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Id: biblio-951962
Autor: Wainstein, Marcela; Morgental, Renata Dornelles; Waltrick, Silvana Beltrami Gonçalves; Oliveira, Sílvia Dias; Vier-Pelisser, Fabiana Vieira; Figueiredo, José Antonio Poli; Steier, Liviu; Tavares, Cauana Oliva; Scarparo, Roberta Kochenborger.
Título: In vitro antibacterial activity of a silicone-based endodontic sealer and two conventional sealers
Fonte: Braz. oral res. (Online);30(1):e18, 2016. tab, graf.
Idioma: en.
Projeto: FAPERGS.
Resumo: Abstract The aim of this study was to evaluate whether the modification in the silver component is capable of providing GuttaFlow 2 with antibacterial activity against Enterococcus faecalis compared with epoxy resin-based (AH Plus) and zinc oxide and eugenol-based (Endofill) sealers. The antibacterial activity was evaluated using a reference strain of E. faecalis (ATCC 29212). Freshly mixed sealers were subjected to the agar diffusion test (ADT), while the direct contact test (DCT) was performed after materials setting. ADT results were obtained through measurements, in millimeters, of the inhibition zones promoted by the materials, using a digital caliper. In DCT, values of CFU/mL promoted by the three sealers were compared in three experimental periods (1 min, 1 h, and 24 h). The data were analyzed using Kruskal-Wallis and Dunn post-hoc tests (p < 0.05). In both ADT and DCT, GuttaFlow 2 presented no effect against E. faecalis, while Endofill and AH Plus showed similar inhibition zones. Endofill was the only material capable of reducing bacterial growth in DCT. In conclusion, modifications in the silver particle of GuttaFlow 2 did not result in a sealer with antibacterial effect against E. faecalis.
Descritores: Materiais Restauradores do Canal Radicular/farmacologia
Prata/farmacologia
Enterococcus faecalis/efeitos dos fármacos
Dimetilpolisiloxanos/farmacologia
Resinas Epóxi/farmacologia
Guta-Percha/farmacologia
Antibacterianos/farmacologia
-Tamanho da Partícula
Materiais Restauradores do Canal Radicular/química
Silicones/farmacologia
Silicones/química
Prata/química
Fatores de Tempo
Teste de Materiais
Contagem de Colônia Microbiana
Reprodutibilidade dos Testes
Estatísticas não Paramétricas
Dimetilpolisiloxanos/química
Combinação de Medicamentos
Resinas Epóxi/química
Guta-Percha/química
Antibacterianos/química
Tipo de Publ: Research Support, Non-U.S. Gov't
Estudo Comparativo
Estudo de Avaliação
Responsável: BR1.1 - BIREME


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Id: biblio-952011
Autor: Alzraikat, Hanan; Taha, Nessrin Ahmad; Hassouneh, Layla.
Título: Dissolution of a mineral trioxide aggregate sealer in endodontic solvents compared to conventional sealers
Fonte: Braz. oral res. (Online);30(1):e16, 2016. tab, graf.
Idioma: en.
Projeto: Research Deanship, Jordan University of Science and Technology.
Resumo: Abstract The aim of this study is to evaluate the solubility of a Mineral Trioxide Aggregate sealer (MTA-Fillapex) compared with five other sealers, calcium hydroxide (Sealapex), resin (Realseal), zinc oxide-eugenol (Tubli-Seal), and two epoxy resins (AH-26 and AH-Plus), in chloroform and eucalyptoil in static and ultrasonic environments. Samples of each sealer were prepared (n = 180) and then divided into 12 groups that were immersed in solvents for 5 and 10 min in static and ultrasonic environments. The mean weight loss was determined, and the values were compared using Student's t-test, One-way ANOVA, and Tukey's HSD post-hoc test (p < 0.05). In chloroform, MTA-Fillapex, AH-26, and Sealapex displayed moderate solubility with no significant difference in dissolution (p = 0.125); however, their dissolution was significantly lower than that of AH-Plus (p < 0.001), which was almost fully dissolved after 10 minutes. Realseal was significantly less soluble than all sealers (p < 0.001). In eucalyptoil, MTA-Fillapex showed low solubility, as all of the sealers did, but Tubli-Seal was significantly more soluble than other sealers (p < 0.001). Using ultrasonic activation resulted in a significantly higher dissolution rate in chloroform for all sealers except MTA-Fillapex after 10 min (p = 0.226). In eucalyptoil, ultrasonic activation significantly increased the dissolution rate of all sealers except MTA-Fillapex after 5 and 10 min, Sealapex at 10 min, and AH-Plus at 5 min (p > 0.05). In conclusion, MTA-Fillapex was not sufficiently dissolved in either solvent. Ultrasonic activation had limited effectiveness on MTA-Fillapex dissolution, whereas it significantly increased the efficiency of solvents in dissolving a number of endodontic sealers.
Descritores: Óxidos/química
Materiais Restauradores do Canal Radicular/química
Solventes/química
Clorofórmio/química
Silicatos/química
Compostos de Cálcio/química
Compostos de Alumínio/química
Cicloexanóis/química
Monoterpenos/química
-Valores de Referência
Prata/química
Solubilidade
Fatores de Tempo
Titânio/química
Cimento de Óxido de Zinco e Eugenol/química
Bismuto/química
Teste de Materiais
Hidróxido de Cálcio/química
Salicilatos/química
Reprodutibilidade dos Testes
Análise de Variância
Combinação de Medicamentos
Resinas Epóxi/química
Ondas Ultrassônicas
Eucaliptol
Imersão
Tipo de Publ: Research Support, Non-U.S. Gov't
Estudo Comparativo
Estudo de Avaliação
Responsável: BR1.1 - BIREME


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Id: biblio-1289771
Autor: PAHO/WHO Collaborating Centre for Nursing Research DevelopmentSchneider, Guilherme; PAHO/WHO Collaborating Centre for Nursing Research DevelopmentBim, Felipe Lazarini; PAHO/WHO Collaborating Centre for Nursing Research DevelopmentSousa, Álvaro Francisco Lopes de; Watanabe, Evandro; PAHO/WHO Collaborating Centre for Nursing Research DevelopmentAndrade, Denise de; Fronteira, Inês.
Título: The use of antimicrobial-impregnated fabrics in health services: an integrative review / Utilização de têxteis impregnados com antimicrobianos nos serviços de saúde: revisão integrativa / Utilización de textiles impregnados con antimicrobianos en los servicios sanitarios: revisión integradora
Fonte: Rev. latinoam. enferm. (Online);29:e3416, 2021. tab, graf.
Idioma: en.
Resumo: Objective: to analyze evidence concerning the feasibility of antimicrobial-impregnated fabrics in preventing and controlling microbial transmission in health services. Method: an integrative review using the following databases: MEDLINE (via PubMed), Web of Science, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Scopus, and Latin American and Caribbean Health Sciences Literature (LILACS), regardless of language and date of publication. Seven studies were included in the analysis to verify the types of fabrics and substances used to impregnate the fabrics, applicability in health services, and decrease in microbial load. Results: silver nanoparticles and copper oxide are the main antimicrobial substances used to impregnate the fabrics. The patients' use of these fabrics, such as in bed and bath linens and clothing, was more effective in reducing antimicrobial load than in health workers' uniforms. Conclusion: the use of these antimicrobial-impregnated textiles, especially by patients, is a viable alternative to prevent and control microbial transmission in health services. Implementing these fabrics in health workers' uniforms requires further studies, however, to verify its effectiveness in decreasing microbial load in clinical practice.

Objetivo: analisar as evidências existentes sobre a viabilidade de utilizar têxteis impregnados com substâncias antimicrobianas na prevenção e no controle da transmissão microbiana em serviços de saúde. Método: revisão integrativa, utilizando as bases de dados MEDLINE (via PubMed), Web of Science, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Scopus e Literatura Latino-Americana em Ciências da Saúde (LILACS), sem restrição de idioma e período de publicação. Após a busca na literatura científica, foram selecionados sete estudos para análise quanto ao tipo de têxtil e substância utilizada para a impregnação, a aplicabilidade no serviço de saúde e a redução da carga microbiana. Resultados: nanopartículas de prata e óxido de cobre foram as principais substâncias antimicrobianas utilizadas para a impregnação de têxteis. A utilização desses têxteis pelos pacientes, como roupas de hotelaria e vestuário, mostrou maior eficácia na redução da carga microbiana em comparação ao uso como uniforme por profissionais de saúde. Conclusão: a utilização de têxteis impregnados com substâncias antimicrobianas, sobretudo pelos pacientes, pode ser considerada uma alternativa viável na prevenção e no controle da transmissão microbiana nos serviços de saúde. Todavia, a implementação destes têxteis, como uniforme para profissionais de saúde, ainda necessita de maiores investigações quanto à redução da carga microbiana na prática clínica.

Objetivo: analizar las evidencias existentes sobre la viabilidad de utilizar textiles impregnados con sustancias antimicrobianas en la prevención y control de la transmisión microbiana en servicios sanitarios. Método: revisión integradora, utilizando las bases de dados MEDLINE (vía PubMed), Web of Science, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Scopus y Literatura Latino-Americana em Ciências da Saúde (LILACS), sin restricción de idioma y período de publicación. Después de la búsqueda en la literatura científica, fueron seleccionados siete estudios para análisis en cuanto al tipo de textil y sustancia utilizada para impregnación, aplicabilidad en el servicio sanitario y reducción de la carga microbiana. Resultados: nanopartículas de plata y óxido de cobre fueron las principales sustancias antimicrobianas utilizadas para la impregnación de textiles. La utilización de esos textiles por los pacientes, como ropa de hotel y ropa, demostró mayor eficacia en la reducción de la carga microbiana en comparación al uso como uniforme por profesionales sanitarios. Conclusión: la utilización de textiles impregnados con sustancias antimicrobianas, sobre todo por los pacientes, puede ser considerada una alternativa viable en la prevención y control de la transmisión microbiana en los servicios sanitarios. Sin embargo, la implementación de estos textiles como uniforme para profesionales de la salud todavía necesita de mayores investigaciones en cuanto a la reducción de la carga microbiana en la práctica clínica.
Descritores: Roupa de Proteção
Prata
Têxteis
Região do Caribe
Contenção de Riscos Biológicos
Nanopartículas Metálicas
Serviços de Saúde
Anti-Infecciosos
Limites: Humanos
Tipo de Publ: Revisão
Responsável: BR26.1 - Biblioteca Central


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Id: biblio-1289844
Autor: Orellano, Pablo; Urdangarin, María del Huerto; Silva, Jenifer; Botto, Germán; González, Analía; Vucovich, Lilián; Peirano, Vivian.
Título: Nanopartículas de plata en el tratamiento de la micosis asociada al pie diabético / Silver nanoparticles to treat mycosis associated with diabetic foot / Nanopartículas de prata no tratamento da micose associada ao pé diabético
Fonte: Rev. méd. Urug;37(1):e37107, mar. 2021. tab, graf.
Idioma: es.
Resumo: Resumen: Una proporción importante de infecciones en el pie diabético consisten en onicomicosis y tinea pedis, problema común en el pie, amenazante de la viabilidad del tejido que puede provocar infecciones bacterianas secundarias. Requieren períodos prolongados de tratamiento antimicótico con alta tasas de recaídas y reinfección. Diversos estudios han mostrado la seguridad y eficacia de las nanopartículas de plata (NP Ag) como agente antimicrobiano. Realizamos un estudio donde se evaluó el tratamiento con NP Ag en dermatomicosis del pie de pacientes diabéticos. Método: estudio piloto, abierto, prospectivo, randomizado y controlado en pacientes que asisten a una policlínica de pie diabético. Dieciocho pacientes cumplieron con los criterios de inclusión conformándose dos grupos homogéneos. Ambos grupos recibieron tratamiento estándar que consistió en antimicótico tópico y desbastado mecánico. El grupo intervención utilizó un textil (medias) confeccionadas con hilos con NP Ag. Se realizó control clínico y microbiológico hasta las 12 semanas. Se evaluó el porcentaje de remisión y el tiempo hasta alcanzar el mismo. Resultados: predominó la onicomicosis y el germen Trichophyton rubrum. En el grupo intervención se logró un mayor porcentaje de remisión de lesiones y en un tiempo menor que el grupo control. Conclusiones: el uso de medias confeccionadas con hilos de NP Ag se asoció con una mayor probabilidad de curación completa en un período de 12 semanas a pesar de que el número de pacientes no permitió llegar al nivel de significación estadística, pudiendo contribuir a la prevención de infecciones o úlceras suplementarias en el pie diabético.

Summary: Onychomycosis and tinea pedis represent a significant proportion of infections in the diabetic foot, a common foot problem, and they constitute a threat to the viability of tissues that may provoke secondary bacterial infections. To combat them, antifungal treatments are required for long periods of time, the rates of relapse and reinfection being high. Several studies have proved the safety and effectiveness of silver nano particles (NP Ag) as an antimicrobial agent. A study was conducted to assess nanoparticle agents for foot dermatomycosis in diabetic patients. Method: pilot, open, prospective randomized and controlled study in patients who are assisted in a diabetic foot policlinic. 18 patients complied with the inclusion criteria and two homogeneous groups were formed. Both groups received standard treatment consisting in topic antifungal and mechanical roughing. The intervention groups used a textile (stockings) made with silver nanoparticle threads. Clinical and microbiological control was made during 12 weeks, also assessing the remission percentage and the time it took to achieve it. Resultados: onychomycosis and trichophyton rubrum prevailed. The intervention group showed a greater percentage of remission of lesions in a period of time that was shorter than that of the control group. Conclusions: the use of stockings made with NP Ag threads was associated with a greater probability of complete healing, in a 12-week period, despite the fact that the number of patients was not statistically significant. This could contribute to the prevention of supplementary infections or ulcers in the diabetic foot.

Resumo: Uma proporção significativa de infecções do pé diabético consiste em onicomicose e Tinea pedis, um problema comum nos pés que ameaça a viabilidade do tecido e pode causar infecções bacterianas secundárias. Requerem períodos prolongados de tratamento antifúngico com altas taxas de recidiva e reinfecção. Vários estudos têm demonstrado a segurança e a eficácia das nanopartículas de prata (NP Ag) como agente antimicrobiano. Realizamos um estudo onde o tratamento com NP Ag foi avaliado na dermatomicose do pé de pacientes diabéticos. Método: estudo piloto, aberto, prospectivo, randomizado e controlado em pacientes atendidos em uma policlínica de pé diabético. Dezoito pacientes preencheram os critérios de inclusão, formando dois grupos homogêneos. Ambos os grupos receberam tratamento padrão que consiste em antifúngico tópico e moagem mecânica. O grupo intervenção utilizou um tecido (meias) confeccionado com fios NP Ag. O controle clínico e microbiológico foi realizado até 12 semanas. A porcentagem de remissão e o tempo para alcançá-la foram avaliados. Resultados: predominaram a onicomicose e o germe Trichophyton rubrum. No grupo intervenção, obteve-se maior percentual de remissão das lesões e em menor tempo que o grupo controle. Conclusões: o uso de meias confeccionadas com fios NP Ag esteve associado a uma maior probabilidade de cura completa, no período de 12 semanas, apesar do número de pacientes não permitir atingir o nível de significância estatística, podendo contribuir para a prevenção de infecções ou úlceras adicionais no pé diabético.
Descritores: Prata/uso terapêutico
Onicomicose/terapia
Pé Diabético
Nanopartículas Metálicas/uso terapêutico
Responsável: UY6.1 - Biblioteca


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Id: biblio-1055379
Autor: Hussein, Elsayed Alsaied Masoud; Mohammad, Ali Al-Hajry; Harraz, Farid Abourageh; Ahsan, Mohd Faisal.
Título: Biologically Synthesized Silver Nanoparticles for Enhancing Tetracycline Activity Against Staphylococcus aureus and Klebsiella pneumoniae
Fonte: Braz. arch. biol. technol;62:e19180266, 2019. tab, graf.
Idioma: en.
Projeto: Deanship of Scientific Research, Najran University.
Resumo: Abstract Phytochemical content of plant extracts can be used effectively to reduce the metal ions to nanoparticles in one-step green synthesis process. In this study, six plant extracts were used for the synthesis of silver nanoparticles (AgNPs). Biologically synthesized AgNPs was characterized using UV-Vis Spectrophotometer, Field Emission Scanning Electron Microscope (FE-SEM), X-ray diffraction (XRD), Energy Dispersive X-ray spectroscopy (EDX) and Fourier Transform Infrared (FTIR) spectroscopy. The individual and combined effects of AgNPs and tetracycline against S. aureus and K. pneumoniae were assessed. Ginger, onion and sidr extracts supported AgNPs formation while arak, garlic and mint extracts failed to convert the silver ions to AgNPs. The present findings revealed significant differences between the tested plant extracts in supporting AgNPs synthesis. AgNPs synthesized by ginger showed the highest individual and combined activity against tested strains followed by AgNPs prepared by sidr then that synthesized by onion. AgNPs significantly enhanced tetracycline activity (p≤0.05) against S. aureus and K. pneumoniae. The results of this study demonstrated that the combination of tetracycline and biologically synthesized AgNPs presented a useful therapeutically method for the treatment of bacterial infection and counterattacking bacterial resistance.
Descritores: Prata/farmacologia
Staphylococcus aureus/efeitos dos fármacos
Tetraciclina/biossíntese
Extratos Vegetais/biossíntese
Klebsiella pneumoniae/efeitos dos fármacos
-Espectrometria por Raios X/instrumentação
Difração de Raios X/instrumentação
Espectrofotômetros/métodos
Espectroscopia de Infravermelho com Transformada de Fourier/instrumentação
Responsável: BR1.1 - BIREME


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Id: biblio-1056893
Autor: Vollú, Ana Lúcia; Moreira, Jessica Pronestino de Lima; Luiz, Ronir Raggio; Barja-Fidalgo, Fernanda; Fonseca-Gonçalves, Andrea.
Título: Survey of Knowledge, Attitudes and Practices of Brazilian Dentists Regarding Silver Diamine Fluoride
Fonte: Pesqui. bras. odontopediatria clín. integr;20:e4280, 2020. tab.
Idioma: en.
Projeto: Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro.
Resumo: Abstract Objective: Current acceptability, barriers to use, and clinical/teaching practices of Silver Diamine Fluoride (SDF) among Brazilian dentists were investigated. Material and Methods: A Google forms questionnaire was sent to dentists (n=10,500) to collect information about the use of SDF and the dentists' workplace, experience, specialty, and city of practice. A logistic regression model was performed. Results: From 409 respondents, 13.2% used SDF. Working at universities increased the use of SDF by 2.29 times (p=0.018) compared to private offices. Each training year, the chance of SDF usage increased by 3% (p=0.008). Pediatric dentists are more likely to use SDF (OR=6.76, p<0.001). There is no association between SDF usage and the city of practice. The majority (75.9%) indicated SDF for noncompliant patients. Dentists (75.9%) reported the exclusive use in deciduous teeth, while 24.1% also use in permanent teeth. The main barrier for non-users was a lack of knowledge (58.3%), while for users, tooth staining (90.7%) and parental acceptance (64.8%) were the complaints. Conclusion: The Silver Diamine Fluoride is not a common product used by the dentists from RJ. Its clinical applicability should be further disseminated; thus, lack of scientific knowledge would cease to be a problem in the use of SDF to arrest caries lesions.
Descritores: Brasil/epidemiologia
Cariostáticos
Conhecimentos, Atitudes e Prática em Saúde
Cárie Dentária
Odontólogos
-Prata
Modelos Logísticos
Estudos Transversais/métodos
Inquéritos e Questionários
Limites: Humanos
Tipo de Publ: Estudo Comparativo
Responsável: BR1264.1 - Biblioteca Setorial Prof Alberto M Campos


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Id: biblio-1132182
Autor: Almeida, Lariana Negrão Beraldo; Pietrobelli, Juliana Martins Teixeira Abreu; Lenzi, Giane Gonçalves; Santos, Onélia Aparecida Andreo.
Título: Degradation of Caffeine by Heterogeneous Photocatalysis Using ZnO with Fe and Ag
Fonte: Braz. arch. biol. technol;63:e20180614, 2020. tab, graf.
Idioma: en.
Resumo: Abstract The organic compound caffeine when detected in environmental matrices such as surface waters and groundwater is considered as an emerging contaminant, in which its effects are still unknown. Therefore, in the present research, zinc oxide-based catalysts impregnated with iron and silver were prepared for the reaction of caffeine degradation by heterogeneous photocatalysis. The wet impregnation method with excess solvent was applied to the preparation of the materials, later they were characterized by adsorption of N2, X-ray diffraction and photoacoustic spectroscopy. Then, the photodegradation, photolysis and adsorption tests were carried out, in which it was observed that only the presence of the radiation or photocatalysts could not sufficiently degrade the caffeine, however when combined radiation with all the catalysts studied here presented degradation above 70% at the end of 300 minutes of the reaction, and the best catalyst studied was that containing 8% Ag in non-calcined ZnO. Thus, these results point out that the methodology employed in this research, both for the preparation of the catalysts and in the process of the photocatalysis reaction, was efficient in the degradation of the emerging contaminant, caffeine, which could later be used for a mixture of other contaminants.
Descritores: Prata/química
Óxido de Zinco/química
Cafeína/química
Catálise
Processos Fotoquímicos
-Adsorção
Reatores Biológicos
Ferro/química
Responsável: BR1.1 - BIREME


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Id: lil-768559
Autor: Costa, Mariana Takahashi Ferreira; Gomes, Aline da Silva; Santos, Poliana Brito dos; Martins, Renata Soares; Moura, Sara Ribeiro; Scota, Sayonara; Oliveira, Andreia Cristine Deneluz Schunck de; Gamba, Mônica Antar; Nadal, Sidney Roberto.
Título: Giant condyloma acuminatum: report of surgical treatment and evolution of healing / Condiloma acuminado gigante: relato de tratamento cirúrgico e evolução da cicatrização
Fonte: DST j. bras. doenças sex. transm;27(1-2):48-53, 2015.
Idioma: en.
Resumo: O condiloma acuminado gigante, variante rara do condiloma acuminado anogenital, apresenta crescimento rápido associado a estados de imunodeficiência.Relatamos os resultados com os cuidados com a ferida operatória. Trata-se de homem de etnia negra, 55 anos, portador do vírus da imunodeficiência humana com condiloma acuminado acometendo desde as regiões inguinais até o sulco interglúteo, que foi ressecado permanecendo a ferida aberta para posterior enxertia. Os cuidados com essa ferida incluíram solução de polihexametileno biguanida/betaína, solução de ácidos graxos essenciais, hidrofibra/prata e película. Evoluiu com infecção secundária sendo a hidrofibra substituída por espuma de poliuretano/prata/ibuprofeno. Houve melhora da infecção e da dor, contração das bordas e presença de tecido de granulação em toda a lesão. Naquelas condições, o enxerto de pele foi realizado no 41º dia. A despeito dos possíveis vieses de confusão, pode-se inferir que esses cuidados prepararam o leito da ferida para receber o enxerto de pele.

Giant condyloma acuminatum, a rare variant of anogenital condyloma, shows rapid growth associated with immunodeficiency. Wound care after resection andoutcomes were reported. NGS, black, 55 years, HIV positive, with giant condyloma acuminatum affecting from the groin to the intergluteal groove, which wasresected, remaining the wound opened for later skin graft. Topical care included polihexametilene biguanide/betaine solution, essencial fatty acids solution,hydrofiber/silver, and poliuretane film. The wound developed secondary infection, so hidrofiber was replaced by polyurethane foam/silver/ibuprofen. Therewas improvement in infection and pain, contraction of the edges and the presence of granulation tissue across the lesion. In those conditions the skin graft was performed after 41 days. Despite possible confusion bias, it can be inferred that the care adopted prepared the wound bed to receive the skin graft.
Descritores: Cicatrização
Infecção dos Ferimentos
Condiloma Acuminado
Transplante de Pele
Tumor de Buschke-Lowenstein
-Prata
Betaína
Ácidos Graxos Essenciais
Ibuprofeno
HIV
Dor Pélvica
Limites: Humanos
Masculino
Pessoa de Meia-Idade
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


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Id: biblio-1132187
Autor: Gonçalves, Isabella Salgado; Viale, Ana Beatriz; Sormani, Natália Navarro; Pizzol, Karina Eiras Dela Coleta; Araujo-Nobre, Alyne Rodrigues de; Oliveira, Paula Chagas Silva de; Barud, Hélida Gomes de Oliveira; Antonio, Selma Gutierrez; Barud, Hernane da Silva.
Título: Antimicrobial Orthodontic Wires Coated with Silver Nanoparticles
Fonte: Braz. arch. biol. technol;63:e20190339, 2020. graf.
Idioma: en.
Projeto: FAPESP/CEPID; . CNPq.
Resumo: Abstract Conventional orthodontic treatment with the use of stainless steel may be detrimental to oral health by promoting demineralizing lesions appearance and increasing adhesion and formation of bacterial biofilm, inducing the development of cavities. An alternative that has been researched to reduce the side effects of orthodontic treatment is the coating of materials with antimicrobial nanoparticles. Nanometric- sized particles increase their surface area and contact with the microbial membrane, consequently intensifying their bacteriostatic and bactericidal effect. In this work, hydrothermal synthesis, a "green" process was used to attach silver nanoparticles (AgNPs) to the surface of two different brands of orthodontic wires. The coated materials were analyzed for their physicochemical properties by scanning electron microscopy (SEM), X-ray diffraction (XRD) and differential scanning calorimetry (DSC), which showed the distribution of AgNPs along the wires without modifying their properties. In the microbiological test, one of the brands showed a statistically significant difference in microbial adhesion and biofilm formation by Staphylococcus aureus and Streptococcus mutans. Results lead to the conclusion that antimicrobial orthodontic wires coated with silver nanoparticles through hydrothermal synthesis is a promising material for the improvement of orthodontic treatment.
Descritores: Fios Ortodônticos
Staphylococcus aureus/efeitos dos fármacos
Streptococcus mutans/efeitos dos fármacos
Nanopartículas Metálicas
Antibacterianos/farmacologia
-Prata
Aderência Bacteriana
Calorimetria
Microscopia Eletrônica de Varredura
Placa Dentária
Revestimentos
Responsável: BR1.1 - BIREME


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Id: biblio-1013358
Autor: Bernardo-Mazariegos, Erick; Valdez-Salas, Benjamín; González-Mendoza, Daniel; Abdelmoteleb, Ali; Tzintzun Camacho, Olivia; Ceceña Duran, Carlos; Gutiérrez-Miceli, Federico.
Título: Nanopartículas de plata de Justicia spicigera y sus potencialidades antimicrobianas en el control biológico de bacterias transmitidas por alimentos y hongos fitopatógenos / Silver nanoparticles from Justicia spicigera and their antimicrobial potentialities in the biocontrol of foodborne bacteria and phytopathogenic fungi
Fonte: Rev. argent. microbiol;51(2):103-109, jun. 2019. ilus, graf, tab.
Idioma: en.
Resumo: In the present work, the biosynthesis of silver-nanoparticles (AgNP) was evaluated using the aqueous extract from Justicia spicigera. The obtained silver nanoparticles were characterized using UV-visible spectroscopic techniques, energy dispersive X-ray spectrometers (EDS), zeta potential and dynamic light scattering. The antimicrobial activity of biosynthesized AgNP was tested against foodborne bacteria (Bacillus cereus, Klebsiella pneumoniae and Enterobacter aerogenes) and phytopathogenic fungi (Colletotrichum sp., Fusarium solani, Alternaria alternata and Macrophomina phaseolina). The elemental profile of synthesized nanoparticles using J. spicigera shows higher counts at 3 keV due to silver, confirming the formation of silver nanoparticles. Scanning electron microscopy (SEM) analysis showed a particle size between 86 and 100 nm with spherical morphology. AgNP showed effective antibacterial and antifungal activity against the tested organisms principally with B. cereus, K. pneumoniae, E. aerogenes, A. alternata and M. phaseolina. Therefore, further studies are needed to confirm the potential of AgNP from J. spicigera in the control of indicator organisms under field conditions.

En el presente trabajo se evaluó la biosíntesis de nanopartículas de plata (AgNP) en presencia de una sal de plata y extractos acuosos de Justicia spicigera. Las nanopartículas así obtenidas fueron caracterizadas mediante técnicas espectroscópicas UV-visibles, espectrómetros de rayos X de energía dispersiva (EDS), potencial zeta y dispersión de luz dinámica. La actividad antimicrobiana de las AgNP biosintetizadas se probó frente a diversas bacterias transmitidas por alimentos (Bacillus cereus, Klebsiella pneumoniae y Enterobacter aerogenes) y hongos fitopatógenos (Colletotrichum sp., Fusarium solani, Alternaria alternata y Macrophomina phaseolina). El perfil elemental de las nanopartículas sintetizadas utilizando el extracto de J. spicigera mostró valores altos a 3 keV, lo que confirma la formación de nanopartículas de plata. El análisis por microscopía electrónica de barrido (SEM) reveló un tamaño de partícula entre 86 y 100 nm, con morfología esférica. Las AgNP mostraron una actividad antibacteriana y antifúngica efectiva contra los organismos evaluados, principalmente contra B. cereus, K. pneumoniae, E. aerogenes, A. alternata y M. phaseolina. Se necesitan más estudios para confirmar el potencial de las AgNP derivadas de J. spicigera en el control de organismos indicadores en condiciones de campo.
Descritores: Prata/uso terapêutico
Controle Biológico de Vetores
Nanopartículas Metálicas/análise
-Doenças Transmitidas por Alimentos/microbiologia
Doenças Transmitidas por Alimentos/prevenção & controle
Anti-Infecciosos
Antifúngicos
Tipo de Publ: Ensaio Clínico
Responsável: AR635.1 - FCVyS - Servicio de Información y Documentación



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