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Id: biblio-1051261
Autor: Massoud, Ramona; Hadiani, Mohammad Rasoul; Hamzehlou, Pegah; Khosravi-Darani, Kianoush.
Título: Bioremediation of heavy metals in food industry: application of Saccharomyces cerevisiae
Fonte: Electron. j. biotechnol;37:56-60, Jan. 2019. tab.
Idioma: en.
Projeto: Shahid Beheshti University of Medical Sciences.
Resumo: Heavy metals are natural elements in the Earth's crust that can enter human food through industrial or agricultural processing, in the form of fertilizers and pesticides. These elements are not biodegradable. Some heavy metals are known as pollutants and are toxic, and their bioaccumulation in plant and animal tissues can cause undesirable effects for humans; therefore, their amount in water and food should always be under control. The aim of this study is to investigate the conditions for the bioremediation of heavy metals in foods. Various physical, chemical, and biological methods have been used to reduce the heavy metal content in the environment. During the last decades, bioremediation methods using plants and microorganisms have created interest to researchers for their advantages such as being more specific and environmentally friendly. The main pollutant elements in foods and beverages are lead, cadmium, arsenic, and mercury, which have their own permissible limits. Among the microorganisms that are capable of bioremediation of heavy metals, Saccharomyces cerevisiae is an interesting choice for its special characteristics and being safe for humans, which make it quite common and useful in the food industry. Its mass production as the byproduct of the fermentation industry and the low cost of culture media are the other advantages. The ability of this yeast to remove an individual separated element has also been widely investigated. In countries with high heavy metal pollution in wheat, the use of S. cerevisiae is a native solution for overcoming the problem of solution. This article summarizes the main conditions for heavy metal absorption by S. cerevisiae.
Descritores: Saccharomyces cerevisiae/metabolismo
Biodegradação Ambiental
Indústria Alimentícia
Metais Pesados/metabolismo
-Arsênio
Leveduras
Cádmio
Remoção de Contaminantes
Absorção
Bioacumulação
Chumbo
Mercúrio
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-1045684
Autor: Nwokocha, CR; Spence, J; Barton, EN.
Título: Cadmium, nicotine and cigarettes: any hypertension paradox?
Fonte: West Indian med. j;62(6):487-488, July 2013.
Idioma: en.
Descritores: Pressão Sanguínea/efeitos dos fármacos
Cádmio/efeitos adversos
Doenças Cardiovasculares/induzido quimicamente
Fumar/efeitos adversos
Nicotina/efeitos adversos
-Fumar/epidemiologia
Fatores de Risco
Limites: Humanos
Tipo de Publ: Editorial
Responsável: BR1.1 - BIREME


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Id: biblio-1045782
Autor: Hoo Fung, LA; Rattray, VR; Lalor, GC.
Título: Cadmium in Jamaican bush teas / El cadmio en las tisanas Jamaicanas
Fonte: West Indian med. j;63(1):26-28, Jan. 2014. map, tab.
Idioma: en.
Resumo: Samples of Jamaican plants used as bush teas were collected from households in high soil-cadmium (Cd) areas of central Jamaica and analysed by graphite furnace atomic absorption spectrophotometry for total cadmium and for cadmium extractable with a hot water brew as prepared for human consumption to determine their contribution to dietary cadmium exposure. The concentrations ranged from < 0.03 to 6.85 µg/g for total Cd, between 1 and 15% of which was extracted with a hot water brew. One cup (200 ml) of the teas examined was found to contain < 0.04-1.18 µg of Cd and would contribute 0.1 - 0.3 µg of Cd to a person's dietary intake. This is significantly below the provisional tolerable weekly intake (PTWI) of 7 µg Cd/kg body weight established by theWorld Health Organization (WHO). While this suggests that bush tea consumption does not contribute significantly to the PTWI, some of the teas examined exceed the WHO recommendation of less than 0.3 mg/kg Cd for medicinal plants.

Muestras de plantas jamaicanas utilizadas en las tisanas o tés herbales, fueron recogidas de los hogares en zonas de Jamaica central, donde el suelo presenta un alto contenido de cadmio (Cd). Las muestras fueron analizadas mediante espectrofotometría de absorción atómica con horno de grafito para investigar el contenido total de cadmio así como el cadmio extraíble con una infusión de agua caliente, al preparar infusiones para el consumo humano, y determinar su contribución a la exposición al cadmio dietético. Las concentraciones fluctuaron de < 0.03 a 6.85 µg/g para el Cd total, extrayéndose entre el 1 y el 15% de este con una infusión de agua caliente. Una taza (200 ml) de las tisanas examinadas contenía < 0,04 - 1.18 µg de Cd, lo cual contribuiría 0.1 - 0.3 µg de Cd al consumo dietético de una persona. Esta cantidad se halla significativamente por debajo de la "Ingesta semanal tolerable provisional" (PTWI por sus siglas en inglés) establecidas en 7 µg Cd/kg peso corporal por la Organización Mundial de la Salud (OMS). Si bien esto sugiere que el consumo de tisanas no contribuye significativamente al PTWI, algunas de las infusiones examinadas exceden la recomendación de la OMS de menos de 0.3 mg/kg Cd para las plantas medicinales.
Descritores: Cádmio/análise
Chás de Ervas/análise
-Espectrofotometria Atômica
Jamaica
Responsável: BR1.1 - BIREME


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Id: biblio-1249995
Autor: Erostegui, C; Oporto, Carla; Zalles, Lourdes; Sevilla, Ricardo; Romero, Ana María.
Título: Evaluación del daño renal por cadmio en población expuesta a contaminación por éste en agricultores de Quila-Quila, Potosí / Evaluation of kidney damage by cadmium in a population exposed to its contamination in farmers from Quila-Quila, Potosí
Fonte: Gac. méd. boliv;43(2):143-146, dic. 2020. ilus.
Idioma: es.
Resumo: El cadmio es un metal pesado presente en desechos mineros y otros, y tiene efectos deletéreos en la salud humana especialmente en el riñón en el que destruye células tubulares. En una investigación de la calidad del lecho de los ríos que reciben aguas residuales en el norte de Potosí, Bolivia, se reportó presencia de cadmio en papas regadas con esa agua en Quila-quila, una población rural de la zona. OBJETIVO: de este trabajo fue el de identificar posibles daños del cadmio en la salud de los pobladores de Quila-quila. MÉTODOS: para ello se realizó revisión clínica y análisis laboratorial clínico y químico de sangre y orina de los pobladores de Quila-quila, y se calculó la tasa de filtración glomerular (TFG) y se correlacionó ésta con indicadores de lesión glomerular. RESULTADOS: se encontraron niveles elevados de cadmio en sangre en algunas personas, y una correlación de la TFG con la concentración de cadmio en sangre y con indicadores de lesión de membrana glomerular. CONCLUSIONES: en conclusión, los pobladores de Quila-quila estuvieron contaminados por cadmio, el cual produjo lesión renal leve.

Cadmium is a heavy metal present in mining and other wastes, and has deleterious effects on human health especially in the kidney in which it destroys tubular cells. In an investigation of the quality of the river beds that receive wastewater in the north of Potosí, Bolivia, the presence of cadmium was reported in potatoes watered with these water in Quila-quila, a rural town in the area. OBJECTIVE: of this work was to identify possible damage from cadmium to the health of the inhabitants of Quila-quila. METHODS: for this, clinical review and clinical and chemical laboratory analysis of blood and urine from the inhabitants of Quila-quila, and the filtration rate was calculated glomerular (GFR) and this was correlated with indicators of glomerular injury. RESULTS: elevated levels of cadmium were found in the blood in some people, and a correlation of GFR with blood cadmium concentration and indicators of membrane injury glomerular. CONCLUSIONS: in conclusion, the inhabitants of Quila-quila were contaminated by cadmium, which caused mild kidney damage.
Descritores: Cádmio
Taxa de Filtração Glomerular
-Poluição Ambiental
Filtração
Membranas
Limites: Humanos
Pessoa de Meia-Idade
Tipo de Publ: Estudo Observacional
Responsável: BO138.1 - Biblioteca Central


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Id: biblio-1093005
Autor: García, Juan Daniel Díaz; Arceo, Emmanuel.
Título: Renal damage associated with heavy metals: review work / Daño renal asociado a metales pesados: trabajo de revisión
Fonte: Rev. colomb. nefrol. (En línea);5(1):45-53, Jan.-June 2018. tab, graf.
Idioma: en.
Resumo: Abstract Catheter-associated infection is an entity with multiple complications, a condition that alters the quality of life of all patients Chronic kidney disease (CKD) represents an important health problem in the entire global population, where knowledge of the environmental factors associated with this disease is currently essential for its prevention. Several heavy metals are recognized, including Cadmium (Cd), Lead (Pb), Arsenic (As) and Mercury (Hg), which are clearly associated with renal damage and progression of CKD. Studies in animals and humans primarily demonstrate a clear association between exposure to these metals and the presence of chronic renal damage, where the pathophysiology of each of these metals is important in understanding the mechanism of renal damage. The present review aims to analyze the pathophysiology and clinical manifestations of the nephrotoxicity associated with these metals, as well as the different studies in both humans and animals that have been performed.

Resumen La enfermedad renal crónica (ERC) representa un importante problema de salud en todo el globo. Actualmente, es esencial para su prevención el conocimiento de los factores ambientales asociados con la enfermedad. Se reconocen diversos metales pesados, entre los que destacan el cadmio (Cd), plomo (Pb), arsénico (As) y mercurio (Hg), que están claramente asociados con la lesión renal y la progresión de la ERC. Estudios en animales y humanos demuestran, principalmente, una clara asociación entre la exposición a estos metales y la presencia de daño renal crónico, donde la fisiopatologia de cada uno de ellos es importante para entender el mecanismo de daño renal. La presente revisión tiene como objetivo analizar, tanto la fisiopatología y manifestaciones clínicas de la nefrotoxicidad asociada a dichos metales, como los diferentes estudios que se han realizado en humanos y animales.
Descritores: Metais Pesados
Insuficiência Renal Crônica
-Arsênio
Cádmio
Necrose Tubular Aguda
Chumbo
Mercúrio
Metais
Limites: Humanos
Masculino
Feminino
Tipo de Publ: Revisão
Responsável: CO661.9


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Id: biblio-950775
Autor: Muradoglu, Ferhad; Gundogdu, Muttalip; Ercisli, Sezai; Encu, Tarik; Balta, Fikri; Jaafar, Hawa ZE; Zia-Ul-Haq, Muhammad.
Título: Cadmium toxicity affects chlorophyll a and b content, antioxidant enzyme activities and mineral nutrient accumulation in strawberry
Fonte: Biol. Res;48:1-7, 2015. graf, tab.
Idioma: en.
Projeto: Yuzuncu Yil Universty of the head of scientific research.
Resumo: BACKGROUND: Cadmium (Cd) is well known as one of the most toxic metals affecting the environment and can severely restrict plant growth and development. In this study, Cd toxicities were studied in strawberry cv. Camarosa using pot experiment. Chlorophyll and malondialdehyde (MDA) contents, catalase (CAT), superoxide dismutase (SOD), ascorbate peroxidase (APX) activities and mineral nutrient concentrations were investigated in both roots and leaves of strawberry plant after exposure Cd. RESULTS: Cd content in both roots and leaves was increased with the application of increasing concentrations of Cd. We found higher Cd concentration in roots rather than in leaves. Chlorophyll a and b was decreased in leaves but MDA significantly increased under increased Cd concentration treatments in both roots and leaves. SOD and CAT activities was also increased with the increase Cd concentrations. K, Mn and Mg concentrations were found higher in leaves than roots under Cd stress. In general, increased Cd treatments increased K, Mg, Fe, Ca, Cu and Zn concentration in both roots and leaves. Excessive Cd treatments reduced chlorophyll contents, increased antioxidant enzyme activities and changes in plant nutrition concentrations in both roots and leaves. CONCLUSION: The results presented in this work suggested that Cd treatments have negative effect on chlorophyll content and nearly decreased 30% of plant growth in strawberry. Strawberry roots accumulated higher Cd than leaves. We found that MDA and antioxidant enzyme (CAT, SOD and APX) contents may have considered a good indicator in determining Cd tolerance in strawberry plant.
Descritores: Cádmio/toxicidade
Clorofila/metabolismo
Micronutrientes/metabolismo
Fragaria/efeitos dos fármacos
Antioxidantes/metabolismo
-Potássio/análise
Superóxido Dismutase/análise
Extratos Vegetais/química
Peroxidação de Lipídeos/efeitos dos fármacos
Catalase/análise
Clorofila/análise
Raízes de Plantas/efeitos dos fármacos
Raízes de Plantas/química
Folhas de Planta/efeitos dos fármacos
Folhas de Planta/química
Fragaria/metabolismo
Ascorbato Peroxidases/análise
Clorofila A
Magnésio/análise
Malondialdeído/análise
Manganês/análise
Tipo de Publ: Research Support, Non-U.S. Gov't
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-830543 LILACS-Express
Autor: Peláez-Peláez, Manuel José; Bustamante Cano, John Jairo; Gómez López, Eyder Daniel.
Título: Presencia de cadmio y plomo en suelos y su bioacumulación en tejidos vegetales en especies de brachiaria en el magdalena medio colombiano / Presence of cadmium and lead in soil and its accumulation in plant tissue in brachiaria species in the middle magdalena colombian
Fonte: Rev. luna azul;(43):82-101, jul.-dic. 2016. ilus, tab.
Idioma: es.
Resumo: En el Magdalena Medio colombiano confluyen dos actividades económicas: una ganadería intensiva y una consolidada industria petroquímica. Esta última representa un potencial peligro para la Salud Pública, como consecuencia de la emisión de metales tóxicos (plomo y cadmio) que pueden incorporarse a la cadena trófica. Por ello se realizó un inventario de pasturas en esta región en función de la distancia (100, 500, 2500 y 5000 m) al foco emisor contaminante. Así se muestrearon en zonas próximas a la refinería de crudo (Barrancabermeja, Santander), en pozos de extracción (Yondó, Antioquía) y tomando como testigo el Campus académico de la Universidad de la Paz (Barrancabermeja, Santander). Los resultados obtenidos indican una alta frecuencia de representantes de la familia Poaceae y de sus géneros de Brachiaria spp., con importantes diferencias. La información se interpretó en los tres primeros componentes, donde las variables con mayor peso fueron la profundidad del suelo a 5 y 30 cm, tipo de pastura con predominio de las especies introducidas y el transecto en relación a la distancia focal de las fuentes de contaminación. Así, en la zona de la refinería solo se han detectado dos especies de Brachiaria, mientras que en la zona de los pozos de extracción y en la zona testigo se presenta mayor frecuencia de otras especies de Brachiaria. Se concluye que los mayores niveles de bioacumulación de metales en tejidos vegetales presentó el siguiente orden: raíz > tallo > hojas, a su vez la acumulación en suelo mostró ser mayor en la profundidad de 5 cm.

In the Middle Magdalena Colombian converge two economic activities: intensive livestock and a consolidated petrochemical industry. The latter represents a potential danger to public health, resulting from the emission of toxic metals (lead and cadmium) that can enter in the food chain. Therefore pasture inventory is performed in this region depending on the distance (100, 500, 2500 and 5000 m) to the emitting source contaminant. So they were sampled near the oil refinery (Barrancabermeja, Santander) in extraction wells (Yondó, Antioquia) and sampling as witness the academic campus of the Universidad de la Paz (Barrancabermeja, Santander) areas. The results indicate a high frequency of representatives of the Poaceae family and its genera Brachiaria, with important differences. The information was interpreted in the first three components, where the variables with more weight were soil depth to 5 and 30 centimeters, type of pasture with predominance of introduced species and transect relative to the focal length of the sources of pollution. Then, in the area of the refinery were detected only two species of Brachiaria, while in the area of the extraction wells and in the control area it is presented a higher frequency of other species of Brachiaria. It's concluded that higher levels of bioaccumulation of metals in plant tissues presented the following order: root > stem > leaves, turn the accumulation in soil was found to be higher in the depth of 5 cm
Descritores: Poluentes Ambientais
-Cádmio
Brachiaria
Chumbo
Limites: Humanos
Tipo de Publ: Artigo Clássico
Responsável: CO54.1 - Centro de Biblioteca e Información Científica


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Id: biblio-1179284
Autor: Mohamdyari, Akram; Keshtmand, Zahra; Asghari Moghadam, Nastaran.
Título: Effect of crocin on PKHD1 and KLLN genes expression in kidney tissue of male rats treated with cadmium / Efecto de la crocina sobre la expresión de los genes PKHD1 y KLLN en tejido renal de ratas macho tratadas con cadmio
Fonte: Int. j. med. surg. sci. (Print);7(1):69-77, mar. 2020. tab, graf.
Idioma: en.
Resumo: According to data from studies, antioxidant herbal compounds are, likely to have a useful role in reducing the harmful effects of environmental pollutants and toxic chemicals that most people are exposed to. Cadmium is one of the toxic elements that accumulate in many organs, especially in kidneys. The aim of this study was to investigate the effect of crocin on the expression of PKHD1 and KLLN genes in cadmium-treated rats.In this experimental study, 40 adults male Wistar rats (200-250 g) were randomly divided into the following groups: control group received normal saline, cadmium group (15mg/kg), crocin group (20mg/kg) and cadmium group daily fed with crocin at a dose of 20 mg/kg.After eight weeks of treatment, rats were dissected, and kidney tissues were removed for evaluation of PKHD1 and KLLN gene expression by real time method. The data were analyzed using one-way ANOVA and significant difference between groups was P<0.05.Our results showed an increase in PKHD1 gene expression and a decrease in KLLN gene expression in kidney tissue in the cadmium group compared to the control group (P <0.001).Also, a significant decrease in PKHD1 gene expression (P <0.001) and an increase in KLLN gene expression P <0.05) were observed in the tissues of all cadmium-treated rats compared to cadmium.Crocin consumption can have a protective effect against the impaired expression of PKHD1 and KLLN cadmium-induced apoptotic pathway.

Diversos estudios sugieren que compuestos antioxidantes de hierbas tienen un papel útil en la reducción de los efectos nocivos de los contaminantes ambientales y los químicos tóxicos a los que está expuesta la mayoría de las personas. El cadmio es uno de los elementos tóxicos que se acumulan en muchos órganos, especialmente en los riñones. El objetivo de este estudio fue investigar el efecto de la crocina en la expresión de los genes PKHD1 y KLLN en ratas tratadas con cadmio.En este estudio experimental, 40 ratas Wistar macho adultas (200-250 g) se dividieron aleatoriamente en los siguientes grupos: el grupo de control recibió solución salina normal, el grupo de cadmio (15 mg / kg), el grupo de crocina (20 mg / kg) y el grupo de cadmio alimentado diariamente con crocina a una dosis de 20 mg / kg.Después de ocho semanas de tratamiento, se disecaron las ratas y se extrajeron los tejidos renales para evaluar la expresión de los genes PKHD1 y KLLN mediante un método en tiempo real. Los datos se analizaron mediante ANOVA de una vía y la diferencia significativa entre los grupos fue P <0,05.Nuestros resultados mostraron un aumento en la expresión del gen PKHD1 y una disminución en la expresión del gen KLLN en el tejido renal en el grupo de cadmio en comparación con el grupo de control (P <0,001).Además, se observó una disminución significativa en la expresión del gen PKHD1 (P <0,001) y un aumento en la expresión del gen KLLN P <0,05) en los tejidos de todas las ratas tratadas con cadmio en comparación con el cadmio.El consumo de crocina puede tener un efecto protector contra la expresión alterada de la vía apoptótica inducida por cadmio PKHD1 y KLLN.
Descritores: Cádmio/uso terapêutico
Carotenoides/farmacologia
Receptores de Superfície Celular/genética
Proteínas Supressoras de Tumor/genética
-Ratos Wistar
Neoplasias Renais/tratamento farmacológico
Limites: Animais
Ratos
Responsável: CL61.1 - Biblioteca Central Campus Sur


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Id: biblio-950868
Autor: Wang, Hui; Liu, Zheng; Zhang, Wenxiu; Yuan, Ziao; Yuan, Hongyi; Liu, Xueting; Yang, Chunwen; Guan, Weijun.
Título: Cadmium-induced apoptosis of Siberian tiger fibroblasts via disrupted intracellular homeostasis
Fonte: Biol. Res;49:1-14, 2016. ilus, graf.
Idioma: en.
Projeto: Natural Science Foundation of Liaoning Province; . Agricultural Science and Technology Innovation Program.
Resumo: BACKGROUND: Heavy metals can cause great harm to Siberian tigers in the natural environment. Cadmium (Cd2+) is an environmental contaminant that affects multiple cellular processes, including cell proliferation, differentiation, and survival. It has been shown to induce apoptosis in a variety of cell types and tissues. RESULTS: We investigated the apoptotic effects of Cd2+ on Siberian tiger fibroblasts in vitro. Our research revealed the typical signs of apoptosis after Cd²+ exposure. Apoptosis was dose- (0-4.8 µM) and duration-dependent (12-48 h), and proliferation was strongly inhibited. Cd²+ increased the activity of caspase-3, -8, and -9 and disrupted calcium homeostasis by causing oxidative stress and mitochondrial dysfunction. It also increased K+ efflux and altered the mRNA levels of Bax, Bcl-2, caspase-3, caspase-8, Fas, and p53. CONCLUSIONS: Our results suggest that Cd2+ triggers the apoptosis of Siberian tiger fibroblasts by disturbing intracellular homeostasis. These results will aid in our understanding of the effects of Cd2+ on Siberian tigers and in developing interventions to treat and prevent cadmium poisoning.
Descritores: Cádmio/toxicidade
Apoptose/efeitos dos fármacos
Espaço Intracelular/efeitos dos fármacos
Tigres
Fibroblastos/efeitos dos fármacos
Homeostase/efeitos dos fármacos
-Sibéria
Dano ao DNA
Ciclo Celular/efeitos dos fármacos
Células Cultivadas
Reação em Cadeia da Polimerase
Espécies Reativas de Oxigênio/análise
Apoptose/genética
Caspases/análise
Caspases/efeitos dos fármacos
Ensaio Cometa/veterinária
Microscopia Eletrônica de Transmissão
Transcrição Reversa
Potencial da Membrana Mitocondrial/efeitos dos fármacos
Fibroblastos/fisiologia
Homeostase/fisiologia
Limites: Animais
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-1159024
Autor: Angela Pérez, Adriana; Fajardo, María Angélica; Strobl, Analia Mabe; Pérez, Laura Beatriz; Piñeiro, Adriana; López, Clara Magdalena.
Título: Contenido de plomo, cromo y cadmio en moluscos comestibles del Golfo San Jorge (Argentina)
Fonte: Acta toxicol. argent;13(1):20-25, jul. 2005. ilus, tab.
Idioma: es.
Descritores: Argentina
Chumbo
Cromo
Cádmio
Impactos na Saúde
Moluscos
Responsável: PE8.1 - Biblioteca



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