Se realizó detección inmunohistoquímica de antígenos de en hígado. Se extrajo DNA de hígado para amplificación de la secuencia específica de rRNA 16S de por PCR. Fueron usados controles de amplificación de DNA bacteriano y humano. Los pacientes firmaron consentimiento informado. Se realizó un metaanálisis de la diferencia de riesgo de CBP en pacientes infectados por y en un grupo control. RESULTADOS: Los anticuerpos séricos fueron positivos en 30% de los pacientes con CBP y 50% de los controles (p = NS). Antígenos de no fueron detectados en tejido hepático de pacientes con CBP ni de controles. No se amplificó ADN bacteriano en ninguna de las muestras. El metaanálisis de la diferencia de riesgo mostró gran heterogeneidad de los estudios, por lo que no se realizó una estimación de diferencia de riesgo agrupada. DISCUSIÓN: No encontramos asociación entre infección por y CBP. En la evidencia actual, un estudio presenta resultados a favor de la asociación entre y CBP y tres estudios resultados en contra.,

Primary biliary cholangitis (PBC) is a chronic cholestatic inflammatory liver disease of unknown cause. Several viral and bacterial pathogens have been proposed as factors that could either trigger an immune response by molecular mimicry or directly be involved in the persistence of biliary damage. There are conflicting reports respecting the role of in the pathogenesis of PBC. To investigate markers of infection in serum and liver tissue from patients with PBC. Twenty patients with diagnosis of PBC and 20 control patients with other non-cholestatic chronic liver diseases were studied. Serum anti- antibodies (IgG) were determined. Liver tissue was available for immunohistochemistry detection of antigens. DNA was extracted from liver tissue and a specific sequence of 16S rRNA gene was amplified by CPR. Adequate controls of bacterial and human DNA amplification were used. Informed consent was obtained from patients. A meta-analysis of risk difference of PBC in Chlamydophila pneumoniae infected patients and in the control groupwas performed. Serum antibodies were positive in 30% of patients with PBC and 50% of controls (p = NS). antigens were not detected in liver tissue neither of patients with PBC nor controls. Bacterial DNA did not amplify in any of the samples, despite good amplification of internal and external controls. Risk difference meta-analysis showed high heterogeneity between studies. Therefore, we did not estimate a pooled risk difference. Our results do not support the association between infection and PBC. In the current literature only one study shows an association between and PBC, but other three studies do not support it.
Descritores: Infecções por Chlamydia/diagnóstico
Infecções por Chlamydophila/complicações
Cirrose Hepática Biliar/diagnóstico
Cirrose Hepática Biliar/microbiologia
-DNA Bacteriano
Imunoglobulina G
Imuno-Histoquímica
RNA Ribossômico 16S/análise
Estudos de Casos e Controles
Reação em Cadeia da Polimerase
Chlamydophila pneumoniae/genética
Fígado/microbiologia
Cirrose Hepática Biliar/etiologia
Limites: Humanos
Masculino
Feminino
Adolescente
Adulto
Pessoa de Meia-Idade
Idoso
Responsável: CL61.1 - Biblioteca Central Campus Sur


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Id: lil-224932
Autor: Loja Orpeza, David; Vilca Vásquez, Maricela; Aviles Gonzaga, Roberto.
Título: Hepatitis autoinmune / Autoinmune hepatitis
Fonte: Rev. méd. hered;8(3):122-5, set. 1997.
Idioma: es.
Resumo: Three patients with autoinmune hepatitis type 1 diagnosed at the Hospital Nacional Arzobispo Loayza in Lima-Per, between 1993 and 1995, are here reported, emphasis is made on the clinical, histological and therapeutical aspects.
Descritores: Colangite Esclerosante
Hepatite Autoimune
Cirrose Hepática Biliar
Hepatite Crônica
Fígado
Tipo de Publ: Relatos de Casos
Responsável: PE1.1 - Oficina Universitária de Biblioteca



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