Base de dados : LILACS
Pesquisa : D01.268.556.185 [Categoria DeCS]
Referências encontradas : 94 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 10 ir para página                        

  1 / 94 LILACS  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-1250256
Autor: Sartori, Giselle Pacifico; Costa, Andréa da; Macarini, Fernanda Lúcio dos Santos; Mariano, Douglas Oscar Ceolin; Pimenta, Daniel Carvalho; Spencer, Patrick Jack; Nali, Luiz Henrique da Silva; Galisteo Jr, Andrés Jimenez.
Título: Characterization and evaluation of the enzymatic activity of tetanus toxin submitted to cobalt-60 gamma radiation
Fonte: J. venom. anim. toxins incl. trop. dis;27:e20200140, 2021. graf, ilus.
Idioma: en.
Projeto: CAPES; . FAPESP; . FINEP; . CNPq.
Resumo: Tetanus toxin blocks the release of the inhibitory neurotransmitters in the central nervous system and causes tetanus and its main form of prevention is through vaccination. The vaccine is produced by inactivation of tetanus toxin with formaldehyde, which may cause side effects. An alternative way is the use of ionizing radiation for inactivation of the toxin and also to improve the potential immunogenic response and to reduce the post-vaccination side effects. Therefore, the aim of this study was to characterize the tetanus toxin structure after different doses of ionizing radiation of 60Co. Methods Irradiated and native tetanus toxin was characterized by SDS PAGE in reducing and non-reducing conditions and MALD-TOF. Enzymatic activity was measured by FRET substrate. Also, antigenic properties were assessed by ELISA and Western Blot data. Results Characterization analysis revealed gradual modification on the tetanus toxin structure according to doses increase. Also, fragmentation and possible aggregations of the protein fragments were observed in higher doses. In the analysis of peptide preservation by enzymatic digestion and mass spectrometry, there was a slight modification in the identification up to the dose of 4 kGy. At subsequent doses, peptide identification was minimal. The analysis of the enzymatic activity by fluorescence showed 35 % attenuation in the activity even at higher doses. In the antigenic evaluation, anti-tetanus toxin antibodies were detected against the irradiated toxins at the different doses, with a gradual decrease as the dose increased, but remaining at satisfactory levels. Conclusion Ionizing radiation promoted structural changes in the tetanus toxin such as fragmentation and/or aggregation and attenuation of enzymatic activity as the dose increased, but antigenic recognition of the toxin remained at good levels indicating its possible use as an immunogen. However, studies of enzymatic activity of tetanus toxin irradiated with doses above 8 kGy should be further analyzed.(AU)
Descritores: Radiação Ionizante
Tétano
Ensaio de Imunoadsorção Enzimática
Raios gama
-Toxina Tetânica
Cobalto
Responsável: BR68.1 - Biblioteca Virginie Buff D'Ápice


  2 / 94 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-976810
Autor: Etemadifar, Mohammad Reza; Andalib, Ali; Rahimian, Abbas; Nodushan, Seyed Mohamad Hossein Tabatabaei.
Título: Cobalt chromium-Titanium rods versus Titanium-Titanium rods for treatment of adolescent idiopathic scoliosis; which type of rod has better postoperative outcomes?
Fonte: Rev. Assoc. Med. Bras. (1992);64(12):1085-1090, Dec. 2018. tab, graf.
Idioma: en.
Resumo: SUMMARY OBJECTIVE; Compare the outcome of spinal deformity correction between Ti-Ti and CrCo-Ti rods for the treatment of spinal Adolescent Idiopathic Scoliosis (AIS) using rods mentioned with all pedicle screws and translation technique. METHOD; 59 patients operated for spinal deformity (Lenke 1 or 2) AIS. The patients were divided into two groups by random allocation using Ti-Ti rods (n = 29) and CrCo-Ti rods (n = 30) and the alone difference among them in the surgical procedure was rod material (Ti-Ti or CrCo-Ti rods) and finally, radiological outcomes were compared preoperatively, postoperatively and at last follow-up for 12 months. RESULTS; Patients' main curve correction after surgical procedure regardless type of rod was 48.95±11.04 (13-75) degree. Success rate of spinal deformity correction following surgical procedure regardless of type of administered rod was 86.76 ± 11.30 percent (62.5-100%). Mean of deformity correction rate was 91.49±10.67% using CrCo-Ti rods versus 81.86±9.88% using Ti-Ti rods (P-value=0.01). Angle change was 3.29±6.60 for kyphosis angle and 0.59±7.76 for lordosis angle. Rate of main curve correction was not significantly different considering patients' gender (P-value0.657). Main curve correction success rate was in association with patients' age and type of rod (P-value=0.054, r=-1.863 and P-value=0.001, r=8.865 respectively). CONCLUSION; CrCo-Ti rods have the ability to produce higher correction rates in AIS compared to Ti-Ti rod of the same diameter. CrCo-Ti rods provide significant and stable spinal correction, especially in correction of main curve. This rate was associated with patients' age and type of rod administered but not gender.

RESUMO OBJETIVO: Comparar o resultado da correção da deformidade da coluna vertebral com ligas de Ti-Ti e CrCo-Ti para o tratamento da Escoliose Idiopática do Adolescente (EIA) na coluna usando as ligas mencionadas com todos os parafusos pediculares e técnica de tradução. MÉTODO: 59 pacientes operados por EIA com deformidade da coluna vertebral (Lenke 1 ou 2). Os pacientes foram divididos em dois grupos por alocação aleatória usando ligas de Ti-Ti (n = 29) e ligas de CrCo-Ti (n = 30) e a única diferença entre eles no procedimento cirúrgico foi o material da liga (ligas de Ti-Ti ou CrCo-Ti) e, finalmente, resultados radiológicos foram comparados no pré-operatório, pós-operatório e no último retorno por 12 meses. RESULTADOS: A correção da curva principal do paciente após o procedimento cirúrgico, independentemente do tipo de liga, foi de 48,95±11,04 (13-75) graus. A taxa de sucesso da correção da deformidade da coluna vertebral após o procedimento cirúrgico, independentemente do tipo de liga administrada, foi de 86,76 ± 11,30% (62,5-100%). A média da taxa de correção da deformidade foi de 91,49±10,67% usando ligas de CrCo-Ti e 81,86±9,88% usando ligas de Ti-Ti (valor de P = 0,01). A mudança de ângulo foi de 3,29±6,60 para o ângulo de cifose e de 0,59±7,76 para o ângulo de lordose. A taxa de correção da curva principal não foi significativamente diferente considerando o sexo dos pacientes (Valor de P 0,657). A taxa de sucesso da correção da curva principal foi associada à idade do paciente e ao tipo de liga (valor de P=0,054, r=-1,863 e valor de P=0,001, r=8,865, respectivamente). CONCLUSÃO: As ligas de CrCo-Ti têm a capacidade de produzir taxas de correção mais altas em EIA em comparação com a liga de Ti-Ti do mesmo diâmetro. As ligas de CrCo-Ti fornecem uma correção espinhal significativa e estável, especialmente na correção da curva principal. Essa taxa foi associada à idade e ao tipo de liga administrada, mas não ao sexo.
Descritores: Desenho de Prótese
Escoliose/cirurgia
Fusão Vertebral/instrumentação
Fixadores Internos
Irã (Geográfico)
Cifose/cirurgia
-Escoliose/diagnóstico por imagem
Titânio
Pinos Ortopédicos
Radiografia
Ligas de Cromo
Resultado do Tratamento
Cobalto
Cifose/diagnóstico por imagem
Limites: Humanos
Masculino
Feminino
Criança
Adolescente
Tipo de Publ: Estudo Comparativo
Ensaio Clínico Controlado Aleatório
Responsável: BR1.1 - BIREME


  3 / 94 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Chile
Texto completo
Id: biblio-950834
Autor: Orozco-Ibarra, Marisol; Muñoz-Sánchez, Jorge; Zavala-Medina, Martín E; Pineda, Benjamín; Magaña-Maldonado, Roxana; Vázquez-Contreras, Edgar; Maldonado, Perla D; Pedraza-Chaverri, José; Chánez-Cárdenas, María Elena.
Título: Aged garlic extract and S-allylcysteine prevent apoptotic cell death in a chemical hypoxia model
Fonte: Biol. Res;49:1-10, 2016. ilus, graf.
Idioma: en.
Projeto: PAPIIT; . CONACYT; . Armstrong Foundation in México; . National Council of Science and Technology; . National Autonomous University of Mexico.
Resumo: BACKGROUND: Aged garlic extract (AGE) and its main constituent S-allylcysteine (SAC) are natural antioxidants with protective effects against cerebral ischemia or cancer, events that involve hypoxia stress. Cobalt chloride (CoCl2) has been used to mimic hypoxic conditions through the stabilization of the α subunit of hypoxia inducible factor (HIF-1α) and up-regulation of HIF-1α-dependent genes as well as activation of hypoxic conditions such as reactive oxygen species (ROS) generation, loss of mitochondrial membrane potential and apoptosis. The present study was designed to assess the effect of AGE and SAC on the CoCl2-chemical hypoxia model in PC12 cells. RESULTS: We found that CoCl2 induced the stabilization of HIF-1α and its nuclear localization. CoCl2 produced ROS and apoptotic cell death that depended on hypoxia extent. The treatment with AGE and SAC decreased ROS and protected against CoCl2-induced apoptotic cell death which depended on the CoCl2 concentration and incubation time. SAC or AGE decreased the number of cells in the early and late stages of apoptosis. Interestingly, this protective effect was associated with attenuation in HIF-1α stabilization, activity not previously reported for AGE and SAC. CONCLUSIONS: Obtained results show that AGE and SAC decreased apoptotic CoCl2-induced cell death. This protection occurs by affecting the activity of HIF-1α and supports the use of these natural compounds as a therapeutic alternative for hypoxic conditions
Descritores: Extratos Vegetais/farmacologia
Apoptose/efeitos dos fármacos
Cisteína/análogos & derivados
Fatores de Transcrição Hélice-Alça-Hélice Básicos/efeitos dos fármacos
Alho/química
Antioxidantes/farmacologia
-Sais de Tetrazólio
Hipóxia Celular/efeitos dos fármacos
Sobrevivência Celular/efeitos dos fármacos
Células Cultivadas
Análise de Variância
Células PC12
Espécies Reativas de Oxigênio/análise
Cobalto
Cisteína/farmacologia
Citometria de Fluxo
Formazans
Limites: Animais
Ratos
Tipo de Publ: Research Support, Non-U.S. Gov't
Responsável: CL1.1 - Biblioteca Central


  4 / 94 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Chile
Texto completo
Id: biblio-950847
Autor: Faisal, Mohammad; Saquib, Quaiser; Alatar, Abdulrahman A; Al-Khedhairy, Abdulaziz A; Ahmed, Mukhtar; Ansari, Sabiha M; Alwathnani, Hend A; Dwivedi, Sourabh; Musarrat, Javed; Praveen, Shelly.
Título: Cobalt oxide nanoparticles aggravate DNA damage and cell death in eggplant via mitochondrial swelling and NO signaling pathway
Fonte: Biol. Res;49:1-13, 2016. ilus, graf.
Idioma: en.
Projeto: National Plan for Science, Technology and Innovation; . King Abdul Aziz City for Science and Technology.
Resumo: BACKGROUND: Despite manifold benefits of nanoparticles (NPs), less information on the risks of NPs to human health and environment has been studied. Cobalt oxide nanoparticles (Co3O4-NPs) have been reported to cause toxicity in several organisms. In this study, we have investigated the role of Co3O4-NPs in inducing phytotoxicity, cellular DNA damage and apoptosis in eggplant (Solanum melongena L. cv. Violetta lunga 2). To the best of our knowledge, this is the first report on Co3O4-NPs showing phytotoxicity in eggplant. RESULTS: The data revealed that eggplant seeds treated with Co3O4-NPs for 2 h at a concentration of 1.0 mg/ml retarded root length by 81.5 % upon 7 days incubation in a moist chamber. Ultrastructural analysis by transmission electron microscopy (TEM) demonstrated the uptake and translocation of Co3O4-NPs into the cytoplasm. Intracellular presence of Co3O4-NPs triggered subcellular changes such as degeneration of mitochondrial cristae, abundance of peroxisomes and excessive vacuolization. Flow cytometric analysis of Co3O4-NPs (1.0 mg/ml) treated root protoplasts revealed 157, 282 and 178 % increase in reactive oxygen species (ROS), membrane potential (APm) and nitric oxide (NO), respectively. Besides, the esterase activity in treated protoplasts was also found compromised. About 2.4-fold greater level of DNA damage, as compared to untreated control was observed in Comet assay, and 73.2 % of Co3O4-NPs treated cells appeared apoptotic in flow cytometry based cell cycle analysis. CONCLUSION: This study demonstrate the phytotoxic potential of Co3O4-NPs in terms of reduction in seed germination, root growth, greater level of DNA and mitochondrial damage, oxidative stress and cell death in eggplant. The data generated from this study will provide a strong background to draw attention on Co3O4-NPs environmental hazards to vegetable crops.
Descritores: Óxidos/toxicidade
Dano ao DNA/efeitos dos fármacos
Morte Celular/efeitos dos fármacos
Cobalto/toxicidade
Solanum melongena/efeitos dos fármacos
Nanopartículas/toxicidade
Dilatação Mitocondrial/efeitos dos fármacos
Óxido Nítrico/metabolismo
-Óxidos/metabolismo
Análise de Variância
Espécies Reativas de Oxigênio/metabolismo
Cobalto/metabolismo
Ensaio Cometa
Solanum melongena/metabolismo
Microscopia Eletrônica de Transmissão
Nanopartículas/metabolismo
Citometria de Fluxo
Dilatação Mitocondrial/fisiologia
Tipo de Publ: Research Support, Non-U.S. Gov't
Responsável: CL1.1 - Biblioteca Central


  5 / 94 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Chile
Texto completo
Id: biblio-1011414
Autor: Rana, Nishant Kumar; Singh, Priya; Koch, Biplob.
Título: CoCl2 simulated hypoxia induce cell proliferation and alter the expression pattern of hypoxia associated genes involved in angiogenesis and apoptosis
Fonte: Biol. Res;52:12, 2019. graf.
Idioma: en.
Projeto: SERB-DST.
Resumo: BACKGROUND/AIMS: Hypoxia microenvironment plays a crucial role during tumor progression and it tends to exhibit poor prognosis and make resistant to various conventional therapies. HIF-1α acts as an important transcriptional regulator directly or indirectly associated with genes involved in cell proliferation, angiogenesis, apoptosis and energy metabolism during tumor progression in hypoxic microenvironment. This study was aimed to investigate the expression pattern of the hypoxia associated genes and their association during breast cancer progression under hypoxic microenvironment in breast cancer cells. METHODS: Cell proliferation in MCF-7 and MDA-MB-231 cell lines treated with different concentration of CoCl2 was analyzed by MTT assay. Flow cytometry was performed to check cell cycle distribution, whereas cell morphology was examined by phase contrast microscopy in both the cells during hypoxia induction. Expression of hypoxia associated genes HIF-1α, VEGF, p53 and BAX were determined by semiquantitative RT-PCR and real-time PCR. Western blotting was performed to detect the expression at protein level. RESULTS: Our study revealed that cell proliferation in CoCl2 treated breast cancer cells were concentration dependent and varies with different cell types, further increase in CoCl2 concentration leads to apoptotic cell death. Further, accumulation of p53 protein in response to hypoxia as compare to normoxia showed that induction of p53 in breast cancer cells is HIF-1α dependent. HIF-1α dependent BAX expression during hypoxia revealed that after certain extent of hypoxia induction, over expression of BAX conquers the effect of anti-apoptotic proteins and ultimately leads to apoptosis in breast cancer cells. CONCLUSION: In conclusion our results clearly indicate that CoCl2 simulated hypoxia induce the accumulation of HIF-1α protein and alter the expression of hypoxia associated genes involved in angiogenesis and apoptosis.
Descritores: Hipóxia Celular/efeitos dos fármacos
Cobalto/farmacologia
Apoptose/efeitos dos fármacos
-Transfecção
Hipóxia Celular/genética
Regulação Neoplásica da Expressão Gênica
Western Blotting
Apoptose/genética
Linhagem Celular Tumoral
Proliferação de Células/efeitos dos fármacos
Células MCF-7
Citometria de Fluxo
Limites: Humanos
Responsável: CL1.1 - Biblioteca Central


  6 / 94 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
Texto completo
Texto completo
Texto completo
Texto completo
Texto completo
Id: biblio-935076
Autor: Viegas, Claudio Castelo Branco.
Título: Dosimetria in vivo com uso de Detectores semicondutores e Termoluminescentes Aplicada ao tratamento de câncer de cabeça e pescoço / In vivo dosimetry with semiconductor and thermoluminescent detectors applied to head and neck cancer treatment.
Fonte: Rio de Janeiro; s.n; 2003. 43 p.
Idioma: pt.
Tese: Apresentada a Universidade Federal do Rio de Janeiro. Pós Graduação em Engenharia para obtenção do grau de Mestre.
Resumo: A dosimetria in vivo na radioterapia, i.e., a determinação da dose durante o tratamento, proporciona uma verificação da qualidade desse tratamento. Uma rotina de dosimetria in vivo é, incontestavelmente, um benefício direto para o paciente, mas, infelizmente, no Brasil e em toda a América Latina, ainda é um privilégio para poucos. Sabe-se que essa rotina é comum apenas nos países considerados desenvolvidos. Este trabalho demonstrou a viabilidade da implantação de uma rotina de dosimetria in vivo com uso de diodos semicondutores e dosímetros termoluminescentes (TLD), no setor de radioterapia do Instituto Nacional de Câncer (INCA), no caso de tratamento de câncer de cabeça e pescoço. Foram determinadas as características da resposta dos diodos ISORAD-p e detectores termoluminescentes de LiF:Mg;Ti (TLD-100) em forma de pó. Esses detectores foram testados quanto ao seu desempenho para as medidas in vivo no simulador antropomórfico RANDO Alderson e, uma vez comprovada a sua adaptabilidade às medidas propostas foram utilizados na medição de dose no caso de tratamento de tumores na região anatômica da cabeça e pescoço, utilizando irradiadores de Cobalto-60.

In vivo dosimetry in radiotherapy, i. e, the assessment of the doses received by patients during their treatments, permits a verification of the therapy quality. A routine of in vivo dosimetry is, undoubtedly, a direct benefit for the patient. Unfortunately, in Brazil and in Latin America this procedure is still a privilege for only a few patients. This routine is of common application only in developed countries. The aim of this work is to show the viability and implementation of a routine in vivo dosimetry, using diodes semiconductors and thermoluminescent dosimeters (TLD), at the radiotherapy section of the National Institute of Cancer in Brazil, in the case of head and neck cancer treatment. In order to reach that aim, the characteristics of the response of diodes ISORAD-p and LiF:Mg;Ti (TLD-100) thermoluminescent detectors in powder form were determined. The performance of those detectors for in vivo dosimetry was tested using an RANDO Alderson anthropomorfic phantom and, once their adequacy proved for the kind of measurements proposed, they were used for dose assessment in the case of tumour treatments in the head and neck regions, for Cobalt-60 irradiations.
Descritores: Dosimetria
Neoplasias de Cabeça e Pescoço/terapia
Radioterapia
-Cobalto
Limites: Humanos
Masculino
Feminino
Responsável: BR440.1 - Biblioteca Geraldo Matos de Sá . Hospital do Câncer I
BR440.1


  7 / 94 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-886722
Autor: BRUN, FLÁVIA G K; BRUN, ELEANDRO J; GERBER, DIONATAN; SZYMCZAK, DENISE A; LONDERO, EDUARDO K; MEYER, EVANDRO A; NAVROSKI, MÁRCIO C.
Título: Nutrition facts and limits for micronutrients in tree species used in urban forestry
Fonte: An. acad. bras. ciênc;89(3):1881-1893, July-Sept. 2017. tab.
Idioma: en.
Resumo: ABSTRACT There is a huge lack of researches that evaluate the nutritional limits in tree species used in urban forestry, especially in terms of micronutrients. This study aimed to establish limits and range of micronutrients levels for the proper development of tree species utilized in urban forestry. The study was conducted in the city of Santa Maria-RS-Brazil. Through forest inventory, 23 forest species present in urban forest were selected, and 05 vegetative branches of each tree were collected, in which the contents of B, Cu, Fe, Mn and Zn were analyzed. Ranges of micronutrients' contents were developed for class limits criteria. Nutritional problems were detected for B, Cu and Zn in G. robusta and S. cumini, indicating a need of fertilization and management of these trees. The levels of Mn were within an adequate range only for the species C. illinoensis and H. chrysotrichus. The contents of B were higher than the level considered adequate for H. chrysotrichusand M. nigra. The rates of Fe showed high levels for E. japonica, H. chrysotrichusand S. babylonica. The estimated nutritional limits enable a greater control in the classification of the results for each tree species utilized in urban forestry.
Descritores: Florestas
Micronutrientes/análise
-População Urbana
Zinco/análise
Cobalto/análise
Cobre/análise
Ferro/análise
Manganês/análise
Responsável: BR1.1 - BIREME


  8 / 94 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Mendonça, Carla Lopes de
Texto completo
Id: lil-666070
Autor: Santos, Rogério Adriano dos; Campos, Anne Grace S. S; Afonso, José Augusto B; Soares, Pierre Castro; Mendonça, Carla Lopes de.
Título: Efeito da administração de propileno glicol e cobalto associado à vitamina B12 sobre o perfil metabólico e a atividade enzimática de ovelhas da raça Santa Inês no periparto / Effect of propylene glycol, cobalt and vitamin B12 on the metabolic profile and enzymatic in Santa Inês ewes in peripartum
Fonte: Pesqui. vet. bras = Braz. j. vet. res;32(supl.1):60-66, Dec. 2012. ilus, tab.
Idioma: pt.
Resumo: (AU)O presente estudo teve por objetivo avaliar a influência da administração de propileno glicol e cobalto associado à vitamina B12 sobre o perfil metabólico e a atividade enzimática de ovelhas da raça Santa Inês no período do periparto. Foram utilizadas 18 ovelhas prenhes, pesando em torno de 40kg. Aproximadamente 30 dias antes da data prevista para o parto foram separadas de maneira aleatória em três grupos e administrados os suplementos conforme a seguir: (G1/n=6) grupo que recebeu propileno glicol (30mL por via oral diariamente); (G2/n=6) grupo que recebeu cobalto (1mg de cloreto de cobalto a 1%, via oral diariamente) associado a vitamina B12 (2mg via intramuscular, semanalmente) e (G3/n=6) grupo controle. As amostras de sangue das ovelhas para avaliação do perfil metabólico e enzimático (glicose, β-hidroxibutirato-BHB, NEFA, proteína total, albumina, uréia, creatinina, AST, GGT, FA e CK) foram colhidas 30 dias antes da data prevista para o parto, uma semana antes (ante-parto), no parto, às 24h, 72h, 5 dias, 15 dias e 30 dias após o parto. Não foi observado cetonúria nos momentos que antecederam ao parto. A administração dos suplementos não influenciou sobre o perfil metabólico, protéico e energético, assim como não houve comprometimento hepático das ovelhas no período do periparto.(AU)

The aim of this study was to evaluate the influence of the administration of propylene glycol and cobalt associated with vitamin B12 on the metabolic profile and enzymatic activity of Santa Inês ewes in the peripartum period. A total of 18 pregnant ewes, weighing around 40kg were used. Approximately 30 days before the expected date of delivery were randomly separated into three groups and administered supplements as follows: (G1/n = 6) group received propylene glycol (30mL orally daily); (G2/n = 6) group receiving cobalt (1mg cobalt chloride 1%, orally daily) associated with vitamin B12 (2mg intramuscular weekly) and (G3/n = 6) control group. Blood samples from ewes to evaluate the enzymatic and metabolic profile (glucose, β-hydroxybutyrate, BHB, NEFA, total protein, albumin, urea, creatinine, AST, GGT, ALP and CK) were taken 30 days before the date set for delivery, one week before (ante partum), delivery at 24h, 72h, 5 days, 15 days and 30 days after delivery. ketonuria was not observed in pre partum. The administration of supplements had no effect on the metabolic profile, protein and energy, and no liver disorders was observed in peripartum.(AU)
Descritores: Vitamina B 12/análise
Ovinos/metabolismo
Cobalto/análise
Propilenoglicol
-Período Periparto
Limites: Animais
Responsável: BR68.1 - Biblioteca Virginie Buff D'Ápice


  9 / 94 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Id: lil-409597
Autor: Echevarría Escribens, Carlos; Fernández Vozmediano, José M; Armario, José Carlos; González, Antonio.
Título: Estudio retrospectivo de la sensibilización a cloruro de cobalto / Retrospective study of sensitivity to cobalt clorure
Fonte: Folia dermatol. peru;15(1):18-22, ene.-abr. 2004. ilus, tab.
Idioma: es.
Resumo: Las sales de cobalto son agentes sensibilizadores habituales, que suelen observarse asociados a otros alergenos, en especial sulfato de níquel. Presentamos un estudio epidemiológico con el fin de establecer cuales son las características de nuestros pacientes con dermatitis alérgica de contacto, principalmente a la dermatitis alérgica de contacto a cloruro de cobalto. En la muestra estudiada, la sensibilización a cloruro de cobalto resultó la segunda en frecuencia (25.4 por ciento) siendo la asociación más frecuente con sulfato de níquel y dicromato potásico, con los que hemos encontrado una relación estadísticamente significativa. Es más frecuente en mujeres jóvenes trabajadoras del hogar con eczema de manos. La sensibilización concominante de cloruro de cobalto, sulfato de níquel y dicromato potásico se relaciona más con una exposición múltiple que con una reacción cruzada entre dichos alergenos. La sensibilización aislada a cloruro de cobalto representó el 6.5 por ciento en nuestro estudio, lo que coincide con el concepto de que la sensibilización aislada a dicloruro de cobalto es excepcional. No hemos encontrado ningún caso de alergia aislada a cloruro de cobalto en trabajadores de la construcción.
Descritores: Dicromato de Potássio
Sulfatos
Cloretos
Cobalto
Metais
Dermatite Alérgica de Contato
Níquel
-Estudos Transversais
Estudos Retrospectivos
Epidemiologia Descritiva
Estudos Epidemiológicos
Limites: Humanos
Masculino
Adulto
Feminino
Responsável: PE1.1 - Oficina Universitária de Biblioteca


  10 / 94 LILACS  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-1038256
Autor: Suzuki, Nathalie Mie; Duarte, Ida Alzira Gomes; Hafner, Mariana de Figueiredo Silva; Lazzarini, Rosana.
Título: Nickel exposure from keys: a Brazilian issue
Fonte: An. bras. dermatol;92(5):734-735, Sept.-Oct. 2017. graf.
Idioma: en.
Resumo: Abstract: Keys are a significant source of exposure to metal allergens and can be a relevant problem for nickel-allergic individuals. This study aimed to perform nickel and cobalt spot testing among the 5 most common Brazilian brands of keys. Among the tested keys, 100% showed positive result to nickel spot test, 83,3% presented strong positive reaction. 50% exhibited cobalt release as well. Nickel release from keys is very common in our country and may cause a negative impact on sensitized individual's quality of life. Study's results highlight the importance of establishing directives to regulate nickel release in Brazil.
Descritores: Cobalto/administração & dosagem
Dermatite Alérgica de Contato/etiologia
Níquel/administração & dosagem
-Brasil
Testes do Emplastro
Cobalto/análise
Qualidade de Produtos para o Consumidor
Exposição Ambiental
Utensílios Domésticos
Níquel/análise
Limites: Humanos
Responsável: BR1.1 - BIREME



página 1 de 10 ir para página                        
   


Refinar a pesquisa
  Base de dados : Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde