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Id: lil-628242
Autor: Cabrera Gámez, Maité; Santana Pérez, Felipe; Morales Pérez, Luís Miguel.
Título: Algunas consideraciones de la disfunción endotelial en pacientes con hiperprolactinemia / Some considerations of endothelial dysfunction in patients presenting with hyperprolactinemia
Fonte: Rev. cuba. endocrinol;23(1):106-112, ene.-abr. 2012.
Idioma: es.
Resumo: Se realizó una revisión de las publicaciones a nuestro alcance de la actualidad sobre el tema disfunción endotelial en pacientes con hiperprolactinemia: existencia, mecanismos de producción y consecuencias. Teniendo en cuenta que la hiperprolactinemia tiene hoy un nuevo enfoque relacionado con la disfunción endotelial, nos propusimos realizar la revisión siguiente. La disfunción endotelial es una alteración en la relajación vascular inducida por la reducción de los factores de relajación derivados del endotelio, principalmente el óxido nítrico, que causa un aumento del estímulo vasoconstrictor con tendencia protrombótica de la vasculatura. La resistencia a la insulina actúa como principal factor de disfunción endotelial asociado o no con la diabetes mellitus. Hasta el presente, el estado hiperprolactinémico se asocia con trastornos de la tolerancia a la glucosa (tolerancia a la glucosa disminuida con hiperinsulinemia). Existe disfunción endotelial en mujeres hiperprolactinémicas y puede deberse a su relación con resistencia a la insulina, a la disminución de los estrógenos y a la propia hiperprolactinemia. También se han encontrado marcadores de inflamación (como la proteína C reactiva) elevada en pacientes con esta enfermedad. La hiperprolactinemia se asocia con resistencia a la insulina, disfunción endotelial y bajo grado de inflamación, parámetros que son determinantes en el proceso de aterosclerosis, por lo que esta enfermedad puede ser un factor predisponente de aterosclerosis, y por tanto, un riesgo de morbilidad y mortalidad cardiovasculares(AU)

A review of the publications available of current situation on the subject related to endothelial dysfunction in patients with hyperprolactinemia: existence, production mechanisms and consequences. Taking into account that the hyperprolactinemia has a new approach related to endothelial dysfunction authors made present review. Above mentioned dysfunction is a alteration in the vascular relaxation provoked by decrease of relaxation factors derived from endothelium, mainly the nitric oxide, which cause an increase of vasoconstrictor stimulus with a pro-thrombotic trend of vasculature. The insulin resistance acts as a major factor of endothelial dysfunction associated or not with diabetes mellitus. Until now, the hyperprolactinemia status is associated with disorders of the glucose tolerance (decreased glucose tolerance with hyper-insulinemia). There is endothelial dysfunction in women with hyperprolactinemia and may be due to its relation to insulin resistance, to decrease of estrogens and to the own hyperprolactinemia. Also, there are inflammation's markers (the C-reactive protein) high in patients with this disease. The hyperprolactinemia is associated with the insulin resistance, the endothelial dysfunction and the low degree of inflammation, parameters determinant in the atherosclerosis process, thus, this disease may be a predisposing factor of the atherosclerosis becomes risk of cardiovascular morbidity and mortality(AU)
Descritores: Hiperprolactinemia/fisiopatologia
Endotélio Vascular/fisiologia
-Resistência à Insulina/fisiologia
Literatura de Revisão como Assunto
Aterosclerose/etiologia
Limites: Seres Humanos
Feminino
Responsável: CU1.1 - Biblioteca Médica Nacional


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Id: biblio-984527
Autor: Burlá, Marcelo; Cunha, Ana Rosa; Gismondi, Ronaldo; Oigman, Wille; Neves, Mario Fritsch; Medeiros, Fernanda.
Título: Endothelial Dysfunction and Pulse Wave Reflection in Women with Polycystic Ovarian Syndrome
Fonte: Int. j. cardiovasc. sci. (Impr.);32(1):3-9, jan.-fev. 2019. tab, graf.
Idioma: en.
Resumo: Patients with polycystic ovarian syndrome (PCOS) have an increased prevalence of metabolic syndrome and traditional atherosclerotic risk factors, such as dyslipidemia, diabetes and hypertension. Endothelial function and vascular stiffness are surrogate markers of early atherosclerosis, able to predict cardiovascular events. Objective: To compare endothelial function and pulse wave reflection between women with PCOS and healthy controls. Methods: Observational and cross-sectional study that included women with PCOS, age between 18 and 40 years-old and body mass index between 25.0 and 35.0 kg/m2, and healthy controls. Rotterdan criteria was used to diagnose PCOS. Subjects underwent clinical and anthropometric evaluation, laboratory and hormonal assays and imaging tests to measure pulse wave velocity (PWV), augmentation index (AIx) and brachial artery flow-mediated vasodilation (FMD). Kolmogorov-Smirnov test showed normal distribution of most parameters. Unpaired Student t-test was used with significance level established at p < 0.05. Results: A total of 52 patients were included, 29 (56%) in PCOS group and 23 (44%) in control group. Clinical and laboratory parameters were similar between the groups. Women with PCOS had lower FMD (8.8 ± 1.0 vs 12.8 ± 1.2%, p = 0.021); PWV and AIx were similar between the groups (7.5 ± 0.2 vs 7.5 ± 0.3 m/s, p = 0.671 and 21.0 ± 1 vs. 20 ± 2%, p = 0.716, respectively). In the PCOS group, women with higher testosterone levels had higher AIx (25 ± 2 vs. 17 ± 3%, p = 0.045). Conclusions: PCOS women had endothelial dysfunction and those with higher testosterone levels had higher pulse wave reflection as compared with controls
Descritores: Síndrome do Ovário Policístico/complicações
Mulheres
Endotélio Vascular
-Testosterona
Artéria Braquial
Índice de Massa Corporal
Análise Estatística
Fatores de Risco
Síndrome Metabólica
Diabetes Mellitus
Aterosclerose
Dislipidemias
Sobrepeso
Hipertensão
HDL-Colesterol
LDL-Colesterol
Limites: Seres Humanos
Feminino
Adulto
Responsável: BR44.1 - Serviço de Biblioteca, Documentação Científica e Didática Prof. Dr. Luiz Venere Décourt


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Id: biblio-984523
Autor: Silva Junior, Delcio Gonçalves da; Costa, Izaias Pereira da.
Título: Cardiovascular Disease in Patients with Ankylosing Spondylitis from the Rheumatology Outpatient Clinic of the UFMS-affiliated Hospital
Fonte: Int. j. cardiovasc. sci. (Impr.);32(1):10-18, jan.-fev. 2019. tab, graf.
Idioma: en.
Resumo: Cardiovascular diseases are a major cause of morbidity and mortality today. Despite its wide distribution, it presents particularly prevalent in certain groups of individuals, particularly when exposed to a higher degree of inflammation, giving increased cardiovascular risk. Rheumatic diseases expose their holders to this increased cardiovascular risk condition; however only recently have been associated with spondyloarthritis, particularly ankylosing spondylitis (AS). For being a classically autoimmune disease related to HLA histocompatibility system, AS may present phenotypic variations in different ethnic groups with possible diverse cardiovascular consequences. Objectives: To estimate the prevalence of cardiovascular disease (CVD) and the cardiovascular risk profile, correlating the time since diagnosis and activity of ankylosing spondylitis (AS) in patients from the rheumatology outpatient clinic of the UFMS-affiliated hospital. Methods: Of 55 patients with AS, 42 were selected consecutively and compared to a control group (CG) in a cross-sectional study. Patients with diabetes, indigenous background and pregnant women were excluded. Quantitative variables were assessed by use of Student t test, while qualitative variables, by chi-square test. The patients underwent electrocardiography, echocardiography and carotid Doppler examination, measurement of serum lipid levels and inflammatory markers, and were stratified according to global cardiovascular risk. The AS activity and impairment were evaluated by use of the BASMI, BASDAI, BASFI and ASDAS. Results: Mean age, 42.87 ± 12.37 years; time since AS diagnosis, 10.76 ± 8.74 years. There was no difference in cardiovascular risk stratification between the groups, most of the patients being at high or moderate risk (AS: 64.3%, and CG: 52%, p = 0.134). The prevalence of manifest CVD (2%) showed no difference between the groups, except for right bundle-branch block (AS: 14%, and CG: 2%, p = 0.027). The prevalence of subclinical CVD showed no difference between the groups, except for higher carotid medial-intimal thickness (CIMT) in the AS group (AS: 1.82 ± 2.63, and CG: 0.67 ± 0.16, p = 0.018). There was no correlation between AS activity or inflammatory markers and CVD, but with time since AS diagnosis and CIMT (p = 0.039, r = 0.328). Conclusions: Prevalence of CVD and risk factors was similar in the groups. Subclinical atherosclerosis degree was higher in the AS group, related to the time since diagnosis, but was independent of the cardiovascular risk factors or inflammation. Most patients with AS are at high cardiovascular risk
Descritores: Pacientes Ambulatoriais
Espondilite Anquilosante/complicações
Espondilite Anquilosante/diagnóstico
Doenças Cardiovasculares
Doenças Reumáticas
-Ecocardiografia/métodos
Artérias Carótidas
Índice de Massa Corporal
Prevalência
Análise Estatística
Fatores de Risco
Síndrome Metabólica
Diabetes Mellitus
Eletrocardiografia/métodos
Aterosclerose
Hipertensão
HDL-Colesterol
LDL-Colesterol
Limites: Seres Humanos
Masculino
Feminino
Adulto
Responsável: BR44.1 - Serviço de Biblioteca, Documentação Científica e Didática Prof. Dr. Luiz Venere Décourt


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Id: biblio-954111
Autor: Cunha, Eduardo del Bosco Brunetti; Fagundes, Rafael Pereira; Scalabrin, Edson Emílio; Herai, Roberto Hirochi.
Título: Evaluation of Lipid Profile in Adolescents / Avaliação do Perfil Lipídico de Adolescentes
Fonte: Int. j. cardiovasc. sci. (Impr.);31(4):367-373, jul.-ago. 2018. tab, graf.
Idioma: en.
Resumo: Atherosclerosis is a chronic, multifactorial and insidious disease that can begin in childhood and adolescence, and whose major consequences appear during adulthood. Serum levels of lipoproteins, such as LDL-c, total cholesterol (TC), HDL-c, and non-HDL-c can be used as a screening method for disease diagnosis. In Brazil, few studies have correlated the serum levels of those lipoproteins with age. Objective: To evaluate the serum concentrations of TC, LDL-c, HDL-c, VLDL-c, non-HDL-c and triglycerides (TG) of adolescents aged 10 to 19 years in the municipality of Araucária, Paraná state. Methods: Cross-sectional retrospective study, collecting the following data from 600 adolescents: age, sex and serum levels of TC, LDL-c, HDL-c and TG from June to December 2016. Data were analyzed using the SPSS software 2.0, with Mann-Whitney U test and Spearman coefficient of correlation to identify statistical significance (p < 0.05). Results: The female sex showed higher serum levels of TC, TG and LDL-c than the male sex. The HDL-c levels were identical in both sexes, with 48% of desirable values and 52% of low values. This study identified a strong correlation between the lipids and association with the age group of 10 to 14 years. Conclusion: Non-HDL-c showed stronger correlation with the other lipids (TG, LDL-c and TC) as compared to LDL-c, suggesting that non-HDL-c can be used as an effective complementary diagnostic method to assess the risks for atherosclerosis in adolescents

A aterosclerose é uma doença crônica, multifatorial e insidiosa, podendo iniciar-se na infância ou adolescência, com suas principais consequências aparecendo na fase adulta. As dosagens séricas de lipoproteínas como LDL-c, colesterol total (CT), HDL-c e NÃO HDL-c podem ser usadas como forma de triagem de um diagnóstico. No Brasil há ainda pouquíssimos estudos correlacionando níveis séricos dessas lipoproteínas com a idade das pessoas. Objetivo: Avaliar as concentrações séricas de LDL-c, CT, HDL-c, NÃO HDL-c, VLDL-c e triglicerídeos (TG) em adolescentes de 10 a 19 anos do município de Araucária/PR. Métodos: Pesquisa transversal retrospectiva, que coletou os seguintes dados de 600 adolescentes: idade, sexo e dosagens de LDL-c, CT, HDL-c, NÃO HDL-c, VLDL-c e TG. Os dados foram avaliados com o programa de análise estatística SPSS 2.0, o teste U de Mann-Whitney e o coeficiente de correlação de Spearman para identificação de significado estatístico (p < 0,05). Resultados: O sexo feminino exprimiu níveis séricos de CT, TG e LDL-c maiores que o sexo masculino. O HDL-c apresentou valores idênticos em ambos os sexos, com 48% de valores desejáveis e 52% de baixos. O estudo identificou forte correlação entre as frações lipídicas e associação com a idade de 10 a 14 anos. Conclusão: Os resultados apontam que, em comparação ao LDL-c, o NÃO HDL-c apresentou maior correlação com as demais frações lipídicas (TG, LDL-c e CT), sugerindo que o NÃO HDL-c pode ser utilizado como um método eficaz na complementação de diagnóstico para avaliar riscos ateroscleróticos em adolescentes
Descritores: Adolescente
Dislipidemias/epidemiologia
Hipercolesterolemia
Lipoproteínas/metabolismo
-Doenças Cardiovasculares/mortalidade
Fatores Sexuais
Doença Crônica
Epidemiologia
Estudos Transversais
Análise Estatística
Fatores de Risco
Fatores Etários
Aterosclerose
HDL-Colesterol
LDL-Colesterol
Limites: Seres Humanos
Feminino
Adolescente
Responsável: BR44.1 - Serviço de Biblioteca, Documentação Científica e Didática Prof. Dr. Luiz Venere Décourt


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Id: lil-543994
Autor: Pinho, Cláudio; Pott Júnior, Henrique.
Título: Análise do risco de acidente vascular encefálico em pacientes portadores de fibrilação atrial / Analysis of the stroke risk in patients with atrial fibrillation
Fonte: Rev. Soc. Bras. Clín. Méd;8(2), mar.-abr. 2010. graf, tab.
Idioma: pt.
Resumo: JUSTIFICATIVA E OBJETIVOS: A fibrilação atrial (FA) é arritmia cardíaca frequente que está relacionada ao prejuízo hemodinâmico e eventos tromboembólicos, com consequente elevação de custos e morbimortalidade cardiovascular. A grande importância clínica da FA repousa no fato de que esta arritmia é a maior causa direta conhecida de acidente vascular encefálico isquêmico (AVEi). O objetivo deste estudo foi verificar se os fatores de risco associados ao AVE em pacientes com FA, estabelecidos na população norte-americana, podem ser aplicados em população de consultório.MÉTODO: Foram estudados os prontuários de 143 pacientes na faixa etária acima de 45 anos, com diagnóstico de FA atendidos em consultório de Cardiologia. Os parâmetros analisados foram: identificação do paciente; história da FA; presença de fatores de risco referidos na diretriz de FA do American College of Cardiology/American Heart Association (ACC/AHA), para AVE em pacientes com FA.RESULTADOS: A presença de doença aterosclerótica nas carótidas e tromboembolismo prévio mostrou significância estatística; os demais fatores não foram significativos. CONCLUSÃO: Dentre os 10 fatores de risco estabelecidos para a população norte-americana, somente dois foram significativos nessa população de consultório: doença aterosclerótica nas carótidas e evento tromboembólico prévio. Discutiram-se as possíveis causas que levaram os outros fatores a não apresentarem significância estatística.(AU)

BACKGROUND AND OBJECTIVES: Atrial fibrillation (AF) is common cardiac arrhythmia related to hemodynamic disturbance and thromboembolic events, with a consequent increase in costs and cardiovascular morbimortality. The great importance of clinical FA rests on the fact that this arrhythmia is the largest known direct cause of ischemic stroke. This study aimed to determine whether the risk factors associated with stroke in patients with AF established in the North American population, can be applied to a population of office in our country.METHOD: We studied the records of 143 patients in the age group over 45 years, diagnosed with FA treated in a cardiology clinic. The parameters were examined: identification data of the patient; data on the history of the FA; presence of risk factors listed in the guideline of the FA American College of Cardiology/American Heart Association (ACC/AHA) for stroke in patients with AF.RESULTS: The presence of carotid atherosclerosis and previous thromboembolism demonstrated statistical significance; whereas other factors where not significant.CONCLUSION: Among the ten risk factors established for the North American population, only two where significant in this population of office: carotid artery atherosclerosis and previous thromboembolism. The authors discuss possible causes that led to the other factors not present statistical significance.(AU)
Descritores: Fibrilação Atrial/fisiopatologia
Acidente Vascular Cerebral/epidemiologia
-Doenças das Artérias Carótidas/etiologia
Estudos Transversais/instrumentação
Fatores de Risco
Embolia/etiologia
Aterosclerose/etiologia
Limites: Seres Humanos
Tipo de Publ: Estudo Observacional
Responsável: BR1.1 - BIREME


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Id: biblio-884245
Autor: Wisniowski, Carlos.
Título: Hipertensión renovascular de origen ateroesclerótico. Diagnóstico y avances terapéuticos. / Atherosclerotic renovascular hypertension. Diagnosis and therapeutic breakthroughs
Fonte: Rev. Asoc. Med. Bahía Blanca;24(1):14-25, enero-marzo 2014.
Idioma: es.
Resumo: La hipertensión arterial renovascular (HARV) es una de las causas prevalentes de hipertensión arterial secundaria (HTA) contribuyendo a la causa de morbimortalidad cardiovascular y renal. El envejecimiento de la población y los factores de riesgo cardiovascular no adecuadamente controlados favorecen la aparición más frecuente de hipertensión arterial renovascular ateroesclerótica. Es frecuente que el médico clínico piense en esta eventualidad por lo que es necesario conocer las herramientas diagnósticas no invasiva e invasivas que actualmente están en uso para el diagnóstico y la evaluación del paciente con HARVA. Los resultados de distintos estudios randomizados publicados en los últimos años han posibilitado el cambio de algunas actitudes terapéuticas, jerarquizándose el tratamiento médico de HTA y de los factores que condicionan la progresión de la ateroesclerosis, una de cuyas consecuencias es la estenosis de la arteria renal. Las decisiones médicas deberán basarse en un análisis individual de cada paciente acorde a su complejidad y a la experiencia de cada centro.

Renovascular hypertension (RVHT) is one of the primary causes of secondary hypertension (HT) that contributes to cardiovascular and renal morbimortality. Population aging and improperly controlled cardiovascular risk factors are the reasons for a highest incidence of atherosclerotic renovascular hypertension. It is frequent for a clinician to consider this condition, therefore, it is necessary to know the non-invasive and invasive diagnostic tools available at present for RVHT patient diagnosis and assessment. The results of different randomized studies published in the last few years have promoted the change in some therapeutical attitudes, highlighting the medical treatment of HT and the factors that affect the progression of atherosclerosis, being renal artery stenosis one of the consequences of this. Medical decisions shall be based in the individual assessment of each patient according to the complexity and experience of each center.
Descritores: Hipertensão Renovascular
-Constrição Patológica
Aterosclerose
Limites: Seres Humanos
Tipo de Publ: Relatos de Casos
Responsável: AR393.1 - Centro de Información y Documentación Dr H. Urquiola


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Id: biblio-966150
Autor: Tentoni, Pablo; Silio, Julio; Orgaz, Federico; Fiorini, Diego; Vives, Daniel.
Título: Compresión traqueal por arteria subclavia derecha aberrante con divertículo de kommerell. Presentación de un caso y revisión de la literatura / Tracheal compression by aberrant right subclavian artery with kommerell's diverticulum. A case presentation and literature review
Fonte: Rev. Asoc. Med. Bahía Blanca;20(4):85-88, octubre-diciembre 2010.
Idioma: es.
Resumo: Se presenta una paciente de 80 años con estridor de etiología desconocida remitida a nuestra institución para la realización de una fibrobroncoscopía. Se la reevaluó y con la sospecha clínica de compresión vascular de la traquea se hicieron evidentes nuevos hallazgos. Se solicitaron nuevos estudios y se llegó al diagnóstico de compresión traqueal por arteria subclavia derecha aberrante con divertículo de Kommerell. Se realizó revisión bibliográfica al respecto.

An 80 year old female patient with stridor of unknown ethiology is referred to our institution for a fibrobronchoscopy. The patient was re-assessed due to clinical suspicion of vascular compression in the trachea and this lead to new and evident findings. New studies were requested and the final diagnosis was tracheal compression by aberrant right subclavian artery with Kommerell's diverticulum. A literature review was carried out.
Descritores: Artéria Subclávia
Traqueomalácia
-Divertículo
Aterosclerose
Limites: Seres Humanos
Tipo de Publ: Relatos de Casos
Responsável: AR393.1 - Centro de Información y Documentación Dr H. Urquiola


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Id: biblio-947789
Autor: Benozzi, Silvia; Alvarez, Cristina; Pennacchiotti, Graciela.
Título: Colesterol no-hdl: utilidad clínica de un marcador de riesgo cardiovascular ignorado / Non-hdl cholesterol: clinical use of an ignored cardiovascular risk marker
Fonte: Rev. Asoc. Med. Bahía Blanca;20(3):56-61, julio-septiembre 2010.
Idioma: es.
Resumo: Las enfermedades cardiovasculares constituyen la causa mas importante de morbi-mortalidad del siglo XXI. Las lipoproteínas aterogénicas juegan un rol fundamental en el desarrollo de las mismas. La evaluación de estas lipoproteínas en el laboratorio de análisis clínicos se puede realizar mediante la determinación de colesterol no-HDL, que se obtiene de la diferencia entre colesterol total y el colesterol transportado por las lipoproteínas de alta densidad. Se ha demostrado que esta variable es mejor predictora de enfermedades cardiovasculares que la determinación de colesterol transportado por las lipoproteínas de baja densidad (LDL), por lo que entidades científicas sugieren su incorporación en todos los informes del perfil lipídico. Es una herramienta útil para estimar el riesgo cardiovascular y evaluar tratamientos que reduzcan ese riesgo. A pesar de que su obtención es rápida, sencilla y accesible a todos los laboratorios, continpua siendo un marcador poco solicitado.

Cardiovascular diseases are the leading cause of morbidity and mortality of the 21st century. Atherogenics lipoproteins play a fundamental role in the development. In the clinical laboratory evaluation, these lipoproteins can be performed by determining non- HDL cholesterol, from the difference between total cholesterol and high-density lipoprotein cholesterol. It has shown that this variable is better predictor of cardiovascular diseases that low density lipoprotein cholesterol and entities suggest its incorporation on the lipid profile reports. It is a useful tool to estimate the cardiovascular risk and evaluating treatments to reduce that risk. While obtaining is fast, simple and accessible to all laboratories, continues to be a little requested marker.
Descritores: Lipoproteínas
HDL-Colesterol
-Doenças Cardiovasculares
Comportamento de Redução do Risco
Aterosclerose
Limites: Seres Humanos
Tipo de Publ: Estudos de Avaliação
Responsável: AR393.1 - Centro de Información y Documentación Dr H. Urquiola


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Id: lil-705640
Autor: Iglesias Marichal, Ileydis; Castelo Elías-Calles, Lizet; Domínguez Alonso, Emma; Mendoza Trujillo, Madelín.
Título: Adherencia terapéutica en pacientes con dislipoproteinemias / Adherence to treatment in patients with dyslipoproteinemias
Fonte: Rev. cuba. endocrinol;24(3):229-241, sep.-dic. 2013.
Idioma: es.
Resumo: Antecedentes: la adherencia terapéutica en las dislipoproteinemias es un elemento esencial en la prevención de las complicaciones de la aterosclerosis. Objetivos: determinar el nivel de adherencia en pacientes con dislipoproteinemias, e identificar los factores relacionados con esta. Métodos: estudio descriptivo, de corte transversal. Incluyó 91 sujetos que acudieron a la consulta de dislipoproteinemias en el Centro de Atención al Diabético del Instituto Nacional de Endocrinología, en La Habana, Cuba, en el periodo de enero a junio de 2011, con ³ 20 años de edad y al menos 12 semanas de asistir a la consulta. Fue aplicado un cuestionario anónimo y auto administrado, dividido en 3 secciones, que incluyeron variables relacionadas con la caracterización del grupo, como: sexo, grupo de edad, escolaridad, ocupación; categorías que describen la adherencia; y factores relacionados con esta. Se calcularon estadísticas descriptivas y se utilizó la prueba chi². Resultados: el rango de edad predominante fue de 40 a 59 años (94,9 por ciento). El 85,8 por ciento eran preuniversitarios, y el 40,7 por ciento de la muestra presentó adherencia terapéutica. El cumplimiento de la dieta, del horario y de las dosis de los fármacos se asoció significativamente con la adherencia terapéutica (p< 0,05). Conclusiones: la mayoría de los pacientes no presentaron adherencia terapéutica, en relación con el incumplimiento de la dieta y de la práctica de ejercicios. En un grupo menor de pacientes el cumplimiento del horario y la dosis del medicamento correspondieron con la mejor adhesión. Los factores que obstaculizan la adherencia terapéutica resultaron ser la carencia de frutas y vegetales en el mercado, así como también el abandono de la dieta. Los factores favorecedores fueron el adecuado apoyo familiar y la correcta información brindada por el médico de asistencia(AU)

Background: adherence to treatment in dyslipoproteinemias is an essential element for the prevention of atherosclerosis complications. Objectives: to determine the extent of adherence to treatment in patients with dyslipoproteinemias and to identify the factors related to it. Methods: a cross-sectional and descriptive study of 91 individuals who went to the dyslipoproteinemias service of the Center of Care for Diabetic Patients in the National Institute of Endocrinology in Havana, Cuba from January to June 2011. They were aged ³ 20 years and attended this service for at least 12 weeks. A self-administered anonymous questionnaire divided into 3 sections was applied; it included variables about the group characterization such as sex, age group, schooling, occupation, categories describing adherence to treatment and factors related to it. Summary statistics were estimated and chi-square test was used. Results: the predominant age group was 40 to 59 years (94.9 percent). In this sample, 85.8 percent had finished high school and 40.7 percent showed adherence to treatment. Compliance with diet, meal times and drug doses was significantly associated to adherence to treatment (p< 0.05). Conclusions: most of patients did not comply with treatment in terms of diet and exercising. In a lower number of patients, compliance with meal times and drug doses were related to better adherence to treatment. The factors hindering the adherence proved to be lack of fruits and vegetables at the marketplace as well as ignoring diet. The favoring factors were adequate family support and correct information provided by the attending physician(AU)
Descritores: Aterosclerose/complicações
Dislipidemias/prevenção & controle
Cooperação e Adesão ao Tratamento/estatística & dados numéricos
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Responsável: CU1.1 - Biblioteca Médica Nacional


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Id: lil-749222
Autor: Santos, João Manoel Theotonio dos.
Título: Aterosclerose: correlação entre aneurismas da aorta edoença arterial coronária / Atherosclerosis: correlation between aortic aneurysm and coronary artery disease
Fonte: Rev. Soc. Bras. Clín. Méd;13(1), abr. 2015.
Idioma: pt.
Descritores: Aneurisma Aórtico
Doença da Artéria Coronariana
Aterosclerose
-Medicina/tendências
Responsável: BR1.1 - BIREME



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