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Pesquisa : C17.800.716 [Categoria DeCS]
Referências encontradas : 99 [refinar]
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Id: biblio-983781
Autor: Garais, Josefina A; Bonetto, Verónica N; Frontino, Luciana; Salduna, María D; Ruiz Lascano, Alejandro.
Título: Granuloma aséptico facial idiopático: A propósito de un caso / Idiopathic facial aseptic granuloma: A case report
Fonte: Arch. argent. pediatr;117(1):56-58, feb. 2019. ilus.
Idioma: es.
Resumo: El granuloma aséptico facial idiopático (GAFI) es una afección de la infancia, que se caracteriza por nodulos faciales eritematovioláceos asintomáticos, usualmente confundidos con abscesos. Su patogénesis es desconocida, pero algunos autores han postulado su relación con la rosácea infantil. Se presenta el caso de un paciente con diagnóstico clínico de granuloma aséptico facial idiopático, con compromiso ocular y buena respuesta al tratamiento con metronidazol por vía oral.

Idiopathic facial aseptic granuloma is a childhood condition characterized by asymptomatic erythematous-violaceous nodules, often confused with abscesses. Its pathogenesis is unknown, but some authors have postulated its relationship with infantile rosacea. We present a case of a patient with a clinical diagnosis of idiopathic facial aseptic granuloma, with ocular involvement and a good response to oral metronidazole treatment.
Descritores: Pediatria
Terçol
Rosácea
Granuloma
Limites: Seres Humanos
Masculino
Lactente
Tipo de Publ: Relatos de Casos
Responsável: AR94.1 - Centro de Información Pediatrica


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Id: biblio-887113
Autor: Belli, Asli Akin; Altun, Ilknur; Altun, Ibrahim.
Título: Thickness of carotid intima and epicardial fat in rosacea: a cross-sectional study
Fonte: An. bras. dermatol;92(6):820-825, Nov.-Dec. 2017. tab.
Idioma: en.
Resumo: Abstract: Background: Rosacea is a chronic facial skin disease associated with excessive inflammatory response to various triggers. Although some studies have supported the increased risk of cardiovascular diseases in rosacea, it has not been completely accepted. Objective: We aimed to investigate epicardial fat thickness and carotid intima-media thickness as cardiovascular risk predictors in rosacea patients. Methods: We conducted a cross-sectional study including 40 rosacea patients and 40 controls. Demographic data, epicardial fat thickness, carotid intima-media thickness, lipid parameters, biochemical parameters, presence of insulin resistance, and presence of metabolic syndrome of the participants were recorded. Results: Forty rosacea patients (31 female and 9 male) and 40 controls (30 female and 10 male) were enrolled in the study. Rosacea patients had significantly higher epicardial fat thickness and carotid intima-media thickness volumes than controls (P<0.001). In the multivariate logistic regression analysis, epicardial fat thickness was independently related to presence of rosacea (P<0.001, OR=13.31). In the multiple linear regression analysis, the epicardial fat thickness was independently associated with rosacea (β= 0.47, P<0.001), carotid intima-media thickness (β= 0.36, P<0.001), and systolic blood pressure (β=0.19, P=0.015) and the carotid intima-media thickness was independently associated with epicardial fat thickness (β= 0.6, P<0.001). The epicardial fat thickness levels were correlated with carotid intima-media thickness (r=0.63, P<0.001), LDL (r=0.23, P=0.037), systolic blood pressure (r=0.45, P<0.001), and diastolic blood pressure levels (r=0.37, P=0.001). The carotid intima-media thickness levels were correlated with epicardial fat thickness (r=0.63, P<0.001), systolic blood pressure (r=0.04, P<0.001), and diastolic blood pressure levels (r=0.27, P=0.016). Study limitations: The small number of participants. Conclusions: Examination and follow-up of rosacea patients for cardiovascular diseases may be recommended practices.
Descritores: Pericárdio/patologia
Doenças Cardiovasculares/etiologia
Tecido Adiposo/patologia
Rosácea/complicações
Espessura Intima-Media Carotídea
-Pericárdio/fisiopatologia
Valores de Referência
Resistência à Insulina
Doenças Cardiovasculares/fisiopatologia
Estudos de Casos e Controles
Modelos Logísticos
Tecido Adiposo/fisiopatologia
Fatores de Risco
Rosácea/fisiopatologia
Estatísticas não Paramétricas
Síndrome Metabólica/fisiopatologia
Limites: Seres Humanos
Masculino
Feminino
Adulto
Meia-Idade
Responsável: BR1.1 - BIREME


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Id: biblio-887131
Autor: Cabral, Fernanda; Lubbe, Lara Caroline; Nóbrega, Monisa Martins; Obadia, Daniel Lago; Souto, Roberto; Gripp, Alexandre Carlos.
Título: Morbihan disease: a therapeutic challenge
Fonte: An. bras. dermatol;92(6):847-850, Nov.-Dec. 2017. graf.
Idioma: en.
Resumo: Abstract: Morbihan disease is a rare condition characterized by chronic and persistent erythematous solid edema localized on the face. It is believed to be a complication of rosacea and may occur at any stage of the disease. Features of this condition include variable therapeutic response and great refractoriness. We report a case of a 61-year-old man with rosacea history diagnosed with Morbihan disease, who showed excellent therapeutic response with the combination of deflazacort and oral isotretinoin but developed recurrence after corticosteroid discontinuation. We believe that in severe cases of lymphedema of the face this combination is effective and corticosteroid suspension should be done slowly and gradually.
Descritores: Pregnenodionas/uso terapêutico
Isotretinoína/uso terapêutico
Fármacos Dermatológicos/uso terapêutico
Eritema/tratamento farmacológico
Dermatoses Faciais/tratamento farmacológico
Anti-Inflamatórios/uso terapêutico
-Recidiva
Resultado do Tratamento
Rosácea/complicações
Eritema/patologia
Dermatoses Faciais/patologia
Linfedema/patologia
Linfedema/tratamento farmacológico
Limites: Seres Humanos
Masculino
Meia-Idade
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


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Id: biblio-973644
Autor: Tannus, Flávia Cisi; Picosse, Fabíola Rosa; Soares, Juliana Marques; Bagatin, Edileia.
Título: Rosacea-specific quality of life questionnaire: translation, cultural adaptation and validation for Brazilian Portuguese
Fonte: An. bras. dermatol;93(6):836-842, Nov.-Dec. 2018. tab.
Idioma: en.
Projeto: FAPESP.
Resumo: Abstract: Background: Brazil does not have a rosacea-specific quality of life questionnaire. Objectives: translation into Brazilian Portuguese, development of cultural adaptation, and validation of the RosaQoL disease-specific questionnaire for rosacea of any subtype. Methods: the recommended procedures for translation, cultural adaptation, and validation of an instrument were followed, and three interviews were conducted: baseline; seven to fourteen days after baseline; and at four to six months. The questionnaire was analyzed (with 95% confidence interval) for reliability by internal consistency (Cronbach's alpha); testretest reproducibility (intraclass correlation coefficient); responsiveness and validity. Results: terms of the original questionnaire were replaced to guarantee cultural and semantic equivalence. Validity was demonstrated by expressive correlations between the RosaQoL domains and by significance in the Jonckheere-Terpstra test (p≤0.05) between the scores of the RosaQoL domains and the participants' self-perception in relation to the disease. Reliability was acceptable; alpha coefficient ranged from 0.923 to 0.916 in the first and second applications of the RosaQoL, respectively, and the Intraclass Correlation Coefficient (ICC) ranged from 0.671 to 0.863 in the seven- to fourteen-day period. Responsiveness, measured by grouping participants into three categories based on self-perception of rosacea (better, worse or unchanged), was found for the "better" response group (p≤0.05). Study limitations: small sample; limited variety of screening sources. Conclusions: RosaQoL-BR (Brazil) was demonstrated as a reliable, valid and responsive questionnaire, with limitations, for individuals with any subtype of rosacea.
Descritores: Qualidade de Vida/psicologia
Rosácea/psicologia
-Traduções
Brasil
Inquéritos e Questionários
Reprodutibilidade dos Testes
Características Culturais
Linguagem
Limites: Seres Humanos
Masculino
Feminino
Adolescente
Adulto
Meia-Idade
Idoso
Adulto Jovem
Responsável: BR1.1 - BIREME


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Id: biblio-1001177
Autor: Di Matteo, María C; Stefano, Paola C; Cirio, Ana; López, Beatriz; Centeno, María; Bocian, Marcela; Cervini, Andrea B.
Título: Rosácea oculocutánea en un niño / Ocular and cutaneous rosacea in a child
Fonte: Arch. argent. pediatr;117(2):170-172, abr. 2019. ilus.
Idioma: es.
Resumo: La rosácea es una dermatosis crónica que se manifiesta clínicamente con eritema, telangiectasias, pápulas y pústulas en la parte central de la cara. Afecta, sobre todo, a los adultos y, en raras ocasiones, a los niños. La rosácea puede también presentar afección ocular y preceder, aparecer en forma simultánea o con posterioridad a las lesiones cutáneas; es mayor el riesgo de complicaciones oculares en los niños. La baja prevalencia de esta patología en la infancia origina demoras en el diagnóstico. Se presenta a un paciente de 1 año de edad con rosácea ocular y cutánea que desarrolló opacidades corneales con compromiso de la agudeza visual. Se destaca la importancia del diagnóstico y del tratamiento precoz para evitar el desarrollo de secuelas.

Rosacea is a chronic skin disease characterized by erythema, telangiectasia, papules and pustules in the central facial region. It most often affects adults and is rare in children. Rosacea can also present ocular involvement. Symptoms can precede cutaneous findings, appear simultaneously or after them, with a higher risk of ocular complications in children. Because of low prevalence of rosacea in childhood, the diagnosis is frequently delayed. We report a 1-year-old boy with ocular and cutaneous rosacea who developed corneal opacities and visual impairment. Early diagnosis and treatment is considerable to avoid sequels.
Descritores: Criança
Traumatismos Oculares
Rosácea
Limites: Seres Humanos
Masculino
Lactente
Tipo de Publ: Relatos de Casos
Responsável: AR94.1 - Centro de Información Pediatrica


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Id: biblio-827771
Autor: Tatu, Alin Laurentiu; Ionescu, Marius Anton; Clatici, Victor Gabriel; Cristea, Violeta Corina.
Título: Bacillus cereus strain isolated from Demodex folliculorum in patients with topical steroid-induced rosaceiform facial dermatitis
Fonte: An. bras. dermatol;91(5):676-678, Sept.-Oct. 2016. graf.
Idioma: en.
Projeto: European Social Fund.
Resumo: Abstract: The aim of the study was to identify Bacillus species from the Demodex folliculorum of patients with topical steroidinduced facial rosaceiform dermatitis. Of the 75 patients examined, 20% had clinical spinulosis, while 18.66% had dermoscopic features of Demodex: follicular plugs and tails. Of the 17.33% positive patients identified upon microscopy for Demodex, samples for bacterial culture were plated on trypticase soy Colombia agar. Identification was performed by microorganisms grown method mass spectrometry. We identified a strain of Bacillus cereus.
Descritores: Bacillus cereus/isolamento & purificação
Erupção por Droga/microbiologia
Rosácea/microbiologia
Ácaros/microbiologia
-Espectrometria de Massas
Telangiectasia/microbiologia
Telangiectasia/parasitologia
Erupção por Droga/parasitologia
Rosácea/induzido quimicamente
Rosácea/parasitologia
Limites: Seres Humanos
Animais
Responsável: BR1.1 - BIREME


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Id: biblio-837948
Autor: Vasconcelos, Rossana Cantanhede Farias de; Eid, Natália Trefiglio; Eid, Renata Trefiglio; Moriya, Fabíolla Sih; Braga, Bruna Backsmann; Michalany, Alexandre Ozores.
Título: Morbihan syndrome: a case report and literature review
Fonte: An. bras. dermatol;91(5,supl.1):157-159, Sept.-Oct. 2016. graf.
Idioma: en.
Resumo: Abstract Morbihan syndrome is a rare entity that more commonly affects women in the third or fourth decade of life. It is considered a special form of rosacea and its pathogenesis is not fully known. It is clinically characterized by the slow appearance of erythema and solid edemas on the upper portion of the face, with accentuation in the periorbital region, forehead, glabella, nose, and cheeks. We report the case of a patient presented with edema on the upper eyelid for a year. These findings suggested the diagnosis of Morbihan syndrome. We aim to report a rare, particularly refractory and chronic form of rosacea, which has received little attention in the literature.
Descritores: Rosácea/patologia
Edema/patologia
Eritema/patologia
-Síndrome
Biópsia
Doença Crônica
Derme/patologia
Doenças Palpebrais/patologia
Limites: Seres Humanos
Masculino
Adulto
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


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Id: biblio-837927
Autor: Coutinho, Jessica Castiel; Westphal, Danielle Cristine; Lobato, Laís Cruz; Schettini, Antônio Pedro Mendes; Santos, Mônica.
Título: Rosacea fulminans: unusual clinical presentation of rosacea
Fonte: An. bras. dermatol;91(5,supl.1):151-153, Sept.-Oct. 2016. graf.
Idioma: en.
Resumo: Abstract Rosacea fulminans or pyoderma faciale is a rare cutaneous disorder that usually affects women usually between the ages of 15-46. The disease is characterized by sudden onset of papules, pustules, cysts, and painful coalescing nodules with red-cyanotic centrofacial erythema. Although its etiology remains unknown, hormonal, immunological, and vascular factors have been reported. Early diagnosis and prompt treatment should minimize unsightly scars. We report a case of a 33-year-old female patient treated with traditional doses of doxycycline, with improvement of the lesions and regression of the condition in two months.
Descritores: Doxiciclina/uso terapêutico
Rosácea/patologia
Rosácea/tratamento farmacológico
Dermatoses Faciais/patologia
Dermatoses Faciais/tratamento farmacológico
Antibacterianos/uso terapêutico
-Resultado do Tratamento
Epiderme/patologia
Eritema/patologia
Eritema/tratamento farmacológico
Necrose
Limites: Seres Humanos
Feminino
Adulto
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


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Id: lil-776430
Autor: Addor, Flavia Alvim Sant'Anna.
Título: Skin barrier in rosacea
Fonte: An. bras. dermatol;91(1):59-63, Jan.-Feb. 2016. graf.
Idioma: en.
Resumo: Abstract Recent studies about the cutaneous barrier demonstrated consistent evidence that the stratum corneum is a metabolically active structure and also has adaptive functions, may play a regulatory role in the inflammatory response with activation of keratinocytes, angiogenesis and fibroplasia, whose intensity depends primarily on the intensity the stimulus. There are few studies investigating the abnormalities of the skin barrier in rosacea, but the existing data already show that there are changes resulting from inflammation, which can generate a vicious circle caused a prolongation of flare-ups and worsening of symptoms. This article aims to gather the most relevant literature data about the characteristics and effects of the state of the skin barrier in rosacea.
Descritores: Pele/fisiopatologia
Rosácea/fisiopatologia
-Pele/irrigação sanguínea
Fenômenos Fisiológicos da Pele
Perda Insensível de Água/fisiologia
Sebo/fisiologia
Rosácea/etiologia
Dermatite/fisiopatologia
Limites: Seres Humanos
Tipo de Publ: Revisão
Responsável: BR1.1 - BIREME


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Id: biblio-1046621
Autor: Mustafina, Gulgena Raisovna; Khismatullina, Zarema Rimovna.
Título: Modern aspects of rosacea therapy
Fonte: Prensa méd. argent;105(9 especial):576-581, oct 2019.
Idioma: en.
Resumo: This work is aimed at studying the problems of timely diagnostics and therapy of various forms of rosacea, identifying the factors that influence the compliance, prognosis, and quality of life of the patients, as well as the stages of combination therapy. The efficiency of rosacea therapy is determined by the timely identification of patients, as well as the clinical variety of the disease. Complex therapy of rosacea includes identification of the precipitating factors, basic skincare, and the use of systemic and local pathogenetic preparations. The "Gold Standard" of topical rosacea therapy is the antimicrobial and antiprotozoal drug called metronidazole. An important role in disease therapy is played by active cooperation between the doctor and the patient. Comprehensiveness, timeliness, and rationality of rosacea therapy are defined not only by the mechanisms of the disease development but also by aggravating factors, the need for basic care and photosensitivity of the patients
Descritores: Transtornos de Fotossensibilidade
Retinoides/uso terapêutico
Isotretinoína/uso terapêutico
Cooperação do Paciente
Tacrolimo/uso terapêutico
Rosácea/diagnóstico
Terapia Combinada
Metronidazol/uso terapêutico
Responsável: AR392.1 - Biblioteca



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