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Id: biblio-1001594
Autor: Candeiro, George Táccio de Miranda; Lavor, Amanda Bezerra; Lima, Ilana Thaís de Freitas; Vasconcelos, Bruno Carvalho de; Gomes, Nilton Vivacqua; Department of Restorative DentistryIglecias, Elaine Faga; Department of Restorative DentistryGavini, Giulio.
Título: Penetration of bioceramic and epoxy-resin endodontic cements into lateral canals
Fonte: Braz. oral res. (Online);33:e049, 2019. tab.
Idioma: en.
Resumo: Abstract: The aim of the present study was to assess the penetration capacity of two endodontic cements, Endosequence BC Sealer and AH Plus, in artificial lateral canals. Twenty-six two-rooted, maxillary first premolars were instrumented to size 40.06 using K3 files. In each root, six lateral canals of two diameters (0.06 and 0.10 mm) were created with a working length of 2, 4, and 6 mm. The specimens were randomly divided into two groups according to the endodontic cement to be used (Endosequence BC Sealer and AH Plus) and obturated by the single-cone technique. The specimens were imaged by digital periapical radiography and scores from 0 to 4 were attributed according to the degree of penetration by sealers into the lateral canals. Data were analyzed statistically by Kruskal-Wallis and Student-Newman-Keuls tests, and a significance level of p < 0.05 was adopted. No significant difference was observed between the two endodontic cements used to fill the simulated lateral canals (p > 0.05). The diameter of lateral canals only influenced the capacity of the Endosequence BC Sealer in filling the canals, and presented greater penetration in the lateral canals of diameter 0.10 mm (p < 0.05). We concluded that the bioceramic endodontic cement Endosequence BC Sealer presented similar ability as AH Plus to fill simulated lateral canals.
Descritores: Óxidos/química
Materiais Restauradores do Canal Radicular/química
Fosfatos de Cálcio/química
Cerâmica/química
Silicatos/química
Cavidade Pulpar/efeitos dos fármacos
Resinas Epóxi/química
-Valores de Referência
Obturação do Canal Radicular/métodos
Teste de Materiais
Distribuição Aleatória
Reprodutibilidade dos Testes
Estatísticas não Paramétricas
Combinação de Medicamentos
Limites: Humanos
Responsável: BR1.1 - BIREME


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Id: lil-584490
Autor: Delgado Fernández, Rafael; Urbizo Vélez, Joaquín; Rodríguez Sosa, Víctor; Iglesias Rodríguez, Enrique.
Título: Evaluación de la respuesta hística del beta fosfato tricálcico (Biograft-G) como implante óseo / Histological evaluation of tricalcium beta phosphate (Biograft-G) as bone implant
Fonte: Rev. cuba. estomatol;47(2):124-133, abr.-jun. 2010.
Idioma: es.
Resumo: Con el objetivo de determinar la histocompatiblidad y las propiedades de osteoconducción y biodegradación del Biograft-G (beta fosfato tricálcico sintético) obtenido por el Centro de Biomateriales de la Universidad de La Habana, se usaron para esta experiencia, 10 perros Beagle, a los cuales se les realizaron implantes de Biograft-G en fémur y mandíbula, con sus correspondientes controles. Estos animales fueron sacrificados en los siguientes periodos: a los tres y seis meses; y al año y dos años de implantados. Se obtuvo muestras de tejido en bloque del hueso implantado las cuales se fijaron en formol neutro y posteriormente procesadas, previa descalcificación, por el método de inclusión en parafina y coloreadas con Hematoxilina y Eosina. El estudio se realizó con microscopio óptico. Los resultados permitieron determinar que el Biograft-G resultó ser un material histocompatible, osteoconductor y biodegradable(AU)

With the aim to determine the histocompatibility, osteoconduction properties and biodegradation of synthetic tricalcium beta phosphate (Biograft-G) obtained in the Biomaterials Centre of Havana University we developed an experimental study using 10 Beagle dogs in which were placed Biograft-G implants in femur and jaw bones with their corresponding controls. The animals were sacrificed in three different periods: 3, 6 months, one and two years time of implantation. Block bone samples were obtained, fixed in 10 percent neutral formalin, decalcified and processed with the paraffin inclusion method and stained with Haematoxylin and Eosin. The study was carried out with optical microscope. We conclude that, according to the results obtained, Biograft-G is a histocompatible, osteoconductor and biodegradable material(AU)
Descritores: Fosfatos de Cálcio/uso terapêutico
Implantes Absorvíveis/efeitos adversos
Limites: Animais
Responsável: CU1.1 - Biblioteca Médica Nacional


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Id: biblio-990009
Autor: Alister, Juan Pablo; Uribe, Francisca; Vásquez, Bélgica; Fariña, Rodrigo; Olate, Sergio.
Título: Characterization of bone substitute beta946; -TCP block for maxillofacial reconstruction / Caracterización del bloque beta946; -TCP de sustitución ósea para la reconstrucción maxilofacial
Fonte: Int. j. morphol;37(1):82-86, 2019. tab, graf.
Idioma: en.
Projeto: Universidad de La Frontera; . Comisión Nacional de Investigación Científica y Tecnológica.
Resumo: SUMMARY: The aim of this study was to characterize a commercial beta tricalcium phosphate (β-TCP) block allograft for use in maxillofacial reconstruction, evaluating its homogeneity, porosity and mineralization. Two commercial 5 x 5 x10 mm chronOS Vivify β-TCP blocks were used, which were evaluated by a STEM SU-3500 variable pressure scanning electron microscope (SEM-STEM) (Hitachi, Japan). For the semi-quantitative microanalysis of elements, the QUANTAX 100 energy dispersive x-ray spectrometer detector (EDX) (Bruker, Germany) was used. The homogeneity of the structural morphology, macropore and micropore size and component homogeneity were evaluated. The microscopic analysis showed micropores of 164.92 mm (± 35.032 mm) in diameter in the outer area and micropores in the inner area of 54.44 mm (± 17.676 mm). The formation of porosities and irregularities present in the block was heterogeneous between the outer and inner surfaces. The mineral content of the blocks presented homogeneity with the presence of carbon (2.02 %), oxygen (44.33 %), phosphate (16.62 %) and calcium (37.87 %). The β-TCP block can be used in bone reconstruction but the presence of reduced macropore and micropore sizes could limit efficiency in the substitution and bone regeneration phase.

RESUMEN: El objetivo de este estudio fue caracterizar un aloinjerto de bloqueo de fosfato tricálcico (β-TCP) comercial para su uso en la reconstrucción maxilofacial, evaluando su homogeneidad, porosidad y mineralización. Se utilizaron dos bloques comerciales de 5 x 5 x 10 mm de vivify β-TCP de chronOS, que se evaluaron mediante un microscopio electrónico de barrido de presión variable STEM SU-3500 (SEM-STEM) (Hitachi, Japón). Para el microanálisis de elementos semicuantitativo, se utilizó el detector de espectrómetro de rayos X de dispersión de energía QUANTAX 100 (EDX) (Bruker, Alemania). Se evaluó la homogeneidad de la morfología estructural, el tamaño del macroporo y microporo y la homogeneidad de los componentes. El análisis microscópico mostró microporos de 164,92 mm (± 35,032 mm) de diámetro en el área externa y microporos en el área interna de 54,44 mm (± 17,676 mm). La formación de porosidades e irregularidades presentes en el bloque fue heterogénea entre las superficies externas e internas. El contenido mineral de los bloques presentó homogeneidad con la presencia de carbono (2,02 %), oxígeno (44,33 %), fosfato (16,62 %) y calcio (37,87 %). El bloque β-TCP se puede utilizar en la reconstrucción ósea, pero la presencia de macroporos y tamaños de microporos reducidos podría limitar la eficacia en la fase de sustitución y regeneración ósea.
Descritores: Fosfatos de Cálcio/uso terapêutico
Transplante Ósseo/métodos
Substitutos Ósseos/uso terapêutico
Procedimentos Cirúrgicos Reconstrutivos/métodos
-Regeneração Óssea
Microscopia Eletrônica de Varredura
Face/cirurgia
Tecidos Suporte
Aloenxertos
Maxila/cirurgia
Limites: Humanos
Responsável: CL1.1 - Biblioteca Central


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Texto completo SciELO Brasil
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Id: biblio-1056356
Autor: Wang, Shu; Zhang, Yitian; Zhang, Xin; Tang, Yuzhe; Li, Jianxing.
Título: Upper urinary tract stone compositions: the role of age and gender
Fonte: Int. braz. j. urol;46(1):70-80, Jan.-Feb. 2020. tab, graf.
Idioma: en.
Projeto: Capital Health Research and Development of Special; . Beijing Municipal Science and Technology Commission.
Resumo: ABSTRACT Objective: To analyze the compositions of upper urinary tract stones and investigate their distributions in different gender and age groups. Materials and Methods: Patients diagnosed with upper urinary tract stone disease between December 2014 and March 2018 were retrospectively reviewed. Patient's age, gender, BMI, comorbidities, stone event characteristics, and compositions were collected, and proportions of stone components in different gender and age groups were analyzed. Results: A total of 1532 stone analyses were performed (992 from males and 540 from females). The mean age was younger in males (p <0.001). Males included more cases with larger BMI, hyperuricemia, and obesity, while females had more urinary tract infections. Multiple components were present in 61.8% of stones. Calcium oxalate (CaOx) (67.0%) was the most common component, followed by uric acid (UA) (11.8%), infection stone (11.4%), calcium phosphate (CaP) (8.0%), cystine (1.1%), brushite (0.4%), and 2, 8-dihydroxyadenine (0.2%). Men contributed with more CaOx stones than women at age 30-49 years (all p <0.01) and more UA stones at 30-59 years (all p <0.05). Women contributed with more infection stones than men in age groups 30-49 and 60-69 years (all p <0.05), and more CaP stones at 30-49 years. The prevalence peak was 50-59 years in men and 60-69 years in women. Both genders had the lowest prevalence in adolescence. Prevalence of UA stones increased while that of infection stones decreased with aging in both genders. Conclusions: Age and sex had a strong association with distribution of stone compositions in this Chinese cohort.
Descritores: Cálculos Urinários/epidemiologia
Cálculos Urinários/química
Fatores de Risco
-Ácido Úrico/análise
Oxalato de Cálcio/análise
Fosfatos de Cálcio/análise
Adenina/análise
Adenina/análogos & derivados
Cálculos Urinários/etiologia
Modelos Logísticos
China/epidemiologia
Fatores Sexuais
Prevalência
Estudos Retrospectivos
Fatores Etários
Distribuição por Sexo
Distribuição por Idade
Pessoa de Meia-Idade
Limites: Humanos
Masculino
Feminino
Adulto
Responsável: BR1.1 - BIREME


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Id: biblio-1152205
Autor: Gómez, Marcelo Matias Mederos; Garcia, Isadora Martini; Leitune, Vicente Castelo Branco; Collares, Fabrício Mezzomo.
Título: Surface and mechanical properties of adhesives with calcium phosphates challenged to different storage media
Fonte: Braz. j. oral sci;19:e200181, jan.-dez. 2020. ilus.
Idioma: en.
Resumo: Aim: To evaluate the behavior of experimental dental adhesives with hydroxyapatite (HAp), alpha-tricalcium phosphate (α-TCP) or octacalcium phosphate (OCP) after storing them in three different media: dry storage, distilled water, or lactic acid. Methods: An experimental adhesive resin was formulated with bisphenol A glycol dimethacrylate, 2-hydroxyethyl methacrylate, and photoiniciator/co-initiator system. HAp(GHAp), α-TCP (Gα-TCP), or OCP (GOCP) were added to the adhesive resin at 2 wt.%, and one group remained without calcium phosphates to be used as a control (GCtrl). The adhesives were evaluated for surface roughness, scanning electron microscopy (SEM), and ultimate tensile strength (UTS) after storing in distilled water (pH=5.8), lactic acid (pH=4) or dry medium. Results: The initial surface roughness was not different among groups (p>0.05). GHAp showed increased values after immersion in water (p<0.05) or lactic acid (p<0.05). SEM analysis showed a surface variation of the filled adhesives, mainly for Gα-TCP and GHAp. GHApshowed the highest UTS in dry medium (p<0.05), and its value decreased after lactic acid storage (p<0.05). Conclusions: The findings of this study showed that HAp, OCP, and α-TCP affected the physical behavior of the experimental adhesive resins in different ways. HAp was the calcium phosphate that most adversely affected the surface roughness and the mechanical property of the material, mainly when exposed to an acid medium
Descritores: Polímeros
Resistência à Tração
Ácidos
Fosfatos de Cálcio
Adesivos Dentinários
Responsável: BR218.1 - Biblioteca Carlos Henrique Robertson Liberalli


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Id: biblio-1119562
Autor: Brasil, Luisa Rodrigues.
Título: Efeito da temperatura, concentração e volume dos reagentes na síntese de partículas de fosfato dicálcico dihidratado / Effect of temperature, concentration and reagent volume on the synthesis of dicalcium phosphate dihydrate.
Fonte: São Paulo; s.n; 20200000. 82 p.
Idioma: pt.
Tese: Apresentada a Universidade de São Paulo. Faculdade de Odontologia para obtenção do grau de Mestre.
Descritores: Fosfatos de Cálcio
Química
Responsável: BR97.1 - Serviço de Documentação Odontológica


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Id: biblio-1118656
Autor: Korenkov, Alexey.
Título: Influence of ß-tricalcium phosphate of different geometric shape on the morphology of regeneration of experimental defect of compact bone tissue / Influencia del fosfato ß-tricálcico de diferentes formas geométricas en la morfología de la regeneración del defecto experimental del tejido óseo compacto
Fonte: Actual. osteol;13(1):17-27, Ene - Abr. 2017. ilus.
Idioma: en.
Resumo: Purpose: to compare the healing process of a defect of compact bone tissue after the implantation of osteoplastic materials based on ß-tricalcium phosphate ("ChronOS™" and "Calc-i-oss®"), which differ by manufacturer, geometrical shape and microscopic structure. Methods: the experiment was performed on 48 white male Wistar rats. In the middle third of the diaphysis of the femur we produced a perforated defect of 2.5 mm diameter in the medullary canal, which in the animals of the first group was filled with the osteoplastic material "ChronOS™" (block, Synthes, Switzerland), and in the animals of the second group with "Calc-i-oss®" (granules, «Degradable Solutions Dental¼, Switzerland). Fragments of the injured bones were studied on the 60th and 120th day by light microscopy with morphometry and by scanning electron microscopy. Results: it was found that regardless the geometric shape and the microscopic structure, both osteoplastic materials show high biocompatibility, osteoconductive properties, good integration with bone tissue of the regenerate, and that the microscopic structure of ß-tricalcium phosphate ("ChronOS™") may significantly affect the microscopic structure of bone tissue of the regenerate, which manifests itself in the specificity of its geometric shape. It was noticed that osteoplastic materials "ChronOS™" and "Calc-i-oss®" almost at the same rate were subjected to resorption and replacement by the bone tissue, the ratio of which was 22.55±1.25 to 77.45±1.25 and 25.72±2.06% to 74.28±2.06% on the 60th day of the experiment, and 17.65±1.09 to 82.35±1.09 and 18.31±1.54% to 81.69±1.54% on the 120th day. (AU)

Objetivo: Comparar el proceso de cicatrización de un defecto del tejido óseo compacto tras la implantación de materiales osteoplásticos a base de fosfato ß-tricálcico («ChronOS™¼ and «Calc-i-oss®¼) que difieren según el fabricante en la forma geométrica y estructura microscópica. El estudio fue realizado en 48 ratas Wistar machos en los cuales se produjo, en el tercio medio de la diáfisis del fémur, un defecto perforado de 2,5 mm de diámetro, el cual fue llenado con el material «ChronOS™¼ (block, Synthes, Switzerland) en un grupo y con «Calc-i-oss®¼ (granules, «Degradable Solutions Dental¼, Switzerland) en el segundo grupo. El sector del defecto fue evaluado en los días 60 y 120 por microscopía óptica y por microscopía electrónica de barrido. Resultados: independientemente de la forma geométrica y la estructura microscópica, ambos materiales osteoplásticos mostraron alta biocompatibilidad, propiedades osteoconductivas y buena integración con el tejido óseo regenerado. La estructura microscópica del fosfato ß-tricálcico («ChronOS™¼) puede afectar significativamente a la estructura microscópica del tejido óseo regenerado, que se manifiesta en su forma geométrica. Adicionalmente, se observó que ambos materiales osteoplásticos «ChronOS™¼ y «Calc-i-oss®¼ mostraron valores similares de resorción y reemplazo por tejido óseo, cuya relación al 60º día del experimento fue de 22,55±1,25 a 77,45±1,25 y 25,72±2,06% a 74,28±2,06%, y a los 120 días de 17,65±1,09 a 82,35±1,09 y de 18,31±1,54% a 81,69±1,54% respectivamente. (AU)
Descritores: Fosfatos de Cálcio/uso terapêutico
Substitutos Ósseos/uso terapêutico
Fêmur/lesões
-Osteogênese
Próteses e Implantes
Materiais Biocompatíveis
Reabsorção Óssea
Teste de Materiais
Fosfatos de Cálcio/química
Ratos Wistar
Substitutos Ósseos/química
Fêmur/cirurgia
Fêmur/patologia
Fêmur/ultraestrutura
Ketamina/administração & dosagem
Acepromazina/administração & dosagem
Limites: Animais
Ratos
Tipo de Publ: Ensaio Clínico Veterinário
Responsável: AR2.1 - Biblioteca Central


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Texto completo SciELO Chile
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Id: biblio-1012355
Autor: Gutiérrez-Cantú, Francisco Javier; Magaña-Zamora, Guadalupe; Oliva-Rodríguez, Ricardo; García-Cortes, José Obed; Sánchez-Meraz, Wulfrano; Mariel-Cárdenas, Jairo.
Título: A comparative study of the biocompatibility of two root-end filling materials in rat connective tissue / Estudio comparativo de la biocompatibilidad de dos materiales de retro-obturación en tejido conectivo de rata
Fonte: Int. j. morphol;37(3):792-799, Sept. 2019. tab, graf.
Idioma: en.
Resumo: The aim of the present study was to examine the short-term biocompatibility of Endosequence Root Repair Material (ERRM) paste and white Mineral Trioxide Aggregate MTA by implanting them into polyethylene tubes in the subcutaneous connective tissue of rats. twenty five male Wistar rats, 3-4 months old, weighing 300-350 g, were used. The tubes were implanted dorsally into the subcutaneous connective tissues of the rats. Five animals were sacrificed at five examination time points: 1, 3, 5, 7 and 15 days. The connective tissues containing the implants were excised. These sections were studied qualitatively and quantitatively using a light microscope. An average value for each group was obtained by averaging the sum of all inflammatory cells counted in 10 randomly selected, separate areas. For the ERRM group: There was a significant increase in the number of inflammatory cells on days 1-3 and on days 5-7 (P ≤ 0.003 and P ≤ 0.024). In the WHITE MTA group, the mean values of the sum of the inflammatory cells during the periods 1-3 days and 5-7 days were statistically significant (P ≤ 0.001 and P ≤ 0.044, respectively) and the XILOPERCHA group: Difference was observed significant in the value of the sum of inflammatory cells during the period of 3-5 days (P ≤ 0.05). According to the results it can be concluded that both, ERRM as MTA, caused an inflammatory reaction, which decreased over time; suggesting that both materials are biocompatible; showing however the presence of a higher organization of collagen fibers around the implants of ERRM.

El objetivo del presente estudio fue evaluar la biocompatibilidad a corto plazo de Material de Reparación de la Raíz Endodóntica (MRRE) y el agregado de trióxido mineral (AgTM), implantándolos dentro de tubos de polietileno en el tejido conectivo subcutáneo de ratas. Se usaron 25 ratas Wistar macho, de 3-4 meses de edad, con peso de 300 a 350 g. Los tubos fueron implantados en el tejido conectivo subcutáneo del dorso de las ratas. Cinco animales fueron sacrificados en cada uno de los siguientes períodos de tiempo: 1, 3, 5, 7, y 15 días. El tejido conectivo con los implantes fue escindido y seccionado. Los cortes se evaluaron cualitativa y cuantitativamente mediante microscopio óptico. Se obtuvo un valor para cada grupo resultado al promediar la suma de las células inflamatorias contadas en 10 áreas separadas seleccionadas aleatoriamente. Para el grupo de MRRE; hubo un incremento significativo en la cantidad de células inflamatorias entre los días 1-3 y 5-7 (p ≤ 0,003 y p ≤ 0,024). En el grupo de AgTM blanco, los valores promedio de la suma de células inflamatorias entre los períodos 1-3 días, y 5-7 días mostraron ser estadísticamente significativos (p≤ 0,001 y p ≤ 0,044 respectivamente) y en el grupo control de Xilopercha se observó diferencia significativa entre los valores de la suma de células inflamatorias entre los períodos de 3-5 días (P ≤ 0,05). De acuerdo a los resultados, puede concluirse que ambos materiales, AgTM y MRRE causaron una reacción inflamatoria que disminuyó a través del tiempo, sugiriendo que ambos materiales son biocompatibles; mostrando sin embargo una mayor organización de fibras colágenas alrededor de los implantes de MRRE.
Descritores: Óxidos/farmacologia
Fosfatos de Cálcio/farmacologia
Silicatos/farmacologia
Compostos de Cálcio/farmacologia
Compostos de Alumínio/farmacologia
Tecido Conjuntivo/efeitos dos fármacos
-Materiais Restauradores do Canal Radicular/farmacologia
Teste de Materiais
Ratos Wistar
Combinação de Medicamentos
Limites: Animais
Masculino
Ratos
Tipo de Publ: Estudo Comparativo
Responsável: CL1.1 - Biblioteca Central


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Id: lil-609833
Autor: Carracedo Vizarreta, Mariana.
Título: El uso de fosfopéptidos de caseína como nueva alternativa para la remineralización del esmalte / The use than fosfopéptidos than caseíne sort of new alternative to the remineralización of the enamel
Fonte: Odontol. pediatr. (Lima);6(2):27-28, jul.-dic. 2007.
Idioma: es.
Descritores: Caseínas/uso terapêutico
Esmalte Dentário
Fosfatos de Cálcio/uso terapêutico
Fosfopeptídeos/uso terapêutico
Remineralização Dentária/métodos
Limites: Humanos
Tipo de Publ: Conferência Clínica
Responsável: PE1.1 - Oficina Universitária de Biblioteca


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Id: lil-619786
Autor: Pareja Vásquez, María del Carmen; Ascarza Acuña, Amílcar.
Título: Fosfato tricálcico beta como biomaterial de injertos óseos / Beta tricalcium phosphate as a biomaterial in bone grafts
Fonte: Kiru;4(1):29-34, ene.-jun. 2007. ilus.
Idioma: es.
Resumo: El propósito de esta revisión es presentar las características del beta fosfato tricálcico como material aloplástico para injertos en el área de periodoncia e implantología. Se han utilizado diversos tipos de materiales de injerto como los injertos autólogos, aloinjertos, injertos heterólogos y materiales aloplásticos, cada uno de ellos con características que los distingue y los convierte en una alternativa para tratamiento de defectos óseos y complementarios en la colocación de implantes inmediatos o en rebordes atróficos o en casos de elevación de piso de seno maxilar. El beta fosfato tricálcico ha sido evaluado en diversas investigaciones clínicas e histológicas, habiéndose encontrado que es un material altamente biocompatible y que ofrece buenos resultados. Asimismo, con este material no existe el riesgo de transmisión de enfermedades, como sí ocurre en el caso de los aloinjertos como el hueso liofilizado.

The purpose of this review is to present the characteristics of beta tricalcium phosphate as an alloplastic material for grafting in the field of periodontics and implantology. We have used various types of graft materials such as autologous grafts, allografts, heterologous grafts and alloplastic materials, each one with distinctive characteristics that make them an alternative for treatment of bone defects and to complement the immediate placement of implants or in cases of atrophic or elevated floor of the maxillary sinus. Beta tricalcium phosphate phosphate has been evaluated in various clinical and histological investigations that have found that it is a highly biocompatible material which provides good results. Likewise there is no material risk of disease transmission such as in allografts like lyophilisate bone.
Descritores: Fosfatos de Cálcio
Transplante Ósseo
Tipo de Publ: Revisão
Responsável: PE264.3 - Biblioteca



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