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Id: biblio-838679
Autor: Padilha, Bruno Gomes; Sabino, Daniela; Giorgi, Maria Clementina; Soares Jr, José; Izaki, Marisa; Meneghetti, José Claudio.
Título: Case Report: Multivessel Coronary Disease Assessment with SPECT 99mTc-Sestamibi and Rubidium-82 PET/CT / Relato de Caso: Investigação de Doença Multiarterial com 99mTc-Sestamibi e Rubídio-82 em PET-CT
Fonte: Arq. bras. cardiol;108(1):87-90, Jan. 2017. graf.
Idioma: en.
Descritores: Rubídio
Doença da Artéria Coronariana/diagnóstico por imagem
Tecnécio Tc 99m Sestamibi
Compostos Radiofarmacêuticos
Imagem de Perfusão do Miocárdio/métodos
Tomografia Computadorizada com Tomografia por Emissão de Pósitrons/métodos
-Doença da Artéria Coronariana/fisiopatologia
Reprodutibilidade dos Testes
Angiografia Coronária/métodos
Reserva Fracionada de Fluxo Miocárdico
Limites: Humanos
Feminino
Pessoa de Meia-Idade
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


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Id: biblio-882836
Autor: Tumax, Sonia M; Mancilla, Gabriela; Cabrera, Edith; Alvarado, Madaí; Cáceres, Armando.
Título: Evaluación del contenido de selenio en hojas de hierbas nativas de uso tradicional en la alimentación del guatemalteco / Evaluation of selenium content in leaves of native herbs of traditional food use in Guatemala
Fonte: Cienc. tecnol. salud;4(1):49-57, 20170600. tab.
Idioma: es.
Resumo: El selenio (Se) es un elemento esencial para el ser humano que se encuentra en pequeñas cantidades en los suelos, pero se acumula en ciertas plantas, proporcionando beneficios como antioxidante, antiinflamatorio y quemopreventivo por la presencia de unas 25 selenoproteínas que participan en diversas acciones de bienestar, lactancia, desarrollo, reproducción y salud de la progenie. El objetivo de este estudio fue evaluar el contenido de Se en hojas de vegetales utilizados tradicionalmente en la alimentación guatemalteca. Se colectaron hojas de materiales cultivados para los mercados locales de nueve hierbas nativas (Amaranthus hybridus, Cnidoscolus aconitifolius, Crotalaria longirostrata, Dysphania ambrosioides, Lycianthes synanthera, Sechium edule, Solanum americanum, Solanum nigrescens y Solanum wendlandii) y dos introducidas de reconocido uso alimenticio (Moringa oleifera y Spinacia oleracea), se secaron en un horno de convección forzada para lograr una humedad < 10% y se digirieron 0.25 ± 0.02 g de hojas en una mezcla de ácido nítrico y ácido perclórico que se calentó hasta la digestión total de la materia. El Se fue determinado por el método de reflexión total de rayos X, utilizando un estándar interno de itrio (Y) el que se midió utilizando reflectores de cuarzo en un espectrómetro de reflexión total de rayos X. De todas las especies evaluadas, únicamente A. hybridus demostró cantidades cuantificables de Se. Se determinó que 100 g de materia vegetal seca de A. hybridus proporciona 0.355 mg de Se, por lo que su consumo semanal puede contribuir con el requerimiento de este micronutriente para un adulto.

Selenium (Se) is an essential element for the human being; it is in small amounts in the soil but it accumulates in certain plants, providing benefits as antioxidant, anti-inflammatory and chemopreventive, due to the presence of about 25 selenoproteins that participate in different welfare and development actions, lactation, reproduction and health of the progeny. This study aimed to assess Se content in leaves of nine native plants traditionally used in Guatemalan food (Amaranthus hybridus, Cnidoscolus aconitifolius, Crotalaria longirostrata, Dysphania ambrosioides, Lycianthes synanthera, Sechium edule, Solanum americanum, Solanum nigrescens and Solanum wendlandii) and two internationally uses herbs (Moringa oleifera, Spinacia oleracea). Se was determined by total reflection X-ray method. Plants were dried in a forced convection oven to constant weight, then were digested by weighing 0.25 ± 0.02 g of dry plant material with a mixture of nitric and perchloric acid, and warmed to achieve complete digestion. Using a yttrium (Y) internal standard were measured using quartz reflectors Spectrometer Total reflection X-ray. Of all native plant species tested, only A. hybridus there were measurable amounts of Se. It was determined that 100 g of dry plant material of A. hybridus provides 0.355 mg of Se, so its weekly consumption by an adult might contribute to satisfied the requirement of this microelement.
Descritores: Amaranthus/crescimento & desenvolvimento
Rubídio/administração & dosagem
Estrôncio/análise
-Plantas Comestíveis/classificação
Limites: Humanos
Masculino
Feminino
Responsável: GT49.1


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Id: lil-592178
Autor: Sarquis, Otília; Oliveira, Lívia S; Rego, Reginaldo; Gonçalves, Jaylei M; Lima, Marli M; Maciel-de-Freitas, Rafael.
Título: Evaluation of RbCl and CrCl3 as markers of Triatoma brasiliensis (Hemiptera: Reduviidae) nymphs: persistence and influence of Rb and Cr on triatomine biology
Fonte: Mem. Inst. Oswaldo Cruz;106(4):385-389, June 2011. mapas, tab.
Idioma: en.
Resumo: In order to mark Triatoma brasiliensis, the vector of Chagas disease in Brazil, two chemical compounds, rubidium chloride (RbCl) and chromium chloride (CrCl3), were tested. First, 199 N2-N5 nymphs were fed on blood with 0.025M RbCl. Rb marker positivity ranged from 2.5 percent (N3)-70 percent (N2), with a maximum persistence of 98 days. Second, 265 N2-N5 nymphs were fed on blood containing 0.0015M CrCl3. Cr marker positivity ranged up to 93 percent (N5), with a maximum persistence of 119 days. Finally, we blood fed 213 T. brasiliensis to investigate whether CrCl3 altered the biology of this insect. The developmental time of T. brasiliensis was unaltered, but the survival of the Cr-marked group was lower than that of the control group. Differences in the mean fecundity of the control (mean of 156.1) and experimental (mean of 135.6) groups were not statistically significant and 100 percent of the egg batches of females Cr-marked as nymphs were positive. In conclusion, CrCl3 is a useful tool for marking T. brasiliensis nymphs due to its high positivity and persistence.
Descritores: Cloretos/farmacocinética
Compostos de Cromo/farmacocinética
Corantes/farmacocinética
Insetos Vetores/fisiologia
Ninfa/fisiologia
Rubídio/farmacocinética
Triatoma/fisiologia
-Doença de Chagas/transmissão
Fertilidade
Fertilidade/fisiologia
Insetos Vetores
Ninfa
Fatores de Tempo
Triatoma
Limites: Animais
Feminino
Tipo de Publ: Estudo de Avaliação
Responsável: BR1.1 - BIREME


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Id: lil-393763
Autor: Maciel-de-Freitas, Rafael; Gonçalves, Jaylei Monteiro; Lourenço-de-Oliveira, Ricardo.
Título: Efficiency of rubidium marking in Aedes albopictus (Diptera: Culicidae): preliminary evaluation on persistence of egg labeling, survival, and fecundity of marked female
Fonte: Mem. Inst. Oswaldo Cruz;99(8):823-827, dez. 2004. tab, graf.
Idioma: en.
Projeto: CNPq.
Resumo: Rubidium chloride (RbCl) has been used for the study of vector biology and behavior, although the efficacy of marking, egg production, and survivorship of marked females have been poorly studied. Four concentrations of RbCl were tested, among which 0.025 M was the best for marking Aedes albopictus: more than 80 percent of egg batches of females fed once with blood containing RbCl were marked; Rb-marked egg batches, interspersed with non marked ones were recovered until 61 days after a blood meal containing RbCl followed by non marked meals; RbCl was essentially detected in the abdomen of marked females, whose egg production and survivorship did not differ from non marked ones, at least in the three weeks following the Rb-marked blood meal.
Descritores: Aedes
Sistemas de Identificação Animal
Corantes
Insetos Vetores
Rubídio
-Fertilidade
Óvulo
Análise de Sobrevida
Fatores de Tempo
Limites: Animais
Feminino
Responsável: BR1.1 - BIREME


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Id: lil-334254
Autor: Honório, Nildimar Alves; Silva, Wellington da Costa; Leite, Paulo José; Gonçalves, Jaylei Monteiro; Lounibos, Leon Philip; Lourenço-de-Oliveira, Ricardo.
Título: Dispersal of Aedes aegypti and Aedes albopictus (Diptera: Culicidae) in an urban endemic dengue area in the State of Rio de Janeiro, Brazil
Fonte: Mem. Inst. Oswaldo Cruz;98(2):191-198, Mar. 15, 2003. ilus, mapas, tab.
Idioma: en.
Projeto: CNPq; . Papes-Fiocruz; . U.S. National Institutes of Health.
Resumo: Experimental releases of female Aedes (Stegomyia) aegypti and Aedes (Stegomyia) albopictus were performed in August and September 1999, in an urban area of Nova Iguaçu, State of Rio de Janeiro, Brazil, to estimate their flight range in a circular area of 1,600 m where 1,472 ovitraps were set. Releases of 3,055 Ae. aegypti and 2,225 Ae. albopictus females, fed with rubidium (Rb)-marked blood and surgically prevented from subsequent blood-feeding, were separated by 11 days. Rb was detected in ovitrap-collected eggs by atomic emission spectrophotometry. Rb-marked eggs of both species were detected up to 800 m from the release point. Eggs of Ae. albopictus were more numerous and more heterogeneously distributed in the area than those of Ae. aegypti. Eggs positively marked for Rb were found at all borders of the study area, suggesting that egg laying also occurred beyond these limits. Results from this study suggest that females can fly at least 800 m in 6 days and, if infected, potentially spread virus rapidly
Descritores: Aedes
Comportamento Animal
Voo Animal
Insetos Vetores
-Sistemas de Identificação Animal
Brasil
Cloretos
Comportamento Alimentar
Óvulo
Dinâmica Populacional
Rubídio
Espectrofotometria Atômica
População Urbana
Limites: Animais
Humanos
Feminino
Tipo de Publ: Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Responsável: BR1.1 - BIREME


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Burth, P
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Id: lil-188429
Autor: Younes-Ibrahim, M; Buffin-Meyer, B; Cheval, L; Burth, P; Castro-Faria, M. V; Barlet-Bas, C; Marsy, S; Doucet, A.
Título: Na, K-ATPase: a molecular target for Leptospira interrogans endotoxin
Fonte: Braz. j. med. biol. res = Rev. bras. pesqui. méd. biol;30(2):213-23, Feb. 1997. tab, graf.
Idioma: en.
Resumo: On the basis of our report that a glycolipoprotein fraction (GLP) extracted from Leptospira interrogans contains a potent inhibitor of renal Na,K-ATPase, we proposed that GLP-induced inhibition of Na,K-ATPase might be the primary cellular defect in the physiopathology of leptospirosis. The present study was designed to test this hypothesis by determining whether or not 1) GLP inhibits all the isoforms of Na,K-ATPase which are expressed in the tissues affected by leptospirosis, 2) Na,K-ATPase from leptospirosis-resistant species, such as the rat, is sensitive to GLP, 3) GLP inhibits Na,K-ATPase from intact cells, and 4) GLP inhibits ouabain-sensitive H,K-ATPase. The results indicate that in the rabbit, a leptospirosis-sensitive species, GLP inhibits with similar efficiency (apparent IC5O: 120-220 mug protein GLP/ml) all isoforms of Na,K-ATPase known to be expressed in target tissues for the disease. Na,K-ATPase from rat kidney displays a sensitivity to GLP similar to that of the rabbit kidney enzyme (apparent IC50: 25-80 and 50-150 mug protein GLP/ml for rat and rabbit, respectively), indicating that resistance to the disease does not result from the resistance of Na,K-ATPase to GLP. GLP also reduces ouabain-sensitive rubidium uptake in rat thick ascending limbs (pmol mm-1 min-1 ñ SEM; control: 23.8 ñ 1.8; GLP, 88 mug protein/ml: 8.2 ñ 0.9), demonstrating that it is active in intact cells. Finally, GLP had no demonstrable effect on renal H,K-ATPase activity, even on the ouabain-sensitive form, indicating that the active principle of GLP is more specific for Na,K-ATPase than ouabain itself. Although the hypothesis remains to be demonstrated in vivo, the present findings are compatible with the putative role of GLP-induced inhibition of Na,K-ATPase as an initial mechanism in the physiopathology of leptospirosis.
Descritores: Endotoxinas/toxicidade
ATPase Trocadora de Hidrogênio-Potássio/fisiologia
Técnicas In Vitro
Leptospira interrogans/patogenicidade
Leptospirose/fisiopatologia
Rubídio/metabolismo
ATPase Trocadora de Sódio-Potássio/fisiologia
-Encéfalo/citologia
Medula Renal/citologia
Limites: Animais
Coelhos
Tipo de Publ: Research Support, Non-U.S. Gov't
Responsável: BR1.1 - BIREME


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Id: lil-113255
Autor: Kuschnir, Emilio.
Título: Estudios hemodinámicos en la cardiopatía chagásica, con técnicas de radiotrazadores / Hemodynamic studies in the Chagasic cardiopathy, with technics of radiotracers.
Idioma: es.
Resumo: Trata estudios hemodinámicos en cardiopatía chagásica, iniciados hacia 1964, sobre la base de lautilización de técnicas no invasivas. En un comienzo, se intentó evaluar, en una serie de 90 pacientes y a través de la determinación radiocardiográfica, algunos parámetros derivados -indice cardíaco, volumen sistólico, y frecuencia cardíaca-; elaborándose una clasificación clínica-hemodinámica de la cardiopatía chagásica. En una segunda fase, se valoró la reserva cardíaca frente al esfuerzo; y, en una tercera fase, se estudió el comportamiento del clearence miocárdico de Rubidio 86 como parámetro de perfusión miocárdica o flujo miocárdico efectivo. Se muestran ejemplos de los efectos de drogas que esta metodologia permitió valorar en paciets chagásicos (efecto de isosorbide sublingual y efecto de Dipiridamol), y que se aplicó al estudio de pacientes chagásicos y no chagásicos marcapaseados crónicamente -239 marcapasos con un seguimiento máximo de 10 años-, estudiándose la performance ventricular del corazón marcapaseado crónicamente. Muestra imágenes de los bordes de isocuentas sistólica-diastólica, obtenidas en la computadora de la Cámara Gamma, iniciando así el estudio de las disquinesias, hipoquinesias o aquinesias de la miocardiopatía chagásica
Descritores: Cardiomiopatia Chagásica/diagnóstico
Doença de Chagas
Doença Crônica
Dipiridamol/farmacologia
Exercício Físico
Coração
Hemodinâmica
Isossorbida/farmacologia
Marca-Passo Artificial
Radioisótopos
Rubídio
-Cardiomiopatia Chagásica/efeitos dos fármacos
Cardiomiopatia Chagásica/patologia
Seguimentos
Limites: Humanos
Tipo de Publ: Relatos de Casos
Responsável: AR318.1 - Centro de Información
AR318.1/WC 705/POSSE/REUN.INT/1981


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Id: lil-62219
Autor: Font, C.
Título: Hipoxia y difunsión de 86 Rb en cerebro de rata / Hypoxia and diffusion of 86 Rh in rat brain
Fonte: Bol. estud. méd. biol;35(3/4):213-9, jul.-dic. 1987. tab, ilus.
Idioma: es.
Resumo: Se ha utilizado el Rb como análogo del ión K+ para determinar su constante de permeabilidad, (K, o PS) a nivel de la barrera hemato-encefálica, (BHE) de la rata. El método seguido es el de dilución de un indicador. La constante de permeabilidad para los animales control es de 0.92 ñ 0.02 M1. g-1.h-1, (corteza cerebral) y de 1.11 ñ 0.12 M1.g-1.h-1, (cerebelo de animales control). El valor K de los animales sometidos a hipoxia es de 0.24 ñ 0.01 M1.g-1.h-1, (corteza cerebral) y de 0.32 ñ 0.03 M1.g-1.h-1, (cerebelo)
Descritores: Hipóxia Encefálica/fisiopatologia
Radioisótopos/metabolismo
Rubídio/metabolismo
-Barreira Hematoencefálica
Limites: Animais
Tipo de Publ: Estudo Comparativo
Responsável: MX1.1 - CENIDSP - Centro de Información para Decisiones en Salud Pública



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